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LTLAVALILLAVVLGFAVARPRGWPEAAAAVPAAVILLAIGAISPQQAMAQVSGLARVVAFLGAVLVLAK LCDDEGLFEAAGAAMARASAESHRLLRQVFAVSAAITAALCLDATVVLLTPVVLATVRRLRTPVRPYAYA TAHLANAASLLLPVSNLTNLLAYHGAGISFTKFTLLMALPWLSAVAAVYVVFRWFFARDLRVVPDRQQLK PAPRLPMFVLVVVALTLGGFAVAESVGLAPTWAALAGAAVLALRSLRRGHTSVLRIARAVNVSFLVFVLA LGVVVHAVMLNGMAARMSAVLPTGSGLPALLGIAALAAVLANVVNNLPATLVLVPLVAAGGPAAVLAVLL GVNIGPNLTYAGSLSNLLWRGVLRRHNVDASVGEYTRLGLCTVPAALAMAVLALWASAQVLGI
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3578 | arsB2 | - | 100% (413) | POSSIBLE ARSENICAL PUMP INTEGRAL MEMBRANE PROTEIN ARSB2 |
| M. tuberculosis H37Rv | Rv2685 | arsB1 | 3e-21 | 23.90% (431) | arsenic-transport integral membrane protein ArsB1 |
| M. tuberculosis H37Rv | Rv2684 | arsA | 3e-21 | 25.53% (376) | arsenic-transport integral membrane protein ArsA |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3609 | arsB2 | 0.0 | 99.76% (413) | arsenical PUMP integral membrane protein ArsB2 |
| M. gilvum PYR-GCK | Mflv_1448 | - | 1e-124 | 58.45% (414) | arsenical pump membrane protein |
| M. leprae Br4923 | MLBr_01036 | - | 1e-18 | 23.58% (424) | putative membrane transport protein |
| M. abscessus ATCC 19977 | MAB_3634c | - | 7e-05 | 26.58% (237) | putative gluconate permease |
| M. marinum M | MMAR_5078 | arsB2 | 0.0 | 80.39% (413) | arsenical pump integral membrane protein ArsB2 |
| M. avium 104 | MAV_0577 | - | 1e-169 | 75.24% (412) | arsenical pump membrane protein |
| M. smegmatis MC2 155 | MSMEG_6072 | - | 1e-133 | 61.26% (413) | citrate transporter |
| M. thermoresistible (build 8) | TH_3461 | - | 1e-123 | 58.21% (414) | PUTATIVE putative Arsenical pump membrane protein |
| M. ulcerans Agy99 | MUL_4154 | arsB2 | 1e-177 | 78.69% (413) | arsenical pump integral membrane protein ArsB2 |
| M. vanbaalenii PYR-1 | Mvan_5336 | - | 1e-132 | 60.87% (414) | arsenical pump membrane protein |
CLUSTAL 2.0.9 multiple sequence alignment
Rv3578|M.tuberculosis_H37Rv -------------------MTLAVALILLAVVLGFAVARPRGWPEAAAAV
Mb3609|M.bovis_AF2122/97 -------------------MTLAVALILLAVVLGFAVARPRGWPEAAAAV
MMAR_5078|M.marinum_M -------------------MTLTVALLLLAVVLAFAVARPRGWPEAVAAV
MUL_4154|M.ulcerans_Agy99 -------------------MTLTVALLLLAVVLAFAVARPRGWPEAVAAV
