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M. vanbaalenii PYR-1 Mvan_5336 (-)

annotation: arsenical pump membrane protein
coordinates: 5712982 - 5714223
length: 413

MELILSVAALASVLAFALLRPHRWPEAVIAVPAAALVIASGAISWDDALAEVGRLAPVVGFLAAVLVLAR
LCDDVGLFHTAGVMMARATSGGQIRLLASVFAIAAGVTAILSLDATVVLLTPVVLATARTLAVPPRPHAY
ATAHLANSASLLLPVSNLTNLLAFGAAGLSFLHFAAAMSLPWLAAIAVEFVLLRWFFAKDLAVEPRRAAV
TEPVEVPVFALVVLGLTLLGFAVTSLLGLSPAWAALAGALVLGVRALATRHTTVTRIAAAADVPFLIFVL
CLGVVVAAVMRNGLESAMRDAIPEGQGLAALLGIAAVAAVLSNVVNNLPAVLVLLPLVTPIGPAAVLAVL
IGVNIGPNLTYVGSLANLLWRSVVRRDMRVGFAEFSRAGLVTAPLTLVAAVLGLWAWIQLFGL
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. vanbaalenii PYR-1Mvan_5336--100% (413)arsenical pump membrane protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3609arsB21e-13260.63% (414) arsenical PUMP integral membrane protein ArsB2
M. gilvum PYR-GCKMflv_1448-1e-17378.10% (411) arsenical pump membrane protein
M. tuberculosis H37RvRv3578arsB21e-13360.87% (414) arsenical PUMP integral membrane protein ArsB2
M. leprae Br4923MLBr_01036-1e-2422.38% (420) putative membrane transport protein
M. abscessus ATCC 19977-----
M. marinum MMMAR_5078arsB21e-13662.56% (414) arsenical pump integral membrane protein ArsB2
M. avium 104MAV_0577-1e-12960.53% (413) arsenical pump membrane protein
M. smegmatis MC2 155MSMEG_6072-1e-15369.01% (413) citrate transporter
M. thermoresistible (build 8)TH_3461-1e-15068.52% (413) PUTATIVE putative Arsenical pump membrane protein
M. ulcerans Agy99MUL_4154arsB21e-13361.59% (414) arsenical pump integral membrane protein ArsB2

CLUSTAL 2.0.9 multiple sequence alignment


Mb3609|M.bovis_AF2122/97            --------------MTLAVALILLAVVLGFAVARPRGWPEAAAAVPAAVI
Rv3578|M.tuberculosis_H37Rv         --------------MTLAVALILLAVVLGFAVARPRGWPEAAAAVPAAVI
MMAR_5078|M.marinum_M               --------------MTLTVALLLLAVVLAFAVARPRGWPEAVAAVPAAGI
MUL_4154|M.ulcerans_Agy99           --------------MTLTVALLLLAVVLAFAVARPRGWPEAVAAVPAAGI
MAV_0577|M.avium_104                --------------MALTVALVLLAVVLGFAVARPRGWPEAVAAVPAALL
Mvan_5336|M.vanbaalenii_PYR-1       --------------MELILSVAALASVLAFALLRPHRWPEAVIAVPAAAL
Mflv_1448|M.gilvum_PYR-GCK          --------------MALTLSVAALAAVLACALLRPR--LQAIVAGLAAAL
MSMEG_6072|M.smegmatis_MC2_155      MAAQRPLDRDRERALALTLALIALIVVLTFAMVRPNGWPEAVAAVPAAVL
TH_3461|M.thermoresistible__bu      --------------MAVTVASAALIAVLVSALTRPRGWPEAVVAVPAAAL
MLBr_01036|M.leprae_Br4923          -----------------MSVIAITVFIVTYALIASDRVNKTLAALTGAAI
                                                              ::  *:  .    ::  *  .* :

Mb3609|M.bovis_AF2122/97            LLAIGAISPQQAMAQVSG--LARVVAFLGAVLVLAKLCDDEGLFEAAGAA
Rv3578|M.tuberculosis_H37Rv         LLAIGAISPQQAMAQVSG--LARVVAFLGAVLVLAKLCDDEGLFEAAGAA
MMAR_5078|M.marinum_M               LIAMGAISPQQAAAQVSG--LAGVVAFLGAVLVLAKLCDDEGLFEAAGAA
MUL_4154|M.ulcerans_Agy99           LIAMGAISPQQAAAQVSG--LAGMVAFLGAVLVLAKLCDDEGLSEAAGAA
MAV_0577|M.avium_104                LVGVGAIPVAAAEQQIAD--LSGVVAFLGAVLVLAKLCDDEGLFEAAGAA
Mvan_5336|M.vanbaalenii_PYR-1       VIASGAISWDDALAEVGR--LAPVVGFLAAVLVLARLCDDVGLFHTAGVM
Mflv_1448|M.gilvum_PYR-GCK          VIVAGATTWRAAVGEISE--LAPVVAFLAAVLVLARLCDDEGLFRAAGTL
MSMEG_6072|M.smegmatis_MC2_155      LIALGAISVHDAVDEAGR--LLPVVGFLAAVLVLAHLCDDEGLFHAAGTL
TH_3461|M.thermoresistible__bu      VVLTGAIALPDALAVADR--LLPVVGFLAAVLVLARLCDDEGLFRAAGAA
MLBr_01036|M.leprae_Br4923          VVTLPIINSEDVFYSHETGIDWEVIFLLLSMMIIVSVLRQTGVFEYVAIW
                                    ::         .           :: :* :::::. :  : *: . ..  

Mb3609|M.bovis_AF2122/97            MARASAE-SHRLLRQVFAVSAAITAALCLDATVVLLTPVVLATVRRLRTP
Rv3578|M.tuberculosis_H37Rv         MARASAE-SHRLLRQVFAVSAAITAALCLDATVVLLTPVVLATVRRLRTP
MMAR_5078|M.marinum_M               MARSSRS-SHGLLGQVFVVAALITAALSLDATVVLLTPVVLATVRRLRTP
MUL_4154|M.ulcerans_Agy99           MARSSPS-SHGLLGQVFVVAALITAALSLDATVVLLTPVVLATVRRLRTP
MAV_0577|M.avium_104                IARGRVG-SAGMLRRVFVIASAITAVLSLDAAVVLLTPVVLAAVRRQRTA
Mvan_5336|M.vanbaalenii_PYR-1       MARATSGGQIRLLASVFAIAAGVTAILSLDATVVLLTPVVLATARTLAVP
Mflv_1448|M.gilvum_PYR-GCK          MARATSGGQSRLLTTVFAISAAVTAILSLDATVILLTPVVLATARALAVP
MSMEG_6072|M.smegmatis_MC2_155      MARASRGHPRKLLLRVFVIGATTTAVLSLDATVVLLTPVVLATARTLAIA
TH_3461|M.thermoresistible__bu      MARVSSGNPVRLLAMVFVVAAATTAILSLDATAVLLTPVVLATARRLGVA
MLBr_01036|M.leprae_Br4923          TAKRSHGSPLRILLLLVLVMALGSALLDNVTTVLLIAPVTLLVCERLTIN
                                     *:        :*  :. : :  :* *   ::.:*::**.* . .     

Mb3609|M.bovis_AF2122/97            VRPYAYATAHLANAASLLLPVSNLTNLLAYHGAGISFTKFTLLMALPWLS
Rv3578|M.tuberculosis_H37Rv         VRPYAYATAHLANAASLLLPVSNLTNLLAYHGAGISFTKFTLLMALPWLS
MMAR_5078|M.marinum_M               VRPYAYATAHLANAASLLLPVSNLTNLLAYRGADISFTKFTLVMTLPWLL
MUL_4154|M.ulcerans_Agy99           VRPYAYATAHLANAASPLLPVSNLTNLLAYRGADISFTKFTLVMTLPWLL
MAV_0577|M.avium_104                VRPYAYATAHLANGASLLLPVSNLTNLLAFHTAQLSFTRFTLLMAAPWLA
Mvan_5336|M.vanbaalenii_PYR-1       PRPHAYATAHLANSASLLLPVSNLTNLLAFGAAGLSFLHFAAAMSLPWLA
Mflv_1448|M.gilvum_PYR-GCK          ARPHAYATAHLANSASLLLPVSNLTNLLAFSAAGLSFLHFAAAMTLPWIA
MSMEG_6072|M.smegmatis_MC2_155      PRPHAYASAHLANSASLLFPVSNLTNLLAFTVAGLSFVEFSAYMAIPWLA
TH_3461|M.thermoresistible__bu      PRPHAYATAHLANSASLLLPVSNLTNLLAFGVCGLSFTRFTALMTLPWLA
MLBr_01036|M.leprae_Br4923          AAPFLMAEVFASNIGGAATLVGDPPNIIIASRAGFSFNDFLIHLTPIVII
                                      *.  * .. :* ..    *.: .*::    . :**  *   ::   : 

Mb3609|M.bovis_AF2122/97            AVAAVYVVFRWFFARDLRVVPDRQQLKPAPR---------LPMFVLVVVA
Rv3578|M.tuberculosis_H37Rv         AVAAVYVVFRWFFARDLRVVPDRQQLKPAPR---------LPMFVLVVVA
MMAR_5078|M.marinum_M               AIAAVYVIFRWFFARDLVAEPNREHVGPPPR---------PPVFVLVVVA
MUL_4154|M.ulcerans_Agy99           AIAAVYVILCWFFARDLVAEPNREHVGPPPR---------PPVFVLVVVA
MAV_0577|M.avium_104                AVATLYAVFRGFFAKDLRVQPDPAALGAPPR---------PPVFVLVVVA
Mvan_5336|M.vanbaalenii_PYR-1       AIAVEFVLLRWFFAKDLAVEPRR-AAVTEPVE--------VPVFALVVLG
Mflv_1448|M.gilvum_PYR-GCK          AIVVEFLLLRWLFAKDLATEPQR-AVSVEPLD--------VPKFTLAVVV
MSMEG_6072|M.smegmatis_MC2_155      AVAVEFALLSWLFSAELRPRPVPETAPPPPE---------VPVFVLVVLG
TH_3461|M.thermoresistible__bu      AIACEFVLLRRLFRADLSPAPSTGDRPAEPVG--------VPVFVLTVLG
MLBr_01036|M.leprae_Br4923          VTVVLSALLPRLFRGAFAVDPERVADIMSLNEREAIRDRWLLIKCGVVLL
                                    . .    ::  :*   :   *                         .*: 

Mb3609|M.bovis_AF2122/97            LTLGGFAVAESVGLAPTWAALAGAAVLALRSLRRGHTSVLRIARAVNVSF
Rv3578|M.tuberculosis_H37Rv         LTLGGFAVAESVGLAPTWAALAGAAVLALRSLRRGHTSVLRIARAVNVSF
MMAR_5078|M.marinum_M               LTLVGFATAESLGVAPAWAALAGASVLAVRSLRHRHTSVIEIARSANVSF
MUL_4154|M.ulcerans_Agy99           LTLVGFATAESLGVAPAWAALAGASVLAVRSLRHRHTSVIEIARSANVSF
MAV_0577|M.avium_104                LTLAGFAVAQSVGIAPAWVALCGASVLAVRSLARGHTTVTEIARSVHVSF
Mvan_5336|M.vanbaalenii_PYR-1       LTLLGFAVTSLLGLSPAWAALAGALVLGVRALATRHTTVTRIAAAADVPF
Mflv_1448|M.gilvum_PYR-GCK          LTLAGFAVTSLLGFSPAWAALAGALVLGVRALADRRTTMSRIVVSLDIPF
MSMEG_6072|M.smegmatis_MC2_155      LTLVGFAVTSLLDLAPAWAALAGAVVLGIRSFAQRRSTVRGIVRAVNVPF
TH_3461|M.thermoresistible__bu      LTLTGFAVTSWLGIAPAWAALAGALVLGVHGLARGRTTAEGVLSAANLPF
MLBr_01036|M.leprae_Br4923          LVFVAFIAHPVLHTGPSLVGMLGAGILIVISKLERSDYLSSVKWETLLFF
                                    *.: .* .   :  .*: ..: ** :* : .          :     : *

Mb3609|M.bovis_AF2122/97            LVFVLALGVVVHAVMLNGMAARMSAVLPTGSGLPALLGIAALASVLANVV
Rv3578|M.tuberculosis_H37Rv         LVFVLALGVVVHAVMLNGMAARMSAVLPTGSGLPALLGIAALAAVLANVV
MMAR_5078|M.marinum_M               LVFVLALGVVVQAVMLSGIADKMSAVVPSGSGLTALLVIATVAALLANVV
MUL_4154|M.ulcerans_Agy99           LVFVLALGVVVQAVMLSGIADKMSAVVPSGSGLTALLVIATVAALLANVV
MAV_0577|M.avium_104                LVFVLALGVVVQAVMRNGMDRAMSALLPSGSGLPALLAIAATAAVLANVV
Mvan_5336|M.vanbaalenii_PYR-1       LIFVLCLGVVVAAVMRNGLESAMRDAIPEGQGLAALLGIAAVAAVLSNVV
Mflv_1448|M.gilvum_PYR-GCK          LIFVLCLGVVVDAVMRNGLESAMQQVIPDGHGLLALLGIAAVAALLSNVV
MSMEG_6072|M.smegmatis_MC2_155      LAFVLCLGVVVDAVVLNGPEAVMRDVLPDGDSLPALLGYAAIAAVLANLV
TH_3461|M.thermoresistible__bu      LAFVVCLGIVVEAVRTAGLDGALAAVLPDPGSLWGLLGIAAAAAVLANAV
MLBr_01036|M.leprae_Br4923          AGLFIMVGALVKTDVVNQLARATTTLTG-GHELLTVVLTLGVSTLVSSII
                                      :.: :* :* :                   *  ::     :::::. :

Mb3609|M.bovis_AF2122/97            NNLPATLVLVPLVAAGGP---------AAVLAVLLGVNIGPNLTYAGSLS
Rv3578|M.tuberculosis_H37Rv         NNLPATLVLVPLVAAGGP---------AAVLAVLLGVNIGPNLTYAGSLS
MMAR_5078|M.marinum_M               NNLPATLVLMPLVAGNGP---------AAVLAVLIGVNIGPNLTYVGSLS
MUL_4154|M.ulcerans_Agy99           NNLPTTLVLMPLVAGNGP---------AAVLAVLIGVNIGPNLTYVGSLS
MAV_0577|M.avium_104                NNLPATLVLLPLVAPAGP---------VAVLAVLIGVNIGPNLTYVGSLS
Mvan_5336|M.vanbaalenii_PYR-1       NNLPAVLVLLPLVTPIGP---------AAVLAVLIGVNIGPNLTYVGSLA
Mflv_1448|M.gilvum_PYR-GCK          NNLPAVLVLLPLVAGSGP---------AAVLAVLIGVNIGPNLTYVGSLA
MSMEG_6072|M.smegmatis_MC2_155      NNLPAVLMLLPLVAAAGP---------GAVLAVLIGVNVGPNLTYVGSLS
TH_3461|M.thermoresistible__bu      NNLPAVLALLPLVSAAGP---------AAVLAVLIGVNIGPNLSYLGSLS
MLBr_01036|M.leprae_Br4923          DNIPYVATMTPIVSELVASMPDQSHTDILWWALALGADFGGNLTAVGASA
                                    :*:* .  : *:*:   .             *: :*.:.* **:  *: :

Mb3609|M.bovis_AF2122/97            NLLWRGVLRRHNVDASVGEYTRLGLCTVPAALAMAVLALWASAQVLGI
Rv3578|M.tuberculosis_H37Rv         NLLWRGVLRRHNVDASVGEYTRLGLCTVPAALAMAVLALWASAQVLGI
MMAR_5078|M.marinum_M               NLLWRRVLRQHNVEAGVSEYTRLGLCTVPVALVAAVIGLWVSVRLLGL
MUL_4154|M.ulcerans_Agy99           NLLWRRVLRQHNVEAGVSEYTRLGLCTVPVSLVAAVIGLWVSVRLLGL
MAV_0577|M.avium_104                NLLWRRVLRQHGVDAGVGEYTRLGVCTVPVSLLVAVLALWASARLLGG
Mvan_5336|M.vanbaalenii_PYR-1       NLLWRSVVRRD-MRVGFAEFSRAGLVTAPLTLVAAVLGLWAWIQLFGL
Mflv_1448|M.gilvum_PYR-GCK          NLLWRSVVRRD-VKAGFGEFSRIGVVTTPLVLVAAVLGLWTYVRLIGL
MSMEG_6072|M.smegmatis_MC2_155      NLLWRHVVHRQGLAAKAGEFSRVGVVTTPLTLVAAVLGLWAGLELFG-
TH_3461|M.thermoresistible__bu      NLLWRNAVQPD-IPAGFGEFSRIGLMTAPLTLVASVLALWVSLQLFGT
MLBr_01036|M.leprae_Br4923          NVVMLEIAKSAGTPISFWEFTRKGIAVTVISIALAGIYLWLRYLVMS-
                                    *::     :         *::* *: ..   :  : : **    ::.