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MSFVVAAPEVVVAAASDLAGIGSAIGAANAAAAVPTMGVLAAGADEVSAAVADLFGAHAQAYQALSAQAA LFHEQFVHAMTAGAGAYAGAEAADAAALDVLNGPFQALFGRPLIGDGANGAPGQPGGPGGLLYGNGGNGG NGGIGQPGGAGGDAGLIGNGGNGGIGGPGATGLAGGAGGLGKAGFAGGAGGTGGTGGLLYGNGGNGGNVP SGAADGGAGGDARLIGNGGDGGSVGAAPTGIGNGGNGGNGGWLYGDGGSGGSTLQGFSDGGTGGNAGMFG DGGNGGFSFFDGNGGDGGTGGTLIGNGGDGGNSVQTDGFLRGHGGDGGNAVGLIGNGGAGGAGSAGTGVF APGGGSGGNGGNGALLVGNGGAGGSGGPTQIPSVAVPVTGAGGTGGNGGTAGLIGNGGNGGAAGVSGDGT PGTGGNGGYAQLIGDGGDGGPGDSGGPGGSGGTGGTLAGQNGSPGG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1871c | PE_PGRS34 | - | 100% (466) | PE-PGRS family protein |
| M. bovis AF2122 / 97 | Mb1849c | PE_PGRS33 | e-134 | 56.08% (510) | PE-PGRS family protein |
| M. bovis AF2122 / 97 | Mb2186c | PE_PGRS38 | e-134 | 54.83% (507) | hypothetical protein Mb2186c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_5091 | - | 1e-69 | 40.20% (490) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv1840c | PE_PGRS34 | 0.0 | 90.49% (515) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01183 | - | 2e-13 | 37.50% (96) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 9e-40 | 36.29% (350) | hypothetical protein MAB_4284c |
| M. marinum M | MMAR_2709 | - | 1e-142 | 53.86% (544) | PE-PGRS family protein, PE_PGRS34_1 |
| M. avium 104 | MAV_1346 | - | 1e-22 | 32.36% (275) | PE family protein |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 2e-62 | 39.95% (418) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_4332 | - | 1e-37 | 38.53% (327) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_3056 | - | 1e-160 | 57.77% (547) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_3867 | - | 2e-72 | 40.40% (495) | PE-PGRS family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1871c|M.bovis_AF2122/97 --------------------------------------------------
Rv1840c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3056|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2709|M.marinum_M --------------------------------------------------
TH_4332|M.thermoresistible__bu --------------------------------------------------
Mvan_3867|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mb1871c|M.bovis_AF2122/97 --------------------------------------------------
Rv1840c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3056|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2709|M.marinum_M --------------------------------------------------
TH_4332|M.thermoresistible__bu --------------------------------------------------
Mvan_3867|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mb1871c|M.bovis_AF2122/97 --------------------------------------------------
Rv1840c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3056|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2709|M.marinum_M --------------------------------------------------
TH_4332|M.thermoresistible__bu --------------------------------------------------
Mvan_3867|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mb1871c|M.bovis_AF2122/97 --------------------------------------------------
Rv1840c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3056|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2709|M.marinum_M --------------------------------------------------
TH_4332|M.thermoresistible__bu --------------------------------------------------
Mvan_3867|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
MAB_4284c|M.abscessus_ATCC_199 ----------------------------------------MSIIDFILNL
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mb1871c|M.bovis_AF2122/97 --------------------------------------------------
Rv1840c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3056|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2709|M.marinum_M --------------------------------------------------
TH_4332|M.thermoresistible__bu --------------------------------------------------
Mvan_3867|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
MAB_4284c|M.abscessus_ATCC_199 FR-----------------------DPVEAASYVADPEAALANAGLSAVS
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mb1871c|M.bovis_AF2122/97 --------------------------------------------------
Rv1840c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3056|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2709|M.marinum_M --------------------------------------------------
TH_4332|M.thermoresistible__bu --------------------------------------------------
Mvan_3867|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
MAB_4284c|M.abscessus_ATCC_199 AAQVGAVMPVVAESVASNYGYQSQWVNTGNPIHDLSGNLQNYYAAQPDGP
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mb1871c|M.bovis_AF2122/97 -----------MSFVVAAPEVVVAAASDLAGIGSAIGAANAAAAVPTMGV
Rv1840c|M.tuberculosis_H37Rv -----------MSFVVAAPEVVVAAASDLAGIGSAIGAANAAAAVPTMGV
MUL_3056|M.ulcerans_Agy99 -----------MSFVVAAPDAVTAAVQDLASIGSAINVANAAAATPTTGA
MMAR_2709|M.marinum_M -----------MSFVVAAPEMVQAAASDIASIGSTINMANVAATAPTTAV
TH_4332|M.thermoresistible__bu ------------------MPFITSGAAFVGGAAMLLAGPGGVSALEAAGS
Mvan_3867|M.vanbaalenii_PYR-1 ------------MPHPILATAMAVGIAATAGAGALGDAPPTVNVTANKHV
Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG
MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG
MAB_4284c|M.abscessus_ATCC_199 SILSPSLLSPRDNDFLSHNDTDFASHNPIASGNQVMSPSGNVDSFNRGPL
MLBr_01183|M.leprae_Br4923 ----------MPLFLNAEPQALTAAANTLEGLSAATVASNAAAAQLTTEI
MAV_1346|M.avium_104 ----------MS-FVTTRPEALLAVASMLEGLGSSMDAQNAAAAAPTTSI
.
Mb1871c|M.bovis_AF2122/97 LAAGADEVSAAVADLFGAHAQAYQALSAQAALFHEQ--------------
Rv1840c|M.tuberculosis_H37Rv LAAGADEVSAAVADLFGAHAQAYQALSAQAALFHEQ--------------
MUL_3056|M.ulcerans_Agy99 LAAAADEVSAAVAALFDGHAQAYQLIGAQAAEFHER--------------
MMAR_2709|M.marinum_M LAAGADEVSAVIAALFAAHGQAYQTLSAQAAQFHDQ--------------
TH_4332|M.thermoresistible__bu APR------TVEYEYSLVACDSTLPLMCEAGDSVG---------------
Mvan_3867|M.vanbaalenii_PYR-1 SATRLTAVVTPNALYSAAPASDVVVLGAHGSLAVGE-------------P
Mflv_5091|M.gilvum_PYR-GCK VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------A
MSMEG_0868|M.smegmatis_MC2_155 GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT
MAB_4284c|M.abscessus_ATCC_199 LDLSFGDLQFGNRDTTAIGDGAVAVGGSNSGPIASG--------------
MLBr_01183|M.leprae_Br4923 APPAADDVSILLAHFFSGHGRQYQAHASQGATNHQD--------------
MAV_1346|M.avium_104 APAAADEVSALQAAQFSAYGTWYQQVSAQAKAIHQT--------------
.
Mb1871c|M.bovis_AF2122/97 ---FVHAMTAGAGAYAGAEAADA----AALDVLNGPFQALFGRP------
Rv1840c|M.tuberculosis_H37Rv ---FVHAMTAGAGAYAGAEAADA----AALDVLNGPFQALFGRP------
MUL_3056|M.ulcerans_Agy99 ---FVRAMAAGAASYATAEAANASPLQAALDAVNAPAQALLGRP------
MMAR_2709|M.marinum_M ---FVAAMTSAAGAYSGAEAANVSPLQSLLDAANGETMAMLGRP------
TH_4332|M.thermoresistible__bu -------GLGGASHDRSAFSASALGMAS----------------------
Mvan_3867|M.vanbaalenii_PYR-1 RGVPQAGALAGASRAVPGGLELSTGLATSRVHPLPERVNTDIEM------
Mflv_5091|M.gilvum_PYR-GCK VG--SAGAAGEAGETGTWGNAGLPGKAGDAGGAG----AVGAAG---AAG
MSMEG_0868|M.smegmatis_MC2_155 VGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGH
MAB_4284c|M.abscessus_ATCC_199 QGSTAVNGDVRDSNIINADHGSNVGVDQSQTRVGGDYTNVSGHG------
MLBr_01183|M.leprae_Br4923 ---LIQSLLTSSSAYAGTETAN----------------------------
MAV_1346|M.avium_104 ---LVQNLDTNADSYGATEAANRVNTSAAALQGLAPNVIPNAAP------
Mb1871c|M.bovis_AF2122/97 --------------------------------------------------
Rv1840c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3056|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2709|M.marinum_M --------------------------------------------------
TH_4332|M.thermoresistible__bu --------------------------------------------------
Mvan_3867|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK TVGTAGATGGTG----TGANGGAGGVG-----GVGGTGAAGAAGGAG---
MSMEG_0868|M.smegmatis_MC2_155 AIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHS
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mb1871c|M.bovis_AF2122/97 ------------------------------LIGDGANGAPGQPGGPG---
Rv1840c|M.tuberculosis_H37Rv ------------------------------LIGDGANGAPGQPGGPG---
MUL_3056|M.ulcerans_Agy99 ------------------------------LIGDGADGAPGQPGGAG---
MMAR_2709|M.marinum_M ------------------------------LIGNGADGAPGQAGADG---
TH_4332|M.thermoresistible__bu -------------------------------FGPDWNPGGAFLGLIG---
Mvan_3867|M.vanbaalenii_PYR-1 -------------------------VSAPTTSGPALRLGRATTPSVG---
Mflv_5091|M.gilvum_PYR-GCK ---GLGETGTTG--------------GAGGVGGQGTAGGTGGVGGIG---
MSMEG_0868|M.smegmatis_MC2_155 TGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEIY
MAB_4284c|M.abscessus_ATCC_199 --------------------------SADIDKSVTVVDDHSQRNTTN---
MLBr_01183|M.leprae_Br4923 ------------------------------------------HDSL----
MAV_1346|M.avium_104 ----------------------------------AADPPPAGTTSLG---
Mb1871c|M.bovis_AF2122/97 --------------------------------------------------
Rv1840c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3056|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2709|M.marinum_M --------------------------------------------------
TH_4332|M.thermoresistible__bu -----------------------------------------PGG------
Mvan_3867|M.vanbaalenii_PYR-1 -----------------------------------------STGPAGAAA
Mflv_5091|M.gilvum_PYR-GCK --------------------GAGSTGAVGG-----------VGGKGIQGG
MSMEG_0868|M.smegmatis_MC2_155 SGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASGTA
MAB_4284c|M.abscessus_ATCC_199 ----------------------------------------INDSFNTDRS
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mb1871c|M.bovis_AF2122/97 ----GLLYGNGGNGGNGG-------------------------IGQPGGA
Rv1840c|M.tuberculosis_H37Rv ----GLLYGNGGNGGNGG-------------------------IGQPGGA
MUL_3056|M.ulcerans_Agy99 ----GLLYGNGGSGGNGG-------------------------IGQAGGA
MMAR_2709|M.marinum_M ----GLLFGNGGNGGSGL-------------------------AGQAGGV
TH_4332|M.thermoresistible__bu -----LLIGDG--LNGTDAYIDENG-----------------VFHEATR-
Mvan_3867|M.vanbaalenii_PYR-1 PGLFSLLIGNGDEPGENGGWLIGNG-----------------ADGGPGQD
Mflv_5091|M.gilvum_PYR-GCK QGLQGGKGGDGGAGGKGGDADSMGS------------------AGATGGK
MSMEG_0868|M.smegmatis_MC2_155 KAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANGAV
MAB_4284c|M.abscessus_ATCC_199 TNIGSGNTTNTEIGSHNQANIGTST-----------------SAGGSAAV
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 -----------------------------------------TSIGWAQNV
Mb1871c|M.bovis_AF2122/97 GGDAG---------------------------------------------
Rv1840c|M.tuberculosis_H37Rv GGDAG---------------------------------------------
MUL_3056|M.ulcerans_Agy99 GGDAG---------------------------------------------
MMAR_2709|M.marinum_M GGAAG---------------------------------------------
TH_4332|M.thermoresistible__bu GGNGG---------------------------------------------
Mvan_3867|M.vanbaalenii_PYR-1 GGRGG---------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GGNGGNGGRGGLFG---------------KGGNAGNG-------------
MSMEG_0868|M.smegmatis_MC2_155 GGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNGP
MAB_4284c|M.abscessus_ATCC_199 GGNAG---------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 GAAAS---------------------------------------------
Mb1871c|M.bovis_AF2122/97 ----------LIGNGGNGGIGGPGATGLAGGAG-----------------
Rv1840c|M.tuberculosis_H37Rv ----------LIGNGGNGGIGGPGATGLAGGAGGVGGLL-----------
MUL_3056|M.ulcerans_Agy99 ----------LIGNGGSGGIGGPDSTGLPGGAGGAGGWL-----------
MMAR_2709|M.marinum_M ----------LIGNGGNGGAGGAGSNGLAGGSGGAGGWL-----------
TH_4332|M.thermoresistible__bu ---------LLWGNGGKGGNGLDAGLYTVPDPDN----------------
Mvan_3867|M.vanbaalenii_PYR-1 ---------LLFGNGGRGGDALTSGGPAGRGGDAGLFG------------
Mflv_5091|M.gilvum_PYR-GCK ---------ADGGTGGAGGAGGTGG-TGGAGGTGG---------------
MSMEG_0868|M.smegmatis_MC2_155 AGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHSTGQ
MAB_4284c|M.abscessus_ATCC_199 ----------LAGNAGLAGNAGLAGNAGLAGNAGLAGN------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 ----------DFITLGEGQFAPVPGAAGIPNFNPGLTAAT---------T
Mb1871c|M.bovis_AF2122/97 ---------------------------------------------GLGKA
Rv1840c|M.tuberculosis_H37Rv --FGDGGNGGAGGLGTGPVGATGGIGGPGGAAVGLFGHGGAGGAGGLGKA
MUL_3056|M.ulcerans_Agy99 --LGDGGNGGIGGAGTG-IGGAGGSGGQGGAAAWLFGSGGTGGAGGFGNS