MAV_0577|M.avium_104 -------------------MALTVALVLLAVVLGFAVARPRGWPEAVAAV
Mflv_1448|M.gilvum_PYR-GCK -------------------MALTLSVAALAAVLACALLRPR--LQAIVAG
Mvan_5336|M.vanbaalenii_PYR-1 -------------------MELILSVAALASVLAFALLRPHRWPEAVIAV
TH_3461|M.thermoresistible__bu -------------------MAVTVASAALIAVLVSALTRPRGWPEAVVAV
MSMEG_6072|M.smegmatis_MC2_155 -----MAAQRPLDRDRERALALTLALIALIVVLTFAMVRPNGWPEAVAAV
MLBr_01036|M.leprae_Br4923 ----------------------MSVIAITVFIVTYALIASDRVNKTLAAL
MAB_3634c|M.abscessus_ATCC_199 MNAGLVLLAEQANVAHTTSEVRLLAAVLLSIGAIILLITRLRLHPFLALL
:
Rv3578|M.tuberculosis_H37Rv PAAVILLAIGAISPQQAMAQVSG-----LARVVAFLGAVLVLAKLCDDEG
Mb3609|M.bovis_AF2122/97 PAAVILLAIGAISPQQAMAQVSG-----LARVVAFLGAVLVLAKLCDDEG
MMAR_5078|M.marinum_M PAAGILIAMGAISPQQAAAQVSG-----LAGVVAFLGAVLVLAKLCDDEG
MUL_4154|M.ulcerans_Agy99 PAAGILIAMGAISPQQAAAQVSG-----LAGMVAFLGAVLVLAKLCDDEG
MAV_0577|M.avium_104 PAALLLVGVGAIPVAAAEQQIAD-----LSGVVAFLGAVLVLAKLCDDEG
Mflv_1448|M.gilvum_PYR-GCK LAAALVIVAGATTWRAAVGEISE-----LAPVVAFLAAVLVLARLCDDEG
Mvan_5336|M.vanbaalenii_PYR-1 PAAALVIASGAISWDDALAEVGR-----LAPVVGFLAAVLVLARLCDDVG
TH_3461|M.thermoresistible__bu PAAALVVLTGAIALPDALAVADR-----LLPVVGFLAAVLVLARLCDDEG
MSMEG_6072|M.smegmatis_MC2_155 PAAVLLIALGAISVHDAVDEAGR-----LLPVVGFLAAVLVLAHLCDDEG
MLBr_01036|M.leprae_Br4923 TGAAIVVTLPIINSEDVFYSHETGI---DWEVIFLLLSMMIIVSVLRQTG
MAB_3634c|M.abscessus_ATCC_199 LGSGTLAAAASVPFDKLLGSFVTGFGSTIAGVGLLIGLGAMLGRLLADSG
.: : : :: :: : : *
Rv3578|M.tuberculosis_H37Rv LFEAAGAAMARASAE-SHRLLRQVFAVSAAITAALCLDATVVLLTPVVLA
Mb3609|M.bovis_AF2122/97 LFEAAGAAMARASAE-SHRLLRQVFAVSAAITAALCLDATVVLLTPVVLA
MMAR_5078|M.marinum_M LFEAAGAAMARSSRS-SHGLLGQVFVVAALITAALSLDATVVLLTPVVLA
MUL_4154|M.ulcerans_Agy99 LSEAAGAAMARSSPS-SHGLLGQVFVVAALITAALSLDATVVLLTPVVLA
MAV_0577|M.avium_104 LFEAAGAAIARGRVG-SAGMLRRVFVIASAITAVLSLDAAVVLLTPVVLA
Mflv_1448|M.gilvum_PYR-GCK LFRAAGTLMARATSGGQSRLLTTVFAISAAVTAILSLDATVILLTPVVLA
Mvan_5336|M.vanbaalenii_PYR-1 LFHTAGVMMARATSGGQIRLLASVFAIAAGVTAILSLDATVVLLTPVVLA
TH_3461|M.thermoresistible__bu LFRAAGAAMARVSSGNPVRLLAMVFVVAAATTAILSLDATAVLLTPVVLA
MSMEG_6072|M.smegmatis_MC2_155 LFHAAGTLMARASRGHPRKLLLRVFVIGATTTAVLSLDATVVLLTPVVLA
MLBr_01036|M.leprae_Br4923 VFEYVAIWTAKRSHGSPLRILLLLVLVMALGSALLDNVTTVLLIAPVTLL
