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M. tuberculosis H37Rv Rv2948c (fadD22)

annotation: acyl-CoA synthetase
coordinates: 3297837 - 3299954
length: 705

RNGNLAGLLAEQASEAGWYDRPAFYAADVVTHGQIHDGAARLGEVLRNRGLSSGDRVLLCLPDSPDLVQL
LLACLARGVMAFLANPELHRDDHALAARNTEPALVVTSDALRDRFQPSRVAEAAELMSEAARVAPGGYEP
MGGDALAYATYTSGTTGPPKAAIHRHADPLTFVDAMCRKALRLTPEDTGLCSARMYFAYGLGNSVWFPLA
TGGSAVINSAPVTPEAAAILSARFGPSVLYGVPNFFARVIDSCSPDSFRSLRCVVSAGEALELGLAERLM
EFFGGIPILDGIGSTEVGQTFVSNRVDEWRLGTLGRVLPPYEIRVVAPDGTTAGPGVEGDLWVRGPAIAK
GYWNRPDSPVANEGWLDTRDRVCIDSDGWVTYRCRADDTEVIGGVNVDPREVERLIIEDEAVAEAAVVAV
RESTGASTLQAFLVATSGATIDGSVMRDLHRGLLNRLSAFKVPHRFAVVDRLPRTPNGKLVRGALRKQSP
TKPIWELSLTEPGSGVRAQRDDLSASNMTIAGGNDGGATLRERLVALRQERQRLVVDAVCAEAAKMLGEP
DPWSVDQDLAFSELGFDSQMTVTLCKRLAAVTGLRLPETVGWDYGSISGLAQYLEAELAGGHGRLKSAGP
VNSGATGLWAIEEQLNKVEELVAVIADGEKQRVADRLRALLGTIAGSEAGLGKLIQAASTPDEIFQLIDS
ELGK*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv2948cfadD22-100% (705)acyl-CoA synthetase
M. tuberculosis H37RvRv2505cfadD354e-3327.48% (484) AMP-binding domain protein
M. tuberculosis H37RvRv3089fadD132e-2925.00% (516) chain-fatty-acid-CoA ligase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2972cfadD220.0100.00% (705) acyl-CoA synthetase
M. gilvum PYR-GCKMflv_5271-8e-3426.96% (497) AMP-dependent synthetase and ligase
M. leprae Br4923MLBr_00134fadD220.075.89% (705) acyl-CoA synthetase
M. abscessus ATCC 19977MAB_4569c-1e-3426.98% (493) fatty-acid-CoA ligase FadD
M. marinum MMMAR_1761fadD220.074.61% (705) fatty-acid-CoA ligase FadD22
M. avium 104MAV_2995-2e-3329.41% (493) adenylate-forming enzyme
M. smegmatis MC2 155MSMEG_5633-6e-3828.57% (504) feruloyl-CoA synthetase
M. thermoresistible (build 8)TH_3448-9e-4129.30% (512) PUTATIVE putative AMP-dependent synthetase and ligase
M. ulcerans Agy99MUL_2004fadD220.073.76% (705) acyl-CoA synthetase
M. vanbaalenii PYR-1Mvan_4968-3e-3627.44% (503) AMP-dependent synthetase and ligase

CLUSTAL 2.0.9 multiple sequence alignment


Rv2948c|M.tuberculosis_H37Rv        ----------------------------MRNGNLAGLLAEQASEAGWYDR
Mb2972c|M.bovis_AF2122/97           ----------------------------MRNGNLAGLLAEQASEAGWYDR
MLBr_00134|M.leprae_Br4923          ----------------------------MRSENLAALLARQAAEAGWYDK
MMAR_1761|M.marinum_M               ----------------------------MRNENVAGLLAERASEAGWTDQ
MUL_2004|M.ulcerans_Agy99           ----------------------------MRNENVAGLLAERASEAGWTDQ
Mflv_5271|M.gilvum_PYR-GCK          ---MSRGKRANPASGSGSRGTLLGMAELTEPRFLDERLAHWATVNPDGEA
MAB_4569c|M.abscessus_ATCC_199      ---MTDTIDATVQSAG------LAQPYRARRQNWCNQLARHALMQPDATA
MSMEG_5633|M.smegmatis_MC2_155      -------------------------------MNLFGLLDQTAARHGDRGA
Mvan_4968|M.vanbaalenii_PYR-1       -------------------------------MNLFALLDQTAARHGDRGA
TH_3448|M.thermoresistible__bu      -------------------------------MNLTMLLEMAAEAGPDRVA
MAV_2995|M.avium_104                MMSAGGLHTESSPAFSDEDVARFRAAGWWCDSTLSDAVRRNAQRTPERPA
                                                                         :   *        

Rv2948c|M.tuberculosis_H37Rv        PAFYAADVVTHGQIHDGAARLGEVLRNRG-LSSGDRVLLCLPDSPDLVQL
Mb2972c|M.bovis_AF2122/97           PAFYAADVVTHGQIHDGAARLGEVLRNRG-LSSGDRVLLCLPDSPDLVQL
MLBr_00134|M.leprae_Br4923          PAYFAPDVVTHGQIHDGAVRLGEVLRNRG-LSAGDRVLLCLPDSPDLVQL
MMAR_1761|M.marinum_M               PAYYAPDVVTHGQIHDGAARLGAVLANRG-LCRGDRVLLCMPDSPELVQV
MUL_2004|M.ulcerans_Agy99           PAYYAPDVVTHGQIHDGAARLGAVLANRG-LCRGDRVLLCMPDSPELVQV
Mflv_5271|M.gilvum_PYR-GCK          MDYLER-SWTWSQWNDRVRRLAGALTERG-ISRGDVVAFLDKNHPACVEL
MAB_4569c|M.abscessus_ATCC_199      IRYLGH-SISWAELHQRVQALADALSRRG-VGFGDRVLILMLNRPEYVES
MSMEG_5633|M.smegmatis_MC2_155      VFCGERELYTWTQLRDRAARLGSTLTE-----PGTRVAVASENRPEIIEI
Mvan_4968|M.vanbaalenii_PYR-1       VYHGERLVHTWSSLRERALRLASSLREF---GPGARIAVASENRPEIVEL
TH_3448|M.thermoresistible__bu      VGPRDG-GITYRQLLDRARALAGELIAPDQAAAPENVALLDLNSPAVPML
MAV_2995|M.avium_104                YIDHGGRTFTWHEFDCAASNLAETLAGLG-VGPGDRVAVWHGDCAAIHVL
                                             :  .    .  *.  *           : .   : .     

Rv2948c|M.tuberculosis_H37Rv        LLACLARGVMAFLANPELHRDDHALAARNTEPALVVTSDALRDRFQPSRV
Mb2972c|M.bovis_AF2122/97           LLACLARGVMAFLANPELHRDDHALAARNTEPALVVTSDALRDRFQPSRV
MLBr_00134|M.leprae_Br4923          LLACLARGIMAFLANPELHRDDYAFPERDTAAALVITNGSLRDRFQSSNV
MMAR_1761|M.marinum_M               LLACLARGILAFLANPELHRDDHAFQERDTQAALVITSGPLCDRFAPSTV
MUL_2004|M.ulcerans_Agy99           LLACLARGILAFLANPELHRDDQAFQERDTQAALVITSGPLCDRFAPSTV
Mflv_5271|M.gilvum_PYR-GCK          TFAAASLGAATAIVNCRLAPDELDYVLNDSGAKLLIVGEEFTGSIDKIRD
MAB_4569c|M.abscessus_ATCC_199      WLAINELGAIAIPVNFRMTPPEVAFLVENSGAKVAITETVLAPVAAAVRQ
MSMEG_5633|M.smegmatis_MC2_155      MFGVWAAECVYVPINYKLHPREMADILADSGAALVFASPKIAPGLFEVTD
Mvan_4968|M.vanbaalenii_PYR-1       MFAIWAAECVFVPLNYKLHVREMEQILSDAGAARVFTSPKIGAELAPVAS
TH_3448|M.thermoresistible__bu      VFGTAAAGVPIAPLNYRLTDDQVNDAVRRLTPVMVVAGTDAAHRVPPGDG
MAV_2995|M.avium_104                FVAIERRGAVIVGIGERAGAREAGAILRNAQPKILLSDQPRSKPAAEVAG
                                     ..           . .    :         .   .              

