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SFVVAAPDAVTAAVQDLASIGSAINVANAAAATPTTGALAAAADEVSAAVAALFDGHAQAYQLIGAQAAE FHERFVRAMAAGAASYATAEAANASPLQAALDAVNAPAQALLGRPLIGDGADGAPGQPGGAGGLLYGNGG SGGNGGIGQAGGAGGDAGLIGNGGSGGIGGPDSTGLPGGAGGAGGWLLGDGGNGGIGGAGTGIGGAGGSG GQGGAAAWLFGSGGTGGAGGFGNSGTGGPGGAGGTGGLLIGNGGNGGYDIQGGAFGGDGGNARLIGNGGD GGVEAGGPGTTGGDGGNGGWLLGNGGNGAADGGGAGSAAGAGGNAGLIGNGGHGGLEHIDGTGGAGSIAG AGGDAGLFGSGGNGGFNGYQGVGGAGGAGGKLFGDGGDGGDCAESNGGIGSGGRGGSAVGLIGNGGAGGV GGVGRNANAGGSGGSGGNAAWLFGDGGAGGSGGSSDTAASGAGGNGGTAALIGNGGAGGDAGVSFAGMAG PGGNGGDARLIGDGGDGGRGAPGGAGGMGGSLFGQDGSNGA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_3056 | - | - | 100% (532) | PE-PGRS family protein |
| M. ulcerans Agy99 | MUL_1145 | - | e-162 | 53.27% (642) | PE-PGRS family protein |
| M. ulcerans Agy99 | MUL_0212 | - | e-150 | 50.16% (644) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1360c | PE_PGRS24 | 1e-156 | 54.55% (583) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 2e-88 | 46.27% (456) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv1840c | PE_PGRS34 | 1e-168 | 59.71% (551) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01183 | - | 2e-12 | 37.50% (96) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 9e-42 | 32.51% (443) | hypothetical protein MAB_4284c |
| M. marinum M | MMAR_0299 | - | 1e-156 | 55.59% (572) | PE-PGRS family protein, PE_PGRS1 |
| M. avium 104 | MAV_1346 | - | 2e-21 | 34.19% (272) | PE family protein |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 2e-72 | 39.06% (530) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 2e-37 | 39.73% (297) | PUTATIVE - |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 2e-88 | 44.83% (522) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_3056|M.ulcerans_Agy99 --------------------------------------------------
Rv1840c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0299|M.marinum_M --------------------------------------------------
Mb1360c|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MUL_3056|M.ulcerans_Agy99 --------------------------------------------------
Rv1840c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0299|M.marinum_M --------------------------------------------------
Mb1360c|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MUL_3056|M.ulcerans_Agy99 --------------------------------------------------
Rv1840c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0299|M.marinum_M --------------------------------------------------
Mb1360c|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MUL_3056|M.ulcerans_Agy99 --------------------------------------------------
Rv1840c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0299|M.marinum_M --------------------------------------------------
Mb1360c|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MUL_3056|M.ulcerans_Agy99 --------------------------------------------------
Rv1840c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0299|M.marinum_M --------------------------------------------------
Mb1360c|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -------------------------MSIIDFILNLFRDPVEAASYVADPE
MUL_3056|M.ulcerans_Agy99 --------------------------------MS-FVVAAPDAVTAAVQD
Rv1840c|M.tuberculosis_H37Rv --------------------------------MS-FVVAAPEVVVAAASD
MMAR_0299|M.marinum_M --------------------------------MS-YVFATPELVAAAATD
Mb1360c|M.bovis_AF2122/97 --------------------------------MS-FVIAAPETLVRAASD
MLBr_01183|M.leprae_Br4923 --------------------------------MPLFLNAEPQALTAAANT
MAV_1346|M.avium_104 --------------------------------MS-FVTTRPEALLAVASM
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGG--NGGNGGNGL
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGG--NGGNGGNGL
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG---NGGNGGVGW
TH_3810|M.thermoresistible__bu -----------------------VDGDGGSGGRTGLFSKLSRGGDGGDGG
MAB_4284c|M.abscessus_ATCC_199 AALANAGLSAVSAAQVGAVMPVVAESVASNYGYQSQWVNTGNPIHDLSGN
MUL_3056|M.ulcerans_Agy99 LASIGSAINVANAAAATPTTGALAAAADEVSAAVAALFD---------GH
Rv1840c|M.tuberculosis_H37Rv LAGIGSAIGAANAAAAVPTMGVLAAGADEVSAAVADLFG---------AH
MMAR_0299|M.marinum_M LAGVQSVLSAANSAAAGPTMAVMAAGADEVSALIAGLFD---------AH
Mb1360c|M.bovis_AF2122/97 LANIGSTLGAANAAALGPTTELLAAGADEVSAAIASLFA---------AH
MLBr_01183|M.leprae_Br4923 LEGLSAATVASNAAAAQLTTEIAPPAADDVSILLAHFFS---------GH
MAV_1346|M.avium_104 LEGLGSSMDAQNAAAAAPTTSIAPAAADEVSALQAAQFS---------AY
Mflv_5091|M.gilvum_PYR-GCK GGGNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGA
Mvan_1264|M.vanbaalenii_PYR-1 GSGDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGA
MSMEG_0868|M.smegmatis_MC2_155 AGLDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGG
TH_3810|M.thermoresistible__bu LGGNGGHGGGTGIISLLSLAGNGGNGGNGYR----------------TTD
MAB_4284c|M.abscessus_ATCC_199 LQNYYAAQPDGPSILSPSLLSPRDNDFLSHNDTDFASHN-------PIAS
.