MAB_3634c|M.abscessus_ATCC_199 GANIVADAVLTRSSP--RLLPWAVASIAAVLGLPLFFEVGVVLLIPIVLL
. .. : : : : * . .:*: *:.*
Rv3578|M.tuberculosis_H37Rv TVRRLRTPVRPYAYATAHLANAASLLLPVSN--LTNLLAYHGAGISFTKF
Mb3609|M.bovis_AF2122/97 TVRRLRTPVRPYAYATAHLANAASLLLPVSN--LTNLLAYHGAGISFTKF
MMAR_5078|M.marinum_M TVRRLRTPVRPYAYATAHLANAASLLLPVSN--LTNLLAYRGADISFTKF
MUL_4154|M.ulcerans_Agy99 TVRRLRTPVRPYAYATAHLANAASPLLPVSN--LTNLLAYRGADISFTKF
MAV_0577|M.avium_104 AVRRQRTAVRPYAYATAHLANGASLLLPVSN--LTNLLAFHTAQLSFTRF
Mflv_1448|M.gilvum_PYR-GCK TARALAVPARPHAYATAHLANSASLLLPVSN--LTNLLAFSAAGLSFLHF
Mvan_5336|M.vanbaalenii_PYR-1 TARTLAVPPRPHAYATAHLANSASLLLPVSN--LTNLLAFGAAGLSFLHF
TH_3461|M.thermoresistible__bu TARRLGVAPRPHAYATAHLANSASLLLPVSN--LTNLLAFGVCGLSFTRF
MSMEG_6072|M.smegmatis_MC2_155 TARTLAIAPRPHAYASAHLANSASLLFPVSN--LTNLLAFTVAGLSFVEF
MLBr_01036|M.leprae_Br4923 VCERLTINAAPFLMAEVFASNIGGAATLVGD--PPNIIIASRAGFSFNDF
MAB_3634c|M.abscessus_ATCC_199 VARRGNVPLLRVGIPALAGLSVLHGLVPPHPGPLVAVDALKADLGVTLAF
. . . . : *
Rv3578|M.tuberculosis_H37Rv TLLMALPWLSAVAAVYVVFRWFFARDLRV----VPDR-QQLKPAPR----
Mb3609|M.bovis_AF2122/97 TLLMALPWLSAVAAVYVVFRWFFARDLRV----VPDR-QQLKPAPR----
MMAR_5078|M.marinum_M TLVMTLPWLLAIAAVYVIFRWFFARDLVA----EPNR-EHVGPPPR----
MUL_4154|M.ulcerans_Agy99 TLVMTLPWLLAIAAVYVILCWFFARDLVA----EPNR-EHVGPPPR----
MAV_0577|M.avium_104 TLLMAAPWLAAVATLYAVFRGFFAKDLRV----QPDP-AALGAPPR----
Mflv_1448|M.gilvum_PYR-GCK AAAMTLPWIAAIVVEFLLLRWLFAKDLAT----EPQR-AVSVEPLD----
Mvan_5336|M.vanbaalenii_PYR-1 AAAMSLPWLAAIAVEFVLLRWFFAKDLAV----EPRR-AAVTEPVE----
TH_3461|M.thermoresistible__bu TALMTLPWLAAIACEFVLLRRLFRADLSP----APSTGDRPAEPVG----
MSMEG_6072|M.smegmatis_MC2_155 SAYMAIPWLAAVAVEFALLSWLFSAELRP----RPVP-ETAPPPPE----
MLBr_01036|M.leprae_Br4923 LIHLTPIVIIVTVVLSALLPRLFRGAFAV----DPERVADIMSLNEREAI
MAB_3634c|M.abscessus_ATCC_199 GLVAAVPTLIVAGPLYARIAERWVGPLDIPTATAPEAERTGPAPSVVAVL
: : . : : : *
Rv3578|M.tuberculosis_H37Rv ----LPMFVLVVVALTLGGFAVAESVG------LAPTWAALAGAAVLALR
Mb3609|M.bovis_AF2122/97 ----LPMFVLVVVALTLGGFAVAESVG------LAPTWAALAGAAVLALR
MMAR_5078|M.marinum_M ----PPVFVLVVVALTLVGFATAESLG------VAPAWAALAGASVLAVR
MUL_4154|M.ulcerans_Agy99 ----PPVFVLVVVALTLVGFATAESLG------VAPAWAALAGASVLAVR
MAV_0577|M.avium_104 ----PPVFVLVVVALTLAGFAVAQSVG------IAPAWVALCGASVLAVR
