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M. thermoresistible (build 8) TH_2477 (-)

annotation: acyltransferase, ws/dgat/mgat subfamily protein
coordinates: 907255 - 908670
length: 472

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2477--100% (472)acyltransferase, ws/dgat/mgat subfamily protein
M. thermoresistible (build 8)TH_3760-3e-6532.98% (470) PUTATIVE Diacylglycerol O-acyltransferase
M. thermoresistible (build 8)TH_2030-2e-5932.71% (480) CONSERVED HYPOTHETICAL PROTEIN

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1791-1e-13957.28% (412) hypothetical protein Mb1791
M. gilvum PYR-GCKMflv_5212-1e-15157.52% (459) hypothetical protein Mflv_5212
M. tuberculosis H37RvRv1760-1e-15757.61% (460) hypothetical protein Rv1760
M. leprae Br4923MLBr_01244-1e-2224.42% (389) hypothetical protein MLBr_01244
M. abscessus ATCC 19977MAB_1917-1e-18065.14% (459) hypothetical protein MAB_1917
M. marinum MMMAR_3298-0.072.14% (463) hypothetical protein MMAR_3298
M. avium 104MAV_2240-0.069.87% (458) acyltransferase, ws/dgat/mgat subfamily protein
M. smegmatis MC2 155MSMEG_4297-0.079.57% (460) acyltransferase, ws/dgat/mgat subfamily protein
M. ulcerans Agy99MUL_1818-4e-8741.91% (470) hypothetical protein MUL_1818
M. vanbaalenii PYR-1Mvan_3601-0.078.96% (461) hypothetical protein Mvan_3601

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_4297|M.smegmatis_MC2_155      ----------------------------------MQRLSGLDASFLYLET
Mvan_3601|M.vanbaalenii_PYR-1       -------------------MDLLTPAPPRHTIGGMQRLSGLDASFLYLES
TH_2477|M.thermoresistible__bu      -------------------------VPPPYDRG-MQRLSGLDASFLYLET
MMAR_3298|M.marinum_M               ----------------------------------MQRLSGLDASFLYLET
MAV_2240|M.avium_104                -------------------------------MLRMQRLSGLDASFLYLET
MAB_1917|M.abscessus_ATCC_1997      ----------------------------------MQRLSGLDASFLYLET
Mb1791|M.bovis_AF2122/97            MPRGCAGARFACNACLNFLAGLGISEPISPGWAAMERLSGLDAFFLYMET
Rv1760|M.tuberculosis_H37Rv         MPRGCAGARFACNACLNFLAGLGISEPISPGWAAMERLSGLDAFFLYMET
Mflv_5212|M.gilvum_PYR-GCK          ----------------------------------MERLSGLDAGMLYSES
MUL_1818|M.ulcerans_Agy99           ----------------------------------MRRLSSVDAAFWSAET
MLBr_01244|M.leprae_Br4923          ------------------------MADSVEGIGPFDELGALDYLLHRGEA
                                                                      : .*..:*  :   *:

MSMEG_4297|M.smegmatis_MC2_155      -AAQPMHVCSVLELDTSTMPGGYTFDRLRDALSLRIKAMPEFREKLADSR
Mvan_3601|M.vanbaalenii_PYR-1       -AAQPLHVCSILELDTSTMPGGYTFDRLRDGLALRIKAMPEFREKIADSR
TH_2477|M.thermoresistible__bu      -PDQPLHVCSILELDTSTIPGGYDFHQLREALLLRIKAMPEFREKLADNR
MMAR_3298|M.marinum_M               -SNQPMHVCSIMELDTSTMPGGYTFDRLQDALALRIKAMPEFREKLANSA
MAV_2240|M.avium_104                -SSQPMHVCSIIELDTSTVPGGYTFERLRDALVRRIRAVPPFREKLADSP
MAB_1917|M.abscessus_ATCC_1997      -PTQPMHVCGVLELDTTTIPGGYSFEKLRTKLAERVEGIPSFREKLADSR
Mb1791|M.bovis_AF2122/97            -PSQPLNVCCVLELDTSTMPGGYTYGRFHAALEKYVKAAPEFRMKLADTE
Rv1760|M.tuberculosis_H37Rv         -PSQPLNVCCVLELDTSTMPGGYTYGRFHAALEKYVKAAPEFRMKLADTE
Mflv_5212|M.gilvum_PYR-GCK          -PTVPLHVCSVTELDTSTVPGGYTFAKFRDHLASRVPAIPEFRTKLADND
MUL_1818|M.ulcerans_Agy99           -AGWHMHVGALAICDPTDAP-DYSFQRLRELLIERLPEIPQLRWRVTGAP
MLBr_01244|M.leprae_Br4923          NPRTRAGIMAVELLDT-----TPDWNRFRSRIEDVSQRVLRLRQKVVVPT
                                     .     :  :   *.        : :::  :         :* ::.   