MUL_3056|M.ulcerans_Agy99 AQAYQLIGAQAAEFHERFVRAMAAGAASYATAEAANASPL-------QAA
Rv1840c|M.tuberculosis_H37Rv AQAYQALSAQAALFHEQFVHAMTAGAGAYAGAEAADA-----------AA
MMAR_0299|M.marinum_M AQAYQALSAQALVFHDQFVQMLNAGASSYAAAEAANASPLQVVQNLGQNV
Mb1360c|M.bovis_AF2122/97 GQAYQAVSAQMSAFHAQFVQTFTAGAGAYASAEAAAAAPL-------EGL
MLBr_01183|M.leprae_Br4923 GRQYQAHASQGATNHQDLIQSLLTSSSAYAGTETAN--------------
MAV_1346|M.avium_104 GTWYQQVSAQAKAIHQTLVQNLDTNADSYGATEAANR-------------
Mflv_5091|M.gilvum_PYR-GCK TGVTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG-------------
Mvan_1264|M.vanbaalenii_PYR-1 TGVTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG-------------
MSMEG_0868|M.smegmatis_MC2_155 TGGTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGG-FGYVLIAGP
TH_3810|M.thermoresistible__bu NNALDGGHGGNGGNVGFFSLFNLGGAGGWGGSGVDG--------------
MAB_4284c|M.abscessus_ATCC_199 GNQVMSPSGNVDSFNRGPLLDLSFGDLQFGNRDTTAIGDG------AVAV
. . .
MUL_3056|M.ulcerans_Agy99 LDAVNAPAQALLGRPLIGDGADGAP--GQPGGAGGLLYG-----------
Rv1840c|M.tuberculosis_H37Rv LDVLNGPFQALFGRPLIGDGANGAP--GQPGGPGGLLYG-----------
MMAR_0299|M.marinum_M LAAVNAPTQAVLGRPLIGDGANGSPNTGADGGAGGLLYG-----------
Mb1360c|M.bovis_AF2122/97 LNIVNTPTQLLLGRPLIGNGANGAPGTGQAGGAGGLLYG-----------
MLBr_01183|M.leprae_Br4923 --------------------------------HDSL--------------
MAV_1346|M.avium_104 ---VNTSAAALQGLAPNVIPNAAPAADPPPAGTTSLGTS-----------
Mflv_5091|M.gilvum_PYR-GCK --AVGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG-------------
Mvan_1264|M.vanbaalenii_PYR-1 --AVGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG-------------
MSMEG_0868|M.smegmatis_MC2_155 NVTVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTV
TH_3810|M.thermoresistible__bu ---VDVVGGNPDGGTPGAHG--ESHTPGVYTDR-----------------
MAB_4284c|M.abscessus_ATCC_199 GGSNSGPIASGQGSTAVNGDVRDSNIINADHGSNVGVD------------
MUL_3056|M.ulcerans_Agy99 ---------------------------------------------NGGSG
Rv1840c|M.tuberculosis_H37Rv ---------------------------------------------NGGNG
MMAR_0299|M.marinum_M ---------------------------------------------NGGNG
Mb1360c|M.bovis_AF2122/97 ---------------------------------------------NGGAG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 ---------------------------------------------IGWAQ
Mflv_5091|M.gilvum_PYR-GCK ---AVGAAGAAG------TVGTAGATGGTG---------------TGANG
Mvan_1264|M.vanbaalenii_PYR-1 ---AIGTAGVAG------AAGTAGATGGTG---------------VGGNG
MSMEG_0868|M.smegmatis_MC2_155 DGHAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDG
TH_3810|M.thermoresistible__bu ---------------------------------------------QGEDG
MAB_4284c|M.abscessus_ATCC_199 ---------------------------------------------QSQTR
MUL_3056|M.ulcerans_Agy99 GNGGIGQAGGAGGDA-----------------------------------
Rv1840c|M.tuberculosis_H37Rv GNGGIGQPGGAGGDA-----------------------------------
MMAR_0299|M.marinum_M GSGGLAQAGGNGGAA-----------------------------------
