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MSAGIILMAHPDAANLVDDVIAQARRAHELGVGQVWLAQQQSYDAIALAALVGAAVPGLGVGTSVVPINP RHPLIVASLAQTAQAAAHGRFSLGLGLGAADLERRTFGTEWPNTITRLREHLTILGSVFHSGAVDFHGSE LSAAPSFPVRVPGGTPIPVYVAAMGPKALQVTGELADGTLPYLAGPRTIEEFIVPRITKAAAEAGRPAPR IIAAVPVLLSDDVEGARAAAAQQLSFYETIPSYRNVIAREGLSNAVELAAIGPEESVLRQVRRYFDAGAT DVVLSPLDRSASVDREALWRLTAAL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_3337 | - | - | 100% (305) | monooxygenase |
| M. avium 104 | MAV_0923 | - | 2e-44 | 38.38% (284) | hypothetical protein MAV_0923 |
| M. avium 104 | MAV_2121 | - | 2e-20 | 30.60% (232) | hypothetical protein MAV_2121 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3120c | - | 3e-20 | 25.84% (298) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_2453 | - | 4e-43 | 39.07% (279) | luciferase family protein |
| M. tuberculosis H37Rv | Rv3093c | - | 1e-20 | 25.84% (298) | oxidoreductase |
| M. leprae Br4923 | MLBr_00348 | - | 2e-14 | 25.22% (226) | putative coenzyme F420-dependent oxidoreductase |
| M. abscessus ATCC 19977 | MAB_1339 | - | 9e-78 | 52.92% (274) | putative monooxygenase (luciferase-like) |
| M. marinum M | MMAR_4796 | - | 4e-38 | 33.45% (275) | oxidoreductase |
| M. smegmatis MC2 155 | MSMEG_5732 | - | 1e-104 | 61.31% (305) | monooxygenase |
| M. thermoresistible (build 8) | TH_3430 | - | 9e-45 | 34.03% (288) | PUTATIVE luciferase family protein |
| M. ulcerans Agy99 | MUL_0365 | - | 5e-38 | 33.09% (275) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_4198 | - | 2e-42 | 36.99% (292) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_3337|M.avium_104 -------MSAGIIL---MAHPD-------AANLVDDVIAQARRAHELGVG
MSMEG_5732|M.smegmatis_MC2_155 -----MIMPTGVML---RINPS-------AANAIDGLIADARRAHDIGVK
MAB_1339|M.abscessus_ATCC_1997 -------MKLGVAIGRPLSVQN-------STNLVDTFIAHARRVAEAGVR
Mflv_2453|M.gilvum_PYR-GCK -------MRIGLMVGSDRE--------RARPDRLAGLIEDGIAAETAGFN
Mvan_4198|M.vanbaalenii_PYR-1 -------MRIGLMVGSDRD--------RPRPDRLDGVITDGTAAEALGFS
MMAR_4796|M.marinum_M -------MRVGVMIGPERG--------DSG-RKVGRMLADIDWAETAGLD
MUL_0365|M.ulcerans_Agy99 -------MRVGVMIGPERG--------DSG-RKVGRMLADIDWAETAGLD
TH_3430|M.thermoresistible__bu -VNRPTTHRMGVLMAGMRISLSIVGLTPDGPDPIDSLVRDLTALRDAGFG
Mb3120c|M.bovis_AF2122/97 ------MTDIEVALPFWLD------------RPDHEATDVALAAADTGFA
Rv3093c|M.tuberculosis_H37Rv ------MTDIEVALPFWLD------------RPDHEATDVALAAADTGFA
MLBr_00348|M.leprae_Br4923 MVERANAMKLGLQLGYWAA------------QPPGNAAELVAAAEGAGFD
: : *.
