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TGLGRHNGAMIAPTSSTTDHLKDPRPILDRAIATGGVVIAGVRPEQLTDPTPCTDMDVRALLAHLIGVLA RVAALGNGENPFAVTETSVADDRWLDAWRQSGRRAADAWSDDAVLERPMALPWIQGSGAEVLASYFSELT VHTWDLATATRQQPDWDDTVVAAAFDAARQILPAENRRALYEEISAARGLDEVAVPFAEAVPISDDAPAI DRLVAWNGRDPLRRF*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2932 | - | - | 100% (226) | hypothetical protein Mvan_2932 |
| M. vanbaalenii PYR-1 | Mvan_5694 | - | 3e-14 | 30.35% (201) | hypothetical protein Mvan_5694 |
| M. vanbaalenii PYR-1 | Mvan_1558 | - | 3e-10 | 28.21% (195) | hypothetical protein Mvan_1558 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1756 | - | 1e-12 | 29.79% (188) | hypothetical protein Mb1756 |
| M. gilvum PYR-GCK | Mflv_1118 | - | 3e-13 | 28.36% (201) | hypothetical protein Mflv_1118 |
| M. tuberculosis H37Rv | Rv1727 | - | 1e-12 | 29.79% (188) | hypothetical protein Rv1727 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3926 | - | 9e-13 | 28.57% (182) | hypothetical protein MAB_3926 |
| M. marinum M | MMAR_5328 | - | 3e-12 | 28.57% (217) | hypothetical protein MMAR_5328 |
| M. avium 104 | MAV_0248 | - | 8e-09 | 24.77% (218) | hypothetical protein MAV_0248 |
| M. smegmatis MC2 155 | MSMEG_6832 | - | 4e-08 | 29.15% (199) | hypothetical protein MSMEG_6832 |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_4409 | - | 3e-12 | 28.57% (217) | hypothetical protein MUL_4409 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1756|M.bovis_AF2122/97 --------------------------------------MDLYSN----LV
Rv1727|M.tuberculosis_H37Rv --------------------------------------MDLYSN----LV
MMAR_5328|M.marinum_M -------------------------MASDLRPGPDSPPTDELAS----AE
MUL_4409|M.ulcerans_Agy99 -------------------------MASDLRPGPDSPPTDELAS----AE
MAV_0248|M.avium_104 ----------------------MANMAPDLRPGPDSPPTDELDG----AE
MSMEG_6832|M.smegmatis_MC2_155 -----------------------MTYAGARASTPHWADMDELSS----AQ
Mvan_2932|M.vanbaalenii_PYR-1 --------------------MTGLGRHNGAMIAPTSSTTDHLKDPRPILD
Mflv_1118|M.gilvum_PYR-GCK -----------------------------------------MID----MT
MAB_3926|M.abscessus_ATCC_1997 MSASEEGQALMSASEEGRALMSASEEGRALMSASEEGRAATSGASAEDFA
Mb1756|M.bovis_AF2122/97 EAEQRLVALVSSIEADSYSSPTPCDRWDVRALLSHALASIDAFAAAVDGA
Rv1727|M.tuberculosis_H37Rv EAEQRLVALVSSIEADSYSSPTPCDRWDVRALLSHALASIDAFAAAVDGA
MMAR_5328|M.marinum_M RALAVLQQVLHPIGDGDLFRPTPCPEYDVSGLTGHLLNSIVVLGGMAG--
MUL_4409|M.ulcerans_Agy99 RALAVLQQVLHPIGDGDLFRPTPCPEYDVSGLTGHLLNSIVVLDGMAG--
MAV_0248|M.avium_104 AALRVMQQVLHPIAADDMPRPTPCAQFDVTRLTDHLLKSLEALGGMAG--
MSMEG_6832|M.smegmatis_MC2_155 SALSALRPVLSAITPDDCGLPTPCAGFDVAALGEHLVGTVRMVGAAAD--
Mvan_2932|M.vanbaalenii_PYR-1 RAIATGGVVIAGVRPEQLTDPTPCTDMDVRALLAHLIGVLARVAALGNG-
Mflv_1118|M.gilvum_PYR-GCK AACAGTAGLLDRVRDDQLSGATPCSGMDLGALVAHIGGLALAFDAAARKE
MAB_3926|M.abscessus_ATCC_1997 RASDAIEALLAAVRPDQWDAATPCEEWNLRQLADHLVEVNYSLAGRFGG-
* :: : . .*** :: * * . .
