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MASKMDTETHYSDVWVVIPAFNEAAVIGKVVTDVRSVFDHVVCVDDGSTDGTGDIARRSGAHLVRHPINL GQGAAIQTGIEYARKQPGAQVFATFDGDGQHRVKDVAAMVDRLGAGDVDVVIGTRFGRPVGKASASRPPL MKRIVLQTGARLSRRGRRLGLTDTNNGLRVFNKTVADGLNITMSGMSHATEFIMLIAENHWRVAEEPVEV LYTEYSKSKGQPLLNGVNIIFDGFLRGRMPR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3631 | - | - | 100% (241) | POSSIBLE TRANSFERASE (POSSIBLY GLYCOSYLTRANSFERASE) |
| M. tuberculosis H37Rv | Rv2051c | ppm1 | 3e-12 | 25.88% (228) | polyprenol-monophosphomannose synthase Ppm1 |
| M. tuberculosis H37Rv | Rv0539 | - | 2e-08 | 28.10% (210) | dolichyl-phosphate sugar synthase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3655 | - | 1e-138 | 100.00% (241) | transferase |
| M. gilvum PYR-GCK | Mflv_3118 | - | 9e-12 | 24.69% (239) | dolichyl-phosphate beta-D-mannosyltransferase |
| M. leprae Br4923 | MLBr_00207 | - | 1e-110 | 81.78% (236) | putative glycosyltransferase |
| M. abscessus ATCC 19977 | MAB_0505c | - | 1e-83 | 62.82% (234) | putative glycosyl transferase |
| M. marinum M | MMAR_5131 | - | 1e-116 | 84.81% (237) | glycosyl transferase |
| M. avium 104 | MAV_0525 | - | 1e-108 | 84.89% (225) | glycosyl transferase |
| M. smegmatis MC2 155 | MSMEG_3859 | - | 1e-14 | 25.10% (239) | glycosyl transferase, group 2 family protein |
| M. thermoresistible (build 8) | TH_0733 | - | 2e-11 | 23.94% (213) | Polyprenol-monophosphomannose synthase Ppm1 |
| M. ulcerans Agy99 | MUL_4208 | - | 1e-117 | 84.65% (241) | glycosyl transferase |
| M. vanbaalenii PYR-1 | Mvan_3418 | - | 4e-10 | 24.69% (239) | dolichyl-phosphate beta-D-mannosyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Rv3631|M.tuberculosis_H37Rv ----------MASKMDTETHYSDVWVVIPAFNEAAVIGKVVTDVRSVFD-
Mb3655|M.bovis_AF2122/97 ----------MASKMDTETHYSDVWVVIPAFNEAAVIGKVVTDVRSVFD-
MMAR_5131|M.marinum_M --------------MDIDTHHPDVWIVVPAFNEATVIGEVIAQLRSTFG-
MUL_4208|M.ulcerans_Agy99 ----------MAVKMDIDTHHPDVWIVVPAFNEATVIGEVIAQLRSTFG-
MAV_0525|M.avium_104 --------------------------MIPAFNEAAVIGEVIADVRSVFD-
MLBr_00207|M.leprae_Br4923 --------------MGIETCYPGVWIVIPAFNEAAIIGEVVTDVRAVFD-
MAB_0505c|M.abscessus_ATCC_199 ---------------MSNTGNTDVWLVIPAYNEGPVIADVIAAALGTFP-
