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SFVVAAPEVVVAAASDLAGIGSAIGAANAAAAVPTMGVLAAGADEVSAAVADLFGAHAQAYQALSAQAAL FHEQFVHAMTAGAGAYAGAEAADAAALDVLNGPFQALFGRPLIGDGANGAPGQPGGPGGLLYGNGGNGGN GGIGQPGGAGGDAGLIGNGGNGGIGGPGATGLAGGAGGVGGLLFGDGGNGGAGGLGTGPVGATGGIGGPG GAAVGLFGHGGAGGAGGLGKAGFAGGAGGTGGTGGLLYGNGGNGGNVPSGAADGGAGGDARLIGNGGDGG SVGAAPTGIGNGGNGGNGGWLYGDGGSGGSTLQGFSDGGTGGNAGMFGDGGNGGFSFFDGNGGDGGTGGT LIGNGGDGGNSVQTDGFLRGHGGDGGNAVGLIGNGGAGGAGSAGTGVFAPGGGSGGNGGNGALLVGNGGA GGSGGPTQIPSVAVPVTGAGGTGGNGGTAGLIGNGGNGGAAGVSGDGTPGTGGNGGYAQLIGDGGDGGPG DSGGPGGSGGTGGTLAGQNGSPGG*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. tuberculosis H37Rv | Rv1840c | PE_PGRS34 | - | 100% (515) | PE-PGRS FAMILY PROTEIN |
M. tuberculosis H37Rv | Rv2162c | PE_PGRS38 | e-148 | 55.90% (542) | PE-PGRS family protein |
M. tuberculosis H37Rv | Rv1396c | PE_PGRS25 | e-145 | 54.69% (576) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1871c | PE_PGRS34 | 0.0 | 87.96% (515) | PE-PGRS family protein |
M. gilvum PYR-GCK | Mflv_5091 | - | 1e-83 | 44.19% (525) | triple helix repeat-containing collagen |
M. leprae Br4923 | MLBr_01183 | - | 2e-13 | 37.50% (96) | hypothetical protein MLBr_01183 |
M. abscessus ATCC 19977 | MAB_4284c | - | 6e-38 | 35.15% (404) | hypothetical protein MAB_4284c |
M. marinum M | MMAR_2709 | - | 1e-173 | 61.75% (536) | PE-PGRS family protein, PE_PGRS34_1 |
M. avium 104 | MAV_4827 | - | 7e-20 | 41.85% (184) | hypothetical protein MAV_4827 |
M. smegmatis MC2 155 | MSMEG_0868 | - | 2e-71 | 38.49% (569) | hypothetical protein MSMEG_0868 |
M. thermoresistible (build 8) | TH_4332 | - | 2e-40 | 36.26% (353) | PUTATIVE - |
M. ulcerans Agy99 | MUL_3056 | - | 0.0 | 63.57% (549) | PE-PGRS family protein |
M. vanbaalenii PYR-1 | Mvan_1264 | - | 9e-84 | 41.32% (576) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment Rv1840c|M.tuberculosis_H37Rv -------------------------------------------------- Mb1871c|M.bovis_AF2122/97 -------------------------------------------------- MUL_3056|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2709|M.marinum_M -------------------------------------------------- TH_4332|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Rv1840c|M.tuberculosis_H37Rv -------------------------------------------------- Mb1871c|M.bovis_AF2122/97 -------------------------------------------------- MUL_3056|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2709|M.marinum_M -------------------------------------------------- TH_4332|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP-- MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Rv1840c|M.tuberculosis_H37Rv -------------------------------------------------- Mb1871c|M.bovis_AF2122/97 -------------------------------------------------- MUL_3056|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2709|M.marinum_M -------------------------------------------------- TH_4332|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Rv1840c|M.tuberculosis_H37Rv -------------------------------------------------- Mb1871c|M.bovis_AF2122/97 -------------------------------------------------- MUL_3056|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2709|M.marinum_M -------------------------------------------------- TH_4332|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Rv1840c|M.tuberculosis_H37Rv -------------------------------------------------- Mb1871c|M.bovis_AF2122/97 -------------------------------------------------- MUL_3056|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2709|M.marinum_M -------------------------------------------------- TH_4332|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ------------------------------------------MSIIDFIL MAV_4827|M.avium_104 ------------------------MNIVLGVSMAPSSIQMVVLEGEYADG Rv1840c|M.tuberculosis_H37Rv ---------MSFVVAAPEVVVAAASDLAGIGSAIGAANAAAAVPTMG--- Mb1871c|M.bovis_AF2122/97 ---------MSFVVAAPEVVVAAASDLAGIGSAIGAANAAAAVPTMG--- MUL_3056|M.ulcerans_Agy99 ---------MSFVVAAPDAVTAAVQDLASIGSAINVANAAAATPTTG--- MMAR_2709|M.marinum_M ---------MSFVVAAPEMVQAAASDIASIGSTINMANVAATAPTTA--- TH_4332|M.thermoresistible__bu ---------MPFITSGAAFVGGAAMLLAGPGGVSALEAAGSAPR------ Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG MLBr_01183|M.leprae_Br4923 --------MPLFLNAEPQALTAAANTLEGLSAATVASNAAAAQLTTE--- MAB_4284c|M.abscessus_ATCC_199 NLFRDPVEAASYVADPEAALANAGLSAVSAAQVGAVMPVVAESVASNYG- MAV_4827|M.avium_104 ATVEEDAIDVTGADDAATASAPDRVISAILGTREGAADAGLQLSSIG--- . Rv1840c|M.tuberculosis_H37Rv -----------------------------VLAAGADEVSAAVADLFGAHA Mb1871c|M.bovis_AF2122/97 -----------------------------VLAAGADEVSAAVADLFGAHA MUL_3056|M.ulcerans_Agy99 -----------------------------ALAAAADEVSAAVAALFDGHA MMAR_2709|M.marinum_M -----------------------------VLAAGADEVSAVIAALFAAHG TH_4332|M.thermoresistible__bu --------------------------------------TVEYEYSLVACD Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG MLBr_01183|M.leprae_Br4923 -----------------------------IAPPAADDVSILLAHFFSGHG MAB_4284c|M.abscessus_ATCC_199 -----------------------YQSQWVNTGNPIHDLSGNLQNYYAAQP MAV_4827|M.avium_104 -------------------------VTWTDQLEAAALRDALAARRIDNVM Rv1840c|M.tuberculosis_H37Rv QAYQALSAQAALFHEQFVHAMTAGAGAYAGAEAADA-------------- Mb1871c|M.bovis_AF2122/97 QAYQALSAQAALFHEQFVHAMTAGAGAYAGAEAADA-------------- MUL_3056|M.ulcerans_Agy99 QAYQLIGAQAAEFHERFVRAMAAGAASYATAEAANAS----------PLQ MMAR_2709|M.marinum_M QAYQTLSAQAAQFHDQFVAAMTSAAGAYSGAEAANVS----------PLQ TH_4332|M.thermoresistible__bu STLPLMCEAGDSVGGLGGASHDRSAFSASALGMAS--------------- Mflv_5091|M.gilvum_PYR-GCK VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------A Mvan_1264|M.vanbaalenii_PYR-1 VTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------A MSMEG_0868|M.smegmatis_MC2_155 GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT MLBr_01183|M.leprae_Br4923 RQYQAHASQGATNHQDLIQSLLTSSSAYAGTETAN--------------- MAB_4284c|M.abscessus_ATCC_199 DGPSILSPSLLSPRDNDFLSHNDTDFASHNPIASGNQ--------VMSPS MAV_4827|M.avium_104 LVSAFLAAAALAQNVGGAMGYERTAVLLVEPDTAT--------------L . . Rv1840c|M.tuberculosis_H37Rv AALDVLNGPFQALFGRPLIGDGANGAPGQPGGPGG--------------- Mb1871c|M.bovis_AF2122/97 AALDVLNGPFQALFGRPLIGDGANGAPGQPGGPGG--------------- MUL_3056|M.ulcerans_Agy99 AALDAVNAPAQALLGRPLIGDGADGAPGQPGGAGG--------------- MMAR_2709|M.marinum_M SLLDAANGETMAMLGRPLIGNGADGAPGQAGADGG--------------- TH_4332|M.thermoresistible__bu FGPDWNPGGAFLG------------------------------------- Mflv_5091|M.gilvum_PYR-GCK VGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG---------------- Mvan_1264|M.vanbaalenii_PYR-1 VGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG---------------- MSMEG_0868|M.smegmatis_MC2_155 VGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGH MLBr_01183|M.leprae_Br4923 --HDSL-------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 GNVDSFNRGPLLDLSFGDLQFGNRDTTAIGDGAVAVG------------- MAV_4827|M.avium_104 AVVETSDGSIPDVYKQQIRAESYGDAAGQLSAMVAG-------------- Rv1840c|M.tuberculosis_H37Rv ---------------LLYGNGGNGGNG--------------GIGQPGGAG Mb1871c|M.bovis_AF2122/97 ---------------LLYGNGGNGGNG--------------GIGQPGGAG MUL_3056|M.ulcerans_Agy99 ---------------LLYGNGGSGGNG--------------GIGQAGGAG MMAR_2709|M.marinum_M ---------------LLFGNGGNGGSG--------------LAGQAGGVG TH_4332|M.thermoresistible__bu ---------------LIGPGGLLIGDG---------------LNGTDAYI Mflv_5091|M.gilvum_PYR-GCK AVGAAGAAG------TVGTAGATGGTG---------------TGANGGAG Mvan_1264|M.vanbaalenii_PYR-1 AIGTAGVAG------AAGTAGATGGTG---------------VGGNGGAG MSMEG_0868|M.smegmatis_MC2_155 AIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHS MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ---------------GSNSGPIASGQG--------------STAVNGDVR MAV_4827|M.avium_104 ----------LEKLESLPGGLLLVGSGVDVAPLKQVLQTTTFLDVSVAEE Rv1840c|M.tuberculosis_H37Rv GDAGLIGNGGNG-----------------GIGGPGATGLAGGAGGVGGLL Mb1871c|M.bovis_AF2122/97 GDAGLIGNGGNG-----------------GIGGPGATGLAGGAG------ MUL_3056|M.ulcerans_Agy99 GDAGLIGNGGSG-----------------GIGGPDSTGLPGGAGGAGGWL MMAR_2709|M.marinum_M GAAGLIGNGGNG-----------------GAGGAGSNGLAGGSGGAGGWL TH_4332|M.thermoresistible__bu DENGVFHEATRG----------------------GNGGLLWGNGGKGGN- Mflv_5091|M.gilvum_PYR-GCK GVGGVGGTGAAG--------------AAGGAGGLGETGTTGGAGGVGGQ- Mvan_1264|M.vanbaalenii_PYR-1 QAGGIGGTGAAG--------------AAGQAGTAGETGVTGGVGGIGGQ- MSMEG_0868|M.smegmatis_MC2_155 TGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEIY MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 DSNIINADHGSNVG---------VDQSQTRVGGDYTNVSGHGSADIDKSV MAV_4827|M.avium_104 PETALARGAALAAAN---------APLFASSTAALAYAQDPGTGAVDQYS Rv1840c|M.tuberculosis_H37Rv FGDGGNGGAGGLGTGPVGATGGIGGPGGAAVGLFGHGGAGGA-------- Mb1871c|M.bovis_AF2122/97 -------------------------------------------------- MUL_3056|M.ulcerans_Agy99 LGDGGNGGIGGAGTG-IGGAGGSGGQGGAAAWLFGSGGTGGA-------- MMAR_2709|M.marinum_M IGNGGNGGVGGIGSAAVGN-GGSGGAGGAAVGLFGNGGIGG--------- TH_4332|M.thermoresistible__bu -GLDAGLYTVPDPDN-PGSTIQMYFEASDG-------------------- Mflv_5091|M.gilvum_PYR-GCK -GTAGGTGGVGGIGG-AGSTGAVGGVGGKG----IQGGQG---------- Mvan_1264|M.vanbaalenii_PYR-1 -GTEGGTGGVGGVGG-VGATGGAGGVGGKG----IQGGQG---------- MSMEG_0868|M.smegmatis_MC2_155 SGADGEATGISAGGD-GGSATGADSLGGRGGTSWVQAGYGPTTGGKASGT MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 TVVDDHSQRNTTNINDSFNTDRSTNIGSGNTTNTEIGSHNQAN------- MAV_4827|M.avium_104 LPDYLYVPVDPEPGDDELAYSAVGEEDAESPTVVIEKLFLPEDSEPRRRP Rv1840c|M.tuberculosis_H37Rv --GGLGKAGFAGGAGGTGGTGGLLYG------------------------ Mb1871c|M.bovis_AF2122/97 ---GLGKAGFAGGAGGTGGTGGLLYG------------------------ MUL_3056|M.ulcerans_Agy99 --GGFGNSG-TGGPGGAGGTGGLLIG------------------------ MMAR_2709|M.marinum_M --AGGGAEGLNGGAGGVGGIGGKLYG------------------------ TH_4332|M.thermoresistible__bu ---------ADGGRGG---------------------------------- Mflv_5091|M.gilvum_PYR-GCK ---LQGGKGGDGGAGGKGGDADSMGS------------------AGATGG Mvan_1264|M.vanbaalenii_PYR-1 ---LQGGQGGDGGTGGTGGDATSMGE------------------AGATGG MSMEG_0868|M.smegmatis_MC2_155 AKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANGA MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ----IGTSTSAGGSAAVGGNAGLAGN----------------------AG MAV_4827|M.avium_104 VLLVGSGLAVVGISAVLALEIALAIG----------------------IR Rv1840c|M.tuberculosis_H37Rv NGGNGGNVPSGAAD-------GGAGGDAR-LIGNGGDGGS---------- Mb1871c|M.bovis_AF2122/97 NGGNGGNVPSGAAD-------GGAGGDAR-LIGNGGDGGS---------- MUL_3056|M.ulcerans_Agy99 NGGNGGYDIQGGAF-------GGDGGNAR-LIGNGGDGGV---------- MMAR_2709|M.marinum_M DGGAGGIGGMGAADPSAAGGAGGAGGSAVGWFGDGGAGGAG--------- TH_4332|M.thermoresistible__bu -----------FLFG---------------NGGDGGNGGN---------- Mflv_5091|M.gilvum_PYR-GCK KGGNGGNGGRGGLFG---------------KGGNAGNGAD---------- Mvan_1264|M.vanbaalenii_PYR-1 KGGNGGNGGRGSLFG---------------RGGNAGNGGN---------- MSMEG_0868|M.smegmatis_MC2_155 VGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 LAGNAGLAGNAGLAG------NAGLAGNAGLAGNAGLAGN---------- MAV_4827|M.avium_104 TTGTVALQPTPNQHLIVPTEQAPAPPPVQASAPQPKISVPEP-------- Rv1840c|M.tuberculosis_H37Rv --------VGAAPTGIGNGGNGGNGGWLYGDGGSGGST----LQGFS--- Mb1871c|M.bovis_AF2122/97 --------VGAAPTGIGNGGNGGNGGWLYGDGGSGGST----LQGFS--- MUL_3056|M.ulcerans_Agy99 --------EAGGPG--TTGGDGGNGGWLLGNGGNGAAD----GGGAGSAA MMAR_2709|M.marinum_M ---GPVVPTAALGGLGGAGGAGGNGGQLWGDGGAGGLG----AFGQHG-- TH_4332|M.thermoresistible__bu -----------------VGGKNGADPVTATVAADKS-------------- Mflv_5091|M.gilvum_PYR-GCK ------------GGTGGAGGAGGTGG-TGGAGGTGG-------------- Mvan_1264|M.vanbaalenii_PYR-1 ------------GGTGGNGGNGGTGG-TGGNGGTGG-------------- MSMEG_0868|M.smegmatis_MC2_155 PAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKAN------ MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ------------AGLAGNAGLAGNAGLAGNAGLAGNAG------------ MAV_4827|M.avium_104 -VAAPKPLSPPVAAPLPAAPPPAAPPLPEAPPIPAAPPVVPVPVVVPPVP Rv1840c|M.tuberculosis_H37Rv --------------------DG--------GTGGNAGMFGDGGNGGFSFF Mb1871c|M.bovis_AF2122/97 --------------------DG--------GTGGNAGMFGDGGNGGFSFF MUL_3056|M.ulcerans_Agy99 GAGGNAGLIGNGGHGGLEHIDGTGGAGSIAGAGGDAGLFGSGGNGGFNGY MMAR_2709|M.marinum_M --------------------GGAG------GAGGNAGMVGNGGDGGTALG TH_4332|M.thermoresistible__bu ------------------------------------------------VA Mflv_5091|M.gilvum_PYR-GCK -------------------------------TGGTGGIGGAGSTGGTGGT Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------TGGTGGIGGAGSTGGTGGT MSMEG_0868|M.smegmatis_MC2_155 ----------------------GQHSTGQTDTGGNGGRGGDGGTFVNAGA MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------LAGNAGLAGNAGLAGNAGL MAV_4827|M.avium_104 VPVPVR--------------IPVPDPVSPPQLLAPPRLSVPQPVQPPVRV Rv1840c|M.tuberculosis_H37Rv DGNGGDGGTGGTLI--GNGGDGG-NSVQTDGFLRGHGGDGGNAVGLIGNG Mb1871c|M.bovis_AF2122/97 DGNGGDGGTGGTLI--GNGGDGG-NSVQTDGFLRGHGGDGGNAVGLIGNG MUL_3056|M.ulcerans_Agy99 QGVGGAGGAGGKLF--GDGGDGG-DCAESNGGI-GSGGRGGSAVGLIGNG MMAR_2709|M.marinum_M LAHGGDGGTGGTLI--GNGGAGG-GATMS------DAGDGGDAVGLIGSG TH_4332|M.thermoresistible__bu GGNGGNGGRGGLLF--GLGGNGGNGGWSTTSYLDARGGNGGNG----GLG Mflv_5091|M.gilvum_PYR-GCK GGTGGTGGTGGTG---GTGGTGGTGGTGGKGGTGGTGGAGGTG----GDG Mvan_1264|M.vanbaalenii_PYR-1 GGTGGTGGTGGTG---GTGGTGGTGGTGGKGGTGGTGGDGGTG----GTG MSMEG_0868|M.smegmatis_MC2_155 NGNGGAGGAGGVSE--GEGGTGGHGGDGGRGGDGALGGNGGTGGVGLGNG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 AGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAAVAGNAAVAG MAV_4827|M.avium_104 PQPPSPPQVGGTVPQ-SPPQHQTPPGEGTPPKPDGPGNYGGGHVPTPGAG Rv1840c|M.tuberculosis_H37Rv GAGGAGSA-------------GTGVFAPGGGSG---------------GN Mb1871c|M.bovis_AF2122/97 GAGGAGSA-------------GTGVFAPGGGSG---------------GN MUL_3056|M.ulcerans_Agy99 GAGGVG---------------GVGRNANAGGSG---------------GS MMAR_2709|M.marinum_M GAGGIG---------------GAALAGGTGGTG---------------GD TH_4332|M.thermoresistible__bu GVLRPGGLLSLLLP--------SGAASEPGGLF-------------TGGN Mflv_5091|M.gilvum_PYR-GCK GTGGTGGTGGTG---------GTGGTGGTGGAG-----------DGTGGT Mvan_1264|M.vanbaalenii_PYR-1 GTGGTGGTGGTG---------GTGGTGGTGGAG-----------DGLGGT MSMEG_0868|M.smegmatis_MC2_155 GKGGNGGNGGNGGTYVDPSHTGAGGNGGNGGAGRIRVNNGTATGTATGGN MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 NAAVAGNAAVGG-------VLNTGVSGAIGGSS--------------HVG MAV_4827|M.avium_104 GSGGSGG--------------GHVPTPGAGGSG---------------GS Rv1840c|M.tuberculosis_H37Rv GGNGALLVGNGGAGGSGG--------------------PTQIPSVAVPVT Mb1871c|M.bovis_AF2122/97 GGNGALLVGNGGAGGSGG--------------------PTQIPSVAVPVT MUL_3056|M.ulcerans_Agy99 GGNAAWLFGDGGAGGSGG--------------------SSD--------T MMAR_2709|M.marinum_M GGHGAKLLGNGGAGGAGG--------------------AAG------GGL TH_4332|M.thermoresistible__bu GGNGGLAIANHWVG-----------------------ITDGVPGPDDDAV Mflv_5091|M.gilvum_PYR-GCK GGTGG----TGGQGGQGGQGG-----------------TGGTGGQGG-LG Mvan_1264|M.vanbaalenii_PYR-1 GGTGG----TGGFGGQGGQGG-----------------TGGTGGQGG-LG MSMEG_0868|M.smegmatis_MC2_155 GGNGGNGDADGHRGGKGGDGGEALIRATVIGSNASGTATGGDGGNGGTLG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 GAINESLGGSGSVGGSTAVGG------------------GAHTGVGGGVS MAV_4827|M.avium_104 GGGHVPTPGTGGPGGTGG--------------------SGGGHVPTPGAG Rv1840c|M.tuberculosis_H37Rv GAGGTG-----------------------GNGGTAGLIGNGGNGGAAGVS Mb1871c|M.bovis_AF2122/97 GAGGTG-----------------------GNGGTAGLIGNGGNGGAAGVS MUL_3056|M.ulcerans_Agy99 AASGAG-----------------------GNGGTAALIGNGGAGGDAGVS MMAR_2709|M.marinum_M GNGGNG-----------------------GNGGEAALIGNGGAGGDAGTS TH_4332|M.thermoresistible__bu SSSAYG-----------------------GHGGHGAGPGSGGNGGSAVAN Mflv_5091|M.gilvum_PYR-GCK GGGGTG-----------------------GQGGTGGTGGQGGTGGTGGTG Mvan_1264|M.vanbaalenii_PYR-1 GVGGTG-----------------------GTGGTGGTGGQGGTGGTGGTG MSMEG_0868|M.smegmatis_MC2_155 ATNGTGGAATIVAYNVVQANPQASGTATDGHGGSGINGGHGGNGGQGTIE MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 TGVGVG-----------------------SHVGGGISESLGGSGSVGGST MAV_4827|M.avium_104 TPGGSG-------------------------GGHLPFPGAGSTPGGSGGG Rv1840c|M.tuberculosis_H37Rv GDG---------TPGTGGNGGYAQLIGDGGDGGPGDSGGPGGSGGTGGTL Mb1871c|M.bovis_AF2122/97 GDG---------TPGTGGNGGYAQLIGDGGDGGPGDSGGPGGSGGTGGTL MUL_3056|M.ulcerans_Agy99 FAG---------MAGPGGNGGDARLIGDGGDGG---RGAPGGAGGMGGSL MMAR_2709|M.marinum_M GSSR--------NFGDGGNGGDAQLIGNGGNGGRGGVNGTGGTGGNGGTV TH_4332|M.thermoresistible__bu SLG-------NAIAGNGGDAGRFVLIGPGGNGGNGGTGLXXXPRPRR--- Mflv_5091|M.gilvum_PYR-GCK GTG--------GTGGAGGDGGLGGLGGFGGSGGTGGQGGLGGPGGSTGGA Mvan_1264|M.vanbaalenii_PYR-1 GTG--------GTGGAGGDGGLGGLGGFGGVGGTGGQGGQGGPGGSTGGA MSMEG_0868|M.smegmatis_MC2_155 ANGPSAVASGIGAGGNGGDGIDGGLGGNGGDGVVNTTANAANPGSATGTA MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 AVG--------GGAHTGVGGGVSTGVGVGSHVGGGISESLGGSGSVGGST MAV_4827|M.avium_104 HLP---------TPGAGTPGG--GLGGFGGGHAPAPGGGLGGGGGHAPAP Rv1840c|M.tuberculosis_H37Rv AGQNG----------------------------------SPGG------- Mb1871c|M.bovis_AF2122/97 AGQNG----------------------------------SPGG------- MUL_3056|M.ulcerans_Agy99 FGQDG----------------------------------SNGA------- MMAR_2709|M.marinum_M AGANG----------------------------------TDGP------- TH_4332|M.thermoresistible__bu -----------------------------RRNHRRTRRRPNGRRPRPPPG Mflv_5091|M.gilvum_PYR-GCK GGAGG--QAGTAGKGGLFG----GSGSAGKAGATGAAGASGGKGAQGATG Mvan_1264|M.vanbaalenii_PYR-1 GGAGG--QAGVAGKGGLFG----GSGSAGTAGVTGASGASGGKGAQGATG MSMEG_0868|M.smegmatis_MC2_155 TGGDGGKATGTASQGGNGGPSWVQSGYGSTLGGNATGTATAGKGGEASNG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 AVGGG--------------------------------AHTGVGGGVNTGV MAV_4827|M.avium_104 GGGLG--------------------------------GFGGGHSGGGLGG Rv1840c|M.tuberculosis_H37Rv -------------------------------------------------- Mb1871c|M.bovis_AF2122/97 -------------------------------------------------- MUL_3056|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2709|M.marinum_M -------------------------------------------------- TH_4332|M.thermoresistible__bu