For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MSIIAITVFVAGYALIASDRVSKTRVALTCAAIMVGAGIVGSDDVFYSHEAGIDWDVIFLLLGMMIIVSV LRHTGVFEYVAIWAVKRANAAPLRIMILLVLVTALGSALLDNVTTVLLIAPVTLLVCDRLGVNSTPFLVA EVFASNVGGAATLVGDPPNIIIASRAGLTFNDFLIHMAPAVLVVMIALIGLLPWLLGSVTAEPDRVADVL SLNEREAIHDRGLLIKCGVVLVLVFAAFIAHPVLHIQPSLVALLGAGVLVRFSGLERSDYLSSVEWDTLL FFAGLFVMVGALVKTGVVEQLARAATELTGGNELLTVGLILGISAPVSGIIDNIPYVATMTPIVTELVAA MPGHVHPDTFWWALALSADFGGNLTAVAASANVVMLGIARRSGTPISFWKFTRKGAVVTAVSLVLSAVYL WLRYFVFG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2685 | arsB1 | - | 100% (428) | PROBABLE ARSENIC-TRANSPORT INTEGRAL MEMBRANE PROTEIN ARSB1 |
| M. tuberculosis H37Rv | Rv2684 | arsA | 0.0 | 76.76% (426) | arsenic-transport integral membrane protein ArsA |
| M. tuberculosis H37Rv | Rv3578 | arsB2 | 3e-21 | 23.90% (431) | arsenical PUMP integral membrane protein ArsB2 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2704 | arsB1 | 0.0 | 99.53% (428) | arsenic-transport integral membrane protein ArsB1 |
| M. gilvum PYR-GCK | Mflv_1448 | - | 7e-25 | 24.24% (425) | arsenical pump membrane protein |
| M. leprae Br4923 | MLBr_01036 | - | 1e-179 | 74.24% (427) | putative membrane transport protein |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_2029 | arsB1 | 0.0 | 79.86% (427) | arsenic-transport integral membrane protein ArsB1 |
| M. avium 104 | MAV_3579 | - | 1e-172 | 71.33% (429) | citrate transporter |
| M. smegmatis MC2 155 | MSMEG_0851 | - | 1e-122 | 51.18% (424) | citrate transporter |
| M. thermoresistible (build 8) | TH_3461 | - | 4e-19 | 25.00% (440) | PUTATIVE putative Arsenical pump membrane protein |
| M. ulcerans Agy99 | MUL_3321 | arsA | 1e-169 | 69.09% (427) | arsenic-transport integral membrane protein ArsA |
| M. vanbaalenii PYR-1 | Mvan_5336 | - | 5e-27 | 24.83% (431) | arsenical pump membrane protein |
CLUSTAL 2.0.9 multiple sequence alignment
Rv2685|M.tuberculosis_H37Rv ---MSIIAITVFVAGYALIASDRVSKTRVALTCAAIMVGAGIVGSDDVFY
Mb2704|M.bovis_AF2122/97 ---MSIIAITVFVAGYALIASDRVSKTRVALTCAAIMVGAGIVGSDDVFY
MMAR_2029|M.marinum_M ---MSVIAIGVFVVTYALIASDRVSKTRAALVGAAIMLAVGIVDSHDVFY
MLBr_01036|M.leprae_Br4923 ---MSVIAITVFIVTYALIASDRVNKTLAALTGAAIVVTLPIINSEDVFY
MAV_3579|M.avium_104 ---MSVIAIAVFVVAYALIASDRVNKTFVALAGAAVVITLPLIRSDDVFY
MUL_3321|M.ulcerans_Agy99 ---MSIVAVAIFVVAYALIASERVNKTLVALAGAAIVVMLPVINSEDVFY
MSMEG_0851|M.smegmatis_MC2_155 -MLAPVLALTIFVVAFWFIATERADKVKTVLVAAGLMTLLGLVPGAEVFY
Mflv_1448|M.gilvum_PYR-GCK MALTLSVAALAAVLACALLRPR--LQAIVAGLAAALVIVAGATTWRAAVG
Mvan_5336|M.vanbaalenii_PYR-1 MELILSVAALASVLAFALLRPHRWPEAVIAVPAAALVIASGAISWDDALA
TH_3461|M.thermoresistible__bu MAVTVASAALIAVLVSALTRPRGWPEAVVAVPAAALVVLTGAIALPDALA
* : : . :. . *.:: ..
