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IAQLTTLDAGLRRAQEPDWDASLAIGAVAVINGAVPDFELLKTTLAQRLRSIPRHAQVLRTQWIDQPEFD FDAHIQRAALPGPGDEAELFRAIAHALERPLDLDRPLWECWVIEGLEHNRWAILLKLHHSMADGISAVQI LTRLCDDADHTGVNHVAVKPVPDSDAGARSWPDSLATNIVKAAARAVSWPTMWLSSADSPITMRHYTAVR FALADVDRVCRKFGVTANDVALAAISEGFRTMLLHRGEQPRADSLRTLEKPANQISALLPYLPVDQNDPI TRLRTVHSQLNPAPAAVRTKSASLADYTPLALCTKAIQTLVRLPQRSVVTLATDAPAPRHRLQLMGQPME QVLPIPPTALQLSTGVAVLCYDDELVFGITADYQAATDLRQLAAGIERGMAQLVALSQDSVLLFGKDRRK RRHRSRPGGVARRTLVSPARVRR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_1157 | - | - | 100% (444) | hypothetical protein MMAR_1157 |
| M. marinum M | MMAR_1519 | - | 9e-98 | 44.78% (460) | hypothetical protein MMAR_1519 |
| M. marinum M | MMAR_3406 | - | 6e-86 | 41.15% (452) | hypothetical protein MMAR_3406 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3406 | - | 1e-148 | 61.86% (451) | hypothetical protein Mb3406 |
| M. gilvum PYR-GCK | Mflv_4977 | - | 2e-92 | 41.63% (454) | hypothetical protein Mflv_4977 |
| M. tuberculosis H37Rv | Rv3371 | - | 1e-148 | 61.64% (451) | hypothetical protein Rv3371 |
| M. leprae Br4923 | MLBr_01244 | - | 3e-16 | 23.10% (277) | hypothetical protein MLBr_01244 |
| M. abscessus ATCC 19977 | MAB_3551c | - | 5e-36 | 26.37% (474) | hypothetical protein MAB_3551c |
| M. avium 104 | MAV_4336 | - | 1e-112 | 50.78% (447) | acyltransferase, ws/dgat/mgat subfamily protein |
| M. smegmatis MC2 155 | MSMEG_5242 | - | 3e-96 | 44.02% (443) | acyltransferase, ws/dgat/mgat subfamily protein |
| M. thermoresistible (build 8) | TH_2686 | - | 1e-39 | 26.91% (472) | PUTATIVE Diacylglycerol O-acyltransferase |
| M. ulcerans Agy99 | MUL_2420 | - | 9e-97 | 44.13% (460) | hypothetical protein MUL_2420 |
| M. vanbaalenii PYR-1 | Mvan_4104 | - | 1e-85 | 41.36% (457) | hypothetical protein Mvan_4104 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3406|M.bovis_AF2122/97 ----------MAQLTALDAGFLKSRDPERHPGLAIGAVAVVNGAAPSYDQ
Rv3371|M.tuberculosis_H37Rv ----------MAQLTALDAGFLKSRDPERHPGLAIGAVAVVNGAAPSYDQ
MMAR_1157|M.marinum_M ---------MIAQLTTLDAGLRRAQEPDWDASLAIGAVAVINGAVPDFEL
