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M. thermoresistible (build 8) TH_4332 (-)

annotation: -
coordinates: 58645 - 59850
length: 402

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_4332--100% (402)-
M. thermoresistible (build 8)TH_3810-4e-2736.49% (285) PUTATIVE -
M. thermoresistible (build 8)TH_2853-3e-0731.47% (143) PUTATIVE -

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1121PE_PGRS222e-4236.72% (403) PE-PGRS family protein
M. gilvum PYR-GCKMflv_1516-2e-4538.70% (385) hypothetical protein Mflv_1516
M. tuberculosis H37RvRv1091PE_PGRS225e-4335.99% (414) PE-PGRS family protein
M. leprae Br4923MLBr_01556infB5e-0529.49% (156) translation initiation factor IF-2
M. abscessus ATCC 19977MAB_0321c-6e-1934.59% (292) hypothetical protein MAB_0321c
M. marinum MMMAR_4224-4e-4437.84% (407) PE-PGRS family protein
M. avium 104MAV_4827-2e-1234.15% (164) hypothetical protein MAV_4827
M. smegmatis MC2 155MSMEG_0868-6e-3737.33% (300) hypothetical protein MSMEG_0868
M. ulcerans Agy99MUL_4524-2e-4034.24% (403) PE-PGRS family protein
M. vanbaalenii PYR-1Mvan_5240-3e-4435.61% (424) PE-PGRS family protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb1121|M.bovis_AF2122/97            ------------MSFVIAAPEALVAVASDLAGIGSALAEAN-AAALAPTT
Rv1091|M.tuberculosis_H37Rv         ------------MSFVIAAPEALVAVASDLAGIGSALAEAN-AAALAPTT
MUL_4524|M.ulcerans_Agy99           ------------MSYLVAVPEMLASAALDLDNIGSTITAAN-AAAAAPTT
MMAR_4224|M.marinum_M               ------------MSFLVTAPEILAAAATDLDGIGAAIGAAN-AAAAAPTT
MSMEG_0868|M.smegmatis_MC2_155      MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
Mflv_1516|M.gilvum_PYR-GCK          -----------------------MARHANTSDRSAAIRRYLGAGITAGMA
Mvan_5240|M.vanbaalenii_PYR-1       -----------------------MARHAKKSDRSMAIRTYLTAGLTAGVT
MAB_0321c|M.abscessus_ATCC_199      --------------------------MANIISNG----------------
TH_4332|M.thermoresistible__bu      -------------------------MPFITSGAAFVGGAAMLLAGPGGVS
MAV_4827|M.avium_104                -MNIVLGVSMAPSSIQMVVLEGEYADGATVEEDAIDVTGADDAATASAPD
MLBr_01556|M.leprae_Br4923          -----MAGKARVHELAKELGVTSKEVLARLNEQGEFVKSASSTVEAPVAR
                                                                                      

Mb1121|M.bovis_AF2122/97            ALLAAG--------------------------ADEVSAAIAALFGAHGQA
Rv1091|M.tuberculosis_H37Rv         ALLAAG--------------------------ADEVSAAIAALFGAHGQA
MUL_4524|M.ulcerans_Agy99           AVLAAG--------------------------ADEISAAVAALFTGHAQA
MMAR_4224|M.marinum_M               AVLAAG--------------------------ADEISAAMASLFTAHAQA
MSMEG_0868|M.smegmatis_MC2_155      PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
Mflv_1516|M.gilvum_PYR-GCK          SAALAG-------------------------------VGTALLTDVDAST
Mvan_5240|M.vanbaalenii_PYR-1       GAALAG-------------------------------VGTLLLADGDVSG
MAB_0321c|M.abscessus_ATCC_199      -------------------------------------------PDGDAGA
TH_4332|M.thermoresistible__bu      ALEAAG-------------------------------SAPRTVEYEYSLV
MAV_4827|M.avium_104                RVISAILG-------------------------TREGAADAGLQLSSIGV
MLBr_01556|M.leprae_Br4923          RLRESFG-----------------------------GIKPAADKGAEQVA
                                                                                      

