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LTLTVALLLLAVVLAFAVARPRGWPEAVAAVPAAGILIAMGAISPQQAAAQVSGLAGMVAFLGAVLVLAK LCDDEGLSEAAGAAMARSSPSSHGLLGQVFVVAALITAALSLDATVVLLTPVVLATVRRLRTPVRPYAYA TAHLANAASPLLPVSNLTNLLAYRGADISFTKFTLVMTLPWLLAIAAVYVILCWFFARDLVAEPNREHVG PPPRPPVFVLVVVALTLVGFATAESLGVAPAWAALAGASVLAVRSLRHRHTSVIEIARSANVSFLVFVLA LGVVVQAVMLSGIADKMSAVVPSGSGLTALLVIATVAALLANVVNNLPTTLVLMPLVAGNGPAAVLAVLI GVNIGPNLTYVGSLSNLLWRRVLRQHNVEAGVSEYTRLGLCTVPVSLVAAVIGLWVSVRLLGL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_4154 | arsB2 | - | 100% (413) | arsenical pump integral membrane protein ArsB2 |
| M. ulcerans Agy99 | MUL_3321 | arsA | 9e-25 | 24.58% (419) | arsenic-transport integral membrane protein ArsA |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3609 | arsB2 | 1e-177 | 78.45% (413) | arsenical PUMP integral membrane protein ArsB2 |
| M. gilvum PYR-GCK | Mflv_1448 | - | 1e-126 | 59.18% (414) | arsenical pump membrane protein |
| M. tuberculosis H37Rv | Rv3578 | arsB2 | 1e-177 | 78.69% (413) | arsenical PUMP integral membrane protein ArsB2 |
| M. leprae Br4923 | MLBr_01036 | - | 2e-20 | 21.55% (427) | putative membrane transport protein |
| M. abscessus ATCC 19977 | MAB_3634c | - | 1e-08 | 24.56% (395) | putative gluconate permease |
| M. marinum M | MMAR_5078 | arsB2 | 0.0 | 98.06% (413) | arsenical pump integral membrane protein ArsB2 |
| M. avium 104 | MAV_0577 | - | 1e-164 | 73.30% (412) | arsenical pump membrane protein |
| M. smegmatis MC2 155 | MSMEG_6072 | - | 1e-128 | 59.32% (413) | citrate transporter |
| M. thermoresistible (build 8) | TH_3461 | - | 1e-121 | 57.97% (414) | PUTATIVE putative Arsenical pump membrane protein |
| M. vanbaalenii PYR-1 | Mvan_5336 | - | 1e-133 | 61.59% (414) | arsenical pump membrane protein |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_4154|M.ulcerans_Agy99 -------------------MTLTVALLLLAVVLAFAVARPRGWPEAVAAV
MMAR_5078|M.marinum_M -------------------MTLTVALLLLAVVLAFAVARPRGWPEAVAAV
Mb3609|M.bovis_AF2122/97 -------------------MTLAVALILLAVVLGFAVARPRGWPEAAAAV
Rv3578|M.tuberculosis_H37Rv -------------------MTLAVALILLAVVLGFAVARPRGWPEAAAAV
MAV_0577|M.avium_104 -------------------MALTVALVLLAVVLGFAVARPRGWPEAVAAV
