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SAATDLYAVHQALAGESRAIPTGSCPTVGVAGLTLGGGLGADSRHAGLTCDALKSATVVLPGGDAVSASA DDHAELFWALRGGGGGNFGVTTSMTFARFPTADCDVVRVDFAPSAAAQVLVG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3352c | - | - | 100% (123) | POSSIBLE OXIDOREDUCTASE |
| M. tuberculosis H37Rv | Rv0063 | - | 1e-47 | 71.54% (123) | oxidoreductase |
| M. tuberculosis H37Rv | Rv1726 | - | 3e-17 | 40.00% (120) | oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3387c | - | 1e-67 | 100.00% (123) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_4651 | - | 1e-12 | 40.82% (98) | FAD linked oxidase domain-containing protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2456 | - | 5e-26 | 46.28% (121) | hypothetical protein MAB_2456 |
| M. marinum M | MMAR_1179 | - | 4e-52 | 77.24% (123) | oxidoreductase |
| M. avium 104 | MAV_0089 | - | 4e-43 | 64.23% (123) | FAD binding domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_1746 | - | 9e-13 | 45.16% (93) | 6-hydroxy-D-nicotine oxidase |
| M. thermoresistible (build 8) | TH_1540 | - | 1e-10 | 35.87% (92) | PROBABLE OXIDOREDUCTASE |
| M. ulcerans Agy99 | MUL_1431 | - | 1e-51 | 76.42% (123) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_4048 | - | 3e-22 | 44.54% (119) | FAD linked oxidase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4651|M.gilvum_PYR-GCK ---------------------------------MTVPTDLRRDEALRSLR
MSMEG_1746|M.smegmatis_MC2_155 -------------------------------------MLQVHPTMVDELA
Rv3352c|M.tuberculosis_H37Rv --------------------------------------------------
Mb3387c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1179|M.marinum_M --------MISRQTLLRGAAAATAAGLGSALFGSARAVAEP-VSGWSALA
MUL_1431|M.ulcerans_Agy99 --------MISRQTFLRGAAAATAAGLGSALFGSARAVAEP-VSGWSALA
MAV_0089|M.avium_104 -----MAREISRQTFLRGAVGALAAG---AMLGAPRVGADPRPSGWEGLS
MAB_2456|M.abscessus_ATCC_1997 MDPQSRPALMTRRTVLSAGAMLALGSTSLIGCSPVLPNEIPAGVRWEDLR
Mvan_4048|M.vanbaalenii_PYR-1 -----------------------------MGGSHATAQPPPTQAALADLT
TH_1540|M.thermoresistible__bu ------------------------------------------------MA
Mflv_4651|M.gilvum_PYR-GCK DQVATPVALP-GEPGY-ERCRPWN-VVAPVEPAAVVLATSPEDVAGTVRF
MSMEG_1746|M.smegmatis_MC2_155 MSMPERVHLP-GSPEYGDAVAIWN-GAVTERPAAVVRPTSSGDVRNVVRF
Rv3352c|M.tuberculosis_H37Rv --------------------------------------------------
Mb3387c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1179|M.marinum_M SSIGGRVLLPSNGASFTSGKQVFNSLYNNSNPAAVVTVTSQADVEKAVAF
