For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MKRLSSVDAAFWSAETAGWHMHVGALAICDPKGSAEYTFERLRQLLIERLPEVPQLRWRVTGAPLGLDRP WFVEDEELDVDFHLRRIGVPAPGGRRELEELVGRLMSYKLDRSRPLWEMWVIEGLDGNAGGRFATLTKMH HAIVDGVSGAGLGEILLDATPEPRPPQQETVGSLVGFQLPGLERRAVGALINVGVKTPFRIARLLEQTVR QQVATLGVRSRPPRYFEAPKTRFNAPVSPHRRVTGCRVELARAKAIKDAYDVKLNDVVLALVAGAVRDYL QKRGELPAKPLIAQIPVSTRTDENKDDIGNKVSSMTVSLATHIEDPGERLRAIHDSTQSAKLMAKALSAH QIMGLTETTPPGLLHLAARAYTASGLSRNLAPINLVVSNVPGPPFPLYMAGAKLDSLVPLGPPVMDVALN ITCFSYTDYLDFGFVTTPEVANDIDDMADRIEPALTDLEKAAAGETG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_3352 | - | - | 100% (468) | acyltransferase, ws/dgat/mgat subfamily protein |
| M. avium 104 | MAV_2240 | - | 1e-87 | 39.75% (473) | acyltransferase, ws/dgat/mgat subfamily protein |
| M. avium 104 | MAV_3015 | - | 5e-69 | 37.24% (427) | acyltransferase, ws/dgat/mgat subfamily protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1460 | - | 0.0 | 86.58% (462) | hypothetical protein Mb1460 |
| M. gilvum PYR-GCK | Mflv_0349 | - | 0.0 | 66.74% (460) | hypothetical protein Mflv_0349 |
| M. tuberculosis H37Rv | Rv1425 | - | 0.0 | 86.36% (462) | hypothetical protein Rv1425 |
| M. leprae Br4923 | MLBr_01244 | - | 7e-23 | 26.22% (389) | hypothetical protein MLBr_01244 |
| M. abscessus ATCC 19977 | MAB_0507 | - | 0.0 | 74.62% (461) | hypothetical protein MAB_0507 |
| M. marinum M | MMAR_2231 | - | 0.0 | 84.85% (462) | hypothetical protein MMAR_2231 |
| M. smegmatis MC2 155 | MSMEG_4297 | - | 5e-91 | 42.61% (467) | acyltransferase, ws/dgat/mgat subfamily protein |
| M. thermoresistible (build 8) | TH_2477 | - | 2e-85 | 41.58% (469) | PUTATIVE acyltransferase, ws/dgat/mgat subfamily protein |
| M. ulcerans Agy99 | MUL_1818 | - | 0.0 | 84.85% (462) | hypothetical protein MUL_1818 |
| M. vanbaalenii PYR-1 | Mvan_3601 | - | 5e-89 | 41.54% (467) | hypothetical protein Mvan_3601 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2231|M.marinum_M ---------------MRRLSSVDAAFWSAETAGWHMHVGALAICDPTDAP
MUL_1818|M.ulcerans_Agy99 ---------------MRRLSSVDAAFWSAETAGWHMHVGALAICDPTDAP
Mb1460|M.bovis_AF2122/97 ---------------MKRLSSVDAAFWSAETAGWHMHVGALAICDPSDAP
Rv1425|M.tuberculosis_H37Rv ---------------MKRLSSVDAAFWSAETAGWHMHVGALAICDPSDAP
MAV_3352|M.avium_104 --------------MMKRLSSVDAAFWSAETAGWHMHVGALAICDPKGSA
MAB_0507|M.abscessus_ATCC_1997 ---------------MQRLSGVDAAFWHAETAGWHMHIGGLSIYDPTDAP
Mflv_0349|M.gilvum_PYR-GCK ----------------MRLSSVDAAFWFAENLKWHMHIGAIALCDPSDVP
MSMEG_4297|M.smegmatis_MC2_155 ---------------MQRLSGLDASFLYLETAAQPMHVCSVLELDTSTMP
Mvan_3601|M.vanbaalenii_PYR-1 MDLLTPAPPRHTIGGMQRLSGLDASFLYLESAAQPLHVCSILELDTSTMP
TH_2477|M.thermoresistible__bu ------VPPPYDRG-MQRLSGLDASFLYLETPDQPLHVCSILELDTSTIP
MLBr_01244|M.leprae_Br4923 -----MADSVEGIGPFDELGALDYLLHRGEANPR-TRAGIMAVELLDTTP
.*..:* : * : : .
