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aa seq not available
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. thermoresistible (build 8) | TH_4332 | - | - | 100% (402) | - |
M. thermoresistible (build 8) | TH_3810 | - | 4e-27 | 36.49% (285) | PUTATIVE - |
M. thermoresistible (build 8) | TH_2853 | - | 3e-07 | 31.47% (143) | PUTATIVE - |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1121 | PE_PGRS22 | 2e-42 | 36.72% (403) | PE-PGRS family protein |
M. gilvum PYR-GCK | Mflv_1516 | - | 2e-45 | 38.70% (385) | hypothetical protein Mflv_1516 |
M. tuberculosis H37Rv | Rv1091 | PE_PGRS22 | 5e-43 | 35.99% (414) | PE-PGRS family protein |
M. leprae Br4923 | MLBr_01556 | infB | 5e-05 | 29.49% (156) | translation initiation factor IF-2 |
M. abscessus ATCC 19977 | MAB_0321c | - | 6e-19 | 34.59% (292) | hypothetical protein MAB_0321c |
M. marinum M | MMAR_4224 | - | 4e-44 | 37.84% (407) | PE-PGRS family protein |
M. avium 104 | MAV_4827 | - | 2e-12 | 34.15% (164) | hypothetical protein MAV_4827 |
M. smegmatis MC2 155 | MSMEG_0868 | - | 6e-37 | 37.33% (300) | hypothetical protein MSMEG_0868 |
M. ulcerans Agy99 | MUL_4524 | - | 2e-40 | 34.24% (403) | PE-PGRS family protein |
M. vanbaalenii PYR-1 | Mvan_5240 | - | 3e-44 | 35.61% (424) | PE-PGRS family protein |
CLUSTAL 2.0.9 multiple sequence alignment Mb1121|M.bovis_AF2122/97 ------------MSFVIAAPEALVAVASDLAGIGSALAEAN-AAALAPTT Rv1091|M.tuberculosis_H37Rv ------------MSFVIAAPEALVAVASDLAGIGSALAEAN-AAALAPTT MUL_4524|M.ulcerans_Agy99 ------------MSYLVAVPEMLASAALDLDNIGSTITAAN-AAAAAPTT MMAR_4224|M.marinum_M ------------MSFLVTAPEILAAAATDLDGIGAAIGAAN-AAAAAPTT MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES Mflv_1516|M.gilvum_PYR-GCK -----------------------MARHANTSDRSAAIRRYLGAGITAGMA Mvan_5240|M.vanbaalenii_PYR-1 -----------------------MARHAKKSDRSMAIRTYLTAGLTAGVT MAB_0321c|M.abscessus_ATCC_199 --------------------------MANIISNG---------------- TH_4332|M.thermoresistible__bu -------------------------MPFITSGAAFVGGAAMLLAGPGGVS MAV_4827|M.avium_104 -MNIVLGVSMAPSSIQMVVLEGEYADGATVEEDAIDVTGADDAATASAPD MLBr_01556|M.leprae_Br4923 -----MAGKARVHELAKELGVTSKEVLARLNEQGEFVKSASSTVEAPVAR Mb1121|M.bovis_AF2122/97 ALLAAG--------------------------ADEVSAAIAALFGAHGQA Rv1091|M.tuberculosis_H37Rv ALLAAG--------------------------ADEVSAAIAALFGAHGQA MUL_4524|M.ulcerans_Agy99 AVLAAG--------------------------ADEISAAVAALFTGHAQA MMAR_4224|M.marinum_M AVLAAG--------------------------ADEISAAMASLFTAHAQA MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT Mflv_1516|M.gilvum_PYR-GCK SAALAG-------------------------------VGTALLTDVDAST Mvan_5240|M.vanbaalenii_PYR-1 GAALAG-------------------------------VGTLLLADGDVSG MAB_0321c|M.abscessus_ATCC_199 -------------------------------------------PDGDAGA TH_4332|M.thermoresistible__bu ALEAAG-------------------------------SAPRTVEYEYSLV MAV_4827|M.avium_104 RVISAILG-------------------------TREGAADAGLQLSSIGV