Mb1360c|M.bovis_AF2122/97 GSGAPGQAGGPGGAA-----------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 NVGAAASDFITLGEG-----------------------------------
Mflv_5091|M.gilvum_PYR-GCK GAGGVGGVGGTGAAG--------------AAGGAGGLGETGTTGGAGGVG
Mvan_1264|M.vanbaalenii_PYR-1 GAGQAGGIGGTGAAG--------------AAGQAGTAGETGVTGGVGGIG
MSMEG_0868|M.smegmatis_MC2_155 GHSTGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMG
TH_3810|M.thermoresistible__bu EDGTGTGIGGRGGNG-----------------------------------
MAB_4284c|M.abscessus_ATCC_199 VGGDYTNVSGHGSADIDKS-------------------------------
MUL_3056|M.ulcerans_Agy99 -----------GLIGNGGSGGIGGPDS-TGLPG-----------------
Rv1840c|M.tuberculosis_H37Rv -----------GLIGNGGNGGIGGPGA-TGLAG-----------------
MMAR_0299|M.marinum_M -----------GLIGNGGSGGAGGADF-AGTSG-----------------
Mb1360c|M.bovis_AF2122/97 -----------GLFGNGGAGGAGGDGPGNGAAG-----------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 -----------QFAPVPGAAGIPNFNPGLTAAT-----------------
Mflv_5091|M.gilvum_PYR-GCK GQ--GTAGGTGGVGGIGGAGSTGAVGGVGGKG----IQGGQG--------
Mvan_1264|M.vanbaalenii_PYR-1 GQ--GTEGGTGGVGGVGGVGATGGAGGVGGKG----IQGGQG--------
MSMEG_0868|M.smegmatis_MC2_155 EIYSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKAS
TH_3810|M.thermoresistible__bu -------------------GSSSGTHPMAEDG------------------
MAB_4284c|M.abscessus_ATCC_199 ---------VTVVDDHSQRNTTNINDSFNTDRSTN---------------
MUL_3056|M.ulcerans_Agy99 -------GAGGAGGWLLGDGGNGGIGGAGTG-----------------IG
Rv1840c|M.tuberculosis_H37Rv -------GAGGVGGLLFGDGGNGGAGGLGTGP----------------VG
MMAR_0299|M.marinum_M -------GMGGTGGWLWGNGGAGGGGGVGTT-------------------
Mb1360c|M.bovis_AF2122/97 -------GAGGAGGLLFGSGGAGGPGGVGNT-------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 -------TAGPP--------------------------------------
Mflv_5091|M.gilvum_PYR-GCK -----LQGGKGGDGGAGGKGGDADSMGS------------------AGAT
Mvan_1264|M.vanbaalenii_PYR-1 -----LQGGQGGDGGTGGTGGDATSMGE------------------AGAT
MSMEG_0868|M.smegmatis_MC2_155 GTAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASAN
TH_3810|M.thermoresistible__bu ------EHVKALDGRPGLDGG----------------------------N
MAB_4284c|M.abscessus_ATCC_199 ------IGSGNTTNTEIGSHNQANIGTSTSAG----------------GS
MUL_3056|M.ulcerans_Agy99 GAGGSGGQGGAAAWLFG---------------------------------
Rv1840c|M.tuberculosis_H37Rv ATGGIGGPGGAAVGLFG---------------------------------
MMAR_0299|M.marinum_M TTGGTGGAGGNAMGLFG---------------------------------
Mb1360c|M.bovis_AF2122/97 GTGGLGGDGG-AAGLFG---------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 -APAAPAAAAGAPVLAS---------------------------------
Mflv_5091|M.gilvum_PYR-GCK GGKGGNGGNGGRGGLFG---------------KGGNAGNGAD--------
Mvan_1264|M.vanbaalenii_PYR-1 GGKGGNGGNGGRGSLFG---------------RGGNAGNGGN--------
MSMEG_0868|M.smegmatis_MC2_155 GAVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDP
TH_3810|M.thermoresistible__bu GSHGGNGGHGGRGGFLG---------------------------------
MAB_4284c|M.abscessus_ATCC_199 AAVGGNAGLAGNAGLAG---------------------------------
MUL_3056|M.ulcerans_Agy99 -------------SGGTGGAGGFGNSG--TGGPGGAGG------------
Rv1840c|M.tuberculosis_H37Rv -------------HGGAGGAGGLGKAGF-AGGAGGTGG------------
MMAR_0299|M.marinum_M -------------NGGIGGAGGVGQNTTGTGGNGGAGG------------
Mb1360c|M.bovis_AF2122/97 -------------AGGIGGAGGPGFNGG-AGGAGGRSG------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 -------------MGRGPSIGGLSVPPSWAPGGVAPAA------------
Mflv_5091|M.gilvum_PYR-GCK --------------GGTGGAGGAGGTGG-TGGAGGTGG------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------GGTGGNGGNGGTGG-TGGNGGTGG------------
MSMEG_0868|M.smegmatis_MC2_155 NGPAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHS
TH_3810|M.thermoresistible__bu -------------IGGSGGWGGHGGNGGDTDADGGNGG------------
MAB_4284c|M.abscessus_ATCC_199 -------------NAGLAGNAGLAGNAGLAGNAGLAGN------------
MUL_3056|M.ulcerans_Agy99 ---------------------------------TGGLL--IGNGGNGGYD
Rv1840c|M.tuberculosis_H37Rv ---------------------------------TGGLL--YGNGGNGGNV
MMAR_0299|M.marinum_M ---------------------------------NAALLGFAGAGGVGGLG
Mb1360c|M.bovis_AF2122/97 ---------------------------------LFEVLAAGGAGGTGGLS
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 ---------------------------------NATPAQLVGAGFTSAAP
Mflv_5091|M.gilvum_PYR-GCK -----TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTG
Mvan_1264|M.vanbaalenii_PYR-1 -----TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTG
MSMEG_0868|M.smegmatis_MC2_155 TGQTDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGDG
TH_3810|M.thermoresistible__bu ------------------------------------------DGGNGGSA
MAB_4284c|M.abscessus_ATCC_199 ----------------------------------AGLAGNAGLAGNAGLA
MUL_3056|M.ulcerans_Agy99 IQG--GAFGGDGGNA----------------------------RLIGNGG
Rv1840c|M.tuberculosis_H37Rv PSG--AADGGAGGDA----------------------------RLIGNGG
MMAR_0299|M.marinum_M GAT--GGDGGQGGNA----------------------------ALFGNGG
Mb1360c|M.bovis_AF2122/97 VNGGTGGTGGTGGGG----------------------------GLFSNGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 DTAPVTAVPGGVPSM----------------------------ATAGRGG
Mflv_5091|M.gilvum_PYR-GCK GKGGTGGTGGAGGTG----GDGGTGGTGGTGGTG---------GTGGTGG
Mvan_1264|M.vanbaalenii_PYR-1 GKGGTGGTGGDGGTG----GTGGTGGTGGTGGTG---------GTGGTGG
MSMEG_0868|M.smegmatis_MC2_155 GRGGDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGG
TH_3810|M.thermoresistible__bu GRGGTGGLRGVFGIN---------------------------------GG
MAB_4284c|M.abscessus_ATCC_199 GNAGLAGNAGLAGNAG----------------------------LAGNAG
MUL_3056|M.ulcerans_Agy99 DGGVEA-----GGPG--TTGGDGGNGG---WLLGNGGNGAADGG------
Rv1840c|M.tuberculosis_H37Rv DGGSVG-----AAPTGIGNGGNGGNGG---WLYGDGGSGGSTLQ------
MMAR_0299|M.marinum_M DGGAGG-----AGAN--LDGGNGGLGGNA-GLFGDGGHGGAGGV------
Mb1360c|M.bovis_AF2122/97 AGGAGG-----FGVSG-SAGGNGGTGGDGGIFTGNGGTGGAGGTG-----
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 YGLGAP-----RYGVKPTVMPKPAI-------------------------
Mflv_5091|M.gilvum_PYR-GCK TGGAG-----------DGTGGTGGTGG----TGGQGGQGGQGG-------