Rv2685|M.tuberculosis_H37Rv SHEAGIDWDVIFLLLGMMIIVSVLRHTGVFEYVAIWAVKRANAAPLRIMI
Mb2704|M.bovis_AF2122/97 SHEAGIDWDVIFLLLGMMIIVSVLRHTGVFEYVAIWAVKRANAAPLRIMI
MMAR_2029|M.marinum_M SHDTGIDWDVIFLLLGMMIIVSVLRQTGVFEYIAIWAVKRANGSPTRIMI
MLBr_01036|M.leprae_Br4923 SHETGIDWEVIFLLLSMMIIVSVLRQTGVFEYVAIWTAKRSHGSPLRILL
MAV_3579|M.avium_104 SRETGIDWDVIFLLLGMMIIVSVLRQTGVFEYVAIWSAKRARGSPLRVMI
MUL_3321|M.ulcerans_Agy99 SHETGVDWDVIFLLLGMMIIVSVLRQTGVFEYVAICAAKRARGKPLRIMI
MSMEG_0851|M.smegmatis_MC2_155 SEHEGIDWNVIFLLLGMMVIVGVVKQTGLFDFLAIWAAKRSRGKPFRLMV
Mflv_1448|M.gilvum_PYR-GCK EISE--LAPVVAFLAAVLVLARLCDDEGLFRAAGTLMARATSGGQSRLLT
Mvan_5336|M.vanbaalenii_PYR-1 EVGR--LAPVVGFLAAVLVLARLCDDVGLFHTAGVMMARATSGGQIRLLA
TH_3461|M.thermoresistible__bu VADR--LLPVVGFLAAVLVLARLCDDEGLFRAAGAAMARVSSGNPVRLLA
*: :* .::::. : . *:* . .: : . *::
Rv2685|M.tuberculosis_H37Rv LLVLVTALGSALLDNVTTVLLIAPVTLLVCDRLGVNSTPFLVAEVFASNV
Mb2704|M.bovis_AF2122/97 LLVLVTALGSALLDNVTTVLLIAPVTLLVCDRLGVNSTPFLVAEVFASNV
MMAR_2029|M.marinum_M LLVLVMAFGSALLDNVTTVLLIAPVTLLVCDRLAINPSPFLMAEVFAANI
MLBr_01036|M.leprae_Br4923 LLVLVMALGSALLDNVTTVLLIAPVTLLVCERLTINAAPFLMAEVFASNI
MAV_3579|M.avium_104 LLVLVTALASALLDNVTTVLLIAPVTLLVCDRLAIAAAPFLMAEVFASNV
MUL_3321|M.ulcerans_Agy99 LLVIVTAVASALLDNVTTVLLIAPVTLLVCDRLVINPAPYLMAEAFASNI
MSMEG_0851|M.smegmatis_MC2_155 MLMIITAFASPVLDNVTIILLVAPVTVVICDRLRIPPQPYLIAEVLASNI
Mflv_1448|M.gilvum_PYR-GCK TVFAISAAVTAILSLDATVILLTPVVLATARALAVPARPHAYATAHLANS
Mvan_5336|M.vanbaalenii_PYR-1 SVFAIAAGVTAILSLDATVVLLTPVVLATARTLAVPPRPHAYATAHLANS
TH_3461|M.thermoresistible__bu MVFVVAAATTAILSLDATAVLLTPVVLATARRLGVAPRPHAYATAHLANS
:. : * :.:*. : :*::**.: . * : . *. * . :*
Rv2685|M.tuberculosis_H37Rv GGAATLVGDPPNIIIASRAGLTFNDFLIHMAPAVLVVMIALIGLLPWLL-
Mb2704|M.bovis_AF2122/97 GGAATLVGDPPNIIIASRAGLTFNDFLIHMAPAVLVVMIALIGLLPWLL-
MMAR_2029|M.marinum_M GGAATLVGDPPNIIIASRAGLSFNDFLLNMAPVVLIVLVIFVALLPRLF-
MLBr_01036|M.leprae_Br4923 GGAATLVGDPPNIIIASRAGFSFNDFLIHLTPIVIIVTVVLSALLPRLFR
MAV_3579|M.avium_104 GGAATLVGDPPNIIIASRGGLSFNDFLVHLAPIVVIVVGVLIALLPRLFP
MUL_3321|M.ulcerans_Agy99 GGTATLVGDPPNIVIASKGGLTFNDFLIHLAPIVVIVMAVFILMLPRLFP
