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VERMTAFDAGFLDAEDADRHVSLAVGAVSVVDGPMPDFDEIVAAIGEKIVTIPRLRQVVRRQPLDLSAPE WVEDPTLDLAHHIRRAALPHPGDDDALFRFTAEAMEPRLDRERPLWQAWIIEGLADDRWAILMKVHHCIA DGIAAMHMLAGLSDDGEGETYAGAIRAAHEAGASRPALPSPTLNPVRWARAGWNATTAVAATAAMTVEGA IGILSGLVRNAESSLNGPVTTMRRYSAVQVPLATVASVCQAFDVTLNDVALAAITDSFRSALKRRGEEPR RDSLRTLVPVSVRSDDARDRLDNRVSVMLPHLPVDEPDPVEQLRTVHRRLNRAKSSGQRQAGTAAVAAVK LIPFALATRAIRAVTSLPQHGVVTLATNVPGPQHRLQVMGREVVRMFPVPPMALRLRTAVAILSYGDDLV FGITTDFDAFPDVDELAAGIGAAVDTLAAAARPL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4977 | - | - | 100% (454) | hypothetical protein Mflv_4977 |
| M. gilvum PYR-GCK | Mflv_2541 | - | e-140 | 56.79% (449) | hypothetical protein Mflv_2541 |
| M. gilvum PYR-GCK | Mflv_0349 | - | 1e-49 | 31.58% (475) | hypothetical protein Mflv_0349 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3154c | - | 1e-132 | 51.11% (452) | hypothetical protein Mb3154c |
| M. tuberculosis H37Rv | Rv3130c | tgs1 | 1e-132 | 51.11% (452) | triacylglycerol synthase |
| M. leprae Br4923 | MLBr_01244 | - | 4e-26 | 25.06% (403) | hypothetical protein MLBr_01244 |
| M. abscessus ATCC 19977 | MAB_3551c | - | 2e-50 | 31.21% (487) | hypothetical protein MAB_3551c |
| M. marinum M | MMAR_1519 | - | 1e-136 | 52.43% (452) | hypothetical protein MMAR_1519 |
| M. avium 104 | MAV_4336 | - | 3e-88 | 43.21% (442) | acyltransferase, ws/dgat/mgat subfamily protein |
| M. smegmatis MC2 155 | MSMEG_3948 | - | 1e-141 | 55.80% (448) | acyltransferase, ws/dgat/mgat subfamily protein |
| M. thermoresistible (build 8) | TH_2686 | - | 1e-49 | 28.99% (483) | PUTATIVE Diacylglycerol O-acyltransferase |
| M. ulcerans Agy99 | MUL_2420 | - | 1e-134 | 51.66% (453) | hypothetical protein MUL_2420 |
| M. vanbaalenii PYR-1 | Mvan_4104 | - | 1e-146 | 58.94% (453) | hypothetical protein Mvan_4104 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3154c|M.bovis_AF2122/97 --------MNHLTTLDAG-----FLKAEDVDRHVSLAIGALAVIEGPAP-
Rv3130c|M.tuberculosis_H37Rv --------MNHLTTLDAG-----FLKAEDVDRHVSLAIGALAVIEGPAP-
MMAR_1519|M.marinum_M --------MNHLTTLDSG-----FLKAEDVDPRVSLAIGGLAVIEGPVP-
MUL_2420|M.ulcerans_Agy99 --------MNHLTTLDSG-----FLKAEDVDPRVSLAIGGLAVIEGPVP-
Mflv_4977|M.gilvum_PYR-GCK --------MERMTAFDAG-----FLDAEDADRHVSLAVGAVSVVDGPMP-
Mvan_4104|M.vanbaalenii_PYR-1 --------MEHLSTLDAS-----FLQAEDSDPHVSLAVGAVSIIEGPAP-
MSMEG_3948|M.smegmatis_MC2_155 -----------MSALDVA-----FLEAEDADRNVSLVIGVLAILEGSPP-
MAV_4336|M.avium_104 ----------MAQTLDTA-----FLKAHDPDQHASLAIGAVAIVDGTVP-
MAB_3551c|M.abscessus_ATCC_199 MGKAARIVVSRLSALDAS-----FYSSEDS--ATPMHVGSLAIIRRPRGG
TH_2686|M.thermoresistible__bu -------MVTRLSASDAD-----FFHLEDT--STPMYVGSLAILRRPRGG
MLBr_01244|M.leprae_Br4923 ----MADSVEGIGPFDELGALDYLLHRGEANPRTRAGIMAVELLDTTPD-
. * : : . : : :: .
Mb3154c|M.bovis_AF2122/97 -DQEAFLSSLAQRLRPCTRFGQRLRLRPFDLGAPKWVDDPDFDLGRHVWR
Rv3130c|M.tuberculosis_H37Rv -DQEAFLSSLAQRLRPCTRFGQRLRLRPFDLGAPKWVDDPDFDLGRHVWR
MMAR_1519|M.marinum_M -EQHDLVSVFSERIRACPRFAQRLRRYPFDLGAPQWVDDPDFDIARHVRR
MUL_2420|M.ulcerans_Agy99 -EQHDLVSVFSERIRACPRFAQRLRRYPFDLGAPQWVDDPDFDIARHVRR
Mflv_4977|M.gilvum_PYR-GCK -DFDEIVAAIGEKIVTIPRLRQVVRRQPLDLSAPEWVEDPTLDLAHHIRR
Mvan_4104|M.vanbaalenii_PYR-1 -DYDDLVAAFAERAQGIPRCTQIVHTRPFDLAAPEWVDDPHFDIAHHLHR
MSMEG_3948|M.smegmatis_MC2_155 -TDHVLLGSVYNRLMSIPRFTQIVERQPLDLAAPQWVEAHDFSVAHHVRR
MAV_4336|M.avium_104 -DPAQLEHLVAERILPIARCTQLLRAHPLNR---EWVDCPDFDLAWHLRR
MAB_3551c|M.abscessus_ATCC_199 FTYEELLALVESRLPQVPRYRQKVKEIGFGLARPVWLDDVDFDITYHIRR
TH_2686|M.thermoresistible__bu LSYETLLATVEQRLPQIPRYRQKVRKAPIGLARPVWVDDPDFDITYHVRR
MLBr_01244|M.leprae_Br4923 --WNRFRSRIEDVSQRVLRLRQKVVVPTLPTAAPRWVVDPDFELDFHVRR
: . . * * : : *: :.: *: *
Mb3154c|M.bovis_AF2122/97 IALPRPGNEDQLFELIADLMARRLDRGRPLWEVWVIEGLADSKWAILTKL
Rv3130c|M.tuberculosis_H37Rv IALPRPGNEDQLFELIADLMARRLDRGRPLWEVWVIEGLADSKWAILTKL
MMAR_1519|M.marinum_M VALPHPGDDDALHRLVADVMARRLDRDRPLWELWVIEGLAGERWAMLTKV
MUL_2420|M.ulcerans_Agy99 VALPHPGDDDALYRLVADVMGRRLDRDRPLWELWVIEGLAGERWAMLTKV
Mflv_4977|M.gilvum_PYR-GCK AALPHPGDDDALFRFTAEAMEPRLDRERPLWQAWIIEGLADDRWAILMKV
Mvan_4104|M.vanbaalenii_PYR-1 IALPAPGDDAEMFTTIAGIMERRLDRDRPLWECWIIEGLADGRWATLMKI
MSMEG_3948|M.smegmatis_MC2_155 TAVPQPGDDTALFGVVADIMERRLDRSRPLWECWIIEGLPSDRWAILMKI
MAV_4336|M.avium_104 VAIAGTGDEAELSRVIGQALRRPLDPGRPPWECWVIEGLRGNRWAMLMKT
MAB_3551c|M.abscessus_ATCC_199 SALPSPGSDGQLQDLVARLTSRPLDRSRPLWEMYLVEGLSKNRLAIYTKT
TH_2686|M.thermoresistible__bu SALPSPGSDAQLHELIARLASRPLDKTRPLWEMYLIEGLAKNRLALYTKS
MLBr_01244|M.leprae_Br4923 VRVPDPGTLREVFDLAEVIQQSPMDVSRPLWTATLVEGLAAGRAAMLLQI
:. .* : :* ** * ::*** : * :
Mb3154c|M.bovis_AF2122/97 HHCMADGIAATHLLAGLSDESMSDSFASNIHTTMQSQSASVRRGGFRVNP
Rv3130c|M.tuberculosis_H37Rv HHCMADGIAATHLLAGLSDESMSDSFASNIHTTMQSQSASVRRGGFRVNP
MMAR_1519|M.marinum_M HHCMADGIAVTHILTGLCDR-DGGGAADGSARCRAAQRPKTAAAHPRSGL
MUL_2420|M.ulcerans_Agy99 HHCMADGIAATHILTGLCDR-DGGGAADGSARCRAAQRPKTAAARPRSGL
Mflv_4977|M.gilvum_PYR-GCK HHCIADGIAAMHMLAGLSDDGEGETYAGAIRAAHEAGASRPALPSPTLNP
Mvan_4104|M.vanbaalenii_PYR-1 HHCIADGIATAQMLAKLSDDGAGETFAADIRAAQESGPSILGLLRPRLNP
MSMEG_3948|M.smegmatis_MC2_155 HHCIADGIAAAQLLSYLSDEGTVDSFSSDIDGAKPTAPQKNRRFELTLNP
MAV_4336|M.avium_104 HHGLLDGNPAARLITRLCDDADADMFANNAAAQPVSSP------------
MAB_3551c|M.abscessus_ATCC_199 HQALVDGNSALSLGQVIFDRTARTPDFGEDIWVPEHEPSTSELVAGAVSE
TH_2686|M.thermoresistible__bu HQALVNGMTAPEIGHVIADRTQKPPQFGEDIWMPGREPGTAQLLIGAIGD
MLBr_01244|M.leprae_Br4923 SHAITDGVGSVEMFAEMYDLERDPPSRPRSPQPIPQDLSRNDLMLQGINH
: : :* : : *
Mb3154c|M.bovis_AF2122/97 S------------EALTASTAVMA-------GIVRAAKGASEIAAGVLS-
Rv3130c|M.tuberculosis_H37Rv S------------EALTASTAVMA-------GIVRAAKGASEIAAGVLS-
MMAR_1519|M.marinum_M S------------GLWNAPAAIAS-------GVVRLAQGAEELVTGLLT-
MUL_2420|M.ulcerans_Agy99 S------------GLWNAPAAIAS-------GVVRLAQGSGELVTGLLT-
Mflv_4977|M.gilvum_PYR-GCK VRWAR--------AGWNATTAVAA-------TAAMTVEGAIGILSGLVR-
Mvan_4104|M.vanbaalenii_PYR-1 LDWMN--------GAWRATLAAAG-------AAEHAVVGAAELTARVLTP
MSMEG_3948|M.smegmatis_MC2_155 VRLIR--------SAVDATASVGS-------EVIRVAEGALQIASGLLD-
MAV_4336|M.avium_104 -------------TGWLDALSRVS-------SLTGGLLGALRLAG-----
MAB_3551c|M.abscessus_ATCC_199 WLARPGARLEAVRNTVADVASLTG-------EIGELGERMVKVVRTAARG
TH_2686|M.thermoresistible__bu WLTRPGAQMIAVRDNVLGMATNAG-------ELVDAGRRALSVARTVARG
MLBr_01244|M.leprae_Br4923 LPVALAG---GVVGGLSGVASVAGRAILRPASTVSGVVGYVRSGIRVLSQ
: .
Mb3154c|M.bovis_AF2122/97 -PAASSLNGPISDLRRYSAAKVPLADVEQVCRKFDVTINDVALAAITESY
Rv3130c|M.tuberculosis_H37Rv -PAASSLNGPISDLRRYSAAKVPLADVEQVCRKFDVTINDVALAAITESY
MMAR_1519|M.marinum_M -PAASALTGPLSDLRRFSGARVPMADLELVCETFDVTINDVALAAITESY
MUL_2420|M.ulcerans_Agy99 -PVASALTGPLSDLRRFSGARVPMADLELVCETFDVTINDVALAAITESY
Mflv_4977|M.gilvum_PYR-GCK -NAESSLNGPVTTMRRYSAVQVPLATVASVCQAFDVTLNDVALAAITDSF
Mvan_4104|M.vanbaalenii_PYR-1 -GQESSLNGPVTGMRRYSAAVVDLAVMKQVSRNFDVTLNDVALAAITNGY
MSMEG_3948|M.smegmatis_MC2_155 -SHPLPLRGPVTDLRRYASTQVSLADVGRICHAYDVTINDVALAAITDSF
MAV_4336|M.avium_104 ------RAEAVAPVRRYATVRVPIADVDRVCRKFGVSANDVALAAVTEGF
MAB_3551c|M.abscessus_ATCC_199 AAPRGPLNQRVSRSRRFGVVSTKLADYRRVRAKYDCDVNDVVLATIAGAL
TH_2686|M.thermoresistible__bu TAPSSPLNTRVSRNRRFTVARHRLDDYRKVRARYDCDVNDVVLAVIAGAL
MLBr_01244|M.leprae_Br4923 AAEPSPLLRQRSLATRTEAIEIQLSDLHKAAKAGDGSINDAYLAGLVGAL
: * : . **. ** :. .
Mb3154c|M.bovis_AF2122/97 RNVLIQRGE-RPRFDSLRTLVPVSTRSNSALSKTD-----NRVSLMLPNL
Rv3130c|M.tuberculosis_H37Rv RNVLIQRGE-RPRFDSLRTLVPVSTRSNSALSKTD-----NRVSLMLPNL
MMAR_1519|M.marinum_M RNVLLARGQ-QPQQGSLRTLVPVSVRADNAFDKTD-----NRVSAMLPNL
MUL_2420|M.ulcerans_Agy99 RNVLLARGQ-QPQQGSLRTLVPVSVRADNAFDKTD-----NRVSAMLPNL
Mflv_4977|M.gilvum_PYR-GCK RSALKRRGE-EPRRDSLRTLVPVSVRSDDARDRLD-----NRVSVMLPHL
Mvan_4104|M.vanbaalenii_PYR-1 RHMLLDRGE-SPGPHALRTLVPVSMRSAGDFDVTD-----NRVSAMLPLL
MSMEG_3948|M.smegmatis_MC2_155 RAAMIRRGE-RPGARSLRTLVPVSVRSNDAAAQVD-----NRVSLMLPCL
MAV_4336|M.avium_104 RTVLLDRGE-QPRADSLRTLVPLPVR-----------------SAVLSHL
MAB_3551c|M.abscessus_ATCC_199 RNWLMSRGEPVTTASTIRAMVPMSVYRDGDLDVGGEGAATTEVSPFLVDL
TH_2686|M.thermoresistible__bu RNWLLSRGEQVSSTATVRAMAPLSVQSDAELDSTAPGQAVSDVVPFLIDL
MLBr_01244|M.leprae_Br4923 RRYHEALGV---SISTLPMAVPVNVRTEADVVGSN------RFVGVTLAA
* * :: .*: .
Mb3154c|M.bovis_AF2122/97 PVDQENPLQRLRIVHSRLTRAKAGGQRQFGNTLMAIANRLPFPMTAWAVG
Rv3130c|M.tuberculosis_H37Rv PVDQENPLQRLRIVHSRLTRAKAGGQRQFGNTLMAIANRLPFPMTAWAVG
MMAR_1519|M.marinum_M PVDEEDPVQRLRKVHARLGQTKASGQPQAGNLFLSLADRIPFALTAWTVG
MUL_2420|M.ulcerans_Agy99 PVDEEDPVQRLRKVHARLGQTKASGQPRAGNLFLSLADRIPFALTAWTVG
Mflv_4977|M.gilvum_PYR-GCK PVDEPDPVEQLRTVHRRLNRAKSSGQRQAGTAAVAAVKLIPFALATRAIR
Mvan_4104|M.vanbaalenii_PYR-1 PVDEPDPVRQLEIVHRRLSRAKGSGQREGGDAVLAAAGNIPFALSAWTIR
MSMEG_3948|M.smegmatis_MC2_155 PVDIHDPVEQLLTVHRRMENAKRTGQRQAGSVFVSAVNSLPFGITTLLVR
MAV_4336|M.avium_104 PVEHDDPVRRLQTVHARCN--PAAGTQPAG-IVESAIGLVPNMVRGNLIQ
MAB_3551c|M.abscessus_ATCC_199 PVGEGNTVVRLSQIAHATESHSAAFSLVDVPNMAALSGFVPPTLHALAAR
TH_2686|M.thermoresistible__bu PVGERNPVVRLSQISHATETHPTASSLVDARTIVTLTGFAPATLHAMGVR
MLBr_01244|M.leprae_Br4923 PLGTNDPAARMQKIRSQMTQRRDEPAMNIIGSLAPLMTVLPASVLDFIVD
*: :. :: : . * :
Mb3154c|M.bovis_AF2122/97 LLMRLPQRGVVTVATNVPGPRRPLQIMGRRVLDLYPVSPIAMQLRTSVAM
Rv3130c|M.tuberculosis_H37Rv LLMRLPQRGVVTVATNVPGPRRPLQIMGRRVLDLYPVSPIAMQLRTSVAM
MMAR_1519|M.marinum_M VLMRLPQRGVATVATNVPGPRQPLQIMGRPVAAVFPVPPLAMHLRTGVAM
MUL_2420|M.ulcerans_Agy99 VLMRLPQRGVATVATNVPGPRQPLQIMGRPVAAVFPVPPLAMHLRTGVAM
Mflv_4977|M.gilvum_PYR-GCK AVTSLPQHGVVTLATNVPGPQHRLQVMGREVVRMFPVPPMALRLRTAVAI
Mvan_4104|M.vanbaalenii_PYR-1 LLTRLPQRSVTALATNVPGPRGRQRVLGRKVVEILPIPPIALHLRTGIAM
MSMEG_3948|M.smegmatis_MC2_155 AAVRMPQQSVVTLATNVPGPRQHLKLLGHRVVRVVPIPPIALGLRTGVAI
MAV_4336|M.avium_104 LLSRLPQRAVVTLATNVPGPRRRLRVMGQTLERLLPVPPTATQLHTGVAV
MAB_3551c|M.abscessus_ATCC_199 VASTLPNRLFNLLVTNVPGPQAPMYLGGARLAEIYPVPPLLRNQVLSIGL
TH_2686|M.thermoresistible__bu VATNFSARQFNLLITNVPGAQKQMYIAGTKMLESYSVPPLLRNQVLAVAV
MLBr_01244|M.leprae_Br4923 SVASSDVN-----ASNIPAYPGDTYFAGAKILRQYGIGPRP-GVAMMAVL
. :*:*. . * : : * :
Mb3154c|M.bovis_AF2122/97 LSYADDLYFGILADYDVVADAGQLARGIEDAVARLVAISK--------RR
Rv3130c|M.tuberculosis_H37Rv LSYADDLYFGILADYDVVADAGQLARGIEDAVARLVAISK--------RR
MMAR_1519|M.marinum_M LSYSDDLYFGILTDYNAVADVDQLARGIEAAVARLVAISK--------RR
MUL_2420|M.ulcerans_Agy99 LSYSDDLYFGILTDYNPVADVDQLARGTEAAVARLVAISK--------RR
Mflv_4977|M.gilvum_PYR-GCK LSYGDDLVFGITTDFDAFPDVDELAAGIGAAVDTLAAAAR--------PL
Mvan_4104|M.vanbaalenii_PYR-1 LSYAGRFSFGITADYDSAPDVDALARGIGEGVRCLAELGR--------AE
MSMEG_3948|M.smegmatis_MC2_155 LSYADDLVFGITADFDAIPDVEVLADDIQRAVARLARTAE--------LP
MAV_4336|M.avium_104 LSYGDELVFGITAGPGDGFDVTRLAAAVELGMARLAALGDDSVLLFADRR
MAB_3551c|M.abscessus_ATCC_199 TSYNGTVYYGINADREAMPDADMLPLLITEALDELLEAAQ----------
TH_2686|M.thermoresistible__bu TSYHGMLYYGVNADRDAMSDVEVLPSLLSESLDELLEAAQ----------
MLBr_01244|M.leprae_Br4923 MSRGGFCTVTVRYDRASVKSEALFARCLLEGFDEVLALAGDPTPHAVPAS
* . : . . :. .. : .
Mb3154c|M.bovis_AF2122/97 KVTRRRGALSLVV------------
Rv3130c|M.tuberculosis_H37Rv KVTRRRGALSLVV------------
MMAR_1519|M.marinum_M KARRARGPLSLVV------------
MUL_2420|M.ulcerans_Agy99 KARRGRGPLSLVV------------
Mflv_4977|M.gilvum_PYR-GCK -------------------------
Mvan_4104|M.vanbaalenii_PYR-1 RRTPPDGAGRPIADAP---------
MSMEG_3948|M.smegmatis_MC2_155 TRRAPDGTLTVVTTPR---------
MAV_4336|M.avium_104 RRRAARSPLGRVPPAHPSAPGHARH
MAB_3551c|M.abscessus_ATCC_199 -------------------------
TH_2686|M.thermoresistible__bu -------------------------
MLBr_01244|M.leprae_Br4923 FAARSSGSPAGWLSSS---------