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M. marinum M MMAR_2709 (-)

annotation: PE-PGRS family protein, PE_PGRS34_1
coordinates: 3305630 - 3307195
length: 521

SFVVAAPEMVQAAASDIASIGSTINMANVAATAPTTAVLAAGADEVSAVIAALFAAHGQAYQTLSAQAAQ
FHDQFVAAMTSAAGAYSGAEAANVSPLQSLLDAANGETMAMLGRPLIGNGADGAPGQAGADGGLLFGNGG
NGGSGLAGQAGGVGGAAGLIGNGGNGGAGGAGSNGLAGGSGGAGGWLIGNGGNGGVGGIGSAAVGNGGSG
GAGGAAVGLFGNGGIGGAGGGAEGLNGGAGGVGGIGGKLYGDGGAGGIGGMGAADPSAAGGAGGAGGSAV
GWFGDGGAGGAGGPVVPTAALGGLGGAGGAGGNGGQLWGDGGAGGLGAFGQHGGGAGGAGGNAGMVGNGG
DGGTALGLAHGGDGGTGGTLIGNGGAGGGATMSDAGDGGDAVGLIGSGGAGGIGGAALAGGTGGTGGDGG
HGAKLLGNGGAGGAGGAAGGGLGNGGNGGNGGEAALIGNGGAGGDAGTSGSSRNFGDGGNGGDAQLIGNG
GNGGRGGVNGTGGTGGNGGTVAGANGTDGP*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_2709--100% (521)PE-PGRS family protein, PE_PGRS34_1
M. marinum MMMAR_0299-e-15556.52% (575) PE-PGRS family protein, PE_PGRS1
M. marinum MMMAR_4224-e-15253.52% (596) PE-PGRS family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0545PE_PGRS6a1e-15755.12% (586) hypothetical protein Mb0545
M. gilvum PYR-GCKMflv_5091-2e-9248.02% (454) triple helix repeat-containing collagen
M. tuberculosis H37RvRv1840cPE_PGRS341e-17361.75% (536) PE-PGRS family protein
M. leprae Br4923MLBr_01183-8e-1232.61% (92) hypothetical protein MLBr_01183
M. abscessus ATCC 19977MAB_4284c-2e-4534.19% (468) hypothetical protein MAB_4284c
M. avium 104MAV_4827-5e-2239.04% (187) hypothetical protein MAV_4827
M. smegmatis MC2 155MSMEG_0868-3e-8043.14% (503) hypothetical protein MSMEG_0868
M. thermoresistible (build 8)TH_3810-2e-3739.53% (301) PUTATIVE -
M. ulcerans Agy99MUL_3056-1e-16356.23% (546) PE-PGRS family protein
M. vanbaalenii PYR-1Mvan_1264-2e-8843.64% (550) triple helix repeat-containing collagen

CLUSTAL 2.0.9 multiple sequence alignment


Rv1840c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_3056|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2709|M.marinum_M               --------------------------------------------------
Mb0545|M.bovis_AF2122/97            --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155      MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv1840c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_3056|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2709|M.marinum_M               --------------------------------------------------
Mb0545|M.bovis_AF2122/97            --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1       -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155      PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv1840c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_3056|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2709|M.marinum_M               --------------------------------------------------
Mb0545|M.bovis_AF2122/97            --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1       ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155      SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv1840c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_3056|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2709|M.marinum_M               --------------------------------------------------
Mb0545|M.bovis_AF2122/97            --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1       ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155      PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------------------------------------
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv1840c|M.tuberculosis_H37Rv        ------------------------------------MSFVVAAPEVVVAA
MUL_3056|M.ulcerans_Agy99           ------------------------------------MSFVVAAPDAVTAA
MMAR_2709|M.marinum_M               ------------------------------------MSFVVAAPEMVQAA
Mb0545|M.bovis_AF2122/97            ------------------------------------MSNLLVTPELVAAA
Mflv_5091|M.gilvum_PYR-GCK          S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1       S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155      TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          -----------------------------------MPLFLNAEPQALTAA
MAB_4284c|M.abscessus_ATCC_199      ------------------------------------MSIIDFILNLFRDP
MAV_4827|M.avium_104                --------------------------------MNIVLGVSMAPSSIQMVV
                                                                                      