MSMEG_0851|M.smegmatis_MC2_155 GGAATLIGDPPNIIIGSRAGLTFNDFLIHMAPIVIVIFALFVVFTRVLFR
Mflv_1448|M.gilvum_PYR-GCK ASLLLPVSNLTNLLAFSAAGLSFLHFAAAMTLPWIAAIVVEFLLLRWLFA
Mvan_5336|M.vanbaalenii_PYR-1 ASLLLPVSNLTNLLAFGAAGLSFLHFAAAMSLPWLAAIAVEFVLLRWFFA
TH_3461|M.thermoresistible__bu ASLLLPVSNLTNLLAFGVCGLSFTRFTALMTLPWLAAIACEFVLLRRLFR
.. :.: .*:: . *::* * :: : : ::
Rv2685|M.tuberculosis_H37Rv GSVTAEPDRVADVLSLNEREAIHDRGLLIKCGVVLVLVFAAFIAHPVLHI
Mb2704|M.bovis_AF2122/97 GSVTAEPDRVADVLSLNEREAIHDRGLLIKCGVVLVLVFAAFIAHPVLHI
MMAR_2029|M.marinum_M GSVTVEPERVSDVMSLNEREAISDRKLLIKCGVVLLAVFATFIAHPVLHI
MLBr_01036|M.leprae_Br4923 GAFAVDPERVADIMSLNEREAIRDRWLLIKCGVVLLLVFVAFIAHPVLHT
MAV_3579|M.avium_104 GAFTVDPERVADVMSLEEKEAIRDPRLLVTCGVVLLAVFAAFIAHGPLHL
MUL_3321|M.ulcerans_Agy99 GSFEADPERVADVMSLEEKEAIRDHGLLIKCGIVLLLVFTAFVANSALHV
MSMEG_0851|M.smegmatis_MC2_155 KELRANHVHIEEVMALQERRAIKDMRLLVRSLIVLNIVIVGFALHSVFHV
Mflv_1448|M.gilvum_PYR-GCK KDLATEPQR-AVSVEP--------LDVPKFTLAVVVLTLAGFAVTSLLGF
Mvan_5336|M.vanbaalenii_PYR-1 KDLAVEPRR-AAVTEP--------VEVPVFALVVLGLTLLGFAVTSLLGL
TH_3461|M.thermoresistible__bu ADLSPAPSTGDRPAEP--------VGVPVFVLTVLGLTLTGFAVTSWLGI
. : *: .: * :
Rv2685|M.tuberculosis_H37Rv QPSLVALLGAGVLVRFSGLERSDYLSSVEWDTLLFFAGLFVMVGALVKTG
Mb2704|M.bovis_AF2122/97 QPSLVALLGAGVLVRFSGLERSDYLSSVEWDTLLFFAGLFVMVGALVKTG
MMAR_2029|M.marinum_M QPSVVALLGAGVLIIISGLGGRDYLASVEWETLLFFAGLFIMVGALVKTG
MLBr_01036|M.leprae_Br4923 GPSLVGMLGAGILIVISKLERSDYLSSVKWETLLFFAGLFIMVGALVKTD
MAV_3579|M.avium_104 EPSLVALLGAGILVVASRLQPADYLSGVEWDTLLFFAGLFVMVGALVKTG
MUL_3321|M.ulcerans_Agy99 KPSMVALIGAGILVVVSRLDHSDYLSSVEWDTLLFFVGLFIMVGALVKTG
MSMEG_0851|M.smegmatis_MC2_155 APSIVALLGAGVMLLVTDVDINEVLPEVEWPTLVFFMGLFVMVAGLTHTG
Mflv_1448|M.gilvum_PYR-GCK SPAWAALAGALVLGVRALADRRTTMSRIVVSLDIPFLIFVLCLGVVVDAV
Mvan_5336|M.vanbaalenii_PYR-1 SPAWAALAGALVLGVRALATRHTTVTRIAAAADVPFLIFVLCLGVVVAAV
TH_3461|M.thermoresistible__bu APAWAALAGALVLGVHGLARGRTTAEGVLSAANLPFLAFVVCLGIVVEAV
*: ..: ** :: : : * :.: :. :. :
Rv2685|M.tuberculosis_H37Rv VVEQLARAATELTG-GNELLTVGLILGISAPVSGIIDNIPYVATMTPIVT
Mb2704|M.bovis_AF2122/97 VVEQLARAATELTG-GNELLTVGLILGISAPVSGIIDNIPYVATMTPIVT