MMAR_2231|M.marinum_M -DYSFQRLRELLIERLPEIPQLRWRVTGAPLGLDRPWFVEDQDLDVDFHV
MUL_1818|M.ulcerans_Agy99 -DYSFQRLRELLIERLPEIPQLRWRVTGAPLGLDRPWFVEDQDLDVDFHV
Mb1460|M.bovis_AF2122/97 -EYSFQRLRELIIERLPEIPQLRWRVTGAPLGLDRPWFVEDEELDIDFHI
Rv1425|M.tuberculosis_H37Rv -EYSFQRLRELIIERLPEIPQLRWRVTGAPLGLDRPWFVEDEELDIDFHI
MAV_3352|M.avium_104 -EYTFERLRQLLIERLPEVPQLRWRVTGAPLGLDRPWFVEDEELDVDFHL
MAB_0507|M.abscessus_ATCC_1997 -DYSFERVRALIVERLPSMPQLRWRVTDVPLGLDRPWFVEDEELDPDFHI
Mflv_0349|M.gilvum_PYR-GCK -DFGFEQVRDLIISRLPELPQLRWRVVGAPLGLDRPYFVEDEDIDVDFHI
MSMEG_4297|M.smegmatis_MC2_155 GGYTFDRLRDALSLRIKAMPEFREKLADSRFNLDHPVWVEDNDFDVDRHL
Mvan_3601|M.vanbaalenii_PYR-1 GGYTFDRLRDGLALRIKAMPEFREKIADSRFNLDHPVWVEDNDFDVDRHL
TH_2477|M.thermoresistible__bu GGYDFHQLREALLLRIKAMPEFREKLADNRFNLDHPVWVEDADFDVDRHL
MLBr_01244|M.leprae_Br4923 ---DWNRFRSRIEDVSQRVLRLRQKVVVPTLPTAAPRWVVDPDFELDFHV
:.:.* : : .:* ::. : * :* * ::: * *:
MMAR_2231|M.marinum_M RRIGVPAPGGRRELEELVGRLMSYKLDRSRPLWELWVIEGVE------GG
MUL_1818|M.ulcerans_Agy99 RRIGVPAPGGRRELEELVGRLMSYKLDRSRPLWELWVIEGVE------GG
Mb1460|M.bovis_AF2122/97 RRIGVPAPGGRRELEELVGRLMSYKLDRSRPLWELWVIEGVE------GG
Rv1425|M.tuberculosis_H37Rv RRIGVPAPGGRRELEELVGRLMSYKLDRSRPLWELWVIEGVE------GG
MAV_3352|M.avium_104 RRIGVPAPGGRRELEELVGRLMSYKLDRSRPLWEMWVIEGLDGN---AGG
MAB_0507|M.abscessus_ATCC_1997 RRIGVPAPGGRKELEELAGRLMSYKLDRSRPLWELWVIEGVE------GG
Mflv_0349|M.gilvum_PYR-GCK RRIAVPSPGGRKELDDLVGRLMSYKLDRSKPLWELWFIEGLE------GG
MSMEG_4297|M.smegmatis_MC2_155 HRIGLPGPGGRAELAEICGHIASLPLDRSRPLWEMWVIENVAGTDAHAGG
Mvan_3601|M.vanbaalenii_PYR-1 HRIGLPSPGGRVELAEICGHIASLPLDRTRPLWEMWVIENVAGTDAHAGG
TH_2477|M.thermoresistible__bu HRIGLPAPGGPAELAEICGHLAALPLDRSRPLWEMWVIENIDGTDPRSGG
MLBr_01244|M.leprae_Br4923 RRVRVPDPGTLREVFDLAEVIQQSPMDVSRPLWTATLVEGLA------AG
:*: :* ** *: :: : :* ::*** .:*.: .*