Mflv_1448|M.gilvum_PYR-GCK ----VPKFTLAVVVLTLAGFAVTSLLG------FSPAWAALAGALVLGVR
Mvan_5336|M.vanbaalenii_PYR-1 ----VPVFALVVLGLTLLGFAVTSLLG------LSPAWAALAGALVLGVR
TH_3461|M.thermoresistible__bu ----VPVFVLTVLGLTLTGFAVTSWLG------IAPAWAALAGALVLGVH
MSMEG_6072|M.smegmatis_MC2_155 ----VPVFVLVVLGLTLVGFAVTSLLD------LAPAWAALAGAVVLGIR
MLBr_01036|M.leprae_Br4923 RDRWLLIKCGVVLLLVFVAFIAHPVLH------TGPSLVGMLGAGILIVI
MAB_3634c|M.abscessus_ATCC_199 ATILLPVTLMLAKALSDVVIDNPKSLVQRIFDTIGTPLVALLAATLVAMV
. * : : ... ..: .* :: :
Rv3578|M.tuberculosis_H37Rv SLRRGH----TSVLRIARAVNVSFLVFVLALG-------VVVHAVMLNGM
Mb3609|M.bovis_AF2122/97 SLRRGH----TSVLRIARAVNVSFLVFVLALG-------VVVHAVMLNGM
MMAR_5078|M.marinum_M SLRHRH----TSVIEIARSANVSFLVFVLALG-------VVVQAVMLSGI
MUL_4154|M.ulcerans_Agy99 SLRHRH----TSVIEIARSANVSFLVFVLALG-------VVVQAVMLSGI
MAV_0577|M.avium_104 SLARGH----TTVTEIARSVHVSFLVFVLALG-------VVVQAVMRNGM
Mflv_1448|M.gilvum_PYR-GCK ALADRR----TTMSRIVVSLDIPFLIFVLCLG-------VVVDAVMRNGL
Mvan_5336|M.vanbaalenii_PYR-1 ALATRH----TTVTRIAAAADVPFLIFVLCLG-------VVVAAVMRNGL
TH_3461|M.thermoresistible__bu GLARGR----TTAEGVLSAANLPFLAFVVCLG-------IVVEAVRTAGL
MSMEG_6072|M.smegmatis_MC2_155 SFAQRR----STVRGIVRAVNVPFLAFVLCLG-------VVVDAVVLNGP
MLBr_01036|M.leprae_Br4923 SKLERS----DYLSSVKWETLLFFAGLFIMVG-------ALVKTDVVNQL
MAB_3634c|M.abscessus_ATCC_199 TLGKASGLDRIGVAGIIEKSLGPIAGIVFIVGAGGGFKQTLIDVGVGDAV
: : :.. :* :: .
Rv3578|M.tuberculosis_H37Rv AARMSAVLPTGSGLPALLGIAALAAVLANVVNNLPATLVLVPLVAAGGP-
Mb3609|M.bovis_AF2122/97 AARMSAVLPTGSGLPALLGIAALASVLANVVNNLPATLVLVPLVAAGGP-
MMAR_5078|M.marinum_M ADKMSAVVPSGSGLTALLVIATVAALLANVVNNLPATLVLMPLVAGNGP-
MUL_4154|M.ulcerans_Agy99 ADKMSAVVPSGSGLTALLVIATVAALLANVVNNLPTTLVLMPLVAGNGP-
MAV_0577|M.avium_104 DRAMSALLPSGSGLPALLAIAATAAVLANVVNNLPATLVLLPLVAPAGP-
Mflv_1448|M.gilvum_PYR-GCK ESAMQQVIPDGHGLLALLGIAAVAALLSNVVNNLPAVLVLLPLVAGSGP-
Mvan_5336|M.vanbaalenii_PYR-1 ESAMRDAIPEGQGLAALLGIAAVAAVLSNVVNNLPAVLVLLPLVTPIGP-
TH_3461|M.thermoresistible__bu DGALAAVLPDPGSLWGLLGIAAAAAVLANAVNNLPAVLALLPLVSAAGP-
MSMEG_6072|M.smegmatis_MC2_155 EAVMRDVLPDGDSLPALLGYAAIAAVLANLVNNLPAVLMLLPLVAAAGP-
MLBr_01036|M.leprae_Br4923 ARATTTLTG-GHELLTVVLTLGVSTLVSSIIDNIPYVATMTPIVSELVAS
MAB_3634c|M.abscessus_ATCC_199 SSWSEKWQIPALVLGWLIAVLIRLATGSATVATITAAGIVSPLAADMST-
* :: : : : .:. . : *:.: .