Mflv_3118|M.gilvum_PYR-GCK MSVPGGVTGREEPAG---RPSARTLVIIPTYNERDNLLSIVSRVNDAAPD
Mvan_3418|M.vanbaalenii_PYR-1 MSVPGGMTDGPGPGT---RPSDRTLVIIPTYNERQNLPLIVGRVHQARPD
MSMEG_3859|M.smegmatis_MC2_155 MSVPGEREQGAGEDPATVRPTQRTLVIIPTYNERENLPLIVGRVHHACPQ
TH_0733|M.thermoresistible__bu --------------------------------------------------
Rv3631|M.tuberculosis_H37Rv -HVVCVDDGSTDGTGDIARRS------GAHLVRHPINLGQGAAIQTGIEY
Mb3655|M.bovis_AF2122/97 -HVVCVDDGSTDGTGDIARRS------GAHLVRHPINLGQGAAIQTGIEY
MMAR_5131|M.marinum_M -HVVCVDDGSTDGTGDIALRA------GAHVVAHPINLGQGAAIQTGVEY
MUL_4208|M.ulcerans_Agy99 -HVVCVDDGSTDGTGDIALRA------GAHVVAHPINLGQGAAIQTGVEY
MAV_0525|M.avium_104 -NVVCVDDGSTDDTGEIARRA------GAHLVRHPINLGQGAAIQTGVEY
MLBr_00207|M.leprae_Br4923 -HVVCVDDGSADGTGEIALRA------GAHLVRHPVNLGQGAAIQTGVEY
MAB_0505c|M.abscessus_ATCC_199 -NIVCVDDGSVDRTAALAHGA------GAHVVRHPVNLGQGAAIQTGVEY
Mflv_3118|M.gilvum_PYR-GCK VHVLIVDDGSPDGTGELADELALGDPDRIHVMHRTSKDGLGAAYLAGFAW
Mvan_3418|M.vanbaalenii_PYR-1 VDILIVDDDSPDGTGQLADELSVADPDRIHVMHRTAKEGLGAAYLAGFAW
MSMEG_3859|M.smegmatis_MC2_155 VHILVVDDGSPDGTGALADELALADPDRVHVMHRTSKAGLGAAYLAGFDW
TH_0733|M.thermoresistible__bu VHVLIVDDGSPDGTGELADELALADPDRVHVMHRASKAGLGAAYLAGFRW
.:: ***.* * *. :* *:: :. : * *** :*. :
Rv3631|M.tuberculosis_H37Rv ARKQPGAQVFATFDGDGQHRVKDVAAMVDRLGAGDVDVVIGTRFGRPVGK
Mb3655|M.bovis_AF2122/97 ARKQPGAQVFATFDGDGQHRVKDVAAMVDRLGAGDVDVVIGTRFGRPVGK
MMAR_5131|M.marinum_M ARKQPGAQIFATFDADGQHRVKDLAAMVHRLSVGDVDVVIGTRFGRPVG-
MUL_4208|M.ulcerans_Agy99 ARKQPGAQIFATFDADGQHRVKDLAAMVHRLSVGDVDVVIGTRFGRPVG-
MAV_0525|M.avium_104 ARRQPGAQVFATFDADGQHRVKDLAAMVNRLRVGDVDVVIGTRFGTRQG-
MLBr_00207|M.leprae_Br4923 ARRQPAAQVFATFDADGQHRVKDLAALVDRLGAHDVDVVIGTRFGRLDGG
MAB_0505c|M.abscessus_ATCC_199 ARAQPGAQIFVTFDADGQHQVKDVVAMVDRLRLEPLDIIVGTRFGAGSGP
Mflv_3118|M.gilvum_PYR-GCK GLNR-EYTVLVEMDADGSHAPEDLHRLLAEIDAG-ADVVIGSRYVEGGD-
Mvan_3418|M.vanbaalenii_PYR-1 GLGR-QYTVLVEMDADGSHPPEQLARLLDAVDAG-ADVVIGSRYVSGGE-
MSMEG_3859|M.smegmatis_MC2_155 GLRR-GYSVLVEMDADGSHAPEELSRLLDAVDAG-ADLAIGSRYVPGGT-
TH_0733|M.thermoresistible__bu GLNR-QYSVLVEMDADGSHAPEELHRLLDAVDAG-ADLAIGSRYVDGGQ-
. : ::. :*.**.* ::: :: : *: :*:*:
Rv3631|M.tuberculosis_H37Rv --ASASRPPLMKRIVLQTGARLSRRGRRLGLTDTNNGLRVFNKTVADGLN
Mb3655|M.bovis_AF2122/97 --ASASRPPLMKRIVLQTGARLSRRGRRLGLTDTNNGLRVFNKTVADGLN
