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RTATTVELSGGKDGKDTVDFVVEAEKLGLHTCWVAEAWGSDAPSALGYIAARTERMQLGSGVLQVGTRSP VLVAQTAITLSNLSCGRFLLGLGASGPRVIEGLHGVAFDRPLARLKETVEIVRQVFAGGKVTYSGSEFQI PRRGGEARPMRLSTRPEYDIPIYLAALSPAMLRLTGRIADGWLGTSFVPEGAGDAYFTHLDAGLAAAGRS RADIDFCQGAEVAFASGVEELRDMVAARKTELAFSLGGMGSASTNYYNQAYSRQGWSEVAAAVRERWQRG DREGAARLVTDEMVLATTLIGTEEMVRSRLVAWRDAGVNTVRLYPAGDTMDAKLSTLGRAIELVRAVR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_4782 | - | - | 100% (349) | coenzyme F420-dependent oxidoreductase |
| M. ulcerans Agy99 | MUL_4943 | - | 8e-66 | 39.71% (350) | coenzyme F420-dependent oxidoreductase |
| M. ulcerans Agy99 | MUL_4079 | - | 7e-54 | 38.49% (317) | coenzyme F420-dependent oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3550c | - | 2e-53 | 37.42% (326) | coenzyme F420-dependent oxidoreductase |
| M. gilvum PYR-GCK | Mflv_4941 | - | 2e-61 | 40.24% (333) | luciferase family protein |
| M. tuberculosis H37Rv | Rv3520c | - | 2e-53 | 37.42% (326) | coenzyme F420-dependent oxidoreductase |
| M. leprae Br4923 | MLBr_00348 | - | 2e-51 | 36.66% (311) | putative coenzyme F420-dependent oxidoreductase |
| M. abscessus ATCC 19977 | MAB_3748 | - | 8e-60 | 39.27% (331) | putative luciferase-like oxidoreductase |
| M. marinum M | MMAR_0338 | - | 0.0 | 98.58% (352) | coenzyme F420-dependent oxidoreductase |
| M. avium 104 | MAV_0137 | - | 2e-63 | 38.70% (354) | oxidoreductase |
| M. smegmatis MC2 155 | MSMEG_6602 | - | 3e-63 | 38.57% (350) | oxidoreductase |
| M. thermoresistible (build 8) | TH_1703 | - | 3e-58 | 40.12% (339) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_1478 | - | 3e-62 | 40.90% (335) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_0137|M.avium_104 -----MTMRIGLSINYAGG-----FKDVAAEVADLENAGLDIVFVPEAYS
MSMEG_6602|M.smegmatis_MC2_155 -------MKIGLSINYAGG-----FKDIAAEVADLERAGLDIVFVPEAYS
MAB_3748|M.abscessus_ATCC_1997 -------MRIGTTLSYAGG-----FTEVVDELAELEKIGLDIAFVAEAYS
Mflv_4941|M.gilvum_PYR-GCK -------MRTGIFLSYAGG-----FLEAVDEVVECEKLGVDIALVAEAYS
Mvan_1478|M.vanbaalenii_PYR-1 -------MRTGIFLSYAGG-----FLEAVDEVVECEKLGVDIALVAEAYS
TH_1703|M.thermoresistible__bu -------MRIGMQLAYSGG-----FKETAGLVVELEKVGLDLAVVPEAYS
Mb3550c|M.bovis_AF2122/97 -MEAG--MKLGLQLGYWGAQP---PQNHAELVAAAEDAGFDTVFTAEAWG
Rv3520c|M.tuberculosis_H37Rv -MEAG--MKLGLQLGYWGAQP---PQNHAELVAAAEDAGFDTVFTAEAWG
MLBr_00348|M.leprae_Br4923 MVERANAMKLGLQLGYWAAQP---PGNAAELVAAAEGAGFDAVFTGEAWG
MUL_4782|M.ulcerans_Agy99 -------MRTATTVELSGGKD---GKDTVDFVVEAEKLGLHTCWVAEAWG
MMAR_0338|M.marinum_M -------MRTATTVELSGGKDSKDGKDVVDFVVEAEKLGLHTCWVAEAWG
*: . : .. : . :. * *.. . **:.
MAV_0137|M.avium_104 FDAVSALGYLAASTQRVELASGILQLYTRTPTLTAMTAAGLDYVSDGRFT
MSMEG_6602|M.smegmatis_MC2_155 FDAVSGLGYLAARTDRVQLASGILQLYTRTPTLTAMTAAGLDYVSDGRFI
MAB_3748|M.abscessus_ATCC_1997 YDAASQLGYLAAKTSTVKLASGIFQLYTRTPTLLAMTAAGLDYVSGGRFV
Mflv_4941|M.gilvum_PYR-GCK YDAISQLGFLAARTSRIELGTGVVPIYTRTPALMAMTAAGVDYVSDGRFR
Mvan_1478|M.vanbaalenii_PYR-1 YDAISQLGFLAARTSRIELGTGVVPIYTRTPALMAMTAAGLDYVSDGRFR
TH_1703|M.thermoresistible__bu FDAISQLGYLAARTSTIQLATGVVPIYTRTPALLAMTAAGLDYVSDGRFT
Mb3550c|M.bovis_AF2122/97 SDAYTPLAWWGSSTQRVRLGTSVIQLSARTPTACAMAALTLDHLSGGRHI
Rv3520c|M.tuberculosis_H37Rv SDAYTPLAWWGSSTQRVRLGTSVIQLSARTPTACAMAALTLDHLSGGRHI
MLBr_00348|M.leprae_Br4923 SDAYTPLAWWGSSTQRVRLGTSVVQLSARTPTACAMAALTLDHLSGGRHI
MUL_4782|M.ulcerans_Agy99 SDAPSALGYIAARTERMQLGSGVLQVGTRSPVLVAQTAITLSNLSCGRFL
MMAR_0338|M.marinum_M SDAPSALGYIAARTERMQLGSGVLQVGTRSPVLVAQTAITLSNLSCGRFL
** : *.: .: *. :.*.:.:. : :*:*. * :* :. :* **.
MAV_0137|M.avium_104 LGLGASGPQVIEGFHGVPYDAPIGRTREVIEICRQVWRRE-PVQHRGKHY
MSMEG_6602|M.smegmatis_MC2_155 LGLGASGPQVIEGFHGVRYDAPIARTREVVEICRRVWRRE-RLQYEGKHY
MAB_3748|M.abscessus_ATCC_1997 LGIGASGPQVIEGFHGVKYDAPLGRTRETVEICRKVWRRE-RLEFEGKYF
Mflv_4941|M.gilvum_PYR-GCK LGLGTSGPQVIEGFHGLPFDAPLGRTREVVEICRKVWRRE-RVSYDGKYY
Mvan_1478|M.vanbaalenii_PYR-1 LGLGTSGPQVVEGFHGVPFDAPLGRTREVVEICRQVWRRE-RLSYDGKYY
TH_1703|M.thermoresistible__bu LGLGTSGPQVVEGFHGVPFDAPLGRTREVVEICRKVWRRE-RLQYNGRHY
Mb3550c|M.bovis_AF2122/97 LGLGVSGPQVVEGWYGQRFPKPLARTREYIDIVRQVWARESPVTSAGPHY
Rv3520c|M.tuberculosis_H37Rv LGLGVSGPQVVEGWYGQRFPKPLARTREYIDIVRQVWARESPVTSAGPHY
MLBr_00348|M.leprae_Br4923 LGLGVSGPQVVEGWYGQPFPKPLSRTREYIDIVRQVWAREAPVVSDGQHY
MUL_4782|M.ulcerans_Agy99 LGLGASGPRVIEGLHGVAFDRPLARLKETVEIVRQVFAGG-KVTYSGSEF
MMAR_0338|M.marinum_M LGLGASGPQVIEGLHGVAFDRPLARLKETVEIVRQVFAGG-KVTYSGSEF