Mb1756|M.bovis_AF2122/97 PGPDMAQVFSGADIVGDDPLGATQRITRRSQAAWSTVRDLNAELSTFIGV
Rv1727|M.tuberculosis_H37Rv PGPDMAQVFSGADIVGDDPLGATQRITRRSQAAWSTVRDLNAELSTFIGV
MMAR_5328|M.marinum_M ----AEFT---MRDHTSSAEGQVVSAARPALDAWH-RRGMEGDVPLGPAS
MUL_4409|M.ulcerans_Agy99 ----AEFT---MRDHTSTPEGQVVSAARPALDAWH-RRGMDGDVPLGPAS
MAV_0248|M.avium_104 ----ADFPD--HADSADSVERRVIAVARPALDAWR-QRGLDGTVSFGGGE
MSMEG_6832|M.smegmatis_MC2_155 ----AGFVRFEVVSHDDDIEARVAASTEAVIAVWQ-RRGTAGEVVFAGRV
Mvan_2932|M.vanbaalenii_PYR-1 ---ENPFAVTETSVADDRWLDAWRQSGRRAADAWSDDAVLERPMALPWIQ
Mflv_1118|M.gilvum_PYR-GCK FGPLTDTPPEMGDGVEDGWRESYPSRLASLASAWREPAAWEGMSRAGGVD
MAB_3926|M.abscessus_ATCC_1997 ----------LSSGTAADPVAAYRLSAQALRDALALPGVLDQTYPGPFAH
.
Mb1756|M.bovis_AF2122/97 MPAGQALAIITFSTVVHGWDLAVATGQAGELPEHLAEAAQQVAAELVP-V
Rv1727|M.tuberculosis_H37Rv MPAGQALAIITFSTVVHGWDLAVATGQAGELPEHLAEAAQQVAAELVP-V
MMAR_5328|M.marinum_M MPARVAVSVFSIEFLVHAWDYATAVGHDIHVPDSLADYVLGLAQNLIQPH
MUL_4409|M.ulcerans_Agy99 MPARVAVSVFSIEFLVHAWDYATAVGHDIHVPDSLADYVLGLAQNLIQPH
MAV_0248|M.avium_104 MPARNACAILALELLVHAWDYARAVGRDARAPEPLAEYVLGLAHRVIRPE
MSMEG_6832|M.smegmatis_MC2_155 MPARLALGVLSVELVVHGWDFAQALHRPLGITAAHADFVLAMARHIITPA
Mvan_2932|M.vanbaalenii_PYR-1 GSGAEVLASYFSELTVHTWDLATATRQQPDWDDTVVAAAFDAARQILPAE
Mflv_1118|M.gilvum_PYR-GCK FPADVGGLIALTEVVVHGWDVAVSAGLPYEVDGETLAAVHGHLAAFTADG
MAB_3926|M.abscessus_ATCC_1997 TTGANQLQVRMADLLTHGWDLARATGASADLPVDLTENALGFVQKLAGAF
.. . .* ** * : . .
Mb1756|M.bovis_AF2122/97 LRPRG---------------LFAHDVDLAGEATPTQRLVALTGRKPR---
Rv1727|M.tuberculosis_H37Rv LRPRG---------------LFAHDVDLAGEATPTQRLVALTGRKPR---
MMAR_5328|M.marinum_M ERGAA---------------GFDDPVQVGDDVSGLHRLVAFTGRNPIR--
MUL_4409|M.ulcerans_Agy99 ERGAA---------------GFDDPVQVGDDVRGLHRLVAFTGRNPIR--
MAV_0248|M.avium_104 VRGQA---------------GFDDPVEVPADADALTKLVAFTGRNPAR--
MSMEG_6832|M.smegmatis_MC2_155 SRETA---------------GFDDPVSVAADAAALDRLVAYTGRTPRRWP
Mvan_2932|M.vanbaalenii_PYR-1 NRRALYEEISAARGLDEVAVPFAEAVPISDDAPAIDRLVAWNGRDPLRRF
Mflv_1118|M.gilvum_PYR-GCK PVEGL----------------FDAPVPVPDDAPLLDRVIAMTGRDPSWSA
MAB_3926|M.abscessus_ATCC_1997 ARSGK----------------FGAPQPVAEDAPALDRLAAMTGRVV----
* : :. :: * .**
Mb1756|M.bovis_AF2122/97 ------
Rv1727|M.tuberculosis_H37Rv ------
MMAR_5328|M.marinum_M ------
MUL_4409|M.ulcerans_Agy99 ------
MAV_0248|M.avium_104 ------
MSMEG_6832|M.smegmatis_MC2_155 SNMKSR
Mvan_2932|M.vanbaalenii_PYR-1 ------
Mflv_1118|M.gilvum_PYR-GCK A-----
MAB_3926|M.abscessus_ATCC_1997 ------