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MKRLSSVDAAFWSAETAGWHMHVGALAICDPSDAPEYSFQRLRELIIERLPEIPQLRWRVTGAPLGLDRP WFVEDEELDIDFHIRRIGVPAPGGRRELEELVGRLMSYKLDRSRPLWELWVIEGVEGGRIATLTKMHHAI VDGVSGAGLGEILLDITPEPRPPQQETVGFVGFQIPGLERRAIGALINVGIMTPFRIVRLLEQTVRQQIA ALGVAGKPARYFEAPKTRFNAPVSPHRRVTGTRVELARAKAVKDAFGVKLNDVVLALVAGAARQYLQKRD ELPAKPLIAQIPVSTRSEETKADVGNQVSSMTASLATHIEDPAKRLAAIHESTLSAKEMAKAPSAHQIMG LTETTPPGLLQLAARAYTASGLSHNLAPINLVVSNVPGPPFPLYMAGARLDSLVPLGPPVMDVALNITCF SYQDYLDFGLVTTPEVANDIDEMADAIEPALAELERAAE
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1425 | - | - | 100% (459) | hypothetical protein Rv1425 |
| M. tuberculosis H37Rv | Rv1760 | - | 6e-70 | 35.87% (460) | hypothetical protein Rv1760 |
| M. tuberculosis H37Rv | Rv3740c | - | 8e-67 | 39.25% (456) | hypothetical protein Rv3740c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1460 | - | 0.0 | 99.78% (459) | hypothetical protein Mb1460 |
| M. gilvum PYR-GCK | Mflv_0349 | - | 0.0 | 66.74% (457) | hypothetical protein Mflv_0349 |
| M. leprae Br4923 | MLBr_01244 | - | 7e-25 | 25.70% (393) | hypothetical protein MLBr_01244 |
| M. abscessus ATCC 19977 | MAB_0507 | - | 0.0 | 77.07% (458) | hypothetical protein MAB_0507 |
| M. marinum M | MMAR_2231 | - | 0.0 | 90.39% (458) | hypothetical protein MMAR_2231 |
| M. avium 104 | MAV_3352 | - | 0.0 | 86.36% (462) | acyltransferase, ws/dgat/mgat subfamily protein |
| M. smegmatis MC2 155 | MSMEG_4297 | - | 3e-88 | 42.03% (464) | acyltransferase, ws/dgat/mgat subfamily protein |
| M. thermoresistible (build 8) | TH_2477 | - | 1e-86 | 41.45% (468) | PUTATIVE acyltransferase, ws/dgat/mgat subfamily protein |
| M. ulcerans Agy99 | MUL_1818 | - | 0.0 | 90.39% (458) | hypothetical protein MUL_1818 |
| M. vanbaalenii PYR-1 | Mvan_3601 | - | 4e-87 | 41.85% (466) | hypothetical protein Mvan_3601 |
CLUSTAL 2.0.9 multiple sequence alignment
Rv1425|M.tuberculosis_H37Rv ---------------MKRLSSVDAAFWSAETAGWHMHVGALAICDPSDAP
Mb1460|M.bovis_AF2122/97 ---------------MKRLSSVDAAFWSAETAGWHMHVGALAICDPSDAP
MMAR_2231|M.marinum_M ---------------MRRLSSVDAAFWSAETAGWHMHVGALAICDPTDAP
MUL_1818|M.ulcerans_Agy99 ---------------MRRLSSVDAAFWSAETAGWHMHVGALAICDPTDAP
MAV_3352|M.avium_104 --------------MMKRLSSVDAAFWSAETAGWHMHVGALAICDPKGSA
MAB_0507|M.abscessus_ATCC_1997 ---------------MQRLSGVDAAFWHAETAGWHMHIGGLSIYDPTDAP
Mflv_0349|M.gilvum_PYR-GCK ----------------MRLSSVDAAFWFAENLKWHMHIGAIALCDPSDVP
MSMEG_4297|M.smegmatis_MC2_155 ---------------MQRLSGLDASFLYLETAAQPMHVCSVLELDTSTMP
Mvan_3601|M.vanbaalenii_PYR-1 MDLLTPAPPRHTIGGMQRLSGLDASFLYLESAAQPLHVCSILELDTSTMP
TH_2477|M.thermoresistible__bu ------VPPPYDRG-MQRLSGLDASFLYLETPDQPLHVCSILELDTSTIP
MLBr_01244|M.leprae_Br4923 -----MADSVEGIGPFDELGALDYLLHRGEANPR-TRAGIMAVELLDTTP
.*..:* : * : : .