Mflv_1448|M.gilvum_PYR-GCK -------------------MALTLSVAALAAVLACALLRPR--LQAIVAG
Mvan_5336|M.vanbaalenii_PYR-1 -------------------MELILSVAALASVLAFALLRPHRWPEAVIAV
TH_3461|M.thermoresistible__bu -------------------MAVTVASAALIAVLVSALTRPRGWPEAVVAV
MSMEG_6072|M.smegmatis_MC2_155 -----MAAQRPLDRDRERALALTLALIALIVVLTFAMVRPNGWPEAVAAV
MLBr_01036|M.leprae_Br4923 ----------------------MSVIAITVFIVTYALIASDRVNKTLAAL
MAB_3634c|M.abscessus_ATCC_199 MNAGLVLLAEQANVAHTTSEVRLLAAVLLSIGAIILLITRLRLHPFLALL
:
MUL_4154|M.ulcerans_Agy99 PAAGILIAMGAISPQQAAAQVSG-----LAGMVAFLGAVLVLAKLCDDEG
MMAR_5078|M.marinum_M PAAGILIAMGAISPQQAAAQVSG-----LAGVVAFLGAVLVLAKLCDDEG
Mb3609|M.bovis_AF2122/97 PAAVILLAIGAISPQQAMAQVSG-----LARVVAFLGAVLVLAKLCDDEG
Rv3578|M.tuberculosis_H37Rv PAAVILLAIGAISPQQAMAQVSG-----LARVVAFLGAVLVLAKLCDDEG
MAV_0577|M.avium_104 PAALLLVGVGAIPVAAAEQQIAD-----LSGVVAFLGAVLVLAKLCDDEG
Mflv_1448|M.gilvum_PYR-GCK LAAALVIVAGATTWRAAVGEISE-----LAPVVAFLAAVLVLARLCDDEG
Mvan_5336|M.vanbaalenii_PYR-1 PAAALVIASGAISWDDALAEVGR-----LAPVVGFLAAVLVLARLCDDVG
TH_3461|M.thermoresistible__bu PAAALVVLTGAIALPDALAVADR-----LLPVVGFLAAVLVLARLCDDEG
MSMEG_6072|M.smegmatis_MC2_155 PAAVLLIALGAISVHDAVDEAGR-----LLPVVGFLAAVLVLAHLCDDEG
MLBr_01036|M.leprae_Br4923 TGAAIVVTLPIINSEDVFYSHETGI---DWEVIFLLLSMMIIVSVLRQTG
MAB_3634c|M.abscessus_ATCC_199 LGSGTLAAAASVPFDKLLGSFVTGFGSTIAGVGLLIGLGAMLGRLLADSG
.: : : :: :: : : *
MUL_4154|M.ulcerans_Agy99 LSEAAGAAMARSSPS-SHGLLGQVFVVAALITAALSLDATVVLLTPVVLA
MMAR_5078|M.marinum_M LFEAAGAAMARSSRS-SHGLLGQVFVVAALITAALSLDATVVLLTPVVLA
Mb3609|M.bovis_AF2122/97 LFEAAGAAMARASAE-SHRLLRQVFAVSAAITAALCLDATVVLLTPVVLA
Rv3578|M.tuberculosis_H37Rv LFEAAGAAMARASAE-SHRLLRQVFAVSAAITAALCLDATVVLLTPVVLA
MAV_0577|M.avium_104 LFEAAGAAIARGRVG-SAGMLRRVFVIASAITAVLSLDAAVVLLTPVVLA
Mflv_1448|M.gilvum_PYR-GCK LFRAAGTLMARATSGGQSRLLTTVFAISAAVTAILSLDATVILLTPVVLA
Mvan_5336|M.vanbaalenii_PYR-1 LFHTAGVMMARATSGGQIRLLASVFAIAAGVTAILSLDATVVLLTPVVLA
TH_3461|M.thermoresistible__bu LFRAAGAAMARVSSGNPVRLLAMVFVVAAATTAILSLDATAVLLTPVVLA
MSMEG_6072|M.smegmatis_MC2_155 LFHAAGTLMARASRGHPRKLLLRVFVIGATTTAVLSLDATVVLLTPVVLA
MLBr_01036|M.leprae_Br4923 VFEYVAIWTAKRSHGSPLRILLLLVLVMALGSALLDNVTTVLLIAPVTLL
MAB_3634c|M.abscessus_ATCC_199 GANIVADAVLTRSSP--RLLPWAVASIAAVLGLPLFFEVGVVLLIPIVLL
