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TDIEVALPFWLDRPDHEATDVALAAADTGFAALWIGEMATYDAFALATSIGLRTPNMTLKVGPLAVGVRG PVGLALGVSSVASLTGCRVDLALGASSPAIVAGWHGRPWAHHVPVMRETIECLRSIFTGARVEYSGRHVN SRGFRLRGAAPDTRIALGAFGPGMIRLAAQHADEVVLNLASPFRVGRVRAAIDSAAAAAGRAAPRLTVCV PVAVNPGAAAHSQLAAQLAVYLAPPGYGEMFSALGFDGLVRSARSRATRRELAVAVPSELLDRVCALGSP DRVAARLRAYADAGADCVAVVPATAEDPGGRVALRALRPGGLYGTAGDNDGRR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3093c | - | - | 100% (334) | HYPOTHETICAL OXIDOREDUCTASE |
| M. tuberculosis H37Rv | Rv3520c | - | 5e-20 | 25.60% (336) | coenzyme F420-dependent oxidoreductase |
| M. tuberculosis H37Rv | Rv0791c | - | 2e-08 | 22.88% (306) | hypothetical protein Rv0791c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3120c | - | 0.0 | 99.70% (334) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_2453 | - | 2e-17 | 28.99% (307) | luciferase family protein |
| M. leprae Br4923 | MLBr_00348 | - | 1e-21 | 26.22% (328) | putative coenzyme F420-dependent oxidoreductase |
| M. abscessus ATCC 19977 | MAB_1339 | - | 3e-16 | 25.18% (278) | putative monooxygenase (luciferase-like) |
| M. marinum M | MMAR_1557 | - | 1e-139 | 78.33% (323) | oxidoreductase |
| M. avium 104 | MAV_3337 | - | 2e-20 | 25.84% (298) | monooxygenase |
| M. smegmatis MC2 155 | MSMEG_5732 | - | 7e-21 | 27.24% (290) | monooxygenase |
| M. thermoresistible (build 8) | TH_1703 | - | 4e-17 | 24.53% (318) | oxidoreductase |
| M. ulcerans Agy99 | MUL_4782 | - | 3e-24 | 29.90% (311) | coenzyme F420-dependent oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_0261 | - | 3e-18 | 27.96% (304) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Rv3093c|M.tuberculosis_H37Rv ------MTDIEVALP---FWLDRPD--HEATDVALAAADTGFAALWIGEM
Mb3120c|M.bovis_AF2122/97 ------MTDIEVALP---FWLDRPD--HEATDVALAAADTGFAALWIGEM
MMAR_1557|M.marinum_M ------MTDLEVALP---FWLDRPD--DEAMEVALAASNAGFDVLWVGEM
MAV_3337|M.avium_104 -------MSAGIIL---MAHPDAANLVDDVIAQARRAHELGVGQVWLAQQ
MSMEG_5732|M.smegmatis_MC2_155 -----MIMPTGVML---RINPSAANAIDGLIADARRAHDIGVKQIWLAQQ
MAB_1339|M.abscessus_ATCC_1997 -------MKLGVAIGRPLSVQNSTNLVDTFIAHARRVAEAGVRTLWLGQM
Mvan_0261|M.vanbaalenii_PYR-1 -------MQISMFG---QISGLGGNPIDATIAYLSQLRDEGFARVWISQL
Mflv_2453|M.gilvum_PYR-GCK -------MRIGLMVG-SDRERARPDRLAGLIEDGIAAETAGFNSFWFPQV
MLBr_00348|M.leprae_Br4923 MVERANAMKLGLQLG-----YWAAQPPGNAAELVAAAEGAGFDAVFTGEA
TH_1703|M.thermoresistible__bu -------MRIGMQLA-----YSGG--FKETAGLVVELEKVGLDLAVVPEA
MUL_4782|M.ulcerans_Agy99 -------MRTATTVE-----LSGGKDGKDTVDFVVEAEKLGLHTCWVAEA
*. :
Rv3093c|M.tuberculosis_H37Rv -ATYDAFALATSIGLRTPNMTLKVGPLAVGVRGPVGLALGVSSVASLTGC
Mb3120c|M.bovis_AF2122/97 -ATYDAFALATSIGLRTPNMTLKVGPLAVGVRGPVGLALGVSSVASLTGC
MMAR_1557|M.marinum_M -ATYDAFALATAIGLGAPGMGLKIGPLAVAVRGPVGLALGVSSVASLTGS
MAV_3337|M.avium_104 -QSYDAIALAALVGAAVPGLGVGTSVVPINPRHPLIVASLAQTAQAAAHG
MSMEG_5732|M.smegmatis_MC2_155 -ADIDAIAAAGLIGAAVPGLGVGTAVVPINPRHPLVISAAAQTAQAAAHG
MAB_1339|M.abscessus_ATCC_1997 -YHYDSITMAAVVGQTVPDVTVGVSVIPINPRHPIEVSAAAQTAQAATHG
Mvan_0261|M.vanbaalenii_PYR-1 PYEPDLLTILAVALREVDTIEVASGVVPIQNQHPMQMAQRALTVSLASGG
Mflv_2453|M.gilvum_PYR-GCK PGYLDAMTTVALLGASTSSIEIGTAVIPVQTRHPLILAQQALTTNAACGG
MLBr_00348|M.leprae_Br4923 -WGSDAYTPLAWWGSSTQRVRLGTSVVQLSARTPTACAMAALTLDHLSGG
TH_1703|M.thermoresistible__bu -YSFDAISQLGYLAARTSTIQLATGVVPIYTRTPALLAMTAAGLDYVSDG
MUL_4782|M.ulcerans_Agy99 -WGSDAPSALGYIAARTERMQLGSGVLQVGTRSPVLVAQTAITLSNLSCG
* : . : : . : : : * : .
Rv3093c|M.tuberculosis_H37Rv RVDLALGASSPAIVAGWHGRPWAHHVPVMRETIECLRSIFTG-ARVEYSG
Mb3120c|M.bovis_AF2122/97 RVDLALGASSPAIVAGWHGRPWAHHVPVMRETIECLRSIFTG-ARVEYSG
MMAR_1557|M.marinum_M RVDIALGASSPAIVAGWHDRPWAHHVPVMRETIECLRSILGG-ARVDYHG
MAV_3337|M.avium_104 RFSLGLGLGAADLERRTFGTEWPNTITRLREHLTILGSVFHS-GAVDFHG
MSMEG_5732|M.smegmatis_MC2_155 NFTLGLGLGARVIEHYAFGIDRTNTVNRLHEYLQVLRGAFER-GDANFRG
MAB_1339|M.abscessus_ATCC_1997 RFQLGLGLGAPVIEGPSYGLHVDKPIRRLREYLITLRQLLDA-GTADFHG
Mvan_0261|M.vanbaalenii_PYR-1 RFILGLGMTHAAVTEGMWGIPWDRPVRRLNEYLDGLLPLLAG-EPANATG
Mflv_2453|M.gilvum_PYR-GCK RFALGLGLSHDWIINGQLGLPYQRPVHTLRDHLDVLAAAFAGPGQVDVDN
MLBr_00348|M.leprae_Br4923 RHILGLGVSGPQVVEGWYGQPFPKPLSRTREYIDIVRQVWAREAPVVSDG
TH_1703|M.thermoresistible__bu RFTLGLGTSGPQVVEGFHGVPFDAPLGRTREVVEICRKVWRRER-LQYNG
MUL_4782|M.ulcerans_Agy99 RFLLGLGASGPRVIEGLHGVAFDRPLARLKETVEIVRQVFAGGK-VTYSG
. :.** : . : .: : .
Rv3093c|M.tuberculosis_H37Rv RHVNSRG-------------FRLRGAAPDTRIALGAFGPGMIRLAAQHAD
Mb3120c|M.bovis_AF2122/97 RHVNSRG-------------FRLRGAAPDTRIALGAFGPGMIRLAAQHAD
MMAR_1557|M.marinum_M RHVASHG-------------FRLRNPQPEARIALGAFGPGMIRLAARHAD
MAV_3337|M.avium_104 SELSAAPSF-----------PVRVPGGTPIPVYVAAMGPKALQVTGELAD
MSMEG_5732|M.smegmatis_MC2_155 AEYSIELQW-----------PVQVAGGTPIPIYVAAMGPKALRITGEYAD
MAB_1339|M.abscessus_ATCC_1997 QTLTVAPQF-----------TTSQPGGENIPVLVAAMAPQALRATGELAD
Mvan_0261|M.vanbaalenii_PYR-1 ETVTTRG-------------ALVIPGAPRPDVYIAALGPQLLRVAGRRTA
Mflv_2453|M.gilvum_PYR-GCK DTFHVHSPV-----------DVADTAP---ALLLAALGPTMLRIAGERAD
MLBr_00348|M.leprae_Br4923 QHYPLPLTGAGATGLGKALKPITHPLRADIPIMLGAEGPKNVALAAEICD
TH_1703|M.thermoresistible__bu RHYHLPLPPDRGTGLGKPLKLINHPVREHIPIFIAALGPKNVQLTAEIAD
MUL_4782|M.ulcerans_Agy99 SEFQIPRRG----GEARPMRLSTRP-EYDIPIYLAALSPAMLRLTGRIAD
: :.* .* : :..
Rv3093c|M.tuberculosis_H37Rv EVVLNLASPFRVGR--VRAAIDSAAAAAG-RAAPRLTVCVPVAVNP----
Mb3120c|M.bovis_AF2122/97 EVVLNLASPFRVGR--VRAAIDSAAAAAG-RAAPRLTVWVPVAVNP----
MMAR_1557|M.marinum_M EVVLNLASPARVAE--VRHAIDSAAAAAAGRAAPRLTVWVPVAVDP----
MAV_3337|M.avium_104 GTLPYLAGPRTIEEFIVPRITKAAAEAGRP--APRIIAAVPVLLSD----
MSMEG_5732|M.smegmatis_MC2_155 GTLPYLAGPRTLSEFIVPTINDAAEAAGRP--QPRVTAMVPVVLSD----
MAB_1339|M.abscessus_ATCC_1997 GTIPLHAGPRALGQEVVPVISAAAERAGRP--RPRVIAGVAVVVTS----
Mvan_0261|M.vanbaalenii_PYR-1 GTCTWMTGPATLRDHVSPALRQAAADAGRPPGSVRVVASLPVAVTD----
Mflv_2453|M.gilvum_PYR-GCK GTVLWMADERAIGEHVVPRIGAAAQGAGRP--APRVVAGVPVALCEP---
MLBr_00348|M.leprae_Br4923 GWLPIFFSP-RMADMYNEWLDEGFARTGARRSREDFEICASAQIVVT---
TH_1703|M.thermoresistible__bu GWQPVFVDPERIDSVWGDALRAGRAKRDP--TLGPLDVMGTPPLAIG---
MUL_4782|M.ulcerans_Agy99 GWLGTSFVPEGAGDAYFTHLDAGLAAAGR--SRADIDFCQGAEVAFASGV
. . :
Rv3093c|M.tuberculosis_H37Rv --GAAAHSQLAAQLAVYLA------PPGYGEMFSALGFDGLVRSARSRA-
Mb3120c|M.bovis_AF2122/97 --GAAAHSQLAAQLAVYLA------PPGYGEMFSALGFDGLVRSARSRA-
MMAR_1557|M.marinum_M --GAAAHAQLAAQLAVYLG------PPGYGEMFSALGFDRLVGAARAGA-
MAV_3337|M.avium_104 -DVEGARAAAAQQLSFYET------IPSYRNVIAREGLSNAV--------
MSMEG_5732|M.smegmatis_MC2_155 -DAETARRTAAEQLAFYAT------IPSYQKVIAREGISDLT--------
MAB_1339|M.abscessus_ATCC_1997 -EPERVRALAIEDMAFYEN------IPSYRKVLDAEGVQHTG--------
Mvan_0261|M.vanbaalenii_PYR-1 -DVEAARKQAAEQFAVYGT------LPSYRAMLDREGYAGPE--------
Mflv_2453|M.gilvum_PYR-GCK ADVDDARAHASEILGHAHL------SPNYVALLEHGDADDVG--------
MLBr_00348|M.leprae_Br4923 EDRAAAFAGIKPFLALYMGGMGAEGTNFHADVYRRMGYAEVVDEVTALFR
TH_1703|M.thermoresistible__bu DDVEDRIAWVKPMLALYLGGMGARDKNFYHNLATRYGFGAEADRIQELYL
MUL_4782|M.ulcerans_Agy99 EELRDMVAARKTELAFSLGGMGSASTNYYNQAYSRQGWSEVAAAVRERWQ
:. : .
Rv3093c|M.tuberculosis_H37Rv --TRRELAVAVPSELLDRVCALGSPDRVAARLRAYADAGADCVAVVPATA
Mb3120c|M.bovis_AF2122/97 --TRRELAVAVPSELLDRVCALGSPDRVAARLRAYADAGADCVAVVPATA
MMAR_1557|M.marinum_M --SRRELAAAIPVELLEQVGALGTAERVAARLRDYEAAGADCLALVPCTA
MAV_3337|M.avium_104 -----------------ELAAIGPEESVLRQVRRYFDAGATDVVLSPLDR
MSMEG_5732|M.smegmatis_MC2_155 -----------------ELAALGSPDQVREKLQSYLDAGATDVVLSPLQV
MAB_1339|M.abscessus_ATCC_1997 -----------------ELAIIGDEQHVATELQRYFDAGATEVFASHTEL
Mvan_0261|M.vanbaalenii_PYR-1 -----------------DAAIIGDEATVRDRLAELAEAGVDEYVGAVFDS
Mflv_2453|M.gilvum_PYR-GCK -----------------DTMAAGDESAVLTRLRAYRDAGVTDLAARVIPL
MLBr_00348|M.leprae_Br4923 SNQKDKAAEIIPNELVDSTMIVGDVDYVCKQIAAWSAAGVTMMMVS---A
TH_1703|M.thermoresistible__bu AGRKEEAAAAVPDDLVRSVSLIGPAGLVAERVAMFAEAGVTTLLVTPLAT
MUL_4782|M.ulcerans_Agy99 RGDREGAARLVTDEMVLATTLIGTEEMVRSRLVAWRDAGVNTVRLYPAGD
* * .: **.
Rv3093c|M.tuberculosis_H37Rv EDP-----GGRVALRALRPGGLYGTAGDNDGRR
Mb3120c|M.bovis_AF2122/97 EDP-----GGRVALRALRPGGLYGTAGDNDGRR
MMAR_1557|M.marinum_M EDP-----AGRATLNALS------RKGES----
MAV_3337|M.avium_104 SAS-----VDREALWRLTAAL------------
MSMEG_5732|M.smegmatis_MC2_155 EQ------NDLEELWAVAASL------------
MAB_1339|M.abscessus_ATCC_1997 GGP-----QDEARTLALLGELSRGN--------
Mvan_0261|M.vanbaalenii_PYR-1 SA------EGRDRTRALLRDMRSGG--------
Mflv_2453|M.gilvum_PYR-GCK GDTPARRHQSRRRTAEFLASVAAGL--------
MLBr_00348|M.leprae_Br4923 SSVEQ--VRDLAGLF------------------
TH_1703|M.thermoresistible__bu DTAEA--VRFIEQLRTMVA--------------
MUL_4782|M.ulcerans_Agy99 TMDAK--LSTLGRAIELVRAVR-----------