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VTDLEVALPFWLDRPDDEAMEVALAASNAGFDVLWVGEMATYDAFALATAIGLGAPGMGLKIGPLAVAVR GPVGLALGVSSVASLTGSRVDIALGASSPAIVAGWHDRPWAHHVPVMRETIECLRSILGGARVDYHGRHV ASHGFRLRNPQPEARIALGAFGPGMIRLAARHADEVVLNLASPARVAEVRHAIDSAAAAAAGRAAPRLTV WVPVAVDPGAAAHAQLAAQLAVYLGPPGYGEMFSALGFDRLVGAARAGASRRELAAAIPVELLEQVGALG TAERVAARLRDYEAAGADCLALVPCTAEDPAGRATLNALSRKGES
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_1557 | - | - | 100% (325) | oxidoreductase |
| M. marinum M | MMAR_0338 | - | 2e-18 | 27.91% (326) | coenzyme F420-dependent oxidoreductase |
| M. marinum M | MMAR_5005 | - | 2e-16 | 24.92% (329) | coenzyme F420-dependent oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3120c | - | 1e-141 | 78.64% (323) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_4941 | - | 1e-16 | 25.88% (313) | luciferase family protein |
| M. tuberculosis H37Rv | Rv3093c | - | 1e-140 | 78.33% (323) | oxidoreductase |
| M. leprae Br4923 | MLBr_00348 | - | 4e-19 | 24.78% (335) | putative coenzyme F420-dependent oxidoreductase |
| M. abscessus ATCC 19977 | MAB_4166c | - | 9e-17 | 25.39% (323) | putative luciferase-like protein |
| M. avium 104 | MAV_3337 | - | 8e-22 | 26.07% (303) | monooxygenase |
| M. smegmatis MC2 155 | MSMEG_0339 | - | 3e-18 | 24.85% (326) | FMN-dependent monooxygenase |
| M. thermoresistible (build 8) | TH_1703 | - | 1e-16 | 26.09% (322) | oxidoreductase |
| M. ulcerans Agy99 | MUL_4782 | - | 2e-18 | 27.91% (326) | coenzyme F420-dependent oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_4198 | - | 6e-16 | 28.39% (310) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4941|M.gilvum_PYR-GCK -------MRTGIFLSYAGG--FLEAVDEVVECEKLGVDIALVAEAY-SYD
TH_1703|M.thermoresistible__bu -------MRIGMQLAYSGG--FKETAGLVVELEKVGLDLAVVPEAY-SFD
MLBr_00348|M.leprae_Br4923 MVERANAMKLGLQLGYWAAQPPGNAAELVAAAEGAGFDAVFTGEAW-GSD
MSMEG_0339|M.smegmatis_MC2_155 -----------MQLGYWAAQPPSNHAELVAAAEDAGFDTVFTAEAW-GSD
MAB_4166c|M.abscessus_ATCC_199 -------MKFGLQLGYWSASPPENAGELVAAAEEGGFDAVFTAEAW-GSD
MUL_4782|M.ulcerans_Agy99 -------MRTATTVELSGGKDGKDTVDFVVEAEKLGLHTCWVAEAW-GSD
Mb3120c|M.bovis_AF2122/97 --MTDIEVALPFWLDRPD----HEATDVALAAADTGFAALWIGEMA-TYD
Rv3093c|M.tuberculosis_H37Rv --MTDIEVALPFWLDRPD----HEATDVALAAADTGFAALWIGEMA-TYD
MMAR_1557|M.marinum_M --MTDLEVALPFWLDRPD----DEAMEVALAASNAGFDVLWVGEMA-TYD
MAV_3337|M.avium_104 ---MSAGIILMAHPDAAN--LVDDVIAQARRAHELGVGQVWLAQQQ-SYD
Mvan_4198|M.vanbaalenii_PYR-1 ---MRIGLMVGSDRDRPRPDRLDGVITDGTAAEALGFSSFWFPQVPGYLD
*. : *
Mflv_4941|M.gilvum_PYR-GCK AISQLGFLAARTSRIELGTGVVPIYTRTPALMAMTAAGVDYVSDGRFRLG
TH_1703|M.thermoresistible__bu AISQLGYLAARTSTIQLATGVVPIYTRTPALLAMTAAGLDYVSDGRFTLG
MLBr_00348|M.leprae_Br4923 AYTPLAWWGSSTQRVRLGTSVVQLSARTPTACAMAALTLDHLSGGRHILG
MSMEG_0339|M.smegmatis_MC2_155 AFTPLAWWGRETSRLRLGTSVVQMSARTPTACAMASLTLDHLSGGRHILG
MAB_4166c|M.abscessus_ATCC_199 AYTPLAWWGSDTSRIRLGTSVIQLSARTPTACAMAALTLDHLSGGRHILG
MUL_4782|M.ulcerans_Agy99 APSALGYIAARTERMQLGSGVLQVGTRSPVLVAQTAITLSNLSCGRFLLG
Mb3120c|M.bovis_AF2122/97 AFALATSIGLRTPNMTLKVGPLAVGVRGPVGLALGVSSVASLTGCRVDLA
Rv3093c|M.tuberculosis_H37Rv AFALATSIGLRTPNMTLKVGPLAVGVRGPVGLALGVSSVASLTGCRVDLA
MMAR_1557|M.marinum_M AFALATAIGLGAPGMGLKIGPLAVAVRGPVGLALGVSSVASLTGSRVDIA
MAV_3337|M.avium_104 AIALAALVGAAVPGLGVGTSVVPINPRHPLIVASLAQTAQAAAHGRFSLG
Mvan_4198|M.vanbaalenii_PYR-1 AMTALALLGASTTTIELGTAVVPIQTRHPMILAQQGLTTNAACGGRFTLG
* : . . : : . : : * * * * :.
Mflv_4941|M.gilvum_PYR-GCK LGTSGPQVIEGFHGLPFDAPLGRTREVVEICRKVWRRER-VSYDGKYYQL
TH_1703|M.thermoresistible__bu LGTSGPQVVEGFHGVPFDAPLGRTREVVEICRKVWRRER-LQYNGRHYHL
MLBr_00348|M.leprae_Br4923 LGVSGPQVVEGWYGQPFPKPLSRTREYIDIVRQVWAREAPVVSDGQHYPL
MSMEG_0339|M.smegmatis_MC2_155 LGVSGPQVVEGWYGQKFPKPLARTREYVDIIRQVWAREAPVTSDGPHYPL
MAB_4166c|M.abscessus_ATCC_199 LGVSGPQVVEGWYGQPFPKPLARTREYIDIIRQVLAREAPVRSDGPHYPL
MUL_4782|M.ulcerans_Agy99 LGASGPRVIEGLHGVAFDRPLARLKETVEIVRQVFAGGK-VTYSGSEFQI
Mb3120c|M.bovis_AF2122/97 LGASSPAIVAGWHGRPWAHHVPVMRETIECLRSIFTG-ARVEYSGRHVN-
Rv3093c|M.tuberculosis_H37Rv LGASSPAIVAGWHGRPWAHHVPVMRETIECLRSIFTG-ARVEYSGRHVN-
MMAR_1557|M.marinum_M LGASSPAIVAGWHDRPWAHHVPVMRETIECLRSILGG-ARVDYHGRHVA-
MAV_3337|M.avium_104 LGLGAADLERRTFGTEWPNTITRLREHLTILGSVFHS-GAVDFHGSELS-
Mvan_4198|M.vanbaalenii_PYR-1 LGLSHDWIINGQLGIPYQRPVRELRDHLEVLTAAFDGPGQVDVDNDSFR-
** . : . : : :: : : .
Mflv_4941|M.gilvum_PYR-GCK PLPAERGTGLGKPLKLINHPVRENIPITIAALGPKNVELTAEIAEGWQPV
TH_1703|M.thermoresistible__bu PLPPDRGTGLGKPLKLINHPVREHIPIFIAALGPKNVQLTAEIADGWQPV
MLBr_00348|M.leprae_Br4923 PLTGAGATGLGKALKPITHPLRADIPIMLGAEGPKNVALAAEICDGWLPI
MSMEG_0339|M.smegmatis_MC2_155 PLAGAGTTGLGKALKPITHPLRADIPIMLGAEGPRNVALAAEICDGWLPI
MAB_4166c|M.abscessus_ATCC_199 PLTGDKATGLGKPLKPIVHPLRSDIPIFLGAEGPKNVALTAEIADGWLPM
MUL_4782|M.ulcerans_Agy99 PRRG----GEARPMRLSTRP-EYDIPIYLAALSPAMLRLTGRIADGWLGT
Mb3120c|M.bovis_AF2122/97 ----------SRG-FRLRGA-APDTRIALGAFGPGMIRLAAQHADEVVLN
Rv3093c|M.tuberculosis_H37Rv ----------SRG-FRLRGA-APDTRIALGAFGPGMIRLAAQHADEVVLN
MMAR_1557|M.marinum_M ----------SHG-FRLRNP-QPEARIALGAFGPGMIRLAARHADEVVLN
MAV_3337|M.avium_104 ----------AAPSFPVRVPGGTPIPVYVAAMGPKALQVTGELADGTLPY
Mvan_4198|M.vanbaalenii_PYR-1 ----------VHS--PVDVS-DLSPPVLLAALGPTMLRIAGERTDGTILW
. : :.* .* : ::.. :
Mflv_4941|M.gilvum_PYR-GCK FFYPEKADEVWGDALRAGASRRDP--ALGPLDVMVSATLAIG---DDVDD
TH_1703|M.thermoresistible__bu FVDPERIDSVWGDALRAGRAKRDP--TLGPLDVMGTPPLAIG---DDVED
MLBr_00348|M.leprae_Br4923 FFSP-RMADMYNEWLDEGFARTGARRSREDFEICASAQIVVT---EDRAA
MSMEG_0339|M.smegmatis_MC2_155 FYTP-RMADTYNAWLDEGFAKPGARRTRETFEICATANIVIT---EDRAA
MAB_4166c|M.abscessus_ATCC_199 FYAP-RLADMYNEWLDEGFSRPGARRSREDFEIAATAQVIVT---EDRRS
MUL_4782|M.ulcerans_Agy99 SFVPEGAGDAYFTHLDAGLAAAGR--SRADIDFCQGAEVAFASGVEELRD
Mb3120c|M.bovis_AF2122/97 LASPFRVGRVRAAIDSAAAAAG-RAAPRLTVWVPVAVNPG--------AA
Rv3093c|M.tuberculosis_H37Rv LASPFRVGRVRAAIDSAAAAAG-RAAPRLTVCVPVAVNPG--------AA
MMAR_1557|M.marinum_M LASPARVAEVRHAIDSAAAAAAGRAAPRLTVWVPVAVDPG--------AA
MAV_3337|M.avium_104 LAGPRTIEEFIVPRITKAAAEAGRPAPRIIAAVPVLLSD--D-----VEG
Mvan_4198|M.vanbaalenii_PYR-1 MADERAIAEHVAPRITAAAHAAGRPAPRVVAGVPVAVCAPGD-----VDA
. . .
