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MTDIEVALPFWLDRPDHEATDVALAAADTGFAALWIGEMATYDAFALATSIGLRTPNMTLKVGPLAVGVR GPVGLALGVSSVASLTGCRVDLALGASSPAIVAGWHGRPWAHHVPVMRETIECLRSIFTGARVEYSGRHV NSRGFRLRGAAPDTRIALGAFGPGMIRLAAQHADEVVLNLASPFRVGRVRAAIDSAAAAAGRAAPRLTVW VPVAVNPGAAAHSQLAAQLAVYLAPPGYGEMFSALGFDGLVRSARSRATRRELAVAVPSELLDRVCALGS PDRVAARLRAYADAGADCVAVVPATAEDPGGRVALRALRPGGLYGTAGDNDGRR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3120c | - | - | 100% (334) | oxidoreductase |
| M. bovis AF2122 / 97 | Mb3550c | - | 3e-19 | 25.30% (336) | coenzyme F420-dependent oxidoreductase |
| M. bovis AF2122 / 97 | Mb0815c | - | 3e-08 | 22.88% (306) | hypothetical protein Mb0815c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2453 | - | 2e-17 | 28.99% (307) | luciferase family protein |
| M. tuberculosis H37Rv | Rv3093c | - | 0.0 | 99.70% (334) | oxidoreductase |
| M. leprae Br4923 | MLBr_00348 | - | 1e-20 | 25.91% (328) | putative coenzyme F420-dependent oxidoreductase |
| M. abscessus ATCC 19977 | MAB_3748 | - | 1e-16 | 24.39% (328) | putative luciferase-like oxidoreductase |
| M. marinum M | MMAR_1557 | - | 1e-141 | 78.64% (323) | oxidoreductase |
| M. avium 104 | MAV_3337 | - | 4e-20 | 25.84% (298) | monooxygenase |
| M. smegmatis MC2 155 | MSMEG_5732 | - | 7e-21 | 27.24% (290) | monooxygenase |
| M. thermoresistible (build 8) | TH_1703 | - | 5e-17 | 24.53% (318) | oxidoreductase |
| M. ulcerans Agy99 | MUL_4782 | - | 6e-23 | 29.58% (311) | coenzyme F420-dependent oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_0261 | - | 5e-18 | 27.96% (304) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3120c|M.bovis_AF2122/97 ----MTDIEVALPFWLDRPD----HEATDVALAAADTGFAALWIGEMA-T
Rv3093c|M.tuberculosis_H37Rv ----MTDIEVALPFWLDRPD----HEATDVALAAADTGFAALWIGEMA-T
MMAR_1557|M.marinum_M ----MTDLEVALPFWLDRPD----DEAMEVALAASNAGFDVLWVGEMA-T
MAV_3337|M.avium_104 -----MSAGIILMAHPDAAN--LVDDVIAQARRAHELGVGQVWLAQQQ-S
MSMEG_5732|M.smegmatis_MC2_155 ---MIMPTGVMLRINPSAAN--AIDGLIADARRAHDIGVKQIWLAQQA-D
Mflv_2453|M.gilvum_PYR-GCK -----MRIGLMVGSDRERARPDRLAGLIEDGIAAETAGFNSFWFPQVPGY
