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MAQLTALDAGFLKSRDPERHPGLAIGAVAVVNGAAPSYDQLKTVLTERIKSIPRCTQVLATEWIDYPGFD LTQHVRRVALPRPGDEAELFRAIALALERPLDPDRPLWECWIIEGLNGNRWAILIKIHHCMAGAMSAAHL LARLCDDADGSAFANNVDIKQIPPYGDARSWAETLWRMSVSIAGAVCTAAARAVSWPAVTSPAGPVTTRR RYQAVRVPRDAVDAVCHKFGVTANDVALAAITEGFRTVLLHRGQQPRADSLRTLEKTDGSSAMLPYLPVE YDDPVRRLRTVHNRSQQSGRRQPDSLSDYTPLMLCAKMIHALARLPQQGIVTLATSAPRPRHQLRLMGQK MDQVLPIPPTALQLSTGIAVLSYGDELVFGITADYDAASEMQQLVNGIELGVARLVALSDDSVLLFTKDR RKRSSRALPSAARRGRPSVPTARARH
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3371 | - | - | 100% (446) | hypothetical protein Rv3371 |
| M. tuberculosis H37Rv | Rv3130c | tgs1 | 5e-97 | 44.97% (447) | triacylglycerol synthase |
| M. tuberculosis H37Rv | Rv1425 | - | 1e-33 | 26.80% (459) | hypothetical protein Rv1425 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3406 | - | 0.0 | 99.55% (446) | hypothetical protein Mb3406 |
| M. gilvum PYR-GCK | Mflv_4977 | - | 1e-100 | 44.07% (447) | hypothetical protein Mflv_4977 |
| M. leprae Br4923 | MLBr_01244 | - | 1e-13 | 33.33% (108) | hypothetical protein MLBr_01244 |
| M. abscessus ATCC 19977 | MAB_0507 | - | 5e-32 | 27.21% (463) | hypothetical protein MAB_0507 |
| M. marinum M | MMAR_1157 | - | 1e-147 | 61.64% (451) | hypothetical protein MMAR_1157 |
| M. avium 104 | MAV_4336 | - | 1e-121 | 53.19% (455) | acyltransferase, ws/dgat/mgat subfamily protein |
| M. smegmatis MC2 155 | MSMEG_5242 | - | 1e-96 | 44.47% (443) | acyltransferase, ws/dgat/mgat subfamily protein |
| M. thermoresistible (build 8) | TH_2686 | - | 3e-35 | 27.53% (454) | PUTATIVE Diacylglycerol O-acyltransferase |
| M. ulcerans Agy99 | MUL_2420 | - | 4e-98 | 45.29% (446) | hypothetical protein MUL_2420 |
| M. vanbaalenii PYR-1 | Mvan_4104 | - | 7e-96 | 44.35% (451) | hypothetical protein Mvan_4104 |
CLUSTAL 2.0.9 multiple sequence alignment
Rv3371|M.tuberculosis_H37Rv -------MAQLTALDAGFLKSRDPERHPGLAIGAVAV-VNGAAPSYDQLK
Mb3406|M.bovis_AF2122/97 -------MAQLTALDAGFLKSRDPERHPGLAIGAVAV-VNGAAPSYDQLK
MMAR_1157|M.marinum_M ------MIAQLTTLDAGLRRAQEPDWDASLAIGAVAV-INGAVPDFELLK
MAV_4336|M.avium_104 -------MAQT--LDTAFLKAHDPDQHASLAIGAVAI-VDGTVPDPAQLE
Mflv_4977|M.gilvum_PYR-GCK -------MERMTAFDAGFLDAEDADRHVSLAVGAVSV-VDGPMPDFDEIV
Mvan_4104|M.vanbaalenii_PYR-1 -------MEHLSTLDASFLQAEDSDPHVSLAVGAVSI-IEGPAPDYDDLV
MSMEG_5242|M.smegmatis_MC2_155 ----MTAPEQLSVLDAGFLEAEDSDPNVSLAIGAVAV-MAGPMPDFETLK
MUL_2420|M.ulcerans_Agy99 -------MNHLTTLDSGFLKAEDVDPRVSLAIGGLAV-IEGPVPEQHDLV
TH_2686|M.thermoresistible__bu ------MVTRLSASDADFFHLEDTSTPMYVGSLAILR-RPRGGLSYETLL
MAB_0507|M.abscessus_ATCC_1997 -------MQRLSGVDAAFWHAETAGWHMHIGGLSIYDPTDAPDYSFERVR
MLBr_01244|M.leprae_Br4923 MADSVEGIGPFDELGALDYLLHRGEANPRTRAGIMAVELLDTTPDWNRFR
.: . : . .
