For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MQRLSGVDAAFWHAETAGWHMHIGGLSIYDPTDAPDYSFERVRALIVERLPSMPQLRWRVTDVPLGLDRP WFVEDEELDPDFHIRRIGVPAPGGRKELEELAGRLMSYKLDRSRPLWELWVIEGVEGGRVATLTKMHHAI VDGVSGAGLGEILLDIAPEPRPAPDDTVGSLVGLGLPSRERILLSALVNVGVKTPYRVARLVQQTVRQQL AVFGMERKSPGYFEAPHTRFNAPVSPHRRISGARLDLARVKALKDAFGVKVNDVVLAIVAGAVRDYLAKR DEFPDKPLIVQIPVSVRTEETDGVVGNQVSSMTVSLATDIDDPAERIQAIYEGTQGAKEMARAMSAHQIM GLTDTTPPGLLQLAARAYTASGLSRNLAPINLVLSNVPGPSFPLYMAGARLESMIPLGPPVMDVALNITC FSYLEHMDFGFVTTPEVAADIDEMADGLEAALVELEHAVGI
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. abscessus ATCC 19977 | MAB_0507 | - | - | 100% (461) | hypothetical protein MAB_0507 |
M. abscessus ATCC 19977 | MAB_1917 | - | 3e-85 | 39.91% (466) | hypothetical protein MAB_1917 |
M. abscessus ATCC 19977 | MAB_3964 | - | 4e-57 | 33.97% (468) | hypothetical protein MAB_3964 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1460 | - | 0.0 | 77.07% (458) | hypothetical protein Mb1460 |
M. gilvum PYR-GCK | Mflv_0349 | - | 1e-180 | 65.14% (459) | hypothetical protein Mflv_0349 |
M. tuberculosis H37Rv | Rv1425 | - | 0.0 | 77.07% (458) | hypothetical protein Rv1425 |
M. leprae Br4923 | MLBr_01244 | - | 2e-23 | 26.10% (387) | hypothetical protein MLBr_01244 |
M. marinum M | MMAR_2231 | - | 0.0 | 76.57% (461) | hypothetical protein MMAR_2231 |
M. avium 104 | MAV_3352 | - | 0.0 | 74.62% (461) | acyltransferase, ws/dgat/mgat subfamily protein |
M. smegmatis MC2 155 | MSMEG_4297 | - | 8e-92 | 42.58% (465) | acyltransferase, ws/dgat/mgat subfamily protein |
M. thermoresistible (build 8) | TH_2477 | - | 9e-92 | 42.32% (475) | PUTATIVE acyltransferase, ws/dgat/mgat subfamily protein |
M. ulcerans Agy99 | MUL_1818 | - | 0.0 | 76.57% (461) | hypothetical protein MUL_1818 |
M. vanbaalenii PYR-1 | Mvan_3601 | - | 3e-90 | 41.54% (467) | hypothetical protein Mvan_3601 |
CLUSTAL 2.0.9 multiple sequence alignment Mb1460|M.bovis_AF2122/97 ---------------MKRLSSVDAAFWSAETAGWHMHVGALAICDPSDAP Rv1425|M.tuberculosis_H37Rv ---------------MKRLSSVDAAFWSAETAGWHMHVGALAICDPSDAP MMAR_2231|M.marinum_M ---------------MRRLSSVDAAFWSAETAGWHMHVGALAICDPTDAP MUL_1818|M.ulcerans_Agy99 ---------------MRRLSSVDAAFWSAETAGWHMHVGALAICDPTDAP MAV_3352|M.avium_104 --------------MMKRLSSVDAAFWSAETAGWHMHVGALAICDPKGSA MAB_0507|M.abscessus_ATCC_1997 ---------------MQRLSGVDAAFWHAETAGWHMHIGGLSIYDPTDAP Mflv_0349|M.gilvum_PYR-GCK ----------------MRLSSVDAAFWFAENLKWHMHIGAIALCDPSDVP MSMEG_4297|M.smegmatis_MC2_155 ---------------MQRLSGLDASFLYLETAAQPMHVCSVLELDTSTMP Mvan_3601|M.vanbaalenii_PYR-1 MDLLTPAPPRHTIGGMQRLSGLDASFLYLESAAQPLHVCSILELDTSTMP TH_2477|M.thermoresistible__bu ------VPPPYDRG-MQRLSGLDASFLYLETPDQPLHVCSILELDTSTIP MLBr_01244|M.leprae_Br4923 -----MADSVEGIGPFDELGALDYLLHRGEANPR-TRAGIMAVELLDTTP .*..:* : * : : . Mb1460|M.bovis_AF2122/97 -EYSFQRLRELIIERLPEIPQLRWRVTGAPLGLDRPWFVEDEELDIDFHI Rv1425|M.tuberculosis_H37Rv -EYSFQRLRELIIERLPEIPQLRWRVTGAPLGLDRPWFVEDEELDIDFHI MMAR_2231|M.marinum_M -DYSFQRLRELLIERLPEIPQLRWRVTGAPLGLDRPWFVEDQDLDVDFHV MUL_1818|M.ulcerans_Agy99 -DYSFQRLRELLIERLPEIPQLRWRVTGAPLGLDRPWFVEDQDLDVDFHV MAV_3352|M.avium_104 -EYTFERLRQLLIERLPEVPQLRWRVTGAPLGLDRPWFVEDEELDVDFHL MAB_0507|M.abscessus_ATCC_1997 -DYSFERVRALIVERLPSMPQLRWRVTDVPLGLDRPWFVEDEELDPDFHI Mflv_0349|M.gilvum_PYR-GCK -DFGFEQVRDLIISRLPELPQLRWRVVGAPLGLDRPYFVEDEDIDVDFHI MSMEG_4297|M.smegmatis_MC2_155 GGYTFDRLRDALSLRIKAMPEFREKLADSRFNLDHPVWVEDNDFDVDRHL Mvan_3601|M.vanbaalenii_PYR-1 GGYTFDRLRDGLALRIKAMPEFREKIADSRFNLDHPVWVEDNDFDVDRHL TH_2477|M.thermoresistible__bu GGYDFHQLREALLLRIKAMPEFREKLADNRFNLDHPVWVEDADFDVDRHL MLBr_01244|M.leprae_Br4923 ---DWNRFRSRIEDVSQRVLRLRQKVVVPTLPTAAPRWVVDPDFELDFHV :.:.* : : .:* ::. : * :* * ::: * *: Mb1460|M.bovis_AF2122/97 RRIGVPAPGGRRELEELVGRLMSYKLDRSRPLWELWVIEGVE------GG Rv1425|M.tuberculosis_H37Rv RRIGVPAPGGRRELEELVGRLMSYKLDRSRPLWELWVIEGVE------GG MMAR_2231|M.marinum_M RRIGVPAPGGRRELEELVGRLMSYKLDRSRPLWELWVIEGVE------GG MUL_1818|M.ulcerans_Agy99 RRIGVPAPGGRRELEELVGRLMSYKLDRSRPLWELWVIEGVE------GG MAV_3352|M.avium_104 RRIGVPAPGGRRELEELVGRLMSYKLDRSRPLWEMWVIEGLDGN---AGG MAB_0507|M.abscessus_ATCC_1997 RRIGVPAPGGRKELEELAGRLMSYKLDRSRPLWELWVIEGVE------GG Mflv_0349|M.gilvum_PYR-GCK RRIAVPSPGGRKELDDLVGRLMSYKLDRSKPLWELWFIEGLE------GG MSMEG_4297|M.smegmatis_MC2_155 HRIGLPGPGGRAELAEICGHIASLPLDRSRPLWEMWVIENVAGTDAHAGG Mvan_3601|M.vanbaalenii_PYR-1 HRIGLPSPGGRVELAEICGHIASLPLDRTRPLWEMWVIENVAGTDAHAGG TH_2477|M.thermoresistible__bu HRIGLPAPGGPAELAEICGHLAALPLDRSRPLWEMWVIENIDGTDPRSGG MLBr_01244|M.leprae_Br4923 RRVRVPDPGTLREVFDLAEVIQQSPMDVSRPLWTATLVEGLA------AG :*: :* ** *: :: : :* ::*** .:*.: .* Mb1460|M.bovis_AF2122/97 RIATLTKMHHAIVDGVSGAGLGEILLDITPEP-------RPPQQETVG-F Rv1425|M.tuberculosis_H37Rv RIATLTKMHHAIVDGVSGAGLGEILLDITPEP-------RPPQQETVG-F MMAR_2231|M.marinum_M RIATLTKMHHAIVDGVSGAGLGEILLDVTPEP-------RPPQEETVG-F MUL_1818|M.ulcerans_Agy99 RIATLTKMHHAIVDGVSGAGLGEILLDVTPEP-------RPPQEETVG-F MAV_3352|M.avium_104 RFATLTKMHHAIVDGVSGAGLGEILLDATPEP-------RPPQQETVGSL MAB_0507|M.abscessus_ATCC_1997 RVATLTKMHHAIVDGVSGAGLGEILLDIAPEP-------RPAPDDTVGSL Mflv_0349|M.gilvum_PYR-GCK RVAVVTKMHHAVVDGVSGAGISEILLDTTPEP-------RPPAVDASRSL MSMEG_4297|M.smegmatis_MC2_155 RLALMTKVHHASVDGVTGANLLSQLCTTEPDA-------PPP--DPVD-- Mvan_3601|M.vanbaalenii_PYR-1 RIAVMTKVHHAAVDGVTGANLMSKLCTTEPDA-------PPP--DPVA-- TH_2477|M.thermoresistible__bu PLVVLTKVHHAAVDGVTGANLLSQVCTTEADT-------PPP--EPVQ-- MLBr_01244|M.leprae_Br4923 RAAMLLQISHAITDGVGSVEMFAEMYDLERDPPSRPRSPQPIPQDLSRND . : :: ** .*** .. : : :. * : Mb1460|M.bovis_AF2122/97 VGFQIPGLERRAIGALINVGIMTPFRIVR-LLEQTVRQQIAALGVAGKP- Rv1425|M.tuberculosis_H37Rv VGFQIPGLERRAIGALINVGIMTPFRIVR-LLEQTVRQQIAALGVAGKP- MMAR_2231|M.marinum_M VGFQIPRLERRAVGALINVGIMTPFRIAR-LVEQTVRQQIAALGVSARP- MUL_1818|M.ulcerans_Agy99 VGFQIPRLERRAVGALINVGIMTPFRIAR-LVEQTVRQQIAALGVSARP- MAV_3352|M.avium_104 VGFQLPGLERRAVGALINVGVKTPFRIAR-LLEQTVRQQVATLGVRSRP- MAB_0507|M.abscessus_ATCC_1997 VGLGLPSRERILLSALVNVGVKTPYRVAR-LVQQTVRQQLAVFGMERKS- Mflv_0349|M.gilvum_PYR-GCK VGVKPPSRERQAVNGLINVWFKTPYRITR-LLEQTVRQQIAVRNIDNKP- MSMEG_4297|M.smegmatis_MC2_155 -GPGGGTGLEIAVNGAVRFATR-PLRLVN-VVPSTLNTVVDTVRRARNGR Mvan_3601|M.vanbaalenii_PYR-1 -GPGGGTDLEIAVSGAVRFATR-PLKLVN-VVPNTVSTVIDTVKRARNGL TH_2477|M.thermoresistible__bu -GAGTASDLEIALSGAVRFATR-PLKLLN-VLPTTANSVLDTVRRARAGR MLBr_01244|M.leprae_Br4923 LMLQGINHLPVALAGGVVGGLSGVASVAGRAILRPASTVSGVVGYVRSGI : . : : : . . Mb1460|M.bovis_AF2122/97 --ARYFEAPKTRFNAPVSPHRRVTGTRVELARAKAVKDAFGVKLNDVVLA Rv1425|M.tuberculosis_H37Rv --ARYFEAPKTRFNAPVSPHRRVTGTRVELARAKAVKDAFGVKLNDVVLA MMAR_2231|M.marinum_M --PRYFDAPKTRFNAHVSPHRRVSGCRIELARAKAVKDAFGVKLNDVVLA MUL_1818|M.ulcerans_Agy99 --PRYFDAPKTRFNAHVSPHRRVSGCRIELARAKAVKDAFGVKLNDVVLA MAV_3352|M.avium_104 --PRYFEAPKTRFNAPVSPHRRVTGCRVELARAKAIKDAYDVKLNDVVLA MAB_0507|M.abscessus_ATCC_1997 --PGYFEAPHTRFNAPVSPHRRISGARLDLARVKALKDAFGVKVNDVVLA Mflv_0349|M.gilvum_PYR-GCK --PRYFDAPKVRFNGPISPHRSVAGASVPLDRVKAVKNAFDVKLNDVVLA MSMEG_4297|M.smegmatis_MC2_155 TMAAPFAAPRTAFNANITGHRNIAFAQLDLEDIKTVKNHFDVKVNDVVMA Mvan_3601|M.vanbaalenii_PYR-1 TMAPPFAAPKTAFNANVTGHRNVAFAQLDLEDIKTVKNHFGVKVNDVVMA TH_2477|M.thermoresistible__bu TMARPFAAPSTPFNANVTGRRNVAFTQLDLEDVKRIKDHFGVKVNDVVMA MLBr_01244|M.leprae_Br4923 RVLSQAAEPSPLLRQRSLATR-TEAIEIQLSDLHKAAKAGDGSINDAYLA * :. * : * : . . .:**. :* Mb1460|M.bovis_AF2122/97 LVAGAARQYLQKRDELPAKPLIAQIPVSTRSEETKADVGNQVSSMTASLA Rv1425|M.tuberculosis_H37Rv LVAGAARQYLQKRDELPAKPLIAQIPVSTRSEETKADVGNQVSSMTASLA MMAR_2231|M.marinum_M TVAGAAREYLKKRDELPAKPLIAQIPVSTRTDQTKEDVGNQISSMTASLA MUL_1818|M.ulcerans_Agy99 TVAGAAREYLKKRDELPAKPLIAQIPVSTRTDQTKEDVGNQISSMTASLA MAV_3352|M.avium_104 LVAGAVRDYLQKRGELPAKPLIAQIPVSTRTDENKDDIGNKVSSMTVSLA MAB_0507|M.abscessus_ATCC_1997 IVAGAVRDYLAKRDEFPDKPLIVQIPVSVRTEETDGVVGNQVSSMTVSLA Mflv_0349|M.gilvum_PYR-GCK LVSGALRSYLKDRGELPAKSLVSQVPVSTR-AQADDTVGNQVNAMTVVLA MSMEG_4297|M.smegmatis_MC2_155 LVSGVLRTFLSHRDELPDNSLVAMVPVSVH-DRSDRPGRNQVSGMFSPLQ Mvan_3601|M.vanbaalenii_PYR-1 LVSGVLRTFLLERGELPESSLVAMVPVSVH-DKSDRPGRNQVSGMFSRLE TH_2477|M.thermoresistible__bu LTSGALRSYLLERDQLPDSPLIAMVPVSVH-DKTDRPGRNHVSGMFSRLE MLBr_01244|M.leprae_Br4923 GLVGALRRYHEALG-VSISTLPMAVPVNVR-TEADVVGSNRFVGVTLAAP *. * : . .. ..* :**..: . . *:. .: Mb1460|M.bovis_AF2122/97 THIEDPAKRLAAIHESTLSAKEMAKALSAHQIMGLTETTPPGLLQLAARA Rv1425|M.tuberculosis_H37Rv THIEDPAKRLAAIHESTLSAKEMAKAPSAHQIMGLTETTPPGLLQLAARA MMAR_2231|M.marinum_M THINDPAERLKAIHESTQNAKEMAKALSAHQIMGLTETTPPGLLHLAARA MUL_1818|M.ulcerans_Agy99 THINDPAERLKAIHESTQNAKEMAKALSAHQIMGLTETTPPGLLHLAARA MAV_3352|M.avium_104 THIEDPGERLRAIHDSTQSAKLMAKALSAHQIMGLTETTPPGLLHLAARA MAB_0507|M.abscessus_ATCC_1997 TDIDDPAERIQAIYEGTQGAKEMARAMSAHQIMGLTDTTPPGLLQLAARA Mflv_0349|M.gilvum_PYR-GCK TDVADPAERIKAIYSYTQGAKEMTKALTAHQIMGYTETTPPGLLALASRA MSMEG_4297|M.smegmatis_MC2_155 THIADPAERLRAIAEANAVAKQHSSAIGATLLQDWTQFAAPAVFGTAMRV Mvan_3601|M.vanbaalenii_PYR-1 TNIEDPATRLKAIAEANSVAKQHSSAIAATLLQDWTQFAAPAVFGAAMRV TH_2477|M.thermoresistible__bu TTIEDPAERLRAIANANSVAKQHSSAIAASLLQDWTQFAAPAVFGVAMRV MLBr_01244|M.leprae_Br4923 LGTNDPAARMQKIRSQMTQRRDEPAMNIIGSLAPLMTVLPASVLDFIVDS **. *: * . : . : ...:: Mb1460|M.bovis_AF2122/97 YTASGLSHNLAPINLVVSNVPGPPFPLYMAGARLDSLVPLGPPVMDVALN Rv1425|M.tuberculosis_H37Rv YTASGLSHNLAPINLVVSNVPGPPFPLYMAGARLDSLVPLGPPVMDVALN MMAR_2231|M.marinum_M YTATGLSHNLAPINLVVSNVPGPQFPLYMAGARLDSLVPLGPPVMDVALN MUL_1818|M.ulcerans_Agy99 YTATGLSHNLAPINLVVSNVPGPQFPLYMAGARLDSLVPLGPPVMDVALN MAV_3352|M.avium_104 YTASGLSRNLAPINLVVSNVPGPPFPLYMAGAKLDSLVPLGPPVMDVALN MAB_0507|M.abscessus_ATCC_1997 YTASGLSRNLAPINLVLSNVPGPSFPLYMAGARLESMIPLGPPVMDVALN Mflv_0349|M.gilvum_PYR-GCK YAASGIGSNIAPMNVVISNVPGPTFPLYLGGARVEHLMPVGPLLFDVALN MSMEG_4297|M.smegmatis_MC2_155 YAASRLSGAKPVHNLVVSNVPGPQVPLYFLGAEVKAMYPLGPIFHGSGLN Mvan_3601|M.vanbaalenii_PYR-1 YASSRLSGARPVHNLVISNVPGPQGPLYMLGCEVKAMYPLGPIFHGSGLN TH_2477|M.thermoresistible__bu YAASRLGEAKPVHNLVVSNVPGPQVPLYFLGAEVKAMYPLGPIFHGSGLN MLBr_01244|M.leprae_Br4923 VASS---------DVNASNIPAYPGDTYFAGAKILRQYGIGP-RPGVAMM ::: :: **:*. *: *..: :** . .: Mb1460|M.bovis_AF2122/97 ITCFSYQDYLDFGLVTTPEVANDIDEMADAIEPALAELERAAE------- Rv1425|M.tuberculosis_H37Rv ITCFSYQDYLDFGLVTTPEVANDIDEMADAIEPALAELERAAE------- MMAR_2231|M.marinum_M ITCFSYQEHLDFGFVTTPEVANDIDEMADLIEPALAELERAAGL------ MUL_1818|M.ulcerans_Agy99 ITCFSYQEHLDFGFVTTPEVANDIDEMADLIEPALAELERAAGL------ MAV_3352|M.avium_104 ITCFSYTDYLDFGFVTTPEVANDIDDMADRIEPALTDLEKAAAGETG--- MAB_0507|M.abscessus_ATCC_1997 ITCFSYLEHMDFGFVTTPEVAADIDEMADGLEAALVELEHAVGI------ Mflv_0349|M.gilvum_PYR-GCK VTCFSYCGAVDFGFITTPEIAADIVDLADQIEPALHDLEVAAGLVSDPTR MSMEG_4297|M.smegmatis_MC2_155 ITVMSLTGKLDVGIISCPELLPDLWDMADDFAVALDELLDATKRA----- Mvan_3601|M.vanbaalenii_PYR-1 MTVMSLSGKLDVGIVSCPELLPDLWDMADTFGVALQELLDATR------- TH_2477|M.thermoresistible__bu ITVMSLTGRLNVGMVSCPELMPDLWELAEGFERALRELLDTVG------- MLBr_01244|M.leprae_Br4923 AVLMSRGGFCTVTVRYDRASVKSEALFARCLLEGFDEVLALAGDPTPHAV . :* . . . :* : .: :: . Mb1460|M.bovis_AF2122/97 ------------------- Rv1425|M.tuberculosis_H37Rv ------------------- MMAR_2231|M.marinum_M ------------------- MUL_1818|M.ulcerans_Agy99 ------------------- MAV_3352|M.avium_104 ------------------- MAB_0507|M.abscessus_ATCC_1997 ------------------- Mflv_0349|M.gilvum_PYR-GCK PKPRKRGRR---------- MSMEG_4297|M.smegmatis_MC2_155 ------------------- Mvan_3601|M.vanbaalenii_PYR-1 ------------------- TH_2477|M.thermoresistible__bu ------------------- MLBr_01244|M.leprae_Br4923 PASFAARSSGSPAGWLSSS