Mvan_0261|M.vanbaalenii_PYR-1 -----MQISMFGQISGLGGN--PIDATIAYLSQLRDEGFARVWISQLPYE
MAB_3748|M.abscessus_ATCC_1997 -------MRIGTTLSYAGG----FTEVVDELAELEKIGLDIAFVAEAY-S
TH_1703|M.thermoresistible__bu -------MRIGMQLAYSGG----FKETAGLVVELEKVGLDLAVVPEAY-S
MLBr_00348|M.leprae_Br4923 MVERANAMKLGLQLGYWAAQ--PPGNAAELVAAAEGAGFDAVFTGEAW-G
MUL_4782|M.ulcerans_Agy99 -------MRTATTVELSGGK--DGKDTVDFVVEAEKLGLHTCWVAEAW-G
*. :
Mb3120c|M.bovis_AF2122/97 YDAFALATSIGLRTPNMTLKVGPLAVGVRGPVGLALGVSSVASLTGCRVD
Rv3093c|M.tuberculosis_H37Rv YDAFALATSIGLRTPNMTLKVGPLAVGVRGPVGLALGVSSVASLTGCRVD
MMAR_1557|M.marinum_M YDAFALATAIGLGAPGMGLKIGPLAVAVRGPVGLALGVSSVASLTGSRVD
MAV_3337|M.avium_104 YDAIALAALVGAAVPGLGVGTSVVPINPRHPLIVASLAQTAQAAAHGRFS
MSMEG_5732|M.smegmatis_MC2_155 IDAIAAAGLIGAAVPGLGVGTAVVPINPRHPLVISAAAQTAQAAAHGNFT
Mflv_2453|M.gilvum_PYR-GCK LDAMTTVALLGASTSSIEIGTAVIPVQTRHPLILAQQALTTNAACGGRFA
Mvan_0261|M.vanbaalenii_PYR-1 PDLLTILAVALREVDTIEVASGVVPIQNQHPMQMAQRALTVSLASGGRFI
MAB_3748|M.abscessus_ATCC_1997 YDAASQLGYLAAKTSTVKLASGIFQLYTRTPTLLAMTAAGLDYVSGGRFV
TH_1703|M.thermoresistible__bu FDAISQLGYLAARTSTIQLATGVVPIYTRTPALLAMTAAGLDYVSDGRFT
MLBr_00348|M.leprae_Br4923 SDAYTPLAWWGSSTQRVRLGTSVVQLSARTPTACAMAALTLDHLSGGRHI
MUL_4782|M.ulcerans_Agy99 SDAPSALGYIAARTERMQLGSGVLQVGTRSPVLVAQTAITLSNLSCGRFL
* : . : : . . : : * : . .
Mb3120c|M.bovis_AF2122/97 LALGASSPAIVAGWHGRPWAHHVPVMRETIECLRSIFT-GARVEYSGRHV
Rv3093c|M.tuberculosis_H37Rv LALGASSPAIVAGWHGRPWAHHVPVMRETIECLRSIFT-GARVEYSGRHV
MMAR_1557|M.marinum_M IALGASSPAIVAGWHDRPWAHHVPVMRETIECLRSILG-GARVDYHGRHV
MAV_3337|M.avium_104 LGLGLGAADLERRTFGTEWPNTITRLREHLTILGSVFH-SGAVDFHGSEL
MSMEG_5732|M.smegmatis_MC2_155 LGLGLGARVIEHYAFGIDRTNTVNRLHEYLQVLRGAFE-RGDANFRGAEY
Mflv_2453|M.gilvum_PYR-GCK LGLGLSHDWIINGQLGLPYQRPVHTLRDHLDVLAAAFAGPGQVDVDNDTF
Mvan_0261|M.vanbaalenii_PYR-1 LGLGMTHAAVTEGMWGIPWDRPVRRLNEYLDGLLPLLA-GEPANATGETV
MAB_3748|M.abscessus_ATCC_1997 LGIGASGPQVIEGFHGVKYDAPLGRTRETVEICRKVWRRER-LEFEGKYF
TH_1703|M.thermoresistible__bu LGLGTSGPQVVEGFHGVPFDAPLGRTREVVEICRKVWRRER-LQYNGRHY
MLBr_00348|M.leprae_Br4923 LGLGVSGPQVVEGWYGQPFPKPLSRTREYIDIVRQVWAREAPVVSDGQHY
MUL_4782|M.ulcerans_Agy99 LGLGASGPRVIEGLHGVAFDRPLARLKETVEIVRQVFAGGK-VTYSGSEF
:.:* : . : .: : .