MLBr_01556|M.leprae_Br4923 RLRESFG-----------------------------GIKPAADKGAEQVA Mb1121|M.bovis_AF2122/97 YQTVSAQASAFHAQFVQALTGGGG-----------------------AYA Rv1091|M.tuberculosis_H37Rv YQTVSAQASAFHAQFVQALTGGGG-----------------------AYA MUL_4524|M.ulcerans_Agy99 YQWLGAQAGAFHSQFIQALTGSGS-----------------------AYA MMAR_4224|M.marinum_M YQGLSVQVGAFHNQFVQALTGAGG-----------------------AYA MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA Mflv_1516|M.gilvum_PYR-GCK STDPRVQLVSNEEELLWLTLDAGSD----------------------RAK Mvan_5240|M.vanbaalenii_PYR-1 PAQIEVQLVSNEEDILWLSLNGGSD----------------------RRS MAB_0321c|M.abscessus_ATCC_199 TGAQGSQGATG--------------------------------------A TH_4332|M.thermoresistible__bu ACDSTLPLMCEAGDSVGGLGGASHD-----------------------RS MAV_4827|M.avium_104 TWTDQLEAAALRDALAARRIDNVMLVS------------------AFLAA MLBr_01556|M.leprae_Br4923 TKAQAKRLGESLDQTLDRALDKAVAG----------------------NG Mb1121|M.bovis_AF2122/97 AAEAANVS------------------------------------------ Rv1091|M.tuberculosis_H37Rv AAEAANVS------------------------------------------ MUL_4524|M.ulcerans_Agy99 AAEAANAS------------------------------------------ MMAR_4224|M.marinum_M AAEAANVS------------------------------------------ MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP Mflv_1516|M.gilvum_PYR-GCK TDSSSALA------------------------------------------ Mvan_5240|M.vanbaalenii_PYR-1 AAQSAVVQ------------------------------------------ MAB_0321c|M.abscessus_ATCC_199 AGAMANCN------------------------------------------ TH_4332|M.thermoresistible__bu AFSASALG------------------------------------------ MAV_4827|M.avium_104 AALAQNVGGAMG-------------------------------------- MLBr_01556|M.leprae_Br4923 ATTAAPVQVDHS-------------------------------------- . Mb1121|M.bovis_AF2122/97 ----------AAQSTDQRLLDL------INGPTQALLGRPLIGDGANGGP Rv1091|M.tuberculosis_H37Rv ----------AAQSTDQRLLDL------INGPTQALLGRPLIGDGANGGP MUL_4524|M.ulcerans_Agy99 ----------PLQTAAQELLAV------INTPTQTLLGRPLIGNGADGAL MMAR_4224|M.marinum_M ----------PLQAAAQDMLTA------IRAPAQALLGRPLIGNGADGAP MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA Mflv_1516|M.gilvum_PYR-GCK ------------QASATPALRP------IIGP-----GGWLIGDGLDAAA Mvan_5240|M.vanbaalenii_PYR-1 ------------QSSANPALRP------MIGD-----GGWLIGNGLDAAD MAB_0321c|M.abscessus_ATCC_199 ----------------------------------------WIDDDCAT-- TH_4332|M.thermoresistible__bu ------------MASFGPDWNPGGAFLGLIGP-----GGLLIGDGLNGTD MAV_4827|M.avium_104 -------YERTAVLLVEPDTATLAVVETSDGSIPDVYKQQIRAESYGDAA MLBr_01556|M.leprae_Br4923 ------AAVVPIVAGEGPSTAHREELAPPAGQPSEQPGVPLPGQQGTPAA : Mb1121|M.bovis_AF2122/97 GQ-----------DGGPGGLLYGNGGNGGTSTTAGVAGGNGGAAGLIGNG Rv1091|M.tuberculosis_H37Rv GQ-----------DGGPGGLLYGNGGNGGTSTTAGVAGGNGGAAGLIGNG MUL_4524|M.ulcerans_Agy99 GQ-----------AGGDGGLLYGNGG------------------------ MMAR_4224|M.marinum_M GQ-----------AGGDGGLLYGNGGNGGTSTTAGVAGGAGGSAGLIGNG MSMEG_0868|M.smegmatis_MC2_155 