Rv3578|M.tuberculosis_H37Rv --------AAVLAVLLGVNIGPNLTYAGSLSNLLWRGVLRRHNVDASVGE
Mb3609|M.bovis_AF2122/97 --------AAVLAVLLGVNIGPNLTYAGSLSNLLWRGVLRRHNVDASVGE
MMAR_5078|M.marinum_M --------AAVLAVLIGVNIGPNLTYVGSLSNLLWRRVLRQHNVEAGVSE
MUL_4154|M.ulcerans_Agy99 --------AAVLAVLIGVNIGPNLTYVGSLSNLLWRRVLRQHNVEAGVSE
MAV_0577|M.avium_104 --------VAVLAVLIGVNIGPNLTYVGSLSNLLWRRVLRQHGVDAGVGE
Mflv_1448|M.gilvum_PYR-GCK --------AAVLAVLIGVNIGPNLTYVGSLANLLWRSVVRRD-VKAGFGE
Mvan_5336|M.vanbaalenii_PYR-1 --------AAVLAVLIGVNIGPNLTYVGSLANLLWRSVVRRD-MRVGFAE
TH_3461|M.thermoresistible__bu --------AAVLAVLIGVNIGPNLSYLGSLSNLLWRNAVQPD-IPAGFGE
MSMEG_6072|M.smegmatis_MC2_155 --------GAVLAVLIGVNVGPNLTYVGSLSNLLWRHVVHRQGLAAKAGE
MLBr_01036|M.leprae_Br4923 MPDQSHTDILWWALALGADFGGNLTAVGASANVVMLEIAKSAGTPISFWE
MAB_3634c|M.abscessus_ATCC_199 ----------AHVALLVLAVGAGSLFFSHVNDAGFWLVKEYFGMSVG-QT
. : .* . . : .
Rv3578|M.tuberculosis_H37Rv YTRLGLCTVPAALAMAVLALWASAQVLGI
Mb3609|M.bovis_AF2122/97 YTRLGLCTVPAALAMAVLALWASAQVLGI
MMAR_5078|M.marinum_M YTRLGLCTVPVALVAAVIGLWVSVRLLGL
MUL_4154|M.ulcerans_Agy99 YTRLGLCTVPVSLVAAVIGLWVSVRLLGL
MAV_0577|M.avium_104 YTRLGVCTVPVSLLVAVLALWASARLLGG
Mflv_1448|M.gilvum_PYR-GCK FSRIGVVTTPLVLVAAVLGLWTYVRLIGL
Mvan_5336|M.vanbaalenii_PYR-1 FSRAGLVTAPLTLVAAVLGLWAWIQLFGL
TH_3461|M.thermoresistible__bu FSRIGLMTAPLTLVASVLALWVSLQLFGT
MSMEG_6072|M.smegmatis_MC2_155 FSRVGVVTTPLTLVAAVLGLWAGLELFG-
MLBr_01036|M.leprae_Br4923 FTRKGIAVTVISIALAGIYLWLRYLVMS-
MAB_3634c|M.abscessus_ATCC_199 LKSWSVMETLISVVGFAMVLLLSVVV---
. .: . : : * :