MMAR_2709|M.marinum_M --IGNGGNGGVGGIGSAAVGN-GGSGGAGGAAVGLFGNGGIGG-AGGGAE
TH_4332|M.thermoresistible__bu -----------PGSTIQMYFEASDGADGGRG-GFLFGNGGDGGNGG----
Mvan_3867|M.vanbaalenii_PYR-1 -NGGDGGTGFVSSAAGTNAASGGTGGAGGNG-GLLMGDGGKGGTGGRAIS
Mflv_5091|M.gilvum_PYR-GCK --TGGTGGIGGAGSTGGTGGTGGTGGTGGTG-GTG-GTGGTGGTGGTGGK
MSMEG_0868|M.smegmatis_MC2_155 TDTGGNGGRGGDGGTFVNAGANGNGGAGGAG-GVSEGEGGTGGHGGDGGR
MAB_4284c|M.abscessus_ATCC_199 --AGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGN
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 AG------------------------------------------------
Mb1871c|M.bovis_AF2122/97 GFAGGAGGTGGTGGLLYGNGGNGGNVPSGAAD--------------GGAG
Rv1840c|M.tuberculosis_H37Rv GFAGGAGGTGGTGGLLYGNGGNGGNVPSGAAD--------------GGAG
MUL_3056|M.ulcerans_Agy99 G-TGGPGGAGGTGGLLIGNGGNGGYDIQGGAF--------------GGDG
MMAR_2709|M.marinum_M GLNGGAGGVGGIGGKLYGDGGAGGIGGMGAADPS-------AAGGAGGAG
TH_4332|M.thermoresistible__bu --------------------------------------------NVGGKN
Mvan_3867|M.vanbaalenii_PYR-1 AEGPANGGNGGRGGNAGVLGGDAGGGGDGGRGYS------EKGPASGGAG
Mflv_5091|M.gilvum_PYR-GCK GGTGGTGGAGGTG----GDGGTGGTGGTGGTG---------GTGGTGGTG
MSMEG_0868|M.smegmatis_MC2_155 GGDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGGNG
MAB_4284c|M.abscessus_ATCC_199 AGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAG---------LAGNAGLAG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mb1871c|M.bovis_AF2122/97 GDAR---------LIGNGGDGGS------VGAAPTGIGNGGN--------
Rv1840c|M.tuberculosis_H37Rv GDAR---------LIGNGGDGGS------VGAAPTGIGNGGN--------
MUL_3056|M.ulcerans_Agy99 GNAR---------LIGNGGDGGV------EAGGPG--TTGGD--------
MMAR_2709|M.marinum_M GSAVG--------WFGDGGAGGAGGPVVPTAALGGLGGAGGA--------
TH_4332|M.thermoresistible__bu GAD---------PVTATVAADKS------------VAGGNG---------
Mvan_3867|M.vanbaalenii_PYR-1 GAG---------AAASTVGNGGSGGKGGSAQGAGSANGGAG---------
Mflv_5091|M.gilvum_PYR-GCK GAG-----------DGTGGTGGTGG----TGGQGGQGGQGG---------
MSMEG_0868|M.smegmatis_MC2_155 GAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIRATVI
MAB_4284c|M.abscessus_ATCC_199 NAG--------LAGNAAVAGNAAVAGNAAVAGNAAVGGVLN---------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mb1871c|M.bovis_AF2122/97 ------------GGNGGWLYGDGGSG-----------------------G
Rv1840c|M.tuberculosis_H37Rv ------------GGNGGWLYGDGGSG-----------------------G
MUL_3056|M.ulcerans_Agy99 ------------GGNGGWLLGNGGNG-----------------------A
MMAR_2709|M.marinum_M ------------GGNGGQLWGDGGAG-----------------------G
TH_4332|M.thermoresistible__bu ----------GNGGRGGLLFGLGGNG-----------------------G
Mvan_3867|M.vanbaalenii_PYR-1 ----------GSGGAGGFVSGDGGAG-----------------------G
Mflv_5091|M.gilvum_PYR-GCK --------TGGTGGQGG-LGGGGGTG-----------------------G
MSMEG_0868|M.smegmatis_MC2_155 GSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGTATDG
MAB_4284c|M.abscessus_ATCC_199 --------TGVSGAIGGSSHVGGAIN----------------------ES
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mb1871c|M.bovis_AF2122/97 STLQGFS-----------------------DG--------GTGGNAGMFG
Rv1840c|M.tuberculosis_H37Rv STLQGFS-----------------------DG--------GTGGNAGMFG
MUL_3056|M.ulcerans_Agy99 ADGGGAGSAAGAGGNAGLIGNGGHGGLEHIDGTGGAGSIAGAGGDAGLFG
MMAR_2709|M.marinum_M LGAFGQHG----------------------GGAG------GAGGNAGMVG
TH_4332|M.thermoresistible__bu NGGWSTTSYLDARGGNG--------------GNGGLG---GVLRPGGLLS
Mvan_3867|M.vanbaalenii_PYR-1 GGGTALSAAGTGSGGSG--------------GDGGNA---RGAGGGGRGG
Mflv_5091|M.gilvum_PYR-GCK QGGTGGTGGQGGTGGTGGTGGTG--------GTGGAG---GDGGLGGLGG
MSMEG_0868|M.smegmatis_MC2_155 HGGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNG---GDGIDGGLGG
MAB_4284c|M.abscessus_ATCC_199 LGGSGSVGGSTAVGGGA--------------HTGVGG---GVSTGVGVGS
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 -----------------------------------------PPAPAAPAA
Mb1871c|M.bovis_AF2122/97 DGGNGGFSFFDGNGGDGGTGGTLIGNGGDGGNSVQTDGFLRG----HGGD
Rv1840c|M.tuberculosis_H37Rv DGGNGGFSFFDGNGGDGGTGGTLIGNGGDGGNSVQTDGFLRG----HGGD
MUL_3056|M.ulcerans_Agy99 SGGNGGFNGYQGVGGAGGAGGKLFGDGGDGGDCAESNGGI-G----SGGR
MMAR_2709|M.marinum_M NGGDGGTALGLAHGGDGGTGGTLIGNGGAGGGATMS----------DAGD
TH_4332|M.thermoresistible__bu LLLPS-----GAASEPGGLFTGGNGGNG--GLAIANHWVGIT-----DGV
Mvan_3867|M.vanbaalenii_PYR-1 VGALG-----QSKDARG--FGGVGGAGG--RSGVTGTGGAGG-----AGG
Mflv_5091|M.gilvum_PYR-GCK FGGSGGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG----GSGS
MSMEG_0868|M.smegmatis_MC2_155 NGGDGVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWVQSGY
MAB_4284c|M.abscessus_ATCC_199 HVGGGISESLGGSGSVGGSTAVGGGAHTGVGGGVSTGVGVGS--HVGGGI
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 AAGAPVLASMGRGPSIGGLSVPPSWAPGGVAPAANATPAQLV------GA
Mb1871c|M.bovis_AF2122/97 GGNAVGLIGNGGAGGAGSAGTGVFAPGGGSG---------------GNGG
Rv1840c|M.tuberculosis_H37Rv GGNAVGLIGNGGAGGAGSAGTGVFAPGGGSG---------------GNGG
MUL_3056|M.ulcerans_Agy99 GGSAVGLIGNGGAGGVG--GVGRNANAGGSG---------------GSGG
MMAR_2709|M.marinum_M GGDAVGLIGSGGAGGIG--GAALAGGTGGTG---------------GDGG
TH_4332|M.thermoresistible__bu PGPDDDAVSSSAYGGHG--GHGAGPGSGGNG---------------GSAV
Mvan_3867|M.vanbaalenii_PYR-1 SGVSDTLDAAGGSGGDG--GDGSRGGIGGTG---------------GAAH
Mflv_5091|M.gilvum_PYR-GCK AGKAGATGAAGASGGKG--AQGATGAQGATG------AQGATG-ATGAAG
MSMEG_0868|M.smegmatis_MC2_155 GSTLGGNATGTATAGKG--GEASNGGVAGNGGNALVMAAGTTGVATGNTA
MAB_4284c|M.abscessus_ATCC_199 SESLGGSGSVGGSTAVG--GGAHTGVGGGVN----------TGVGVGSHV
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 GFTSAAPDTAPVTAVPGGVPSMATAGRGGYG--------------LGAPR
Mb1871c|M.bovis_AF2122/97 NGALLVGNGGAGGSGGPTQIPSV---------------------------
Rv1840c|M.tuberculosis_H37Rv NGALLVGNGGAGGSGGPTQIPSV---------------------------
MUL_3056|M.ulcerans_Agy99 NAAWLFGDGGAGGSGGSSD-------------------------------
MMAR_2709|M.marinum_M HGAKLLGNGGAGGAGGAAG-------------------------------
TH_4332|M.thermoresistible__bu ANS----------LGNAI--------------------------------
Mvan_3867|M.vanbaalenii_PYR-1 SKSGNAQGGFAGDGGTGS--------------------------------
Mflv_5091|M.gilvum_PYR-GCK KAGATGAAGAAGAAGSAG-----------TTGAQGSAGTNGA-NGANGSQ
MSMEG_0868|M.smegmatis_MC2_155 TGGDGGAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGK
MAB_4284c|M.abscessus_ATCC_199 GGGISESLGGSGSVGGST--------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 YGVKPTVMPKPAI-------------------------------------
Mb1871c|M.bovis_AF2122/97 ------------------------AVPVTGAGGTGGNGGTAGLIG-----
Rv1840c|M.tuberculosis_H37Rv ------------------------AVPVTGAGGTGGNGGTAGLIG-----
MUL_3056|M.ulcerans_Agy99 ----------------------------TAASGAGGNGGTAALIG-----
MMAR_2709|M.marinum_M --------------------------GGLGNGGNGGNGGEAALIG-----
TH_4332|M.thermoresistible__bu -------------------------AGNGGDAG------RFVLIG-----
Mvan_3867|M.vanbaalenii_PYR-1 -------------------------RGSGGDGGDGGIGTSTTGKG-----
Mflv_5091|M.gilvum_PYR-GCK GAAGKAGATGTTGATG--------AAGEDGDAGSGGSG-INGGAGGAGG-
MSMEG_0868|M.smegmatis_MC2_155 GADGWVQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGN
MAB_4284c|M.abscessus_ATCC_199 --------------------------AVGGGAHTSAINDALGGSGS----
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mb1871c|M.bovis_AF2122/97 -------------------NGGNGGAAGVSGDG-TPGTGGNGGYAQLIGD
Rv1840c|M.tuberculosis_H37Rv -------------------NGGNGGAAGVSGDG-TPGTGGNGGYAQLIGD
MUL_3056|M.ulcerans_Agy99 -------------------NGGAGGDAGVSFAG-MAGPGGNGGDARLIGD
MMAR_2709|M.marinum_M -------------------NGGAGGDAGTSGSSRNFGDGGNGGDAQLIGN
TH_4332|M.thermoresistible__bu ----------------PGGNGGNGGTGLXXXPRPRRRRNHRR------TR
Mvan_3867|M.vanbaalenii_PYR-1 ----------------RGGNGGNGGGGIRAAPVGKAAKARRAAAVAEATA
Mflv_5091|M.gilvum_PYR-GCK ----------------AGGEGGEGGDGGKGGAG--AEGGAGGGGGAGGSG
MSMEG_0868|M.smegmatis_MC2_155 TSVWKSGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTT
MAB_4284c|M.abscessus_ATCC_199 ----------------VGGSTAVGGGAHTSAINESMNSSINASHSSSMNE
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mb1871c|M.bovis_AF2122/97 GGDGGPGDSGGPGGSGGTGGTLAGQNGSPGG---------
Rv1840c|M.tuberculosis_H37Rv GGDGGPGDSGGPGGSGGTGGTLAGQNGSPGG---------
MUL_3056|M.ulcerans_Agy99 GGDGG---RGAPGGAGGMGGSLFGQDGSNGA---------
MMAR_2709|M.marinum_M GGNGGRGGVNGTGGTGGNGGTVAGANGTDGP---------
TH_4332|M.thermoresistible__bu RRPNGRRPRPPPGR--------------------------
Mvan_3867|M.vanbaalenii_PYR-1 PAPDGVVSLGPAYAQSRSATNALCCNEFSCAVTNSSEW--
Mflv_5091|M.gilvum_PYR-GCK AGGAG--GAGGSGGSGGSGGSGGSGGAAGDSDD-------
MSMEG_0868|M.smegmatis_MC2_155 AGGSGNGGNGGNGGNGGADGTPGTAGTTGANNP-------
MAB_4284c|M.abscessus_ATCC_199 SFGSSMGSHGAAGTGFEAQGHAQGHASETAHTTLPGAEHH
MLBr_01183|M.leprae_Br4923 ----------------------------------------
MAV_1346|M.avium_104 ----------------------------------------