MSMEG_4297|M.smegmatis_MC2_155      FNLDHPVWVEDNDFDVDRHLHRIGLPGPGGRAELAEICGHIASLPLDRSR
Mvan_3601|M.vanbaalenii_PYR-1       FNLDHPVWVEDNDFDVDRHLHRIGLPSPGGRVELAEICGHIASLPLDRTR
TH_2477|M.thermoresistible__bu      FNLDHPVWVEDADFDVDRHLHRIGLPAPGGPAELAEICGHLAALPLDRSR
MMAR_3298|M.marinum_M               LNLDHPVWVDDEDFQLHRHLHRIGLPPPGGRAELSQICGHIASLPLDRSR
MAV_2240|M.avium_104                LNLDHPVWVDDEDFDVDRHLHRIAVPAPGGRAELSQICGHIAQTPLDRRR
MAB_1917|M.abscessus_ATCC_1997      LNLDHPVWVDDDDFDIDRHLHHVGLPAPGGKAEIADMCGHIASLPLDRAR
Mb1791|M.bovis_AF2122/97            LNLDHPVWVDDDNFQIRHHLRRVAMPAPGGRRELAEICGYIAGLPLDRDR
Rv1760|M.tuberculosis_H37Rv         LNLDHPVWVDDDNFQIRHHLRRVAMPAPGGRRELAEICGYIAGLPLDRDR
Mflv_5212|M.gilvum_PYR-GCK          LNFDHPVWVEDDDFDLTRHLNRVALPEPGGRDELAELCGRLIGMPLERSK
MUL_1818|M.ulcerans_Agy99           LGLDRPWFVEDQDLDVDFHVRRIGVPAPGGRRELEELVGRLMSYKLDRSR
MLBr_01244|M.leprae_Br4923          LPTAAPRWVVDPDFELDFHVRRVRVPDPGTLREVFDLAEVIQQSPMDVSR
                                    :    * :* * ::::  *:.:: :* **   *: ::   :    ::  :

MSMEG_4297|M.smegmatis_MC2_155      PLWEMWVIENVAGTDAHAGGRLALMTKVHHASVDGVTGANLLSQLCTTEP
Mvan_3601|M.vanbaalenii_PYR-1       PLWEMWVIENVAGTDAHAGGRIAVMTKVHHAAVDGVTGANLMSKLCTTEP
TH_2477|M.thermoresistible__bu      PLWEMWVIENIDGTDPRSGGPLVVLTKVHHAAVDGVTGANLLSQVCTTEA
MMAR_3298|M.marinum_M               PLWEMWVIEGVAGTDCHHDGRLAVLTKVHHAAVDGVTGANLMSQLCTTEA
MAV_2240|M.avium_104                PLWEMWVIEGVAGTDCHRDGRLAVMTKVHHAGVDGVTGANLMSQLCATEP
MAB_1917|M.abscessus_ATCC_1997      PLWEMWVIETGDTN------RLVVMTKMHHASVDGVTGANLMSALCGLEP
Mb1791|M.bovis_AF2122/97            PLWEMWVIEGGARSD-----TVAVMLKVHHAVVDGVAGANLLSHLCSLQP
Rv1760|M.tuberculosis_H37Rv         PLWEMWVIEGGARSD-----TVAVMLKVHHAVVDGVAGANLLSHLCSLQP
Mflv_5212|M.gilvum_PYR-GCK          PLWEMWVIEGVGGSAAREDGRLALLLKVHHAAVDGVSAADLLAKLLDTEP
MUL_1818|M.ulcerans_Agy99           PLWELWVIEGVEGG------RIATLTKMHHAIVDGVSGAGLGEILLDVTP
MLBr_01244|M.leprae_Br4923          PLWTATLVEGLAAG------RAAMLLQISHAITDGVGSVEMFAEMYDLER
                                    ***   ::*             . : :: ** .*** .. :   :     