DNP----------NGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFGNG Mflv_1516|M.gilvum_PYR-GCK DCTGE------ACNGGNGGLLGGNGGDG---------------------- Mvan_5240|M.vanbaalenii_PYR-1 DCQGD------ACNGGDGGILWGNGGNG---------------------- MAB_0321c|M.abscessus_ATCC_199 -------------RGGTG-------------------------------- TH_4332|M.thermoresistible__bu AYIDENGVFHEATRGGNGGLLWGNGGKG---------------------- MAV_4827|M.avium_104 GQLSAMVAGLEKLESLPGGLLLVGSGVDVAPLKQVLQTTTFLDVSVAEEP MLBr_01556|M.leprae_Br4923 PHPGHPG----MPTGPHPGPAPKPGGRPPRVGNNPFSSAQSVAR------ . Mb1121|M.bovis_AF2122/97 GAGGGGGAGAAGGNG-----GAGGWLYGNGGAGGAGGTSVIPGVAGGNGG Rv1091|M.tuberculosis_H37Rv GAGGGGGAGAAGGNG-----GAGGWLYGNGGAGGAGGTSVIPGVAGGNGG MUL_4524|M.ulcerans_Agy99 ---------------------AGGWLFGQGGVGGNG-------------- MMAR_4224|M.marinum_M GAGGGGGAGAVGGNG-----GAGGWLFGNGGAGGAGG------------- MSMEG_0868|M.smegmatis_MC2_155 GNGGVGWAGLDGGNG-----GSGGLLMGIGGAGGAGGVG---------AD Mflv_1516|M.gilvum_PYR-GCK ---------RYGGAG-----GKAGLYFGDGGNGGDGVNAVYG-------A Mvan_5240|M.vanbaalenii_PYR-1 ---------AHGGTG-----GDGGFWFGHGGNGGDG-DAVLD-------A MAB_0321c|M.abscessus_ATCC_199 ---------------------------GTGGNGGPG-------------- TH_4332|M.thermoresistible__bu ------------GNG-----LDAGLYTVPDPDNPGS-------------- MAV_4827|M.avium_104 ETALARGAALAAANAPLFASSTAALAYAQDPGTGAVDQYSLPDYLYVPVD MLBr_01556|M.leprae_Br4923 --------PIPRPPAPRPSASPSSMSPRPGGAVGGGGPRPPRTGVPRPGG . Mb1121|M.bovis_AF2122/97 AGGSAGLWGTGGAGGDGGNGRSGPVNVAGSAGGNGGAGGAAGLFGDAGAG Rv1091|M.tuberculosis_H37Rv AGGSAGLWGTGGAGGDGGNGRSGPVNVAGSAGGNGGAGGAAGLFGDAGAG MUL_4524|M.ulcerans_Agy99 --------GTGGIGLDG---------VAGHIGG-----------GNAGNA MMAR_4224|M.marinum_M --ATPGIGGGGGAGGAGGIGGAAGLFGNGGAGGVGGDGGLN-YYGDGGVA MSMEG_0868|M.smegmatis_MC2_155 GTSAHVDGGTGGTGGTGG-GTGGTGGIGGTGGGLFGLLGHSGSTGAAGAA Mflv_1516|M.gilvum_PYR-GCK NGALVSAAGQGGRGGDG------SLFGRGGDGGAGGNDDNTSNFTGTDAP Mvan_5240|M.vanbaalenii_PYR-1 NGNVVRAATAGGAGGKGG-----YMFGNGGAGGKGGDAVYQNGVKKNGAL MAB_0321c|M.abscessus_ATCC_199 --------GAGGPGGHGG----------------VIDFEVETFMDGVTLQ TH_4332|M.thermoresistible__bu TIQMYFEASDGADGGRGG-----FLFGNGGDGGNGGNVGGKNGADPVTAT MAV_4827|M.avium_104 PEPGDDELAYSAVGEEDAESPTVVIEKLFLPEDSEPRRRPVLLVGSGLAV MLBr_01556|M.leprae_Br4923 GRPGAPVGGRSDAGGGNYRGGGVGALPGGGSGGFRGRPGGGGHGGGGRPG . * . Mb1121|M.bovis_AF2122/97 GNGGKGGAGG--AAFSINF-------TAGDGGAGGAGGSGGHALLWGAGG Rv1091|M.tuberculosis_H37Rv GNGGKGGAGG--AAFSINF-------TAGDGGAGGAGGSGGHALLWGAGG MUL_4524|M.ulcerans_Agy99 GNGGTGGSGG--LLF-------------GDGGDGGHGG---------AGF MMAR_4224|M.marinum_M GAGGDGGRGG--WLH-------------GDGGDGGAGGDGGRGLPGGDGG MSMEG_0868|M.smegmatis_MC2_155 GNGGDGGNGG--FGYVLIAGPNVTVGSETRGGTGGAGGTGGQSTAAGPGK Mflv_1516|M.gilvum_PYR-GCK KNNATG----------------------GRGGNGGR-----SQLGQAGDG Mvan_5240|M.vanbaalenii_PYR-1 AGGRGGDSGYLL----------------GNGGNGGAGGSDSNNLNVADDP MAB_0321c|M.abscessus_ATCC_199 AKG-------------------------GRGGNGGHGG------------ TH_4332|M.thermoresistible__bu