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IMPTGVMLRINPSAANAIDGLIADARRAHDIGVKQIWLAQQADIDAIAAAGLIGAAVPGLGVGTAVVPIN PRHPLVISAAAQTAQAAAHGNFTLGLGLGARVIEHYAFGIDRTNTVNRLHEYLQVLRGAFERGDANFRGA EYSIELQWPVQVAGGTPIPIYVAAMGPKALRITGEYADGTLPYLAGPRTLSEFIVPTINDAAEAAGRPQP RVTAMVPVVLSDDAETARRTAAEQLAFYATIPSYQKVIAREGISDLTELAALGSPDQVREKLQSYLDAGA TDVVLSPLQVEQNDLEELWAVAASL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5732 | - | - | 100% (306) | monooxygenase |
| M. smegmatis MC2 155 | MSMEG_4879 | - | 5e-38 | 32.14% (280) | hypothetical protein MSMEG_4879 |
| M. smegmatis MC2 155 | MSMEG_0528 | - | 1e-36 | 31.72% (290) | hypothetical protein MSMEG_0528 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3120c | - | 4e-21 | 27.24% (290) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_2453 | - | 4e-41 | 37.45% (267) | luciferase family protein |
| M. tuberculosis H37Rv | Rv3093c | - | 4e-21 | 27.24% (290) | oxidoreductase |
| M. leprae Br4923 | MLBr_00131 | - | 6e-11 | 29.59% (169) | putative oxidoreductase |
| M. abscessus ATCC 19977 | MAB_1339 | - | 1e-71 | 49.64% (274) | putative monooxygenase (luciferase-like) |
| M. marinum M | MMAR_4796 | - | 1e-36 | 32.39% (284) | oxidoreductase |
| M. avium 104 | MAV_3337 | - | 1e-105 | 61.31% (305) | monooxygenase |
| M. thermoresistible (build 8) | TH_3430 | - | 9e-44 | 35.36% (280) | PUTATIVE luciferase family protein |
| M. ulcerans Agy99 | MUL_0365 | - | 5e-37 | 32.39% (284) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_4198 | - | 4e-43 | 37.92% (269) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3120c|M.bovis_AF2122/97 -------------------------MTDIEVALP-----FWLDRPDHEAT
Rv3093c|M.tuberculosis_H37Rv -------------------------MTDIEVALP-----FWLDRPDHEAT
MSMEG_5732|M.smegmatis_MC2_155 ------------------------MIMPTGVML---RINPSAANAIDGLI
MAV_3337|M.avium_104 --------------------------MSAGIIL---MAHPDAANLVDDVI
MAB_1339|M.abscessus_ATCC_1997 --------------------------MKLGVAIGRPLSVQNSTNLVDTFI
TH_3430|M.thermoresistible__bu -------------VNRPTTHRMGVLMAGMRISLSIVGLTPDGPDPIDSLV
Mflv_2453|M.gilvum_PYR-GCK --------------------------MRIGLMVG-SDRERARPDRLAGLI