MSMEG_4297|M.smegmatis_MC2_155      DAPPP--DPVDGPGGGTGLEIAVNGAVRFATR------------PLRLVN
Mvan_3601|M.vanbaalenii_PYR-1       DAPPP--DPVAGPGGGTDLEIAVSGAVRFATR------------PLKLVN
TH_2477|M.thermoresistible__bu      DTPPP--EPVQGAGTASDLEIALSGAVRFATR------------PLKLLN
MMAR_3298|M.marinum_M               DAPAP--DPVDGVGGATDWQIAAGGLLRFATR------------PLQLAN
MAV_2240|M.avium_104                DAAPP--EPAAGVGGGAGWRIAAGGLVRFAAR------------PLRLAS
MAB_1917|M.abscessus_ATCC_1997      DAEAP--EPAPGVGGANSLEIAVTGALKWASR------------PLKFAK
Mb1791|M.bovis_AF2122/97            DAPAP--QPVRGTGGGNVLQIAASGLVGFASR------------PVRLAT
Rv1760|M.tuberculosis_H37Rv         DAPAP--QPVRGTGGGNVLQIAASGLEGFASR------------PVRLAT
Mflv_5212|M.gilvum_PYR-GCK          DAPPP--DPVDAPTGASTWEIAADGLWRVATR------------PWQLTR
MUL_1818|M.ulcerans_Agy99           EPRPPQ-EETVGFVGFQIPRLERRAVGALINVGIM--------TPFRIAR
MLBr_01244|M.leprae_Br4923          DPPSRPRSPQPIPQDLSRNDLMLQGINHLPVALAGGVVGGLSGVASVAGR
                                    :. .   .            :   .                   .     

MSMEG_4297|M.smegmatis_MC2_155      VVPSTLNTVVDTVRRARNGRTMAAPFAAPRTAFNANITGHRNIAFAQLDL
Mvan_3601|M.vanbaalenii_PYR-1       VVPNTVSTVIDTVKRARNGLTMAPPFAAPKTAFNANVTGHRNVAFAQLDL
TH_2477|M.thermoresistible__bu      VLPTTANSVLDTVRRARAGRTMARPFAAPSTPFNANVTGRRNVAFTQLDL
MMAR_3298|M.marinum_M               VVPETVSSVVSTLLRAREGLTMARPFTAPRTVFNARVSGRRAVAYAELDL
MAV_2240|M.avium_104                VVPDTAASVLATVRRALDGAAMARPFAAPTTVFNARISNRRCIAYAELNL
MAB_1917|M.abscessus_ATCC_1997      LLPATIGVIPAWLERSKRGEAMSAPFSAPRTSFNSTITSRRNVGYAQLDL
Mb1791|M.bovis_AF2122/97            VVPATVLTLVRTLLRAREGRTMAAPFSAPPTPFNGPLGRLRNIAYTQLDM
Rv1760|M.tuberculosis_H37Rv         VVPATVLTLVRTLLRAREGRTMAAPFSAPPTPFNGPLGRLRNIAYTQLDM
Mflv_5212|M.gilvum_PYR-GCK          VVPVATSLVTNTVSRALSGTAMALPFSAPSTPFNAPLTSDRNIAFAQLDL
MUL_1818|M.ulcerans_Agy99           LVEQTVRQQIAALGVSARP---PRYFDAPKTRFNAHVSPHRRVSGCRIEL
MLBr_01244|M.leprae_Br4923          AILRPASTVSGVVGYVRSGIRVLSQAAEPSPLLRQRSLATR-TEAIEIQL
                                     :  .       :               * . :.      *     .:::

