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SNPQPEKVRVVVGDDHPLFREGVVRALSLSGSVNVVGEADDGAAALELIKAHLPDVALLDYRMPGMDGAQ VAAAVRSYELPTRVLLISAHDEPAIVYQALQQGAAGFLLKDSTRTEIVKAVLDCAKGRDVVAPSLVGGLA GEIRQRAAPVAPVLSAREREVLNRIACGQSIPAIAAELYVAPSTVKTHVQRLYEKLGVSDRAAAVAEAMR QRLLD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0844c | narL | - | 100% (216) | POSSIBLE NITRATE/NITRITE RESPONSE TRANSCRIPTIONAL REGULATORY PROTEIN NARL |
| M. tuberculosis H37Rv | Rv3133c | devR | 5e-24 | 32.02% (203) | two component transcriptional regulatory protein DevR |
| M. tuberculosis H37Rv | Rv1626 | - | 2e-12 | 29.60% (125) | two-component system transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0867c | narL | 1e-116 | 99.54% (216) | nitrate/nitrite response transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_0730 | - | 7e-85 | 75.36% (211) | two component LuxR family transcriptional regulator |
| M. leprae Br4923 | MLBr_01286 | - | 1e-12 | 30.97% (113) | putative two-component response regulatory protein |
| M. abscessus ATCC 19977 | MAB_0060 | - | 2e-84 | 74.76% (210) | nitrate/nitrite response transcriptional regulatory protein |
| M. marinum M | MMAR_4782 | narL | 1e-106 | 93.52% (216) | nitrate/nitrite response regulator protein NarL |
| M. avium 104 | MAV_0872 | - | 7e-84 | 88.46% (182) | DNA-binding response regulator, LuxR family protein |
| M. smegmatis MC2 155 | MSMEG_0105 | - | 1e-86 | 78.10% (210) | DNA-binding response regulator, LuxR family protein |
| M. thermoresistible (build 8) | TH_3563 | - | 6e-36 | 40.93% (215) | PUTATIVE DNA-binding response regulator, LuxR family protein |
| M. ulcerans Agy99 | MUL_0351 | narL | 1e-105 | 92.59% (216) | nitrate/nitrite response regulator protein NarL |
| M. vanbaalenii PYR-1 | Mvan_2836 | - | 2e-30 | 37.86% (206) | two component LuxR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Rv0844c|M.tuberculosis_H37Rv -----MSNPQPEKVRVVVGDDHPLFREGVVRALSLSGSVNVVGEADDGAA
Mb0867c|M.bovis_AF2122/97 -----MSNPQPEKVRVVVGDDHPLFREGVVRALSLSGSVNVVGEADDGAA
MMAR_4782|M.marinum_M -----MDVTKTEKVRVVVGDDHPLFREGVVRALSLSGSVNVVGEADDGAA
MUL_0351|M.ulcerans_Agy99 -----MDVTKTEKVRVVVGDDHPLFREGVVRALSLSGSVNVVGEADDGAA
MAV_0872|M.avium_104 --------------------------------------MNVVGEAEDGSA
Mflv_0730|M.gilvum_PYR-GCK -------MTGPGRVRVVVGDDHPMFRDGVVRALQSSGAIDVVAEADDGTA
MSMEG_0105|M.smegmatis_MC2_155 -----MLTRMSDKVRVVVGDDHPMFREGVVRALTSSGDIDVVAEADNGAD
MAB_0060|M.abscessus_ATCC_1997 -----MQVSG-ELVRVVVGDDHPLFREGVVRALTASGQITVVAEAENGTG
TH_3563|M.thermoresistible__bu -------MGEPQQPTVMVVDDHPIWREAVARDLAEAG-LSVVATADGVAA
Mvan_2836|M.vanbaalenii_PYR-1 ---------------MMVVDDHPIWRDAVARDLADDG-FDVVATADGVAS
MLBr_01286|M.leprae_Br4923 MTGPTTDADAATPHRVLIAEDEALIRLDLAEMLRDEG-YDIVGEAADGQE
:*. * .