MAV_4336|M.avium_104 ----------MAQT--LDTAFLKAHDPDQHASLAIGAVAIVDGTVPDPAQ
Mflv_4977|M.gilvum_PYR-GCK ----------MERMTAFDAGFLDAEDADRHVSLAVGAVSVVDGPMPDFDE
Mvan_4104|M.vanbaalenii_PYR-1 ----------MEHLSTLDASFLQAEDSDPHVSLAVGAVSIIEGPAPDYDD
MSMEG_5242|M.smegmatis_MC2_155 -------MTAPEQLSVLDAGFLEAEDSDPNVSLAIGAVAVMAGPMPDFET
MUL_2420|M.ulcerans_Agy99 ----------MNHLTTLDSGFLKAEDVDPRVSLAIGGLAVIEGPVPEQHD
MAB_3551c|M.abscessus_ATCC_199 --MGKAARIVVSRLSALDASFYSSEDSATPMHVGSLAIIRRPRGGFTYEE
TH_2686|M.thermoresistible__bu ---------MVTRLSASDADFFHLEDTSTPMYVGSLAILRRPRGGLSYET
MLBr_01244|M.leprae_Br4923 MADSVEGIGPFDELGALDYLLHRG-EANPRTRAGIMAVELLD-TTPDWNR
. * : : . .:
Mb3406|M.bovis_AF2122/97 LKTVLTERIKSIPRCTQVLAT--------EWIDYPGFDLTQHVRRVALPR
Rv3371|M.tuberculosis_H37Rv LKTVLTERIKSIPRCTQVLAT--------EWIDYPGFDLTQHVRRVALPR
MMAR_1157|M.marinum_M LKTTLAQRLRSIPRHAQVLRT--------QWIDQPEFDFDAHIQRAALPG
MAV_4336|M.avium_104 LEHLVAERILPIARCTQLLRAHPLNR---EWVDCPDFDLAWHLRRVAIAG
Mflv_4977|M.gilvum_PYR-GCK IVAAIGEKIVTIPRLRQVVRRQPLDLSAPEWVEDPTLDLAHHIRRAALPH
Mvan_4104|M.vanbaalenii_PYR-1 LVAAFAERAQGIPRCTQIVHTRPFDLAAPEWVDDPHFDIAHHLHRIALPA
MSMEG_5242|M.smegmatis_MC2_155 LKATLAERILSVPRLRQVLHTRPLDLGAPEWVDDPHLDITRHIRRAALPR
MUL_2420|M.ulcerans_Agy99 LVSVFSERIRACPRFAQRLRRYPFDLGAPQWVDDPDFDIARHVRRVALPH
MAB_3551c|M.abscessus_ATCC_199 LLALVESRLPQVPRYRQKVKEIGFGLARPVWLDDVDFDITYHIRRSALPS
TH_2686|M.thermoresistible__bu LLATVEQRLPQIPRYRQKVRKAPIGLARPVWVDDPDFDITYHVRRSALPS
MLBr_01244|M.leprae_Br4923 FRSRIEDVSQRVLRLRQKVVVPTLPTAAPRWVVDPDFELDFHVRRVRVPD
: . . * * : *: ::: *::* :.
Mb3406|M.bovis_AF2122/97 PGDEAELFRAIALALERPLDPDRPLWECWIIEGLNGNRWAILIKIHHCMA
Rv3371|M.tuberculosis_H37Rv PGDEAELFRAIALALERPLDPDRPLWECWIIEGLNGNRWAILIKIHHCMA
MMAR_1157|M.marinum_M PGDEAELFRAIAHALERPLDLDRPLWECWVIEGLEHNRWAILLKLHHSMA
MAV_4336|M.avium_104 TGDEAELSRVIGQALRRPLDPGRPPWECWVIEGLRGNRWAMLMKTHHGLL
Mflv_4977|M.gilvum_PYR-GCK PGDDDALFRFTAEAMEPRLDRERPLWQAWIIEGLADDRWAILMKVHHCIA
Mvan_4104|M.vanbaalenii_PYR-1 PGDDAEMFTTIAGIMERRLDRDRPLWECWIIEGLADGRWATLMKIHHCIA
MSMEG_5242|M.smegmatis_MC2_155 PGDDAALHDWVAEVMERRLDRDHPLWQCWVADGLPANRWAILIKIHHCVA
MUL_2420|M.ulcerans_Agy99 PGDDDALYRLVADVMGRRLDRDRPLWELWVIEGLAGERWAMLTKVHHCMA
MAB_3551c|M.abscessus_ATCC_199 PGSDGQLQDLVARLTSRPLDRSRPLWEMYLVEGLSKNRLAIYTKTHQALV
TH_2686|M.thermoresistible__bu PGSDAQLHELIARLASRPLDKTRPLWEMYLIEGLAKNRLALYTKSHQALV
MLBr_01244|M.leprae_Br4923 PGTLREVFDLAEVIQQSPMDVSRPLWTATLVEGLAAGRAAMLLQISHAIT
.* : :* :* * : :** * * : : :
Mb3406|M.bovis_AF2122/97 GAMSAAHLLARLCDDADGSAFANNVDIKQIP-PY-------------GDA
Rv3371|M.tuberculosis_H37Rv GAMSAAHLLARLCDDADGSAFANNVDIKQIP-PY-------------GDA
MMAR_1157|M.marinum_M DGISAVQILTRLCDDADHTG-VNHVAVKPVPDSD-------------AGA
MAV_4336|M.avium_104 DGNPAARLITRLCDDADADMFANNAAAQPVS-----------------SP
Mflv_4977|M.gilvum_PYR-GCK DGIAAMHMLAGLSDDGEGETYAGAIRAAHEAGASRPALPS-----PTLNP
Mvan_4104|M.vanbaalenii_PYR-1 DGIATAQMLAKLSDDGAGETFAADIRAAQESGPSILGLLR-----PRLNP
MSMEG_5242|M.smegmatis_MC2_155 DGVAAAHLLTRLCDDSPEPSVPHAPPPAPRQAP------------FSLNP
MUL_2420|M.ulcerans_Agy99 DGIAATHILTGLCDRDGGGAADGSARCRAAQRPK-----T-----AAARP
MAB_3551c|M.abscessus_ATCC_199 DGNSALSLGQVIFDRTARTPDFGEDIWVPEHEPSTSELVAGAVSEWLARP
TH_2686|M.thermoresistible__bu NGMTAPEIGHVIADRTQKPPQFGEDIWMPGREPGTAQLLIGAIGDWLTRP
MLBr_01244|M.leprae_Br4923 DGVGSVEMFAEMYDLERDPPSRPRSPQPIPQDLSRNDLMLQG---INHLP
.. : : : * .
Mb3406|M.bovis_AF2122/97 RSWAETLWRMSVSIAGAVCTAAAR------AVSWP--------AVTSPAG
Rv3371|M.tuberculosis_H37Rv RSWAETLWRMSVSIAGAVCTAAAR------AVSWP--------AVTSPAG
MMAR_1157|M.marinum_M RSWPD-------SLATNIVKAAAR------AVSWPT-------MWLSSAD
MAV_4336|M.avium_104 TGWLD---------ALSRVSSLTG------GLLGAL-------RLAGRAE
Mflv_4977|M.gilvum_PYR-GCK VRWARAGWNATTAVAATAAMTVEGAIGILSGLVR-N-------AESSLNG
Mvan_4104|M.vanbaalenii_PYR-1 LDWMNGAWRATLAAAGAAEHAVVGAAELTARVLTPG-------QESSLNG
MSMEG_5242|M.smegmatis_MC2_155 VDWVTGAWRTAMDVTGIAGKVLHGAGEIVSGLLT-P-------APSSLTG
MUL_2420|M.ulcerans_Agy99 RSGLSGLWNAPAAIASGVVRLAQGSGELVTGLLT-P-------VASALTG
MAB_3551c|M.abscessus_ATCC_199 GARLEAVRNTVADVASLTGEIGELGERMVKVVRTAA-------RGAAPRG
TH_2686|M.thermoresistible__bu GAQMIAVRDNVLGMATNAGELVDAGRRALSVARTVA-------RGTAPSS
MLBr_01244|M.leprae_Br4923 VALAGGVVGGLSGVASVAGRAILRPASTVSGVVGYVRSGIRVLSQAAEPS
: .
Mb3406|M.bovis_AF2122/97 PVTT----RRRYQAVRVPRDAVDAVCHKFGVTANDVALAAITEGFRTVLL
Rv3371|M.tuberculosis_H37Rv PVTT----RRRYQAVRVPRDAVDAVCHKFGVTANDVALAAITEGFRTVLL
MMAR_1157|M.marinum_M SPIT----MRHYTAVRFALADVDRVCRKFGVTANDVALAAISEGFRTMLL
MAV_4336|M.avium_104 AVAP----VRRYATVRVPIADVDRVCRKFGVSANDVALAAVTEGFRTVLL
Mflv_4977|M.gilvum_PYR-GCK PVTT----MRRYSAVQVPLATVASVCQAFDVTLNDVALAAITDSFRSALK
Mvan_4104|M.vanbaalenii_PYR-1 PVTG----MRRYSAAVVDLAVMKQVSRNFDVTLNDVALAAITNGYRHMLL
MSMEG_5242|M.smegmatis_MC2_155 PVTA----RRRFAAAEVSLADVARVCERFDVTVNDVALAAITASFRSMLI
MUL_2420|M.ulcerans_Agy99 PLSD----LRRFSGARVPMADLELVCETFDVTINDVALAAITESYRNVLL
MAB_3551c|M.abscessus_ATCC_199 PLNQRVSRSRRFGVVSTKLADYRRVRAKYDCDVNDVVLATIAGALRNWLM
TH_2686|M.thermoresistible__bu PLNTRVSRNRRFTVARHRLDDYRKVRARYDCDVNDVVLAVIAGALRNWLL
MLBr_01244|M.leprae_Br4923 PLLRQRSLATRTEAIEIQLSDLHKAAKAGDGSINDAYLAGLVGALRRYHE
. : . . **. ** : . *
Mb3406|M.bovis_AF2122/97 HRGQ-QPRADSLRTLEK-----------------TDGSSAMLPYLPVEYD
Rv3371|M.tuberculosis_H37Rv HRGQ-QPRADSLRTLEK-----------------TDGSSAMLPYLPVEYD
MMAR_1157|M.marinum_M HRGE-QPRADSLRTLEKP----------------ANQISALLPYLPVDQN
MAV_4336|M.avium_104 DRGE-QPRADSLRTLVP-----------------LPVRSAVLSHLPVEHD
Mflv_4977|M.gilvum_PYR-GCK RRGE-EPRRDSLRTLVPVSVRS-----DDARDRLDNRVSVMLPHLPVDEP
Mvan_4104|M.vanbaalenii_PYR-1 DRGE-SPGPHALRTLVPVSMRS-----AGDFDVTDNRVSAMLPLLPVDEP
MSMEG_5242|M.smegmatis_MC2_155 ARGV-APGPNALPTLVPVSVRPP----AGAGNDRANQVSVMLPNLPVDQA
MUL_2420|M.ulcerans_Agy99 ARGQ-QPQQGSLRTLVPVSVRA-----DNAFDKTDNRVSAMLPNLPVDEE
MAB_3551c|M.abscessus_ATCC_199 SRGEPVTTASTIRAMVPMSVYRDGDLDVGGEGAATTEVSPFLVDLPVGEG
TH_2686|M.thermoresistible__bu SRGEQVSSTATVRAMAPLSVQSDAELDSTAPGQAVSDVVPFLIDLPVGER
MLBr_01244|M.leprae_Br4923 ALGV---SISTLPMAVPVNVRT------EADVVGSNRFVGVTLAAPLGTN
* :: . *:
Mb3406|M.bovis_AF2122/97 DPVRRLRTVH---NRSQQSGRR----QPDSLSDYTPLMLCAKMIHALARL
Rv3371|M.tuberculosis_H37Rv DPVRRLRTVH---NRSQQSGRR----QPDSLSDYTPLMLCAKMIHALARL
MMAR_1157|M.marinum_M DPITRLRTVHSQLNPAPAAVRT----KSASLADYTPLALCTKAIQTLVRL
MAV_4336|M.avium_104 DPVRRLQTVHARCNPAAGTQPAG---IVESAIGLVPNMVRGNLIQLLSRL
Mflv_4977|M.gilvum_PYR-GCK DPVEQLRTVHRRLNRAKSSGQRQAGTAAVAAVKLIPFALATRAIRAVTSL
Mvan_4104|M.vanbaalenii_PYR-1 DPVRQLEIVHRRLSRAKGSGQREGGDAVLAAAGNIPFALSAWTIRLLTRL
MSMEG_5242|M.smegmatis_MC2_155 DPVAQLQAVHTRLSKAKASGQRQAGSALVTMAAAVPFPLTAWAVRALTRL
MUL_2420|M.ulcerans_Agy99 DPVQRLRKVHARLGQTKASGQPRAGNLFLSLADRIPFALTAWTVGVLMRL
MAB_3551c|M.abscessus_ATCC_199 NTVVRLSQIAHATESHSAAFSLVDVPNMAALSGFVPPTLHALAARVASTL
TH_2686|M.thermoresistible__bu NPVVRLSQISHATETHPTASSLVDARTIVTLTGFAPATLHAMGVRVATNF
MLBr_01244|M.leprae_Br4923 DPAARMQKIRSQMTQRRDEPAMNIIGSLAPLMTVLPASVLDFIVDSVASS
:. :: : . * :
Mb3406|M.bovis_AF2122/97 PQQGIVTLATSAPGPRHQLRLMGQKMDQVLPIPPTALQLSTGVAVLSYGD
Rv3371|M.tuberculosis_H37Rv PQQGIVTLATSAPRPRHQLRLMGQKMDQVLPIPPTALQLSTGIAVLSYGD
MMAR_1157|M.marinum_M PQRSVVTLATDAPAPRHRLQLMGQPMEQVLPIPPTALQLSTGVAVLCYDD
MAV_4336|M.avium_104 PQRAVVTLATNVPGPRRRLRVMGQTLERLLPVPPTATQLHTGVAVLSYGD
Mflv_4977|M.gilvum_PYR-GCK PQHGVVTLATNVPGPQHRLQVMGREVVRMFPVPPMALRLRTAVAILSYGD
Mvan_4104|M.vanbaalenii_PYR-1 PQRSVTALATNVPGPRGRQRVLGRKVVEILPIPPIALHLRTGIAMLSYAG
MSMEG_5242|M.smegmatis_MC2_155 PQRGVAMLATNVPGPRRRVTILGREVIRLLPVPPIAMRMRTAVAILSYAD
MUL_2420|M.ulcerans_Agy99 PQRGVATVATNVPGPRQPLQIMGRPVAAVFPVPPLAMHLRTGVAMLSYSD
MAB_3551c|M.abscessus_ATCC_199 PNRLFNLLVTNVPGPQAPMYLGGARLAEIYPVPPLLRNQVLSIGLTSYNG
TH_2686|M.thermoresistible__bu SARQFNLLITNVPGAQKQMYIAGTKMLESYSVPPLLRNQVLAVAVTSYHG
MLBr_01244|M.leprae_Br4923 DVN-----ASNIPAYPGDTYFAGAKILRQYGIGPRPG-VAMMAVLMSRGG
. :. * . * : : * : . .
Mb3406|M.bovis_AF2122/97 ELVFGITADYDAASEMQQLVNGIELGVARLVALSDDSVLLFTKDRRKRSS
Rv3371|M.tuberculosis_H37Rv ELVFGITADYDAASEMQQLVNGIELGVARLVALSDDSVLLFTKDRRKRSS
MMAR_1157|M.marinum_M ELVFGITADYQAATDLRQLAAGIERGMAQLVALSQDSVLLFGKDRRKRRH
MAV_4336|M.avium_104 ELVFGITAGPGDGFDVTRLAAAVELGMARLAALGDDSVLLFADRRRRRAA
Mflv_4977|M.gilvum_PYR-GCK DLVFGITTDFDAFPDVDELAAGIGAAVDTLAAAA--------RPL-----
Mvan_4104|M.vanbaalenii_PYR-1 RFSFGITADYDSAPDVDALARGIGEGVRCLAELG--------RAERRTPP
MSMEG_5242|M.smegmatis_MC2_155 HLAFGIISDYDAEIDVDAVAAGIEQAVARLAQIA--------VAHIRSTP
MUL_2420|M.ulcerans_Agy99 DLYFGILTDYNPVADVDQLARGTEAAVARLVAIS--------KRRKARRG
MAB_3551c|M.abscessus_ATCC_199 TVYYGINADREAMPDADMLPLLITEALDELLEAAQ---------------
TH_2686|M.thermoresistible__bu MLYYGVNADRDAMSDVEVLPSLLSESLDELLEAAQ---------------
MLBr_01244|M.leprae_Br4923 FCTVTVRYDRASVKSEALFARCLLEGFDEVLALAGDPTPHAVPASFAARS
: . . . .. : .
Mb3406|M.bovis_AF2122/97 RALPSAARRGRPSVPTARARH
Rv3371|M.tuberculosis_H37Rv RALPSAARRGRPSVPTARARH
MMAR_1157|M.marinum_M RSRPGGVAR-RTLVSPARVRR
MAV_4336|M.avium_104 RSPLGRVPPAHPSAP-GHARH
Mflv_4977|M.gilvum_PYR-GCK ---------------------
Mvan_4104|M.vanbaalenii_PYR-1 DGAGRPIADAP----------
MSMEG_5242|M.smegmatis_MC2_155 LGTLALVPGELA---------
MUL_2420|M.ulcerans_Agy99 RGPLSLVV-------------
MAB_3551c|M.abscessus_ATCC_199 ---------------------
TH_2686|M.thermoresistible__bu ---------------------
MLBr_01244|M.leprae_Br4923 SGSPAGWLSSS----------