MSMEG_4297|M.smegmatis_MC2_155      EDIKTVKNHFDVKVNDVVMALVSGVLRTFLSHRDELPDNSLVAMVPVSVH
Mvan_3601|M.vanbaalenii_PYR-1       EDIKTVKNHFGVKVNDVVMALVSGVLRTFLLERGELPESSLVAMVPVSVH
TH_2477|M.thermoresistible__bu      EDVKRIKDHFGVKVNDVVMALTSGALRSYLLERDQLPDSPLIAMVPVSVH
MMAR_3298|M.marinum_M               EDIKAVKNHFGVKVNDVVMGLVSGVLRNYLADRDALPTSSLVASVPVSVH
MAV_2240|M.avium_104                DDVKAVKNHFGVKVNDVVMALVSGVLRQYLAERNALPDSSLVASVPISVH
MAB_1917|M.abscessus_ATCC_1997      EDVRTVKNHFGVKVNDVVMAICAGALRKYLDDRGELPDNSLVAMVPVSVH
Mb1791|M.bovis_AF2122/97            RDVKRVKDRFGVTINDVVVALCAGALRRFLLEHGVLPEAPLVATVPVSVH
Rv1760|M.tuberculosis_H37Rv         RDVKRVKDRFGVTINDVVVALCAGALRRFLLEHGVLPEAPLVATVPVSVH
Mflv_5212|M.gilvum_PYR-GCK          DDVKKVKNQAEVKVNDVVMALCAGALRGYLDERGALPDKPLIAVVPSSVH
MUL_1818|M.ulcerans_Agy99           ARAKAVKDAFGVKLNDVVLATVAGAAREYLKKRDELPAKPLIAQIPVSTR
MLBr_01244|M.leprae_Br4923          SDLHKAAKAGDGSINDAYLAGLVGALRRYHEALG-VSISTLPMAVPVNVR
                                       :   .    .:**. :.   *. * :    . :.  .*   :* ..:

MSMEG_4297|M.smegmatis_MC2_155      DRSDRPGR-NQVSGMFSPLQTHIADPAERLRAIAEANAVAKQHSSAIGAT
Mvan_3601|M.vanbaalenii_PYR-1       DKSDRPGR-NQVSGMFSRLETNIEDPATRLKAIAEANSVAKQHSSAIAAT
TH_2477|M.thermoresistible__bu      DKTDRPGR-NHVSGMFSRLETTIEDPAERLRAIANANSVAKQHSSAIAAS
MMAR_3298|M.marinum_M               GKSDRPGR-NQVSAMFSSLHTEIADPAERLNAIAHGNTVAKGHSSAIGAT
MAV_2240|M.avium_104                GKSDRPGR-NQVSAMFASLHTEIADPVQRLKAIAHANSLAKEHSSAIGAS
MAB_1917|M.abscessus_ATCC_1997      EKSDRPGR-NQVSGMFSRLETNVDDPVERLNAIAAANNIAKDHTAVLGAT
Mb1791|M.bovis_AF2122/97            DKSDRPGR-NQATWMFCRVPSQISDPAQRIRTIAAGNTVAKDHAAAIGPT
Rv1760|M.tuberculosis_H37Rv         DKSDRPGR-NQATWMFCRVPSQISDPAQRIRTIAAGNTVAKDHAAAIGPT
Mflv_5212|M.gilvum_PYR-GCK          GQTDRPGR-NQLSGMFCNLHTDIEDPLDRLYAIGASNVRAKEHSGSLGPS
MUL_1818|M.ulcerans_Agy99           TDQTKEDVGNQISSMTASLATHINDPAERLKAIHESTQNAKEMAKALSAH
MLBr_01244|M.leprae_Br4923          TEADVVGS-NRFVGVTLAAPLGTNDPAARMQKIRSQMTQRRDEPAMNIIG
                                          .  *:   :         **  *:  *       :  .      