MUL_1431|M.ulcerans_Agy99 SSIGGRVLLPSNGASFTSGKQVFNSLYNNSNPAAVVTVTSQADVEKAVAF
MAV_0089|M.avium_104 TALGGKVLLP-DSPQFAGAKQVFNTNYNGSTPAAVVTPTSAADVQKAMAF
MAB_2456|M.abscessus_ATCC_1997 RSLSG-ALVVRGDAAMDESGRAFNPLFDVNHPGAVAFCASDQDVARCVEF
Mvan_4048|M.vanbaalenii_PYR-1 RTLRGSVIGP-DGGRFTELATPRNLRFAATMPRAVVLCADADDVAKTVLW
TH_1540|M.thermoresistible__bu ALPALSFRRGAQGYEQARRTTVWNGLLPDRFPDVIVQAVTVDDVVTAVRY
Mflv_4651|M.gilvum_PYR-GCK AAAHGFRVTVQATGHGAVG--VGPDTILIQTSAMRHVSVDVVNG-TARVG
MSMEG_1746|M.smegmatis_MC2_155 AHEQRIPITVRAGGHDWGGRALNEGGLVIDLSSMRKVYIDPAAR-EALVE
Rv3352c|M.tuberculosis_H37Rv ------------------------------------------------MS
Mb3387c|M.bovis_AF2122/97 ------------------------------------------------MS
MMAR_1179|M.marinum_M AAANKLKIAPRGGGHSYIGASTAVGAMVIDLRGLPGGVNFDAGSGTVTVP
MUL_1431|M.ulcerans_Agy99 AAANKLKIAPRGGGHSYIGASTAVGAMVIDLRGLPGGVNFDAGSGTVTVP
MAV_0089|M.avium_104 AAAHNLKVAPRSGGHSYTGASTANGTMVLDLRQLPGDANYDAATGQVTVT
MAB_2456|M.abscessus_ATCC_1997 ATSARLPIAARGGGHSYAAYCIPNDGLVVDLARMAAVS---VTGTRAVVG
Mvan_4048|M.vanbaalenii_PYR-1 ARNTGTSFAIRGGGHNYAEASSSRG-VIISTRQMTAATIDGATLRAHAGV
TH_1540|M.thermoresistible__bu AADNDLRIGVCSGGHSWAASHLRDGGMLLDVSRLDHCGID-ADRMVAVAG
Mflv_4651|M.gilvum_PYR-GCK AGARWQDVLDVATPHGLAPLCGSAPGVGVIGYLTGGGIGPLVRTYGLSSD
MSMEG_1746|M.smegmatis_MC2_155 GGATAEDVVQAAERHGLTAAAPNLADVGFTGFTLGGGYGPLNGIAGLGVD
Rv3352c|M.tuberculosis_H37Rv AATDLYAVHQALAGESRAIPTGSCPTVGVAGLTLGGGLGADSRHAGLTCD
Mb3387c|M.bovis_AF2122/97 AATDLYAVHQALAGESRAIPTGSCPTVGVAGLTLGGGLGADSRHAGLTCD
MMAR_1179|M.marinum_M AGVSLTDVHQVLAGAGRAIPTGSCPTVGVGGLALGGGMGADSRHAGLTCD
MUL_1431|M.ulcerans_Agy99 AGVSLTDVHQVLAGAGRAIPTGSCPTVGVGGLALGGGMGADSRHAGLTCN
MAV_0089|M.avium_104 PATSLYTMHRTLAAVGRGVPTGTCPSVGAAGHALGGGMGAQSRHAGLLCD
MAB_2456|M.abscessus_ATCC_1997 AGARLIDVYAGIAGAGRMLAGGSCPTVGIAGLTLGGGVGVLTRRFGLTCD
Mvan_4048|M.vanbaalenii_PYR-1 RNADLAALLPQGGGGRLLLPGGNCPGVGVVGLTLGGGIGPNAPWAGLTAD
TH_1540|M.thermoresistible__bu PGKIGSELAGELDKLDLFFPAGHCEGICLGGYLLQGGYGWNSRVLGPACE
: : * ** * * :
Mflv_4651|M.gilvum_PYR-GCK HVRSFDVVTGGGRLLRAAPDENADLFWGLRG-GKATLGIVTSAEIDLLPV
MSMEG_1746|M.smegmatis_MC2_155 NLLEAHVVLADGRSVTANAADEADLLWALRG-GGANFGVVTHLRVRLHPV
Rv3352c|M.tuberculosis_H37Rv ALKSATVVLPGGDAVSASADDHAELFWALRGGGGGNFGVTTSMTFARFPT
Mb3387c|M.bovis_AF2122/97 ALKSATVVLPGGDAVSASADDHAELFWALRGGGGGNFGVTTSMTFARFPT
MMAR_1179|M.marinum_M ALRSATVVLPSGETVTASAEDHPDLFWALRGGGGGNFGVTTAMTFETFPV
MUL_1431|M.ulcerans_Agy99 ALRSATVVLPSGETVTASAEDHPDLFWALRGGGGGNFGVTTAMTFETFPV
MAV_0089|M.avium_104 QLTSASVVLPSGQAVTASTASNPDLFWALRGGGGGNFGVTTSLTFATFPT
MAB_2456|M.abscessus_ATCC_1997 QLISARVVTADGKIRVVSADTESDLFWAIRGVGGGNFCIATELAFETAAS
Mvan_4048|M.vanbaalenii_PYR-1 RLRKVTMVTAHGDVVTASPTENPDLFWGLRGGAGGNFGVVTDLEYELVEV
TH_1540|M.thermoresistible__bu SIVGVDVVTADGEVLYCDDETNADLFWAARGSGPGFFAVVTSFHLRLHPR
: :* * ..:*:*. ** . . : :.*
Mflv_4651|M.gilvum_PYR-GCK PEFYGGAVYFAAD--DVADVLRAWAAWCVDLPETINTSIAIQQLPPLPEV
MSMEG_1746|M.smegmatis_MC2_155 PHLATGVLMFPWE--QAADVMRRYDALAPSLPDGLTAQIGVIPAP-----
Rv3352c|M.tuberculosis_H37Rv ADCDVVRVDFAPS--AAAQVLVG---------------------------
Mb3387c|M.bovis_AF2122/97 ADCDVVRVDFAPS--AAAQVLVG---------------------------
MMAR_1179|M.marinum_M ADSDVVRVDFTPS--SAAQVLAGWQTWLAAADRDTWGLVDMSVSA-----
MUL_1431|M.ulcerans_Agy99 ADSDVVRVDFTPS--SAAQVLAGWQTWLAAADRDTWGLVDMSVSA-----
MAV_0089|M.avium_104 KDVDAVNLNFPPQ--SFAQVLVGWQNWLRTADPNSWALADATVDA-----
MAB_2456|M.abscessus_ATCC_1997 TDLTVFTLDYAAG--EMAPIVHRWLTFMAGAPDELWTTLHAIGGA-----
Mvan_4048|M.vanbaalenii_PYR-1 PVRRATTAELSVTGADAATRVALAFQQLRADAERIVTGNLYLGHA-----
TH_1540|M.thermoresistible__bu PPVCGSCLYIYPA-EAIDDVYTWALTSGRDVDDRVELQIIASRDLPALG-
Mflv_4651|M.gilvum_PYR-GCK PEPLAGRMTVAVRYAAVGDVDEAEQALAPMRAVATPVLDTVGVLPYAAIG
MSMEG_1746|M.smegmatis_MC2_155 ----DGGPVVFVAPYWVGDPDEGDRWVAELRRLGTPVVDQVAPMSPSAQL
Rv3352c|M.tuberculosis_H37Rv --------------------------------------------------
Mb3387c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1179|M.marinum_M ----AQANCHVLATCPAGAGRGVADAIKSAVGAQPTGIETKTFNHMELVK
MUL_1431|M.ulcerans_Agy99 ----AQANCHVLATCPAGAGRGVADAIKSAVGAQPTGIETKTFNHMELVK
MAV_0089|M.avium_104 ----MGVHCRILATCPAGSGNSAAAAITQAVGIQPSGVETHTFNYMDLVN
MAB_2456|M.abscessus_ATCC_1997 ----IPQCRIVGCVAQGVNSQDVIESLRGGIGVRAADSFIAEMTFLDAMK
Mvan_4048|M.vanbaalenii_PYR-1 ----AGDVEAALTTQLLVDEADARDLLAPLTAIPGLTAEITEQPWWGAYA
TH_1540|M.thermoresistible__bu ---LNQPSIVVASPVFAESESAAAQALAVLGDCPAVDRAIIKIPYATTDL
Mflv_4651|M.gilvum_PYR-GCK A-VHADPVDPMPINED--------------QALLRELPPEAVEALLAAAG
MSMEG_1746|M.smegmatis_MC2_155 R-LLDPLVPRGRHYEM--------------RTVNVDTLSPGVIDALVAAG
Rv3352c|M.tuberculosis_H37Rv --------------------------------------------------
Mb3387c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1179|M.marinum_M Y-LAGGSSASSPRGFVAGSD-----------VIGTVNSAAAQAIVAAVGK
MUL_1431|M.ulcerans_Agy99 Y-LAGGSSASSPRGFVAGSD-----------VIGTVNSAAAQAIVAAVGK
MAV_0089|M.avium_104 Y-LAVGNLNPQPLGYVGGSD-----------VFPTVNAAVAQGIAAAVNA
MAB_2456|M.abscessus_ATCC_1997 F-MGGCTTLTVAQCHPSWTGPGSGQLKREAFVASSRMVPHPDVDTARIET
Mvan_4048|M.vanbaalenii_PYR-1 W-YVTPPSPAYPFWDRSLYAD--------QFLSGDALAAALEVVRRFPAG
TH_1540|M.thermoresistible__bu AGWYGAIMTNYPTGHRYATDN----------MWTSASPEALLPGIHRIIE
Mflv_4651|M.gilvum_PYR-GCK PESGSPQAIVELRHLGGALAREATHRSAFCHRNAAFSLAVIGVPAPEIAD
MSMEG_1746|M.smegmatis_MC2_155 SSRTSPASVLALHHFHGASTRVGLTDTAFGLRTPHFLVEIVAAWDADSDD
Rv3352c|M.tuberculosis_H37Rv --------------------------------------------------
Mb3387c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1179|M.marinum_M WPPASGRASALVDTLTGAVGDIDPTATAFPWRRQSAVVQWYVETPSSGQT
MUL_1431|M.ulcerans_Agy99 SPPASGWASALVDTLTGAVGDIDPTATAFPWRRQSAVVQWYVETPSSGQT
MAV_0089|M.avium_104 FPRNAGRMLAIMHALDGALATVAPAATAFPWRRQSALVQWYVET--SGDP
MAB_2456|M.abscessus_ATCC_1997 LLAGKPGLTFIFDSLGGAVRRISPDATAFPHRQAAACIQIYHGVG--ADP
Mvan_4048|M.vanbaalenii_PYR-1 NDPERYGALGLYGWVGGAVNDVAPDATAYVHRTARILVEMSSGWSPAPSG
TH_1540|M.thermoresistible__bu TLPPAPSHFLMFNWSP-----TSTRDNLFYGLEADFNLALYAVWNDPEDD
Mflv_4651|M.gilvum_PYR-GCK MVIAH--------AGAVTGAVAPWSTGGQMPNFAPSYDPARPSRVYTDDT
MSMEG_1746|M.smegmatis_MC2_155 DGERHR-----RWAQSTFDALGAHALPGGYPNLIGPDQRNQADTAYGPNA
Rv3352c|M.tuberculosis_H37Rv --------------------------------------------------
Mb3387c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1179|M.marinum_M AAAT-------KWINSAHQAVQQFS-VGGYVNYLEA--NTAPSRYFGSNL
MUL_1431|M.ulcerans_Agy99 AAAT-------KWINSAHQAVQQFS-VGGYVNYLEA--NTALSRYFGSNL
MAV_0089|M.avium_104 AAAT-------NWLASAHQAVQQYS-VGGYVNYLEA--NQSPARYFGPNL
MAB_2456|M.abscessus_ATCC_1997 AVAH-------ERVSQARDGLGDICGPAAYVNYIDPGMPDWATAYYGDNL
Mvan_4048|M.vanbaalenii_PYR-1 APVAPIPPDIRDWEDELWETVLPHTTGRSYQNFPDPELADWPRAYYGANL
TH_1540|M.thermoresistible__bu ERFS-------AWPGTNMAALAHLAMGVGLA---DENLGRRPARFATDAN
Mflv_4651|M.gilvum_PYR-GCK LHWLAGLADRYDPARTLATGQVIRTVV--
MSMEG_1746|M.smegmatis_MC2_155 ERLLA-AKDRWDAGNVFTAIPLPSRSSTS
Rv3352c|M.tuberculosis_H37Rv -----------------------------
Mb3387c|M.bovis_AF2122/97 -----------------------------
MMAR_1179|M.marinum_M SRLTQ-IRQRYDPSRLMYSGLNF------
MUL_1431|M.ulcerans_Agy99 SRLTQ-IRQRYDPSRLMYSGLNF------
MAV_0089|M.avium_104 SRLSA-VRQKYDPGRVMFSGLNY------
MAB_2456|M.abscessus_ATCC_1997 PRLRG-IAAAYDPKGIFRFAQAVRP----
Mvan_4048|M.vanbaalenii_PYR-1 DRLTR-VKATWDPEDVFRYPQGIPPR---
TH_1540|M.thermoresistible__bu MARLDGIRARRDPAGRFHGWMGRV-----