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DLLTPAPPRHTIGGMQRLSGLDASFLYLESAAQPLHVCSILELDTSTMPGGYTFDRLRDGLALRIKAMPE FREKIADSRFNLDHPVWVEDNDFDVDRHLHRIGLPSPGGRVELAEICGHIASLPLDRTRPLWEMWVIENV AGTDAHAGGRIAVMTKVHHAAVDGVTGANLMSKLCTTEPDAPPPDPVAGPGGGTDLEIAVSGAVRFATRP LKLVNVVPNTVSTVIDTVKRARNGLTMAPPFAAPKTAFNANVTGHRNVAFAQLDLEDIKTVKNHFGVKVN DVVMALVSGVLRTFLLERGELPESSLVAMVPVSVHDKSDRPGRNQVSGMFSRLETNIEDPATRLKAIAEA NSVAKQHSSAIAATLLQDWTQFAAPAVFGAAMRVYASSRLSGARPVHNLVISNVPGPQGPLYMLGCEVKA MYPLGPIFHGSGLNMTVMSLSGKLDVGIVSCPELLPDLWDMADTFGVALQELLDATR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3601 | - | - | 100% (478) | hypothetical protein Mvan_3601 |
| M. vanbaalenii PYR-1 | Mvan_1065 | - | e-156 | 59.69% (459) | hypothetical protein Mvan_1065 |
| M. vanbaalenii PYR-1 | Mvan_2253 | - | 7e-65 | 34.48% (464) | hypothetical protein Mvan_2253 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1791 | - | 1e-144 | 59.71% (412) | hypothetical protein Mb1791 |
| M. gilvum PYR-GCK | Mflv_5212 | - | 1e-154 | 58.17% (459) | hypothetical protein Mflv_5212 |
| M. tuberculosis H37Rv | Rv1760 | - | 1e-162 | 59.74% (462) | hypothetical protein Rv1760 |
| M. leprae Br4923 | MLBr_01244 | - | 2e-25 | 24.19% (430) | hypothetical protein MLBr_01244 |
| M. abscessus ATCC 19977 | MAB_1917 | - | 0.0 | 65.80% (459) | hypothetical protein MAB_1917 |
| M. marinum M | MMAR_3298 | - | 0.0 | 78.14% (462) | hypothetical protein MMAR_3298 |
| M. avium 104 | MAV_2240 | - | 0.0 | 72.35% (463) | acyltransferase, ws/dgat/mgat subfamily protein |
| M. smegmatis MC2 155 | MSMEG_4297 | - | 0.0 | 87.69% (463) | acyltransferase, ws/dgat/mgat subfamily protein |
| M. thermoresistible (build 8) | TH_2477 | - | 0.0 | 78.96% (461) | PUTATIVE acyltransferase, ws/dgat/mgat subfamily protein |
| M. ulcerans Agy99 | MUL_1818 | - | 7e-90 | 41.85% (466) | hypothetical protein MUL_1818 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_3601|M.vanbaalenii_PYR-1 -------------------MDLLTPAPPRHTIGGMQRLSGLDASFLYLES
MSMEG_4297|M.smegmatis_MC2_155 ----------------------------------MQRLSGLDASFLYLET
TH_2477|M.thermoresistible__bu -------------------------VPPPYDRG-MQRLSGLDASFLYLET
MMAR_3298|M.marinum_M ----------------------------------MQRLSGLDASFLYLET