Mb1121|M.bovis_AF2122/97            YQTVSAQASAFHAQFVQALTGGGG-----------------------AYA
Rv1091|M.tuberculosis_H37Rv         YQTVSAQASAFHAQFVQALTGGGG-----------------------AYA
MUL_4524|M.ulcerans_Agy99           YQWLGAQAGAFHSQFIQALTGSGS-----------------------AYA
MMAR_4224|M.marinum_M               YQGLSVQVGAFHNQFVQALTGAGG-----------------------AYA
MSMEG_0868|M.smegmatis_MC2_155      SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
Mflv_1516|M.gilvum_PYR-GCK          STDPRVQLVSNEEELLWLTLDAGSD----------------------RAK
Mvan_5240|M.vanbaalenii_PYR-1       PAQIEVQLVSNEEDILWLSLNGGSD----------------------RRS
MAB_0321c|M.abscessus_ATCC_199      TGAQGSQGATG--------------------------------------A
TH_4332|M.thermoresistible__bu      ACDSTLPLMCEAGDSVGGLGGASHD-----------------------RS
MAV_4827|M.avium_104                TWTDQLEAAALRDALAARRIDNVMLVS------------------AFLAA
MLBr_01556|M.leprae_Br4923          TKAQAKRLGESLDQTLDRALDKAVAG----------------------NG
                                                                                      

Mb1121|M.bovis_AF2122/97            AAEAANVS------------------------------------------
Rv1091|M.tuberculosis_H37Rv         AAEAANVS------------------------------------------
MUL_4524|M.ulcerans_Agy99           AAEAANAS------------------------------------------
MMAR_4224|M.marinum_M               AAEAANVS------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
Mflv_1516|M.gilvum_PYR-GCK          TDSSSALA------------------------------------------
Mvan_5240|M.vanbaalenii_PYR-1       AAQSAVVQ------------------------------------------
MAB_0321c|M.abscessus_ATCC_199      AGAMANCN------------------------------------------
TH_4332|M.thermoresistible__bu      AFSASALG------------------------------------------
MAV_4827|M.avium_104                AALAQNVGGAMG--------------------------------------
MLBr_01556|M.leprae_Br4923          ATTAAPVQVDHS--------------------------------------
                                    .                                                 

Mb1121|M.bovis_AF2122/97            ----------AAQSTDQRLLDL------INGPTQALLGRPLIGDGANGGP
Rv1091|M.tuberculosis_H37Rv         ----------AAQSTDQRLLDL------INGPTQALLGRPLIGDGANGGP
MUL_4524|M.ulcerans_Agy99           ----------PLQTAAQELLAV------INTPTQTLLGRPLIGNGADGAL
MMAR_4224|M.marinum_M               ----------PLQAAAQDMLTA------IRAPAQALLGRPLIGNGADGAP
MSMEG_0868|M.smegmatis_MC2_155      TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
Mflv_1516|M.gilvum_PYR-GCK          ------------QASATPALRP------IIGP-----GGWLIGDGLDAAA
Mvan_5240|M.vanbaalenii_PYR-1       ------------QSSANPALRP------MIGD-----GGWLIGNGLDAAD
MAB_0321c|M.abscessus_ATCC_199      ----------------------------------------WIDDDCAT--
TH_4332|M.thermoresistible__bu      ------------MASFGPDWNPGGAFLGLIGP-----GGLLIGDGLNGTD
MAV_4827|M.avium_104                -------YERTAVLLVEPDTATLAVVETSDGSIPDVYKQQIRAESYGDAA
MLBr_01556|M.leprae_Br4923          ------AAVVPIVAGEGPSTAHREELAPPAGQPSEQPGVPLPGQQGTPAA
                                                                               :      

Mb1121|M.bovis_AF2122/97            GQ-----------DGGPGGLLYGNGGNGGTSTTAGVAGGNGGAAGLIGNG
Rv1091|M.tuberculosis_H37Rv         GQ-----------DGGPGGLLYGNGGNGGTSTTAGVAGGNGGAAGLIGNG
MUL_4524|M.ulcerans_Agy99           GQ-----------AGGDGGLLYGNGG------------------------
MMAR_4224|M.marinum_M               GQ-----------AGGDGGLLYGNGGNGGTSTTAGVAGGAGGSAGLIGNG
MSMEG_0868|M.smegmatis_MC2_155      DNP----------NGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFGNG
Mflv_1516|M.gilvum_PYR-GCK          DCTGE------ACNGGNGGLLGGNGGDG----------------------
Mvan_5240|M.vanbaalenii_PYR-1       DCQGD------ACNGGDGGILWGNGGNG----------------------
MAB_0321c|M.abscessus_ATCC_199      -------------RGGTG--------------------------------
TH_4332|M.thermoresistible__bu      AYIDENGVFHEATRGGNGGLLWGNGGKG----------------------
MAV_4827|M.avium_104                GQLSAMVAGLEKLESLPGGLLLVGSGVDVAPLKQVLQTTTFLDVSVAEEP
MLBr_01556|M.leprae_Br4923          PHPGHPG----MPTGPHPGPAPKPGGRPPRVGNNPFSSAQSVAR------
                                                  .                                   