Mvan_1264|M.vanbaalenii_PYR-1 TGGAG-----------DGLGGTGGTGG----TGGFGGQGGQGG-------
MSMEG_0868|M.smegmatis_MC2_155 NGGAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIRAT
TH_3810|M.thermoresistible__bu NGRAG-----------------------------LGGRGXXXX-------
MAB_4284c|M.abscessus_ATCC_199 LAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAG-----
MUL_3056|M.ulcerans_Agy99 ------GAGSAAGAGGNAGLIGNG-GHGGLEHIDGTGG------------
Rv1840c|M.tuberculosis_H37Rv ------GFS------------------------DG---------------
MMAR_0299|M.marinum_M ------SFDPAGGDGGNGGQGGNA-TLFGYGGHGGAGGSSL--------N
Mb1360c|M.bovis_AF2122/97 -----TGNQLVGGEGGAGGAGGNAGILFGAGGIGGTGGTGLGAPDPGGTG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----------TGGTGGQGG-LGGGGGTG----------------------
Mvan_1264|M.vanbaalenii_PYR-1 ----------TGGTGGQGG-LGGVGGTG----------------------
MSMEG_0868|M.smegmatis_MC2_155 VIGSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGTAT
TH_3810|M.thermoresistible__bu ----------GGGVG-----------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----------NAGLAGNAAVAGNAAVAGNAAVAGNAAVGG---------V
MUL_3056|M.ulcerans_Agy99 -AGSIAGAGGDAGLFG---SGGNGGFNG------YQGVGGAGGAGG--KL
Rv1840c|M.tuberculosis_H37Rv ------GTGGNAGMFG---DGGNGGFSF------FDGNGGDGGTGG--TL
MMAR_0299|M.marinum_M LAGGDGGDGGQGGFFGGGGAGGDGGAGY------VLANAGAAGNGGDAGF
Mb1360c|M.bovis_AF2122/97 GKGGVGGIGGAGALFGPGGAGGTGGFGASSADQMAGGIGGSGGSGGAAKL
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK -GQGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGF
Mvan_1264|M.vanbaalenii_PYR-1 -GTGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGF
MSMEG_0868|M.smegmatis_MC2_155 DGHGGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGLGGN
TH_3810|M.thermoresistible__bu ----------------------------------AAVRSGNGVFSGGGGT
MAB_4284c|M.abscessus_ATCC_199 LNTGVSGAIGGSSHVGGAINESLGGSGSVGGSTAVGGGAHTGVGGGVSTG
MUL_3056|M.ulcerans_Agy99 FGDGGDGGDCAESNGGI-GSGGR----GGSAVGLIGNGGAGGVG--GVGR
Rv1840c|M.tuberculosis_H37Rv IGNGGDGGNSVQTDGFLRGHGGD----GGNAVGLIGNGGAGGAGSAGTGV
MMAR_0299|M.marinum_M FGNGGAGG-SGQFGVGASSAGGI----GGNGGRVIGDGGDGGVG--GWGV
Mb1360c|M.bovis_AF2122/97 IGDGGAGGTGGDSVRGAAGSGGT----GGTG-GLIGDGGAGGAG--GTGI
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GGSGGTGGQGGLGGPGGSTGGAG----GAGG--QAGTAGKGGLFG----G
Mvan_1264|M.vanbaalenii_PYR-1 GGVGGTGGQGGQGGPGGSTGGAG----GAGG--QAGVAGKGGLFG----G
MSMEG_0868|M.smegmatis_MC2_155 GGDGVVNTTANAANPGSATGTAT----GGDGGKATGTASQGGNGGPSWVQ
TH_3810|M.thermoresistible__bu PSAGFGVPTTIQFPAGSCTSRAV----SREGIMPSSRAAS----------
MAB_4284c|M.abscessus_ATCC_199 VGVGSHVGGGISESLGGSGSVGGSTAVGGGAHTGVGGGVSTGVGVGSHVG
MUL_3056|M.ulcerans_Agy99 NA-NAGGSGGSGGNAAWLFGDGGAGGSGGSSD------------------
Rv1840c|M.tuberculosis_H37Rv FA-PGGGSGGNGGNGALLVGNGGAGGSGGPTQIPSVAVP-----------
MMAR_0299|M.marinum_M LA-AAG---GKGGDAIGLFGQGGAGGTGGAAVG-----------------
Mb1360c|M.bovis_AF2122/97 EFGSVGGAGGAGGNAAGLSGAGGAGGAGGFGETAGDGGAGGNAGLLNGDG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK SGSAGKAGATGAAGASGGKGAQGATGAQGATG------AQGATG-ATGAA
Mvan_1264|M.vanbaalenii_PYR-1 SGSAGTAGVTGASGASGGKGAQGATGAQGATG------AQGATG-ATGAS
MSMEG_0868|M.smegmatis_MC2_155 SGYGSTLGGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNT
TH_3810|M.thermoresistible__bu ----ARAGAACASSTSRSRRSFCCSRA-----------------------
MAB_4284c|M.abscessus_ATCC_199 GGISESLGGSGSVGGSTAVGGGAHTGVGGGVNTGVGVGSHVGGGISESLG
MUL_3056|M.ulcerans_Agy99 ----------TAASG-----------------------------------
Rv1840c|M.tuberculosis_H37Rv ---------VTGAGG-----------------------------------
MMAR_0299|M.marinum_M ---------AGNHGG-----------------------------------
Mb1360c|M.bovis_AF2122/97 GAGGAGGLGIAGDGG-----------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GKAGATGAAGAAGAAGSAG-----------TTGAQGSAGTNGA-NGANGS
Mvan_1264|M.vanbaalenii_PYR-1 GAQGSAGSAGSAGVAGSAG-----------TTGAQGSAGTNGA-NGANGS
MSMEG_0868|M.smegmatis_MC2_155 ATGGDGGAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GSGSVGGSTAVGGGAHTSAIN-----------------------------
MUL_3056|M.ulcerans_Agy99 -----------------------------------------AGGNGGTAA
Rv1840c|M.tuberculosis_H37Rv -----------------------------------------TGGNGGTAG
MMAR_0299|M.marinum_M -----------------------------------------NGGDGGTGA
Mb1360c|M.bovis_AF2122/97 -----------------------------------------NGGKGGKAG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK QGAAGKAGATGTTGATG--------AAGEDGDAGSGGSG-INGGAGGAGG
Mvan_1264|M.vanbaalenii_PYR-1 QGAAGKAGATGTTGATG--------AAGDAGDPGSEAVD-INGGAGGAGG
MSMEG_0868|M.smegmatis_MC2_155 KGADGWVQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ---------------------------------------DALGGSGSVGG
MUL_3056|M.ulcerans_Agy99 LIGNGGAGGDAGVSFAGMAGPGGNGGDARLIGDGGDGG---RGAPGGAGG
Rv1840c|M.tuberculosis_H37Rv LIGNGGNGGAAGVSGDGTPGTGGNGGYAQLIGDGGDGGPGDSGGPGGSGG
MMAR_0299|M.marinum_M LIGNGGDGGAAGTS-IGQSASGGNGGNARFLGNGGDGGPGIFGGTGGTGG
Mb1360c|M.bovis_AF2122/97 MVGNGGDGGAGGASVVANGGVGGSGGNATLIGNGGNGGNGGVGSAPGKGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK -----------AGGEGGEGGDGGKGGAGAEGGAGGGGGAGGSGAGGAG--
Mvan_1264|M.vanbaalenii_PYR-1 -----------AGGEGGEGGAGGAGGDGSEGGAGGSGGAGGSGTGGAG--
MSMEG_0868|M.smegmatis_MC2_155 NTSVWKSGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 STAVGGGAHTSAINESMNSSINASHSSSMNESFGSSMGSHGAAGTGFEAQ
MUL_3056|M.ulcerans_Agy99 MGGS--LFGQDGSNGA------------------
Rv1840c|M.tuberculosis_H37Rv TGGT--LAGQNGSPGG------------------
MMAR_0299|M.marinum_M QGGT--LAGVPGAAGPS-----------------
Mb1360c|M.bovis_AF2122/97 AGGTAGLLGLNGSPGLS-----------------
MLBr_01183|M.leprae_Br4923 ----------------------------------
MAV_1346|M.avium_104 ----------------------------------
Mflv_5091|M.gilvum_PYR-GCK -----GAGGSGGSGGSGGSGGSGGAAGDSDD---
Mvan_1264|M.vanbaalenii_PYR-1 -----GAGGSGGSGGSGGAGGSGGAAGDSD----
MSMEG_0868|M.smegmatis_MC2_155 TAGGSGNGGNGGNGGNGGADGTPGTAGTTGANNP
TH_3810|M.thermoresistible__bu ----------------------------------
MAB_4284c|M.abscessus_ATCC_199 GHAQGHASETAHTTLPGAEHH-------------