Mb3120c|M.bovis_AF2122/97 NSRG-------------FRLRGAAPDTRIALGAFGPGMIRLAAQHADEVV
Rv3093c|M.tuberculosis_H37Rv NSRG-------------FRLRGAAPDTRIALGAFGPGMIRLAAQHADEVV
MMAR_1557|M.marinum_M ASHG-------------FRLRNPQPEARIALGAFGPGMIRLAARHADEVV
MAV_3337|M.avium_104 SAAPSF-----------PVRVPGGTPIPVYVAAMGPKALQVTGELADGTL
MSMEG_5732|M.smegmatis_MC2_155 SIELQW-----------PVQVAGGTPIPIYVAAMGPKALRITGEYADGTL
Mflv_2453|M.gilvum_PYR-GCK HVHS-------------PVDVAD-TAPALLLAALGPTMLRIAGERADGTV
Mvan_0261|M.vanbaalenii_PYR-1 TTRG-------------ALVIPGAPRPDVYIAALGPQLLRVAGRRTAGTC
MAB_3748|M.abscessus_ATCC_1997 TVPLPPEQGTGLGKALKLINHPVRDRIPVLIAALGPKNVALTAEIAEGWQ
TH_1703|M.thermoresistible__bu HLPLPPDRGTGLGKPLKLINHPVREHIPIFIAALGPKNVQLTAEIADGWQ
MLBr_00348|M.leprae_Br4923 PLPLTGAGATGLGKALKPITHPLRADIPIMLGAEGPKNVALAAEICDGWL
MUL_4782|M.ulcerans_Agy99 QIPRRG----GEARPMRLSTRPEYD-IPIYLAALSPAMLRLTGRIADGWL
: :.* .* : ::..
Mb3120c|M.bovis_AF2122/97 LNLASPFRVGR--VRAAIDSAAAAAG-RAAPRLTVWVPVAVNP------G
Rv3093c|M.tuberculosis_H37Rv LNLASPFRVGR--VRAAIDSAAAAAG-RAAPRLTVCVPVAVNP------G
MMAR_1557|M.marinum_M LNLASPARVAE--VRHAIDSAAAAAAGRAAPRLTVWVPVAVDP------G
MAV_3337|M.avium_104 PYLAGPRTIEEFIVPRITKAAAEAGRP--APRIIAAVPVLLSD-----DV
MSMEG_5732|M.smegmatis_MC2_155 PYLAGPRTLSEFIVPTINDAAEAAGRP--QPRVTAMVPVVLSD-----DA
Mflv_2453|M.gilvum_PYR-GCK LWMADERAIGEHVVPRIGAAAQGAGRP--APRVVAGVPVALCEP---ADV
Mvan_0261|M.vanbaalenii_PYR-1 TWMTGPATLRDHVSPALRQAAADAGRPPGSVRVVASLPVAVTD-----DV
MAB_3748|M.abscessus_ATCC_1997 PIFFLPEKANDVWGAALAEGKAKRDP--ALGDLEVYAGPALAIG---DDV
TH_1703|M.thermoresistible__bu PVFVDPERIDSVWGDALRAGRAKRDP--TLGPLDVMGTPPLAIG---DDV
MLBr_00348|M.leprae_Br4923 PIFFSP-RMADMYNEWLDEGFARTGARRSREDFEICASAQIVVT---EDR
MUL_4782|M.ulcerans_Agy99 GTSFVPEGAGDAYFTHLDAGLAAAGR--SRADIDFCQGAEVAFASGVEEL
. . :
Mb3120c|M.bovis_AF2122/97 AAAHSQLAAQLAVYLA------PPGYGEMFSALGFDGLVRSARSRA---T
Rv3093c|M.tuberculosis_H37Rv AAAHSQLAAQLAVYLA------PPGYGEMFSALGFDGLVRSARSRA---T
MMAR_1557|M.marinum_M AAAHAQLAAQLAVYLG------PPGYGEMFSALGFDRLVGAARAGA---S
MAV_3337|M.avium_104 EGARAAAAQQLSFYET------IPSYRNVIAREGLSNAV-----------
MSMEG_5732|M.smegmatis_MC2_155 ETARRTAAEQLAFYAT------IPSYQKVIAREGISDLT-----------
Mflv_2453|M.gilvum_PYR-GCK DDARAHASEILGHAHL------SPNYVALLEHGDADDVG-----------
Mvan_0261|M.vanbaalenii_PYR-1 EAARKQAAEQFAVYGT------LPSYRAMLDREGYAGPE-----------
MAB_3748|M.abscessus_ATCC_1997 EALYGFVKPSLALYIGGMGAKGKNFYHNLATAYGFGKEADTIQELYLSGK
TH_1703|M.thermoresistible__bu EDRIAWVKPMLALYLGGMGARDKNFYHNLATRYGFGAEADRIQELYLAGR
MLBr_00348|M.leprae_Br4923 AAAFAGIKPFLALYMGGMGAEGTNFHADVYRRMGYAEVVDEVTALFRSNQ
MUL_4782|M.ulcerans_Agy99 RDMVAARKTELAFSLGGMGSASTNYYNQAYSRQGWSEVAAAVRERWQRGD
:. : .