Rv2948c|M.tuberculosis_H37Rv        AEAAELMSEAARVAPGG-----------------YEPMGGDALAYATYTS
Mb2972c|M.bovis_AF2122/97           AEAAELMSEAARVAPGG-----------------YEPMGGDALAYATYTS
MLBr_00134|M.leprae_Br4923          VEPAELLSDATRVEPSD-----------------YEPVSGDAYAFATYTS
MMAR_1761|M.marinum_M               VDAADLFSEAARVGPAD-----------------YEILGGDAAAYATYTS
MUL_2004|M.ulcerans_Agy99           VDAADLFSEAARAGPAD-----------------YEILGGDAAAYATYTS
Mflv_5271|M.gilvum_PYR-GCK          KLGRVEHVISVKPDGDD---EYEAMLEASSPVDRADDVEPGDVCIIMYSS
MAB_4569c|M.abscessus_ATCC_199      QAPALETVIVAGSASENGVLGYEEVIAEPGEPHAEVDLPGDTPALIMYTS
MSMEG_5633|M.smegmatis_MC2_155      VPVEVVGTDAYTQRFES------------EPVPAP-LTDPAELAWLFYTS
Mvan_4968|M.vanbaalenii_PYR-1       TGIEIIGAAEYESRCAA------------MPSPAPRDTDPASPAWLFYTS
TH_3448|M.thermoresistible__bu      VVVRRTDDVVRSAAAGA-------------AGAELPFVDPDDPAVLLFTS
MAV_2995|M.avium_104                ELRIPALVLTQPLDTEP------------RAFDRDCQLGPDDVFLINSTS
                                                                                    :*

Rv2948c|M.tuberculosis_H37Rv        GTTGPPKAAIHRHADPLTFVDAMCRKALRLTPEDTGLCSARMYFAYGLGN
Mb2972c|M.bovis_AF2122/97           GTTGPPKAAIHRHADPLTFVDAMCRKALRLTPEDTGLCSARMYFAYGLGN
MLBr_00134|M.leprae_Br4923          GTTGKPKAAIHRHADPFTFVDAMCRKALRLTPQDIGLCSARMYFAYGLGN
MMAR_1761|M.marinum_M               GTTGPPKAAIHRHCDVFAFVEAMCRNALRLTPADIGLSSARMYFAYGLGN
MUL_2004|M.ulcerans_Agy99           GTTGPPKAAIHRHCDVFAFVEAMCCNALRLTPADIGLSSARMYFAYGLGN
Mflv_5271|M.gilvum_PYR-GCK          GTTGRPKGVELTQANIIAHTVNAHEGFEFDE-GDKNMVSMPLFHVGGSSY
MAB_4569c|M.abscessus_ATCC_199      GTTGRPKGAVLTHLNLSGQAMTYLLSTTVDLNSDVGFIGVPMFHIAGVGN
MSMEG_5633|M.smegmatis_MC2_155      GTTGKSKGAMLSHRNLMAMTVAHLADFDAPDEFCSLVHGAPMSHGSG-LY
Mvan_4968|M.vanbaalenii_PYR-1       GTTGRSKGAMLSHRNLMAMTVSHLADFDCPDENSSLIHGAPMSHGSG-LY
TH_3448|M.thermoresistible__bu      GTTGAPKAAVLRHRHLTSYIVGTVEFFNADE-DEAILVSVPNYHIAGISS
MAV_2995|M.avium_104                GTTGLPKCVVHTQNRWYYFHQKAVAN-GMLTPDDVFLPVIPTPFGFGIWT
                                    **** .* .   :                       .      .  *   

