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KLGAWVAAQLPTTRTAVRTRLTRLVVSIVAGLLLYASFPPRNCWWAAVVALALLAWVLTHRATTPVGGLG YGLLFGLVFYVSLLPWIGELVGPGPWLALATTCALFPGIFGLFAVVVRLLPGWPIWFAVGWAAQEWLKSI LPFGGFPWGSVAFGQAEGPLLPLVQLGGVALLSTGVALVGCGLTAIALEIEKWWRTGGQGDAPPAVVLPA ACICLVLFAAIVVWPQVRHAGSGSGGEPTVTVAVVQGNVPRLGLDFNAQRRAVLDNHVEETLRLAADVHA GLAQQPQFVIWPENSSDIDPFVNPDAGQRISAAAEAIGAPILIGTLMDVPGRPRENPEWTNTAIVWNPGT GPADRHDKAIVQPFGEYLPMPWLFRHLSGYADRAGHFVPGNGTGVVRIAGVPVGVATCWEVIFDRAPRKS ILGGAQLLTVPSNNATFNKTMSEQQLAFAKVRAVEHDRYVVVAGTTGISAVIAPDGGELIRTDFFQPAYL DSQVRLKTRLTPATRWGPILQWILVGAAAAVVLVAMRQNGWFPRPRRSEPKGENDDSDAPPGRSEASGPP ALSESDDELIQPEQGGRHSSGFGRHRATSRSYMTTGQPAPPAPGNRPSQRVLVIIPTFNERENLPVIHRR LTQACPAVHVLVVDDSSPDGTGQLADELAQADPGRTHVMHRTAKNGLGAAYLAGFAWGLSREYSVLVEMD ADGSHAPEQLQRLLDAVDAGADLAIGSRYVAGGTVRNWPWRRLVLSKTANTYSRLALGIGIHDITAGYRA YRREALEAIDLDGVDSKGYCFQIDLTWRTVSNGFVVTEVPITFTERELGVSKMSGSNIREALVKVARWGI EGRLSRSDHARARPDIARPGAGGSRVSRADVTE*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. tuberculosis H37Rv | Rv2051c | ppm1 | - | 100% (874) | Polyprenol-monophosphomannose synthase Ppm1 |
M. tuberculosis H37Rv | Rv0539 | - | 6e-16 | 32.74% (223) | dolichyl-phosphate sugar synthase |
M. tuberculosis H37Rv | Rv3631 | - | 1e-11 | 25.88% (228) | transferase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2077c | ppm1 | 0.0 | 100.00% (874) | polyprenol-monophosphomannose synthase Ppm1 |
M. gilvum PYR-GCK | Mflv_3117 | - | 0.0 | 62.80% (535) | apolipoprotein N-acyltransferase |
M. leprae Br4923 | MLBr_01441 | - | 0.0 | 73.78% (534) | putative apolipoprotein N-acyltransferase |
M. abscessus ATCC 19977 | MAB_2206 | - | 1e-180 | 58.21% (548) | polyprenol-phosphate-mannose synthase 2 |
M. marinum M | MMAR_3029 | ppm1A | 0.0 | 74.21% (605) | polyprenol-monophosphomannose synthase, Ppm1A |
M. avium 104 | MAV_4605 | - | 2e-18 | 34.10% (217) | glycosyltransferase |
M. smegmatis MC2 155 | MSMEG_3860 | - | 0.0 | 62.52% (539) | polyprenol-monophosphomannose synthase Ppm1 |
M. thermoresistible (build 8) | TH_0732 | - | 0.0 | 61.02% (549) | Polyprenol-monophosphomannose synthase Ppm1 |
M. ulcerans Agy99 | MUL_5127 | ppm1A | 0.0 | 74.05% (605) | N-term polyprenol-monophosphomannose synthase Ppm1A |