Rv1840c|M.tuberculosis_H37Rv        ASDLAGIGSAIGAANAAAAVPTMGVLAAGADEVSAAVADLFGAHAQAYQA
MUL_3056|M.ulcerans_Agy99           VQDLASIGSAINVANAAAATPTTGALAAAADEVSAAVAALFDGHAQAYQL
MMAR_2709|M.marinum_M               ASDIASIGSTINMANVAATAPTTAVLAAGADEVSAVIAALFAAHGQAYQT
Mb0545|M.bovis_AF2122/97            AADLAGIGSAIGAANAAAGAPTMALLAAGADEVSAAVAAVFSSYAQQYQA
Mflv_5091|M.gilvum_PYR-GCK          QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1       QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155      DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
TH_3810|M.thermoresistible__bu      ------------------------------------------------VD
MLBr_01183|M.leprae_Br4923          ANTLEGLSAATVASNAAAAQLTTEIAPPAADDVSILLAHFFSGHGRQYQA
MAB_4284c|M.abscessus_ATCC_199      VEAASYVADPEAALANAGLSAVSAAQVGAVMPVVAESVASNYGYQSQWVN
MAV_4827|M.avium_104                LEGEYADGATVEEDAIDVTGADDAATASAPDRVISAILGTREGAADAGLQ
                                                                                      

Rv1840c|M.tuberculosis_H37Rv        LSAQAALFHEQFVHAMTAGAGAY---AGAEAADA----AALDVLNGPFQA
MUL_3056|M.ulcerans_Agy99           IGAQAAEFHERFVRAMAAGAASY---ATAEAANASPLQAALDAVNAPAQA
MMAR_2709|M.marinum_M               LSAQAAQFHDQFVAAMTSAAGAY---SGAEAANVSPLQSLLDAANGETMA
Mb0545|M.bovis_AF2122/97            LSAAAAAFHDQFVRALAAGAGAY---AGAEAANVE--QQLLNAINAPTLA
Mflv_5091|M.gilvum_PYR-GCK          GNGGNGGNAGAFALFGNGGNGGN---GGVGVVGATGAVG--APGVAGATG
Mvan_1264|M.vanbaalenii_PYR-1       GDGGNGGDAGLFSLFGRGGNGGN---GGVGIAGATGAVG--APGVAGATG
MSMEG_0868|M.smegmatis_MC2_155      LDGGNGGSGG--LLMGIGGAGGA---GGVGADGTSAHVDGGTGGTGGTGG
TH_3810|M.thermoresistible__bu      GDGGSGGRTGLFSKLSRGGDGGD---GGLG-------------GNGGHGG
MLBr_01183|M.leprae_Br4923          HASQGATNHQDLIQSLLTSSSAY---AGTET--------------ANHDS
MAB_4284c|M.abscessus_ATCC_199      TGNPIHDLSGNLQNYYAAQPDGP---SILSPSLLSPRDNDFLSHNDTDFA
MAV_4827|M.avium_104                LSSIGVTWTDQLEAAALRDALAARRIDNVMLVSAFLAAAALAQNVGGAMG
                                                         .                           .

Rv1840c|M.tuberculosis_H37Rv        LFGRPLIGDGANGAP--GQPGGPGGLLYGNGGNGGNGG------------
MUL_3056|M.ulcerans_Agy99           LLGRPLIGDGADGAP--GQPGGAGGLLYGNGGSGGNGG------------
MMAR_2709|M.marinum_M               MLGRPLIGNGADGAP--GQAGADGGLLFGNGGNGGSGL------------
Mb0545|M.bovis_AF2122/97            LLGRPLIGNGADGAAGTGQAGGAGGLLYGNGGNGGSGA------------
Mflv_5091|M.gilvum_PYR-GCK          ATGVTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG------------
Mvan_1264|M.vanbaalenii_PYR-1       ATGVTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG------------
MSMEG_0868|M.smegmatis_MC2_155      GTGGTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGP
TH_3810|M.thermoresistible__bu      GTGIIS--------------------LLSLAGNGGNGG------------
MLBr_01183|M.leprae_Br4923          L-------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      SHNPIASGNQVMSPSGNVDSFNRGPLLDLSFGDLQFGNRDTTAIGDGAVA
MAV_4827|M.avium_104                YERTAVLLVEPDTATLAVVETSDGSIPDVYKQQIRAESYGDAAGQLSAMV
                                                                                      

Rv1840c|M.tuberculosis_H37Rv        --IGQPGGAGGDAGLIGNGG------------------------------
MUL_3056|M.ulcerans_Agy99           --IGQAGGAGGDAGLIGNGG------------------------------
MMAR_2709|M.marinum_M               --AGQAGGVGGAAGLIGNGG------------------------------
Mb0545|M.bovis_AF2122/97            --AGQAGGAGGAAGLIGHGG------------------------------
Mflv_5091|M.gilvum_PYR-GCK          --AVGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG-------------
Mvan_1264|M.vanbaalenii_PYR-1       --AVGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG-------------
MSMEG_0868|M.smegmatis_MC2_155      NVTVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTV
TH_3810|M.thermoresistible__bu      ---NGYRTTDNNALDGGHGG------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      VGGSNSGPIASGQGSTAVNG------------------------------
MAV_4827|M.avium_104                AGLEKLESLPGGLLLVGSGVDVAP--------------------------
                                                                                      

Rv1840c|M.tuberculosis_H37Rv        ---------------------------------------------NGGIG
MUL_3056|M.ulcerans_Agy99           ---------------------------------------------SGGIG
MMAR_2709|M.marinum_M               ---------------------------------------------NGGAG
Mb0545|M.bovis_AF2122/97            ---------------------------------------------TGGVG
Mflv_5091|M.gilvum_PYR-GCK          ---AVGAAGAAG------TVGTAGATGGTG---------------TGANG
Mvan_1264|M.vanbaalenii_PYR-1       ---AIGTAGVAG------AAGTAGATGGTG---------------VGGNG
MSMEG_0868|M.smegmatis_MC2_155      DGHAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDG
TH_3810|M.thermoresistible__bu      ---------------------------------------------NGGNV
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ----------------------------------DVRDSNIINADHGSNV
MAV_4827|M.avium_104                ----------------------------------LKQVLQTTTFLDVSVA
                                                                                      

Rv1840c|M.tuberculosis_H37Rv        GPGATGLAGGAGGVG------------GLLFGDGGNGGAGGLGTGPVGAT
MUL_3056|M.ulcerans_Agy99           GPDSTGLPGGAGGAG------------GWLLGDGGNGGIGGAGTG-IGGA
MMAR_2709|M.marinum_M               GAGSNGLAGGSGGAG------------GWLIGNGGNGGVGGIGSAAVGNG
Mb0545|M.bovis_AF2122/97            G---TGAAGGAGGTG------------GWLFGNGGAGGTGGAVTG-VSTT
Mflv_5091|M.gilvum_PYR-GCK          GAGGVGGVGGTGAAG--------------AAGGAGGLGETGTTGGAGGVG
Mvan_1264|M.vanbaalenii_PYR-1       GAGQAGGIGGTGAAG--------------AAGQAGTAGETGVTGGVGGIG
MSMEG_0868|M.smegmatis_MC2_155      GHSTGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMG
TH_3810|M.thermoresistible__bu      GFFSLFNLGG--------------------AGGWGGSGVDG---------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      GVDQSQTRVGGDYTNVSGHGSADIDKSVTVVDDHSQRNTTNINDSFNTDR
MAV_4827|M.avium_104                EEPETALARGAALAAANAPLFASSTAALAYAQDPGTGAVDQYSLPDYLYV
                                                                                      

Rv1840c|M.tuberculosis_H37Rv        GGIGGPGGAAVGLFGHGGAGGAGGLGKAGFAGGAG---------------
MUL_3056|M.ulcerans_Agy99           GGSGGQGGAAAWLFGSGGTGGAGGFGNSG-TGGPG---------------
MMAR_2709|M.marinum_M               G-SGGAGGAAVGLFGNGGIGGAGG-GAEGLNGGAG---------------
Mb0545|M.bovis_AF2122/97            GGPGGHGGDAG-LYGFGGAGGAGGFGQSGAAGGAG---------------
Mflv_5091|M.gilvum_PYR-GCK          GQ--GTAGGTGGVGGIGGAGSTGAVGGVGGKG----IQGGQG--------
Mvan_1264|M.vanbaalenii_PYR-1       GQ--GTEGGTGGVGGVGGVGATGGAGGVGGKG----IQGGQG--------
MSMEG_0868|M.smegmatis_MC2_155      EIYSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKAS
TH_3810|M.thermoresistible__bu      ------------VDVVGGNP------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      STNIGSGNTTNTEIGSHNQANIGTSTSAGGSAAVG---------------
MAV_4827|M.avium_104                PVDPEPGDDELAYSAVGEEDAESPTVVIEKLFLPE---------------
                                                                                      

