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ALTLSVAALAAVLACALLRPRLQAIVAGLAAALVIVAGATTWRAAVGEISELAPVVAFLAAVLVLARLCD DEGLFRAAGTLMARATSGGQSRLLTTVFAISAAVTAILSLDATVILLTPVVLATARALAVPARPHAYATA HLANSASLLLPVSNLTNLLAFSAAGLSFLHFAAAMTLPWIAAIVVEFLLLRWLFAKDLATEPQRAVSVEP LDVPKFTLAVVVLTLAGFAVTSLLGFSPAWAALAGALVLGVRALADRRTTMSRIVVSLDIPFLIFVLCLG VVVDAVMRNGLESAMQQVIPDGHGLLALLGIAAVAALLSNVVNNLPAVLVLLPLVAGSGPAAVLAVLIGV NIGPNLTYVGSLANLLWRSVVRRDVKAGFGEFSRIGVVTTPLVLVAAVLGLWTYVRLIGL*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. gilvum PYR-GCK | Mflv_1448 | - | - | 100% (411) | arsenical pump membrane protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3609 | arsB2 | 1e-124 | 58.21% (414) | arsenical PUMP integral membrane protein ArsB2 |
M. tuberculosis H37Rv | Rv3578 | arsB2 | 1e-124 | 58.45% (414) | arsenical PUMP integral membrane protein ArsB2 |
M. leprae Br4923 | MLBr_01036 | - | 9e-26 | 24.80% (367) | putative membrane transport protein |
M. abscessus ATCC 19977 | - | - | - | - | - |
M. marinum M | MMAR_5078 | arsB2 | 1e-129 | 60.14% (414) | arsenical pump integral membrane protein ArsB2 |
M. avium 104 | MAV_0577 | - | 1e-123 | 58.60% (413) | arsenical pump membrane protein |
M. smegmatis MC2 155 | MSMEG_6072 | - | 1e-142 | 64.89% (413) | citrate transporter |
M. thermoresistible (build 8) | TH_3461 | - | 1e-139 | 64.65% (413) | PUTATIVE putative Arsenical pump membrane protein |
M. ulcerans Agy99 | MUL_4154 | arsB2 | 1e-126 | 59.18% (414) | arsenical pump integral membrane protein ArsB2 |
M. vanbaalenii PYR-1 | Mvan_5336 | - | 1e-173 | 78.10% (411) | arsenical pump membrane protein |
CLUSTAL 2.0.9 multiple sequence alignment Mb3609|M.bovis_AF2122/97 --------------MTLAVALILLAVVLGFAVARPRGWPEAAAAVPAAVI Rv3578|M.tuberculosis_H37Rv --------------MTLAVALILLAVVLGFAVARPRGWPEAAAAVPAAVI MMAR_5078|M.marinum_M --------------MTLTVALLLLAVVLAFAVARPRGWPEAVAAVPAAGI MUL_4154|M.ulcerans_Agy99 --------------MTLTVALLLLAVVLAFAVARPRGWPEAVAAVPAAGI MAV_0577|M.avium_104 --------------MALTVALVLLAVVLGFAVARPRGWPEAVAAVPAALL Mflv_1448|M.gilvum_PYR-GCK --------------MALTLSVAALAAVLACALLRPR--LQAIVAGLAAAL Mvan_5336|M.vanbaalenii_PYR-1 --------------MELILSVAALASVLAFALLRPHRWPEAVIAVPAAAL MSMEG_6072|M.smegmatis_MC2_155 MAAQRPLDRDRERALALTLALIALIVVLTFAMVRPNGWPEAVAAVPAAVL TH_3461|M.thermoresistible__bu --------------MAVTVASAALIAVLVSALTRPRGWPEAVVAVPAAAL MLBr_01036|M.leprae_Br4923 -----------------MSVIAITVFIVTYALIASDRVNKTLAALTGAAI :: *: . :: * .* : Mb3609|M.bovis_AF2122/97 LLAIGAISPQQAMAQVSG--LARVVAFLGAVLVLAKLCDDEGLFEAAGAA Rv3578|M.tuberculosis_H37Rv LLAIGAISPQQAMAQVSG--LARVVAFLGAVLVLAKLCDDEGLFEAAGAA MMAR_5078|M.marinum_M LIAMGAISPQQAAAQVSG--LAGVVAFLGAVLVLAKLCDDEGLFEAAGAA MUL_4154|M.ulcerans_Agy99 LIAMGAISPQQAAAQVSG--LAGMVAFLGAVLVLAKLCDDEGLSEAAGAA MAV_0577|M.avium_104 LVGVGAIPVAAAEQQIAD--LSGVVAFLGAVLVLAKLCDDEGLFEAAGAA Mflv_1448|M.gilvum_PYR-GCK VIVAGATTWRAAVGEISE--LAPVVAFLAAVLVLARLCDDEGLFRAAGTL Mvan_5336|M.vanbaalenii_PYR-1 VIASGAISWDDALAEVGR--LAPVVGFLAAVLVLARLCDDVGLFHTAGVM MSMEG_6072|M.smegmatis_MC2_155 LIALGAISVHDAVDEAGR--LLPVVGFLAAVLVLAHLCDDEGLFHAAGTL TH_3461|M.thermoresistible__bu VVLTGAIALPDALAVADR--LLPVVGFLAAVLVLARLCDDEGLFRAAGAA MLBr_01036|M.leprae_Br4923 VVTLPIINSEDVFYSHETGIDWEVIFLLLSMMIIVSVLRQTGVFEYVAIW :: . :: :* :::::. : : *: . .. Mb3609|M.bovis_AF2122/97 MARASAE-SHRLLRQVFAVSAAITAALCLDATVVLLTPVVLATVRRLRTP Rv3578|M.tuberculosis_H37Rv MARASAE-SHRLLRQVFAVSAAITAALCLDATVVLLTPVVLATVRRLRTP MMAR_5078|M.marinum_M MARSSRS-SHGLLGQVFVVAALITAALSLDATVVLLTPVVLATVRRLRTP MUL_4154|M.ulcerans_Agy99 MARSSPS-SHGLLGQVFVVAALITAALSLDATVVLLTPVVLATVRRLRTP MAV_0577|M.avium_104 IARGRVG-SAGMLRRVFVIASAITAVLSLDAAVVLLTPVVLAAVRRQRTA Mflv_1448|M.gilvum_PYR-GCK MARATSGGQSRLLTTVFAISAAVTAILSLDATVILLTPVVLATARALAVP Mvan_5336|M.vanbaalenii_PYR-1 MARATSGGQIRLLASVFAIAAGVTAILSLDATVVLLTPVVLATARTLAVP MSMEG_6072|M.smegmatis_MC2_155 MARASRGHPRKLLLRVFVIGATTTAVLSLDATVVLLTPVVLATARTLAIA TH_3461|M.thermoresistible__bu MARVSSGNPVRLLAMVFVVAAATTAILSLDATAVLLTPVVLATARRLGVA MLBr_01036|M.leprae_Br4923 TAKRSHGSPLRILLLLVLVMALGSALLDNVTTVLLIAPVTLLVCERLTIN *: :* :. : : :* * ::.:*::**.* . . Mb3609|M.bovis_AF2122/97 VRPYAYATAHLANAASLLLPVSNLTNLLAYHGAGISFTKFTLLMALPWLS Rv3578|M.tuberculosis_H37Rv VRPYAYATAHLANAASLLLPVSNLTNLLAYHGAGISFTKFTLLMALPWLS MMAR_5078|M.marinum_M VRPYAYATAHLANAASLLLPVSNLTNLLAYRGADISFTKFTLVMTLPWLL MUL_4154|M.ulcerans_Agy99 VRPYAYATAHLANAASPLLPVSNLTNLLAYRGADISFTKFTLVMTLPWLL MAV_0577|M.avium_104 VRPYAYATAHLANGASLLLPVSNLTNLLAFHTAQLSFTRFTLLMAAPWLA Mflv_1448|M.gilvum_PYR-GCK ARPHAYATAHLANSASLLLPVSNLTNLLAFSAAGLSFLHFAAAMTLPWIA Mvan_5336|M.vanbaalenii_PYR-1 PRPHAYATAHLANSASLLLPVSNLTNLLAFGAAGLSFLHFAAAMSLPWLA MSMEG_6072|M.smegmatis_MC2_155 PRPHAYASAHLANSASLLFPVSNLTNLLAFTVAGLSFVEFSAYMAIPWLA TH_3461|M.thermoresistible__bu PRPHAYATAHLANSASLLLPVSNLTNLLAFGVCGLSFTRFTALMTLPWLA MLBr_01036|M.leprae_Br4923 AAPFLMAEVFASNIGGAATLVGDPPNIIIASRAGFSFNDFLIHLTPIVII *. * .. :* .. *.: .*:: . :** * :: : Mb3609|M.bovis_AF2122/97 AVAAVYVVFRWFFARDLRVVPDRQQLKPAPR---------LPMFVLVVVA Rv3578|M.tuberculosis_H37Rv AVAAVYVVFRWFFARDLRVVPDRQQLKPAPR---------LPMFVLVVVA MMAR_5078|M.marinum_M AIAAVYVIFRWFFARDLVAEPNREHVGPPPR---------PPVFVLVVVA MUL_4154|M.ulcerans_Agy99 AIAAVYVILCWFFARDLVAEPNREHVGPPPR---------PPVFVLVVVA MAV_0577|M.avium_104 AVATLYAVFRGFFAKDLRVQPDPAALGAPPR---------PPVFVLVVVA Mflv_1448|M.gilvum_PYR-GCK AIVVEFLLLRWLFAKDLATEPQR-AVSVEPLD--------VPKFTLAVVV Mvan_5336|M.vanbaalenii_PYR-1 AIAVEFVLLRWFFAKDLAVEPRR-AAVTEPVE--------VPVFALVVLG MSMEG_6072|M.smegmatis_MC2_155 AVAVEFALLSWLFSAELRPRPVPETAPPPPE---------VPVFVLVVLG TH_3461|M.thermoresistible__bu AIACEFVLLRRLFRADLSPAPSTGDRPAEPVG--------VPVFVLTVLG MLBr_01036|M.leprae_Br4923 VTVVLSALLPRLFRGAFAVDPERVADIMSLNEREAIRDRWLLIKCGVVLL . . :: :* : * .*: Mb3609|M.bovis_AF2122/97 LTLGGFAVAESVGLAPTWAALAGAAVLALRSLRRGHTSVLRIARAVNVSF Rv3578|M.tuberculosis_H37Rv LTLGGFAVAESVGLAPTWAALAGAAVLALRSLRRGHTSVLRIARAVNVSF MMAR_5078|M.marinum_M LTLVGFATAESLGVAPAWAALAGASVLAVRSLRHRHTSVIEIARSANVSF MUL_4154|M.ulcerans_Agy99 LTLVGFATAESLGVAPAWAALAGASVLAVRSLRHRHTSVIEIARSANVSF MAV_0577|M.avium_104 LTLAGFAVAQSVGIAPAWVALCGASVLAVRSLARGHTTVTEIARSVHVSF Mflv_1448|M.gilvum_PYR-GCK LTLAGFAVTSLLGFSPAWAALAGALVLGVRALADRRTTMSRIVVSLDIPF Mvan_5336|M.vanbaalenii_PYR-1 LTLLGFAVTSLLGLSPAWAALAGALVLGVRALATRHTTVTRIAAAADVPF MSMEG_6072|M.smegmatis_MC2_155 LTLVGFAVTSLLDLAPAWAALAGAVVLGIRSFAQRRSTVRGIVRAVNVPF TH_3461|M.thermoresistible__bu LTLTGFAVTSWLGIAPAWAALAGALVLGVHGLARGRTTAEGVLSAANLPF MLBr_01036|M.leprae_Br4923 LVFVAFIAHPVLHTGPSLVGMLGAGILIVISKLERSDYLSSVKWETLLFF *.: .* . : .*: ..: ** :* : . : : * Mb3609|M.bovis_AF2122/97 LVFVLALGVVVHAVMLNGMAARMSAVLPTGSGLPALLGIAALASVLANVV Rv3578|M.tuberculosis_H37Rv LVFVLALGVVVHAVMLNGMAARMSAVLPTGSGLPALLGIAALAAVLANVV MMAR_5078|M.marinum_M LVFVLALGVVVQAVMLSGIADKMSAVVPSGSGLTALLVIATVAALLANVV MUL_4154|M.ulcerans_Agy99 LVFVLALGVVVQAVMLSGIADKMSAVVPSGSGLTALLVIATVAALLANVV MAV_0577|M.avium_104 LVFVLALGVVVQAVMRNGMDRAMSALLPSGSGLPALLAIAATAAVLANVV Mflv_1448|M.gilvum_PYR-GCK LIFVLCLGVVVDAVMRNGLESAMQQVIPDGHGLLALLGIAAVAALLSNVV Mvan_5336|M.vanbaalenii_PYR-1 LIFVLCLGVVVAAVMRNGLESAMRDAIPEGQGLAALLGIAAVAAVLSNVV MSMEG_6072|M.smegmatis_MC2_155 LAFVLCLGVVVDAVVLNGPEAVMRDVLPDGDSLPALLGYAAIAAVLANLV TH_3461|M.thermoresistible__bu LAFVVCLGIVVEAVRTAGLDGALAAVLPDPGSLWGLLGIAAAAAVLANAV MLBr_01036|M.leprae_Br4923 AGLFIMVGALVKTDVVNQLARATTTLTG-GHELLTVVLTLGVSTLVSSII :.: :* :* : * :: :::::. : Mb3609|M.bovis_AF2122/97 NNLPATLVLVPLVAAGGP---------AAVLAVLLGVNIGPNLTYAGSLS Rv3578|M.tuberculosis_H37Rv NNLPATLVLVPLVAAGGP---------AAVLAVLLGVNIGPNLTYAGSLS MMAR_5078|M.marinum_M NNLPATLVLMPLVAGNGP---------AAVLAVLIGVNIGPNLTYVGSLS MUL_4154|M.ulcerans_Agy99 NNLPTTLVLMPLVAGNGP---------AAVLAVLIGVNIGPNLTYVGSLS MAV_0577|M.avium_104 NNLPATLVLLPLVAPAGP---------VAVLAVLIGVNIGPNLTYVGSLS Mflv_1448|M.gilvum_PYR-GCK NNLPAVLVLLPLVAGSGP---------AAVLAVLIGVNIGPNLTYVGSLA Mvan_5336|M.vanbaalenii_PYR-1 NNLPAVLVLLPLVTPIGP---------AAVLAVLIGVNIGPNLTYVGSLA MSMEG_6072|M.smegmatis_MC2_155 NNLPAVLMLLPLVAAAGP---------GAVLAVLIGVNVGPNLTYVGSLS TH_3461|M.thermoresistible__bu NNLPAVLALLPLVSAAGP---------AAVLAVLIGVNIGPNLSYLGSLS MLBr_01036|M.leprae_Br4923 DNIPYVATMTPIVSELVASMPDQSHTDILWWALALGADFGGNLTAVGASA :*:* . : *:*: . *: :*.:.* **: *: : Mb3609|M.bovis_AF2122/97 NLLWRGVLRRHNVDASVGEYTRLGLCTVPAALAMAVLALWASAQVLGI Rv3578|M.tuberculosis_H37Rv NLLWRGVLRRHNVDASVGEYTRLGLCTVPAALAMAVLALWASAQVLGI MMAR_5078|M.marinum_M NLLWRRVLRQHNVEAGVSEYTRLGLCTVPVALVAAVIGLWVSVRLLGL MUL_4154|M.ulcerans_Agy99 NLLWRRVLRQHNVEAGVSEYTRLGLCTVPVSLVAAVIGLWVSVRLLGL MAV_0577|M.avium_104 NLLWRRVLRQHGVDAGVGEYTRLGVCTVPVSLLVAVLALWASARLLGG Mflv_1448|M.gilvum_PYR-GCK NLLWRSVVRRD-VKAGFGEFSRIGVVTTPLVLVAAVLGLWTYVRLIGL Mvan_5336|M.vanbaalenii_PYR-1 NLLWRSVVRRD-MRVGFAEFSRAGLVTAPLTLVAAVLGLWAWIQLFGL MSMEG_6072|M.smegmatis_MC2_155 NLLWRHVVHRQGLAAKAGEFSRVGVVTTPLTLVAAVLGLWAGLELFG- TH_3461|M.thermoresistible__bu NLLWRNAVQPD-IPAGFGEFSRIGLMTAPLTLVASVLALWVSLQLFGT MLBr_01036|M.leprae_Br4923 NVVMLEIAKSAGTPISFWEFTRKGIAVTVISIALAGIYLWLRYLVMS- *:: : *::* *: .. : : : ** ::.