Mb3120c|M.bovis_AF2122/97 RRELAVAVPSELLDRVCALGSPDRVAARLRAYADAGADCVAVVPATAEDP
Rv3093c|M.tuberculosis_H37Rv RRELAVAVPSELLDRVCALGSPDRVAARLRAYADAGADCVAVVPATAEDP
MMAR_1557|M.marinum_M RRELAAAIPVELLEQVGALGTAERVAARLRDYEAAGADCLALVPCTAEDP
MAV_3337|M.avium_104 --------------ELAAIGPEESVLRQVRRYFDAGATDVVLSPLDRSAS
MSMEG_5732|M.smegmatis_MC2_155 --------------ELAALGSPDQVREKLQSYLDAGATDVVLSPLQVEQ-
Mflv_2453|M.gilvum_PYR-GCK --------------DTMAAGDESAVLTRLRAYRDAGVTDLAARVIPLGDT
Mvan_0261|M.vanbaalenii_PYR-1 --------------DAAIIGDEATVRDRLAELAEAGVDEYVGAVFDSSAE
MAB_3748|M.abscessus_ATCC_1997 KAEATDAVPDELVKNISLIGPKSFVAERVAAFKEAGVTTLNVAPLAADAA
TH_1703|M.thermoresistible__bu KEEAAAAVPDDLVRSVSLIGPAGLVAERVAMFAEAGVTTLLVTPLATDTA
MLBr_00348|M.leprae_Br4923 KDKAAEIIPNELVDSTMIVGDVDYVCKQIAAWSAAGVTMMMVS------A
MUL_4782|M.ulcerans_Agy99 REGAARLVTDEMVLATTLIGTEEMVRSRLVAWRDAGVNTVRLYPAGDTMD
* * :: **.
Mb3120c|M.bovis_AF2122/97 ---------GGRVALRALRPGGLYGTAGDNDGRR
Rv3093c|M.tuberculosis_H37Rv ---------GGRVALRALRPGGLYGTAGDNDGRR
MMAR_1557|M.marinum_M ---------AGRATLNALS------RKGES----
MAV_3337|M.avium_104 ---------VDREALWRLTAAL------------
MSMEG_5732|M.smegmatis_MC2_155 ---------NDLEELWAVAASL------------
Mflv_2453|M.gilvum_PYR-GCK PARRHQSRRRTAEFLASVAAGL------------
Mvan_0261|M.vanbaalenii_PYR-1 ------GRDRTRALLRDMRSGG------------
MAB_3748|M.abscessus_ATCC_1997 GRIK------HVEALRELL---------------
TH_1703|M.thermoresistible__bu EAVR------FIEQLRTMVA--------------
MLBr_00348|M.leprae_Br4923 SSVE------QVRDLAGLF---------------
MUL_4782|M.ulcerans_Agy99 AKLS------TLGRAIELVRAVR-----------
: