For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_0733 | - | 100% (216) | Polyprenol-monophosphomannose synthase Ppm1 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2077c | ppm1 | 5e-98 | 81.43% (210) | polyprenol-monophosphomannose synthase Ppm1 |
| M. gilvum PYR-GCK | Mflv_3118 | - | 1e-102 | 83.49% (212) | dolichyl-phosphate beta-D-mannosyltransferase |
| M. tuberculosis H37Rv | Rv2051c | ppm1 | 5e-98 | 81.43% (210) | polyprenol-monophosphomannose synthase Ppm1 |
| M. leprae Br4923 | MLBr_01440 | - | 8e-97 | 78.67% (211) | putative glycosyl transferase |
| M. abscessus ATCC 19977 | MAB_2207 | - | 3e-96 | 79.53% (215) | polyprenol phosphate mannosyl transferase 1 |
| M. marinum M | MMAR_3028 | ppm1B | 2e-97 | 78.77% (212) | polyprenol-monophosphomannose synthase, Ppm1B |
| M. avium 104 | MAV_0525 | - | 3e-11 | 27.57% (214) | glycosyl transferase |
| M. smegmatis MC2 155 | MSMEG_3859 | - | 1e-109 | 89.77% (215) | glycosyl transferase, group 2 family protein |
| M. ulcerans Agy99 | MUL_2269 | ppm1B | 4e-97 | 78.30% (212) | C-term polyprenol-monophosphomannose synthase Ppm1B |
| M. vanbaalenii PYR-1 | Mvan_3418 | - | 2e-98 | 80.00% (215) | dolichyl-phosphate beta-D-mannosyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3118|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3418|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0733|M.thermoresistible__bu --------------------------------------------------
MSMEG_3859|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2207|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_3028|M.marinum_M --------------------------------------------------
MUL_2269|M.ulcerans_Agy99 --------------------------------------------------
Mb2077c|M.bovis_AF2122/97 MKLGAWVAAQLPTTRTAVRTRLTRLVVSIVAGLLLYASFPPRNCWWAAVV
Rv2051c|M.tuberculosis_H37Rv MKLGAWVAAQLPTTRTAVRTRLTRLVVSIVAGLLLYASFPPRNCWWAAVV
MLBr_01440|M.leprae_Br4923 --------------------------------------------------
MAV_0525|M.avium_104 --------------------------------------------------
Mflv_3118|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3418|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0733|M.thermoresistible__bu --------------------------------------------------
MSMEG_3859|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2207|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_3028|M.marinum_M --------------------------------------------------
MUL_2269|M.ulcerans_Agy99 --------------------------------------------------
Mb2077c|M.bovis_AF2122/97 ALALLAWVLTHRATTPVGGLGYGLLFGLVFYVSLLPWIGELVGPGPWLAL
Rv2051c|M.tuberculosis_H37Rv ALALLAWVLTHRATTPVGGLGYGLLFGLVFYVSLLPWIGELVGPGPWLAL
MLBr_01440|M.leprae_Br4923 --------------------------------------------------
MAV_0525|M.avium_104 --------------------------------------------------
Mflv_3118|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3418|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0733|M.thermoresistible__bu --------------------------------------------------
MSMEG_3859|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2207|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_3028|M.marinum_M --------------------------------------------------
MUL_2269|M.ulcerans_Agy99 --------------------------------------------------
Mb2077c|M.bovis_AF2122/97 ATTCALFPGIFGLFAVVVRLLPGWPIWFAVGWAAQEWLKSILPFGGFPWG
Rv2051c|M.tuberculosis_H37Rv ATTCALFPGIFGLFAVVVRLLPGWPIWFAVGWAAQEWLKSILPFGGFPWG
MLBr_01440|M.leprae_Br4923 --------------------------------------------------
MAV_0525|M.avium_104 --------------------------------------------------
Mflv_3118|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3418|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0733|M.thermoresistible__bu --------------------------------------------------
MSMEG_3859|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2207|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_3028|M.marinum_M --------------------------------------------------
MUL_2269|M.ulcerans_Agy99 --------------------------------------------------
Mb2077c|M.bovis_AF2122/97 SVAFGQAEGPLLPLVQLGGVALLSTGVALVGCGLTAIALEIEKWWRTGGQ
Rv2051c|M.tuberculosis_H37Rv SVAFGQAEGPLLPLVQLGGVALLSTGVALVGCGLTAIALEIEKWWRTGGQ
MLBr_01440|M.leprae_Br4923 --------------------------------------------------
MAV_0525|M.avium_104 --------------------------------------------------
Mflv_3118|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3418|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0733|M.thermoresistible__bu --------------------------------------------------
MSMEG_3859|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2207|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_3028|M.marinum_M --------------------------------------------------
MUL_2269|M.ulcerans_Agy99 --------------------------------------------------
Mb2077c|M.bovis_AF2122/97 GDAPPAVVLPAACICLVLFAAIVVWPQVRHAGSGSGGEPTVTVAVVQGNV
Rv2051c|M.tuberculosis_H37Rv GDAPPAVVLPAACICLVLFAAIVVWPQVRHAGSGSGGEPTVTVAVVQGNV
MLBr_01440|M.leprae_Br4923 --------------------------------------------------
MAV_0525|M.avium_104 --------------------------------------------------
Mflv_3118|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3418|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0733|M.thermoresistible__bu --------------------------------------------------
MSMEG_3859|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2207|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_3028|M.marinum_M --------------------------------------------------
MUL_2269|M.ulcerans_Agy99 --------------------------------------------------
Mb2077c|M.bovis_AF2122/97 PRLGLDFNAQRRAVLDNHVEETLRLAADVHAGLAQQPQFVIWPENSSDID
Rv2051c|M.tuberculosis_H37Rv PRLGLDFNAQRRAVLDNHVEETLRLAADVHAGLAQQPQFVIWPENSSDID
MLBr_01440|M.leprae_Br4923 --------------------------------------------------
MAV_0525|M.avium_104 --------------------------------------------------
Mflv_3118|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3418|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0733|M.thermoresistible__bu --------------------------------------------------
MSMEG_3859|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2207|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_3028|M.marinum_M --------------------------------------------------
MUL_2269|M.ulcerans_Agy99 --------------------------------------------------
Mb2077c|M.bovis_AF2122/97 PFVNPDAGQRISAAAEAIGAPILIGTLMDVPGRPRENPEWTNTAIVWNPG
Rv2051c|M.tuberculosis_H37Rv PFVNPDAGQRISAAAEAIGAPILIGTLMDVPGRPRENPEWTNTAIVWNPG
MLBr_01440|M.leprae_Br4923 --------------------------------------------------
MAV_0525|M.avium_104 --------------------------------------------------
Mflv_3118|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3418|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0733|M.thermoresistible__bu --------------------------------------------------
MSMEG_3859|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2207|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_3028|M.marinum_M --------------------------------------------------
MUL_2269|M.ulcerans_Agy99 --------------------------------------------------
Mb2077c|M.bovis_AF2122/97 TGPADRHDKAIVQPFGEYLPMPWLFRHLSGYADRAGHFVPGNGTGVVRIA
Rv2051c|M.tuberculosis_H37Rv TGPADRHDKAIVQPFGEYLPMPWLFRHLSGYADRAGHFVPGNGTGVVRIA
MLBr_01440|M.leprae_Br4923 --------------------------------------------------
MAV_0525|M.avium_104 --------------------------------------------------
Mflv_3118|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3418|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0733|M.thermoresistible__bu --------------------------------------------------
MSMEG_3859|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2207|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_3028|M.marinum_M --------------------------------------------------
MUL_2269|M.ulcerans_Agy99 --------------------------------------------------
Mb2077c|M.bovis_AF2122/97 GVPVGVATCWEVIFDRAPRKSILGGAQLLTVPSNNATFNKTMSEQQLAFA
Rv2051c|M.tuberculosis_H37Rv GVPVGVATCWEVIFDRAPRKSILGGAQLLTVPSNNATFNKTMSEQQLAFA
MLBr_01440|M.leprae_Br4923 --------------------------------------------------
MAV_0525|M.avium_104 --------------------------------------------------
Mflv_3118|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3418|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0733|M.thermoresistible__bu --------------------------------------------------
MSMEG_3859|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2207|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_3028|M.marinum_M --------------------------------------------------
MUL_2269|M.ulcerans_Agy99 --------------------------------------------------
Mb2077c|M.bovis_AF2122/97 KVRAVEHDRYVVVAGTTGISAVIAPDGGELIRTDFFQPAYLDSQVRLKTR
Rv2051c|M.tuberculosis_H37Rv KVRAVEHDRYVVVAGTTGISAVIAPDGGELIRTDFFQPAYLDSQVRLKTR
MLBr_01440|M.leprae_Br4923 --------------------------------------------------
MAV_0525|M.avium_104 --------------------------------------------------
Mflv_3118|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3418|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_0733|M.thermoresistible__bu --------------------------------------------------
MSMEG_3859|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2207|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_3028|M.marinum_M --------------------------------------------------
MUL_2269|M.ulcerans_Agy99 --------------------------------------------------
Mb2077c|M.bovis_AF2122/97 LTPATRWGPILQWILVGAAAAVVLVAMRQNGWFPRPRRSEPKGENDDSDA
Rv2051c|M.tuberculosis_H37Rv LTPATRWGPILQWILVGAAAAVVLVAMRQNGWFPRPRRSEPKGENDDSDA
MLBr_01440|M.leprae_Br4923 --------------------------------------------------
MAV_0525|M.avium_104 --------------------------------------------------
Mflv_3118|M.gilvum_PYR-GCK -----------------------------------------MSVPGGVTG
Mvan_3418|M.vanbaalenii_PYR-1 -----------------------------------------MSVPGGMTD
TH_0733|M.thermoresistible__bu --------------------------------------------------
MSMEG_3859|M.smegmatis_MC2_155 --------------------------------------MSVPGEREQGAG
MAB_2207|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_3028|M.marinum_M -------------------------------------------MTTGQPA
MUL_2269|M.ulcerans_Agy99 -------------------------------------------MTTGQPA
Mb2077c|M.bovis_AF2122/97 PPGRSEASGPPALSESDDELIQPEQGGRHSSGFGRHRATSRSYMTTGQPA
Rv2051c|M.tuberculosis_H37Rv PPGRSEASGPPALSESDDELIQPEQGGRHSSGFGRHRATSRSYMTTGQPA
MLBr_01440|M.leprae_Br4923 -------------------------------------------MITGQPA
MAV_0525|M.avium_104 --------------------------------------------------
Mflv_3118|M.gilvum_PYR-GCK REEPAGRPSARTLVIIPTYNERDNLLSIVSRVNDAAPDVHVLIVDDGSPD
Mvan_3418|M.vanbaalenii_PYR-1 GPGPGTRPSDRTLVIIPTYNERQNLPLIVGRVHQARPDVDILIVDDDSPD
TH_0733|M.thermoresistible__bu --------------------------------------VHVLIVDDGSPD
MSMEG_3859|M.smegmatis_MC2_155 EDPATVRPTQRTLVIIPTYNERENLPLIVGRVHHACPQVHILVVDDGSPD
MAB_2207|M.abscessus_ATCC_1997 MDPVTERPSARTLVIIPTYNERENLPLILGRLHKAQPDVHVLIVDDGSPD
MMAR_3028|M.marinum_M PQSPGPRPSERTLVIIPTYNERENLPLIHRRVVDACPHVHVLIVDDNSPD
MUL_2269|M.ulcerans_Agy99 PQSPGPRPSERTLVIIPTYNERENLPLIHRRVVDACPHVHVLIVDDNSPD
Mb2077c|M.bovis_AF2122/97 PPAPGNRPSQRVLVIIPTFNERENLPVIHRRLTQACPAVHVLVVDDSSPD
Rv2051c|M.tuberculosis_H37Rv PPAPGNRPSQRVLVIIPTFNERENLPVIHRRLTQACPAVHVLVVDDSSPD
MLBr_01440|M.leprae_Br4923 RKISGNRPSQCVLVIIPTFNELENLPVTHGRLKDAYPEIHVLIVDDGSPD
MAV_0525|M.avium_104 --------------MIPAFNEAAVIGEVIADVRSVFD--NVVCVDDGSTD
.:: ***.*.*
Mflv_3118|M.gilvum_PYR-GCK GTGELADELALGDPDRIHVMHRTSKDGLGAAYLAGFAWGLNR-EYTVLVE
Mvan_3418|M.vanbaalenii_PYR-1 GTGQLADELSVADPDRIHVMHRTAKEGLGAAYLAGFAWGLGR-QYTVLVE
TH_0733|M.thermoresistible__bu GTGELADELALADPDRVHVMHRASKAGLGAAYLAGFRWGLNR-QYSVLVE
MSMEG_3859|M.smegmatis_MC2_155 GTGALADELALADPDRVHVMHRTSKAGLGAAYLAGFDWGLRR-GYSVLVE
MAB_2207|M.abscessus_ATCC_1997 GTGELADEAALADPDRVHVMHRKEKGGLGAAYIAGFGWGLAR-QYSVLVE
MMAR_3028|M.marinum_M GTGRLADELVAADPDRIHVLHRTAKNGLGAAYLEGFAWGLSR-GYSVLVE
MUL_2269|M.ulcerans_Agy99 GTGRLADELVAADPDRIHVLHRTAKNGLGAAYLEGFAWGLSR-GYSVLVE
Mb2077c|M.bovis_AF2122/97 GTGQLADELAQADPGRTHVMHRTAKNGLGAAYLAGFAWGLSR-EYSVLVE
Rv2051c|M.tuberculosis_H37Rv GTGQLADELAQADPGRTHVMHRTAKNGLGAAYLAGFAWGLSR-EYSVLVE
MLBr_01440|M.leprae_Br4923 GTGELADELAQVDPGCTHVMHRTTKDGLGTAYLAGFAWGMSR-DYSVLVE
MAV_0525|M.avium_104 DTGEIARRAG------AHLVRHPINLGQGAAIQTGVEYARRQPGAQVFAT
.** :* . *:::: : * *:* *. :. : *:.
Mflv_3118|M.gilvum_PYR-GCK MDADGSHAPEDLHRLLAEIDAG-ADVVIGSRYVEGGDVRNWPRRRMVLSR
Mvan_3418|M.vanbaalenii_PYR-1 MDADGSHPPEQLARLLDAVDAG-ADVVIGSRYVSGGEVVNWPRRRLVLSR
TH_0733|M.thermoresistible__bu MDADGSHAPEELHRLLDAVDAG-ADLAIGSRYVDGGQVRNWPRRRLLLSR
MSMEG_3859|M.smegmatis_MC2_155 MDADGSHAPEELSRLLDAVDAG-ADLAIGSRYVPGGTVRNWPWRRLVLSK
MAB_2207|M.abscessus_ATCC_1997 MDADGSHAPEQLSRLLDAVDAG-ADLAIGSRYVPGGTVVNWPWRRLVLSR
MMAR_3028|M.marinum_M MDADGSHAPEQLHRLLDAVDAG-ADLSIGSRYVPGGTVRNWPWRRLALSK
MUL_2269|M.ulcerans_Agy99 MDADGSHAPEQLHRLLDAVDAG-ADLSIGSRYVPGGTVRNWPWQRLALSK
Mb2077c|M.bovis_AF2122/97 MDADGSHAPEQLQRLLDAVDAG-ADLAIGSRYVAGGTVRNWPWRRLVLSK
Rv2051c|M.tuberculosis_H37Rv MDADGSHAPEQLQRLLDAVDAG-ADLAIGSRYVAGGTVRNWPWRRLVLSK
MLBr_01440|M.leprae_Br4923 MDADGSHAPEQLHRLLGAVDAG-ADLAIGSRYVNGGTVRNWPWQRLALSK
MAV_0525|M.avium_104 FDADGQHRVKDLAAMVNRLRVGDVDVVIGTRFGTRQGARPPLVKRMVLQT
:****.* ::* :: : .* .*: **:*: . :*: *.
Mflv_3118|M.gilvum_PYR-GCK TANAYSRILLGVDIHDITAGYRAYRREVLEKIDLAAVDSKGYGFQVDLTW
Mvan_3418|M.vanbaalenii_PYR-1 TANGYSRILLGVDIHDITAGYRAYRREVLEKIDLAAVDTKGYGFQVDLTW
TH_0733|M.thermoresistible__bu TANTYSRLLLGVDIRDITAGYRAYRREVLEKIDLDAVDSKGYCFQIDLTW
MSMEG_3859|M.smegmatis_MC2_155 TANTYSRFLLGVGIHDITAGYRAYRREVLEKIDLSAVDSKGYCFQIDLTW
MAB_2207|M.abscessus_ATCC_1997 SANVYARLVLGVKPHDITAGYRAYRREVLEKLDLGAVESHGYCFQIDLTL
MMAR_3028|M.marinum_M TANTYSRLALGIGVHDITAGYRAYRREVLEKIDLASVDSKGYCFQIEMTW
MUL_2269|M.ulcerans_Agy99 TANTYSRLALGIGVHDITAGYRAYRREVLEKIDLASVDSKGYCFQIEMTW
Mb2077c|M.bovis_AF2122/97 TANTYSRLALGIGIHDITAGYRAYRREALEAIDLDGVDSKGYCFQIDLTW
Rv2051c|M.tuberculosis_H37Rv TANTYSRLALGIGIHDITAGYRAYRREALEAIDLDGVDSKGYCFQIDLTW
MLBr_01440|M.leprae_Br4923 TANKYSRLALGIDVHDITAGYRAYRREVLEAIDLDSVASKGYCFQIDLTW
MAV_0525|M.avium_104 AAR-LSRRGRRLGLTDTNNGLRVFNKKVADGLDITMS---GMSHANEFVM
:*. :* : * . * *.:.::. : :*: * . ::.
Mflv_3118|M.gilvum_PYR-GCK RSINAGFTVVEVPITFTEREHGVSKMDGSTIREAIIKVAQWGMRARIDRA
Mvan_3418|M.vanbaalenii_PYR-1 RSINAGFTVIEVPITFTEREHGVSKMDGSTIREAIIKVAQWGLRARLDRA
TH_0733|M.thermoresistible__bu RAINHGFKVVEVPITFTERELGQSKMSGSNIREAIFKVAEWGIRGRLDRA
MSMEG_3859|M.smegmatis_MC2_155 RAINNGFSVVEVPITFTERELGVSKMSGSNIREAMFKVAEWGIRGRLDRA
MAB_2207|M.abscessus_ATCC_1997 RTIAHGFEVAEVPITFTERAIGESKMSGSIINEALVKVTKWGVQSRLDRA
MMAR_3028|M.marinum_M RSVNSGFVVVEVPITFTEREIGVSKMSGSNIREALFKVTRWGVKGRFAGS
MUL_2269|M.ulcerans_Agy99 RSVNSGFVVVEVPITFTEREIGVSKMSGSNIREALFKVTRWGVKGRFAGS
Mb2077c|M.bovis_AF2122/97 RTVSNGFVVTEVPITFTERELGVSKMSGSNIREALVKVARWGIEGRLSRS
Rv2051c|M.tuberculosis_H37Rv RTVSNGFVVTEVPITFTERELGVSKMSGSNIREALVKVARWGIEGRLSRS
MLBr_01440|M.leprae_Br4923 RTVNNGFVIIEVPITFTEREFGLSKMSGSNIREALVKVTRWGIDGRIQRA
MAV_0525|M.avium_104 LIDENHWRVVEEPIEVLYTEYSRS--KGQPLLNGVNIIFDGFLRGRIPR-
: : * ** . . * .*. : :.: : : .*:
Mflv_3118|M.gilvum_PYR-GCK RG------NTP---------------
Mvan_3418|M.vanbaalenii_PYR-1 RG------TTR---------------
TH_0733|M.thermoresistible__bu RG------IVR---------------
MSMEG_3859|M.smegmatis_MC2_155 RG------VVR---------------
MAB_2207|M.abscessus_ATCC_1997 RG------VNR---------------
MMAR_3028|M.marinum_M EGGGDRAHTHDHS-------------
MUL_2269|M.ulcerans_Agy99 EGGGDRAHTHDHS-------------
Mb2077c|M.bovis_AF2122/97 DHARARPDIARPGAGGSRVSRADVTE
Rv2051c|M.tuberculosis_H37Rv DHARARPDIARPGAGGSRVSRADVTE
MLBr_01440|M.leprae_Br4923 RTGRAYNSVSRGGGTGSSPSAP----
MAV_0525|M.avium_104 --------------------------