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NAGLVLLAEQANVAHTTSEVRLLAAVLLSIGAIILLITRLRLHPFLALLLGSGTLAAAASVPFDKLLGSF VTGFGSTIAGVGLLIGLGAMLGRLLADSGGANIVADAVLTRSSPRLLPWAVASIAAVLGLPLFFEVGVVL LIPIVLLVARRGNVPLLRVGIPALAGLSVLHGLVPPHPGPLVAVDALKADLGVTLAFGLVAAVPTLIVAG PLYARIAERWVGPLDIPTATAPEAERTGPAPSVVAVLATILLPVTLMLAKALSDVVIDNPKSLVQRIFDT IGTPLVALLAATLVAMVTLGKASGLDRIGVAGIIEKSLGPIAGIVFIVGAGGGFKQTLIDVGVGDAVSSW SEKWQIPALVLGWLIAVLIRLATGSATVATITAAGIVSPLAADMSTAHVALLVLAVGAGSLFFSHVNDAG FWLVKEYFGMSVGQTLKSWSVMETLISVVGFAMVLLLSVVV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3634c | - | - | 100% (462) | putative gluconate permease |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3609 | arsB2 | 6e-05 | 26.58% (237) | arsenical PUMP integral membrane protein ArsB2 |
| M. gilvum PYR-GCK | Mflv_0503 | - | 2e-76 | 36.29% (474) | gluconate transporter |
| M. tuberculosis H37Rv | Rv3578 | arsB2 | 7e-05 | 26.58% (237) | arsenical PUMP integral membrane protein ArsB2 |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_5078 | arsB2 | 4e-09 | 25.82% (395) | arsenical pump integral membrane protein ArsB2 |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_3789 | - | 5e-87 | 38.96% (462) | inner membrane permease YgbN |
| M. thermoresistible (build 8) | TH_1008 | - | 3e-05 | 23.91% (368) | AMINOGLYCOSIDES/TETRACYCLINE-TRANSPORT INTEGRAL MEMBRANE |
| M. ulcerans Agy99 | MUL_4154 | arsB2 | 1e-08 | 24.56% (395) | arsenical pump integral membrane protein ArsB2 |
| M. vanbaalenii PYR-1 | Mvan_5912 | - | 6e-78 | 37.34% (474) | gluconate transporter |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3609|M.bovis_AF2122/97 --------------------MTLAVALILLAVVLGFAVARPRG-------
Rv3578|M.tuberculosis_H37Rv --------------------MTLAVALILLAVVLGFAVARPRG-------
MMAR_5078|M.marinum_M --------------------MTLTVALLLLAVVLAFAVARPRG-------
MUL_4154|M.ulcerans_Agy99 --------------------MTLTVALLLLAVVLAFAVARPRG-------
Mflv_0503|M.gilvum_PYR-GCK -----------MEAIDP--AYGTTTLLLIAAG--AVALLLFLI-------
Mvan_5912|M.vanbaalenii_PYR-1 -----------MEAIDP--AYGTGTLLLIAAG--AVALLLFLI-------
MSMEG_3789|M.smegmatis_MC2_155 -----------MTTFVDWLRHDTAGLLTLAAV--SIAVLLLLI-------
MAB_3634c|M.abscessus_ATCC_199 -----MNAGLVLLAEQANVAHTTSEVRLLAAVLLSIGAIILLI-------
TH_1008|M.thermoresistible__bu MRRATAAAIRPPRGHNRTIAISAGSLAVLLGALDTYVVITIMVDIMRDVG
: .
Mb3609|M.bovis_AF2122/97 -WPEAAAAVPAAVILLAIGAISPQQAMAQVSG-----------------L
Rv3578|M.tuberculosis_H37Rv -WPEAAAAVPAAVILLAIGAISPQQAMAQVSG-----------------L
MMAR_5078|M.marinum_M -WPEAVAAVPAAGILIAMGAISPQQAAAQVSG-----------------L
MUL_4154|M.ulcerans_Agy99 -WPEAVAAVPAAGILIAMGAISPQQAAAQVSG-----------------L
Mflv_0503|M.gilvum_PYR-GCK -IKVKLHAFVALVLVSLLTALAAGIPVADVP--------SALTFGFSNTL
Mvan_5912|M.vanbaalenii_PYR-1 -IKVKLHAFIALVLVSLLTALAAGIPVADVP--------SALSFGFSNTL
MSMEG_3789|M.smegmatis_MC2_155 -IKMKVEPFIALIVVSVAVALTAGIPVAELVGTPAKSGDSLLETGFGGIL
MAB_3634c|M.abscessus_ATCC_199 -TRLRLHPFLALLLGSGTLAAAASVPFDKLLG--------SFVTGFGSTI
TH_1008|M.thermoresistible__bu IALNKIHQVTPIITGYLLGYIAAMPLLGRASDRFGRKMLIQVGLAGFAIG
. . :.
Mb3609|M.bovis_AF2122/97 ARVVAFLGAVLVLAKLCDDEGLFEAAGAAMARASAESHRLLRQVFAVSAA
Rv3578|M.tuberculosis_H37Rv ARVVAFLGAVLVLAKLCDDEGLFEAAGAAMARASAESHRLLRQVFAVSAA
MMAR_5078|M.marinum_M AGVVAFLGAVLVLAKLCDDEGLFEAAGAAMARSSRSSHGLLGQVFVVAAL
MUL_4154|M.ulcerans_Agy99 AGMVAFLGAVLVLAKLCDDEGLSEAAGAAMARSSPSSHGLLGQVFVVAAL
Mflv_0503|M.gilvum_PYR-GCK GSVALLVGFGVMIGRLLEITGGAQVLADTLIGRF-GEKRAPLALGVAALL
Mvan_5912|M.vanbaalenii_PYR-1 GSVALLVGFGVMIGRLLEITGGAQVLADTLIGRF-GEKRAPFALGVAALL
MSMEG_3789|M.smegmatis_MC2_155 GHITVIIGLGTVLGAMLERSGGADVLTTRLLNLF-GPKGAPLAMGITGVI
MAB_3634c|M.abscessus_ATCC_199 AGVGLLIGLGAMLGRLLADSGGANIVADAVLTRS-SPRLLPWAVASIAAV
TH_1008|M.thermoresistible__bu SVVTALAGDLQSLHMLVTGRIIQGAASGALLPVTLALAADLWAERNRAGV
. : : * : : : .
Mb3609|M.bovis_AF2122/97 IT---AALCLDATVVLLTPVVLATVRRLRTPVRPYAY-ATAHLANAASLL
Rv3578|M.tuberculosis_H37Rv IT---AALCLDATVVLLTPVVLATVRRLRTPVRPYAY-ATAHLANAASLL
MMAR_5078|M.marinum_M IT---AALSLDATVVLLTPVVLATVRRLRTPVRPYAY-ATAHLANAASLL
MUL_4154|M.ulcerans_Agy99 IT---AALSLDATVVLLTPVVLATVRRLRTPVRPYAY-ATAHLANAASPL
Mflv_0503|M.gilvum_PYR-GCK FG---FPIFFDAGLVVFLPIIMTVARRFGGSLLLYAFPAAGAFAAMHALV
Mvan_5912|M.vanbaalenii_PYR-1 FG---FPIFFDAGLVVFLPIIMTVARRFGGSLLLYAFPAAGAFAAMHALV
MSMEG_3789|M.smegmatis_MC2_155 LG---IPVFFDIGIFILAPLVYVAAKRGGRSLVLYALPMLAGLSMTHAFL
MAB_3634c|M.abscessus_ATCC_199 LG---LPLFFEVGVVLLIPIVLLVARRGNVPLLRVGIPALAGLSVLHGLV
TH_1008|M.thermoresistible__bu LGGIGAAQELGAVLGPLYGIAMVWLFGAWESVFWVNVPLAALAMVMIHFS
: . : : : : .: .
Mb3609|M.bovis_AF2122/97 LPVS---NLTNLLAYHG-AGISFTKFT-LLMALPWLSAVAAVYVVFRWFF
Rv3578|M.tuberculosis_H37Rv LPVS---NLTNLLAYHG-AGISFTKFT-LLMALPWLSAVAAVYVVFRWFF
MMAR_5078|M.marinum_M LPVS---NLTNLLAYRG-ADISFTKFT-LVMTLPWLLAIAAVYVIFRWFF
MUL_4154|M.ulcerans_Agy99 LPVS---NLTNLLAYRG-ADISFTKFT-LVMTLPWLLAIAAVYVILCWFF
Mflv_0503|M.gilvum_PYR-GCK PPHP---GPVAAAELLG-ANIGLTLLVGAPVAVAAWYVGAYLVSQAMGRR
Mvan_5912|M.vanbaalenii_PYR-1 PPHP---GPVAAAELLG-ANIGLTLLIGAPVAVASWYVGAFLVSQFIGRR
MSMEG_3789|M.smegmatis_MC2_155 PPHP---GPVAAAGLLG-VSLGWIIIMGLACGIPAWFVSGVVWGAWIGKR
MAB_3634c|M.abscessus_ATCC_199 PPHP---GPLVAVDALK-ADLGVTLAFGLVAAVPTLIVAGPLYARIAERW
TH_1008|M.thermoresistible__bu LPARDPDGPRERIDVVGGVLLGITLFLIVVGLYNPQPSAREVVPTWRLWL
* . . :. :
Mb3609|M.bovis_AF2122/97 AR---------------------------------DLRVVPDRQQLKPAP
Rv3578|M.tuberculosis_H37Rv AR---------------------------------DLRVVPDRQQLKPAP
MMAR_5078|M.marinum_M AR---------------------------------DLVAEPNREHVGPPP
MUL_4154|M.ulcerans_Agy99 AR---------------------------------DLVAEPNREHVGPPP
Mflv_0503|M.gilvum_PYR-GCK IH-VDVPTALFGEINGGRDTEHPTDDTPGTGAATTATRTAPAFATVLGVL
Mvan_5912|M.vanbaalenii_PYR-1 VH-VDIPTSLFGEINGGRDTD--TGETSGAATTTTATRTAPAFITVLGVL
MSMEG_3789|M.smegmatis_MC2_155 VH-VEVPEEFVPEED------------------EADTASPPSLLLVGFII
MAB_3634c|M.abscessus_ATCC_199 VGPLDIPTATAPEAER--------------------TGPAPSVVAVLATI
TH_1008|M.thermoresistible__bu LAAAAVTLIGFFVWERRARTKLIDPAGVRFRPFLAALGASFVAGAALMVT
Mb3609|M.bovis_AF2122/97 RLPMFVLVVVALTLGGFAVAESVG-----------LAPTWAALAGAAVLA
Rv3578|M.tuberculosis_H37Rv RLPMFVLVVVALTLGGFAVAESVG-----------LAPTWAALAGAAVLA
MMAR_5078|M.marinum_M RPPVFVLVVVALTLVGFATAESLG-----------VAPAWAALAGASVLA
MUL_4154|M.ulcerans_Agy99 RPPVFVLVVVALTLVGFATAESLG-----------VAPAWAALAGASVLA
Mflv_0503|M.gilvum_PYR-GCK LLPFVLISFNTVIDTLMTAGVIEEGATWAE-YLKLIGTTSIALLITVIVA
Mvan_5912|M.vanbaalenii_PYR-1 LLPFVLISFNTVVDTLMTAGVIEEGATWAE-YLKLIGTTSIALLITVIVA
MSMEG_3789|M.smegmatis_MC2_155 VAPMLLILAATLADVLLDGGRLLS-------VLTLIGNPAIALTIAVMLA
MAB_3634c|M.abscessus_ATCC_199 LLPVTLMLAKALSDVVIDNPKSLVQR-----IFDTIGTPLVALLAATLVA
TH_1008|M.thermoresistible__bu LVNVELFGQGVLGKDQFEAAMLLLRFLIALPIGALIGGWLATRVGDRIVT
. :: .: : :. : :::
Mb3609|M.bovis_AF2122/97 LRSLRRG--------------HTSVLRIARAVN--VSFLVFVLALGVVVH
Rv3578|M.tuberculosis_H37Rv LRSLRRG--------------HTSVLRIARAVN--VSFLVFVLALGVVVH
MMAR_5078|M.marinum_M VRSLRHR--------------HTSVIEIARSAN--VSFLVFVLALGVVVQ
MUL_4154|M.ulcerans_Agy99 VRSLRHR--------------HTSVIEIARSAN--VSFLVFVLALGVVVQ
Mflv_0503|M.gilvum_PYR-GCK TLVLGLR-G----------RSMGTVSDILDKALGPICAIILITGAGGMFG
Mvan_5912|M.vanbaalenii_PYR-1 TLALGLR-G----------RSMATVTDILDQALGPICAIILITGAGGMFG
MSMEG_3789|M.smegmatis_MC2_155 LYLLGIRRG----------ITAPELAKISGVSLRPVGMILLVVGAGAFFG
MAB_3634c|M.abscessus_ATCC_199 MVTLGKASG----------LDRIGVAGIIEKSLGPIAGIVFIVGAGGGFK
TH_1008|M.thermoresistible__bu FVGLLIAAGGFWLISHWPVDLLAARHDLGVVTLPVLDTDLAIVGIGLGLV
* : : : : . * .
Mb3609|M.bovis_AF2122/97 AVMLNGMAARMSAVLPTGSGLPALLGIAALASVLANVVN-----------
Rv3578|M.tuberculosis_H37Rv AVMLNGMAARMSAVLPTGSGLPALLGIAALAAVLANVVN-----------
MMAR_5078|M.marinum_M AVMLSGIADKMSAVVPSGSGLTALLVIATVAALLANVVN-----------
MUL_4154|M.ulcerans_Agy99 AVMLSGIADKMSAVVPSGSGLTALLVIATVAALLANVVN-----------
Mflv_0503|M.gilvum_PYR-GCK GVLRLSGIGDALSGSLSNLGISLILQAFIISTLLRVAQG-----------
Mvan_5912|M.vanbaalenii_PYR-1 GVLRLSGIGDALSGSLSNLGISLILQAFVISTLLRVAQG-----------
MSMEG_3789|M.smegmatis_MC2_155 AVLRATGIGDALADSMTAIGLPVIVSAYLISCALRIAQG-----------
MAB_3634c|M.abscessus_ATCC_199 QTLIDVGVGDAVSSWSEKWQIPALVLGWLIAVLIRLATG-----------
TH_1008|M.thermoresistible__bu IGPLTSAALRVVPAAEHGIASAAVVVARMIGMVIGLAALSAWGLYRFNQH
. . :: :. : .
Mb3609|M.bovis_AF2122/97 --------------NLPATLVLVP-----LVAAGGPAAVLAVLLGVNIGP
Rv3578|M.tuberculosis_H37Rv --------------NLPATLVLVP-----LVAAGGPAAVLAVLLGVNIGP
MMAR_5078|M.marinum_M --------------NLPATLVLMP-----LVAGNGPAAVLAVLIGVNIGP
MUL_4154|M.ulcerans_Agy99 --------------NLPTTLVLMP-----LVAGNGPAAVLAVLIGVNIGP
Mflv_0503|M.gilvum_PYR-GCK --------------SATVALTTTAGLISAAVAAADLSNLQLVALVMAIAA
Mvan_5912|M.vanbaalenii_PYR-1 --------------SATVALTTTAGLLSAAVAAAQLSNLQLTALVMAIAA
MSMEG_3789|M.smegmatis_MC2_155 --------------SATVAIVTTAGIIQASVADGHHSPAQIALIVVAVSA
MAB_3634c|M.abscessus_ATCC_199 --------------SATVATITAAGIVSP--LAADMSTAHVALLVLAVGA
TH_1008|M.thermoresistible__bu LQSLAAREPGGDSLAARLAAEAARYREAYAMQYGEIFAITALLCVAGALL
:
Mb3609|M.bovis_AF2122/97 NLTYAGS---LSNLLWRGVLRRHNVDASVGEYTRLGLCTVPAALAMAVLA
Rv3578|M.tuberculosis_H37Rv NLTYAGS---LSNLLWRGVLRRHNVDASVGEYTRLGLCTVPAALAMAVLA
MMAR_5078|M.marinum_M NLTYVGS---LSNLLWRRVLRQHNVEAGVSEYTRLGLCTVPVALVAAVIG
MUL_4154|M.ulcerans_Agy99 NLTYVGS---LSNLLWRRVLRQHNVEAGVSEYTRLGLCTVPVSLVAAVIG
Mflv_0503|M.gilvum_PYR-GCK GATVLSH---VNDSGFWLVNRFFNMDVKTTLKTWTVLETTLGLSVFVISL
Mvan_5912|M.vanbaalenii_PYR-1 GATVLSH---VNDSGFWLVSRFFGMDVKTTLKTWTVMETTLGLSAFAISL
MSMEG_3789|M.smegmatis_MC2_155 GSIIASH---VNDGGFWIVSRYFNMSVKDTLKTWTVLETTLSVVGFAMAG
MAB_3634c|M.abscessus_ATCC_199 GSLFFSH---VNDAGFWLVKEYFGMSVGQTLKSWSVMETLISVVGFAMVL
TH_1008|M.thermoresistible__bu GLLIAGHGDRADDTGTPDGSVWDLHGSGDDDTPTRVIGRQVPLPSMEQTV
. . .: . :
Mb3609|M.bovis_AF2122/97 LWASAQVLGI
Rv3578|M.tuberculosis_H37Rv LWASAQVLGI
MMAR_5078|M.marinum_M LWVSVRLLGL
MUL_4154|M.ulcerans_Agy99 LWVSVRLLGL
Mflv_0503|M.gilvum_PYR-GCK GLWAIA----
Mvan_5912|M.vanbaalenii_PYR-1 GLWAIA----
MSMEG_3789|M.smegmatis_MC2_155 LLWLVV----
MAB_3634c|M.abscessus_ATCC_199 LLSVVV----
TH_1008|M.thermoresistible__bu RMPRPPGD--