Mvan_4198|M.vanbaalenii_PYR-1 --------------------------MRIGLMVG-SDRDRPRPDRLDGVI
MMAR_4796|M.marinum_M --------------------------MRVGVMIG-PERGDSG-RKVGRML
MUL_0365|M.ulcerans_Agy99 --------------------------MRVGVMIG-PERGDSG-RKVGRML
MLBr_00131|M.leprae_Br4923 MAGFRFGFVDALVHTLFPPSLPARASIVSGAVLG-ADSYWVGDHLNALVP
:
Mb3120c|M.bovis_AF2122/97 DVALAAADTGFAALWIGEM-ATYDAFALAT--SIGLRTPNMTLKVGPLAV
Rv3093c|M.tuberculosis_H37Rv DVALAAADTGFAALWIGEM-ATYDAFALAT--SIGLRTPNMTLKVGPLAV
MSMEG_5732|M.smegmatis_MC2_155 ADARRAHDIGVKQIWLAQQ-ADIDAIAAAG--LIGAAVPGLGVGTAVVPI
MAV_3337|M.avium_104 AQARRAHELGVGQVWLAQQ-QSYDAIALAA--LVGAAVPGLGVGTSVVPI
MAB_1339|M.abscessus_ATCC_1997 AHARRVAEAGVRTLWLGQM-YHYDSITMAA--VVGQTVPDVTVGVSVIPI
TH_3430|M.thermoresistible__bu RDLTALRDAGFGRVWLAQLPFDIDLPTVLG--IALRAVDGIEVGSGVIPI
Mflv_2453|M.gilvum_PYR-GCK EDGIAAETAGFNSFWFPQVPGYLDAMTTVA--LLGASTSSIEIGTAVIPV
Mvan_4198|M.vanbaalenii_PYR-1 TDGTAAEALGFSSFWFPQVPGYLDAMTALA--LLGASTTTIELGTAVVPI
MMAR_4796|M.marinum_M ADIDWAETAGLDSAWIPQIPNDFDALVAVT--LMGTRSSRIELGTAVVPL
MUL_0365|M.ulcerans_Agy99 ADIDWAETAGLDSAWIPQIPNDFDALVAVT--LMGTRSSRIELGTAVVPL
MLBr_00131|M.leprae_Br4923 RSVATPKYLGVAAKVVPKIDANYEPWTMLGNLAAGNRLNGLRLGVCVTDA
*. . : : . : :
Mb3120c|M.bovis_AF2122/97 GVRGPVGLALGVSSVASLTGCRVDLALGASSPAIVAGWHGRPWAHHVPVM
Rv3093c|M.tuberculosis_H37Rv GVRGPVGLALGVSSVASLTGCRVDLALGASSPAIVAGWHGRPWAHHVPVM
MSMEG_5732|M.smegmatis_MC2_155 NPRHPLVISAAAQTAQAAAHGNFTLGLGLGARVIEHYAFGIDRTNTVNRL
MAV_3337|M.avium_104 NPRHPLIVASLAQTAQAAAHGRFSLGLGLGAADLERRTFGTEWPNTITRL
MAB_1339|M.abscessus_ATCC_1997 NPRHPIEVSAAAQTAQAATHGRFQLGLGLGAPVIEGPSYGLHVDKPIRRL
TH_3430|M.thermoresistible__bu QPQHPMQLAQRALTLSLISGGRFLLGIGMSHRMVAEGMWGVSWDRPVRQM
Mflv_2453|M.gilvum_PYR-GCK QTRHPLILAQQALTTNAACGGRFALGLGLSHDWIINGQLGLPYQRPVHTL
Mvan_4198|M.vanbaalenii_PYR-1 QTRHPMILAQQGLTTNAACGGRFTLGLGLSHDWIINGQLGIPYQRPVREL
MMAR_4796|M.marinum_M QTQHPIALARQALSVHAATGGRLVLGVGPSHHWIVDDMLGLPYQRPAAYT
MUL_0365|M.ulcerans_Agy99 QTQHPIALARQALSVHAATGGRLVLGVGPSHHWIVDDMLGLPYQRPAAYT
MLBr_00131|M.leprae_Br4923 GRRNPAVTAQAAATLHLLTRGKAMLGIGVGEREGNEP-YGVEWTKPVARF
: * : : . *.:* . * .
Mb3120c|M.bovis_AF2122/97 RETIECLRSIFTGARVEYSGRHVNSRGF-RLRGAAPDTR----IALGAFG
Rv3093c|M.tuberculosis_H37Rv RETIECLRSIFTGARVEYSGRHVNSRGF-RLRGAAPDTR----IALGAFG
MSMEG_5732|M.smegmatis_MC2_155 HEYLQVLRGAFERGDANFRGAEYSIELQ-WPVQVAGGTP--IPIYVAAMG
MAV_3337|M.avium_104 REHLTILGSVFHSGAVDFHGSELSAAPS-FPVRVPGGTP--IPVYVAAMG
MAB_1339|M.abscessus_ATCC_1997 REYLITLRQLLDAGTADFHGQTLTVAPQ-FTTSQPGGEN--IPVLVAAMA
TH_3430|M.thermoresistible__bu REYLDGLQPLLAGRPADVTGEFWSTRGA-LRLAGGGTSPPEPPVYLAALG
Mflv_2453|M.gilvum_PYR-GCK RDHLDVLAAAFA-GPGQVDVDNDTFHVH-SPVDVADTAP---ALLLAALG
Mvan_4198|M.vanbaalenii_PYR-1 RDHLEVLTAAFD-GPGQVDVDNDSFRVH-SPVDVSDLSP---PVLLAALG
MMAR_4796|M.marinum_M RDYLEVLAAALA-NPGPVDVENDSFRVH-NPLDLAAVAPL--PVLVAALG
MUL_0365|M.ulcerans_Agy99 RDYLEVLAAALA-NPGPVDVENDSFRVH-NPLDLAAVAPL--PVLVAALG
MLBr_00131|M.leprae_Br4923 QEALATIRALWDSNGELVSRESQFFPLHNALFDLPPYRGKWPEIWVAAHG
:: : : : :.* .
Mb3120c|M.bovis_AF2122/97 PGMIRLAAQHADEVVLNLASPFRVGR-VRAAIDSAAAAAGRAAP--RLTV
Rv3093c|M.tuberculosis_H37Rv PGMIRLAAQHADEVVLNLASPFRVGR-VRAAIDSAAAAAGRAAP--RLTV
MSMEG_5732|M.smegmatis_MC2_155 PKALRITGEYADGTLPYLAGPRTLSEFIVPTINDAAEAAGRPQP--RVTA
MAV_3337|M.avium_104 PKALQVTGELADGTLPYLAGPRTIEEFIVPRITKAAAEAGRPAP--RIIA
MAB_1339|M.abscessus_ATCC_1997 PQALRATGELADGTIPLHAGPRALGQEVVPVISAAAERAGRPRP--RVIA
TH_3430|M.thermoresistible__bu PQMLRLAGRRTAGTLTWMTGPKTLAGHIVPTLRQAAADAGRSGSDVRVVA
Mflv_2453|M.gilvum_PYR-GCK PTMLRIAGERADGTVLWMADERAIGEHVVPRIGAAAQGAGRPAP--RVVA
Mvan_4198|M.vanbaalenii_PYR-1 PTMLRIAGERTDGTILWMADERAIAEHVAPRITAAAHAAGRPAP--RVVA
MMAR_4796|M.marinum_M PVMLTLAGERADGTVLWMADERAVAEHVVPRISKAADNAGRPAP--RIVA
MUL_0365|M.ulcerans_Agy99 PVMLTLAGERADGTVLWMADERAVAEHVVPRISKAADNAGRPVP--RIVA
MLBr_00131|M.leprae_Br4923 PRMLQATGRYADAWIPIVLVRPTDYSCALEVVRTAASDAGRDPMSITPAA
* : :.. : : : ** *** .