M. vanbaalenii PYR-1 | Mvan_3419 | - | 0.0 | 63.18% (535) | apolipoprotein N-acyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment Rv2051c|M.tuberculosis_H37Rv -------------------------------------------------- Mb2077c|M.bovis_AF2122/97 -------------------------------------------------- Mflv_3117|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3419|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_0732|M.thermoresistible__bu ------MADRGRRDRRAPGRRSGPTSGPTSGPTSGPASGPTRSEPPTDPI MSMEG_3860|M.smegmatis_MC2_155 ------MADDRARRFDRFRVRPEEITEVIPAVTD---------------- MAB_2206|M.abscessus_ATCC_1997 ------MADETVEES-VAETRGDEVADLG--------------------- MMAR_3029|M.marinum_M MARDWLGRERLPVDAQEDNPEVVQPEPGVDQTGPLGDEREPDADTADPGD MUL_5127|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01441|M.leprae_Br4923 -------------------------------------------------- MAV_4605|M.avium_104 -------------------------------------------------- Rv2051c|M.tuberculosis_H37Rv ----------------------------MKLGAWVAAQLP---------- Mb2077c|M.bovis_AF2122/97 ----------------------------MKLGAWVAAQLP---------- Mflv_3117|M.gilvum_PYR-GCK --------------------------MGETAADADAPERPTRAR------ Mvan_3419|M.vanbaalenii_PYR-1 -----------------------------------MADTPGRVT------ TH_0732|M.thermoresistible__bu GFDPITDDPAEDPAEDPAEDPAGDDPVEDPATDEPATDEPSRADTAEPGD MSMEG_3860|M.smegmatis_MC2_155 ------DDPLEDPLDDDVAP--GLDDAEPEPEPRDEHDEPSRPATG---S MAB_2206|M.abscessus_ATCC_1997 ------GERTEDSIAD---------EPEAPAETGPSRGKLFAAAVG---- MMAR_3029|M.marinum_M DAAIADDLAEEQDEAQDEAQDSETEAETTQVSAGPSAAVRLGTAARQGLV MUL_5127|M.ulcerans_Agy99 -------------------------------------------------M MLBr_01441|M.leprae_Br4923 ---MVDEIIEIDPVDDDPVNG------AFATLAVPSRVVKLRATVCHALA MAV_4605|M.avium_104 -------------------------------------------------- Rv2051c|M.tuberculosis_H37Rv -----------TTRTAVRTRLTRLVVSIVAGLLLYASFPPRNCWWAAVVA Mb2077c|M.bovis_AF2122/97 -----------TTRTAVRTRLTRLVVSIVAGLLLYASFPPRNCWWAAVVA Mflv_3117|M.gilvum_PYR-GCK -----------RFGQAVVDRLPRLTAAIVAGLALCVSFPPFGWWYIAILA Mvan_3419|M.vanbaalenii_PYR-1 -----------RLVRAVADRWHVLSLTIAAGLLLCASFPPIGWWFTAILA TH_0732|M.thermoresistible__bu RPADRLIRFAHRAGRAVLDRLPQLGLTVLAGLLLCVSFPPMGWWYLAPVA MSMEG_3860|M.smegmatis_MC2_155 RIGGWVARRGSRFGKGVLDRCAPLSAAIGGGLALWLSFPPIGWWFTAFPG MAB_2206|M.abscessus_ATCC_1997 -------ARIVAFGRAWMRTATRQGAALIAGLALCASFPPWGFWWAAFPA MMAR_3029|M.marinum_M AFGAGAAARLPGLWAATRPRLVRLVVSLVAGFLMYASFPPTNWWWAAIVS MUL_5127|M.ulcerans_Agy99 AFGAGAAARLPGLWAATRPRLVRLVVSLVAGFLMYASFPPTNWWWAAIVS MLBr_01441|M.leprae_Br4923 QMGVATVARVPATWAMLVPRLPRLVVAVVAGLLFCASFPSLNWWWAAVVA MAV_4605|M.avium_104 -------------------------------------------------- Rv2051c|M.tuberculosis_H37Rv LALLAWVLTHRATTPVGGLGYGLLFGLVFYVSLLPWIGELVGPGPWLALA