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ALTVALVLLAVVLGFAVARPRGWPEAVAAVPAALLLVGVGAIPVAAAEQQIADLSGVVAFLGAVLVLAKL CDDEGLFEAAGAAIARGRVGSAGMLRRVFVIASAITAVLSLDAAVVLLTPVVLAAVRRQRTAVRPYAYAT AHLANGASLLLPVSNLTNLLAFHTAQLSFTRFTLLMAAPWLAAVATLYAVFRGFFAKDLRVQPDPAALGA PPRPPVFVLVVVALTLAGFAVAQSVGIAPAWVALCGASVLAVRSLARGHTTVTEIARSVHVSFLVFVLAL GVVVQAVMRNGMDRAMSALLPSGSGLPALLAIAATAAVLANVVNNLPATLVLLPLVAPAGPVAVLAVLIG VNIGPNLTYVGSLSNLLWRRVLRQHGVDAGVGEYTRLGVCTVPVSLLVAVLALWASARLLGG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_0577 | - | - | 100% (413) | arsenical pump membrane protein |
| M. avium 104 | MAV_3579 | - | 2e-23 | 25.41% (370) | citrate transporter |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3609 | arsB2 | 1e-168 | 75.00% (412) | arsenical PUMP integral membrane protein ArsB2 |
| M. gilvum PYR-GCK | Mflv_1448 | - | 1e-123 | 58.60% (413) | arsenical pump membrane protein |
| M. tuberculosis H37Rv | Rv3578 | arsB2 | 1e-169 | 75.24% (412) | arsenical PUMP integral membrane protein ArsB2 |
| M. leprae Br4923 | MLBr_01036 | - | 2e-19 | 21.68% (429) | putative membrane transport protein |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_5078 | arsB2 | 1e-168 | 74.51% (412) | arsenical pump integral membrane protein ArsB2 |
| M. smegmatis MC2 155 | MSMEG_6072 | - | 1e-132 | 61.74% (413) | citrate transporter |
| M. thermoresistible (build 8) | TH_3461 | - | 1e-124 | 59.86% (416) | PUTATIVE putative Arsenical pump membrane protein |
| M. ulcerans Agy99 | MUL_4154 | arsB2 | 1e-164 | 73.30% (412) | arsenical pump integral membrane protein ArsB2 |
| M. vanbaalenii PYR-1 | Mvan_5336 | - | 1e-129 | 60.53% (413) | arsenical pump membrane protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3609|M.bovis_AF2122/97 --------------MTLAVALILLAVVLGFAVARPRGWPEAAAAVPAAVI
Rv3578|M.tuberculosis_H37Rv --------------MTLAVALILLAVVLGFAVARPRGWPEAAAAVPAAVI
MMAR_5078|M.marinum_M --------------MTLTVALLLLAVVLAFAVARPRGWPEAVAAVPAAGI
MUL_4154|M.ulcerans_Agy99 --------------MTLTVALLLLAVVLAFAVARPRGWPEAVAAVPAAGI
MAV_0577|M.avium_104 --------------MALTVALVLLAVVLGFAVARPRGWPEAVAAVPAALL
MSMEG_6072|M.smegmatis_MC2_155 MAAQRPLDRDRERALALTLALIALIVVLTFAMVRPNGWPEAVAAVPAAVL
TH_3461|M.thermoresistible__bu --------------MAVTVASAALIAVLVSALTRPRGWPEAVVAVPAAAL
Mflv_1448|M.gilvum_PYR-GCK --------------MALTLSVAALAAVLACALLRPR--LQAIVAGLAAAL
Mvan_5336|M.vanbaalenii_PYR-1 --------------MELILSVAALASVLAFALLRPHRWPEAVIAVPAAAL
MLBr_01036|M.leprae_Br4923 -----------------MSVIAITVFIVTYALIASDRVNKTLAALTGAAI
:: *: . :: * .* :
Mb3609|M.bovis_AF2122/97 LLAIGAISPQQAMAQVSG--LARVVAFLGAVLVLAKLCDDEGLFEAAGAA
Rv3578|M.tuberculosis_H37Rv LLAIGAISPQQAMAQVSG--LARVVAFLGAVLVLAKLCDDEGLFEAAGAA
MMAR_5078|M.marinum_M LIAMGAISPQQAAAQVSG--LAGVVAFLGAVLVLAKLCDDEGLFEAAGAA
MUL_4154|M.ulcerans_Agy99 LIAMGAISPQQAAAQVSG--LAGMVAFLGAVLVLAKLCDDEGLSEAAGAA
MAV_0577|M.avium_104 LVGVGAIPVAAAEQQIAD--LSGVVAFLGAVLVLAKLCDDEGLFEAAGAA
MSMEG_6072|M.smegmatis_MC2_155 LIALGAISVHDAVDEAGR--LLPVVGFLAAVLVLAHLCDDEGLFHAAGTL
TH_3461|M.thermoresistible__bu VVLTGAIALPDALAVADR--LLPVVGFLAAVLVLARLCDDEGLFRAAGAA
Mflv_1448|M.gilvum_PYR-GCK VIVAGATTWRAAVGEISE--LAPVVAFLAAVLVLARLCDDEGLFRAAGTL
Mvan_5336|M.vanbaalenii_PYR-1 VIASGAISWDDALAEVGR--LAPVVGFLAAVLVLARLCDDVGLFHTAGVM
MLBr_01036|M.leprae_Br4923 VVTLPIINSEDVFYSHETGIDWEVIFLLLSMMIIVSVLRQTGVFEYVAIW
:: . :: :* :::::. : : *: . ..
Mb3609|M.bovis_AF2122/97 MARASAE-SHRLLRQVFAVSAAITAALCLDATVVLLTPVVLATVRRLRTP
Rv3578|M.tuberculosis_H37Rv MARASAE-SHRLLRQVFAVSAAITAALCLDATVVLLTPVVLATVRRLRTP
MMAR_5078|M.marinum_M MARSSRS-SHGLLGQVFVVAALITAALSLDATVVLLTPVVLATVRRLRTP
MUL_4154|M.ulcerans_Agy99 MARSSPS-SHGLLGQVFVVAALITAALSLDATVVLLTPVVLATVRRLRTP
MAV_0577|M.avium_104 IARGRVG-SAGMLRRVFVIASAITAVLSLDAAVVLLTPVVLAAVRRQRTA
MSMEG_6072|M.smegmatis_MC2_155 MARASRGHPRKLLLRVFVIGATTTAVLSLDATVVLLTPVVLATARTLAIA
TH_3461|M.thermoresistible__bu MARVSSGNPVRLLAMVFVVAAATTAILSLDATAVLLTPVVLATARRLGVA
Mflv_1448|M.gilvum_PYR-GCK MARATSGGQSRLLTTVFAISAAVTAILSLDATVILLTPVVLATARALAVP
Mvan_5336|M.vanbaalenii_PYR-1 MARATSGGQIRLLASVFAIAAGVTAILSLDATVVLLTPVVLATARTLAVP
MLBr_01036|M.leprae_Br4923 TAKRSHGSPLRILLLLVLVMALGSALLDNVTTVLLIAPVTLLVCERLTIN
*: :* :. : : :* * ::.:*::**.* . .
Mb3609|M.bovis_AF2122/97 VRPYAYATAHLANAASLLLPVSNLTNLLAYHGAGISFTKFTLLMALPWLS
Rv3578|M.tuberculosis_H37Rv VRPYAYATAHLANAASLLLPVSNLTNLLAYHGAGISFTKFTLLMALPWLS
MMAR_5078|M.marinum_M VRPYAYATAHLANAASLLLPVSNLTNLLAYRGADISFTKFTLVMTLPWLL
MUL_4154|M.ulcerans_Agy99 VRPYAYATAHLANAASPLLPVSNLTNLLAYRGADISFTKFTLVMTLPWLL
MAV_0577|M.avium_104 VRPYAYATAHLANGASLLLPVSNLTNLLAFHTAQLSFTRFTLLMAAPWLA
MSMEG_6072|M.smegmatis_MC2_155 PRPHAYASAHLANSASLLFPVSNLTNLLAFTVAGLSFVEFSAYMAIPWLA
TH_3461|M.thermoresistible__bu PRPHAYATAHLANSASLLLPVSNLTNLLAFGVCGLSFTRFTALMTLPWLA
Mflv_1448|M.gilvum_PYR-GCK ARPHAYATAHLANSASLLLPVSNLTNLLAFSAAGLSFLHFAAAMTLPWIA
Mvan_5336|M.vanbaalenii_PYR-1 PRPHAYATAHLANSASLLLPVSNLTNLLAFGAAGLSFLHFAAAMSLPWLA
MLBr_01036|M.leprae_Br4923 AAPFLMAEVFASNIGGAATLVGDPPNIIIASRAGFSFNDFLIHLTPIVII
*. * .. :* .. *.: .*:: . :** * :: :
Mb3609|M.bovis_AF2122/97 AVAAVYVVFRWFFARDLRVVPDRQQLKPAPR---------LPMFVLVVVA
Rv3578|M.tuberculosis_H37Rv AVAAVYVVFRWFFARDLRVVPDRQQLKPAPR---------LPMFVLVVVA
MMAR_5078|M.marinum_M AIAAVYVIFRWFFARDLVAEPNREHVGPPPR---------PPVFVLVVVA
MUL_4154|M.ulcerans_Agy99 AIAAVYVILCWFFARDLVAEPNREHVGPPPR---------PPVFVLVVVA
MAV_0577|M.avium_104 AVATLYAVFRGFFAKDLRVQPDPAALGAPPR---------PPVFVLVVVA
MSMEG_6072|M.smegmatis_MC2_155 AVAVEFALLSWLFSAELRPRPVPETAPPPPE---------VPVFVLVVLG
TH_3461|M.thermoresistible__bu AIACEFVLLRRLFRADLSPAPSTGDRPAEPVG--------VPVFVLTVLG
Mflv_1448|M.gilvum_PYR-GCK AIVVEFLLLRWLFAKDLATEPQR-AVSVEPLD--------VPKFTLAVVV
Mvan_5336|M.vanbaalenii_PYR-1 AIAVEFVLLRWFFAKDLAVEPRR-AAVTEPVE--------VPVFALVVLG
MLBr_01036|M.leprae_Br4923 VTVVLSALLPRLFRGAFAVDPERVADIMSLNEREAIRDRWLLIKCGVVLL
. . :: :* : * .*:
Mb3609|M.bovis_AF2122/97 LTLGGFAVAESVGLAPTWAALAGAAVLALRSLRRGHTSVLRIARAVNVSF
Rv3578|M.tuberculosis_H37Rv LTLGGFAVAESVGLAPTWAALAGAAVLALRSLRRGHTSVLRIARAVNVSF
MMAR_5078|M.marinum_M LTLVGFATAESLGVAPAWAALAGASVLAVRSLRHRHTSVIEIARSANVSF
MUL_4154|M.ulcerans_Agy99 LTLVGFATAESLGVAPAWAALAGASVLAVRSLRHRHTSVIEIARSANVSF
MAV_0577|M.avium_104 LTLAGFAVAQSVGIAPAWVALCGASVLAVRSLARGHTTVTEIARSVHVSF
MSMEG_6072|M.smegmatis_MC2_155 LTLVGFAVTSLLDLAPAWAALAGAVVLGIRSFAQRRSTVRGIVRAVNVPF
TH_3461|M.thermoresistible__bu LTLTGFAVTSWLGIAPAWAALAGALVLGVHGLARGRTTAEGVLSAANLPF
Mflv_1448|M.gilvum_PYR-GCK LTLAGFAVTSLLGFSPAWAALAGALVLGVRALADRRTTMSRIVVSLDIPF
Mvan_5336|M.vanbaalenii_PYR-1 LTLLGFAVTSLLGLSPAWAALAGALVLGVRALATRHTTVTRIAAAADVPF
MLBr_01036|M.leprae_Br4923 LVFVAFIAHPVLHTGPSLVGMLGAGILIVISKLERSDYLSSVKWETLLFF
*.: .* . : .*: ..: ** :* : . : : *
Mb3609|M.bovis_AF2122/97 LVFVLALGVVVHAVMLNGMAARMSAVLPTGSGLPALLGIAALASVLANVV
Rv3578|M.tuberculosis_H37Rv LVFVLALGVVVHAVMLNGMAARMSAVLPTGSGLPALLGIAALAAVLANVV
MMAR_5078|M.marinum_M LVFVLALGVVVQAVMLSGIADKMSAVVPSGSGLTALLVIATVAALLANVV
MUL_4154|M.ulcerans_Agy99 LVFVLALGVVVQAVMLSGIADKMSAVVPSGSGLTALLVIATVAALLANVV
MAV_0577|M.avium_104 LVFVLALGVVVQAVMRNGMDRAMSALLPSGSGLPALLAIAATAAVLANVV
MSMEG_6072|M.smegmatis_MC2_155 LAFVLCLGVVVDAVVLNGPEAVMRDVLPDGDSLPALLGYAAIAAVLANLV
TH_3461|M.thermoresistible__bu LAFVVCLGIVVEAVRTAGLDGALAAVLPDPGSLWGLLGIAAAAAVLANAV
Mflv_1448|M.gilvum_PYR-GCK LIFVLCLGVVVDAVMRNGLESAMQQVIPDGHGLLALLGIAAVAALLSNVV
Mvan_5336|M.vanbaalenii_PYR-1 LIFVLCLGVVVAAVMRNGLESAMRDAIPEGQGLAALLGIAAVAAVLSNVV
MLBr_01036|M.leprae_Br4923 AGLFIMVGALVKTDVVNQLARATTTLTG-GHELLTVVLTLGVSTLVSSII
:.: :* :* : * :: :::::. :
Mb3609|M.bovis_AF2122/97 NNLPATLVLVPLVAAGGP---------AAVLAVLLGVNIGPNLTYAGSLS
Rv3578|M.tuberculosis_H37Rv NNLPATLVLVPLVAAGGP---------AAVLAVLLGVNIGPNLTYAGSLS
MMAR_5078|M.marinum_M NNLPATLVLMPLVAGNGP---------AAVLAVLIGVNIGPNLTYVGSLS
MUL_4154|M.ulcerans_Agy99 NNLPTTLVLMPLVAGNGP---------AAVLAVLIGVNIGPNLTYVGSLS
MAV_0577|M.avium_104 NNLPATLVLLPLVAPAGP---------VAVLAVLIGVNIGPNLTYVGSLS
MSMEG_6072|M.smegmatis_MC2_155 NNLPAVLMLLPLVAAAGP---------GAVLAVLIGVNVGPNLTYVGSLS
TH_3461|M.thermoresistible__bu NNLPAVLALLPLVSAAGP---------AAVLAVLIGVNIGPNLSYLGSLS
Mflv_1448|M.gilvum_PYR-GCK NNLPAVLVLLPLVAGSGP---------AAVLAVLIGVNIGPNLTYVGSLA
Mvan_5336|M.vanbaalenii_PYR-1 NNLPAVLVLLPLVTPIGP---------AAVLAVLIGVNIGPNLTYVGSLA
MLBr_01036|M.leprae_Br4923 DNIPYVATMTPIVSELVASMPDQSHTDILWWALALGADFGGNLTAVGASA
:*:* . : *:*: . *: :*.:.* **: *: :
Mb3609|M.bovis_AF2122/97 NLLWRGVLRRHNVDASVGEYTRLGLCTVPAALAMAVLALWASAQVLGI
Rv3578|M.tuberculosis_H37Rv NLLWRGVLRRHNVDASVGEYTRLGLCTVPAALAMAVLALWASAQVLGI
MMAR_5078|M.marinum_M NLLWRRVLRQHNVEAGVSEYTRLGLCTVPVALVAAVIGLWVSVRLLGL
MUL_4154|M.ulcerans_Agy99 NLLWRRVLRQHNVEAGVSEYTRLGLCTVPVSLVAAVIGLWVSVRLLGL
MAV_0577|M.avium_104 NLLWRRVLRQHGVDAGVGEYTRLGVCTVPVSLLVAVLALWASARLLGG
MSMEG_6072|M.smegmatis_MC2_155 NLLWRHVVHRQGLAAKAGEFSRVGVVTTPLTLVAAVLGLWAGLELFG-
TH_3461|M.thermoresistible__bu NLLWRNAVQPD-IPAGFGEFSRIGLMTAPLTLVASVLALWVSLQLFGT
Mflv_1448|M.gilvum_PYR-GCK NLLWRSVVRRD-VKAGFGEFSRIGVVTTPLVLVAAVLGLWTYVRLIGL
Mvan_5336|M.vanbaalenii_PYR-1 NLLWRSVVRRD-MRVGFAEFSRAGLVTAPLTLVAAVLGLWAWIQLFGL
MLBr_01036|M.leprae_Br4923 NVVMLEIAKSAGTPISFWEFTRKGIAVTVISIALAGIYLWLRYLVMS-
*:: : *::* *: .. : : : ** ::.