Rv1840c|M.tuberculosis_H37Rv        -----------GTGGTGG---------------------------LLYGN
MUL_3056|M.ulcerans_Agy99           -----------GAGGTGG---------------------------LLIGN
MMAR_2709|M.marinum_M               -----------GVGGIGG---------------------------KLYGD
Mb0545|M.bovis_AF2122/97            -----------GAGGAGG---------------------------WLYGD
Mflv_5091|M.gilvum_PYR-GCK          -----LQGGKGGDGGAGGKGGDADSMGS------------------AGAT
Mvan_1264|M.vanbaalenii_PYR-1       -----LQGGQGGDGGTGGTGGDATSMGE------------------AGAT
MSMEG_0868|M.smegmatis_MC2_155      GTAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASAN
TH_3810|M.thermoresistible__bu      ------------DGGTPG------------------------------AH
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -----------GNAGLAGNAG-------------------------LAGN
MAV_4827|M.avium_104                ------------DSEPRRRP-------------------------VLLVG
                                                                                      

Rv1840c|M.tuberculosis_H37Rv        GGNGGNVPSGAAD-------------------------------------
MUL_3056|M.ulcerans_Agy99           GGNGGYDIQGGAF-------------------------------------
MMAR_2709|M.marinum_M               GGAGGIGGMGAADPSA----------------------------------
Mb0545|M.bovis_AF2122/97            GGDGGAGGNGGNESGTG---------------------------------
Mflv_5091|M.gilvum_PYR-GCK          GGKGGNGGNGGRGGLFG---------------KGGNAGNGAD--------
Mvan_1264|M.vanbaalenii_PYR-1       GGKGGNGGNGGRGSLFG---------------RGGNAGNGGN--------
MSMEG_0868|M.smegmatis_MC2_155      GAVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDP
TH_3810|M.thermoresistible__bu      GESHTPGVYTDRQ-------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      AGLAGNAGLAGNAGLAG---------------------------------
MAV_4827|M.avium_104                SGLAVVGISAVLALEIALAIG-----------------------------
                                                                                      

Rv1840c|M.tuberculosis_H37Rv        --------------------GGAGGDAR-LIGNGGDGGS-----------
MUL_3056|M.ulcerans_Agy99           --------------------GGDGGNAR-LIGNGGDGGV-----------
MMAR_2709|M.marinum_M               ----------------AGGAGGAGGSAVGWFGDGGAGGAG----------
Mb0545|M.bovis_AF2122/97            -------------VSGVGGVGGAGGAGGLLFGNGGDGGVG----------
Mflv_5091|M.gilvum_PYR-GCK          --------------GGTGGAGGAGGTGG-TGGAGGTGG------------
Mvan_1264|M.vanbaalenii_PYR-1       --------------GGTGGNGGNGGTGG-TGGNGGTGG------------
MSMEG_0868|M.smegmatis_MC2_155      NGPAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHS
TH_3810|M.thermoresistible__bu      ------------------GEDGEDGTGTGIGGRGGNGG------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -------------NAGLAGNAGLAGNAGLAGNAGLAGNAG----------
MAV_4827|M.avium_104                --------------IRTTGTVALQPTPNQHLIVPTEQAPAP---------
                                                                                      

Rv1840c|M.tuberculosis_H37Rv        -----------------VGAAPTGIGNGGNGGNGGWLYGDGGSGGSTLQG
MUL_3056|M.ulcerans_Agy99           -----------------EAGGPG--TTGGDGGNGGWLLGNGGNGAADGGG
MMAR_2709|M.marinum_M               ---------GPV---VPTAALGGLGGAGGAGGNGGQLWGDGGAGGLGAFG
Mb0545|M.bovis_AF2122/97            ---------GDGGDGSSTQDSGGDGGAGGAGGAGGWLLGNGGAGGAGGAA
Mflv_5091|M.gilvum_PYR-GCK          -----TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTG
Mvan_1264|M.vanbaalenii_PYR-1       -----TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTG
MSMEG_0868|M.smegmatis_MC2_155      TGQTDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGDG
TH_3810|M.thermoresistible__bu      ----SSSGTHPMAEDG--------EHVKALDGRPGLD---GGNGSHGGNG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -----LAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAG
MAV_4827|M.avium_104                ------PPVQASAPQPKISVPEPVAAPKPLSPPVAAPLPAAPPPAAPPLP
                                                                                      