VAADKSVAGG-------------------NGGNGGRGG------------ MAV_4827|M.avium_104 VGISAVLALEIALAIG-----------IRTTGTVALQPTPNQHLIVPTEQ MLBr_01556|M.leprae_Br4923 QRGGAAGAFG------------------RPGGAPRRGRKSKRQKRQEYDS * Mb1121|M.bovis_AF2122/97 AGGNGGSGG----------------TGGAGGS-----TAGAGGNGGAGGG Rv1091|M.tuberculosis_H37Rv AGGNGGSGG----------------TGGAGGS-----TAGAGGNGGAGGG MUL_4524|M.ulcerans_Agy99 GGGNGSGNP----------------IGGQGG------NAGVAGNGGAGG- MMAR_4224|M.marinum_M SGGAGGGTG----------------LWGSGG---------AGGQGGTGGT MSMEG_0868|M.smegmatis_MC2_155 GGGGGGGGGGAILIGANGGTVDGHAIGGNGGNGGNGSTTAAGGNGGTGGT Mflv_1516|M.gilvum_PYR-GCK GAGGQAWSE-------------------SGS--------ATGGAGGTG-- Mvan_5240|M.vanbaalenii_PYR-1 ATTNVNESA-------------------QNN--------AAGGAGGAGG- MAB_0321c|M.abscessus_ATCC_199 ----------------------------------------AGGTGGTGG- TH_4332|M.thermoresistible__bu ------------------------------------LLFGLGGNGGNGGW MAV_4827|M.avium_104 APAPPPVQASAPQ-----PKISVPEPVAAPKPLSPPVAAPLPAAPPPAAP MLBr_01556|M.leprae_Br4923 MQAPVVGGVRLPHG-------NGETIRLARGASLSDFAEKIDANPAALVQ . Mb1121|M.bovis_AF2122/97 G----------------------GTGGLLFGNGG---------------- Rv1091|M.tuberculosis_H37Rv G----------------------GTGGLLFGNGG---------------- MUL_4524|M.ulcerans_Agy99 ------------------------SAAMLFGNGG---------------- MMAR_4224|M.marinum_M G----------------------LNGNAPFADGQH--------------- MSMEG_0868|M.smegmatis_MC2_155 GRVIAEGTGSTAEGTATGGDGGHSTGTGIGGNGGIGSVYAYGNNGAVSGT Mflv_1516|M.gilvum_PYR-GCK -------------------------GGTNYGKAG---------------- Mvan_5240|M.vanbaalenii_PYR-1 ------------------------VGGILNGNGG---------------- MAB_0321c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4332|M.thermoresistible__bu S-----------------------TTSYLDARGG---------------- MAV_4827|M.avium_104 P----------------------LPEAPPIPAAPPVVPVPVVVPPVPVPV MLBr_01556|M.leprae_Br4923 ALFN--------------------LGEMVTATQSVGDETLELLGSEMNYN Mb1121|M.bovis_AF2122/97 ----AGGHGAAAGNGLAAGNGVSSSGGGGAGGTGGAGGDGGAGG------ Rv1091|M.tuberculosis_H37Rv ----AGGHGAAAGNGLAAGNGVSSSGGGGAGGTGGAGGDGGAGG------ MUL_4524|M.ulcerans_Agy99 ----AGGN------------------------------------------ MMAR_4224|M.marinum_M PVILDGGHGGTGGNGGAAGNG----------------------------- MSMEG_0868|M.smegmatis_MC2_155 ATGGRGGDGIDGGTGGAGGMGEIYSGADGEATGISAGGDGGSATGADSLG Mflv_1516|M.gilvum_PYR-GCK ----SGGDGGSG-------------------------------------- Mvan_5240|M.vanbaalenii_PYR-1 ----HGGDGGS--------------------------------------- MAB_0321c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4332|M.thermoresistible__bu -------------------------------------------------- MAV_4827|M.avium_104 PVRIPVPDPVSPPQLLAPPRLSVPQPVQPPVR------------------ MLBr_01556|M.leprae_Br4923 VQVVSPEDEDRELLEPFDLTYGEDQGDEDELQVRPPVVTVMGHVDHG--- Mb1121|M.bovis_AF2122/97 ---------------AGGNARLWGVGGAGGAGGDGGAGGAGG-------- Rv1091|M.tuberculosis_H37Rv ---------------AGGNARLWGVGGAGGAGGDGGAGGAGG-------- MUL_4524|M.ulcerans_Agy99 ----------------------------GGSGGDGGHG------------ MMAR_4224|M.marinum_M -------------------------GLLFGNGGNGGLGGMGG-------- MSMEG_0868|M.smegmatis_MC2_155 GRGGTSWVQAGYGPTTGGKASGTAKAGHGGKASDGGKGGNGGDALVMAAG Mflv_1516|M.gilvum_PYR-GCK ------------------------SAWADGKVGKGGVGGNGG-------- Mvan_5240|M.vanbaalenii_PYR-1 ------------------------ADSANGNAT-GGSGGRGG-------- MAB_0321c|M.abscessus_ATCC_199 ---------------------------------KGGDG------------ TH_4332|M.thermoresistible__bu ---------------------------NGGNGGLGGVLRPGG-------- MAV_4827|M.avium_104 ------------------------VPQPPSPPQVGGTVPQSP-------- MLBr_01556|M.leprae_Br4923 ----------------KTRLLDTIRKANVREAEAGGITQHIGAYQVGVDL ** Mb1121|M.bovis_AF2122/97 ----------KGGSGLSGNANGGAGGDS---------------------- Rv1091|M.tuberculosis_H37Rv ----------KGGSGLSGNANGGAGGDS---------------------- MUL_4524|M.ulcerans_Agy99 -----------GNSALS--VPGSIGGDA---------------------- MMAR_4224|M.marinum_M ----------GGGNGLP---STGVGGDG---------------------- MSMEG_0868|M.smegmatis_MC2_155 ATGVATGNTAIGGNGGAASANGAVGGNGGFTNIAAIHGSITDSSATSGHG Mflv_1516|M.gilvum_PYR-GCK ---------------GSRADSG-SGGAG---------------------- Mvan_5240|M.vanbaalenii_PYR-1 ---------------LAHSNAGGTGGNG---------------------- MAB_0321c|M.abscessus_ATCC_199 -------------------DDCEFGRTG---------------------- TH_4332|M.thermoresistible__bu --------------LLSLLLPSGAASEP---------------------- MAV_4827|M.avium_104 ---------------PQHQTPPGEGTPP---------------------- MLBr_01556|M.leprae_Br4923 DGSERLITFIDTPGHEAFTAMRARGAKAT--------------------- . Mb1121|M.bovis_AF2122/97 -----GRGGTGG---------------------AGGEGGAAGLLVGTGGH Rv1091|M.tuberculosis_H37Rv -----GRGGTGG---------------------AGGEGGAAGLLVGTGGH MUL_4524|M.ulcerans_Agy99 -----GAGGTGG---------------------SAGK---SGLLFGAG-- MMAR_4224|M.marinum_M -----GDGGNGG---------------------TAGN---GGWLIGNG-- MSMEG_0868|M.smegmatis_MC2_155 GAAQGGNGGNGGNGWVQAYDPNGPAGTTIDKGKAAGGNGGDGGFNGTGGA Mflv_1516|M.gilvum_PYR-GCK --------GTGG----------------------------DGWGYEEAD- Mvan_5240|M.vanbaalenii_PYR-1 --------GNGG----------------------------DAEADDAGKT MAB_0321c|M.abscessus_ATCC_199 --------GNGG-------------------------------------- TH_4332|M.thermoresistible__bu ----------GG-------------------------------------- MAV_4827|M.avium_104 --KPDGPGNYGG-----------------------------GHVPTPG-- MLBr_01556|M.leprae_Br4923 DIAILVVAADDG------------------VMPQTVEAINHAQAADVPIV .* Mb1121|M.bovis_AF2122/97 GGDGGAGGAAVKGGDGGAAAGTGIAGAGGRGGAGGSGG----SGGDGGGG Rv1091|M.tuberculosis_H37Rv GGDGGAGGAAVKGGDGGAAAGTGIAGAGGRGGAGGSGG----SGGDGGGG MUL_4524|M.ulcerans_Agy99 -------------------------GAGGQGGGGGTGG----DGGD---- MMAR_4224|M.marinum_M -------------------------GTGGQGGAGFAGG----TGADNVSA MSMEG_0868|M.smegmatis_MC2_155 TGGRGGDGAGASVWKANGQHSTGQTDTGGNGGRGGDGGTFVNAGANGNGG Mflv_1516|M.gilvum_PYR-GCK -------------------------AQGGNGGAGGLT------------- Mvan_5240|M.vanbaalenii_PYR-1 -------------------------AKGGNGGAGGTSG------------ MAB_0321c|M.abscessus_ATCC_199 --------------------------TGGRGGDGNFAG------------ TH_4332|M.thermoresistible__bu ------------------------LFTGGNGGNGGLAIAN---------- MAV_4827|M.avium_104 --------------------------AGGSGGSGGGHVP----------- MLBr_01556|M.leprae_Br4923 VAVNKIDKEGADPAKIRGQLTEYGLVAEDFGGDTMFIDISAKVGTNIEAL . ** Mb1121|M.bovis_AF2122/97 AAGPAGWLFGDGGAGGNGGAAAAGGAGGQAGG------------------ Rv1091|M.tuberculosis_H37Rv AAGPAGWLFGDGGAGGNGGAAAAGGAGGQAGG------------------ MUL_4524|M.ulcerans_Agy99 ------------CAGAN--------------------------------- MMAR_4224|M.marinum_M GR--------PGGAGGTGGIGAGGGNAGLIG------------------- MSMEG_0868|M.smegmatis_MC2_155 AGGAGGVSEGEGGTGGHGGDGGRGGDGALGGNGGTGGVGLGNGGKGGNGG Mflv_1516|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5240|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_0321c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4332|M.thermoresistible__bu -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 LEAVLLTADAALDLRANSGMEAQGVAIEAHLDRGRGPVATVLVQRG---- Mb1121|M.bovis_AF2122/97 ---------------GGGNGGNGGN---------------GGNGGNGGNG Rv1091|M.tuberculosis_H37Rv ---------------GGGNGGNGGN---------------GGNGGNGGNG MUL_4524|M.ulcerans_Agy99 ------------------IGGDGGA---------------GGAGGLGGNG MMAR_4224|M.marinum_M ---------------TGGSGGNGGM---------------GGHGGDSGYG MSMEG_0868|M.smegmatis_MC2_155 NGGNGGTYVDPSHTGAGGNGGNGGAGRIRVNNGTATGTATGGNGGNGGNG Mflv_1516|M.gilvum_PYR-GCK -------------------GGRGGH----------------GGAAESLNG Mvan_5240|M.vanbaalenii_PYR-1 ----------------TGQGGSGGN----------------GGNAVGDDA MAB_0321c|M.abscessus_ATCC_199 ------------------TGGNGGA-----------------ILVKCQHD TH_4332|M.thermoresistible__bu ----------------HWVGITDGVP---------------GPDDDAVSS MAV_4827|M.avium_104 ---------------TPGAGGSGGS---------------GGGHVPTPGT MLBr_01556|M.leprae_Br4923 -------------TLRIGDSVVAGDAYGRVRRMVDEHGVDIEAALPSSPV . * Mb1121|M.bovis_AF2122/97 ATGGWLYGNGGAGGQGATAGAGGAGANGVSSTNGG--------------- Rv1091|M.tuberculosis_H37Rv ATGGWLYGNGGAGGQGATAGAGGAGANGVSSTNGGG-------------- MUL_4524|M.ulcerans_Agy99 TDGGWLYGNGG--------------------------------------- MMAR_4224|M.marinum_M DQTGGQGGNGGMGGAG---------------------------------- MSMEG_0868|M.smegmatis_MC2_155 DADGHRGGKGGDGGEALIRATVIGSNASGTATGGDGGNGGTLGATNGTGG Mflv_1516|M.gilvum_PYR-GCK DATGGNGGNGG--------------------------------------- Mvan_5240|M.vanbaalenii_PYR-1 HAVGGSGGAGG--------------------------------------- MAB_0321c|M.abscessus_ATCC_199 LSLGTHPMDVS--------------------------------------- TH_4332|M.thermoresistible__bu SAYGGHGGHGAG-------------------------------------- MAV_4827|M.avium_104 GGPGGTGGSGGG-------------------------------------- MLBr_01556|M.leprae_Br4923 QVIGFTSVPGAGDNFLVVDEDRIARQIADRRSARKR-------------- * . Mb1121|M.bovis_AF2122/97 ------------------GNGGIGGTGGSGGAGGNAGLLGVGGAGGHGAS Rv1091|M.tuberculosis_H37Rv ----------------TGGNGGIGGTGGSGGAGGNAGLLGVGGAGGHGAS MUL_4524|M.ulcerans_Agy99 -------------------------------------------------- MMAR_4224|M.marinum_M -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 AATIVAYNVVQANPQASGTATDGHGGSGINGGHGGNGGQGTIEANGPSAV Mflv_1516|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_5240|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_0321c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4332|M.thermoresistible__bu -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 ----------------------------------NALAARSRKRISLEDL Mb1121|M.bovis_AF2122/97 GGAGDRGGAGGTGFISSDGGAGGD--------------------GGDGG- Rv1091|M.tuberculosis_H37Rv GGAGDRGGAGGTGFISSDGGAGGD--------------------GGDGG- MUL_4524|M.ulcerans_Agy99 ------------------GGAGGQ--------------------GGDGG- MMAR_4224|M.marinum_M ------GAAGNGGLLLGSGSRGGD--------------------GGDGG- MSMEG_0868|M.smegmatis_MC2_155 ASGIGAGGNGGDGIDGGLGGNGGDGVVNTTANAANPGSATGTATGGDGGK Mflv_1516|M.gilvum_PYR-GCK ------------GARV--VGDGGD--------------------GGDGG- Mvan_5240|M.vanbaalenii_PYR-1 ------------GVRLGTGGDGGD--------------------GGDAV- MAB_0321c|M.abscessus_ATCC_199 ------------------AGTGGN--------------------GGIGG- TH_4332|M.thermoresistible__bu ------------------PGSGGN-------------------------- MAV_4827|M.avium_104 --------------HVPTPGAGTP--------------------GGSGG- MLBr_01556|M.leprae_Br4923 DSALKETSQLNLILKGDNAGTVEALEEALMGIQVDDEVALRVIDRGVGGI . Mb1121|M.bovis_AF2122/97 ------NGGAGGTGGLLFGAGGNGGPGGSGGAADIGGNGGAGNGGGTDGN Rv1091|M.tuberculosis_H37Rv ------NGGAGGTGGLLFGAGGNGGPGGSGGAADIGGNGGAGNGGGTDGN MUL_4524|M.ulcerans_Agy99 ------HGGS---------------------------------------- MMAR_4224|M.marinum_M ------NGGEGR-------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 ATGTASQGGNGGPSWVQSGYGSTLGGNATGTATAGKGGEASNGGVAGNGG Mflv_1516|M.gilvum_PYR-GCK -----YGWGG---------------------------------------- Mvan_5240|M.vanbaalenii_PYR-1 -----SEDGN---------------------------------------- MAB_0321c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4332|M.thermoresistible__bu -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 TETNVNLASASDAIIIGFNVRAEG-------------------------- Mb1121|M.bovis_AF2122/97 GGNGGSGGGAGSGGDGGGAGGNGAWLFGNGGAGGGGGKGGNGAGGGLGGG Rv1091|M.tuberculosis_H37Rv GGNGGSGGGAGSGGDGGGAGGNGAWLFGNGGAGGGGGKGGNGAGGGLGGG MUL_4524|M.ulcerans_Agy99 -------------------------------------------------- MMAR_4224|M.marinum_M -------------------------------------------------G MSMEG_0868|M.smegmatis_MC2_155 NALVMAAGTTGVATGNTATGGDGGAATTAGATGGAGGFSNIAAIHGAITD Mflv_1516|M.gilvum_PYR-GCK -------------------------------------------------V Mvan_5240|M.vanbaalenii_PYR-1 -------------------------------------------------A MAB_0321c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4332|M.thermoresistible__bu -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------G MLBr_01556|M.leprae_Br4923 -------------------------------------------------K Mb1121|M.bovis_AF2122/97 SFGLPGLNGSG---------------------------------GDGGDG