Rv2948c|M.tuberculosis_H37Rv        SVWFPLATGGSAVINSAPVTPEAAAILSARFGPSVLYGVPNFFARVIDSC
Mb2972c|M.bovis_AF2122/97           SVWFPLATGGSAVINSAPVTPEAAAILSARFGPSVLYGVPNFFARVIDSC
MLBr_00134|M.leprae_Br4923          SVWFPLATGGSAVISSVPVSAESAAMLSTRFEPSVLYGVPSFFARVVGAC
MMAR_1761|M.marinum_M               SVWFPLATGSSAVVNPLPVGAEVAATLSARFEPSVLYGVPNFFARVVDAC
MUL_2004|M.ulcerans_Agy99           SVWFPLATGSSAVVNPLPVGAEVAATLSARFEPSVLYGVPNFFARVVDAC
Mflv_5271|M.gilvum_PYR-GCK          VQFGIHDGFPSVMT--RDVD-GMTLAGAILKGANRTFLVPAVLAKVLDAG
MAB_4569c|M.abscessus_ATCC_199      MITGLLLGLPTVIHPLGAFDPGALLDVLESEGVTGIFLVPAQWQAVCAAQ
MSMEG_5633|M.smegmatis_MC2_155      IPPYVLRGARQVIPESGAFEPDEFLDLCDHHPGCSAFLAPTMVQRLIQTG
Mvan_4968|M.vanbaalenii_PYR-1       VPPYVSRGARQVVPASGTFDPDEFLDLCESHPGCSAFLAPTMVARLVQTG
TH_3448|M.thermoresistible__bu      VLSSVYAGRRMVQLP--AFSPEGWVELAAAERITQAMVVPTMLGRILDVL
MAV_2995|M.avium_104                SHTTPIHLG-ATAVILDRFTPAATCEAIARHGVTVLCCVSTQLTMLMADP
                                               .      .                   ..     :    

Rv2948c|M.tuberculosis_H37Rv        SPDS--FRSLRCVVSAGEALELGLAERLMEFFGGIPILDGIGSTEVGQTF
Mb2972c|M.bovis_AF2122/97           SPDS--FRSLRCVVSAGEALELGLAERLMEFFGGIPILDGIGSTEVGQTF
MLBr_00134|M.leprae_Br4923          SPDS--FRSLRCVVTAGEALEPALAERLVEFFGGIPILDGIGSSEVGQTF
MMAR_1761|M.marinum_M               SADS--FRSVRCVVSAGEALEVGLAERLTEFFGGIPILDGVGSTEVGQTF
MUL_2004|M.ulcerans_Agy99           SADS--FRSVRCVVSAGEALEVGLAERLTEFFGGIPILDGVGSTEVGQTF
Mflv_5271|M.gilvum_PYR-GCK          EDAVKLFGSLKTFAYGASPMPLPLLRQALEAWPNTDFMQAYGLTELCGVI
MAB_4569c|M.abscessus_ATCC_199      QANPRKVR-LKTLSWGAAPATDVLLRTMSETFPDARILAAFGQTEMSPVT
MSMEG_5633|M.smegmatis_MC2_155      RPRP---ANLRTVVYGGGPMYVDSLKKALAAYG-QIFVQLYGQGEAPMTI
Mvan_4968|M.vanbaalenii_PYR-1       RACP---ANLRTIVYGGGPMYVDSLKKAMAAFG-PVFVQLYGQGEAPMTI
TH_3448|M.thermoresistible__bu      EERGTELPALRTLSYGGGRMPVQTVERAMRLLPHVDFVNAYGLTETSSTI
MAV_2995|M.avium_104                ASRRHDLSSLRIVYTGGEALPYRPAAEFEELTG-ATILQFYGSNETGMLS
                                             :: .  ..                   ::   *  *     

Rv2948c|M.tuberculosis_H37Rv        VSNRVD-------------EWRLGTLGRVLPPYEIRVVAPDGTT-AGPGV
Mb2972c|M.bovis_AF2122/97           VSNRVD-------------EWRLGTLGRVLPPYEIRVVAPDGTT-AGPGV
MLBr_00134|M.leprae_Br4923          VSNSVD-------------DWRVGTLGKVLPPYEIRVVAPDGAT-AGSGI
MMAR_1761|M.marinum_M               VSNTVD-------------EWRPGSLGKVLPPYQIRVVAPDGAA-AGPGV
MUL_2004|M.ulcerans_Agy99           VSNTVD-------------EWRPGSLGKVLPPYQIRVVAPDGAA-AGPGG
Mflv_5271|M.gilvum_PYR-GCK          SHLLPEAHRDPGR------EERLSSAGTLVPNAELRVVDPDTLKDVPTGE
MAB_4569c|M.abscessus_ATCC_199      CMLMGDDAIR-----------KMGSVGRVIPTVSARVVD-DNMNDVPVGE
MSMEG_5633|M.smegmatis_MC2_155      TGLRRDDHLDAD-------DATLGSVGYPRSGVQVAVLRSDGTP-ADIGE
Mvan_4968|M.vanbaalenii_PYR-1       TGLRRRDHLDAP-------DAVLGSVGYARSGVDVAVLGPDGAP-VAVGE
TH_3448|M.thermoresistible__bu      AVLGPEDHRAAFGSDDPAVRARLGSVGRPLPSVEVEIRDHTGAP-VPPGQ
MAV_2995|M.avium_104                ATTVHDPR-----------DRRLGTAGRVVP--EMAVRLFDGDTDVTATG
                                                           .: *   .  .  :        .    

Rv2948c|M.tuberculosis_H37Rv        EGDLWVRGPAIAKGYWNRPDS---PVANEGWLDTRDRVCIDSDGWVTYRC
Mb2972c|M.bovis_AF2122/97           EGDLWVRGPAIAKGYWNRPDS---PVANEGWLDTRDRVCIDSDGWVTYRC
MLBr_00134|M.leprae_Br4923          EGNLWVRGPSIAQSYWNRPDS---LLENGDWLNTRDRVRIDGDGWVTYGC
MMAR_1761|M.marinum_M               EGDLWVRGPSIAESYWNWPEP---LLTDEGWLDTRDRVCIDDDGWVTYAC
MUL_2004|M.ulcerans_Agy99           EGDLWVRGPSIAESYWNWPEP---LLTDEGWLDTRDRVCIDDDGWVTYAC
Mflv_5271|M.gilvum_PYR-GCK          QGELWFRSPQLMKGYHNKPEATAESITEDGWFRTGDVGRVDDGGYIFVED
MAB_4569c|M.abscessus_ATCC_199      VGEIVYRAPTLMQGYWNNPEATADAFAG-GWFHSGDLVRQDEDGFVWVVD
MSMEG_5633|M.smegmatis_MC2_155      IGEIVCRGDVVMSGYWNNPEATAATLKD-GWLHTGDMGSFDARGHLTLRD
Mvan_4968|M.vanbaalenii_PYR-1       IGEIVCRGDVVMSGYWQNPEATEAALQH-GWLRTGDMGSFDAHGFLTLRD
TH_3448|M.thermoresistible__bu      FGEVYVRGEQVAGEYTSHS-----ALDAEGWYPTRDRGRLDDAGYLFLDG
MAV_2995|M.avium_104                RGQPACRGPATSLGYLGGTDHD-KLFTRDGWMRMGDICEIDADGYLRVTG
                                     *:   *.      *   .      .   .*    *    *  * :    

Rv2948c|M.tuberculosis_H37Rv        RADDTEVIGGVNVDPREVERLIIEDEAVAEAAVVAVRESTGASTLQAFLV
Mb2972c|M.bovis_AF2122/97           RADDTEVIGGVNVDPREVERLIIEDEAVAEAAVVAVRESTGASTLQAFLV
MLBr_00134|M.leprae_Br4923          RADDTEIVGGVNINPREVERLIIEADAVAEAAVVGVREFTGASTLQAFLV
MMAR_1761|M.marinum_M               RADDTEIVGAVNINPREIERLIVEEDAVAEVAVVGVKEATGASTLQAFLV
MUL_2004|M.ulcerans_Agy99           RADDTEIVGAVNINPREIERLIVEEDAVAEVAVVGVKEATGASTLQAFLV
Mflv_5271|M.gilvum_PYR-GCK          RLKDMIISGGENIYSIEVERVLAEHDAVVEVAVIGVPDDKWGEVVKAVVV
MAB_4569c|M.abscessus_ATCC_199      RKKDMIISGGENIYCAEVENALAEHEQIAEVAVIGRPHEKWGEVPVAVAA
MSMEG_5633|M.smegmatis_MC2_155      RSKDVVISGGSNIYPREVEEVLLEHPDVVEAGVVGAPDAEWGEIVVAFVV
Mvan_4968|M.vanbaalenii_PYR-1       RSKDVVISGGSNIYPREVEEVLLEHPGVVEAGVVGAPDEEWGEVVVAFIV
TH_3448|M.thermoresistible__bu      RADDVIVRGGENISPGEIEDVLVEHPAVAEAAAVGVADREWGERVEAVVV
MAV_2995|M.avium_104                RTSDFILRGGKNISASQVEDAAMTHPAVAIAAAVAMPDPVFGEKVCLYAE
                                    * .*  : *. *:   ::*        :. ...:.  .   ..       

Rv2948c|M.tuberculosis_H37Rv        ATSGATI-----DGSVMRDLHRGLLNR-LSAFKVPHRFAVVDRLPRTPNG
Mb2972c|M.bovis_AF2122/97           ATSGATI-----DGSVMRDLHRGLLNR-LSAFKVPHRFAVVDRLPRTPNG
MLBr_00134|M.leprae_Br4923          PAVGAFI-----DESVMRDVHRRLLTQ-LTAFKVPHRFAIIERLPRSTNG
MMAR_1761|M.marinum_M               PASAEGI-----DGSVMRDIHRRLLTR-LSAFKVPHRFAVVERLPRTANG
MUL_2004|M.ulcerans_Agy99           PASAEGI-----DGSVMRHIHRRLLTR-LSAFKVPHRFAVVERLPRTANG
Mflv_5271|M.gilvum_PYR-GCK          IE-G---------ETSESELIAFARER-LAAYKCPKSVDITDELPRKPTG
MAB_4569c|M.abscessus_ATCC_199      IH-GA--------ALTLAELDGFLTAR-LARYKHPKDLVIVDALPRNPSG
MSMEG_5633|M.smegmatis_MC2_155      TN-GT--------PVDAAALDAHLLER-IARFKRPKRYEFIDALPKNSYG
Mvan_4968|M.vanbaalenii_PYR-1       G------------AASAADLDAHLLER-IARFKRPKRYEFVDELPKNSYG
TH_3448|M.thermoresistible__bu      AAPGA--------QVVESELQDWVRQR-LRSTRVPARIHQWDELPYNETG
MAV_2995|M.avium_104                LAGPATDPATDPATLDLADLTEHLLAQGFSKELLPERLVVVDELPRSSGG
                                                       :      : :     *      : ** .  *

Rv2948c|M.tuberculosis_H37Rv        KLVRGALRKQSPTKPIWELSLTEPGSGVRAQRDDLSASN--MTIAGGNDG
Mb2972c|M.bovis_AF2122/97           KLVRGALRKQSPTKPIWELSLTEPGSGVRAQRDDLSASN--MTIAGGNDG
MLBr_00134|M.leprae_Br4923          KLLRNVLRAQSPTKPIWELSLTESQSATKAQLDGRPASNAHAQAAVGHAA
MMAR_1761|M.marinum_M               KLLRSALRGQTPAKPIWELASAEHRSGAPGQLDDQSASA-----LVSGSR
MUL_2004|M.ulcerans_Agy99           KLLRSALRGQTPAKPIWELASAEHRSDAPGQLDDQSASA-----LVSGSR
Mflv_5271|M.gilvum_PYR-GCK          KILKKELRKPHWDGRDRATV------------------------------
MAB_4569c|M.abscessus_ATCC_199      KVLKTELRQRFGIAD-----------------------------------
MSMEG_5633|M.smegmatis_MC2_155      KVLKRELRERVTG-------------------------------------
Mvan_4968|M.vanbaalenii_PYR-1       KVLKRELRARLG--------------------------------------
TH_3448|M.thermoresistible__bu      KLLRRVLRDELNARTPTEQVAG----------------------------
MAV_2995|M.avium_104                KVAKGRLREDIRARMEAGDERS----------------------------
                                    *: :  **                                          

Rv2948c|M.tuberculosis_H37Rv        GATLRERLVALRQERQRLVVDAVCAEAAKMLGEPDPWSVDQDLAFSELGF
Mb2972c|M.bovis_AF2122/97           GATLRERLVALRQERQRLVVDAVCAEAAKMLGEPDPWSVDQDLAFSELGF
MLBr_00134|M.leprae_Br4923          GATLKQRLSALQQERERLVVEAVCAEAVKMLGESDPGLINRDLAFSDLGF
MMAR_1761|M.marinum_M               EVSLKERLAALQQERHRLVLDAVCGETAKMLGEPDPRSVNRDLAFSELGF
MUL_2004|M.ulcerans_Agy99           EVSLKERLAALQQERHRLVLDAVCGETAKMLGEPDPRSVNRDLAFSELGF
Mflv_5271|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_4569c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5633|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_4968|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_3448|M.thermoresistible__bu      --------------------------------------------------
MAV_2995|M.avium_104                --------------------------------------------------
                                                                                      

Rv2948c|M.tuberculosis_H37Rv        DSQMTVTLCKRLAAVTGLRLPETVGWDYGSISGLAQYLEAELAGGHGRLK
Mb2972c|M.bovis_AF2122/97           DSQMTVTLCKRLAAVTGLRLPETVGWDYGSISGLAQYLEAELAGGHGRLK
MLBr_00134|M.leprae_Br4923          DSQMTVTLCNRLAVVTGLRLPETVGWDYGSISGLSRYLEAELSGVRSRPE
MMAR_1761|M.marinum_M               DSQMTVELCHRLAAATGLRVPETVGWDYGSISGLAQYLEAELSGADRR-V
MUL_2004|M.ulcerans_Agy99           DSQMTVELCHRLAAATGLRVPETVGWDYGSISGLAQYLEAELSGADRR-V
Mflv_5271|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_4569c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5633|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_4968|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_3448|M.thermoresistible__bu      --------------------------------------------------
MAV_2995|M.avium_104                --------------------------------------------------
                                                                                      

Rv2948c|M.tuberculosis_H37Rv        SAGPVNSGATGLWAIEEQLNKVEELVAVIADGEKQRVADRLRALLGTIAG
Mb2972c|M.bovis_AF2122/97           SAGPVNSGATGLWAIEEQLNKVEELVAVIADGEKQRVADRLRALLGTIAG
MLBr_00134|M.leprae_Br4923          TPLSANSGAKGLSPIDEELKKVEEMVVAIGASEKQRVADRLRALLGIIVD
MMAR_1761|M.marinum_M               TPQSARSGARALPLIEAQLNKVEELTAAIADGEKPRVAERLRALLGTITE
MUL_2004|M.ulcerans_Agy99           TPQSARSGARALPLIEAQLNKVEELTAAIADGEKPRVAERLRALLGTITE
Mflv_5271|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_4569c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_5633|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_4968|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_3448|M.thermoresistible__bu      --------------------------------------------------
MAV_2995|M.avium_104                --------------------------------------------------
                                                                                      

Rv2948c|M.tuberculosis_H37Rv        SEAGLGKLIQAASTPDEIFQLIDSELGK-
Mb2972c|M.bovis_AF2122/97           SEAGLGKLIQAASTPDEIFQLIDSELGK-
MLBr_00134|M.leprae_Br4923          GEAGLSKRIQAASTPDEIFQLIDSELCE-
MMAR_1761|M.marinum_M               GQEHWGQRIAAASTPDEIFQLIDSEFGES
MUL_2004|M.ulcerans_Agy99           GQEHWGQRIAAASTPDEIFQLIDSEFGES
Mflv_5271|M.gilvum_PYR-GCK          -----------------------------
MAB_4569c|M.abscessus_ATCC_199      -----------------------------
MSMEG_5633|M.smegmatis_MC2_155      -----------------------------
Mvan_4968|M.vanbaalenii_PYR-1       -----------------------------
TH_3448|M.thermoresistible__bu      -----------------------------
MAV_2995|M.avium_104                -----------------------------