**:*.***:*:** :* : *:.* :* ::* *:*: : * :
MAV_0137|M.avium_104 TIPLPADRGTGLGKPLKLINSPVRERIPILVAALGPKNVEMAAEIAEGWQ
MSMEG_6602|M.smegmatis_MC2_155 TVPLPADQGTGLGKALKLINQPVRERIPVLLAALGPKNVELAAEIAEGWQ
MAB_3748|M.abscessus_ATCC_1997 TVPLPPEQGTGLGKALKLINHPVRDRIPVLIAALGPKNVALTAEIAEGWQ
Mflv_4941|M.gilvum_PYR-GCK QLPLPAERGTGLGKPLKLINHPVRENIPITIAALGPKNVELTAEIAEGWQ
Mvan_1478|M.vanbaalenii_PYR-1 QLPLPSDKGTGLGKPLKLINHPVRERIPITIAALGPKNVELTAEIAEGWQ
TH_1703|M.thermoresistible__bu HLPLPPDRGTGLGKPLKLINHPVREHIPIFIAALGPKNVQLTAEIADGWQ
Mb3550c|M.bovis_AF2122/97 RLPLTGEGTTGLGKALKPITHPLRADIPIMLGAEGPKNVALAAEICDGWL
Rv3520c|M.tuberculosis_H37Rv RLPLTGEGTTGLGKALKPITHPLRADIPIMLGAEGPKNVALAAEICDGWL
MLBr_00348|M.leprae_Br4923 PLPLTGAGATGLGKALKPITHPLRADIPIMLGAEGPKNVALAAEICDGWL
MUL_4782|M.ulcerans_Agy99 QIPRRG----GEARPMRLSTRPEYD-IPIYLAALSPAMLRLTGRIADGWL
MMAR_0338|M.marinum_M QIPRRG----GEARPMRLSTRPEYD-IPIYLAALSPAMLRLTGRIADGWL
:* * .:.:: . * **: :.* .* : ::..*.:**
MAV_0137|M.avium_104 PIFYLPEKARDVWGESLAAGRAKRAAELG--ELEIYAGPVLAIGENTEPL
MSMEG_6602|M.smegmatis_MC2_155 PIFFLPEKAATVWGDALKAGKTKRDPALG--ELNVYAGPVLAIGDNVEPL
MAB_3748|M.abscessus_ATCC_1997 PIFFLPEKANDVWGAALAEGKAKRDPALG--DLEVYAGPALAIGDDVEAL
Mflv_4941|M.gilvum_PYR-GCK PVFFYPEKADEVWGDALRAGASRRDPALG--PLDVMVSATLAIGDDVDDR
Mvan_1478|M.vanbaalenii_PYR-1 PVFFYPEKADDVWGDALRAGASRRDPALG--PLDTMVSASLAIGDDVDDR
TH_1703|M.thermoresistible__bu PVFVDPERIDSVWGDALRAGRAKRDPTLG--PLDVMGTPPLAIGDDVEDR
Mb3550c|M.bovis_AF2122/97 PIFYSP-RMAGMYNEWLDEGFARPGARRSREDFEICATAQVVITDDRAAA
Rv3520c|M.tuberculosis_H37Rv PIFYSP-RMAGMYNEWLDEGFARPGARRSREDFEICATAQVVITDDRAAA
MLBr_00348|M.leprae_Br4923 PIFFSP-RMADMYNEWLDEGFARTGARRSREDFEICASAQIVVTEDRAAA
MUL_4782|M.ulcerans_Agy99 GTSFVPEGAGDAYFTHLDAGLAAAGRSRA--DIDFCQGAEVAFASGVEEL
MMAR_0338|M.marinum_M GTSFVPEGAGDAYFTHLDAGLAAAGRSRA--DIDFCQGAEVAFASGVEEL
* : * * : . :: . :.. ..
MAV_0137|M.avium_104 REFV---KPHLALYIGGMGAKGKNFYHALATKYGYGPQADRIQELYLAGD
MSMEG_6602|M.smegmatis_MC2_155 REFV---KPHLALYIGGMGAKGKNFYHSLATSYGYGAEADRIQELYLAGE
MAB_3748|M.abscessus_ATCC_1997 YGFV---KPSLALYIGGMGAKGKNFYHNLATAYGFGKEADTIQELYLSGK
Mflv_4941|M.gilvum_PYR-GCK LSWG---KPQLALYIGGMGARGKNFYHNLATRYGFGEVADHIQDLYLAGK
Mvan_1478|M.vanbaalenii_PYR-1 LAWA---KPQLALYIGGMGARGKNFYHNLATRYGFGEVADHIQDLYLAGK
TH_1703|M.thermoresistible__bu IAWV---KPMLALYLGGMGARDKNFYHNLATRYGFGAEADRIQELYLAGR
Mb3550c|M.bovis_AF2122/97 FAGI---KPFLALYMGGMGAEETNFHADVYRRMGYTQVVDEVTKLFRSGR
Rv3520c|M.tuberculosis_H37Rv FAGI---KPFLALYMGGMGAEETNFHADVYRRMGYTQVVDEVTKLFRSGR
MLBr_00348|M.leprae_Br4923 FAGI---KPFLALYMGGMGAEGTNFHADVYRRMGYAEVVDEVTALFRSNQ
MUL_4782|M.ulcerans_Agy99 RDMVAARKTELAFSLGGMGSASTNYYNQAYSRQGWSEVAAAVRERWQRGD
MMAR_0338|M.marinum_M RDMVAARKTELAFSLGGMGSASTNYYNQAYSRQGWSEVAAAVRERWQRGD
*. **: :****: .*:: *: . : : .
MAV_0137|M.avium_104 KDGAAKVVPDDLVRDVNLIGSREFVKERVAAFREAGVTTLNVAPMASTPA
MSMEG_6602|M.smegmatis_MC2_155 KDAAAKAVPDELVRDVNLIGSAGFVRERIAAYREAGVTTLNVVPIGETAA
MAB_3748|M.abscessus_ATCC_1997 KAEATDAVPDELVKNISLIGPKSFVAERVAAFKEAGVTTLNVAPLAADAA
Mflv_4941|M.gilvum_PYR-GCK KAEAIDAVPDELVRQVSLVGPAGFVKERLAAFAEAGVTTLLVHPMGVDAA
Mvan_1478|M.vanbaalenii_PYR-1 KAEAIDAVPDELVRQVSLVGPAGFVKERLAAYAEAGVTTMLVHPLSGDRR
TH_1703|M.thermoresistible__bu KEEAAAAVPDDLVRSVSLIGPAGLVAERVAMFAEAGVTTLLVTPLATDTA
Mb3550c|M.bovis_AF2122/97 KDEAAEIIPDELVDDAVIVGDIDHVRKQMAVWEAAGVTMMVVT------A
Rv3520c|M.tuberculosis_H37Rv KDEAAEIIPDELVDDAVIVGDIDHVRKQMAVWEAAGVTMMVVT------A
MLBr_00348|M.leprae_Br4923 KDKAAEIIPNELVDSTMIVGDVDYVCKQIAAWSAAGVTMMMVS------A
MUL_4782|M.ulcerans_Agy99 REGAARLVTDEMVLATTLIGTEEMVRSRLVAWRDAGVNTVRLYPAGDTMD
MMAR_0338|M.marinum_M REGAARLVTDEMVLATTLIGTEEMVRSRLVAWRDAGVNTVRLYPAGDTMD
: * :.:::* ::* * .::. : ***. : :
MAV_0137|M.avium_104 ERVKLIEALRQLV----
MSMEG_6602|M.smegmatis_MC2_155 DRVRLIEQLRELV----
MAB_3748|M.abscessus_ATCC_1997 GRIKHVEALRELL----
Mflv_4941|M.gilvum_PYR-GCK ERVRFVEQLQGLL----
Mvan_1478|M.vanbaalenii_PYR-1 ETVKFVEELQNLLP---
TH_1703|M.thermoresistible__bu EAVRFIEQLRTMVA---
Mb3550c|M.bovis_AF2122/97 GSAEQVRDLAALV----
Rv3520c|M.tuberculosis_H37Rv GSAEQVRDLAALV----
MLBr_00348|M.leprae_Br4923 SSVEQVRDLAGLF----
MUL_4782|M.ulcerans_Agy99 AKLSTLGRAIELVRAVR
MMAR_0338|M.marinum_M AKLSTLGRAIELVRAVR
: :.