MSMEG_4297|M.smegmatis_MC2_155      LLQDWTQFAAPAVFGTAMRVYAASRLSGAKP-VHNLVVSNVPGPQVPLYF
Mvan_3601|M.vanbaalenii_PYR-1       LLQDWTQFAAPAVFGAAMRVYASSRLSGARP-VHNLVISNVPGPQGPLYM
TH_2477|M.thermoresistible__bu      LLQDWTQFAAPAVFGVAMRVYAASRLGEAKP-VHNLVVSNVPGPQVPLYF
MMAR_3298|M.marinum_M               LLQDWSQFAAPAVFGAAMRVYASSRLTESLP-VHNLVVSNVPGPQLPLYM
MAV_2240|M.avium_104                LLQDWTQFAAPAVFGIAMRLYARTRFTDSMP-VHNLVVSNVPGPQLPLYL
MAB_1917|M.abscessus_ATCC_1997      LLQDWSQFAAPAVFGTAMRVYSRIRLADRHPVIHNLVVSNVPGPQVPLYF
Mb1791|M.bovis_AF2122/97            LLHDWIQFGGSTMFGAAMRILPHISITHSPA--YNLILSNVPGPQAQLYF
Rv1760|M.tuberculosis_H37Rv         LLHDWIQFGGSTMFGAAMRILPHISITHSPA--YNLILSNVPGPQAQLYF
Mflv_5212|M.gilvum_PYR-GCK          MLMDLAQSVSRTMFGWLLGGLSRTSLGNTAI--HNVIISNVAGPPTTLYS
MUL_1818|M.ulcerans_Agy99           QIMGLTETTPPGLLHLAARAYTATGLSHNLA-PINLVVSNVPGPQFPLYM
MLBr_01244|M.leprae_Br4923          SLAPLMTVLPASVLDFIVDSVASSDVNASNIPAYPGDTYFAGAKILRQYG
                                     :          ::       .   .              . .     * 

MSMEG_4297|M.smegmatis_MC2_155      LGAEVKAMYPLGPIFHGSGLNITVMSLTGKLDVGIISCPELLPDLWDMAD
Mvan_3601|M.vanbaalenii_PYR-1       LGCEVKAMYPLGPIFHGSGLNMTVMSLSGKLDVGIVSCPELLPDLWDMAD
TH_2477|M.thermoresistible__bu      LGAEVKAMYPLGPIFHGSGLNITVMSLTGRLNVGMVSCPELMPDLWELAE
MMAR_3298|M.marinum_M               LGCEVKAMYPLGPIFHGSGLNVTVMSLNGKLDVGLVACPELLPDLWQMAD
MAV_2240|M.avium_104                LGCEVKAMYPLGPIFHGSGLNITAMSLRGKLDVGLIGCPDLVPDLWELAD
MAB_1917|M.abscessus_ATCC_1997      LGAQVIGMYPLGPIFHGAALTVTVMSLDGKLNVGLISCPDLMPDLGTLTD
Mb1791|M.bovis_AF2122/97            LGCRMDSMFPLGPSLATRASTSPSCPSTGNWVSALSPAPTCCRTCGAWQT
Rv1760|M.tuberculosis_H37Rv         LGCRMDSMFPLGPLLGNAGLNITVMSLNGELGVGIVSCPDLLPDLWGVAD
Mflv_5212|M.gilvum_PYR-GCK          GGAEITGLYPLGPIFPGSGLNITVMSMGDKLNVGIISCPKLTDDLWDLAD
MUL_1818|M.ulcerans_Agy99           AGARLDSLVPLGPPVMDVALNITCFSYQEHLDFGFVTTPEVANDIDEMAD
MLBr_01244|M.leprae_Br4923          IGPRPGVAMMAVLMSRGGFCTVTVRYDRASVKSEALFARCLLEGFDEVLA
                                     * .                . .                           

MSMEG_4297|M.smegmatis_MC2_155      DFA-------VALDELLDATKRA---------
Mvan_3601|M.vanbaalenii_PYR-1       TFG-------VALQELLDATR-----------
TH_2477|M.thermoresistible__bu      GFE-------RALRELLDTVG-----------
MMAR_3298|M.marinum_M               EFA-------TVMEELLAETG-----------
MAV_2240|M.avium_104                EFA-------VAMEELRAAAR-----------
MAB_1917|M.abscessus_ATCC_1997      DFG-------VALEELKARI------------
Mb1791|M.bovis_AF2122/97            GFPRRSKSCWSAVMTSRKAATTRTPESYVQNR
Rv1760|M.tuberculosis_H37Rv         GFP-------EALKELLECSDDQPEGSNHQDS
Mflv_5212|M.gilvum_PYR-GCK          RFD-------AELADLLARS------------
MUL_1818|M.ulcerans_Agy99           LIEP-------ALAELERAAGL----------
MLBr_01244|M.leprae_Br4923          LAG---DPTPHAVPASFAARSSGSPAGWLSSS
                                                :