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MAVKMDIDTHHPDVWIVVPAFNEATVIGEVIAQLRSTFGHVVCVDDGSTDGTGDIALRAGAHVVAHPINL GQGAAIQTGVEYARKQPGAQIFATFDADGQHRVKDLAAMVHRLSVGDVDVVIGTRFGRPVGSRPPLLKRI VLQTAARLSPRGRRLGLTDTNNGLRVFNKTVADGLNITMSGMSHATEFVMLIAENHWRVAEEPVEVLYTD YSKSKGQPLLNGVNIIFDGFLRGRIRR
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. ulcerans Agy99 | MUL_4208 | - | - | 100% (237) | glycosyl transferase |
M. ulcerans Agy99 | MUL_0638 | - | 1e-12 | 35.07% (211) | glycosyl transferase - dolichol-P-sugar synthase |
M. ulcerans Agy99 | MUL_4169 | ppm1_2 | 2e-10 | 24.05% (237) | polyprenol-monophosphomannose synthase Ppm1_2 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3655 | - | 1e-118 | 84.65% (241) | transferase |
M. gilvum PYR-GCK | Mflv_3118 | - | 2e-11 | 25.42% (236) | dolichyl-phosphate beta-D-mannosyltransferase |
M. tuberculosis H37Rv | Rv3631 | - | 1e-118 | 84.65% (241) | transferase |
M. leprae Br4923 | MLBr_00207 | - | 1e-106 | 78.48% (237) | putative glycosyltransferase |
M. abscessus ATCC 19977 | MAB_0505c | - | 3e-85 | 65.37% (231) | putative glycosyl transferase |
M. marinum M | MMAR_5131 | - | 1e-133 | 100.00% (233) | glycosyl transferase |
M. avium 104 | MAV_0525 | - | 1e-107 | 85.52% (221) | glycosyl transferase |
M. smegmatis MC2 155 | MSMEG_3859 | - | 5e-13 | 24.79% (238) | glycosyl transferase, group 2 family protein |
M. thermoresistible (build 8) | TH_0733 | - | 6e-10 | 25.00% (212) | Polyprenol-monophosphomannose synthase Ppm1 |
M. vanbaalenii PYR-1 | Mvan_0217 | - | 7e-10 | 27.15% (221) | glycosyl transferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment MSMEG_3859|M.smegmatis_MC2_155 -----------------MSVPGEREQGAGEDPATVRPTQRTLVIIPTYNE TH_0733|M.thermoresistible__bu -------------------------------------------------- Mflv_3118|M.gilvum_PYR-GCK -----------------MSVPG---GVTGREEPAGRPSARTLVIIPTYNE MUL_4208|M.ulcerans_Agy99 ---------------------------MAVKMDIDTHHPDVWIVVPAFNE MMAR_5131|M.marinum_M -------------------------------MDIDTHHPDVWIVVPAFNE Mb3655|M.bovis_AF2122/97 ---------------------------MASKMDTETHYSDVWVVIPAFNE Rv3631|M.tuberculosis_H37Rv ---------------------------MASKMDTETHYSDVWVVIPAFNE MLBr_00207|M.leprae_Br4923 -------------------------------MGIETCYPGVWIVIPAFNE MAV_0525|M.avium_104 -------------------------------------------MIPAFNE MAB_0505c|M.abscessus_ATCC_199 --------------------------------MSNTGNTDVWLVIPAYNE Mvan_0217|M.vanbaalenii_PYR-1 MGELPATGHVGSASHQGQTTTSSPHAQFMLARDGVKVTPSVSLVIPVRNE MSMEG_3859|M.smegmatis_MC2_155 RENLPLIVGRVHHACPQVHILVVDDGSPDGTGALADELALADPDRVHVMH TH_0733|M.thermoresistible__bu -----------------VHVLIVDDGSPDGTGELADELALADPDRVHVMH Mflv_3118|M.gilvum_PYR-GCK RDNLLSIVSRVNDAAPDVHVLIVDDGSPDGTGELADELALGDPDRIHVMH MUL_4208|M.ulcerans_Agy99 ATVIGEVIAQLRSTFG--HVVCVDDGSTDGTGDIALRAGA------HVVA MMAR_5131|M.marinum_M ATVIGEVIAQLRSTFG--HVVCVDDGSTDGTGDIALRAGA------HVVA Mb3655|M.bovis_AF2122/97 AAVIGKVVTDVRSVFD--HVVCVDDGSTDGTGDIARRSGA------HLVR Rv3631|M.tuberculosis_H37Rv AAVIGKVVTDVRSVFD--HVVCVDDGSTDGTGDIARRSGA------HLVR MLBr_00207|M.leprae_Br4923 AAIIGEVVTDVRAVFD--HVVCVDDGSADGTGEIALRAGA------HLVR MAV_0525|M.avium_104 AAVIGEVIADVRSVFD--NVVCVDDGSTDDTGEIARRAGA------HLVR MAB_0505c|M.abscessus_ATCC_199 GPVIADVIAAALGTFP--NIVCVDDGSVDRTAALAHGAGA------HVVR Mvan_0217|M.vanbaalenii_PYR-1 ARNVAWVLEQITEDVD--EIILVDGASTDATLITALRYRP-----DIKVV .:: **..* * * * : MSMEG_3859|M.smegmatis_MC2_155 RTSKAGLGAAYLAGFDWGLRR-GYSVLVEMDADGSHAPEELSRLLDAVDA TH_0733|M.thermoresistible__bu RASKAGLGAAYLAGFRWGLNR-QYSVLVEMDADGSHAPEELHRLLDAVDA Mflv_3118|M.gilvum_PYR-GCK RTSKDGLGAAYLAGFAWGLNR-EYTVLVEMDADGSHAPEDLHRLLAEIDA MUL_4208|M.ulcerans_Agy99 HPINLGQGAAIQTGVEYARKQPGAQIFATFDADGQHRVKDLAAMVHRLSV MMAR_5131|M.marinum_M HPINLGQGAAIQTGVEYARKQPGAQIFATFDADGQHRVKDLAAMVHRLSV Mb3655|M.bovis_AF2122/97 HPINLGQGAAIQTGIEYARKQPGAQVFATFDGDGQHRVKDVAAMVDRLGA Rv3631|M.tuberculosis_H37Rv HPINLGQGAAIQTGIEYARKQPGAQVFATFDGDGQHRVKDVAAMVDRLGA MLBr_00207|M.leprae_Br4923 HPVNLGQGAAIQTGVEYARRQPAAQVFATFDADGQHRVKDLAALVDRLGA MAV_0525|M.avium_104 HPINLGQGAAIQTGVEYARRQPGAQVFATFDADGQHRVKDLAAMVNRLRV MAB_0505c|M.abscessus_ATCC_199 HPVNLGQGAAIQTGVEYARAQPGAQIFVTFDADGQHQVKDVVAMVDRLRL Mvan_0217|M.vanbaalenii_PYR-1 AQDGVGKGSALRTGFFAASGD----IIVMMDADGSMAPQEIRHYVHFLRN * *:* :*. . ::. :*.**. ::: : : MSMEG_3859|M.smegmatis_MC2_155 G-ADLAIGSRYVPGGTVR-----NWPWRRLVLSKTANTYSRFLLGVGIHD TH_0733|M.thermoresistible__bu G-ADLAIGSRYVDGGQVR-----NWPRRRLLLSRTANTYSRLLLGVDIRD Mflv_3118|M.gilvum_PYR-GCK G-ADVVIGSRYVEGGDVR-----NWPRRRMVLSRTANAYSRILLGVDIHD MUL_4208|M.ulcerans_Agy99 GDVDVVIGTRFGRPVG------SRPPLLKRIVLQTAARLSPRGRRLGLTD MMAR_5131|M.marinum_M GDVDVVIGTRFGRPVG------SRPPLLKRIVLQTAARLSPRGRRLGLTD Mb3655|M.bovis_AF2122/97 GDVDVVIGTRFGRPVGKASA--SRPPLMKRIVLQTGARLSRRGRRLGLTD Rv3631|M.tuberculosis_H37Rv GDVDVVIGTRFGRPVGKASA--SRPPLMKRIVLQTGARLSRRGRRLGLTD MLBr_00207|M.leprae_Br4923 HDVDVVIGTRFGRLDGGRLPILKGPPFLKRVVLRTAARLSRRGRRLGLTD MAV_0525|M.avium_104 GDVDVVIGTRFGTRQGAR------PPLVKRMVLQTAARLSRRGRRLGLTD MAB_0505c|M.abscessus_ATCC_199 EPLDIIVGTRFGAGSGPG-----HVPLIKRIVLKTVVLLSPRTRRLNLTD Mvan_0217|M.vanbaalenii_PYR-1 G-YDFVKGSRFIGGGGSL-----DITAFRKLGNRFLLGVFNSLYDSDLTD *. *:*: . : : : .: * MSMEG_3859|M.smegmatis_MC2_155 ITAGYRAYRREVLEKIDLSAVDSKGYCFQIDLTWRAINNGFSVVEVPITF TH_0733|M.thermoresistible__bu ITAGYRAYRREVLEKIDLDAVDSKGYCFQIDLTWRAINHGFKVVEVPITF Mflv_3118|M.gilvum_PYR-GCK ITAGYRAYRREVLEKIDLAAVDSKGYGFQVDLTWRSINAGFTVVEVPITF MUL_4208|M.ulcerans_Agy99 TNNGLRVFNKTVADGLNITMS---GMSHATEFVMLIAENHWRVAEEPVEV MMAR_5131|M.marinum_M TNNGLRVFNKTVADGLNITMS---GMSHATEFVMLIAENHWRVAEEPVEV Mb3655|M.bovis_AF2122/97 TNNGLRVFNKTVADGLNITMS---GMSHATEFIMLIAENHWRVAEEPVEV Rv3631|M.tuberculosis_H37Rv TNNGLRVFNKTVADGLNITMS---GMSHATEFIMLIAENHWRVAEEPVEV MLBr_00207|M.leprae_Br4923 TNNGLRVFNKKVADGLDITMT---GMSHANEFVMLIADNHWRVDEVPVEV MAV_0525|M.avium_104 TNNGLRVFNKKVADGLDITMS---GMSHANEFVMLIDENHWRVVEEPIEV MAB_0505c|M.abscessus_ATCC_199 AHNGLRVFNRTVANGLNITMN---GMGHASEFIAMISENHWRVAEQPVDI Mvan_0217|M.vanbaalenii_PYR-1 LCYGFCAFHRRYLELLELSAT---GFEIEAEMTVRAMQAGLRIAEVPSLE * .:.: : ::: * :: : : * * MSMEG_3859|M.smegmatis_MC2_155 TERELGVSKM----SGSNIREAMFKVAEWGIRGRLDRARGVVR------- TH_0733|M.thermoresistible__bu TERELGQSKM----SGSNIREAIFKVAEWGIRGRLDRARGIVR------- Mflv_3118|M.gilvum_PYR-GCK TEREHGVSKM----DGSTIREAIIKVAQWGMRARIDRARGNTP------- MUL_4208|M.ulcerans_Agy99 LYTDYSKS------KGQPLLNGVNIIFDGFLRGRIRR------------- MMAR_5131|M.marinum_M LYTDYSKS------KGQPLLNGVNIIFDGFLRGRIRR------------- Mb3655|M.bovis_AF2122/97 LYTEYSKS------KGQPLLNGVNIIFDGFLRGRMPR------------- Rv3631|M.tuberculosis_H37Rv LYTEYSKS------KGQPLLNGVNIIFDGFLRGRMPR------------- MLBr_00207|M.leprae_Br4923 LYTEYSKS------KGQPLLNGVNIIFDGFLRGRMPK------------- MAV_0525|M.avium_104 LYTEYSRS------KGQPLLNGVNIIFDGFLRGRIPR------------- MAB_0505c|M.abscessus_ATCC_199 LYTEYSMA------KGQSLINGVNIMFDTAFRRRLP-------------- Mvan_0217|M.vanbaalenii_PYR-1 MPRRSGKSNLRAVRDGTRVLRTVLHGHRSGVSGHLLEVLSQRRGPAAAAA . : .* : . : . :: MSMEG_3859|M.smegmatis_MC2_155 --- TH_0733|M.thermoresistible__bu --- Mflv_3118|M.gilvum_PYR-GCK --- MUL_4208|M.ulcerans_Agy99 --- MMAR_5131|M.marinum_M --- Mb3655|M.bovis_AF2122/97 --- Rv3631|M.tuberculosis_H37Rv --- MLBr_00207|M.leprae_Br4923 --- MAV_0525|M.avium_104 --- MAB_0505c|M.abscessus_ATCC_199 --- Mvan_0217|M.vanbaalenii_PYR-1 EAC