Rv1840c|M.tuberculosis_H37Rv        FS-----------------------DG--------GTGGNAGMFGDGGNG
MUL_3056|M.ulcerans_Agy99           AGSAAGAGGNAGLIGNGGHGGLEHIDGTGGAGSIAGAGGDAGLFGSGGNG
MMAR_2709|M.marinum_M               QHG----------------------GGAG------GAGGNAGMVGNGGDG
Mb0545|M.bovis_AF2122/97            SIKVAT-------------------GGLG------GDGGDAGLFGFGGDG
Mflv_5091|M.gilvum_PYR-GCK          GKGGTG--------------GTGGAGGTG---------GDGGTGGTGGTG
Mvan_1264|M.vanbaalenii_PYR-1       GKGGTG--------------GTGGDGGTG---------GTGGTGGTGGTG
MSMEG_0868|M.smegmatis_MC2_155      GRGGDG--------------ALGGNGGTGG-----VGLGNGGKGGNGGNG
TH_3810|M.thermoresistible__bu      GHGGRG--------------GFLGIGGSG------------GWGGHGGNG
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      NAGLAG--------------NAGLAGNAG-------LAGNAGLAGNAAVA
MAV_4827|M.avium_104                EAPPIP--------------AAPPVVPVPVVVPPVPVPVPVRIPVPDPVS
                                                                                      

Rv1840c|M.tuberculosis_H37Rv        G---------FSFFDGNGGDGGTG-----------GTLIGNGGDG-----
MUL_3056|M.ulcerans_Agy99           G---------FNGYQGVGGAGGAG-----------GKLFGDGGDG-----
MMAR_2709|M.marinum_M               G---------TALGLAHGGDGGTG-----------GTLIGNGGAG-----
Mb0545|M.bovis_AF2122/97            GWGGRGVDARFGAAGGAAGAGGAG-----------GWLYGDGGAGGVGGV
Mflv_5091|M.gilvum_PYR-GCK          GTG---------GTGGTGGTGGAG-----------DGTGGTGGTGG----
Mvan_1264|M.vanbaalenii_PYR-1       GTG---------GTGGTGGTGGAG-----------DGLGGTGGTGG----
MSMEG_0868|M.smegmatis_MC2_155      GNGGTYVDPSHTGAGGNGGNGGAGRIRVNNGTATGTATGGNGGNGGNGDA
TH_3810|M.thermoresistible__bu      GD-----------TDADGGNGGDG---------------GNGGSAG----
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      GNAAVAGNAAVAGNAAVGGVLNTG---------VSGAIGGSSHVGG--AI
MAV_4827|M.avium_104                PPQLLAPPRLSVPQPVQPPVRVPQ----------PPSPPQVGGTVPQSPP
                                                                                      

Rv1840c|M.tuberculosis_H37Rv        GNSVQTDGFLR-----------------GHGGDGGNAVGLIGNGGAG---
MUL_3056|M.ulcerans_Agy99           GDCAESNGGI------------------GSGGRGGSAVGLIGNGGAG---
MMAR_2709|M.marinum_M               GGATMS-----------------------DAGDGGDAVGLIGSGGAG---
Mb0545|M.bovis_AF2122/97            GGAVFSLSSGDG----------------GAGGAGGGGGWLFGNGGDG---
Mflv_5091|M.gilvum_PYR-GCK          TGGQGGQGGQGG-----------------TGGTGGQGG-LGGGGGTG---
Mvan_1264|M.vanbaalenii_PYR-1       TGGFGGQGGQGG-----------------TGGTGGQGG-LGGVGGTG---
MSMEG_0868|M.smegmatis_MC2_155      DGHRGGKGGDGGEALIRATVIGSNASGTATGGDGGNGGTLGATNGTGGAA
TH_3810|M.thermoresistible__bu      -----------------------------RGGTGGLRGVFGINGGNG---
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      NESLGGSGSVGG------------STAVGGGAHTGVGGGVSTGVGVG---
MAV_4827|M.avium_104                QHQTPPGEGTPP----------------KPDGPGNYGGGHVPTPGAG---
                                                                                      

Rv1840c|M.tuberculosis_H37Rv        ---------------------GAGSAGTGVFAPGGGSGGNG---------
MUL_3056|M.ulcerans_Agy99           ---------------------GVG--GVGRNANAGGSGGSG---------
MMAR_2709|M.marinum_M               ---------------------GIG--GAALAGGTGGTGGDG---------
Mb0545|M.bovis_AF2122/97            ---------------------GAGGGGGGRFGSGSGAGGDGAVG------
Mflv_5091|M.gilvum_PYR-GCK          --------------------GQGGTGGTGGQGGTGGTGGTGGTG------
Mvan_1264|M.vanbaalenii_PYR-1       --------------------GTGGTGGTGGQGGTGGTGGTGGTG------
MSMEG_0868|M.smegmatis_MC2_155      TIVAYNVVQANPQASGTATDGHGGSGINGGHGGNGGQGTIEANGPSAVAS
TH_3810|M.thermoresistible__bu      ---------------------RAGLGGRGXXXXGGGVGAAVRSG------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      --------------------SHVGGGISESLGGSGSVGGSTAVG------
MAV_4827|M.avium_104                ----------------------GSGGSGGGHVPTPGAGGSGGSG------
                                                                                      

Rv1840c|M.tuberculosis_H37Rv        -------GNGALLVGNGGAGGSGGPTQIPSVAV-PVTGAGGTGGNG----
MUL_3056|M.ulcerans_Agy99           -------GNAAWLFGDGGAGGSGGSSD---------TAASGAGGNG----
MMAR_2709|M.marinum_M               -------GHGAKLLGNGGAGGAGGAAG-------GGLGNGGNGGNG----
Mb0545|M.bovis_AF2122/97            -----GAGGAGAWFGNGGAGGVGGGGGRGTTAIGGDGGAGGAGGAGG---
Mflv_5091|M.gilvum_PYR-GCK          --GTGGAGGDGGLGGLGGFGGSGGTGGQGGLGGPGGSTGGAGGAGG--QA
Mvan_1264|M.vanbaalenii_PYR-1       --GTGGAGGDGGLGGLGGFGGVGGTGGQGGQGGPGGSTGGAGGAGG--QA
MSMEG_0868|M.smegmatis_MC2_155      GIGAGGNGGDGIDGGLGGNGGDGVVNTTANAANPGSATGTATGGDGGKAT
TH_3810|M.thermoresistible__bu      ---------NGVFSGGGGTPSAGFGVPTTIQFPAGSCTSRAVSREG----
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ---------GGAHTGVGGGVSTGVGVGSHVGGGISESLGGSGSVGG----
MAV_4827|M.avium_104                -------GGHVPTPGTGGPGGTGGSGGGHVPTPGAGTPGGSGGGHLP---
                                                                                      

Rv1840c|M.tuberculosis_H37Rv        -----------------GTAGLIGNGGNGGAAGVSGDG-TPGTGGNGG--
MUL_3056|M.ulcerans_Agy99           -----------------GTAALIGNGGAGGDAGVSFAG-MAGPGGNGG--
MMAR_2709|M.marinum_M               -----------------GEAALIGNGGAGGDAGTSGSSRNFGDGGNGG--
Mb0545|M.bovis_AF2122/97            --------------WLYGDGGAGGAGGGGGRGGTGNDGGDGGDGGRGG--
Mflv_5091|M.gilvum_PYR-GCK          GTAGKGGLFG----GSGSAGKAGATGAAGASGGKGAQGATGAQGATG---
Mvan_1264|M.vanbaalenii_PYR-1       GVAGKGGLFG----GSGSAGTAGVTGASGASGGKGAQGATGAQGATG---
MSMEG_0868|M.smegmatis_MC2_155      GTASQGGNGGPSWVQSGYGSTLGGNATGTATAGKGGEASNGGVAGNGGNA
TH_3810|M.thermoresistible__bu      --------------------IMPSSRAASARAG-----------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -------------------STAVGGGAHTGVGGGVNTGVGVGSHVGGG--
MAV_4827|M.avium_104                ---------------FPGAGSTPGGSGGGHLPTPGAGTPGGGLGGFGGG-
                                                                                      