Mb2077c|M.bovis_AF2122/97 LALLAWVLTHRATTPVGGLGYGLLFGLVFYVSLLPWIGELVGPGPWLALA Mflv_3117|M.gilvum_PYR-GCK FAVLGWVLTRERTTVAGGAGYGLLFGLAFYVPLLPWISGLVGAVPWLALS Mvan_3419|M.vanbaalenii_PYR-1 FAVFGWVLTRNSTTVAGGAGYGLLFGVAFYVPLLPWISGLVGAVPWLALS TH_0732|M.thermoresistible__bu LALLGGVLVHRATTLAGGFGYGVLFGLAFHIPLLPWISGLVGAVPWLALS MSMEG_3860|M.smegmatis_MC2_155 LALLGWVLTRTATTKAGGFGYGVLFGLAFYVPLLPWISGLVGAVPWLALA MAB_2206|M.abscessus_ATCC_1997 LSVLGLVLWSPRTTLRGGLGYGLLFGLAFFIPLLPWTGQLVGAVPWLALS MMAR_3029|M.marinum_M VALLTWVLMHPTTTPVGGLGYGFVFGLACFVPLLPWIGTLVGPVPWLVLA MUL_5127|M.ulcerans_Agy99 VALLTWVLMHPASTPVGGLGYGFVFGLACFVPLLPWIGTLVGPVPWLVLA MLBr_01441|M.leprae_Br4923 FALLAWVLTHPTTTPVGGLGYGFLFGLAFYLPLLSWISSLVGATPWWALA MAV_4605|M.avium_104 --------------MPGADGR-----VTVVLPCLNEEESLPG-------- *. * :. :. * * * Rv2051c|M.tuberculosis_H37Rv TTCALFPGIFGLFAVVVRLLPGWPIWFAVGWAAQEWLKSILPFGGFPWGS Mb2077c|M.bovis_AF2122/97 TTCALFPGIFGLFAVVVRLLPGWPIWFAVGWAAQEWLKSILPFGGFPWGS Mflv_3117|M.gilvum_PYR-GCK VVEALFCALFGMLAVVVRRLPGWPLWFAGLWSAQEWLKSTVPFGGFPWGV Mvan_3419|M.vanbaalenii_PYR-1 FAEALFPALFGMAAVAIRRLPGWPLWFAGLWSAQEWLKSAVPFGGFPWGT TH_0732|M.thermoresistible__bu VVQAVFPGLFGLAAVAVRRLPGRPVWFALLWVAYEWIKSSVPFGGFPWGV MSMEG_3860|M.smegmatis_MC2_155 FAESLFCGLFGLGAVVVVRLPGWPLWFATLWVAAEWAKSTFPFGGFPWGA MAB_2206|M.abscessus_ATCC_1997 LLCALWVALFGLLAVAVRNLPGWPLWFAAAWSATEWGKASIPFGGFPWGR MMAR_3029|M.marinum_M TTSALFPGLFGLSAVVVRRLPGWPIWFAVLWGAQEWLKSIVPFGGFPWGS MUL_5127|M.ulcerans_Agy99 TTSALFPGLFGLSAVVVRRLPGWPIWFAVLWGAQEWLKSIVPFGGFPWGS MLBr_01441|M.leprae_Br4923 TAAAFLPGFFGLLAVVVGPLPGWPIWFAVVWAAQEWLKSVVPFGGFPWGS MAV_4605|M.avium_104 --------------VLATIPPGYRALVVDNNSTDDTAGVARRHG------ * ** .. : : .* Rv2051c|M.tuberculosis_H37Rv VAFGQAEGPLLPLVQLGGVALLSTGVALVGCGLTAIALEIEKWWRT---- Mb2077c|M.bovis_AF2122/97 VAFGQAEGPLLPLVQLGGVALLSTGVALVGCGLTAIALEIEKWWRT---- Mflv_3117|M.gilvum_PYR-GCK VGFSQSESPLLPLAYVGGAPLVSFALVLLAFSLGALVLGVADWWRR---- Mvan_3419|M.vanbaalenii_PYR-1 VAFSQTESPLLPLAYVGGAPLVSFAVVLLAFSLAALVFAVADWWRR---- TH_0732|M.thermoresistible__bu VAYSQTNGPLLALAQIGGAPLVSFAVALTGFSLAALTAAIVRWWRS---- MSMEG_3860|M.smegmatis_MC2_155 SSYGQTNGPLLALARIGGAPLVSFAVALIGFSLTLLTAQIVWWWR----- MAB_2206|M.abscessus_ATCC_1997 VAFGQGDSPMLGLARYGGAPLVSFAVALGAFAVTALGIEMYRWWRS---- MMAR_3029|M.marinum_M VAFGQVDGPLLPLAQLGGVPLLSTGVVLVGSSFAAIALEIEKWWRTGSPA MUL_5127|M.ulcerans_Agy99 VAFGQVDGPLLPLAQLGGVPLLSTGVALVGSSFAAIALEIEKWWRTGSPA MLBr_01441|M.leprae_Br4923 VAFGQADGPLLPLAQLGGAPLLSMAIVLVGCSTTAIALEVVKWWRS---- MAV_4605|M.avium_104 -------AQVVTETRAG--------------------------------- . :: . * Rv2051c|M.tuberculosis_H37Rv -------GGQG---DAPPAVVLPAACICLVLFAAIVVWPQVRHAGSGSGG Mb2077c|M.bovis_AF2122/97 -------GGQG---DAPPAVVLPAACICLVLFAAIVVWPQVRHAGSGSGG Mflv_3117|M.gilvum_PYR-GCK ------DAATR--AATPPAVVLPGLCIAVVVLASTLAWPHVRKAGLGAGD Mvan_3419|M.vanbaalenii_PYR-1 ------DATAR--AAAPPAVVLPGLCITLVLLAATLAWPNVRKSGLGAGD TH_0732|M.thermoresistible__bu ------DSHR----AAPPAVVLPGLCIAAVLLATAVVWPQVRYSGAGADA MSMEG_3860|M.smegmatis_MC2_155 ------HGHKP--GVPAPAVMLPGVAIAASLLVTALVWPQVRQSGTGAGD MAB_2206|M.abscessus_ATCC_1997 ------PSVGPDGARPMPSVLLPGVCVCLVLFAMAISWQQVRHASHGATD MMAR_3029|M.marinum_M APQADPEAAQPVEPAKPPAVLLPGITVCLVLFAAVIVWPQVRHAGAGSGG MUL_5127|M.ulcerans_Agy99 APQADPEAAQPVEPAKPPAVLLPGITVCLVLFAAVIVWPQVRHAGAGSGG MLBr_01441|M.leprae_Br4923 -------SGQSNRSDPPPAVVLPGVCVCLVLLAVVVVWPQVRHAGAGSGG MAV_4605|M.avium_104 ----------------------YGAAVHAGVLAATTPIVAVLDADGSMDG . : ::. * :. . Rv2051c|M.tuberculosis_H37Rv -EPTVTVAVVQGNVPRLGLDFNAQRRAVLDNHVEETLRLAADVHAGLAQQ Mb2077c|M.bovis_AF2122/97 -EPTVTVAVVQGNVPRLGLDFNAQRRAVLDNHVEETLRLAADVHAGLAQQ Mflv_3117|M.gilvum_PYR-GCK -EPPVTVAAVQGNVPRLGLEFNAQRRAVLDNHVRETLRLADDVRAGRVPQ Mvan_3419|M.vanbaalenii_PYR-1 -EPPVTVAAVQGNVPRLGLDFNAQRRAVLDNHVRETLRLAEDVRAGRAPQ TH_0732|M.thermoresistible__bu ADQPIRVAAVQGNVPRLGLDFNAQRRAVLDNHVRETMRLAEDVRAGRAEQ MSMEG_3860|M.smegmatis_MC2_155 -DTAVTVAAVQGNVPRLGLEFNAQRRAVLDNHVKETLRLADDVKAGRAAQ MAB_2206|M.abscessus_ATCC_1997 -GRTVTVAAVQGNVPRLGLDFNAQRRAVLDYHVKETVLLAQDVKAGKAPA MMAR_3029|M.marinum_M -EPTITVAVVQGNVPRLGLDFNAQRRAVLDNHVRETLELAEDVRAGLAPQ MUL_5127|M.ulcerans_Agy99 -EPTITVAVVQGNVPRLGLDFNAQRRAVLDNHVRETLELAEDVRADLAPQ MLBr_01441|M.leprae_Br4923 -EPVITVAAVQGNVPRLGLDFNAQRRAVLDNHVHETLRLAEDVRAGIVPQ MAV_4605|M.avium_104 -----------ADLPRLVAALEAG----------------ADLVTGRRRP .::*** ::* *: :. Rv2051c|M.tuberculosis_H37Rv PQFVIWPENSSDIDPFVNPDAGQRISAAAEAIGAPILIGTLMDVPGRPR- Mb2077c|M.bovis_AF2122/97 PQFVIWPENSSDIDPFVNPDAGQRISAAAEAIGAPILIGTLMDVPGRPR- Mflv_3117|M.gilvum_PYR-GCK PMLVVWPENSSDIDPIANPDAAQEISRAAAAIDAPVLVGGVVAAPGYSR- Mvan_3419|M.vanbaalenii_PYR-1 PMLVVWPENSSDIDPLANADASREISTAADAINAPILVGGVVAAPGYSR- TH_0732|M.thermoresistible__bu PLFVVWPENSSDIDPLANPDAHQQISAAAAAIRAPILVGGVVRAPGYRP- MSMEG_3860|M.smegmatis_MC2_155 PMFVIWPENSSDIDPLLNADASAQITTAAEAIDAPILVGGVVRADGYTP- MAB_2206|M.abscessus_ATCC_1997 PQFVVWPENSSDIDPIRNADAAEAINEAAQAIGVPILVGGVLRHPDSTP- MMAR_3029|M.marinum_M PQFVIWPEDSSDIDPLINPDAAQQISKAAVAIGAPILVGTVLDAPGSSQK MUL_5127|M.ulcerans_Agy99 PQFVIWPEDSSDIDPLINPDAAQQISKAAVAIGAPILVGTVLDAPGSSQK MLBr_01441|M.leprae_Br4923 PQFVIWPENASDIDPLVNGDAGQEITVAAATIDAPILVGTVLDVQGPVP- MAV_4605|M.avium_104 VRGLRWPWVAR--------------------------VG----------- : ** : :* Rv2051c|M.tuberculosis_H37Rv --ENPEWTNTAIVWNPGTGPADRHDKAIVQPFGEYLPMPWLFRHLSGYAD Mb2077c|M.bovis_AF2122/97 --ENPEWTNTAIVWNPGTGPADRHDKAIVQPFGEYLPMPWLFRHLSGYAD Mflv_3117|M.gilvum_PYR-GCK --DNPVSNNTVIVWNPETGPSDRHDKRIVQPFGEYLPWRSFFSKLSSYAD Mvan_3419|M.vanbaalenii_PYR-1 --TNPVSNNTVIVWNPETGPGDRHDKRIVQPFGEYLPWRDFFSKLSPYAD TH_0732|M.thermoresistible__bu --DNPVATNSVLVWDPETGPTDRHDKQIVQPFGEYLPWRDFFRRLSPYAD MSMEG_3860|M.smegmatis_MC2_155 --DNPVANNTVIVWEPTDGPGERHDKQIVQPFGEYLPWRGFFKHLSSYAD MAB_2206|M.abscessus_ATCC_1997 --EQPKSINSIIVWDPNTGPGERHDKQIVQPFGEYLPWRSFFAHFSEYAD MMAR_3029|M.marinum_M NLENAEYTNTVLVWNPTTGPGDRHDKEIVQPFGEYLPMPWLFRHLSGYAD MUL_5127|M.ulcerans_Agy99 NLENAEYTNTVLVWNPTTGPGDRHDKEIVQPFGEYLPMPWLFRHLSGYAD MLBr_01441|M.leprae_Br4923 --QAPEYTNTVIVWNPGTGPADRHDKEIVQPFGEYLPMPWLFKRLSKYAD MAV_4605|M.avium_104 --------TVVMSWRLRTRHG--------LPVHDIAPMR----------- . : * *. : * Rv2051c|M.tuberculosis_H37Rv RAGHFVPGNG--TGVVRIAGVPVGVATCWEVIFDRAPRKSILGGAQLLTV Mb2077c|M.bovis_AF2122/97 RAGHFVPGNG--TGVVRIAGVPVGVATCWEVIFDRAPRKSILGGAQLLTV Mflv_3117|M.gilvum_PYR-GCK RAGYFVPGDG--DGVVEAAGIPVGITTCWEVIFDRAARESVRNGAQLLAV Mvan_3419|M.vanbaalenii_PYR-1 RAGYFVPGDG--DGVVQAAGVPVGITTCWEVIFDRAARQSVLSGAQFLAV TH_0732|M.thermoresistible__bu RAGYFIPVDG--DGVVTAAGVPVGVTTCWEVIFDRAARESVRNGAEVLAV MSMEG_3860|M.smegmatis_MC2_155 RAGYFVPGTG--TGVVHAAGVPIGITTCWEVIFDRAARESVLNGAQVLAV MAB_2206|M.abscessus_ATCC_1997 RAGYFVPGDG--NGVVTAGGVNIGVATCWEVLFDRALRQSTLNGAEILAV MMAR_3029|M.marinum_M RAGHFVPRPG--SDVVNIAGVPVGVSTCWEVIFDRAPRKAVRNGAQLLAV MUL_5127|M.ulcerans_Agy99 RAGHFVPRPG--SDVVNIAGVPVGVSTCWEVIFDRAPRRAVRNGAQLLAV MLBr_01441|M.leprae_Br4923 RVSHIVPRQSQSSGVVRIAGVPIGVTTCWEVIFDRAARKAVLNGAQLLAA MAV_4605|M.avium_104 ----------------------------------VARRDALLG----LGV * * : . * . Rv2051c|M.tuberculosis_H37Rv PSNNATFNKTMSEQQLAFAKVRAVEHDRYVVVAGTTGISAVIAPDGGELI Mb2077c|M.bovis_AF2122/97 PSNNATFNKTMSEQQLAFAKVRAVEHDRYVVVAGTTGISAVIAPDGGELI Mflv_3117|M.gilvum_PYR-GCK PSNNATFDQAMSEQQLAFGRLRAVEHDRYVVVAGTTGISAVIAPDGHEIV Mvan_3419|M.vanbaalenii_PYR-1 PSNNATFDQAMSEQQLAFGRLRAVEHDRFVVVSGTTGISAVIAPDGREIA TH_0732|M.thermoresistible__bu PTNNATFDEAMSEQHLAFARLRAVEHNRYAVVAGTTGISAVITPDGREVA MSMEG_3860|M.smegmatis_MC2_155 PSNNATFDEAMSAQQLAFGKLRAVEHDRYVVVAGTTGISAVIAPDGHEIS MAB_2206|M.abscessus_ATCC_1997 PSNNALFGSAMSEQQLAISKVRAVEHDREVVVVGTTGISAFVSPDGVDAG MMAR_3029|M.marinum_M PSNNATFNKTMSEQQLAFAKVRAVEHDRYVVVAGTTGISAVIAPDGRELV MUL_5127|M.ulcerans_Agy99 PSNNATFNKTMSEQQLAFAKVRAVEHDRYVVVAGTTGISAVIAPDGRELV MLBr_01441|M.leprae_Br4923 PTNNATFNKTMSEQQLAFAKVRAVEHDRYVVVTGTTGISSVIAPDGSELV MAV_4605|M.avium_104 ADRRSGYPLELLVRAAAAG-WRVVELD--VRYGPRTGGKSKVSG------ . ..: : : : * . *.** : . ** .: :: Rv2051c|M.tuberculosis_H37Rv RTDFFQPAYLDSQVRLKTRLTPATRWGPILQWILVGAAAAV----VLVAM Mb2077c|M.bovis_AF2122/97 RTDFFQPAYLDSQVRLKTRLTPATRWGPILQWILVGAAAAV----VLVAM Mflv_3117|M.gilvum_PYR-GCK RTGWFEPAYLDQQVRLKTSLTPATRFGPYVEGVLIALGVSG----VVGAI Mvan_3419|M.vanbaalenii_PYR-1 RTGWFEPAYLDQQIRLKTRLTPATRFGPYIEAVLVAIGVSG----VLGAM TH_0732|M.thermoresistible__bu RTRFFEPAYLDVQVRLKTQLSPATRYGPVIHGALIAAALAGLGAALAGTV MSMEG_3860|M.smegmatis_MC2_155 RTEWFQPAYLDNQIRLKTDLTPATKWGPIVQAVLVIAGVAV----LLIAI MAB_2206|M.abscessus_ATCC_1997 RTTFFEPAYIDMQVRLHNDLTPATQWGPWVEWALALIAGLAVLASAGLAI MMAR_3029|M.marinum_M RTDFFEPAYLDIQVRLKTRLTPATRWAPILQWLMVGAAGVL----ILVAM MUL_5127|M.ulcerans_Agy99 RTDFFEPAYLDIQVRLKTRLTPATRWAPILQWLMVGAAGVL----ILVAM MLBr_01441|M.leprae_Br4923 RTDFFVPAYLDMQVRLKAKLTPATCWGLTLQWILVGTAGAI----VLAAM MAV_4605|M.avium_104 --------------SLRGSITAILDFWKVIS------------------- *: ::. : : Rv2051c|M.tuberculosis_H37Rv RQNGWFPRPRRSEPKGEN----------------------DDSDAPPGRS Mb2077c|M.bovis_AF2122/97 RQNGWFPRPRRSEPKGEN----------------------DDSDAPPGRS Mflv_3117|M.gilvum_PYR-GCK LHNGSFLPGRLRRRR----------------------------------- Mvan_3419|M.vanbaalenii_PYR-1 LHNGSFVPARFRGRR----------------------------------- TH_0732|M.thermoresistible__bu LQNGRLVPHALRGRRRAKESHDDGPATRPRHHGQSTSESAHSGDHPDLQR MSMEG_3860|M.smegmatis_MC2_155 LHNGRFAPRMLRRRS----------------------------------- MAB_2206|M.abscessus_ATCC_1997 LHNGGLKRPEPEVEP----------------------------------- MMAR_3029|M.marinum_M RHNGWFPRPTRRRSGPAG--------------------EADQSDAPQDEA MUL_5127|M.ulcerans_Agy99 RHNGWFPRPTRRRSGPAG--------------------EADQSDAPQDEA MLBr_01441|M.leprae_Br4923 RHNNGSRSRIVLGLGSSASL-------------KTRVRQANVREALTLRL MAV_4605|M.avium_104 -------------------------------------------------- Rv2051c|M.tuberculosis_H37Rv EASGPPALSESDDELIQPEQGGRHSSGFGRHRATSRSYMTTGQPAPPAPG Mb2077c|M.bovis_AF2122/97 EASGPPALSESDDELIQPEQGGRHSSGFGRHRATSRSYMTTGQPAPPAPG Mflv_3117|M.gilvum_PYR-GCK ---PTSDDGEGAT------------------------------------- Mvan_3419|M.vanbaalenii_PYR-1 ---PTTDDDEGAT------------------------------------- TH_0732|M.thermoresistible__bu TGQSAADRGSGASGLPRGARADRRRRQPRRHR------------------ MSMEG_3860|M.smegmatis_MC2_155 ---ATTVKR----------------------------------------- MAB_2206|M.abscessus_ATCC_1997 ---ASPTKET---------------------------------------- MMAR_3029|M.marinum_M DDSGAASRNESEDDLQTAT--GTPPEAGGHHST----------------- MUL_5127|M.ulcerans_Agy99 DDSGATSRNESEDDLQTAT--GTPPEAGGHHST----------------- MLBr_01441|M.leprae_Br4923 GDRPLIHLSRLVTTLRSIYKGGQKPRYFGRHKGAK--------------- MAV_4605|M.avium_104 -------------------------------------------------- Rv2051c|M.tuberculosis_H37Rv NRPSQRVLVIIPTFNERENLPVIHRRLTQACPAVHVLVVDDSSPDGTGQL Mb2077c|M.bovis_AF2122/97 NRPSQRVLVIIPTFNERENLPVIHRRLTQACPAVHVLVVDDSSPDGTGQL Mflv_3117|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3419|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_0732|M.thermoresistible__bu -------------------------------------------------- MSMEG_3860|M.smegmatis_MC2_155 -------------------------------------------------- MAB_2206|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_3029|M.marinum_M -------------------------------------------------- MUL_5127|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01441|M.leprae_Br4923 -------------------------------------------------- MAV_4605|M.avium_104 -------------------------------------------------- Rv2051c|M.tuberculosis_H37Rv ADELAQADPGRTHVMHRTAKNGLGAAYLAGFAWGLSREYSVLVEMDADGS Mb2077c|M.bovis_AF2122/97 ADELAQADPGRTHVMHRTAKNGLGAAYLAGFAWGLSREYSVLVEMDADGS Mflv_3117|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3419|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_0732|M.thermoresistible__bu -------------------------------------------------- MSMEG_3860|M.smegmatis_MC2_155 -------------------------------------------------- MAB_2206|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_3029|M.marinum_M -------------------------------------------------- MUL_5127|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01441|M.leprae_Br4923 -------------------------------------------------- MAV_4605|M.avium_104 -------------------------------------------------- Rv2051c|M.tuberculosis_H37Rv HAPEQLQRLLDAVDAGADLAIGSRYVAGGTVRNWPWRRLVLSKTANTYSR Mb2077c|M.bovis_AF2122/97 HAPEQLQRLLDAVDAGADLAIGSRYVAGGTVRNWPWRRLVLSKTANTYSR Mflv_3117|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3419|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_0732|M.thermoresistible__bu -------------------------------------------------- MSMEG_3860|M.smegmatis_MC2_155 -------------------------------------------------- MAB_2206|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_3029|M.marinum_M -------------------------------------------------- MUL_5127|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01441|M.leprae_Br4923 -------------------------------------------------- MAV_4605|M.avium_104 -------------------------------------------------- Rv2051c|M.tuberculosis_H37Rv LALGIGIHDITAGYRAYRREALEAIDLDGVDSKGYCFQIDLTWRTVSNGF Mb2077c|M.bovis_AF2122/97 LALGIGIHDITAGYRAYRREALEAIDLDGVDSKGYCFQIDLTWRTVSNGF Mflv_3117|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3419|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_0732|M.thermoresistible__bu -------------------------------------------------- MSMEG_3860|M.smegmatis_MC2_155 -------------------------------------------------- MAB_2206|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_3029|M.marinum_M -------------------------------------------------- MUL_5127|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01441|M.leprae_Br4923 -------------------------------------------------- MAV_4605|M.avium_104 -------------------------------------------------- Rv2051c|M.tuberculosis_H37Rv VVTEVPITFTERELGVSKMSGSNIREALVKVARWGIEGRLSRSDHARARP Mb2077c|M.bovis_AF2122/97 VVTEVPITFTERELGVSKMSGSNIREALVKVARWGIEGRLSRSDHARARP Mflv_3117|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_3419|M.vanbaalenii_PYR-1 -------------------------------------------------- TH_0732|M.thermoresistible__bu -------------------------------------------------- MSMEG_3860|M.smegmatis_MC2_155 -------------------------------------------------- MAB_2206|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_3029|M.marinum_M -------------------------------------------------- MUL_5127|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01441|M.leprae_Br4923 -------------------------------------------------- MAV_4605|M.avium_104 -------------------------------------------------- Rv2051c|M.tuberculosis_H37Rv DIARPGAGGSRVSRADVTE Mb2077c|M.bovis_AF2122/97 DIARPGAGGSRVSRADVTE Mflv_3117|M.gilvum_PYR-GCK ------------------- Mvan_3419|M.vanbaalenii_PYR-1 ------------------- TH_0732|M.thermoresistible__bu ------------------- MSMEG_3860|M.smegmatis_MC2_155 ------------------- MAB_2206|M.abscessus_ATCC_1997 ------------------- MMAR_3029|M.marinum_M ------------------- MUL_5127|M.ulcerans_Agy99 ------------------- MLBr_01441|M.leprae_Br4923 ------------------- MAV_4605|M.avium_104 -------------------