MMAR_5131|M.marinum_M -----SRPPLLKRIVLQTAARLSPRGRRLGLTDTNNGLRVFNKTVADGLN
MUL_4208|M.ulcerans_Agy99 -----SRPPLLKRIVLQTAARLSPRGRRLGLTDTNNGLRVFNKTVADGLN
MAV_0525|M.avium_104 -----ARPPLVKRMVLQTAARLSRRGRRLGLTDTNNGLRVFNKKVADGLD
MLBr_00207|M.leprae_Br4923 RLPILKGPPFLKRVVLRTAARLSRRGRRLGLTDTNNGLRVFNKKVADGLD
MAB_0505c|M.abscessus_ATCC_199 -----GHVPLIKRIVLKTVVLLSPRTRRLNLTDAHNGLRVFNRTVANGLN
Mflv_3118|M.gilvum_PYR-GCK ----VRNWPRRRMVLSRTANAYSRILLGVDIHDITAGYRAYRREVLEKID
Mvan_3418|M.vanbaalenii_PYR-1 ----VVNWPRRRLVLSRTANGYSRILLGVDIHDITAGYRAYRREVLEKID
MSMEG_3859|M.smegmatis_MC2_155 ----VRNWPWRRLVLSKTANTYSRFLLGVGIHDITAGYRAYRREVLEKID
TH_0733|M.thermoresistible__bu ----VRNWPRRRLLLSRTANTYSRLLLGVDIRDITAGYRAYRREVLEKID
* : :: :* * :.: * * *.:.: * : ::
Rv3631|M.tuberculosis_H37Rv ITMS---GMSHATEFIMLIAENHWRVAEEPVEVLYTEYSKS--KGQPLLN
Mb3655|M.bovis_AF2122/97 ITMS---GMSHATEFIMLIAENHWRVAEEPVEVLYTEYSKS--KGQPLLN
MMAR_5131|M.marinum_M ITMS---GMSHATEFVMLIAENHWRVAEEPVEVLYTDYSKS--KGQPLLN
MUL_4208|M.ulcerans_Agy99 ITMS---GMSHATEFVMLIAENHWRVAEEPVEVLYTDYSKS--KGQPLLN
MAV_0525|M.avium_104 ITMS---GMSHANEFVMLIDENHWRVVEEPIEVLYTEYSRS--KGQPLLN
MLBr_00207|M.leprae_Br4923 ITMT---GMSHANEFVMLIADNHWRVDEVPVEVLYTEYSKS--KGQPLLN
MAB_0505c|M.abscessus_ATCC_199 ITMN---GMGHASEFIAMISENHWRVAEQPVDILYTEYSMA--KGQSLIN
Mflv_3118|M.gilvum_PYR-GCK LAAVDSKGYGFQVDLTWRSINAGFTVVEVPITFTEREHGVSKMDGSTIRE
Mvan_3418|M.vanbaalenii_PYR-1 LAAVDTKGYGFQVDLTWRSINAGFTVIEVPITFTEREHGVSKMDGSTIRE
MSMEG_3859|M.smegmatis_MC2_155 LSAVDSKGYCFQIDLTWRAINNGFSVVEVPITFTERELGVSKMSGSNIRE
TH_0733|M.thermoresistible__bu LDAVDSKGYCFQIDLTWRAINHGFKVVEVPITFTERELGQSKMSGSNIRE
: * . :: : : * * *: . : . : .*. : :
Rv3631|M.tuberculosis_H37Rv GVNIIFDGFLRGRMPR------
Mb3655|M.bovis_AF2122/97 GVNIIFDGFLRGRMPR------
MMAR_5131|M.marinum_M GVNIIFDGFLRGRIRR------
MUL_4208|M.ulcerans_Agy99 GVNIIFDGFLRGRIRR------
MAV_0525|M.avium_104 GVNIIFDGFLRGRIPR------
MLBr_00207|M.leprae_Br4923 GVNIIFDGFLRGRMPK------
MAB_0505c|M.abscessus_ATCC_199 GVNIMFDTAFRRRLP-------
Mflv_3118|M.gilvum_PYR-GCK AIIKVAQWGMRARIDRARGNTP
Mvan_3418|M.vanbaalenii_PYR-1 AIIKVAQWGLRARLDRARGTTR
MSMEG_3859|M.smegmatis_MC2_155 AMFKVAEWGIRGRLDRARGVVR
TH_0733|M.thermoresistible__bu AIFKVAEWGIRGRLDRARGIVR
.: : : :* *: