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VKLGVAIGRPLSVQNSTNLVDTFIAHARRVAEAGVRTLWLGQMYHYDSITMAAVVGQTVPDVTVGVSVIP INPRHPIEVSAAAQTAQAATHGRFQLGLGLGAPVIEGPSYGLHVDKPIRRLREYLITLRQLLDAGTADFH GQTLTVAPQFTTSQPGGENIPVLVAAMAPQALRATGELADGTIPLHAGPRALGQEVVPVISAAAERAGRP RPRVIAGVAVVVTSEPERVRALAIEDMAFYENIPSYRKVLDAEGVQHTGELAIIGDEQHVATELQRYFDA GATEVFASHTELGGPQDEARTLALLGELSRGN
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. abscessus ATCC 19977 | MAB_1339 | - | - | 100% (312) | putative monooxygenase (luciferase-like) |
M. abscessus ATCC 19977 | MAB_2053 | - | 1e-14 | 26.32% (247) | luciferase-like |
M. abscessus ATCC 19977 | MAB_4166c | - | 5e-14 | 28.30% (212) | putative luciferase-like protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3120c | - | 2e-16 | 25.18% (278) | oxidoreductase |
M. gilvum PYR-GCK | Mflv_0410 | - | 1e-40 | 35.91% (298) | luciferase family protein |
M. tuberculosis H37Rv | Rv3093c | - | 2e-16 | 25.18% (278) | oxidoreductase |
M. leprae Br4923 | MLBr_00348 | - | 2e-13 | 23.51% (319) | putative coenzyme F420-dependent oxidoreductase |
M. marinum M | MMAR_4796 | - | 4e-33 | 30.79% (302) | oxidoreductase |
M. avium 104 | MAV_3337 | - | 9e-78 | 52.92% (274) | monooxygenase |
M. smegmatis MC2 155 | MSMEG_5732 | - | 2e-71 | 49.64% (274) | monooxygenase |
M. thermoresistible (build 8) | TH_3430 | - | 7e-42 | 35.40% (291) | PUTATIVE luciferase family protein |
M. ulcerans Agy99 | MUL_0365 | - | 5e-33 | 30.79% (302) | oxidoreductase |
M. vanbaalenii PYR-1 | Mvan_0261 | - | 4e-41 | 35.35% (297) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment MAV_3337|M.avium_104 -------MSAGIIL----------MAHPDAANLVDDVIAQARRAHELGVG MSMEG_5732|M.smegmatis_MC2_155 -----MIMPTGVML----------RINPSAANAIDGLIADARRAHDIGVK MAB_1339|M.abscessus_ATCC_1997 -------MKLGVAIGRP-------LSVQNSTNLVDTFIAHARRVAEAGVR Mflv_0410|M.gilvum_PYR-GCK ---------MQISMFGQ--------ISAFGGNAIDATIGYLSQLRDEGFG Mvan_0261|M.vanbaalenii_PYR-1 ---------MQISMFGQ--------ISGLGGNPIDATIAYLSQLRDEGFA TH_3430|M.thermoresistible__bu -VNRPTTHRMGVLMAGMRISLSIVGLTPDGPDPIDSLVRDLTALRDAGFG MMAR_4796|M.marinum_M -------MRVGVMIGPE---------RGDSGRKVGRMLADIDWAETAGLD MUL_0365|M.ulcerans_Agy99 -------MRVGVMIGPE---------RGDSGRKVGRMLADIDWAETAGLD Mb3120c|M.bovis_AF2122/97 ------MTDIEVALP------------FWLDRPDHEATDVALAAADTGFA Rv3093c|M.tuberculosis_H37Rv ------MTDIEVALP------------FWLDRPDHEATDVALAAADTGFA MLBr_00348|M.leprae_Br4923 MVERANAMKLGLQLG------------YWAAQPPGNAAELVAAAEGAGFD : : *. MAV_3337|M.avium_104 QVWLAQQ-QSYDAIALAALVGAAVPGLGVGTSVVPINPRHPLIVASLAQT MSMEG_5732|M.smegmatis_MC2_155 QIWLAQQ-ADIDAIAAAGLIGAAVPGLGVGTAVVPINPRHPLVISAAAQT MAB_1339|M.abscessus_ATCC_1997 TLWLGQM-YHYDSITMAAVVGQTVPDVTVGVSVIPINPRHPIEVSAAAQT Mflv_0410|M.gilvum_PYR-GCK RVWISQLPYEPDLLTVLAVALHEVDTIEVASGVVPIQNQHPMQMAQRALT Mvan_0261|M.vanbaalenii_PYR-1 RVWISQLPYEPDLLTILAVALREVDTIEVASGVVPIQNQHPMQMAQRALT TH_3430|M.thermoresistible__bu RVWLAQLPFDIDLPTVLGIALRAVDGIEVGSGVIPIQPQHPMQLAQRALT MMAR_4796|M.marinum_M SAWIPQIPNDFDALVAVTLMGTRSSRIELGTAVVPLQTQHPIALARQALS MUL_0365|M.ulcerans_Agy99 SAWIPQIPNDFDALVAVTLMGTRSSRIELGTAVVPLQTQHPIALARQALS Mb3120c|M.bovis_AF2122/97 ALWIGEM-ATYDAFALATSIGLRTPNMTLKVGPLAVGVRGPVGLALGVSS Rv3093c|M.tuberculosis_H37Rv ALWIGEM-ATYDAFALATSIGLRTPNMTLKVGPLAVGVRGPVGLALGVSS MLBr_00348|M.leprae_Br4923 AVFTGEA-WGSDAYTPLAWWGSSTQRVRLGTSVVQLSARTPTACAMAALT : : * . : : . : : : * : . : MAV_3337|M.avium_104 AQAAAHGRFSLGLGLGAADLERRTFGTEWPNTITRLREHLTILGSVFHS- MSMEG_5732|M.smegmatis_MC2_155 AQAAAHGNFTLGLGLGARVIEHYAFGIDRTNTVNRLHEYLQVLRGAFER- MAB_1339|M.abscessus_ATCC_1997 AQAATHGRFQLGLGLGAPVIEGPSYGLHVDKPIRRLREYLITLRQLLDA- Mflv_0410|M.gilvum_PYR-GCK VSLASNGRFILGLGMTHAAVTEGMWGIPWDKPVRRLNEYLDGLLPLLAG- Mvan_0261|M.vanbaalenii_PYR-1 VSLASGGRFILGLGMTHAAVTEGMWGIPWDRPVRRLNEYLDGLLPLLAG- TH_3430|M.thermoresistible__bu LSLISGGRFLLGIGMSHRMVAEGMWGVSWDRPVRQMREYLDGLQPLLAG- MMAR_4796|M.marinum_M VHAATGGRLVLGVGPSHHWIVDDMLGLPYQRPAAYTRDYLEVLAAALANP MUL_0365|M.ulcerans_Agy99 VHAATGGRLVLGVGPSHHWIVDDMLGLPYQRPAAYTRDYLEVLAAALANP Mb3120c|M.bovis_AF2122/97 VASLTGCRVDLALGASSPAIVAGWHGRPWAHHVPVMRETIECLRSIFTG- Rv3093c|M.tuberculosis_H37Rv VASLTGCRVDLALGASSPAIVAGWHGRPWAHHVPVMRETIECLRSIFTG- MLBr_00348|M.leprae_Br4923 LDHLSGGRHILGLGVSGPQVVEGWYGQPFPKPLSRTREYIDIVRQVWARE : . *.:* : * . .: : : MAV_3337|M.avium_104 GAVDFHGSELSA---------APSFPVRVPG--GTPIPVYVAAMGPKALQ MSMEG_5732|M.smegmatis_MC2_155 GDANFRGAEYSI---------ELQWPVQVAG--GTPIPIYVAAMGPKALR MAB_1339|M.abscessus_ATCC_1997 GTADFHGQTLTV---------APQFTTSQPG--GENIPVLVAAMAPQALR Mflv_0410|M.gilvum_PYR-GCK EPANATGETVTT---------RGALMIPG----APRPDVYIAALGPQLLR Mvan_0261|M.vanbaalenii_PYR-1 EPANATGETVTT---------RGALVIPG----APRPDVYIAALGPQLLR TH_3430|M.thermoresistible__bu RPADVTGEFWST---------RGALRLAGGGTSPPEPPVYLAALGPQMLR MMAR_4796|M.marinum_M GPVDVENDSFRV---------HNPLDLAAVA----PLPVLVAALGPVMLT MUL_0365|M.ulcerans_Agy99 GPVDVENDSFRV---------HNPLDLAAVA----PLPVLVAALGPVMLT Mb3120c|M.bovis_AF2122/97 ARVEYSGRHVNS---------RGFRLRGAAP----DTRIALGAFGPGMIR Rv3093c|M.tuberculosis_H37Rv ARVEYSGRHVNS---------RGFRLRGAAP----DTRIALGAFGPGMIR MLBr_00348|M.leprae_Br4923 APVVSDGQHYPLPLTGAGATGLGKALKPITHPLRADIPIMLGAEGPKNVA . . : :.* .* : MAV_3337|M.avium_104 VTGELADGTLPYLAGPRTIEEFIVPRIT-KAAAEAGRPAP--RIIAAVPV MSMEG_5732|M.smegmatis_MC2_155 ITGEYADGTLPYLAGPRTLSEFIVPTIN-DAAEAAGRPQP--RVTAMVPV MAB_1339|M.abscessus_ATCC_1997 ATGELADGTIPLHAGPRALGQEVVPVIS-AAAERAGRPRP--RVIAGVAV Mflv_0410|M.gilvum_PYR-GCK LAGRRTQGTCTWMTGPATLRDHVSPTLR-QAAADAGRPDGSVRVVASLPV Mvan_0261|M.vanbaalenii_PYR-1 VAGRRTAGTCTWMTGPATLRDHVSPALR-QAAADAGRPPGSVRVVASLPV TH_3430|M.thermoresistible__bu LAGRRTAGTLTWMTGPKTLAGHIVPTLR-QAAADAGRSGSDVRVVASLPV MMAR_4796|M.marinum_M LAGERADGTVLWMADERAVAEHVVPRIS-KAADNAGRPAP--RIVAGIPV MUL_0365|M.ulcerans_Agy99 LAGERADGTVLWMADERAVAEHVVPRIS-KAADNAGRPVP--RIVAGIPV Mb3120c|M.bovis_AF2122/97 LAAQHADEVVLNLASPFRVG-RVRAAID-SAAAAAGRAAP--RLTVWVPV Rv3093c|M.tuberculosis_H37Rv LAAQHADEVVLNLASPFRVG-RVRAAID-SAAAAAGRAAP--RLTVCVPV MLBr_00348|M.leprae_Br4923 LAAEICDGWLPIFFSPRMADMYNEWLDEGFARTGARRSREDFEICASAQI :.. . * * *. .: . : MAV_3337|M.avium_104 LLSD----------------------DVEGARAAAAQQLSFYETIPSYRN MSMEG_5732|M.smegmatis_MC2_155 VLSD----------------------DAETARRTAAEQLAFYATIPSYQK MAB_1339|M.abscessus_ATCC_1997 VVTS----------------------EPERVRALAIEDMAFYENIPSYRK Mflv_0410|M.gilvum_PYR-GCK AVTD----------------------DVDELRKQAADQFAMYGTLPSYRA Mvan_0261|M.vanbaalenii_PYR-1 AVTD----------------------DVEAARKQAAEQFAVYGTLPSYRA TH_3430|M.thermoresistible__bu SVTD----------------------DVEGARAQAVEQFAVYGTLPSYRA MMAR_4796|M.marinum_M CLCGS--------------------SEVEVARDRANRILGEAEVSPNYQR MUL_0365|M.ulcerans_Agy99 CLCGS--------------------SEVEVARDRANRILGEAEVSPNYQR Mb3120c|M.bovis_AF2122/97 AVNP-----------------------GAAAHSQLAAQLAVYLAPPGYGE Rv3093c|M.tuberculosis_H37Rv AVNP-----------------------GAAAHSQLAAQLAVYLAPPGYGE MLBr_00348|M.leprae_Br4923 VVTEDRAAAFAGIKPFLALYMGGMGAEGTNFHADVYRRMGYAEVVDEVTA : : :. MAV_3337|M.avium_104 VIAREGLSNAV----------------------ELAAIGPEESVLRQVRR MSMEG_5732|M.smegmatis_MC2_155 VIAREGISDLT----------------------ELAALGSPDQVREKLQS MAB_1339|M.abscessus_ATCC_1997 VLDAEGVQHTG----------------------ELAIIGDEQHVATELQR Mflv_0410|M.gilvum_PYR-GCK MLDREGYAGPE----------------------DAAIIGDEATVRDQIAE Mvan_0261|M.vanbaalenii_PYR-1 MLDREGYAGPE----------------------DAAIIGDEATVRDRLAE TH_3430|M.thermoresistible__bu MLDREGYVNPE----------------------DAAIIGDEQTVSQRLDE MMAR_4796|M.marinum_M LLGYGDAKDVG----------------------DICAAGDEDAILARFRR MUL_0365|M.ulcerans_Agy99 LLGHGDAKDVG----------------------DICAAGDEDAILARFRR Mb3120c|M.bovis_AF2122/97 MFSALGFDGLVRSARSRATRRELAVAVPSELLDRVCALGSPDRVAARLRA Rv3093c|M.tuberculosis_H37Rv MFSALGFDGLVRSARSRATRRELAVAVPSELLDRVCALGSPDRVAARLRA MLBr_00348|M.leprae_Br4923 LFRSNQKDKAAEIIPN-------------ELVDSTMIVGDVDYVCKQIAA :: * : .. MAV_3337|M.avium_104 YFDAGATDVVLSPLDRSAS-----VDREALWRLTAAL------- MSMEG_5732|M.smegmatis_MC2_155 YLDAGATDVVLSPLQVEQ------NDLEELWAVAASL------- MAB_1339|M.abscessus_ATCC_1997 YFDAGATEVFASHTELGGP-----QDEARTLALLGELSRGN--- Mflv_0410|M.gilvum_PYR-GCK LGAAGVDEYVGAVFDSSV------EGRDRTRALLRELG------ Mvan_0261|M.vanbaalenii_PYR-1 LAEAGVDEYVGAVFDSSA------EGRDRTRALLRDMRSGG--- TH_3430|M.thermoresistible__bu LAAAGVDEFTAAVFDADP------EIRARTRALLVSRQTG---- MMAR_4796|M.marinum_M FAEAGVTDLSVRLLPIGDNREELVASKRRTRDMIATLATEVR-- MUL_0365|M.ulcerans_Agy99 FAEAGVTDLSVRLLPIGDNREELVASKRRTRDMIATLATEVR-- Mb3120c|M.bovis_AF2122/97 YADAGADCVAVVPATAEDPGGRVALRALRPGGLYGTAGDNDGRR Rv3093c|M.tuberculosis_H37Rv YADAGADCVAVVPATAEDPGGRVALRALRPGGLYGTAGDNDGRR MLBr_00348|M.leprae_Br4923 WSAAGVTMMMVSAS-----------SVEQVRDLAGLF------- **. :