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MQISMFGQISGLGGNPIDATIAYLSQLRDEGFARVWISQLPYEPDLLTILAVALREVDTIEVASGVVPIQ NQHPMQMAQRALTVSLASGGRFILGLGMTHAAVTEGMWGIPWDRPVRRLNEYLDGLLPLLAGEPANATGE TVTTRGALVIPGAPRPDVYIAALGPQLLRVAGRRTAGTCTWMTGPATLRDHVSPALRQAAADAGRPPGSV RVVASLPVAVTDDVEAARKQAAEQFAVYGTLPSYRAMLDREGYAGPEDAAIIGDEATVRDRLAELAEAGV DEYVGAVFDSSAEGRDRTRALLRDMRSGG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0261 | - | - | 100% (309) | luciferase family protein |
| M. vanbaalenii PYR-1 | Mvan_4198 | - | 8e-44 | 39.13% (276) | luciferase family protein |
| M. vanbaalenii PYR-1 | Mvan_4259 | - | 3e-41 | 31.51% (311) | luciferase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3120c | - | 3e-18 | 27.96% (304) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_0410 | - | 1e-160 | 91.48% (305) | luciferase family protein |
| M. tuberculosis H37Rv | Rv3093c | - | 2e-18 | 27.96% (304) | oxidoreductase |
| M. leprae Br4923 | MLBr_00348 | - | 2e-11 | 26.87% (268) | putative coenzyme F420-dependent oxidoreductase |
| M. abscessus ATCC 19977 | MAB_1339 | - | 3e-41 | 35.35% (297) | putative monooxygenase (luciferase-like) |
| M. marinum M | MMAR_4796 | - | 2e-38 | 33.10% (284) | oxidoreductase |
| M. avium 104 | MAV_3337 | - | 5e-41 | 33.93% (280) | monooxygenase |
| M. smegmatis MC2 155 | MSMEG_4879 | - | 8e-40 | 32.04% (284) | hypothetical protein MSMEG_4879 |
| M. thermoresistible (build 8) | TH_3430 | - | 1e-115 | 67.30% (315) | PUTATIVE luciferase family protein |
| M. ulcerans Agy99 | MUL_0365 | - | 3e-38 | 32.38% (281) | oxidoreductase |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_0261|M.vanbaalenii_PYR-1 ---------MQISMFGQ--------ISGLGGNPIDATIAYLSQLRDEGFA
Mflv_0410|M.gilvum_PYR-GCK ---------MQISMFGQ--------ISAFGGNAIDATIGYLSQLRDEGFG
TH_3430|M.thermoresistible__bu -VNRPTTHRMGVLMAGMRISLSIVGLTPDGPDPIDSLVRDLTALRDAGFG
MMAR_4796|M.marinum_M -------MRVGVMIGPE---------RGDSGRKVGRMLADIDWAETAGLD
MUL_0365|M.ulcerans_Agy99 -------MRVGVMIGPE---------RGDSGRKVGRMLADIDWAETAGLD
MSMEG_4879|M.smegmatis_MC2_155 -------MRLGVMIGAE---------RGDMTRKVNKLAADIQWAEAAGLD
MAB_1339|M.abscessus_ATCC_1997 -------MKLGVAIGRP-------LSVQNSTNLVDTFIAHARRVAEAGVR
MAV_3337|M.avium_104 -------MSAGIIL----------MAHPDAANLVDDVIAQARRAHELGVG
Mb3120c|M.bovis_AF2122/97 ------MTDIEVALP------------FWLDRPDHEATDVALAAADTGFA
Rv3093c|M.tuberculosis_H37Rv ------MTDIEVALP------------FWLDRPDHEATDVALAAADTGFA
MLBr_00348|M.leprae_Br4923 MVERANAMKLGLQLG------------YWAAQPPGNAAELVAAAEGAGFD
: : *.
Mvan_0261|M.vanbaalenii_PYR-1 RVWISQLPYEPDLLTILAVALREVDTIEVASGVVPIQNQHPMQMAQRALT
Mflv_0410|M.gilvum_PYR-GCK RVWISQLPYEPDLLTVLAVALHEVDTIEVASGVVPIQNQHPMQMAQRALT
TH_3430|M.thermoresistible__bu RVWLAQLPFDIDLPTVLGIALRAVDGIEVGSGVIPIQPQHPMQLAQRALT
MMAR_4796|M.marinum_M SAWIPQIPNDFDALVAVTLMGTRSSRIELGTAVVPLQTQHPIALARQALS
MUL_0365|M.ulcerans_Agy99 SAWIPQIPNDFDALVAVTLMGTRSSRIELGTAVVPLQTQHPIALARQALS
MSMEG_4879|M.smegmatis_MC2_155 SAWMPQVPDDFDCLSMVALMAAHTSTIELGTAVVPLQAQHPVALARQALS
MAB_1339|M.abscessus_ATCC_1997 TLWLGQM-YHYDSITMAAVVGQTVPDVTVGVSVIPINPRHPIEVSAAAQT
MAV_3337|M.avium_104 QVWLAQQ-QSYDAIALAALVGAAVPGLGVGTSVVPINPRHPLIVASLAQT
Mb3120c|M.bovis_AF2122/97 ALWIGEM-ATYDAFALATSIGLRTPNMTLKVGPLAVGVRGPVGLALGVSS
Rv3093c|M.tuberculosis_H37Rv ALWIGEM-ATYDAFALATSIGLRTPNMTLKVGPLAVGVRGPVGLALGVSS
MLBr_00348|M.leprae_Br4923 AVFTGEA-WGSDAYTPLAWWGSSTQRVRLGTSVVQLSARTPTACAMAALT
: : * : : . : : : * : . :
Mvan_0261|M.vanbaalenii_PYR-1 VSLASGGRFILGLGMTHAAVTEGMWGIPWDRPVRRLNEYLDGLLPLLAG-
Mflv_0410|M.gilvum_PYR-GCK VSLASNGRFILGLGMTHAAVTEGMWGIPWDKPVRRLNEYLDGLLPLLAG-
TH_3430|M.thermoresistible__bu LSLISGGRFLLGIGMSHRMVAEGMWGVSWDRPVRQMREYLDGLQPLLAG-
MMAR_4796|M.marinum_M VHAATGGRLVLGVGPSHHWIVDDMLGLPYQRPAAYTRDYLEVLAAALANP
MUL_0365|M.ulcerans_Agy99 VHAATGGRLVLGVGPSHHWIVDDMLGLPYQRPAAYTRDYLEVLAAALANP
MSMEG_4879|M.smegmatis_MC2_155 VHAIAEGRLALGVGPSHHWIIRDMLGLPYDKPAAYTRDYLEVLNASLAGP
MAB_1339|M.abscessus_ATCC_1997 AQAATHGRFQLGLGLGAPVIEGPSYGLHVDKPIRRLREYLITLRQLLDA-
MAV_3337|M.avium_104 AQAAAHGRFSLGLGLGAADLERRTFGTEWPNTITRLREHLTILGSVFHS-
Mb3120c|M.bovis_AF2122/97 VASLTGCRVDLALGASSPAIVAGWHGRPWAHHVPVMRETIECLRSIFTG-
Rv3093c|M.tuberculosis_H37Rv VASLTGCRVDLALGASSPAIVAGWHGRPWAHHVPVMRETIECLRSIFTG-
MLBr_00348|M.leprae_Br4923 LDHLSGGRHILGLGVSGPQVVEGWYGQPFPKPLSRTREYIDIVRQVWARE
: * *.:* : * . .: : :
Mvan_0261|M.vanbaalenii_PYR-1 EPANATGET----VTTRGALVIPG---------APRPDVYIAALGPQLLR
Mflv_0410|M.gilvum_PYR-GCK EPANATGET----VTTRGALMIPG---------APRPDVYIAALGPQLLR
TH_3430|M.thermoresistible__bu RPADVTGEF----WSTRGALRLAGGGT-----SPPEPPVYLAALGPQMLR
MMAR_4796|M.marinum_M GPVDVENDS----FRVHNPLDLAA---------VAPLPVLVAALGPVMLT
MUL_0365|M.ulcerans_Agy99 GPVDVENDS----FRVHNPLDLAA---------VAPLPVLVAALGPVMLT