Rv3371|M.tuberculosis_H37Rv TVLTERIKSIPRCTQVLAT--------EWIDYPGFDLTQHVRRVALPRPG
Mb3406|M.bovis_AF2122/97 TVLTERIKSIPRCTQVLAT--------EWIDYPGFDLTQHVRRVALPRPG
MMAR_1157|M.marinum_M TTLAQRLRSIPRHAQVLRT--------QWIDQPEFDFDAHIQRAALPGPG
MAV_4336|M.avium_104 HLVAERILPIARCTQLLRAHPLNR---EWVDCPDFDLAWHLRRVAIAGTG
Mflv_4977|M.gilvum_PYR-GCK AAIGEKIVTIPRLRQVVRRQPLDLSAPEWVEDPTLDLAHHIRRAALPHPG
Mvan_4104|M.vanbaalenii_PYR-1 AAFAERAQGIPRCTQIVHTRPFDLAAPEWVDDPHFDIAHHLHRIALPAPG
MSMEG_5242|M.smegmatis_MC2_155 ATLAERILSVPRLRQVLHTRPLDLGAPEWVDDPHLDITRHIRRAALPRPG
MUL_2420|M.ulcerans_Agy99 SVFSERIRACPRFAQRLRRYPFDLGAPQWVDDPDFDIARHVRRVALPHPG
TH_2686|M.thermoresistible__bu ATVEQRLPQIPRYRQKVRKAPIGLARPVWVDDPDFDITYHVRRSALPSPG
MAB_0507|M.abscessus_ATCC_1997 ALIVERLPSMPQLRWRVTDVPLGLDRPWFVEDEELDPDFHIRRIGVPAPG
MLBr_01244|M.leprae_Br4923 SRIEDVSQRVLRLRQKVVVPTLPTAAPRWVVDPDFELDFHVRRVRVPDPG
. : : : :: :: *::* :. .*
Rv3371|M.tuberculosis_H37Rv DEAELFRAIALALERPLDPDRPLWECWIIEGLNGNRWAILIKIHHCMAGA
Mb3406|M.bovis_AF2122/97 DEAELFRAIALALERPLDPDRPLWECWIIEGLNGNRWAILIKIHHCMAGA
MMAR_1157|M.marinum_M DEAELFRAIAHALERPLDLDRPLWECWVIEGLEHNRWAILLKLHHSMADG
MAV_4336|M.avium_104 DEAELSRVIGQALRRPLDPGRPPWECWVIEGLRGNRWAMLMKTHHGLLDG
Mflv_4977|M.gilvum_PYR-GCK DDDALFRFTAEAMEPRLDRERPLWQAWIIEGLADDRWAILMKVHHCIADG
Mvan_4104|M.vanbaalenii_PYR-1 DDAEMFTTIAGIMERRLDRDRPLWECWIIEGLADGRWATLMKIHHCIADG
MSMEG_5242|M.smegmatis_MC2_155 DDAALHDWVAEVMERRLDRDHPLWQCWVADGLPANRWAILIKIHHCVADG
MUL_2420|M.ulcerans_Agy99 DDDALYRLVADVMGRRLDRDRPLWELWVIEGLAGERWAMLTKVHHCMADG
TH_2686|M.thermoresistible__bu SDAQLHELIARLASRPLDKTRPLWEMYLIEGLAKNRLALYTKSHQALVNG
MAB_0507|M.abscessus_ATCC_1997 GRKELEELAGRLMSYKLDRSRPLWELWVIEGVEGGRVATLTKMHHAIVDG
MLBr_01244|M.leprae_Br4923 TLREVFDLAEVIQQSPMDVSRPLWTATLVEGLAAGRAAMLLQISHAITDG
: :* :* * : :*: * * : : : ..
Rv3371|M.tuberculosis_H37Rv MSAAHLLARLCDDADGSAFANNVDIKQIP-PY-----------------G
Mb3406|M.bovis_AF2122/97 MSAAHLLARLCDDADGSAFANNVDIKQIP-PY-----------------G
MMAR_1157|M.marinum_M ISAVQILTRLCDDADHTG-VNHVAVKPVPDSD-----------------A
MAV_4336|M.avium_104 NPAARLITRLCDDADADMFANNAAAQPVS---------------------
Mflv_4977|M.gilvum_PYR-GCK IAAMHMLAGLSDDGEGETYAGAIRAAHEAGASRPALPS---------PTL
Mvan_4104|M.vanbaalenii_PYR-1 IATAQMLAKLSDDGAGETFAADIRAAQESGPSILGLLR---------PRL
MSMEG_5242|M.smegmatis_MC2_155 VAAAHLLTRLCDDSPEPSVPHAPPPAPRQAP----------------FSL
MUL_2420|M.ulcerans_Agy99 IAATHILTGLCDRDGGGAADGSARCRAAQRPK-----T---------AAA
TH_2686|M.thermoresistible__bu MTAPEIGHVIADRTQKPPQFGEDIWMPGREPGTAQLLIG----AIGDWLT
MAB_0507|M.abscessus_ATCC_1997 VSGAGLGEILLDIAPEPRPAPDDTVGSLVGLGLPSRER------ILLSAL
MLBr_01244|M.leprae_Br4923 VGSVEMFAEMYDLERDPPSRPRSPQPIPQDLSRNDLMLQGINHLPVALAG
: : *
Rv3371|M.tuberculosis_H37Rv DARSWAETLWRMSVSIAGAVCTAAAR------AVSWP-AVTSPAGPVTT-
Mb3406|M.bovis_AF2122/97 DARSWAETLWRMSVSIAGAVCTAAAR------AVSWP-AVTSPAGPVTT-
MMAR_1157|M.marinum_M GARSWPD-------SLATNIVKAAAR------AVSWPTMWLSSADSPIT-
MAV_4336|M.avium_104 SPTGWLD---------ALSRVSSLTG------GLLGALRLAGRAEAVAP-
Mflv_4977|M.gilvum_PYR-GCK NPVRWARAGWNATTAVAATAAMTVEGAIGILSGLVR-NAESSLNGPVTT-
Mvan_4104|M.vanbaalenii_PYR-1 NPLDWMNGAWRATLAAAGAAEHAVVGAAELTARVLTPGQESSLNGPVTG-
MSMEG_5242|M.smegmatis_MC2_155 NPVDWVTGAWRTAMDVTGIAGKVLHGAGEIVSGLLT-PAPSSLTGPVTA-
MUL_2420|M.ulcerans_Agy99 RPRSGLSGLWNAPAAIASGVVRLAQGSGELVTGLLT-PVASALTGPLSD-
TH_2686|M.thermoresistible__bu RPGAQMIAVRDNVLGMATNAGELVDAGRRALSVARTVARGTAPSSPLNTR
MAB_0507|M.abscessus_ATCC_1997 VNVGVKTPYRVARLVQQTVRQQLAVFGMERKSPGYFEAPHTRFNAPVSP-
MLBr_01244|M.leprae_Br4923 GVVGGLSGVASVAGRAILRPASTVSGVVGYVRSGIRVLSQAAEPSPLLRQ
.
Rv3371|M.tuberculosis_H37Rv ---RRRYQAVRVPRDAVDAVCHKFGVTANDVALAAITEGFRTVLLHRGQQ
Mb3406|M.bovis_AF2122/97 ---RRRYQAVRVPRDAVDAVCHKFGVTANDVALAAITEGFRTVLLHRGQQ
MMAR_1157|M.marinum_M ---MRHYTAVRFALADVDRVCRKFGVTANDVALAAISEGFRTMLLHRGEQ
MAV_4336|M.avium_104 ---VRRYATVRVPIADVDRVCRKFGVSANDVALAAVTEGFRTVLLDRGEQ
Mflv_4977|M.gilvum_PYR-GCK ---MRRYSAVQVPLATVASVCQAFDVTLNDVALAAITDSFRSALKRRGEE
Mvan_4104|M.vanbaalenii_PYR-1 ---MRRYSAAVVDLAVMKQVSRNFDVTLNDVALAAITNGYRHMLLDRGES
MSMEG_5242|M.smegmatis_MC2_155 ---RRRFAAAEVSLADVARVCERFDVTVNDVALAAITASFRSMLIARGVA
MUL_2420|M.ulcerans_Agy99 ---LRRFSGARVPMADLELVCETFDVTINDVALAAITESYRNVLLARGQQ
TH_2686|M.thermoresistible__bu VSRNRRFTVARHRLDDYRKVRARYDCDVNDVVLAVIAGALRNWLLSRGEQ
MAB_0507|M.abscessus_ATCC_1997 ---HRRISGARLDLARVKALKDAFGVKVNDVVLAIVAGAVRDYLAKRDEF
MLBr_01244|M.leprae_Br4923 RSLATRTEAIEIQLSDLHKAAKAGDGSINDAYLAGLVGALRRYHEALGVS
: . **. ** : . * .
Rv3371|M.tuberculosis_H37Rv PR-ADSLRTLEK-----------------TDGSSAMLPYLPVEYDDPVRR
Mb3406|M.bovis_AF2122/97 PR-ADSLRTLEK-----------------TDGSSAMLPYLPVEYDDPVRR
MMAR_1157|M.marinum_M PR-ADSLRTLEKP----------------ANQISALLPYLPVDQNDPITR
MAV_4336|M.avium_104 PR-ADSLRTLVP-----------------LPVRSAVLSHLPVEHDDPVRR
Mflv_4977|M.gilvum_PYR-GCK PR-RDSLRTLVPVSVRS-----DDARDRLDNRVSVMLPHLPVDEPDPVEQ
Mvan_4104|M.vanbaalenii_PYR-1 PG-PHALRTLVPVSMRS-----AGDFDVTDNRVSAMLPLLPVDEPDPVRQ
MSMEG_5242|M.smegmatis_MC2_155 PG-PNALPTLVPVSVRPP----AGAGNDRANQVSVMLPNLPVDQADPVAQ
MUL_2420|M.ulcerans_Agy99 PQ-QGSLRTLVPVSVRA-----DNAFDKTDNRVSAMLPNLPVDEEDPVQR
TH_2686|M.thermoresistible__bu VSSTATVRAMAPLSVQSDAELDSTAPGQAVSDVVPFLIDLPVGERNPVVR
MAB_0507|M.abscessus_ATCC_1997 PD--KPLIVQIPVSVRT-----EETDGVVGNQVSSMTVSLATDIDDPAER
MLBr_01244|M.leprae_Br4923 IS---TLPMAVPVNVRT------EADVVGSNRFVGVTLAAPLGTNDPAAR
.: . . :* :
Rv3371|M.tuberculosis_H37Rv LRTVH---NRSQQSGRR----QPDSLSDYTPLMLCAKMIHALARLPQQG-
Mb3406|M.bovis_AF2122/97 LRTVH---NRSQQSGRR----QPDSLSDYTPLMLCAKMIHALARLPQQG-
MMAR_1157|M.marinum_M LRTVHSQLNPAPAAVRT----KSASLADYTPLALCTKAIQTLVRLPQRS-
MAV_4336|M.avium_104 LQTVHARCNPAAGTQPAG---IVESAIGLVPNMVRGNLIQLLSRLPQRA-
Mflv_4977|M.gilvum_PYR-GCK LRTVHRRLNRAKSSGQRQAGTAAVAAVKLIPFALATRAIRAVTSLPQHG-
Mvan_4104|M.vanbaalenii_PYR-1 LEIVHRRLSRAKGSGQREGGDAVLAAAGNIPFALSAWTIRLLTRLPQRS-
MSMEG_5242|M.smegmatis_MC2_155 LQAVHTRLSKAKASGQRQAGSALVTMAAAVPFPLTAWAVRALTRLPQRG-
MUL_2420|M.ulcerans_Agy99 LRKVHARLGQTKASGQPRAGNLFLSLADRIPFALTAWTVGVLMRLPQRG-
TH_2686|M.thermoresistible__bu LSQISHATETHPTASSLVDARTIVTLTGFAPATLHAMGVRVATNFSARQ-
MAB_0507|M.abscessus_ATCC_1997 IQAIYEGTQGAKEMARAMSAHQIMGLTDTTPPGLLQLAARAYTASGLSRN
MLBr_01244|M.leprae_Br4923 MQKIRSQMTQRRDEPAMNIIGSLAPLMTVLPASVLDFIVDSVASSDVNA-
: : * :
Rv3371|M.tuberculosis_H37Rv ---IVTLATSAPRPRHQLRLMGQKMDQVLPIPPTALQLSTGIAVLSYGDE
Mb3406|M.bovis_AF2122/97 ---IVTLATSAPGPRHQLRLMGQKMDQVLPIPPTALQLSTGVAVLSYGDE
MMAR_1157|M.marinum_M ---VVTLATDAPAPRHRLQLMGQPMEQVLPIPPTALQLSTGVAVLCYDDE
MAV_4336|M.avium_104 ---VVTLATNVPGPRRRLRVMGQTLERLLPVPPTATQLHTGVAVLSYGDE
Mflv_4977|M.gilvum_PYR-GCK ---VVTLATNVPGPQHRLQVMGREVVRMFPVPPMALRLRTAVAILSYGDD
Mvan_4104|M.vanbaalenii_PYR-1 ---VTALATNVPGPRGRQRVLGRKVVEILPIPPIALHLRTGIAMLSYAGR
MSMEG_5242|M.smegmatis_MC2_155 ---VAMLATNVPGPRRRVTILGREVIRLLPVPPIAMRMRTAVAILSYADH
MUL_2420|M.ulcerans_Agy99 ---VATVATNVPGPRQPLQIMGRPVAAVFPVPPLAMHLRTGVAMLSYSDD
TH_2686|M.thermoresistible__bu ---FNLLITNVPGAQKQMYIAGTKMLESYSVPPLLRNQVLAVAVTSYHGM
MAB_0507|M.abscessus_ATCC_1997 LAPINLVLSNVPGPSFPLYMAGARLESMIPLGPPVMDVALNITCFSYLEH
MLBr_01244|M.leprae_Br4923 --------SNIPAYPGDTYFAGAKILRQYGIGPRPG-VAMMAVLMSRGGF
:. * . * : : * . .
Rv3371|M.tuberculosis_H37Rv LVFGITADYDAASEMQQLVNGIELGVARLVALSDDSVLLFTKDRRKRSSR
Mb3406|M.bovis_AF2122/97 LVFGITADYDAASEMQQLVNGIELGVARLVALSDDSVLLFTKDRRKRSSR
MMAR_1157|M.marinum_M LVFGITADYQAATDLRQLAAGIERGMAQLVALSQDSVLLFGKDRRKRRHR
MAV_4336|M.avium_104 LVFGITAGPGDGFDVTRLAAAVELGMARLAALGDDSVLLFADRRRRRAAR
Mflv_4977|M.gilvum_PYR-GCK LVFGITTDFDAFPDVDELAAGIGAAVDTLAAAA--------RPL------
Mvan_4104|M.vanbaalenii_PYR-1 FSFGITADYDSAPDVDALARGIGEGVRCLAELG--------RAERRTPPD
MSMEG_5242|M.smegmatis_MC2_155 LAFGIISDYDAEIDVDAVAAGIEQAVARLAQIA--------VAHIRSTPL
MUL_2420|M.ulcerans_Agy99 LYFGILTDYNPVADVDQLARGTEAAVARLVAIS--------KRRKARRGR
TH_2686|M.thermoresistible__bu LYYGVNADRDAMSDVEVLPSLLSESLDELLEAAQ----------------
MAB_0507|M.abscessus_ATCC_1997 MDFGFVTTPEVAADIDEMADGLEAALVELEHAVGI---------------
MLBr_01244|M.leprae_Br4923 CTVTVRYDRASVKSEALFARCLLEGFDEVLALAGDPTPHAVPASFAARSS
. . . .. :
Rv3371|M.tuberculosis_H37Rv ALPSAARRGRPSVPTARARH
Mb3406|M.bovis_AF2122/97 ALPSAARRGRPSVPTARARH
MMAR_1157|M.marinum_M SRPGGVAR-RTLVSPARVRR
MAV_4336|M.avium_104 SPLGRVPPAHPSAP-GHARH
Mflv_4977|M.gilvum_PYR-GCK --------------------
Mvan_4104|M.vanbaalenii_PYR-1 GAGRPIADAP----------
MSMEG_5242|M.smegmatis_MC2_155 GTLALVPGELA---------
MUL_2420|M.ulcerans_Agy99 GPLSLVV-------------
TH_2686|M.thermoresistible__bu --------------------
MAB_0507|M.abscessus_ATCC_1997 --------------------
MLBr_01244|M.leprae_Br4923 GSPAGWLSSS----------