Rv1091|M.tuberculosis_H37Rv SFGLPGLNGSG---------------------------------GDGGDG MUL_4524|M.ulcerans_Agy99 PVGFDGKSGVG---------------------------------GDGGDG MMAR_4224|M.marinum_M GFSVP-QHGVG---------------------------------GQGGTG MSMEG_0868|M.smegmatis_MC2_155 STAISGHGGAGNGGNGGKGADGWVQAYDPAGPVGSKIANSSAVAGNGGDG Mflv_1516|M.gilvum_PYR-GCK PDEEGDPVGTGN--------------------------------GKGGNG Mvan_5240|M.vanbaalenii_PYR-1 TGGKGGDGGSVD--------------------------------LTGGGG MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------GGGGGG TH_4332|M.thermoresistible__bu ----------------------------------------------GGSA MAV_4827|M.avium_104 HLPFPGAGS-----------------------------------TPGGSG MLBr_01556|M.leprae_Br4923 ATELASREGVEIR--------------------------YYLVIYQAIDD . Mb1121|M.bovis_AF2122/97 GNGAPGGVLYGNGGAGGQGSSGGIGGPGAT--GGAGGKGGDGGDAQLIGD Rv1091|M.tuberculosis_H37Rv GNGAPGGVLYGNGGAGGQGSSGGIGGPGAT--GGAGGKGGDGGDAQLIGD MUL_4524|M.ulcerans_Agy99 GN------------------------------------------ARIIGN MMAR_4224|M.marinum_M GNGSDGGWLYGDGGAGGAGGNGGFGGSGVQ--NGAGGDAGSGGDSRLIGD MSMEG_0868|M.smegmatis_MC2_155 GVNGTGGASGGDGGNGGNTSVWKSGGQTADGEHNTGGNGGNGGDGSEPGP Mflv_1516|M.gilvum_PYR-GCK GAGGNGGVAVGN-----------------------GGNGGIGGDGYNETG Mvan_5240|M.vanbaalenii_PYR-1 GAGGEGGDADGDEKA-------------------TGGSGGSGGTGGLGGD MAB_0321c|M.abscessus_ATCC_199 SVGANG-----------------------------ATTGVFSSSSDCSGP TH_4332|M.thermoresistible__bu VANSLGN--------------------------AIAGNGGDAGRFVLIGP MAV_4827|M.avium_104 GGHLPTP-----------------------------GAGTPGGGLGGFGG MLBr_01556|M.leprae_Br4923 IEKALRGMLKPIYEENQLGRAEIRALFRSSKVGIIAGCIISSGVVRRNAK Mb1121|M.bovis_AF2122/97 GG---NGGNGGAGGTG-GTPGPGGPGGSGGLGG--LLFGQTGTAGVSP-- Rv1091|M.tuberculosis_H37Rv GG---NGGNGGAGGTG-GTPGPGGPGGSGGLGG--LLFGQTGTAGVSP-- MUL_4524|M.ulcerans_Agy99 GG---NGGNGGNGGVG-STDGD---GGQGGAAG--LLFGQPGSMGT---- MMAR_4224|M.marinum_M GG---AAG---AGGTG-APPGA---DGHSGADG--LLSAALGA------- MSMEG_0868|M.smegmatis_MC2_155 GGNG-AGGAGGNGGTGGTTAGGSGNGGNGGNGGNGGADGTPGTAGTTGAN Mflv_1516|M.gilvum_PYR-GCK GTKTPVAGKGGPGGAGGAIGSDGDAGADGETETSSGSSGSAGSADSDD-- Mvan_5240|M.vanbaalenii_PYR-1 GGAGGDGGDAVADDEGGATAGSGGDGGFGGTDGDDGSASDGADAPATD-- MAB_0321c|M.abscessus_ATCC_199 GP---QPNPGSPGDPGTSVAVS---GAQGNPGQAQFLIVP---------- TH_4332|M.thermoresistible__bu GG---NGGNGGTGLXXXPRPRRRRNHRRTRRRPNGRRPRPPPGR------ MAV_4827|M.avium_104 GHAP-APGGGLGGGGGHAPAPGGGLGGFGGGHSGGGLGGLGGGHK----- MLBr_01556|M.leprae_Br4923 VRLLRDNIVVTDNLTVTSLRREKDDVTEVREGFECGMTLGYSDIKEGDVI . Mb1121|M.bovis_AF2122/97 ----------- Rv1091|M.tuberculosis_H37Rv ----------- MUL_4524|M.ulcerans_Agy99 ----------- MMAR_4224|M.marinum_M ----------- MSMEG_0868|M.smegmatis_MC2_155 NP--------- Mflv_1516|M.gilvum_PYR-GCK ----------- Mvan_5240|M.vanbaalenii_PYR-1 ----------- MAB_0321c|M.abscessus_ATCC_199 ----------- TH_4332|M.thermoresistible__bu ----------- MAV_4827|M.avium_104 ----------- MLBr_01556|M.leprae_Br4923 ESYELVEKQRA