MMAR_2029|M.marinum_M VVDKLARASIELTG-GNELFTVLLIIGVSAPVSGIIDNIPYVATMTPIVT
MLBr_01036|M.leprae_Br4923 VVNQLARATTTLTG-GHELLTVVLTLGVSTLVSSIIDNIPYVATMTPIVS
MAV_3579|M.avium_104 VVKHLARLAITATG-GNTLTATMVILVASVVISGIVDNVPYAATMAPVVA
MUL_3321|M.ulcerans_Agy99 VVTQVAQMAVTATG-GNTLLATMVILASSLVISGIVNNVPYAATMTPIVA
MSMEG_0851|M.smegmatis_MC2_155 VIGELGSVAQSAFG-DNWLGAATALLFGSSIAGAFIDNIPYTATMTPVVE
Mflv_1448|M.gilvum_PYR-GCK MRNGLESAMQQVIPDGHGLLALLGIAAVAALLSNVVNNLPAVLVLLPLVA
Mvan_5336|M.vanbaalenii_PYR-1 MRNGLESAMRDAIPEGQGLAALLGIAAVAAVLSNVVNNLPAVLVLLPLVT
TH_3461|M.thermoresistible__bu RTAGLDGALAAVLPDPGSLWGLLGIAAAAAVLANAVNNLPAVLALLPLVS
: * : . ::*:* . .: *:*
Rv2685|M.tuberculosis_H37Rv ELVAAMPGHVHPDTFWWALALSADFGGNLTAVAASANVVMLGIARRSGTP
Mb2704|M.bovis_AF2122/97 ELVAAMPGHVHPDTFWWALALSADFGGNLTAVGASANVVMLGIARRSCTP
MMAR_2029|M.marinum_M ELVAVMPGQVNPDALWWALALGADFGGNLTAVGASANVVMLGIARRAGTP
MLBr_01036|M.leprae_Br4923 ELVASMPDQSHTDILWWALALGADFGGNLTAVGASANVVMLEIAKSAGTP
MAV_3579|M.avium_104 DLVPALGDHANPAVLWWSLALGTDFGGNLTAIGASANIVLLGIARRADNP
MUL_3321|M.ulcerans_Agy99 ELVPVLVDKGNPDVLWWALALGTDFGGDLTAIGASANVIVLGIAKRADNP
MSMEG_0851|M.smegmatis_MC2_155 SMVADAPDMVTGNALWWAFALGACFSGNGTAIAASANVVAIGIAKRAGHP
Mflv_1448|M.gilvum_PYR-GCK GSGPAAV---------LAVLIGVNIGPNLTYVGSLANLLWRSVVRR-DVK
Mvan_5336|M.vanbaalenii_PYR-1 PIGPAAV---------LAVLIGVNIGPNLTYVGSLANLLWRSVVRR-DMR
TH_3461|M.thermoresistible__bu AAGPAAV---------LAVLIGVNIGPNLSYLGSLSNLLWRNAVQP-DIP
. :. :.. :. : : :.: :*:: .:
Rv2685|M.tuberculosis_H37Rv ISFWKFTRKGAVVTAVSLVLSAVYLWLRYFVFG-
Mb2704|M.bovis_AF2122/97 ISFWKFTRKGAVVTAVSLVLSAVYLWLRYFVFG-
MMAR_2029|M.marinum_M ISFWEFTRKGIVVTTISLLVAAAYLWLRYFVWS-
MLBr_01036|M.leprae_Br4923 ISFWEFTRKGIAVTVISIALAGIYLWLRYLVMS-
MAV_3579|M.avium_104 ISFWEFTRKGVVVTAVSVALSALYLWLRYFVWG-
MUL_3321|M.ulcerans_Agy99 ISFWEFTRKGIVVTTMSLVLAAIYLWVRYFVLS-
MSMEG_0851|M.smegmatis_MC2_155 ISFWQFTRYGIVVTFLSTALAWVYVWLRYF----
Mflv_1448|M.gilvum_PYR-GCK AGFGEFSRIGVVTTPLVLVAAVLGLWTYVRLIGL
Mvan_5336|M.vanbaalenii_PYR-1 VGFAEFSRAGLVTAPLTLVAAVLGLWAWIQLFGL
TH_3461|M.thermoresistible__bu AGFGEFSRIGLMTAPLTLVASVLALWVSLQLFGT
.* :*:* * .: : : :*