Mb3120c|M.bovis_AF2122/97 WVPVAVNP---GAAAHSQLAAQLAVYLAPP---------GYGEMFSALGF
Rv3093c|M.tuberculosis_H37Rv CVPVAVNP---GAAAHSQLAAQLAVYLAPP---------GYGEMFSALGF
MSMEG_5732|M.smegmatis_MC2_155 MVPVVLSD--DAETARRTAAEQLAFYATIP---------SYQKVIAREGI
MAV_3337|M.avium_104 AVPVLLSD--DVEGARAAAAQQLSFYETIP---------SYRNVIAREGL
MAB_1339|M.abscessus_ATCC_1997 GVAVVVTS--EPERVRALAIEDMAFYENIP---------SYRKVLDAEGV
TH_3430|M.thermoresistible__bu SLPVSVTD--DVEGARAQAVEQFAVYGTLP---------SYRAMLDREGY
Mflv_2453|M.gilvum_PYR-GCK GVPVALCEPADVDDARAHASEILGHAHLSP---------NYVALLEHGDA
Mvan_4198|M.vanbaalenii_PYR-1 GVPVAVCAPGDVDAAQRYASELLGHAHFSP---------NYVALLEHGDA
MMAR_4796|M.marinum_M GIPVCLCGSSEVEVARDRANRILGEAEVSP---------NYQRLLGYGDA
MUL_0365|M.ulcerans_Agy99 GIPVCLCGSSEVEVARDRANRILGEAEVSP---------NYQRLLGHGDA
MLBr_00131|M.leprae_Br4923 VRGIITGRTRDDVDEALDSVLVRMIALGVPGEAWARHGVEHPMGADFAGV
: * : .
Mb3120c|M.bovis_AF2122/97 DGLVRSARSRATRRELAVAVPSELLDRVCALGSPDRVAARLRAYADAGAD
Rv3093c|M.tuberculosis_H37Rv DGLVRSARSRATRRELAVAVPSELLDRVCALGSPDRVAARLRAYADAGAD
MSMEG_5732|M.smegmatis_MC2_155 SDLT----------------------ELAALGSPDQVREKLQSYLDAGAT
MAV_3337|M.avium_104 SNAV----------------------ELAAIGPEESVLRQVRRYFDAGAT
MAB_1339|M.abscessus_ATCC_1997 QHTG----------------------ELAIIGDEQHVATELQRYFDAGAT
TH_3430|M.thermoresistible__bu VNPE----------------------DAAIIGDEQTVSQRLDELAAAGVD
Mflv_2453|M.gilvum_PYR-GCK DDVG----------------------DTMAAGDESAVLTRLRAYRDAGVT
Mvan_4198|M.vanbaalenii_PYR-1 ADVG----------------------DTMAAGDESCVLNRLRAYRDAGVT
MMAR_4796|M.marinum_M KDVG----------------------DICAAGDEDAILARFRRFAEAGVT
MUL_0365|M.ulcerans_Agy99 KDVG----------------------DICAAGDEDAILARFRRFAEAGVT
MLBr_00131|M.leprae_Br4923 QDIIPQTIDEETVVSYAAKVPAALMKEVLFSGTPEEVIDQVAEWRDHGLK
* . : .. *
Mb3120c|M.bovis_AF2122/97 CVAVVPATAEDPGGRVALRALRPGGLYGTAGDNDGRR
Rv3093c|M.tuberculosis_H37Rv CVAVVPATAEDPGGRVALRALRPGGLYGTAGDNDGRR
MSMEG_5732|M.smegmatis_MC2_155 DVVLSPLQVEQ-NDLEELWAVAASL------------
MAV_3337|M.avium_104 DVVLSPLDRSASVDREALWRLTAAL------------
MAB_1339|M.abscessus_ATCC_1997 EVFASHTELGGPQDEARTLALLGELSRGN--------
TH_3430|M.thermoresistible__bu EFTAAVFDADPEIRARTRALLVSRQTG----------
Mflv_2453|M.gilvum_PYR-GCK DLAARVIPLGDTPARRHQSRRRTAEFLASVAAGL---
Mvan_4198|M.vanbaalenii_PYR-1 DLAARIVPLGDDPASRRRSRERTAEFLASVVSEF---
MMAR_4796|M.marinum_M DLSVRLLPIGDNREELVASKRRTRDMIATLATEVR--
MUL_0365|M.ulcerans_Agy99 DLSVRLLPIGDNREELVASKRRTRDMIATLATEVR--
MLBr_00131|M.leprae_Br4923 YLVVINGSLVNSSLRKTVSALLPHARVLRGLKKL---
.