Mb1121|M.bovis_AF2122/97            GAGGGGGAGAAGGNG-----GAGGWLYGNGGAGGAGGTSVIPGVAGGNGG
Rv1091|M.tuberculosis_H37Rv         GAGGGGGAGAAGGNG-----GAGGWLYGNGGAGGAGGTSVIPGVAGGNGG
MUL_4524|M.ulcerans_Agy99           ---------------------AGGWLFGQGGVGGNG--------------
MMAR_4224|M.marinum_M               GAGGGGGAGAVGGNG-----GAGGWLFGNGGAGGAGG-------------
MSMEG_0868|M.smegmatis_MC2_155      GNGGVGWAGLDGGNG-----GSGGLLMGIGGAGGAGGVG---------AD
Mflv_1516|M.gilvum_PYR-GCK          ---------RYGGAG-----GKAGLYFGDGGNGGDGVNAVYG-------A
Mvan_5240|M.vanbaalenii_PYR-1       ---------AHGGTG-----GDGGFWFGHGGNGGDG-DAVLD-------A
MAB_0321c|M.abscessus_ATCC_199      ---------------------------GTGGNGGPG--------------
TH_4332|M.thermoresistible__bu      ------------GNG-----LDAGLYTVPDPDNPGS--------------
MAV_4827|M.avium_104                ETALARGAALAAANAPLFASSTAALAYAQDPGTGAVDQYSLPDYLYVPVD
MLBr_01556|M.leprae_Br4923          --------PIPRPPAPRPSASPSSMSPRPGGAVGGGGPRPPRTGVPRPGG
                                                                 .                    

Mb1121|M.bovis_AF2122/97            AGGSAGLWGTGGAGGDGGNGRSGPVNVAGSAGGNGGAGGAAGLFGDAGAG
Rv1091|M.tuberculosis_H37Rv         AGGSAGLWGTGGAGGDGGNGRSGPVNVAGSAGGNGGAGGAAGLFGDAGAG
MUL_4524|M.ulcerans_Agy99           --------GTGGIGLDG---------VAGHIGG-----------GNAGNA
MMAR_4224|M.marinum_M               --ATPGIGGGGGAGGAGGIGGAAGLFGNGGAGGVGGDGGLN-YYGDGGVA
MSMEG_0868|M.smegmatis_MC2_155      GTSAHVDGGTGGTGGTGG-GTGGTGGIGGTGGGLFGLLGHSGSTGAAGAA
Mflv_1516|M.gilvum_PYR-GCK          NGALVSAAGQGGRGGDG------SLFGRGGDGGAGGNDDNTSNFTGTDAP
Mvan_5240|M.vanbaalenii_PYR-1       NGNVVRAATAGGAGGKGG-----YMFGNGGAGGKGGDAVYQNGVKKNGAL
MAB_0321c|M.abscessus_ATCC_199      --------GAGGPGGHGG----------------VIDFEVETFMDGVTLQ
TH_4332|M.thermoresistible__bu      TIQMYFEASDGADGGRGG-----FLFGNGGDGGNGGNVGGKNGADPVTAT
MAV_4827|M.avium_104                PEPGDDELAYSAVGEEDAESPTVVIEKLFLPEDSEPRRRPVLLVGSGLAV
MLBr_01556|M.leprae_Br4923          GRPGAPVGGRSDAGGGNYRGGGVGALPGGGSGGFRGRPGGGGHGGGGRPG
                                              .  *  .                                 

Mb1121|M.bovis_AF2122/97            GNGGKGGAGG--AAFSINF-------TAGDGGAGGAGGSGGHALLWGAGG
Rv1091|M.tuberculosis_H37Rv         GNGGKGGAGG--AAFSINF-------TAGDGGAGGAGGSGGHALLWGAGG
MUL_4524|M.ulcerans_Agy99           GNGGTGGSGG--LLF-------------GDGGDGGHGG---------AGF
MMAR_4224|M.marinum_M               GAGGDGGRGG--WLH-------------GDGGDGGAGGDGGRGLPGGDGG
MSMEG_0868|M.smegmatis_MC2_155      GNGGDGGNGG--FGYVLIAGPNVTVGSETRGGTGGAGGTGGQSTAAGPGK
Mflv_1516|M.gilvum_PYR-GCK          KNNATG----------------------GRGGNGGR-----SQLGQAGDG
Mvan_5240|M.vanbaalenii_PYR-1       AGGRGGDSGYLL----------------GNGGNGGAGGSDSNNLNVADDP
MAB_0321c|M.abscessus_ATCC_199      AKG-------------------------GRGGNGGHGG------------
TH_4332|M.thermoresistible__bu      VAADKSVAGG-------------------NGGNGGRGG------------
MAV_4827|M.avium_104                VGISAVLALEIALAIG-----------IRTTGTVALQPTPNQHLIVPTEQ
MLBr_01556|M.leprae_Br4923          QRGGAAGAFG------------------RPGGAPRRGRKSKRQKRQEYDS
                                                                   *                  