Rv0844c|M.tuberculosis_H37Rv ALELIKAHLPDVALLDYRMPGMDGAQVAAAVRSYELPTRVLLISAHDEPA
Mb0867c|M.bovis_AF2122/97 ALELIKAHLPDVALLDYRMPGMDGAQVPAAVRSYELPTRVLLISAHDEPA
MMAR_4782|M.marinum_M ALELIKTHLPDVALLDYRMPRMDGAQVAAAVRSNELPTRVLLISAHDESA
MUL_0351|M.ulcerans_Agy99 ALELIETHLPDVALLDYRMPRMDGAQVAAAVRSNGLPTRVLLISAHDESA
MAV_0872|M.avium_104 ALELIKSHQPDVALLDYRMPGMDGAQVAAAVRADGLATRVLLISAHDESA
Mflv_0730|M.gilvum_PYR-GCK ALAAIREHRPAVALLDYRMPGMDGAEVAAAVQRGALPTRVLLISAHDESA
MSMEG_0105|M.smegmatis_MC2_155 ALELIKVHRPAVALLDYRMPQLDGAQVAAAVVRDELPTRVLLVSAHDESA
MAB_0060|M.abscessus_ATCC_1997 ALELIREHRPDVALVDYRMPELDGTQVAAAVRRDELPTRVLLLSAHDDAA
TH_3563|M.thermoresistible__bu ARRRAAAVRPDVVLMDMRLPDGDGARATAEVRAVSPDSRVLVLSASEERD
Mvan_2836|M.vanbaalenii_PYR-1 AKRRAAVVQPAVVLMDMRLADGDGAQATAEVLAVSPSSRVLVLSASDERD
MLBr_01286|M.leprae_Br4923 AVELAERHKPDLVIMDVKMPRRDGIDAASEIASKRIAP-IVVLTAFSQRD
* * :.::* ::. ** ..: : . :::::* .:
Rv0844c|M.tuberculosis_H37Rv IVYQALQQGAAGFLLKDSTRTEIVKAVLDCAKGRDVVAPSLVGGLAGEIR
Mb0867c|M.bovis_AF2122/97 IVYQALQQGAAGFLLKDSTRTEIVKAVLDCAKGRDVVAPSLVGGLAGEIR
MMAR_4782|M.marinum_M IVYQALQQGAAGFLLKDSTRTEIVKAVLDCAKGRDVVAPSLVGGLAGEIR
MUL_0351|M.ulcerans_Agy99 IVYQALQQGAAGFLLKDSTRTEIVKAVLDCAKGRDVVAPSLVGGLAGEIR
MAV_0872|M.avium_104 IVYQALQQGAAGFVLKDSTRSEIVKAVLDCAQGRDVVAPALVGGLAAEIR
Mflv_0730|M.gilvum_PYR-GCK IVYRALADGAAGFLPKESTRNELITAVLDCAKGRDVVAPSLAAGLAGEIR
MSMEG_0105|M.smegmatis_MC2_155 IVYSALQQGAAGFLSKESTRSELVSAVLSCAKGRDVITPHLAAGLAGEIR
MAB_0060|M.abscessus_ATCC_1997 IVYRALEEGAAGFLSKESTRTELVGAVLDCARGRDVVAASLTAGLAGEIR
TH_3563|M.thermoresistible__bu DVLEAVKAGATGYLVKSASKTELVDAVHATAQGRAVFTPGLAGLVLGEYR
Mvan_2836|M.vanbaalenii_PYR-1 DVLEAVKAGATGYLVKSASKQELGDAVRATAQGRAVFTPGLAGLVLGEFR
MLBr_01286|M.leprae_Br4923 LVERARDAGAMAYLVKPFTISDLIPAIALAMSRFSELT-----ALEREVA
* * ** .:: * : :: *: .: : *
Rv0844c|M.tuberculosis_H37Rv --QRAAPVA---PVLSAREREVLNRIACGQSIPAIAAELYVAPSTVKTHV
Mb0867c|M.bovis_AF2122/97 --QRAAPVA---PVLSAREREVLNRIACGQSIPAIAAELYVAPSTVKTHV
MMAR_4782|M.marinum_M --QRAAPMA---PVLSAREREVLHRIAKGQSIPAIAGELYVAPSTVKTHV
MUL_0351|M.ulcerans_Agy99 --QRAAPMA---PVLSAREREVLHRIAKGQSIPAIAGELYVAPSTVKTHV
MAV_0872|M.avium_104 --QRAEPTG---PVLSAREREVLHRIARGQSIPAIAGELYVAPSTVKTHV
Mflv_0730|M.gilvum_PYR-GCK --RRAEPEG---PALSPREREVLVLIAAGSTIPAMARELFLAPSTVKTHV
MSMEG_0105|M.smegmatis_MC2_155 --RRNEPDV---PVLSPREREVLNLIAQGRSIPAMAKELYLAPSTVKTHV
MAB_0060|M.abscessus_ATCC_1997 --KRAQPAG---PSLSTREREVLRMIAAGQTVPAIARALFLAPSTVKTHV
TH_3563|M.thermoresistible__bu RISRQPGAGPDAPRLTERETEILRYVAKGLTAKQIAAQLSLSHRTVENHV
Mvan_2836|M.vanbaalenii_PYR-1 RIERDSPAG---PTLTERETEILRHVAKGLTAKQIASRLSLSHRTVENHV
MLBr_01286|M.leprae_Br4923 -------------TLADR-LETRKLVERAKGLLQVKQGMTEPEAFKWIQR
*: * * : . : : . :
Rv0844c|M.tuberculosis_H37Rv QRLYEKLGVSDRAAAVAEAMRQRLLD
Mb0867c|M.bovis_AF2122/97 QRLYEKLGVSDRAAAVAEAMRQRLLD
MMAR_4782|M.marinum_M QRLYEKLGVSDRAAAVAEAMRQGLLD
MUL_0351|M.ulcerans_Agy99 QRLYEKLGVSDRAAAVAEAMRQGLLD
MAV_0872|M.avium_104 QRLYEKLGVSDRAAAVAEAMRQGLLS
Mflv_0730|M.gilvum_PYR-GCK QRLYEKLGVSDRGAAVAEAMRRKLLD
MSMEG_0105|M.smegmatis_MC2_155 QRLYEKLGVSDRAAAVAEAMRRHLLD
MAB_0060|M.abscessus_ATCC_1997 QRLYEKLGVGDRAAAVAEAMRRGLLE
TH_3563|M.thermoresistible__bu QATFRKLQVANRVELARYAIEHGLDE
Mvan_2836|M.vanbaalenii_PYR-1 QATFRKLQIGNRVELARYAIEHGLDE
MLBr_01286|M.leprae_Br4923 AAMDRRTTMKRVAEVVLETLDTPKDT
.: : . ::