R------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK AQGATG------AQGATG-ATGAAGKAGATGAAGAAGAAGSAG------- Mvan_1264|M.vanbaalenii_PYR-1 AQGATG------AQGATG-ATGASGAQGSAGSAGSAGVAGSAG------- MSMEG_0868|M.smegmatis_MC2_155 GVAGNGGNALVMAAGTTGVATGNTATGGDGGAATTAGATGGAGGFSNIAA MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 GVGSHVGGGISESLGGSGSVGGSTAVGGGAHTSAINDALGGSGSVGGSTA MAV_4827|M.avium_104 LGGGHK-------------------------------------------- Rv1840c|M.tuberculosis_H37Rv -------------------------------------------------- Mb1871c|M.bovis_AF2122/97 -------------------------------------------------- MUL_3056|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2709|M.marinum_M -------------------------------------------------- TH_4332|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK ----TTGAQGSAGTNGA-NGANGSQGAAGKAGATGTTGATG--------A Mvan_1264|M.vanbaalenii_PYR-1 ----TTGAQGSAGTNGA-NGANGSQGAAGKAGATGTTGATG--------A MSMEG_0868|M.smegmatis_MC2_155 IHGAITDSTAISGHGGAGNGGNGGKGADGWVQAYDPAGPVGSKIANSSAV MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 VGGGAHTSAINESMNSSINASHSSSMNESFGSSMGSHGAAGTGFEAQGHA MAV_4827|M.avium_104 -------------------------------------------------- Rv1840c|M.tuberculosis_H37Rv -------------------------------------------------- Mb1871c|M.bovis_AF2122/97 -------------------------------------------------- MUL_3056|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2709|M.marinum_M -------------------------------------------------- TH_4332|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK AGEDGDAGSGGSG-INGGAGGAGG-----------AGGEGGEGGDGGKGG Mvan_1264|M.vanbaalenii_PYR-1 AGDAGDPGSEAVD-INGGAGGAGG-----------AGGEGGEGGAGGAGG MSMEG_0868|M.smegmatis_MC2_155 AGNGGDGGVNGTGGASGGDGGNGGNTSVWKSGGQTADGEHNTGGNGGNGG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 QGHASETAHTTLPGAEHH-------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Rv1840c|M.tuberculosis_H37Rv -------------------------------------------------- Mb1871c|M.bovis_AF2122/97 -------------------------------------------------- MUL_3056|M.ulcerans_Agy99 -------------------------------------------------- MMAR_2709|M.marinum_M -------------------------------------------------- TH_4332|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK AGAE--------GGAGGGGGAGGSGAGGAG--GAGGSGGSGGSGGSGGSG Mvan_1264|M.vanbaalenii_PYR-1 DGSE--------GGAGGSGGAGGSGTGGAG--GAGGSGGSGGSGGAGGSG MSMEG_0868|M.smegmatis_MC2_155 DGSEPGPGGNGAGGAGGNGGTGGTTAGGSGNGGNGGNGGNGGADGTPGTA MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Rv1840c|M.tuberculosis_H37Rv -------- Mb1871c|M.bovis_AF2122/97 -------- MUL_3056|M.ulcerans_Agy99 -------- MMAR_2709|M.marinum_M -------- TH_4332|M.thermoresistible__bu -------- Mflv_5091|M.gilvum_PYR-GCK GAAGDSDD Mvan_1264|M.vanbaalenii_PYR-1 GAAGDSD- MSMEG_0868|M.smegmatis_MC2_155 GTTGANNP MLBr_01183|M.leprae_Br4923 -------- MAB_4284c|M.abscessus_ATCC_199 -------- MAV_4827|M.avium_104 --------