Mflv_4941|M.gilvum_PYR-GCK RLSWGKPQLALYIGGMGARGKNFYHNLATRYGFGEVADHIQDLYLAGKKA
TH_1703|M.thermoresistible__bu RIAWVKPMLALYLGGMGARDKNFYHNLATRYGFGAEADRIQELYLAGRKE
MLBr_00348|M.leprae_Br4923 AFAGIKPFLALYMGGMGAEGTNFHADVYRRMGYAEVVDEVTALFRSNQKD
MSMEG_0339|M.smegmatis_MC2_155 AFAAMKPYLALYMGGMGAEDTNFHADVYRRMGYGEVVDEVTRLLRSRGKE
MAB_4166c|M.abscessus_ATCC_199 VLDQLKPFSALYIGGMGAVELNFHAEVYRRMGYGEVVDEVTELFRTNRKD
MUL_4782|M.ulcerans_Agy99 MVAARKTELAFSLGGMGSASTNYYNQAYSRQGWSEVAAAVRERWQRGDRE
Mb3120c|M.bovis_AF2122/97 AHSQLAAQLAVYLA------PPGYGEMFSALGFDGLVRSARSRA---TRR
Rv3093c|M.tuberculosis_H37Rv AHSQLAAQLAVYLA------PPGYGEMFSALGFDGLVRSARSRA---TRR
MMAR_1557|M.marinum_M AHAQLAAQLAVYLG------PPGYGEMFSALGFDRLVGAARAGA---SRR
MAV_3337|M.avium_104 ARAAAAQQLSFYET------IPSYRNVIAREGLSNAV-------------
Mvan_4198|M.vanbaalenii_PYR-1 AQRYASELLGHAHF------SPNYVALLEHGDAADVG-------------
. : .
Mflv_4941|M.gilvum_PYR-GCK EAIDAVPDELVRQVSLVGPAGFVKERLAAFAEAGVTTLLVHPMGVDAAER
TH_1703|M.thermoresistible__bu EAAAAVPDDLVRSVSLIGPAGLVAERVAMFAEAGVTTLLVTPLATDTAEA
MLBr_00348|M.leprae_Br4923 KAAEIIPNELVDSTMIVGDVDYVCKQIAAWSAAGVTMMMVS------ASS
MSMEG_0339|M.smegmatis_MC2_155 EAAQAIPDEVVDDAAIVGDVAYVREQIKVWEAAGVTTMVVN------ARS
MAB_4166c|M.abscessus_ATCC_199 KAAEAIPDELVLDTTIVGTEAEVREQIKAWEAAGVTMLVVG------CRS
MUL_4782|M.ulcerans_Agy99 GAARLVTDEMVLATTLIGTEEMVRSRLVAWRDAGVNTVRLYPAGDTMDAK
Mb3120c|M.bovis_AF2122/97 ELAVAVPSELLDRVCALGSPDRVAARLRAYADAGADCVAVVP-ATAEDPG
Rv3093c|M.tuberculosis_H37Rv ELAVAVPSELLDRVCALGSPDRVAARLRAYADAGADCVAVVP-ATAEDPG
MMAR_1557|M.marinum_M ELAAAIPVELLEQVGALGTAERVAARLRDYEAAGADCLALVP-CTAEDPA
MAV_3337|M.avium_104 ------------ELAAIGPEESVLRQVRRYFDAGATDVVL-------SPL
Mvan_4198|M.vanbaalenii_PYR-1 ------------DTMAAGDESCVLNRLRAYRDAGVTDLAARIVPLGDDPA
* * :: : **. :
Mflv_4941|M.gilvum_PYR-GCK VRFVEQLQGLL-------------
TH_1703|M.thermoresistible__bu VRFIEQLRTMVA------------
MLBr_00348|M.leprae_Br4923 VEQVRDLAGLF-------------
MSMEG_0339|M.smegmatis_MC2_155 PEHIHQLTSL--------------
MAB_4166c|M.abscessus_ATCC_199 VEHVKQLSALT-------------
MUL_4782|M.ulcerans_Agy99 LSTLGRAIELVRAVR---------
Mb3120c|M.bovis_AF2122/97 GRVALRALRPGGLYGTAGDNDGRR
Rv3093c|M.tuberculosis_H37Rv GRVALRALRPGGLYGTAGDNDGRR
MMAR_1557|M.marinum_M GRATLNALS------RKGES----
MAV_3337|M.avium_104 DRSASVDREALWRLTAAL------
Mvan_4198|M.vanbaalenii_PYR-1 SRRRSRERTAEFLASVVSEF----