Rv1840c|M.tuberculosis_H37Rv        ----------YAQLIGDGGDGGPGDSGGPG--------------------
MUL_3056|M.ulcerans_Agy99           ----------DARLIGDGGDGG---RGAPG--------------------
MMAR_2709|M.marinum_M               ----------DAQLIGNGGNGGRGGVNGTG--------------------
Mb0545|M.bovis_AF2122/97            ----------DAQLLGNGGDGGAGGAGGPAGFGAS--------PGAGAAG
Mflv_5091|M.gilvum_PYR-GCK          ---AQGATG-ATGAAGKAGATGAAGAAGAAGSAG-----------TTGAQ
Mvan_1264|M.vanbaalenii_PYR-1       ---AQGATG-ATGASGAQGSAGSAGSAGVAGSAG-----------TTGAQ
MSMEG_0868|M.smegmatis_MC2_155      LVMAAGTTGVATGNTATGGDGGAATTAGATGGAGGFSNIAAIHGAITDST
TH_3810|M.thermoresistible__bu      ----------AACASSTSRSRRSFCCSRA---------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      ---------ISESLGGSGSVGGSTAVGGGAHTSAIN----------DALG
MAV_4827|M.avium_104                ----------HAPAPGGGLGGGGGHAPAPGGGLGG--------------F
                                                                                      

Rv1840c|M.tuberculosis_H37Rv        GSGGTGGTLAGQNGSPGG--------------------------------
MUL_3056|M.ulcerans_Agy99           GAGGMGGSLFGQDGSNGA--------------------------------
MMAR_2709|M.marinum_M               GTGGNGGTVAGANGTDGP--------------------------------
Mb0545|M.bovis_AF2122/97            GGGGAGGSLFGSPGTTGPHG------------------------------
Mflv_5091|M.gilvum_PYR-GCK          GSAGTNGA-NGANGSQGAAGKAGATGTTGATG--------AAGEDGDAGS
Mvan_1264|M.vanbaalenii_PYR-1       GSAGTNGA-NGANGSQGAAGKAGATGTTGATG--------AAGDAGDPGS
MSMEG_0868|M.smegmatis_MC2_155      AISGHGGAGNGGNGGKGADGWVQAYDPAGPVGSKIANSSAVAGNGGDGGV
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      GSGSVGGSTAVGGGAHTSAINESMN-------------------------
MAV_4827|M.avium_104                GGGHSGGGLGGLGGGHK---------------------------------
                                                                                      

Rv1840c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_3056|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2709|M.marinum_M               --------------------------------------------------
Mb0545|M.bovis_AF2122/97            --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          GGSG-INGGAGGAGG-----------AGGEGGEGGDGGKGGAGAE-----
Mvan_1264|M.vanbaalenii_PYR-1       EAVD-INGGAGGAGG-----------AGGEGGEGGAGGAGGDGSE-----
MSMEG_0868|M.smegmatis_MC2_155      NGTGGASGGDGGNGGNTSVWKSGGQTADGEHNTGGNGGNGGDGSEPGPGG
TH_3810|M.thermoresistible__bu      --------------------------------------------------
MLBr_01183|M.leprae_Br4923          --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      -------------------------------------------SSINASH
MAV_4827|M.avium_104                --------------------------------------------------
                                                                                      

Rv1840c|M.tuberculosis_H37Rv        -------------------------------------------------
MUL_3056|M.ulcerans_Agy99           -------------------------------------------------
MMAR_2709|M.marinum_M               -------------------------------------------------
Mb0545|M.bovis_AF2122/97            -------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          ---GGAGGGGGAGGSGAGGAG--GAGGSGGSGGSGGSGGSGGAAGDSDD
Mvan_1264|M.vanbaalenii_PYR-1       ---GGAGGSGGAGGSGTGGAG--GAGGSGGSGGSGGAGGSGGAAGDSD-
MSMEG_0868|M.smegmatis_MC2_155      NGAGGAGGNGGTGGTTAGGSGNGGNGGNGGNGGADGTPGTAGTTGANNP
TH_3810|M.thermoresistible__bu      -------------------------------------------------
MLBr_01183|M.leprae_Br4923          -------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199      SSSMNESFGSSMGSHGAAGTGFEAQGHAQGHASETAHTTLPGAEHH---
MAV_4827|M.avium_104                -------------------------------------------------