MMAR_2231|M.marinum_M RIATLTKMHHAIVDGVSGAGLGEILLDVTPEP-------RPPQEETVG-F
MUL_1818|M.ulcerans_Agy99 RIATLTKMHHAIVDGVSGAGLGEILLDVTPEP-------RPPQEETVG-F
Mb1460|M.bovis_AF2122/97 RIATLTKMHHAIVDGVSGAGLGEILLDITPEP-------RPPQQETVG-F
Rv1425|M.tuberculosis_H37Rv RIATLTKMHHAIVDGVSGAGLGEILLDITPEP-------RPPQQETVG-F
MAV_3352|M.avium_104 RFATLTKMHHAIVDGVSGAGLGEILLDATPEP-------RPPQQETVGSL
MAB_0507|M.abscessus_ATCC_1997 RVATLTKMHHAIVDGVSGAGLGEILLDIAPEP-------RPAPDDTVGSL
Mflv_0349|M.gilvum_PYR-GCK RVAVVTKMHHAVVDGVSGAGISEILLDTTPEP-------RPPAVDASRSL
MSMEG_4297|M.smegmatis_MC2_155 RLALMTKVHHASVDGVTGANLLSQLCTTEPDA-------PPP--DPVD--
Mvan_3601|M.vanbaalenii_PYR-1 RIAVMTKVHHAAVDGVTGANLMSKLCTTEPDA-------PPP--DPVA--
TH_2477|M.thermoresistible__bu PLVVLTKVHHAAVDGVTGANLLSQVCTTEADT-------PPP--EPVQ--
MLBr_01244|M.leprae_Br4923 RAAMLLQISHAITDGVGSVEMFAEMYDLERDPPSRPRSPQPIPQDLSRND
. : :: ** .*** .. : : :. * :
MMAR_2231|M.marinum_M VGFQIPRLERRAVGALINVGIMTPFRIAR-LVEQTVRQQIAALGVSARP-
MUL_1818|M.ulcerans_Agy99 VGFQIPRLERRAVGALINVGIMTPFRIAR-LVEQTVRQQIAALGVSARP-
Mb1460|M.bovis_AF2122/97 VGFQIPGLERRAIGALINVGIMTPFRIVR-LLEQTVRQQIAALGVAGKP-
Rv1425|M.tuberculosis_H37Rv VGFQIPGLERRAIGALINVGIMTPFRIVR-LLEQTVRQQIAALGVAGKP-
MAV_3352|M.avium_104 VGFQLPGLERRAVGALINVGVKTPFRIAR-LLEQTVRQQVATLGVRSRP-
MAB_0507|M.abscessus_ATCC_1997 VGLGLPSRERILLSALVNVGVKTPYRVAR-LVQQTVRQQLAVFGMERKS-
Mflv_0349|M.gilvum_PYR-GCK VGVKPPSRERQAVNGLINVWFKTPYRITR-LLEQTVRQQIAVRNIDNKP-
MSMEG_4297|M.smegmatis_MC2_155 -GPGGGTGLEIAVNGAVRFATR-PLRLVN-VVPSTLNTVVDTVRRARNGR
Mvan_3601|M.vanbaalenii_PYR-1 -GPGGGTDLEIAVSGAVRFATR-PLKLVN-VVPNTVSTVIDTVKRARNGL
TH_2477|M.thermoresistible__bu -GAGTASDLEIALSGAVRFATR-PLKLLN-VLPTTANSVLDTVRRARAGR
MLBr_01244|M.leprae_Br4923 LMLQGINHLPVALAGGVVGGLSGVASVAGRAILRPASTVSGVVGYVRSGI
: . : : : . .
MMAR_2231|M.marinum_M --PRYFDAPKTRFNAHVSPHRRVSGCRIELARAKAVKDAFGVKLNDVVLA
MUL_1818|M.ulcerans_Agy99 --PRYFDAPKTRFNAHVSPHRRVSGCRIELARAKAVKDAFGVKLNDVVLA
Mb1460|M.bovis_AF2122/97 --ARYFEAPKTRFNAPVSPHRRVTGTRVELARAKAVKDAFGVKLNDVVLA
Rv1425|M.tuberculosis_H37Rv --ARYFEAPKTRFNAPVSPHRRVTGTRVELARAKAVKDAFGVKLNDVVLA
MAV_3352|M.avium_104 --PRYFEAPKTRFNAPVSPHRRVTGCRVELARAKAIKDAYDVKLNDVVLA
MAB_0507|M.abscessus_ATCC_1997 --PGYFEAPHTRFNAPVSPHRRISGARLDLARVKALKDAFGVKVNDVVLA
Mflv_0349|M.gilvum_PYR-GCK --PRYFDAPKVRFNGPISPHRSVAGASVPLDRVKAVKNAFDVKLNDVVLA
MSMEG_4297|M.smegmatis_MC2_155 TMAAPFAAPRTAFNANITGHRNIAFAQLDLEDIKTVKNHFDVKVNDVVMA
Mvan_3601|M.vanbaalenii_PYR-1 TMAPPFAAPKTAFNANVTGHRNVAFAQLDLEDIKTVKNHFGVKVNDVVMA
TH_2477|M.thermoresistible__bu TMARPFAAPSTPFNANVTGRRNVAFTQLDLEDVKRIKDHFGVKVNDVVMA
MLBr_01244|M.leprae_Br4923 RVLSQAAEPSPLLRQRSLATR-TEAIEIQLSDLHKAAKAGDGSINDAYLA
* :. * : * : . . .:**. :*
MMAR_2231|M.marinum_M TVAGAAREYLKKRDELPAKPLIAQIPVSTRTDQTKEDVGNQISSMTASLA
MUL_1818|M.ulcerans_Agy99 TVAGAAREYLKKRDELPAKPLIAQIPVSTRTDQTKEDVGNQISSMTASLA
Mb1460|M.bovis_AF2122/97 LVAGAARQYLQKRDELPAKPLIAQIPVSTRSEETKADVGNQVSSMTASLA
Rv1425|M.tuberculosis_H37Rv LVAGAARQYLQKRDELPAKPLIAQIPVSTRSEETKADVGNQVSSMTASLA
MAV_3352|M.avium_104 LVAGAVRDYLQKRGELPAKPLIAQIPVSTRTDENKDDIGNKVSSMTVSLA
MAB_0507|M.abscessus_ATCC_1997 IVAGAVRDYLAKRDEFPDKPLIVQIPVSVRTEETDGVVGNQVSSMTVSLA
Mflv_0349|M.gilvum_PYR-GCK LVSGALRSYLKDRGELPAKSLVSQVPVSTR-AQADDTVGNQVNAMTVVLA
MSMEG_4297|M.smegmatis_MC2_155 LVSGVLRTFLSHRDELPDNSLVAMVPVSVH-DRSDRPGRNQVSGMFSPLQ
Mvan_3601|M.vanbaalenii_PYR-1 LVSGVLRTFLLERGELPESSLVAMVPVSVH-DKSDRPGRNQVSGMFSRLE
TH_2477|M.thermoresistible__bu LTSGALRSYLLERDQLPDSPLIAMVPVSVH-DKTDRPGRNHVSGMFSRLE
MLBr_01244|M.leprae_Br4923 GLVGALRRYHEALG-VSISTLPMAVPVNVR-TEADVVGSNRFVGVTLAAP
*. * : . .. ..* :**..: . . *:. .:
MMAR_2231|M.marinum_M THINDPAERLKAIHESTQNAKEMAKALSAHQIMGLTETTPPGLLHLAARA
MUL_1818|M.ulcerans_Agy99 THINDPAERLKAIHESTQNAKEMAKALSAHQIMGLTETTPPGLLHLAARA
Mb1460|M.bovis_AF2122/97 THIEDPAKRLAAIHESTLSAKEMAKALSAHQIMGLTETTPPGLLQLAARA
Rv1425|M.tuberculosis_H37Rv THIEDPAKRLAAIHESTLSAKEMAKAPSAHQIMGLTETTPPGLLQLAARA
MAV_3352|M.avium_104 THIEDPGERLRAIHDSTQSAKLMAKALSAHQIMGLTETTPPGLLHLAARA
MAB_0507|M.abscessus_ATCC_1997 TDIDDPAERIQAIYEGTQGAKEMARAMSAHQIMGLTDTTPPGLLQLAARA
Mflv_0349|M.gilvum_PYR-GCK TDVADPAERIKAIYSYTQGAKEMTKALTAHQIMGYTETTPPGLLALASRA
MSMEG_4297|M.smegmatis_MC2_155 THIADPAERLRAIAEANAVAKQHSSAIGATLLQDWTQFAAPAVFGTAMRV
Mvan_3601|M.vanbaalenii_PYR-1 TNIEDPATRLKAIAEANSVAKQHSSAIAATLLQDWTQFAAPAVFGAAMRV
TH_2477|M.thermoresistible__bu TTIEDPAERLRAIANANSVAKQHSSAIAASLLQDWTQFAAPAVFGVAMRV
MLBr_01244|M.leprae_Br4923 LGTNDPAARMQKIRSQMTQRRDEPAMNIIGSLAPLMTVLPASVLDFIVDS
**. *: * . : . : ...::
MMAR_2231|M.marinum_M YTATGLSHNLAPINLVVSNVPGPQFPLYMAGARLDSLVPLGPPVMDVALN
MUL_1818|M.ulcerans_Agy99 YTATGLSHNLAPINLVVSNVPGPQFPLYMAGARLDSLVPLGPPVMDVALN
Mb1460|M.bovis_AF2122/97 YTASGLSHNLAPINLVVSNVPGPPFPLYMAGARLDSLVPLGPPVMDVALN
Rv1425|M.tuberculosis_H37Rv YTASGLSHNLAPINLVVSNVPGPPFPLYMAGARLDSLVPLGPPVMDVALN
MAV_3352|M.avium_104 YTASGLSRNLAPINLVVSNVPGPPFPLYMAGAKLDSLVPLGPPVMDVALN
MAB_0507|M.abscessus_ATCC_1997 YTASGLSRNLAPINLVLSNVPGPSFPLYMAGARLESMIPLGPPVMDVALN
Mflv_0349|M.gilvum_PYR-GCK YAASGIGSNIAPMNVVISNVPGPTFPLYLGGARVEHLMPVGPLLFDVALN
MSMEG_4297|M.smegmatis_MC2_155 YAASRLSGAKPVHNLVVSNVPGPQVPLYFLGAEVKAMYPLGPIFHGSGLN
Mvan_3601|M.vanbaalenii_PYR-1 YASSRLSGARPVHNLVISNVPGPQGPLYMLGCEVKAMYPLGPIFHGSGLN
TH_2477|M.thermoresistible__bu YAASRLGEAKPVHNLVVSNVPGPQVPLYFLGAEVKAMYPLGPIFHGSGLN
MLBr_01244|M.leprae_Br4923 VASS---------DVNASNIPAYPGDTYFAGAKILRQYGIGP-RPGVAMM
::: :: **:*. *: *..: :** . .:
MMAR_2231|M.marinum_M ITCFSYQEHLDFGFVTTPEVANDIDEMADLIEPALAELERAAGL------
MUL_1818|M.ulcerans_Agy99 ITCFSYQEHLDFGFVTTPEVANDIDEMADLIEPALAELERAAGL------
Mb1460|M.bovis_AF2122/97 ITCFSYQDYLDFGLVTTPEVANDIDEMADAIEPALAELERAAE-------
Rv1425|M.tuberculosis_H37Rv ITCFSYQDYLDFGLVTTPEVANDIDEMADAIEPALAELERAAE-------
MAV_3352|M.avium_104 ITCFSYTDYLDFGFVTTPEVANDIDDMADRIEPALTDLEKAAAGETG---
MAB_0507|M.abscessus_ATCC_1997 ITCFSYLEHMDFGFVTTPEVAADIDEMADGLEAALVELEHAVGI------
Mflv_0349|M.gilvum_PYR-GCK VTCFSYCGAVDFGFITTPEIAADIVDLADQIEPALHDLEVAAGLVSDPTR
MSMEG_4297|M.smegmatis_MC2_155 ITVMSLTGKLDVGIISCPELLPDLWDMADDFAVALDELLDATKRA-----
Mvan_3601|M.vanbaalenii_PYR-1 MTVMSLSGKLDVGIVSCPELLPDLWDMADTFGVALQELLDATR-------
TH_2477|M.thermoresistible__bu ITVMSLTGRLNVGMVSCPELMPDLWELAEGFERALRELLDTVG-------
MLBr_01244|M.leprae_Br4923 AVLMSRGGFCTVTVRYDRASVKSEALFARCLLEGFDEVLALAGDPTPHAV
. :* . . . :* : .: :: .
MMAR_2231|M.marinum_M -------------------
MUL_1818|M.ulcerans_Agy99 -------------------
Mb1460|M.bovis_AF2122/97 -------------------
Rv1425|M.tuberculosis_H37Rv -------------------
MAV_3352|M.avium_104 -------------------
MAB_0507|M.abscessus_ATCC_1997 -------------------
Mflv_0349|M.gilvum_PYR-GCK PKPRKRGRR----------
MSMEG_4297|M.smegmatis_MC2_155 -------------------
Mvan_3601|M.vanbaalenii_PYR-1 -------------------
TH_2477|M.thermoresistible__bu -------------------
MLBr_01244|M.leprae_Br4923 PASFAARSSGSPAGWLSSS