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VSVVAVTIFVAAYVLIASDRVNKTMVALTGAAAVVVLPVITSHDIFYSHDTGIDWDVIFLLVGMMIIVGV LRQTGVFEYTAIWAAKRARGSPLRIMILLVLVSALASALLDNVTTVLLIAPVTLLVCDRLNINTTSFLMA EVFASNIGGAATLVGDPPNIIVASRAGLTFNDFMLHLTPLVVIVLIALIAVLPRLFGSITVEADRIADVM ALDEGEAIRDRGLLVKCGAVLVLVFAAFVAHPVLHIQPSLVALLGAGMLIVVSGLTRSEYLSSVEWDTLL FFAGLFIMVGALVKTGVVNDLARAATQLTGGNIVATAFLILGVSAPISGIIDNIPYVATMTPLVAELVAV MGGQPSTDTPWWALALGADFGGNLTAIGASANVVMLGIARRAGAPISFWEFTRKGAVVTAVSIALAAIYL WLRYFVLLH
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2684 | arsA | - | 100% (429) | PROBABLE ARSENIC-TRANSPORT INTEGRAL MEMBRANE PROTEIN ARSA |
| M. tuberculosis H37Rv | Rv2685 | arsB1 | 0.0 | 76.76% (426) | arsenic-transport integral membrane protein ArsB1 |
| M. tuberculosis H37Rv | Rv3578 | arsB2 | 4e-21 | 25.46% (377) | arsenical PUMP integral membrane protein ArsB2 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2703 | arsA | 0.0 | 100.00% (429) | arsenic-transport integral membrane protein ArsA |
| M. gilvum PYR-GCK | Mflv_1448 | - | 5e-26 | 25.12% (426) | arsenical pump membrane protein |
| M. leprae Br4923 | MLBr_01036 | - | 0.0 | 74.07% (428) | putative membrane transport protein |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_2029 | arsB1 | 0.0 | 75.82% (426) | arsenic-transport integral membrane protein ArsB1 |
| M. avium 104 | MAV_3579 | - | 1e-176 | 72.83% (427) | citrate transporter |
| M. smegmatis MC2 155 | MSMEG_0851 | - | 1e-125 | 52.94% (425) | citrate transporter |
| M. thermoresistible (build 8) | TH_3461 | - | 9e-22 | 24.83% (435) | PUTATIVE putative Arsenical pump membrane protein |
| M. ulcerans Agy99 | MUL_3321 | arsA | 1e-175 | 71.73% (428) | arsenic-transport integral membrane protein ArsA |
| M. vanbaalenii PYR-1 | Mvan_5336 | - | 2e-25 | 24.88% (426) | arsenical pump membrane protein |
CLUSTAL 2.0.9 multiple sequence alignment
Rv2684|M.tuberculosis_H37Rv ---MSVVAVTIFVAAYVLIASDRVNKTMVALTGAAAVVVLPVITSHDIFY
Mb2703|M.bovis_AF2122/97 ---MSVVAVTIFVAAYVLIASDRVNKTMVALTGAAAVVVLPVITSHDIFY
MLBr_01036|M.leprae_Br4923 ---MSVIAITVFIVTYALIASDRVNKTLAALTGAAIVVTLPIINSEDVFY
MMAR_2029|M.marinum_M ---MSVIAIGVFVVTYALIASDRVSKTRAALVGAAIMLAVGIVDSHDVFY
MAV_3579|M.avium_104 ---MSVIAIAVFVVAYALIASDRVNKTFVALAGAAVVITLPLIRSDDVFY
MUL_3321|M.ulcerans_Agy99 ---MSIVAVAIFVVAYALIASERVNKTLVALAGAAIVVMLPVINSEDVFY
MSMEG_0851|M.smegmatis_MC2_155 -MLAPVLALTIFVVAFWFIATERADKVKTVLVAAGLMTLLGLVPGAEVFY
Mflv_1448|M.gilvum_PYR-GCK MALTLSVAALAAVLACALLRPR--LQAIVAGLAAALVIVAGATTWRAAVG
Mvan_5336|M.vanbaalenii_PYR-1 MELILSVAALASVLAFALLRPHRWPEAVIAVPAAALVIASGAISWDDALA
TH_3461|M.thermoresistible__bu MAVTVASAALIAVLVSALTRPRGWPEAVVAVPAAALVVLTGAIALPDALA
* : . : . :. . .*. : .
Rv2684|M.tuberculosis_H37Rv SHDTGIDWDVIFLLVGMMIIVGVLRQTGVFEYTAIWAAKRARGSPLRIMI
Mb2703|M.bovis_AF2122/97 SHDTGIDWDVIFLLVGMMIIVGVLRQTGVFEYTAIWAAKRARGSPLRIMI
MLBr_01036|M.leprae_Br4923 SHETGIDWEVIFLLLSMMIIVSVLRQTGVFEYVAIWTAKRSHGSPLRILL
MMAR_2029|M.marinum_M SHDTGIDWDVIFLLLGMMIIVSVLRQTGVFEYIAIWAVKRANGSPTRIMI
MAV_3579|M.avium_104 SRETGIDWDVIFLLLGMMIIVSVLRQTGVFEYVAIWSAKRARGSPLRVMI
MUL_3321|M.ulcerans_Agy99 SHETGVDWDVIFLLLGMMIIVSVLRQTGVFEYVAICAAKRARGKPLRIMI
MSMEG_0851|M.smegmatis_MC2_155 SEHEGIDWNVIFLLLGMMVIVGVVKQTGLFDFLAIWAAKRSRGKPFRLMV
Mflv_1448|M.gilvum_PYR-GCK EISE--LAPVVAFLAAVLVLARLCDDEGLFRAAGTLMARATSGGQSRLLT
Mvan_5336|M.vanbaalenii_PYR-1 EVGR--LAPVVGFLAAVLVLARLCDDVGLFHTAGVMMARATSGGQIRLLA
TH_3461|M.thermoresistible__bu VADR--LLPVVGFLAAVLVLARLCDDEGLFRAAGAAMARVSSGNPVRLLA
*: :* .::::. : : *:* . .: : * *::
Rv2684|M.tuberculosis_H37Rv LLVLVSALASALLDNVTTVLLIAPVTLLVCDRLNINTTSFLMAEVFASNI
Mb2703|M.bovis_AF2122/97 LLVLVSALASALLDNVTTVLLIAPVTLLVCDRLNINTTSFLMAEVFASNI
MLBr_01036|M.leprae_Br4923 LLVLVMALGSALLDNVTTVLLIAPVTLLVCERLTINAAPFLMAEVFASNI
MMAR_2029|M.marinum_M LLVLVMAFGSALLDNVTTVLLIAPVTLLVCDRLAINPSPFLMAEVFAANI
MAV_3579|M.avium_104 LLVLVTALASALLDNVTTVLLIAPVTLLVCDRLAIAAAPFLMAEVFASNV
MUL_3321|M.ulcerans_Agy99 LLVIVTAVASALLDNVTTVLLIAPVTLLVCDRLVINPAPYLMAEAFASNI
MSMEG_0851|M.smegmatis_MC2_155 MLMIITAFASPVLDNVTIILLVAPVTVVICDRLRIPPQPYLIAEVLASNI
Mflv_1448|M.gilvum_PYR-GCK TVFAISAAVTAILSLDATVILLTPVVLATARALAVPARPHAYATAHLANS
Mvan_5336|M.vanbaalenii_PYR-1 SVFAIAAGVTAILSLDATVVLLTPVVLATARTLAVPPRPHAYATAHLANS
TH_3461|M.thermoresistible__bu MVFVVAAATTAILSLDATAVLLTPVVLATARRLGVAPRPHAYATAHLANS
:. : * :.:*. : :*::**.: . * : . .. * . :*
Rv2684|M.tuberculosis_H37Rv GGAATLVGDPPNIIVASRAGLTFNDFMLHLTPLVVIVLIALIAVLPRLF-
Mb2703|M.bovis_AF2122/97 GGAATLVGDPPNIIVASRAGLTFNDFMLHLTPLVVIVLIALIAVLPRLF-
MLBr_01036|M.leprae_Br4923 GGAATLVGDPPNIIIASRAGFSFNDFLIHLTPIVIIVTVVLSALLPRLFR
MMAR_2029|M.marinum_M GGAATLVGDPPNIIIASRAGLSFNDFLLNMAPVVLIVLVIFVALLPRLF-
MAV_3579|M.avium_104 GGAATLVGDPPNIIIASRGGLSFNDFLVHLAPIVVIVVGVLIALLPRLFP
MUL_3321|M.ulcerans_Agy99 GGTATLVGDPPNIVIASKGGLTFNDFLIHLAPIVVIVMAVFILMLPRLFP
MSMEG_0851|M.smegmatis_MC2_155 GGAATLIGDPPNIIIGSRAGLTFNDFLIHMAPIVIVIFALFVVFTRVLFR
Mflv_1448|M.gilvum_PYR-GCK ASLLLPVSNLTNLLAFSAAGLSFLHFAAAMTLPWIAAIVVEFLLLRWLFA
Mvan_5336|M.vanbaalenii_PYR-1 ASLLLPVSNLTNLLAFGAAGLSFLHFAAAMSLPWLAAIAVEFVLLRWFFA
TH_3461|M.thermoresistible__bu ASLLLPVSNLTNLLAFGVCGLSFTRFTALMTLPWLAAIACEFVLLRRLFR
.. :.: .*:: . *::* * :: : . :*
Rv2684|M.tuberculosis_H37Rv GSITVEADRIADVMALDEGEAIRDRGLLVKCGAVLVLVFAAFVAHPVLHI
Mb2703|M.bovis_AF2122/97 GSITVEADRIADVMALDEGEAIRDRGLLVKCGAVLVLVFAAFVAHPVLHI
MLBr_01036|M.leprae_Br4923 GAFAVDPERVADIMSLNEREAIRDRWLLIKCGVVLLLVFVAFIAHPVLHT
MMAR_2029|M.marinum_M GSVTVEPERVSDVMSLNEREAISDRKLLIKCGVVLLAVFATFIAHPVLHI
MAV_3579|M.avium_104 GAFTVDPERVADVMSLEEKEAIRDPRLLVTCGVVLLAVFAAFIAHGPLHL
MUL_3321|M.ulcerans_Agy99 GSFEADPERVADVMSLEEKEAIRDHGLLIKCGIVLLLVFTAFVANSALHV
MSMEG_0851|M.smegmatis_MC2_155 KELRANHVHIEEVMALQERRAIKDMRLLVRSLIVLNIVIVGFALHSVFHV
Mflv_1448|M.gilvum_PYR-GCK KDLATEPQR-AVSVEP--------LDVPKFTLAVVVLTLAGFAVTSLLGF
Mvan_5336|M.vanbaalenii_PYR-1 KDLAVEPRR-AAVTEP--------VEVPVFALVVLGLTLLGFAVTSLLGL
TH_3461|M.thermoresistible__bu ADLSPAPSTGDRPAEP--------VGVPVFVLTVLGLTLTGFAVTSWLGI
. : *: .: * :
Rv2684|M.tuberculosis_H37Rv QPSLVALLGAGMLIVVSGLTRSEYLSSVEWDTLLFFAGLFIMVGALVKTG
Mb2703|M.bovis_AF2122/97 QPSLVALLGAGMLIVVSGLTRSEYLSSVEWDTLLFFAGLFIMVGALVKTG
MLBr_01036|M.leprae_Br4923 GPSLVGMLGAGILIVISKLERSDYLSSVKWETLLFFAGLFIMVGALVKTD
MMAR_2029|M.marinum_M QPSVVALLGAGVLIIISGLGGRDYLASVEWETLLFFAGLFIMVGALVKTG
MAV_3579|M.avium_104 EPSLVALLGAGILVVASRLQPADYLSGVEWDTLLFFAGLFVMVGALVKTG
MUL_3321|M.ulcerans_Agy99 KPSMVALIGAGILVVVSRLDHSDYLSSVEWDTLLFFVGLFIMVGALVKTG
MSMEG_0851|M.smegmatis_MC2_155 APSIVALLGAGVMLLVTDVDINEVLPEVEWPTLVFFMGLFVMVAGLTHTG
Mflv_1448|M.gilvum_PYR-GCK SPAWAALAGALVLGVRALADRRTTMSRIVVSLDIPFLIFVLCLGVVVDAV
Mvan_5336|M.vanbaalenii_PYR-1 SPAWAALAGALVLGVRALATRHTTVTRIAAAADVPFLIFVLCLGVVVAAV
TH_3461|M.thermoresistible__bu APAWAALAGALVLGVHGLARGRTTAEGVLSAANLPFLAFVVCLGIVVEAV
*: ..: ** :: : : : * :.: :. :. :
Rv2684|M.tuberculosis_H37Rv VVNDLARAATQLTG-GNIVATAFLILGVSAPISGIIDNIPYVATMTPLVA
Mb2703|M.bovis_AF2122/97 VVNDLARAATQLTG-GNIVATAFLILGVSAPISGIIDNIPYVATMTPLVA
MLBr_01036|M.leprae_Br4923 VVNQLARATTTLTG-GHELLTVVLTLGVSTLVSSIIDNIPYVATMTPIVS
MMAR_2029|M.marinum_M VVDKLARASIELTG-GNELFTVLLIIGVSAPVSGIIDNIPYVATMTPIVT
MAV_3579|M.avium_104 VVKHLARLAITATG-GNTLTATMVILVASVVISGIVDNVPYAATMAPVVA
MUL_3321|M.ulcerans_Agy99 VVTQVAQMAVTATG-GNTLLATMVILASSLVISGIVNNVPYAATMTPIVA
MSMEG_0851|M.smegmatis_MC2_155 VIGELGSVAQSAFG-DNWLGAATALLFGSSIAGAFIDNIPYTATMTPVVE
Mflv_1448|M.gilvum_PYR-GCK MRNGLESAMQQVIPDGHGLLALLGIAAVAALLSNVVNNLPAVLVLLPLVA
Mvan_5336|M.vanbaalenii_PYR-1 MRNGLESAMRDAIPEGQGLAALLGIAAVAAVLSNVVNNLPAVLVLLPLVT
TH_3461|M.thermoresistible__bu RTAGLDGALAAVLPDPGSLWGLLGIAAAAAVLANAVNNLPAVLALLPLVS
: : : . ::*:* . .: *:*
Rv2684|M.tuberculosis_H37Rv ELVAVMGGQPSTDTPWWALALGADFGGNLTAIGASANVVMLGIARRAGAP
Mb2703|M.bovis_AF2122/97 ELVAVMGGQPSTDTPWWALALGADFGGNLTAIGASANVVMLGIARRAGAP
MLBr_01036|M.leprae_Br4923 ELVASMPDQSHTDILWWALALGADFGGNLTAVGASANVVMLEIAKSAGTP
MMAR_2029|M.marinum_M ELVAVMPGQVNPDALWWALALGADFGGNLTAVGASANVVMLGIARRAGTP
MAV_3579|M.avium_104 DLVPALGDHANPAVLWWSLALGTDFGGNLTAIGASANIVLLGIARRADNP
MUL_3321|M.ulcerans_Agy99 ELVPVLVDKGNPDVLWWALALGTDFGGDLTAIGASANVIVLGIAKRADNP
MSMEG_0851|M.smegmatis_MC2_155 SMVADAPDMVTGNALWWAFALGACFSGNGTAIAASANVVAIGIAKRAGHP
Mflv_1448|M.gilvum_PYR-GCK GSGPAA---------VLAVLIGVNIGPNLTYVGSLANLLWRSVVR-RDVK
Mvan_5336|M.vanbaalenii_PYR-1 PIGPAA---------VLAVLIGVNIGPNLTYVGSLANLLWRSVVR-RDMR
TH_3461|M.thermoresistible__bu AAGPAA---------VLAVLIGVNIGPNLSYLGSLSNLLWRNAVQ-PDIP
. :. :*. :. : : :.: :*:: .: .
Rv2684|M.tuberculosis_H37Rv ISFWEFTRKGAVVTAVSIALAAIYLWLRYFVLLH
Mb2703|M.bovis_AF2122/97 ISFWEFTRKGAVVTAVSIALAAIYLWLRYFVLLH
MLBr_01036|M.leprae_Br4923 ISFWEFTRKGIAVTVISIALAGIYLWLRYLVMS-
MMAR_2029|M.marinum_M ISFWEFTRKGIVVTTISLLVAAAYLWLRYFVWS-
MAV_3579|M.avium_104 ISFWEFTRKGVVVTAVSVALSALYLWLRYFVWG-
MUL_3321|M.ulcerans_Agy99 ISFWEFTRKGIVVTTMSLVLAAIYLWVRYFVLS-
MSMEG_0851|M.smegmatis_MC2_155 ISFWQFTRYGIVVTFLSTALAWVYVWLRYF----
Mflv_1448|M.gilvum_PYR-GCK AGFGEFSRIGVVTTPLVLVAAVLGLWTYVRLIGL
Mvan_5336|M.vanbaalenii_PYR-1 VGFAEFSRAGLVTAPLTLVAAVLGLWAWIQLFGL
TH_3461|M.thermoresistible__bu AGFGEFSRIGLMTAPLTLVASVLALWVSLQLFGT
.* :*:* * .: : : :*