Mb1121|M.bovis_AF2122/97            AGGNGGSGG----------------TGGAGGS-----TAGAGGNGGAGGG
Rv1091|M.tuberculosis_H37Rv         AGGNGGSGG----------------TGGAGGS-----TAGAGGNGGAGGG
MUL_4524|M.ulcerans_Agy99           GGGNGSGNP----------------IGGQGG------NAGVAGNGGAGG-
MMAR_4224|M.marinum_M               SGGAGGGTG----------------LWGSGG---------AGGQGGTGGT
MSMEG_0868|M.smegmatis_MC2_155      GGGGGGGGGGAILIGANGGTVDGHAIGGNGGNGGNGSTTAAGGNGGTGGT
Mflv_1516|M.gilvum_PYR-GCK          GAGGQAWSE-------------------SGS--------ATGGAGGTG--
Mvan_5240|M.vanbaalenii_PYR-1       ATTNVNESA-------------------QNN--------AAGGAGGAGG-
MAB_0321c|M.abscessus_ATCC_199      ----------------------------------------AGGTGGTGG-
TH_4332|M.thermoresistible__bu      ------------------------------------LLFGLGGNGGNGGW
MAV_4827|M.avium_104                APAPPPVQASAPQ-----PKISVPEPVAAPKPLSPPVAAPLPAAPPPAAP
MLBr_01556|M.leprae_Br4923          MQAPVVGGVRLPHG-------NGETIRLARGASLSDFAEKIDANPAALVQ
                                                                              .       

Mb1121|M.bovis_AF2122/97            G----------------------GTGGLLFGNGG----------------
Rv1091|M.tuberculosis_H37Rv         G----------------------GTGGLLFGNGG----------------
MUL_4524|M.ulcerans_Agy99           ------------------------SAAMLFGNGG----------------
MMAR_4224|M.marinum_M               G----------------------LNGNAPFADGQH---------------
MSMEG_0868|M.smegmatis_MC2_155      GRVIAEGTGSTAEGTATGGDGGHSTGTGIGGNGGIGSVYAYGNNGAVSGT
Mflv_1516|M.gilvum_PYR-GCK          -------------------------GGTNYGKAG----------------
Mvan_5240|M.vanbaalenii_PYR-1       ------------------------VGGILNGNGG----------------
MAB_0321c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4332|M.thermoresistible__bu      S-----------------------TTSYLDARGG----------------
MAV_4827|M.avium_104                P----------------------LPEAPPIPAAPPVVPVPVVVPPVPVPV
MLBr_01556|M.leprae_Br4923          ALFN--------------------LGEMVTATQSVGDETLELLGSEMNYN
                                                                                      

Mb1121|M.bovis_AF2122/97            ----AGGHGAAAGNGLAAGNGVSSSGGGGAGGTGGAGGDGGAGG------
Rv1091|M.tuberculosis_H37Rv         ----AGGHGAAAGNGLAAGNGVSSSGGGGAGGTGGAGGDGGAGG------
MUL_4524|M.ulcerans_Agy99           ----AGGN------------------------------------------
MMAR_4224|M.marinum_M               PVILDGGHGGTGGNGGAAGNG-----------------------------
MSMEG_0868|M.smegmatis_MC2_155      ATGGRGGDGIDGGTGGAGGMGEIYSGADGEATGISAGGDGGSATGADSLG
Mflv_1516|M.gilvum_PYR-GCK          ----SGGDGGSG--------------------------------------
Mvan_5240|M.vanbaalenii_PYR-1       ----HGGDGGS---------------------------------------
MAB_0321c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4332|M.thermoresistible__bu      --------------------------------------------------
MAV_4827|M.avium_104                PVRIPVPDPVSPPQLLAPPRLSVPQPVQPPVR------------------
MLBr_01556|M.leprae_Br4923          VQVVSPEDEDRELLEPFDLTYGEDQGDEDELQVRPPVVTVMGHVDHG---
                                                                                      

Mb1121|M.bovis_AF2122/97            ---------------AGGNARLWGVGGAGGAGGDGGAGGAGG--------
Rv1091|M.tuberculosis_H37Rv         ---------------AGGNARLWGVGGAGGAGGDGGAGGAGG--------
MUL_4524|M.ulcerans_Agy99           ----------------------------GGSGGDGGHG------------
MMAR_4224|M.marinum_M               -------------------------GLLFGNGGNGGLGGMGG--------
MSMEG_0868|M.smegmatis_MC2_155      GRGGTSWVQAGYGPTTGGKASGTAKAGHGGKASDGGKGGNGGDALVMAAG
Mflv_1516|M.gilvum_PYR-GCK          ------------------------SAWADGKVGKGGVGGNGG--------
Mvan_5240|M.vanbaalenii_PYR-1       ------------------------ADSANGNAT-GGSGGRGG--------
MAB_0321c|M.abscessus_ATCC_199      ---------------------------------KGGDG------------
TH_4332|M.thermoresistible__bu      ---------------------------NGGNGGLGGVLRPGG--------
MAV_4827|M.avium_104                ------------------------VPQPPSPPQVGGTVPQSP--------
MLBr_01556|M.leprae_Br4923          ----------------KTRLLDTIRKANVREAEAGGITQHIGAYQVGVDL
                                                                      **              

Mb1121|M.bovis_AF2122/97            ----------KGGSGLSGNANGGAGGDS----------------------
Rv1091|M.tuberculosis_H37Rv         ----------KGGSGLSGNANGGAGGDS----------------------
MUL_4524|M.ulcerans_Agy99           -----------GNSALS--VPGSIGGDA----------------------
MMAR_4224|M.marinum_M               ----------GGGNGLP---STGVGGDG----------------------
MSMEG_0868|M.smegmatis_MC2_155      ATGVATGNTAIGGNGGAASANGAVGGNGGFTNIAAIHGSITDSSATSGHG
Mflv_1516|M.gilvum_PYR-GCK          ---------------GSRADSG-SGGAG----------------------
Mvan_5240|M.vanbaalenii_PYR-1       ---------------LAHSNAGGTGGNG----------------------
MAB_0321c|M.abscessus_ATCC_199      -------------------DDCEFGRTG----------------------
TH_4332|M.thermoresistible__bu      --------------LLSLLLPSGAASEP----------------------
MAV_4827|M.avium_104                ---------------PQHQTPPGEGTPP----------------------
MLBr_01556|M.leprae_Br4923          DGSERLITFIDTPGHEAFTAMRARGAKAT---------------------
                                                            .                         

Mb1121|M.bovis_AF2122/97            -----GRGGTGG---------------------AGGEGGAAGLLVGTGGH
Rv1091|M.tuberculosis_H37Rv         -----GRGGTGG---------------------AGGEGGAAGLLVGTGGH
MUL_4524|M.ulcerans_Agy99           -----GAGGTGG---------------------SAGK---SGLLFGAG--
MMAR_4224|M.marinum_M               -----GDGGNGG---------------------TAGN---GGWLIGNG--
MSMEG_0868|M.smegmatis_MC2_155      GAAQGGNGGNGGNGWVQAYDPNGPAGTTIDKGKAAGGNGGDGGFNGTGGA
Mflv_1516|M.gilvum_PYR-GCK          --------GTGG----------------------------DGWGYEEAD-
Mvan_5240|M.vanbaalenii_PYR-1       --------GNGG----------------------------DAEADDAGKT
MAB_0321c|M.abscessus_ATCC_199      --------GNGG--------------------------------------
TH_4332|M.thermoresistible__bu      ----------GG--------------------------------------
MAV_4827|M.avium_104                --KPDGPGNYGG-----------------------------GHVPTPG--
MLBr_01556|M.leprae_Br4923          DIAILVVAADDG------------------VMPQTVEAINHAQAADVPIV
                                              .*                                      

Mb1121|M.bovis_AF2122/97            GGDGGAGGAAVKGGDGGAAAGTGIAGAGGRGGAGGSGG----SGGDGGGG
Rv1091|M.tuberculosis_H37Rv         GGDGGAGGAAVKGGDGGAAAGTGIAGAGGRGGAGGSGG----SGGDGGGG
MUL_4524|M.ulcerans_Agy99           -------------------------GAGGQGGGGGTGG----DGGD----
MMAR_4224|M.marinum_M               -------------------------GTGGQGGAGFAGG----TGADNVSA
MSMEG_0868|M.smegmatis_MC2_155      TGGRGGDGAGASVWKANGQHSTGQTDTGGNGGRGGDGGTFVNAGANGNGG
Mflv_1516|M.gilvum_PYR-GCK          -------------------------AQGGNGGAGGLT-------------
Mvan_5240|M.vanbaalenii_PYR-1       -------------------------AKGGNGGAGGTSG------------
MAB_0321c|M.abscessus_ATCC_199      --------------------------TGGRGGDGNFAG------------
TH_4332|M.thermoresistible__bu      ------------------------LFTGGNGGNGGLAIAN----------
MAV_4827|M.avium_104                --------------------------AGGSGGSGGGHVP-----------
MLBr_01556|M.leprae_Br4923          VAVNKIDKEGADPAKIRGQLTEYGLVAEDFGGDTMFIDISAKVGTNIEAL
                                                                . **                  

Mb1121|M.bovis_AF2122/97            AAGPAGWLFGDGGAGGNGGAAAAGGAGGQAGG------------------
Rv1091|M.tuberculosis_H37Rv         AAGPAGWLFGDGGAGGNGGAAAAGGAGGQAGG------------------
MUL_4524|M.ulcerans_Agy99           ------------CAGAN---------------------------------
MMAR_4224|M.marinum_M               GR--------PGGAGGTGGIGAGGGNAGLIG-------------------
MSMEG_0868|M.smegmatis_MC2_155      AGGAGGVSEGEGGTGGHGGDGGRGGDGALGGNGGTGGVGLGNGGKGGNGG
Mflv_1516|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5240|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0321c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4332|M.thermoresistible__bu      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          LEAVLLTADAALDLRANSGMEAQGVAIEAHLDRGRGPVATVLVQRG----
                                                                                      

Mb1121|M.bovis_AF2122/97            ---------------GGGNGGNGGN---------------GGNGGNGGNG
Rv1091|M.tuberculosis_H37Rv         ---------------GGGNGGNGGN---------------GGNGGNGGNG
MUL_4524|M.ulcerans_Agy99           ------------------IGGDGGA---------------GGAGGLGGNG
MMAR_4224|M.marinum_M               ---------------TGGSGGNGGM---------------GGHGGDSGYG
MSMEG_0868|M.smegmatis_MC2_155      NGGNGGTYVDPSHTGAGGNGGNGGAGRIRVNNGTATGTATGGNGGNGGNG
Mflv_1516|M.gilvum_PYR-GCK          -------------------GGRGGH----------------GGAAESLNG
Mvan_5240|M.vanbaalenii_PYR-1       ----------------TGQGGSGGN----------------GGNAVGDDA
MAB_0321c|M.abscessus_ATCC_199      ------------------TGGNGGA-----------------ILVKCQHD
TH_4332|M.thermoresistible__bu      ----------------HWVGITDGVP---------------GPDDDAVSS
MAV_4827|M.avium_104                ---------------TPGAGGSGGS---------------GGGHVPTPGT
MLBr_01556|M.leprae_Br4923          -------------TLRIGDSVVAGDAYGRVRRMVDEHGVDIEAALPSSPV
                                                       .   *                          

Mb1121|M.bovis_AF2122/97            ATGGWLYGNGGAGGQGATAGAGGAGANGVSSTNGG---------------
Rv1091|M.tuberculosis_H37Rv         ATGGWLYGNGGAGGQGATAGAGGAGANGVSSTNGGG--------------
MUL_4524|M.ulcerans_Agy99           TDGGWLYGNGG---------------------------------------
MMAR_4224|M.marinum_M               DQTGGQGGNGGMGGAG----------------------------------
MSMEG_0868|M.smegmatis_MC2_155      DADGHRGGKGGDGGEALIRATVIGSNASGTATGGDGGNGGTLGATNGTGG
Mflv_1516|M.gilvum_PYR-GCK          DATGGNGGNGG---------------------------------------
Mvan_5240|M.vanbaalenii_PYR-1       HAVGGSGGAGG---------------------------------------
MAB_0321c|M.abscessus_ATCC_199      LSLGTHPMDVS---------------------------------------
TH_4332|M.thermoresistible__bu      SAYGGHGGHGAG--------------------------------------
MAV_4827|M.avium_104                GGPGGTGGSGGG--------------------------------------
MLBr_01556|M.leprae_Br4923          QVIGFTSVPGAGDNFLVVDEDRIARQIADRRSARKR--------------
                                       *      .                                       

Mb1121|M.bovis_AF2122/97            ------------------GNGGIGGTGGSGGAGGNAGLLGVGGAGGHGAS
Rv1091|M.tuberculosis_H37Rv         ----------------TGGNGGIGGTGGSGGAGGNAGLLGVGGAGGHGAS
MUL_4524|M.ulcerans_Agy99           --------------------------------------------------
MMAR_4224|M.marinum_M               --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      AATIVAYNVVQANPQASGTATDGHGGSGINGGHGGNGGQGTIEANGPSAV
Mflv_1516|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5240|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0321c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4332|M.thermoresistible__bu      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          ----------------------------------NALAARSRKRISLEDL
                                                                                      

Mb1121|M.bovis_AF2122/97            GGAGDRGGAGGTGFISSDGGAGGD--------------------GGDGG-
Rv1091|M.tuberculosis_H37Rv         GGAGDRGGAGGTGFISSDGGAGGD--------------------GGDGG-
MUL_4524|M.ulcerans_Agy99           ------------------GGAGGQ--------------------GGDGG-
MMAR_4224|M.marinum_M               ------GAAGNGGLLLGSGSRGGD--------------------GGDGG-
MSMEG_0868|M.smegmatis_MC2_155      ASGIGAGGNGGDGIDGGLGGNGGDGVVNTTANAANPGSATGTATGGDGGK
Mflv_1516|M.gilvum_PYR-GCK          ------------GARV--VGDGGD--------------------GGDGG-
Mvan_5240|M.vanbaalenii_PYR-1       ------------GVRLGTGGDGGD--------------------GGDAV-
MAB_0321c|M.abscessus_ATCC_199      ------------------AGTGGN--------------------GGIGG-
TH_4332|M.thermoresistible__bu      ------------------PGSGGN--------------------------
MAV_4827|M.avium_104                --------------HVPTPGAGTP--------------------GGSGG-
MLBr_01556|M.leprae_Br4923          DSALKETSQLNLILKGDNAGTVEALEEALMGIQVDDEVALRVIDRGVGGI
                                                       .                              

Mb1121|M.bovis_AF2122/97            ------NGGAGGTGGLLFGAGGNGGPGGSGGAADIGGNGGAGNGGGTDGN
Rv1091|M.tuberculosis_H37Rv         ------NGGAGGTGGLLFGAGGNGGPGGSGGAADIGGNGGAGNGGGTDGN
MUL_4524|M.ulcerans_Agy99           ------HGGS----------------------------------------
MMAR_4224|M.marinum_M               ------NGGEGR--------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      ATGTASQGGNGGPSWVQSGYGSTLGGNATGTATAGKGGEASNGGVAGNGG
Mflv_1516|M.gilvum_PYR-GCK          -----YGWGG----------------------------------------
Mvan_5240|M.vanbaalenii_PYR-1       -----SEDGN----------------------------------------
MAB_0321c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4332|M.thermoresistible__bu      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
MLBr_01556|M.leprae_Br4923          TETNVNLASASDAIIIGFNVRAEG--------------------------
                                                                                      

Mb1121|M.bovis_AF2122/97            GGNGGSGGGAGSGGDGGGAGGNGAWLFGNGGAGGGGGKGGNGAGGGLGGG
Rv1091|M.tuberculosis_H37Rv         GGNGGSGGGAGSGGDGGGAGGNGAWLFGNGGAGGGGGKGGNGAGGGLGGG
MUL_4524|M.ulcerans_Agy99           --------------------------------------------------
MMAR_4224|M.marinum_M               -------------------------------------------------G
MSMEG_0868|M.smegmatis_MC2_155      NALVMAAGTTGVATGNTATGGDGGAATTAGATGGAGGFSNIAAIHGAITD
Mflv_1516|M.gilvum_PYR-GCK          -------------------------------------------------V
Mvan_5240|M.vanbaalenii_PYR-1       -------------------------------------------------A
MAB_0321c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4332|M.thermoresistible__bu      --------------------------------------------------
MAV_4827|M.avium_104                -------------------------------------------------G
MLBr_01556|M.leprae_Br4923          -------------------------------------------------K
                                                                                      

Mb1121|M.bovis_AF2122/97            SFGLPGLNGSG---------------------------------GDGGDG
Rv1091|M.tuberculosis_H37Rv         SFGLPGLNGSG---------------------------------GDGGDG
MUL_4524|M.ulcerans_Agy99           PVGFDGKSGVG---------------------------------GDGGDG
MMAR_4224|M.marinum_M               GFSVP-QHGVG---------------------------------GQGGTG
MSMEG_0868|M.smegmatis_MC2_155      STAISGHGGAGNGGNGGKGADGWVQAYDPAGPVGSKIANSSAVAGNGGDG
Mflv_1516|M.gilvum_PYR-GCK          PDEEGDPVGTGN--------------------------------GKGGNG
Mvan_5240|M.vanbaalenii_PYR-1       TGGKGGDGGSVD--------------------------------LTGGGG
MAB_0321c|M.abscessus_ATCC_199      --------------------------------------------GGGGGG
TH_4332|M.thermoresistible__bu      ----------------------------------------------GGSA
MAV_4827|M.avium_104                HLPFPGAGS-----------------------------------TPGGSG
MLBr_01556|M.leprae_Br4923          ATELASREGVEIR--------------------------YYLVIYQAIDD
                                                                                  .   

Mb1121|M.bovis_AF2122/97            GNGAPGGVLYGNGGAGGQGSSGGIGGPGAT--GGAGGKGGDGGDAQLIGD
Rv1091|M.tuberculosis_H37Rv         GNGAPGGVLYGNGGAGGQGSSGGIGGPGAT--GGAGGKGGDGGDAQLIGD
MUL_4524|M.ulcerans_Agy99           GN------------------------------------------ARIIGN
MMAR_4224|M.marinum_M               GNGSDGGWLYGDGGAGGAGGNGGFGGSGVQ--NGAGGDAGSGGDSRLIGD
MSMEG_0868|M.smegmatis_MC2_155      GVNGTGGASGGDGGNGGNTSVWKSGGQTADGEHNTGGNGGNGGDGSEPGP
Mflv_1516|M.gilvum_PYR-GCK          GAGGNGGVAVGN-----------------------GGNGGIGGDGYNETG
Mvan_5240|M.vanbaalenii_PYR-1       GAGGEGGDADGDEKA-------------------TGGSGGSGGTGGLGGD
MAB_0321c|M.abscessus_ATCC_199      SVGANG-----------------------------ATTGVFSSSSDCSGP
TH_4332|M.thermoresistible__bu      VANSLGN--------------------------AIAGNGGDAGRFVLIGP
MAV_4827|M.avium_104                GGHLPTP-----------------------------GAGTPGGGLGGFGG
MLBr_01556|M.leprae_Br4923          IEKALRGMLKPIYEENQLGRAEIRALFRSSKVGIIAGCIISSGVVRRNAK
                                                                                      

Mb1121|M.bovis_AF2122/97            GG---NGGNGGAGGTG-GTPGPGGPGGSGGLGG--LLFGQTGTAGVSP--
Rv1091|M.tuberculosis_H37Rv         GG---NGGNGGAGGTG-GTPGPGGPGGSGGLGG--LLFGQTGTAGVSP--
MUL_4524|M.ulcerans_Agy99           GG---NGGNGGNGGVG-STDGD---GGQGGAAG--LLFGQPGSMGT----
MMAR_4224|M.marinum_M               GG---AAG---AGGTG-APPGA---DGHSGADG--LLSAALGA-------
MSMEG_0868|M.smegmatis_MC2_155      GGNG-AGGAGGNGGTGGTTAGGSGNGGNGGNGGNGGADGTPGTAGTTGAN
Mflv_1516|M.gilvum_PYR-GCK          GTKTPVAGKGGPGGAGGAIGSDGDAGADGETETSSGSSGSAGSADSDD--
Mvan_5240|M.vanbaalenii_PYR-1       GGAGGDGGDAVADDEGGATAGSGGDGGFGGTDGDDGSASDGADAPATD--
MAB_0321c|M.abscessus_ATCC_199      GP---QPNPGSPGDPGTSVAVS---GAQGNPGQAQFLIVP----------
TH_4332|M.thermoresistible__bu      GG---NGGNGGTGLXXXPRPRRRRNHRRTRRRPNGRRPRPPPGR------
MAV_4827|M.avium_104                GHAP-APGGGLGGGGGHAPAPGGGLGGFGGGHSGGGLGGLGGGHK-----
MLBr_01556|M.leprae_Br4923          VRLLRDNIVVTDNLTVTSLRREKDDVTEVREGFECGMTLGYSDIKEGDVI
                                                .                                     

Mb1121|M.bovis_AF2122/97            -----------
Rv1091|M.tuberculosis_H37Rv         -----------
MUL_4524|M.ulcerans_Agy99           -----------
MMAR_4224|M.marinum_M               -----------
MSMEG_0868|M.smegmatis_MC2_155      NP---------
Mflv_1516|M.gilvum_PYR-GCK          -----------
Mvan_5240|M.vanbaalenii_PYR-1       -----------
MAB_0321c|M.abscessus_ATCC_199      -----------
TH_4332|M.thermoresistible__bu      -----------
MAV_4827|M.avium_104                -----------
MLBr_01556|M.leprae_Br4923          ESYELVEKQRA