MAV_2240|M.avium_104 -------------------------------MLRMQRLSGLDASFLYLET
MAB_1917|M.abscessus_ATCC_1997 ----------------------------------MQRLSGLDASFLYLET
Mb1791|M.bovis_AF2122/97 MPRGCAGARFACNACLNFLAGLGISEPISPGWAAMERLSGLDAFFLYMET
Rv1760|M.tuberculosis_H37Rv MPRGCAGARFACNACLNFLAGLGISEPISPGWAAMERLSGLDAFFLYMET
Mflv_5212|M.gilvum_PYR-GCK ----------------------------------MERLSGLDAGMLYSES
MUL_1818|M.ulcerans_Agy99 ----------------------------------MRRLSSVDAAFWSAET
MLBr_01244|M.leprae_Br4923 ------------------------MADSVEGIGPFDELGALDYLLHRGEA
: .*..:* : *:
Mvan_3601|M.vanbaalenii_PYR-1 -AAQPLHVCSILELDTSTMPGGYTFDRLRDGLALRIKAMPEFREKIADSR
MSMEG_4297|M.smegmatis_MC2_155 -AAQPMHVCSVLELDTSTMPGGYTFDRLRDALSLRIKAMPEFREKLADSR
TH_2477|M.thermoresistible__bu -PDQPLHVCSILELDTSTIPGGYDFHQLREALLLRIKAMPEFREKLADNR
MMAR_3298|M.marinum_M -SNQPMHVCSIMELDTSTMPGGYTFDRLQDALALRIKAMPEFREKLANSA
MAV_2240|M.avium_104 -SSQPMHVCSIIELDTSTVPGGYTFERLRDALVRRIRAVPPFREKLADSP
MAB_1917|M.abscessus_ATCC_1997 -PTQPMHVCGVLELDTTTIPGGYSFEKLRTKLAERVEGIPSFREKLADSR
Mb1791|M.bovis_AF2122/97 -PSQPLNVCCVLELDTSTMPGGYTYGRFHAALEKYVKAAPEFRMKLADTE
Rv1760|M.tuberculosis_H37Rv -PSQPLNVCCVLELDTSTMPGGYTYGRFHAALEKYVKAAPEFRMKLADTE
Mflv_5212|M.gilvum_PYR-GCK -PTVPLHVCSVTELDTSTVPGGYTFAKFRDHLASRVPAIPEFRTKLADND
MUL_1818|M.ulcerans_Agy99 -AGWHMHVGALAICDPTDAP-DYSFQRLRELLIERLPEIPQLRWRVTGAP
MLBr_01244|M.leprae_Br4923 NPRTRAGIMAVELLDT-----TPDWNRFRSRIEDVSQRVLRLRQKVVVPT
. : : *. : ::: : :* ::.
Mvan_3601|M.vanbaalenii_PYR-1 FNLDHPVWVEDNDFDVDRHLHRIGLPSPGGRVELAEICGHIASLPLDRTR
MSMEG_4297|M.smegmatis_MC2_155 FNLDHPVWVEDNDFDVDRHLHRIGLPGPGGRAELAEICGHIASLPLDRSR
TH_2477|M.thermoresistible__bu FNLDHPVWVEDADFDVDRHLHRIGLPAPGGPAELAEICGHLAALPLDRSR
MMAR_3298|M.marinum_M LNLDHPVWVDDEDFQLHRHLHRIGLPPPGGRAELSQICGHIASLPLDRSR
MAV_2240|M.avium_104 LNLDHPVWVDDEDFDVDRHLHRIAVPAPGGRAELSQICGHIAQTPLDRRR
MAB_1917|M.abscessus_ATCC_1997 LNLDHPVWVDDDDFDIDRHLHHVGLPAPGGKAEIADMCGHIASLPLDRAR
Mb1791|M.bovis_AF2122/97 LNLDHPVWVDDDNFQIRHHLRRVAMPAPGGRRELAEICGYIAGLPLDRDR
Rv1760|M.tuberculosis_H37Rv LNLDHPVWVDDDNFQIRHHLRRVAMPAPGGRRELAEICGYIAGLPLDRDR
Mflv_5212|M.gilvum_PYR-GCK LNFDHPVWVEDDDFDLTRHLNRVALPEPGGRDELAELCGRLIGMPLERSK
MUL_1818|M.ulcerans_Agy99 LGLDRPWFVEDQDLDVDFHVRRIGVPAPGGRRELEELVGRLMSYKLDRSR
MLBr_01244|M.leprae_Br4923 LPTAAPRWVVDPDFELDFHVRRVRVPDPGTLREVFDLAEVIQQSPMDVSR