MSMEG_4879|M.smegmatis_MC2_155 GPVDVENDT----FTVHNPTALAA---------ETPLPVLVAALGPVMLQ
MAB_1339|M.abscessus_ATCC_1997 GTADFHGQT----LTVAPQFTTSQPG-------GENIPVLVAAMAPQALR
MAV_3337|M.avium_104 GAVDFHGSE----LSAAPSFPVRVPG-------GTPIPVYVAAMGPKALQ
Mb3120c|M.bovis_AF2122/97 ARVEYSGRH----VNSR-GFRLRG--------AAPDTRIALGAFGPGMIR
Rv3093c|M.tuberculosis_H37Rv ARVEYSGRH----VNSR-GFRLRG--------AAPDTRIALGAFGPGMIR
MLBr_00348|M.leprae_Br4923 APVVSDGQHYPLPLTGAGATGLGKALKPITHPLRADIPIMLGAEGPKNVA
. . : :.* .* :
Mvan_0261|M.vanbaalenii_PYR-1 VAGRRTAGTCTWMTGPATLRDHVSPALR-QAAADAGRPPGSVRVVASLPV
Mflv_0410|M.gilvum_PYR-GCK LAGRRTQGTCTWMTGPATLRDHVSPTLR-QAAADAGRPDGSVRVVASLPV
TH_3430|M.thermoresistible__bu LAGRRTAGTLTWMTGPKTLAGHIVPTLR-QAAADAGRSGSDVRVVASLPV
MMAR_4796|M.marinum_M LAGERADGTVLWMADERAVAEHVVPRIS-KAADNAGRPAPRIVAGIPVCL
MUL_0365|M.ulcerans_Agy99 LAGERADGTVLWMADERAVAEHVVPRIS-KAADNAGRPVPRIVAGIPVCL
MSMEG_4879|M.smegmatis_MC2_155 IAGELADGTVLWMADERAIGDHIAPRIN-KAADNAGRPAPRIVAGIPVCL
MAB_1339|M.abscessus_ATCC_1997 ATGELADGTIPLHAGPRALGQEVVPVIS-AAAERAGRPRPRVIAGVAVVV
MAV_3337|M.avium_104 VTGELADGTLPYLAGPRTIEEFIVPRIT-KAAAEAGRPAPRIIAAVPVLL
Mb3120c|M.bovis_AF2122/97 LAAQHADEVVLNLASPFRVG-RVRAAID-SAAAAAGRAAPRLTVWVPVAV
Rv3093c|M.tuberculosis_H37Rv LAAQHADEVVLNLASPFRVG-RVRAAID-SAAAAAGRAAPRLTVCVPVAV
MLBr_00348|M.leprae_Br4923 LAAEICDGWLPIFFSPRMADMYNEWLDEGFARTGARRSREDFEICASAQI
:.. . * * *. . . :
Mvan_0261|M.vanbaalenii_PYR-1 AVTDDVEAARKQAAEQFAVYGT------LPSYRAMLDREGYAGPE-----
Mflv_0410|M.gilvum_PYR-GCK AVTDDVDELRKQAADQFAMYGT------LPSYRAMLDREGYAGPE-----
TH_3430|M.thermoresistible__bu SVTDDVEGARAQAVEQFAVYGT------LPSYRAMLDREGYVNPE-----
MMAR_4796|M.marinum_M CGSSEVEVARDRANRILGEAEV------SPNYQRLLGYGDAKDVG-----
MUL_0365|M.ulcerans_Agy99 CGSSEVEVARDRANRILGEAEV------SPNYQRLLGHGDAKDVG-----
MSMEG_4879|M.smegmatis_MC2_155 CANSEIDTAKERANRILAEAET------SPNYQRLLDRGDARNVG-----
MAB_1339|M.abscessus_ATCC_1997 T--SEPERVRALAIEDMAFYEN------IPSYRKVLDAEGVQHTG-----
MAV_3337|M.avium_104 S--DDVEGARAAAAQQLSFYET------IPSYRNVIAREGLSNAV-----
Mb3120c|M.bovis_AF2122/97 N---PGAAAHSQLAAQLAVYLA------PPGYGEMFSALGFDGLVRSARS
Rv3093c|M.tuberculosis_H37Rv N---PGAAAHSQLAAQLAVYLA------PPGYGEMFSALGFDGLVRSARS
MLBr_00348|M.leprae_Br4923 VVTEDRAAAFAGIKPFLALYMGGMGAEGTNFHADVYRRMGYAEVVDEVT-
:. : : .
Mvan_0261|M.vanbaalenii_PYR-1 -----------------DAAIIGDEATVRDRLA------ELAEAGVDEYV
Mflv_0410|M.gilvum_PYR-GCK -----------------DAAIIGDEATVRDQIA------ELGAAGVDEYV
TH_3430|M.thermoresistible__bu -----------------DAAIIGDEQTVSQRLD------ELAAAGVDEFT
MMAR_4796|M.marinum_M -----------------DICAAGDEDAILARFR------RFAEAGVTDLS
MUL_0365|M.ulcerans_Agy99 -----------------DICAAGDEDAILARFR------RFAEAGVTDLS
MSMEG_4879|M.smegmatis_MC2_155 -----------------DLCAAGDEDAILARFK------RFADAGVTDLS
MAB_1339|M.abscessus_ATCC_1997 -----------------ELAIIGDEQHVATELQ------RYFDAGATEVF
MAV_3337|M.avium_104 -----------------ELAAIGPEESVLRQVR------RYFDAGATDVV
Mb3120c|M.bovis_AF2122/97 RATRRELAVAVPSELLDRVCALGSPDRVAARLR------AYADAGADCVA
Rv3093c|M.tuberculosis_H37Rv RATRRELAVAVPSELLDRVCALGSPDRVAARLR------AYADAGADCVA
MLBr_00348|M.leprae_Br4923 -----------------ALFRSNQKDKAAEIIPNELVDSTMIVGDVDYVC
. . ...
Mvan_0261|M.vanbaalenii_PYR-1 GAVFDSSAE------GRDRTRALLRDMRSGG---
Mflv_0410|M.gilvum_PYR-GCK GAVFDSSVE------GRDRTRALLRELG------
TH_3430|M.thermoresistible__bu AAVFDADPE------IRARTRALLVSRQTG----
MMAR_4796|M.marinum_M VRLLPIGDNREELVASKRRTRDMIATLATEVR--
MUL_0365|M.ulcerans_Agy99 VRLLPIGDNREELVASKRRTRDMIATLATEVR--
MSMEG_4879|M.smegmatis_MC2_155 VRLLPIGDNRDELIASKYRTREVIAELAKAVR--
MAB_1339|M.abscessus_ATCC_1997 ASHTELGGP-----QDEARTLALLGELSRGN---
MAV_3337|M.avium_104 LSPLDRSAS-----VDREALWRLTAAL-------
Mb3120c|M.bovis_AF2122/97 VVPATAEDPGGRVALRALRPGGLYGTAGDNDGRR
Rv3093c|M.tuberculosis_H37Rv VVPATAEDPGGRVALRALRPGGLYGTAGDNDGRR
MLBr_00348|M.leprae_Br4923 KQIAAWSAAGVTMMMVSASSVEQVRDLAGLF---