MAV_3337|M.avium_104 QVWLAQQ-QSYDAIALAALVGAAVPGLGVGTSVVPINPRHPLIVASLAQT
MSMEG_5732|M.smegmatis_MC2_155 QIWLAQQ-ADIDAIAAAGLIGAAVPGLGVGTAVVPINPRHPLVISAAAQT
MAB_1339|M.abscessus_ATCC_1997 TLWLGQM-YHYDSITMAAVVGQTVPDVTVGVSVIPINPRHPIEVSAAAQT
Mflv_2453|M.gilvum_PYR-GCK SFWFPQVPGYLDAMTTVALLGASTSSIEIGTAVIPVQTRHPLILAQQALT
Mvan_4198|M.vanbaalenii_PYR-1 SFWFPQVPGYLDAMTALALLGASTTTIELGTAVVPIQTRHPMILAQQGLT
MMAR_4796|M.marinum_M SAWIPQIPNDFDALVAVTLMGTRSSRIELGTAVVPLQTQHPIALARQALS
MUL_0365|M.ulcerans_Agy99 SAWIPQIPNDFDALVAVTLMGTRSSRIELGTAVVPLQTQHPIALARQALS
TH_3430|M.thermoresistible__bu RVWLAQLPFDIDLPTVLGIALRAVDGIEVGSGVIPIQPQHPMQLAQRALT
Mb3120c|M.bovis_AF2122/97 ALWIGEM-ATYDAFALATSIGLRTPNMTLKVGPLAVGVRGPVGLALGVSS
Rv3093c|M.tuberculosis_H37Rv ALWIGEM-ATYDAFALATSIGLRTPNMTLKVGPLAVGVRGPVGLALGVSS
MLBr_00348|M.leprae_Br4923 AVFTGEA-WGSDAYTPLAWWGSSTQRVRLGTSVVQLSARTPTACAMAALT
: : * . : : . : : : * : :
MAV_3337|M.avium_104 AQAAAHGRFSLGLGLGAADLERRTFGTEWPNTITRLREHLTILGSVFHS-
MSMEG_5732|M.smegmatis_MC2_155 AQAAAHGNFTLGLGLGARVIEHYAFGIDRTNTVNRLHEYLQVLRGAFER-
MAB_1339|M.abscessus_ATCC_1997 AQAATHGRFQLGLGLGAPVIEGPSYGLHVDKPIRRLREYLITLRQLLDA-
Mflv_2453|M.gilvum_PYR-GCK TNAACGGRFALGLGLSHDWIINGQLGLPYQRPVHTLRDHLDVLAAAFAGP
Mvan_4198|M.vanbaalenii_PYR-1 TNAACGGRFTLGLGLSHDWIINGQLGIPYQRPVRELRDHLEVLTAAFDGP
MMAR_4796|M.marinum_M VHAATGGRLVLGVGPSHHWIVDDMLGLPYQRPAAYTRDYLEVLAAALANP
MUL_0365|M.ulcerans_Agy99 VHAATGGRLVLGVGPSHHWIVDDMLGLPYQRPAAYTRDYLEVLAAALANP
TH_3430|M.thermoresistible__bu LSLISGGRFLLGIGMSHRMVAEGMWGVSWDRPVRQMREYLDGLQPLLAG-
Mb3120c|M.bovis_AF2122/97 VASLTGCRVDLALGASSPAIVAGWHGRPWAHHVPVMRETIECLRSIFTG-
Rv3093c|M.tuberculosis_H37Rv VASLTGCRVDLALGASSPAIVAGWHGRPWAHHVPVMRETIECLRSIFTG-
MLBr_00348|M.leprae_Br4923 LDHLSGGRHILGLGVSGPQVVEGWYGQPFPKPLSRTREYIDIVRQVWARE
. *.:* . : * . :: : :
MAV_3337|M.avium_104 GAVDFHGSELSAAPSFPVRVPGGTP-----------IPVYVAAMGPKALQ
MSMEG_5732|M.smegmatis_MC2_155 GDANFRGAEYSIELQWPVQVAGGTP-----------IPIYVAAMGPKALR
MAB_1339|M.abscessus_ATCC_1997 GTADFHGQTLTVAPQFTTSQPGGEN-----------IPVLVAAMAPQALR
Mflv_2453|M.gilvum_PYR-GCK GQVDVDNDTFHVHSPVDVADTAP--------------ALLLAALGPTMLR
Mvan_4198|M.vanbaalenii_PYR-1 GQVDVDNDSFRVHSPVDVSDLSP--------------PVLLAALGPTMLR
MMAR_4796|M.marinum_M GPVDVENDSFRVHNPLDLAAVAPL-------------PVLVAALGPVMLT
MUL_0365|M.ulcerans_Agy99 GPVDVENDSFRVHNPLDLAAVAPL-------------PVLVAALGPVMLT
TH_3430|M.thermoresistible__bu RPADVTGEFWSTRGALRLAGGGTSPPE---------PPVYLAALGPQMLR
Mb3120c|M.bovis_AF2122/97 ARVEYSGRHVNSR-GFRLRGAAPDT------------RIALGAFGPGMIR
Rv3093c|M.tuberculosis_H37Rv ARVEYSGRHVNSR-GFRLRGAAPDT------------RIALGAFGPGMIR
MLBr_00348|M.leprae_Br4923 APVVSDGQHYPLPLTGAGATGLGKALKPITHPLRADIPIMLGAEGPKNVA
. . : :.* .* :
MAV_3337|M.avium_104 VTGELADGTLPYLAGPRTIEEF---IVPRITKAAAEAGRPAPRIIAAVPV
MSMEG_5732|M.smegmatis_MC2_155 ITGEYADGTLPYLAGPRTLSEF---IVPTINDAAEAAGRPQPRVTAMVPV
MAB_1339|M.abscessus_ATCC_1997 ATGELADGTIPLHAGPRALGQE---VVPVISAAAERAGRPRPRVIAGVAV
Mflv_2453|M.gilvum_PYR-GCK IAGERADGTVLWMADERAIGEH---VVPRIGAAAQGAGRPAPRVVAGVPV
Mvan_4198|M.vanbaalenii_PYR-1 IAGERTDGTILWMADERAIAEH---VAPRITAAAHAAGRPAPRVVAGVPV
MMAR_4796|M.marinum_M LAGERADGTVLWMADERAVAEH---VVPRISKAADNAGRPAPRIVAGIPV
MUL_0365|M.ulcerans_Agy99 LAGERADGTVLWMADERAVAEH---VVPRISKAADNAGRPVPRIVAGIPV
TH_3430|M.thermoresistible__bu LAGRRTAGTLTWMTGPKTLAGH---IVPTLRQAAADAGRSGSDVRVVASL
Mb3120c|M.bovis_AF2122/97 LAAQHADEVVLNLASPFRVGR----VRAAIDSAAAAAGRAAPRLTVWVPV
Rv3093c|M.tuberculosis_H37Rv LAAQHADEVVLNLASPFRVGR----VRAAIDSAAAAAGRAAPRLTVCVPV
MLBr_00348|M.leprae_Br4923 LAAEICDGWLPIFFSPRMADMYNEWLDEGFARTGARRSREDFEICASAQI
:.. : . : : :. .* : . :
MAV_3337|M.avium_104 LLS----------------------DDVEGARAAAAQQLSFYETIPSYRN
MSMEG_5732|M.smegmatis_MC2_155 VLS----------------------DDAETARRTAAEQLAFYATIPSYQK
MAB_1339|M.abscessus_ATCC_1997 VVT----------------------SEPERVRALAIEDMAFYENIPSYRK
Mflv_2453|M.gilvum_PYR-GCK ALCEP--------------------ADVDDARAHASEILGHAHLSPNYVA
Mvan_4198|M.vanbaalenii_PYR-1 AVCAP--------------------GDVDAAQRYASELLGHAHFSPNYVA
MMAR_4796|M.marinum_M CLCGS--------------------SEVEVARDRANRILGEAEVSPNYQR
MUL_0365|M.ulcerans_Agy99 CLCGS--------------------SEVEVARDRANRILGEAEVSPNYQR
TH_3430|M.thermoresistible__bu PVSVT--------------------DDVEGARAQAVEQFAVYGTLPSYRA
Mb3120c|M.bovis_AF2122/97 AVN-----------------------PGAAAHSQLAAQLAVYLAPPGYGE
Rv3093c|M.tuberculosis_H37Rv AVN-----------------------PGAAAHSQLAAQLAVYLAPPGYGE
MLBr_00348|M.leprae_Br4923 VVTEDRAAAFAGIKPFLALYMGGMGAEGTNFHADVYRRMGYAEVVDEVTA
: : :.
MAV_3337|M.avium_104 VIAREGLSNAV----------------------ELAAIGPEESVLRQVRR
MSMEG_5732|M.smegmatis_MC2_155 VIAREGISDLT----------------------ELAALGSPDQVREKLQS
MAB_1339|M.abscessus_ATCC_1997 VLDAEGVQHTG----------------------ELAIIGDEQHVATELQR
Mflv_2453|M.gilvum_PYR-GCK LLEHGDADDVG----------------------DTMAAGDESAVLTRLRA
Mvan_4198|M.vanbaalenii_PYR-1 LLEHGDAADVG----------------------DTMAAGDESCVLNRLRA
MMAR_4796|M.marinum_M LLGYGDAKDVG----------------------DICAAGDEDAILARFRR
MUL_0365|M.ulcerans_Agy99 LLGHGDAKDVG----------------------DICAAGDEDAILARFRR
TH_3430|M.thermoresistible__bu MLDREGYVNPE----------------------DAAIIGDEQTVSQRLDE
Mb3120c|M.bovis_AF2122/97 MFSALGFDGLVRSARSRATRRELAVAVPSELLDRVCALGSPDRVAARLRA
Rv3093c|M.tuberculosis_H37Rv MFSALGFDGLVRSARSRATRRELAVAVPSELLDRVCALGSPDRVAARLRA
MLBr_00348|M.leprae_Br4923 LFRSNQKDKAAEIIPN-------------ELVDSTMIVGDVDYVCKQIAA
:: * . : ..
MAV_3337|M.avium_104 YFDAGATDVVLSPLDRSAS-----VDREALWRLTAAL-------
MSMEG_5732|M.smegmatis_MC2_155 YLDAGATDVVLSPLQVEQ------NDLEELWAVAASL-------
MAB_1339|M.abscessus_ATCC_1997 YFDAGATEVFASHTELGGP-----QDEARTLALLGELSRGN---
Mflv_2453|M.gilvum_PYR-GCK YRDAGVTDLAARVIPLGDTPARRHQSRRRTAEFLASVAAGL---
Mvan_4198|M.vanbaalenii_PYR-1 YRDAGVTDLAARIVPLGDDPASRRRSRERTAEFLASVVSEF---
MMAR_4796|M.marinum_M FAEAGVTDLSVRLLPIGDNREELVASKRRTRDMIATLATEVR--
MUL_0365|M.ulcerans_Agy99 FAEAGVTDLSVRLLPIGDNREELVASKRRTRDMIATLATEVR--
TH_3430|M.thermoresistible__bu LAAAGVDEFTAAVFDADP------EIRARTRALLVSRQTG----
Mb3120c|M.bovis_AF2122/97 YADAGADCVAVVPATAEDPGGRVALRALRPGGLYGTAGDNDGRR
Rv3093c|M.tuberculosis_H37Rv YADAGADCVAVVPATAEDPGGRVALRALRPGGLYGTAGDNDGRR
MLBr_00348|M.leprae_Br4923 WSAAGVTMMMVSAS-----------SVEQVRDLAGLF-------
**. . .