. .. : : : : * . .:*: *:.*
MUL_4154|M.ulcerans_Agy99 TVRRLRTPVRPYAYATAHLANAASPLLPVSN--LTNLLAYRGADISFTKF
MMAR_5078|M.marinum_M TVRRLRTPVRPYAYATAHLANAASLLLPVSN--LTNLLAYRGADISFTKF
Mb3609|M.bovis_AF2122/97 TVRRLRTPVRPYAYATAHLANAASLLLPVSN--LTNLLAYHGAGISFTKF
Rv3578|M.tuberculosis_H37Rv TVRRLRTPVRPYAYATAHLANAASLLLPVSN--LTNLLAYHGAGISFTKF
MAV_0577|M.avium_104 AVRRQRTAVRPYAYATAHLANGASLLLPVSN--LTNLLAFHTAQLSFTRF
Mflv_1448|M.gilvum_PYR-GCK TARALAVPARPHAYATAHLANSASLLLPVSN--LTNLLAFSAAGLSFLHF
Mvan_5336|M.vanbaalenii_PYR-1 TARTLAVPPRPHAYATAHLANSASLLLPVSN--LTNLLAFGAAGLSFLHF
TH_3461|M.thermoresistible__bu TARRLGVAPRPHAYATAHLANSASLLLPVSN--LTNLLAFGVCGLSFTRF
MSMEG_6072|M.smegmatis_MC2_155 TARTLAIAPRPHAYASAHLANSASLLFPVSN--LTNLLAFTVAGLSFVEF
MLBr_01036|M.leprae_Br4923 VCERLTINAAPFLMAEVFASNIGGAATLVGD--PPNIIIASRAGFSFNDF
MAB_3634c|M.abscessus_ATCC_199 VARRGNVPLLRVGIPALAGLSVLHGLVPPHPGPLVAVDALKADLGVTLAF
. . . . : *
MUL_4154|M.ulcerans_Agy99 TLVMTLPWLLAIAAVYVILCWFFARDLVA----EPNR-EHVGPPPR----
MMAR_5078|M.marinum_M TLVMTLPWLLAIAAVYVIFRWFFARDLVA----EPNR-EHVGPPPR----
Mb3609|M.bovis_AF2122/97 TLLMALPWLSAVAAVYVVFRWFFARDLRV----VPDR-QQLKPAPR----
Rv3578|M.tuberculosis_H37Rv TLLMALPWLSAVAAVYVVFRWFFARDLRV----VPDR-QQLKPAPR----
MAV_0577|M.avium_104 TLLMAAPWLAAVATLYAVFRGFFAKDLRV----QPDP-AALGAPPR----
Mflv_1448|M.gilvum_PYR-GCK AAAMTLPWIAAIVVEFLLLRWLFAKDLAT----EPQR-AVSVEPLD----
Mvan_5336|M.vanbaalenii_PYR-1 AAAMSLPWLAAIAVEFVLLRWFFAKDLAV----EPRR-AAVTEPVE----
TH_3461|M.thermoresistible__bu TALMTLPWLAAIACEFVLLRRLFRADLSP----APSTGDRPAEPVG----
MSMEG_6072|M.smegmatis_MC2_155 SAYMAIPWLAAVAVEFALLSWLFSAELRP----RPVP-ETAPPPPE----
MLBr_01036|M.leprae_Br4923 LIHLTPIVIIVTVVLSALLPRLFRGAFAV----DPERVADIMSLNEREAI
MAB_3634c|M.abscessus_ATCC_199 GLVAAVPTLIVAGPLYARIAERWVGPLDIPTATAPEAERTGPAPSVVAVL
: : . : : : *
MUL_4154|M.ulcerans_Agy99 ----PPVFVLVVVALTLVGFATAESLG------VAPAWAALAGASVLAVR
MMAR_5078|M.marinum_M ----PPVFVLVVVALTLVGFATAESLG------VAPAWAALAGASVLAVR
Mb3609|M.bovis_AF2122/97 ----LPMFVLVVVALTLGGFAVAESVG------LAPTWAALAGAAVLALR
Rv3578|M.tuberculosis_H37Rv ----LPMFVLVVVALTLGGFAVAESVG------LAPTWAALAGAAVLALR
MAV_0577|M.avium_104 ----PPVFVLVVVALTLAGFAVAQSVG------IAPAWVALCGASVLAVR
Mflv_1448|M.gilvum_PYR-GCK ----VPKFTLAVVVLTLAGFAVTSLLG------FSPAWAALAGALVLGVR
Mvan_5336|M.vanbaalenii_PYR-1 ----VPVFALVVLGLTLLGFAVTSLLG------LSPAWAALAGALVLGVR
TH_3461|M.thermoresistible__bu ----VPVFVLTVLGLTLTGFAVTSWLG------IAPAWAALAGALVLGVH
MSMEG_6072|M.smegmatis_MC2_155 ----VPVFVLVVLGLTLVGFAVTSLLD------LAPAWAALAGAVVLGIR
MLBr_01036|M.leprae_Br4923 RDRWLLIKCGVVLLLVFVAFIAHPVLH------TGPSLVGMLGAGILIVI
MAB_3634c|M.abscessus_ATCC_199 ATILLPVTLMLAKALSDVVIDNPKSLVQRIFDTIGTPLVALLAATLVAMV
. * : : ... ..: .* :: :
MUL_4154|M.ulcerans_Agy99 SLRHRH----TSVIEIARSANVSFLVFVLALG-------VVVQAVMLSGI
MMAR_5078|M.marinum_M SLRHRH----TSVIEIARSANVSFLVFVLALG-------VVVQAVMLSGI
Mb3609|M.bovis_AF2122/97 SLRRGH----TSVLRIARAVNVSFLVFVLALG-------VVVHAVMLNGM
Rv3578|M.tuberculosis_H37Rv SLRRGH----TSVLRIARAVNVSFLVFVLALG-------VVVHAVMLNGM
MAV_0577|M.avium_104 SLARGH----TTVTEIARSVHVSFLVFVLALG-------VVVQAVMRNGM
Mflv_1448|M.gilvum_PYR-GCK ALADRR----TTMSRIVVSLDIPFLIFVLCLG-------VVVDAVMRNGL
Mvan_5336|M.vanbaalenii_PYR-1 ALATRH----TTVTRIAAAADVPFLIFVLCLG-------VVVAAVMRNGL
TH_3461|M.thermoresistible__bu GLARGR----TTAEGVLSAANLPFLAFVVCLG-------IVVEAVRTAGL
MSMEG_6072|M.smegmatis_MC2_155 SFAQRR----STVRGIVRAVNVPFLAFVLCLG-------VVVDAVVLNGP
MLBr_01036|M.leprae_Br4923 SKLERS----DYLSSVKWETLLFFAGLFIMVG-------ALVKTDVVNQL
MAB_3634c|M.abscessus_ATCC_199 TLGKASGLDRIGVAGIIEKSLGPIAGIVFIVGAGGGFKQTLIDVGVGDAV
: : :.. :* :: .
MUL_4154|M.ulcerans_Agy99 ADKMSAVVPSGSGLTALLVIATVAALLANVVNNLPTTLVLMPLVAGNGP-
MMAR_5078|M.marinum_M ADKMSAVVPSGSGLTALLVIATVAALLANVVNNLPATLVLMPLVAGNGP-
Mb3609|M.bovis_AF2122/97 AARMSAVLPTGSGLPALLGIAALASVLANVVNNLPATLVLVPLVAAGGP-
Rv3578|M.tuberculosis_H37Rv AARMSAVLPTGSGLPALLGIAALAAVLANVVNNLPATLVLVPLVAAGGP-
MAV_0577|M.avium_104 DRAMSALLPSGSGLPALLAIAATAAVLANVVNNLPATLVLLPLVAPAGP-
Mflv_1448|M.gilvum_PYR-GCK ESAMQQVIPDGHGLLALLGIAAVAALLSNVVNNLPAVLVLLPLVAGSGP-
Mvan_5336|M.vanbaalenii_PYR-1 ESAMRDAIPEGQGLAALLGIAAVAAVLSNVVNNLPAVLVLLPLVTPIGP-
TH_3461|M.thermoresistible__bu DGALAAVLPDPGSLWGLLGIAAAAAVLANAVNNLPAVLALLPLVSAAGP-
MSMEG_6072|M.smegmatis_MC2_155 EAVMRDVLPDGDSLPALLGYAAIAAVLANLVNNLPAVLMLLPLVAAAGP-
MLBr_01036|M.leprae_Br4923 ARATTTLTG-GHELLTVVLTLGVSTLVSSIIDNIPYVATMTPIVSELVAS
MAB_3634c|M.abscessus_ATCC_199 SSWSEKWQIPALVLGWLIAVLIRLATGSATVATITAAGIVSPLAADMST-
* :: : : : .:. . : *:.: .
MUL_4154|M.ulcerans_Agy99 --------AAVLAVLIGVNIGPNLTYVGSLSNLLWRRVLRQHNVEAGVSE
MMAR_5078|M.marinum_M --------AAVLAVLIGVNIGPNLTYVGSLSNLLWRRVLRQHNVEAGVSE
Mb3609|M.bovis_AF2122/97 --------AAVLAVLLGVNIGPNLTYAGSLSNLLWRGVLRRHNVDASVGE
Rv3578|M.tuberculosis_H37Rv --------AAVLAVLLGVNIGPNLTYAGSLSNLLWRGVLRRHNVDASVGE
MAV_0577|M.avium_104 --------VAVLAVLIGVNIGPNLTYVGSLSNLLWRRVLRQHGVDAGVGE
Mflv_1448|M.gilvum_PYR-GCK --------AAVLAVLIGVNIGPNLTYVGSLANLLWRSVVRRD-VKAGFGE
Mvan_5336|M.vanbaalenii_PYR-1 --------AAVLAVLIGVNIGPNLTYVGSLANLLWRSVVRRD-MRVGFAE
TH_3461|M.thermoresistible__bu --------AAVLAVLIGVNIGPNLSYLGSLSNLLWRNAVQPD-IPAGFGE
MSMEG_6072|M.smegmatis_MC2_155 --------GAVLAVLIGVNVGPNLTYVGSLSNLLWRHVVHRQGLAAKAGE
MLBr_01036|M.leprae_Br4923 MPDQSHTDILWWALALGADFGGNLTAVGASANVVMLEIAKSAGTPISFWE
MAB_3634c|M.abscessus_ATCC_199 ----------AHVALLVLAVGAGSLFFSHVNDAGFWLVKEYFGMSVG-QT
. : .* . . : .
MUL_4154|M.ulcerans_Agy99 YTRLGLCTVPVSLVAAVIGLWVSVRLLGL
MMAR_5078|M.marinum_M YTRLGLCTVPVALVAAVIGLWVSVRLLGL
Mb3609|M.bovis_AF2122/97 YTRLGLCTVPAALAMAVLALWASAQVLGI
Rv3578|M.tuberculosis_H37Rv YTRLGLCTVPAALAMAVLALWASAQVLGI
MAV_0577|M.avium_104 YTRLGVCTVPVSLLVAVLALWASARLLGG
Mflv_1448|M.gilvum_PYR-GCK FSRIGVVTTPLVLVAAVLGLWTYVRLIGL
Mvan_5336|M.vanbaalenii_PYR-1 FSRAGLVTAPLTLVAAVLGLWAWIQLFGL
TH_3461|M.thermoresistible__bu FSRIGLMTAPLTLVASVLALWVSLQLFGT
MSMEG_6072|M.smegmatis_MC2_155 FSRVGVVTTPLTLVAAVLGLWAGLELFG-
MLBr_01036|M.leprae_Br4923 FTRKGIAVTVISIALAGIYLWLRYLVMS-
MAB_3634c|M.abscessus_ATCC_199 LKSWSVMETLISVVGFAMVLLLSVVV---
. .: . : : * :