Rv1425|M.tuberculosis_H37Rv -EYSFQRLRELIIERLPEIPQLRWRVTGAPLGLDRPWFVEDEELDIDFHI
Mb1460|M.bovis_AF2122/97 -EYSFQRLRELIIERLPEIPQLRWRVTGAPLGLDRPWFVEDEELDIDFHI
MMAR_2231|M.marinum_M -DYSFQRLRELLIERLPEIPQLRWRVTGAPLGLDRPWFVEDQDLDVDFHV
MUL_1818|M.ulcerans_Agy99 -DYSFQRLRELLIERLPEIPQLRWRVTGAPLGLDRPWFVEDQDLDVDFHV
MAV_3352|M.avium_104 -EYTFERLRQLLIERLPEVPQLRWRVTGAPLGLDRPWFVEDEELDVDFHL
MAB_0507|M.abscessus_ATCC_1997 -DYSFERVRALIVERLPSMPQLRWRVTDVPLGLDRPWFVEDEELDPDFHI
Mflv_0349|M.gilvum_PYR-GCK -DFGFEQVRDLIISRLPELPQLRWRVVGAPLGLDRPYFVEDEDIDVDFHI
MSMEG_4297|M.smegmatis_MC2_155 GGYTFDRLRDALSLRIKAMPEFREKLADSRFNLDHPVWVEDNDFDVDRHL
Mvan_3601|M.vanbaalenii_PYR-1 GGYTFDRLRDGLALRIKAMPEFREKIADSRFNLDHPVWVEDNDFDVDRHL
TH_2477|M.thermoresistible__bu GGYDFHQLREALLLRIKAMPEFREKLADNRFNLDHPVWVEDADFDVDRHL
MLBr_01244|M.leprae_Br4923 ---DWNRFRSRIEDVSQRVLRLRQKVVVPTLPTAAPRWVVDPDFELDFHV
:.:.* : : .:* ::. : * :* * ::: * *:
Rv1425|M.tuberculosis_H37Rv RRIGVPAPGGRRELEELVGRLMSYKLDRSRPLWELWVIEGVE------GG
Mb1460|M.bovis_AF2122/97 RRIGVPAPGGRRELEELVGRLMSYKLDRSRPLWELWVIEGVE------GG
MMAR_2231|M.marinum_M RRIGVPAPGGRRELEELVGRLMSYKLDRSRPLWELWVIEGVE------GG
MUL_1818|M.ulcerans_Agy99 RRIGVPAPGGRRELEELVGRLMSYKLDRSRPLWELWVIEGVE------GG
MAV_3352|M.avium_104 RRIGVPAPGGRRELEELVGRLMSYKLDRSRPLWEMWVIEGLDGN---AGG
MAB_0507|M.abscessus_ATCC_1997 RRIGVPAPGGRKELEELAGRLMSYKLDRSRPLWELWVIEGVE------GG
Mflv_0349|M.gilvum_PYR-GCK RRIAVPSPGGRKELDDLVGRLMSYKLDRSKPLWELWFIEGLE------GG
MSMEG_4297|M.smegmatis_MC2_155 HRIGLPGPGGRAELAEICGHIASLPLDRSRPLWEMWVIENVAGTDAHAGG
Mvan_3601|M.vanbaalenii_PYR-1 HRIGLPSPGGRVELAEICGHIASLPLDRTRPLWEMWVIENVAGTDAHAGG
TH_2477|M.thermoresistible__bu HRIGLPAPGGPAELAEICGHLAALPLDRSRPLWEMWVIENIDGTDPRSGG
MLBr_01244|M.leprae_Br4923 RRVRVPDPGTLREVFDLAEVIQQSPMDVSRPLWTATLVEGLA------AG
:*: :* ** *: :: : :* ::*** .:*.: .*
Rv1425|M.tuberculosis_H37Rv RIATLTKMHHAIVDGVSGAGLGEILLDITPEP-------RPPQQETVG-F
Mb1460|M.bovis_AF2122/97 RIATLTKMHHAIVDGVSGAGLGEILLDITPEP-------RPPQQETVG-F
MMAR_2231|M.marinum_M RIATLTKMHHAIVDGVSGAGLGEILLDVTPEP-------RPPQEETVG-F
MUL_1818|M.ulcerans_Agy99 RIATLTKMHHAIVDGVSGAGLGEILLDVTPEP-------RPPQEETVG-F
MAV_3352|M.avium_104 RFATLTKMHHAIVDGVSGAGLGEILLDATPEP-------RPPQQETVGSL
MAB_0507|M.abscessus_ATCC_1997 RVATLTKMHHAIVDGVSGAGLGEILLDIAPEP-------RPAPDDTVGSL
Mflv_0349|M.gilvum_PYR-GCK RVAVVTKMHHAVVDGVSGAGISEILLDTTPEP-------RPPAVDASRSL
MSMEG_4297|M.smegmatis_MC2_155 RLALMTKVHHASVDGVTGANLLSQLCTTEPDA-------PPP--DPVD--
Mvan_3601|M.vanbaalenii_PYR-1 RIAVMTKVHHAAVDGVTGANLMSKLCTTEPDA-------PPP--DPVA--
TH_2477|M.thermoresistible__bu PLVVLTKVHHAAVDGVTGANLLSQVCTTEADT-------PPP--EPVQ--
MLBr_01244|M.leprae_Br4923 RAAMLLQISHAITDGVGSVEMFAEMYDLERDPPSRPRSPQPIPQDLSRND
. : :: ** .*** .. : : :. * :
Rv1425|M.tuberculosis_H37Rv VGFQIPGLERRAIGALINVGIMTPFRIVR-LLEQTVRQQIAALGVAGKP-
Mb1460|M.bovis_AF2122/97 VGFQIPGLERRAIGALINVGIMTPFRIVR-LLEQTVRQQIAALGVAGKP-
MMAR_2231|M.marinum_M VGFQIPRLERRAVGALINVGIMTPFRIAR-LVEQTVRQQIAALGVSARP-
MUL_1818|M.ulcerans_Agy99 VGFQIPRLERRAVGALINVGIMTPFRIAR-LVEQTVRQQIAALGVSARP-
MAV_3352|M.avium_104 VGFQLPGLERRAVGALINVGVKTPFRIAR-LLEQTVRQQVATLGVRSRP-
MAB_0507|M.abscessus_ATCC_1997 VGLGLPSRERILLSALVNVGVKTPYRVAR-LVQQTVRQQLAVFGMERKS-
Mflv_0349|M.gilvum_PYR-GCK VGVKPPSRERQAVNGLINVWFKTPYRITR-LLEQTVRQQIAVRNIDNKP-
MSMEG_4297|M.smegmatis_MC2_155 -GPGGGTGLEIAVNGAVRFATR-PLRLVN-VVPSTLNTVVDTVRRARNGR
Mvan_3601|M.vanbaalenii_PYR-1 -GPGGGTDLEIAVSGAVRFATR-PLKLVN-VVPNTVSTVIDTVKRARNGL
TH_2477|M.thermoresistible__bu -GAGTASDLEIALSGAVRFATR-PLKLLN-VLPTTANSVLDTVRRARAGR
MLBr_01244|M.leprae_Br4923 LMLQGINHLPVALAGGVVGGLSGVASVAGRAILRPASTVSGVVGYVRSGI
: . : : : . .
Rv1425|M.tuberculosis_H37Rv --ARYFEAPKTRFNAPVSPHRRVTGTRVELARAKAVKDAFGVKLNDVVLA
Mb1460|M.bovis_AF2122/97 --ARYFEAPKTRFNAPVSPHRRVTGTRVELARAKAVKDAFGVKLNDVVLA
MMAR_2231|M.marinum_M --PRYFDAPKTRFNAHVSPHRRVSGCRIELARAKAVKDAFGVKLNDVVLA
MUL_1818|M.ulcerans_Agy99 --PRYFDAPKTRFNAHVSPHRRVSGCRIELARAKAVKDAFGVKLNDVVLA
MAV_3352|M.avium_104 --PRYFEAPKTRFNAPVSPHRRVTGCRVELARAKAIKDAYDVKLNDVVLA
MAB_0507|M.abscessus_ATCC_1997 --PGYFEAPHTRFNAPVSPHRRISGARLDLARVKALKDAFGVKVNDVVLA
Mflv_0349|M.gilvum_PYR-GCK --PRYFDAPKVRFNGPISPHRSVAGASVPLDRVKAVKNAFDVKLNDVVLA
MSMEG_4297|M.smegmatis_MC2_155 TMAAPFAAPRTAFNANITGHRNIAFAQLDLEDIKTVKNHFDVKVNDVVMA
Mvan_3601|M.vanbaalenii_PYR-1 TMAPPFAAPKTAFNANVTGHRNVAFAQLDLEDIKTVKNHFGVKVNDVVMA
TH_2477|M.thermoresistible__bu TMARPFAAPSTPFNANVTGRRNVAFTQLDLEDVKRIKDHFGVKVNDVVMA
MLBr_01244|M.leprae_Br4923 RVLSQAAEPSPLLRQRSLATR-TEAIEIQLSDLHKAAKAGDGSINDAYLA
* :. * : * : . . .:**. :*
Rv1425|M.tuberculosis_H37Rv LVAGAARQYLQKRDELPAKPLIAQIPVSTRSEETKADVGNQVSSMTASLA
Mb1460|M.bovis_AF2122/97 LVAGAARQYLQKRDELPAKPLIAQIPVSTRSEETKADVGNQVSSMTASLA
MMAR_2231|M.marinum_M TVAGAAREYLKKRDELPAKPLIAQIPVSTRTDQTKEDVGNQISSMTASLA
MUL_1818|M.ulcerans_Agy99 TVAGAAREYLKKRDELPAKPLIAQIPVSTRTDQTKEDVGNQISSMTASLA
MAV_3352|M.avium_104 LVAGAVRDYLQKRGELPAKPLIAQIPVSTRTDENKDDIGNKVSSMTVSLA
MAB_0507|M.abscessus_ATCC_1997 IVAGAVRDYLAKRDEFPDKPLIVQIPVSVRTEETDGVVGNQVSSMTVSLA
Mflv_0349|M.gilvum_PYR-GCK LVSGALRSYLKDRGELPAKSLVSQVPVSTR-AQADDTVGNQVNAMTVVLA
MSMEG_4297|M.smegmatis_MC2_155 LVSGVLRTFLSHRDELPDNSLVAMVPVSVH-DRSDRPGRNQVSGMFSPLQ
Mvan_3601|M.vanbaalenii_PYR-1 LVSGVLRTFLLERGELPESSLVAMVPVSVH-DKSDRPGRNQVSGMFSRLE
TH_2477|M.thermoresistible__bu LTSGALRSYLLERDQLPDSPLIAMVPVSVH-DKTDRPGRNHVSGMFSRLE
MLBr_01244|M.leprae_Br4923 GLVGALRRYHEALG-VSISTLPMAVPVNVR-TEADVVGSNRFVGVTLAAP
*. * : . .. ..* :**..: . . *:. .:
Rv1425|M.tuberculosis_H37Rv THIEDPAKRLAAIHESTLSAKEMAKAPSAHQIMGLTETTPPGLLQLAARA
Mb1460|M.bovis_AF2122/97 THIEDPAKRLAAIHESTLSAKEMAKALSAHQIMGLTETTPPGLLQLAARA
MMAR_2231|M.marinum_M THINDPAERLKAIHESTQNAKEMAKALSAHQIMGLTETTPPGLLHLAARA
MUL_1818|M.ulcerans_Agy99 THINDPAERLKAIHESTQNAKEMAKALSAHQIMGLTETTPPGLLHLAARA
MAV_3352|M.avium_104 THIEDPGERLRAIHDSTQSAKLMAKALSAHQIMGLTETTPPGLLHLAARA
MAB_0507|M.abscessus_ATCC_1997 TDIDDPAERIQAIYEGTQGAKEMARAMSAHQIMGLTDTTPPGLLQLAARA
Mflv_0349|M.gilvum_PYR-GCK TDVADPAERIKAIYSYTQGAKEMTKALTAHQIMGYTETTPPGLLALASRA
MSMEG_4297|M.smegmatis_MC2_155 THIADPAERLRAIAEANAVAKQHSSAIGATLLQDWTQFAAPAVFGTAMRV
Mvan_3601|M.vanbaalenii_PYR-1 TNIEDPATRLKAIAEANSVAKQHSSAIAATLLQDWTQFAAPAVFGAAMRV
TH_2477|M.thermoresistible__bu TTIEDPAERLRAIANANSVAKQHSSAIAASLLQDWTQFAAPAVFGVAMRV
MLBr_01244|M.leprae_Br4923 LGTNDPAARMQKIRSQMTQRRDEPAMNIIGSLAPLMTVLPASVLDFIVDS
**. *: * . : . : ...::
Rv1425|M.tuberculosis_H37Rv YTASGLSHNLAPINLVVSNVPGPPFPLYMAGARLDSLVPLGPPVMDVALN
Mb1460|M.bovis_AF2122/97 YTASGLSHNLAPINLVVSNVPGPPFPLYMAGARLDSLVPLGPPVMDVALN
MMAR_2231|M.marinum_M YTATGLSHNLAPINLVVSNVPGPQFPLYMAGARLDSLVPLGPPVMDVALN
MUL_1818|M.ulcerans_Agy99 YTATGLSHNLAPINLVVSNVPGPQFPLYMAGARLDSLVPLGPPVMDVALN
MAV_3352|M.avium_104 YTASGLSRNLAPINLVVSNVPGPPFPLYMAGAKLDSLVPLGPPVMDVALN
MAB_0507|M.abscessus_ATCC_1997 YTASGLSRNLAPINLVLSNVPGPSFPLYMAGARLESMIPLGPPVMDVALN
Mflv_0349|M.gilvum_PYR-GCK YAASGIGSNIAPMNVVISNVPGPTFPLYLGGARVEHLMPVGPLLFDVALN
MSMEG_4297|M.smegmatis_MC2_155 YAASRLSGAKPVHNLVVSNVPGPQVPLYFLGAEVKAMYPLGPIFHGSGLN
Mvan_3601|M.vanbaalenii_PYR-1 YASSRLSGARPVHNLVISNVPGPQGPLYMLGCEVKAMYPLGPIFHGSGLN
TH_2477|M.thermoresistible__bu YAASRLGEAKPVHNLVVSNVPGPQVPLYFLGAEVKAMYPLGPIFHGSGLN
MLBr_01244|M.leprae_Br4923 VASS---------DVNASNIPAYPGDTYFAGAKILRQYGIGP-RPGVAMM
::: :: **:*. *: *..: :** . .:
Rv1425|M.tuberculosis_H37Rv ITCFSYQDYLDFGLVTTPEVANDIDEMADAIEPALAELERAAE-------
Mb1460|M.bovis_AF2122/97 ITCFSYQDYLDFGLVTTPEVANDIDEMADAIEPALAELERAAE-------
MMAR_2231|M.marinum_M ITCFSYQEHLDFGFVTTPEVANDIDEMADLIEPALAELERAAGL------
MUL_1818|M.ulcerans_Agy99 ITCFSYQEHLDFGFVTTPEVANDIDEMADLIEPALAELERAAGL------
MAV_3352|M.avium_104 ITCFSYTDYLDFGFVTTPEVANDIDDMADRIEPALTDLEKAAAGETG---
MAB_0507|M.abscessus_ATCC_1997 ITCFSYLEHMDFGFVTTPEVAADIDEMADGLEAALVELEHAVGI------
Mflv_0349|M.gilvum_PYR-GCK VTCFSYCGAVDFGFITTPEIAADIVDLADQIEPALHDLEVAAGLVSDPTR
MSMEG_4297|M.smegmatis_MC2_155 ITVMSLTGKLDVGIISCPELLPDLWDMADDFAVALDELLDATKRA-----
Mvan_3601|M.vanbaalenii_PYR-1 MTVMSLSGKLDVGIVSCPELLPDLWDMADTFGVALQELLDATR-------
TH_2477|M.thermoresistible__bu ITVMSLTGRLNVGMVSCPELMPDLWELAEGFERALRELLDTVG-------
MLBr_01244|M.leprae_Br4923 AVLMSRGGFCTVTVRYDRASVKSEALFARCLLEGFDEVLALAGDPTPHAV
. :* . . . :* : .: :: .
Rv1425|M.tuberculosis_H37Rv -------------------
Mb1460|M.bovis_AF2122/97 -------------------
MMAR_2231|M.marinum_M -------------------
MUL_1818|M.ulcerans_Agy99 -------------------
MAV_3352|M.avium_104 -------------------
MAB_0507|M.abscessus_ATCC_1997 -------------------
Mflv_0349|M.gilvum_PYR-GCK PKPRKRGRR----------
MSMEG_4297|M.smegmatis_MC2_155 -------------------
Mvan_3601|M.vanbaalenii_PYR-1 -------------------
TH_2477|M.thermoresistible__bu -------------------
MLBr_01244|M.leprae_Br4923 PASFAARSSGSPAGWLSSS