: * :* * :::: *:.:: :* ** *: :: : :: :
Mvan_3601|M.vanbaalenii_PYR-1 PLWEMWVIENVAGTDAHAGGRIAVMTKVHHAAVDGVTGANLMSKLCTTEP
MSMEG_4297|M.smegmatis_MC2_155 PLWEMWVIENVAGTDAHAGGRLALMTKVHHASVDGVTGANLLSQLCTTEP
TH_2477|M.thermoresistible__bu PLWEMWVIENIDGTDPRSGGPLVVLTKVHHAAVDGVTGANLLSQVCTTEA
MMAR_3298|M.marinum_M PLWEMWVIEGVAGTDCHHDGRLAVLTKVHHAAVDGVTGANLMSQLCTTEA
MAV_2240|M.avium_104 PLWEMWVIEGVAGTDCHRDGRLAVMTKVHHAGVDGVTGANLMSQLCATEP
MAB_1917|M.abscessus_ATCC_1997 PLWEMWVIETGDTN------RLVVMTKMHHASVDGVTGANLMSALCGLEP
Mb1791|M.bovis_AF2122/97 PLWEMWVIEGGARSD-----TVAVMLKVHHAVVDGVAGANLLSHLCSLQP
Rv1760|M.tuberculosis_H37Rv PLWEMWVIEGGARSD-----TVAVMLKVHHAVVDGVAGANLLSHLCSLQP
Mflv_5212|M.gilvum_PYR-GCK PLWEMWVIEGVGGSAAREDGRLALLLKVHHAAVDGVSAADLLAKLLDTEP
MUL_1818|M.ulcerans_Agy99 PLWELWVIEGVEGG------RIATLTKMHHAIVDGVSGAGLGEILLDVTP
MLBr_01244|M.leprae_Br4923 PLWTATLVEGLAAG------RAAMLLQISHAITDGVGSVEMFAEMYDLER
*** ::* . : :: ** .*** .. : :
Mvan_3601|M.vanbaalenii_PYR-1 DAPPP--DPVAGPGGGTDLEIAVSGAVRFATR------------PLKLVN
MSMEG_4297|M.smegmatis_MC2_155 DAPPP--DPVDGPGGGTGLEIAVNGAVRFATR------------PLRLVN
TH_2477|M.thermoresistible__bu DTPPP--EPVQGAGTASDLEIALSGAVRFATR------------PLKLLN
MMAR_3298|M.marinum_M DAPAP--DPVDGVGGATDWQIAAGGLLRFATR------------PLQLAN
MAV_2240|M.avium_104 DAAPP--EPAAGVGGGAGWRIAAGGLVRFAAR------------PLRLAS
MAB_1917|M.abscessus_ATCC_1997 DAEAP--EPAPGVGGANSLEIAVTGALKWASR------------PLKFAK
Mb1791|M.bovis_AF2122/97 DAPAP--QPVRGTGGGNVLQIAASGLVGFASR------------PVRLAT
Rv1760|M.tuberculosis_H37Rv DAPAP--QPVRGTGGGNVLQIAASGLEGFASR------------PVRLAT
Mflv_5212|M.gilvum_PYR-GCK DAPPP--DPVDAPTGASTWEIAADGLWRVATR------------PWQLTR
MUL_1818|M.ulcerans_Agy99 EPRPPQ-EETVGFVGFQIPRLERRAVGALINVGIM--------TPFRIAR
MLBr_01244|M.leprae_Br4923 DPPSRPRSPQPIPQDLSRNDLMLQGINHLPVALAGGVVGGLSGVASVAGR
:. . . : . .
Mvan_3601|M.vanbaalenii_PYR-1 VVPNTVSTVIDTVKRARNGLTMAPPFAAPKTAFNANVTGHRNVAFAQLDL
MSMEG_4297|M.smegmatis_MC2_155 VVPSTLNTVVDTVRRARNGRTMAAPFAAPRTAFNANITGHRNIAFAQLDL
TH_2477|M.thermoresistible__bu VLPTTANSVLDTVRRARAGRTMARPFAAPSTPFNANVTGRRNVAFTQLDL
MMAR_3298|M.marinum_M VVPETVSSVVSTLLRAREGLTMARPFTAPRTVFNARVSGRRAVAYAELDL
MAV_2240|M.avium_104 VVPDTAASVLATVRRALDGAAMARPFAAPTTVFNARISNRRCIAYAELNL
MAB_1917|M.abscessus_ATCC_1997 LLPATIGVIPAWLERSKRGEAMSAPFSAPRTSFNSTITSRRNVGYAQLDL
Mb1791|M.bovis_AF2122/97 VVPATVLTLVRTLLRAREGRTMAAPFSAPPTPFNGPLGRLRNIAYTQLDM
Rv1760|M.tuberculosis_H37Rv VVPATVLTLVRTLLRAREGRTMAAPFSAPPTPFNGPLGRLRNIAYTQLDM
Mflv_5212|M.gilvum_PYR-GCK VVPVATSLVTNTVSRALSGTAMALPFSAPSTPFNAPLTSDRNIAFAQLDL
MUL_1818|M.ulcerans_Agy99 LVEQTVRQQIAALGVSARP---PRYFDAPKTRFNAHVSPHRRVSGCRIEL
MLBr_01244|M.leprae_Br4923 AILRPASTVSGVVGYVRSGIRVLSQAAEPSPLLRQRSLATR-TEAIEIQL
: . : * . :. * .:::
Mvan_3601|M.vanbaalenii_PYR-1 EDIKTVKNHFGVKVNDVVMALVSGVLRTFLLERGELPESSLVAMVPVSVH
MSMEG_4297|M.smegmatis_MC2_155 EDIKTVKNHFDVKVNDVVMALVSGVLRTFLSHRDELPDNSLVAMVPVSVH
TH_2477|M.thermoresistible__bu EDVKRIKDHFGVKVNDVVMALTSGALRSYLLERDQLPDSPLIAMVPVSVH
MMAR_3298|M.marinum_M EDIKAVKNHFGVKVNDVVMGLVSGVLRNYLADRDALPTSSLVASVPVSVH
MAV_2240|M.avium_104 DDVKAVKNHFGVKVNDVVMALVSGVLRQYLAERNALPDSSLVASVPISVH
MAB_1917|M.abscessus_ATCC_1997 EDVRTVKNHFGVKVNDVVMAICAGALRKYLDDRGELPDNSLVAMVPVSVH
Mb1791|M.bovis_AF2122/97 RDVKRVKDRFGVTINDVVVALCAGALRRFLLEHGVLPEAPLVATVPVSVH
Rv1760|M.tuberculosis_H37Rv RDVKRVKDRFGVTINDVVVALCAGALRRFLLEHGVLPEAPLVATVPVSVH
Mflv_5212|M.gilvum_PYR-GCK DDVKKVKNQAEVKVNDVVMALCAGALRGYLDERGALPDKPLIAVVPSSVH
MUL_1818|M.ulcerans_Agy99 ARAKAVKDAFGVKLNDVVLATVAGAAREYLKKRDELPAKPLIAQIPVSTR
MLBr_01244|M.leprae_Br4923 SDLHKAAKAGDGSINDAYLAGLVGALRRYHEALG-VSISTLPMAVPVNVR
: . .:**. :. *. * : . :. .* :* ..:
Mvan_3601|M.vanbaalenii_PYR-1 DKSDRPGR-NQVSGMFSRLETNIEDPATRLKAIAEANSVAKQHSSAIAAT
MSMEG_4297|M.smegmatis_MC2_155 DRSDRPGR-NQVSGMFSPLQTHIADPAERLRAIAEANAVAKQHSSAIGAT
TH_2477|M.thermoresistible__bu DKTDRPGR-NHVSGMFSRLETTIEDPAERLRAIANANSVAKQHSSAIAAS
MMAR_3298|M.marinum_M GKSDRPGR-NQVSAMFSSLHTEIADPAERLNAIAHGNTVAKGHSSAIGAT
MAV_2240|M.avium_104 GKSDRPGR-NQVSAMFASLHTEIADPVQRLKAIAHANSLAKEHSSAIGAS
MAB_1917|M.abscessus_ATCC_1997 EKSDRPGR-NQVSGMFSRLETNVDDPVERLNAIAAANNIAKDHTAVLGAT
Mb1791|M.bovis_AF2122/97 DKSDRPGR-NQATWMFCRVPSQISDPAQRIRTIAAGNTVAKDHAAAIGPT
Rv1760|M.tuberculosis_H37Rv DKSDRPGR-NQATWMFCRVPSQISDPAQRIRTIAAGNTVAKDHAAAIGPT
Mflv_5212|M.gilvum_PYR-GCK GQTDRPGR-NQLSGMFCNLHTDIEDPLDRLYAIGASNVRAKEHSGSLGPS
MUL_1818|M.ulcerans_Agy99 TDQTKEDVGNQISSMTASLATHINDPAERLKAIHESTQNAKEMAKALSAH
MLBr_01244|M.leprae_Br4923 TEADVVGS-NRFVGVTLAAPLGTNDPAARMQKIRSQMTQRRDEPAMNIIG
. *: : ** *: * : .
Mvan_3601|M.vanbaalenii_PYR-1 LLQDWTQFAAPAVFGAAMRVYASSRLSGARP-VHNLVISNVPGPQGPLYM
MSMEG_4297|M.smegmatis_MC2_155 LLQDWTQFAAPAVFGTAMRVYAASRLSGAKP-VHNLVVSNVPGPQVPLYF
TH_2477|M.thermoresistible__bu LLQDWTQFAAPAVFGVAMRVYAASRLGEAKP-VHNLVVSNVPGPQVPLYF
MMAR_3298|M.marinum_M LLQDWSQFAAPAVFGAAMRVYASSRLTESLP-VHNLVVSNVPGPQLPLYM
MAV_2240|M.avium_104 LLQDWTQFAAPAVFGIAMRLYARTRFTDSMP-VHNLVVSNVPGPQLPLYL
MAB_1917|M.abscessus_ATCC_1997 LLQDWSQFAAPAVFGTAMRVYSRIRLADRHPVIHNLVVSNVPGPQVPLYF
Mb1791|M.bovis_AF2122/97 LLHDWIQFGGSTMFGAAMRILPHISITHSPA--YNLILSNVPGPQAQLYF
Rv1760|M.tuberculosis_H37Rv LLHDWIQFGGSTMFGAAMRILPHISITHSPA--YNLILSNVPGPQAQLYF
Mflv_5212|M.gilvum_PYR-GCK MLMDLAQSVSRTMFGWLLGGLSRTSLGNTAI--HNVIISNVAGPPTTLYS
MUL_1818|M.ulcerans_Agy99 QIMGLTETTPPGLLHLAARAYTATGLSHNLA-PINLVVSNVPGPQFPLYM
MLBr_01244|M.leprae_Br4923 SLAPLMTVLPASVLDFIVDSVASSDVNASNIPAYPGDTYFAGAKILRQYG
: :: . . . . *
Mvan_3601|M.vanbaalenii_PYR-1 LGCEVKAMYPLGPIFHGSGLNMTVMSLSGKLDVGIVSCPELLPDLWDMAD
MSMEG_4297|M.smegmatis_MC2_155 LGAEVKAMYPLGPIFHGSGLNITVMSLTGKLDVGIISCPELLPDLWDMAD
TH_2477|M.thermoresistible__bu LGAEVKAMYPLGPIFHGSGLNITVMSLTGRLNVGMVSCPELMPDLWELAE
MMAR_3298|M.marinum_M LGCEVKAMYPLGPIFHGSGLNVTVMSLNGKLDVGLVACPELLPDLWQMAD
MAV_2240|M.avium_104 LGCEVKAMYPLGPIFHGSGLNITAMSLRGKLDVGLIGCPDLVPDLWELAD
MAB_1917|M.abscessus_ATCC_1997 LGAQVIGMYPLGPIFHGAALTVTVMSLDGKLNVGLISCPDLMPDLGTLTD
Mb1791|M.bovis_AF2122/97 LGCRMDSMFPLGPSLATRASTSPSCPSTGNWVSALSPAPTCCRTCGAWQT
Rv1760|M.tuberculosis_H37Rv LGCRMDSMFPLGPLLGNAGLNITVMSLNGELGVGIVSCPDLLPDLWGVAD
Mflv_5212|M.gilvum_PYR-GCK GGAEITGLYPLGPIFPGSGLNITVMSMGDKLNVGIISCPKLTDDLWDLAD
MUL_1818|M.ulcerans_Agy99 AGARLDSLVPLGPPVMDVALNITCFSYQEHLDFGFVTTPEVANDIDEMAD
MLBr_01244|M.leprae_Br4923 IGPRPGVAMMAVLMSRGGFCTVTVRYDRASVKSEALFARCLLEGFDEVLA
* . . .
Mvan_3601|M.vanbaalenii_PYR-1 TFG-------VALQELLDATR-----------
MSMEG_4297|M.smegmatis_MC2_155 DFA-------VALDELLDATKRA---------
TH_2477|M.thermoresistible__bu GFE-------RALRELLDTVG-----------
MMAR_3298|M.marinum_M EFA-------TVMEELLAETG-----------
MAV_2240|M.avium_104 EFA-------VAMEELRAAAR-----------
MAB_1917|M.abscessus_ATCC_1997 DFG-------VALEELKARI------------
Mb1791|M.bovis_AF2122/97 GFPRRSKSCWSAVMTSRKAATTRTPESYVQNR
Rv1760|M.tuberculosis_H37Rv GFP-------EALKELLECSDDQPEGSNHQDS
Mflv_5212|M.gilvum_PYR-GCK RFD-------AELADLLARS------------
MUL_1818|M.ulcerans_Agy99 LIEP-------ALAELERAAGL----------
MLBr_01244|M.leprae_Br4923 LAG---DPTPHAVPASFAARSSGSPAGWLSSS
: