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MTTPLSRQQEHRLLSRFMLLSLAAAIVTMALKAGAAVITGSVGFLSDALESGVNLVAAVVALWALRVAAR PRDADHHFGHGKAEYLSALVEGAMIFVAATAIIWSAVERLMSPAPLVQPGVGLALSTAAAGVNLVVGVTL LRMGRRHRSVTLVADGKHLMTDVWTSAGVIVGISLVALTDWYPLDPIVALAVGVNILWTGYRLLRGSMSS LLSAALPEQDHAAVNAVLDRYRSEYPIEFAPLRTVESGRQRLVFVVVTVPGEWTVQAAHDLADRLEEDID AALPHTETFIHVEPAGTSAR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5864 | - | - | 100% (300) | cation diffusion facilitator family transporter |
| M. vanbaalenii PYR-1 | Mvan_3225 | - | 7e-19 | 28.28% (290) | cation diffusion facilitator family transporter |
| M. vanbaalenii PYR-1 | Mvan_3726 | - | 9e-19 | 28.42% (285) | cation diffusion facilitator family transporter |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2050c | - | 2e-17 | 29.76% (289) | hypothetical protein Mb2050c |
| M. gilvum PYR-GCK | Mflv_1902 | - | 7e-18 | 29.56% (274) | cation diffusion facilitator family transporter |
| M. tuberculosis H37Rv | Rv2025c | - | 2e-17 | 29.76% (289) | hypothetical protein Rv2025c |
| M. leprae Br4923 | MLBr_00283 | - | 3e-12 | 25.61% (246) | putative cation-efflux transporter component |
| M. abscessus ATCC 19977 | MAB_0183c | - | 3e-18 | 25.83% (271) | putative cation transporter |
| M. marinum M | MMAR_2144 | - | 8e-20 | 27.34% (278) | hypothetical protein MMAR_2144 |
| M. avium 104 | MAV_3555 | - | 2e-15 | 27.27% (209) | cation efflux family protein |
| M. smegmatis MC2 155 | MSMEG_0755 | - | 9e-11 | 29.25% (212) | cobalt-zinc-cadmium resistance protein |
| M. thermoresistible (build 8) | TH_1241 | - | 1e-09 | 23.79% (206) | integral membrane protein |
| M. ulcerans Agy99 | MUL_1315 | - | 7e-15 | 26.20% (271) | hypothetical protein MUL_1315 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2050c|M.bovis_AF2122/97 MTHD---------------HAHS-RG--VPAMIKEIFAPHSHDAADSVDD
Rv2025c|M.tuberculosis_H37Rv MTHD---------------HAHS-RG--VPAMIKEIFAPHSHDAADSVDD
Mflv_1902|M.gilvum_PYR-GCK MTHDAHAHHDHGSGHDHHPHSHSGRGGKIGAALREVFAPHSHDASDSIDS
MAV_3555|M.avium_104 -----------------------------MHVINGVRDPAASFPLDTATD
MUL_1315|M.ulcerans_Agy99 --------------------------------------------------
MLBr_00283|M.leprae_Br4923 -----------------------------MQCMRKHAYIAHMGSGGSYTP
MSMEG_0755|M.smegmatis_MC2_155 -----------------------------------------MGAGHDHSH
MMAR_2144|M.marinum_M -----------------------------------MVAGHAHSAGAESLP
MAB_0183c|M.abscessus_ATCC_199 -----------------------------------MAADAHEHGSGHSHG
Mvan_5864|M.vanbaalenii_PYR-1 --------------------------------------------MTTPLS
TH_1241|M.thermoresistible__bu --------------------------------------VTPSGAIGWRPL
Mb2050c|M.bovis_AF2122/97 TLESTAAGIRTVKISLLVLGLTALIQIVIVVMSGSVALAADTIHNFADAL
Rv2025c|M.tuberculosis_H37Rv TLESTAAGIRTVKISLLVLGLTALIQIVIVVMSGSVALAADTIHNFADAL
Mflv_1902|M.gilvum_PYR-GCK ALESSAAGIRAVKISLLVLGVTAIAQIAIVAISGSVALLADTIHNFSDAL
MAV_3555|M.avium_104 DAGERRQANRAVAVSAAGLALTGLVELVIAVVSGSVALLGDALHNLSDVS
MUL_1315|M.ulcerans_Agy99 --------------------MTGLIELAIALVSGSVALLGDALHNLYDVS
MLBr_00283|M.leprae_Br4923 AEAAIYRMIRRMIVAAAILMVFFGVELTIALLINSITLLADAGHMLTDVV
MSMEG_0755|M.smegmatis_MC2_155 HTDAR---VSRMLVAAAILTAFFFVELITALMINSIALLADAGHMLTDLV
MMAR_2144|M.marinum_M TGSAGAAYKRRLALALTLTASYALVEVVGGILTGSLALISDAAHMGTDVL
MAB_0183c|M.abscessus_ATCC_199 HGVNADADRKWLTIALILIGGFMAIEVVIGIIAQSLALISDAGHMLTDAA
Mvan_5864|M.vanbaalenii_PYR-1 RQQEHRLLSRFMLLSLAAAIVTMALKAGAAVITGSVGFLSDALESGVNLV
TH_1241|M.thermoresistible__bu SESRRQQLARRIRVLVAATISYNIIEAVVAIGEGARVSSTALIGFGLDSA
: : :
Mb2050c|M.bovis_AF2122/97 TAVPLWIAFALGAKP-ATRRYTYGFGRVEDLAGSFVVAMITMSAIIAGYE
Rv2025c|M.tuberculosis_H37Rv TAVPLWIAFALGAKP-ATRRYTYGFGRVEDLAGSFVVAMITMSAIIAGYE
Mflv_1902|M.gilvum_PYR-GCK TAIPLWIAFALSTKA-ATRRYTYGFGRAEDLAGLFVVAMIALSAIIAGVE
MAV_3555|M.avium_104 TSALVFVGFRASRKL-PTERYPYGYERAEDLAGIGVALVIWGSAVVAGFE
MUL_1315|M.ulcerans_Agy99 TSLVVFVGFRSSRKS-ASERYPYGLERAEDLAGIGVALVIWASAAVAGTE
MLBr_00283|M.leprae_Br4923 AVFMGLAALVLAKHGHSAPNRPYSWHRAEVFTAMANAALLIGVATFILYE
MSMEG_0755|M.smegmatis_MC2_155 AMFMGLTAVLLARRGSTSPARTFGWHRAEVFTAVANAALLIGVAGFILYE
MMAR_2144|M.marinum_M GLGLALAAIHLANQP-AASQRTYGTYRLEVLAAVINGLLLFGVAGYVLYE
MAB_0183c|M.abscessus_ATCC_199 SIVLALIAIRLSSRP-ARGSYTFGLKRAEILSAQANGVTLFLLAAFFIYE
Mvan_5864|M.vanbaalenii_PYR-1 AAVVALWALRVAARP-RDADHHFGHGKAEYLSALVEGAMIFVAATAIIWS
TH_1241|M.thermoresistible__bu IEVSSAAAVAWQFAG-------RDPEARERIALRVIAFSFFGLATFVTVD
.. . * :: : * .
Mb2050c|M.bovis_AF2122/97 AIARLIHPQQIEHVGWVALAGLVGFIGNEWVALYRIRVGHRIGSAALIAD
Rv2025c|M.tuberculosis_H37Rv AIARLIHPQQIEHVGWVALAGLVGFIGNEWVALYRIRVGHRIGSAALIAD
Mflv_1902|M.gilvum_PYR-GCK SVRRLINPVPIEHVGWVALAGLVGFIGNELVALYRIRVGRRISSAALVAD
MAV_3555|M.avium_104 SVTKLLRHGGTGHVGWGIAAAVVGVVGNQLVARYKLVVGRRIRSATMVAD
MUL_1315|M.ulcerans_Agy99 SVGKLLRHGSTQHVGWGIAAAAVGIVGNQLVARYKLVVGRRIQSSTMIAD
MLBr_00283|M.leprae_Br4923 AIRRFKEAPYIPGMPIVVAALAGLVTN---FVVAPLLRPHAEDSLAIKGA
MSMEG_0755|M.smegmatis_MC2_155 AFERLGNAPEVPGVPMIVVALAGLIAN---AAVVLMLRSHSKDSLAVKGA
MMAR_2144|M.marinum_M AYQRIQEPPEILGVPMLVVAVAGLAVN---LVSFRMLSAGAKESLNVRGA
MAB_0183c|M.abscessus_ATCC_199 GIRRLITPPEVSGLLVFITALAGIAVN---VAATWCISKANRSSLNVEGA
Mvan_5864|M.vanbaalenii_PYR-1 AVERLMSPAPLVQPGVGLALSTAAAGVNLVVGVTLLRMGRRHRSVTLVAD
TH_1241|M.thermoresistible__bu AVRALLGMGESRPSTVGIVVAALSLLIMPVLSYAQRRAGRELGSLSAVAD
. : * .
Mb2050c|M.bovis_AF2122/97 GLHARTDGFTSLAVLCS-AGGVALGFPLADPIVGLLITAAILAVLRTAAR
Rv2025c|M.tuberculosis_H37Rv GLHARTDGFTSLAVLCS-AGGVALGFPLADPIVGLLITAAILAVLRTAAR
Mflv_1902|M.gilvum_PYR-GCK GLHARTDGFTSLAVLLG-AGGVALGFPLADPVIGLVITVAILAILRTAAR
MAV_3555|M.avium_104 AKHSWLDALSSAGAVLG-LIGVALGWGWADAVAGIVVTGFICHVGWEVTA
MUL_1315|M.ulcerans_Agy99 AKHSWLDALSSAGALLG-LCGVAMGWGWADGVAGLAVTGFICHVGWEVSS
MLBr_00283|M.leprae_Br4923 YMEAVADTVGNIGVLIAGVVTLTTHWPYADVVVAVLVALWVLPRAISLAR
MSMEG_0755|M.smegmatis_MC2_155 YMEVVADTVGSIGVLIAGIVTVTTGWPYADVVVAVLVALWVLPRAIALAR
MMAR_2144|M.marinum_M YLEVLSDMLGSIGVIVAAVVIATTGWRYADAIVGAGIGLFILPRTYSLMK
MAB_0183c|M.abscessus_ATCC_199 FQHILNDLYAFIATAVAGAVVWLTGFTRADAIAALVVAALMLKAGWGLVR
Mvan_5864|M.vanbaalenii_PYR-1 GKHLMTDVWTSAGVIVGISLVALTDWYPLDPIVALAVGVNILWTGYRLLR
TH_1241|M.thermoresistible__bu SKQTLLCTYLSAVLLIGLLLNSLFGWSWADPVAGLAIAAMAVREGIEAWR
. . : * : . :
Mb2050c|M.bovis_AF2122/97 DVFRRLLDGVDPAMVDAAEQALAARPGVQAVRSVRMRWIGHRLHADAELD
Rv2025c|M.tuberculosis_H37Rv DVFRRLLDGVDPAMVDAAEQALAARPGVQAVRSVRMRWIGHRLHADAELD
Mflv_1902|M.gilvum_PYR-GCK DIFRRLMDGVDPGFVASAESALAAEPGVLAVRSVRMRWVGHRLHADAELD
MAV_3555|M.avium_104 DIAHRLLDGVDPDIVTTAEAVAVSVPGVTHAH-ARARWTGRTLRVEVEGF
MUL_1315|M.ulcerans_Agy99 EIGHRLLDGVDPGVVDTAEAVAAAIPGVVHAH-ARARWTGRTLRVEVEGW
MLBr_00283|M.leprae_Br4923 AACGSFPNCRRPTIDVEALRSALGRRR---------------------RH
MSMEG_0755|M.smegmatis_MC2_155 AALRILSESSPAHIDVEKLRSALCAVDGVTDVHDLHVWTLVPGKDMVTAH
MMAR_2144|M.marinum_M QAVRIIMEVAPPEIDIAEVQGKLTAIAGVDSVHDLHIWTITSGMEAATVH
MAB_0183c|M.abscessus_ATCC_199 ESGRIFLEAAPVGLDPGTIGTQLAAVHAVAEVHDLHIWQITSGQPALSAH
Mvan_5864|M.vanbaalenii_PYR-1 GSMSSLLSAALPEQDHAAVNAVLDRYRSEYPIEFAPLRTVESGRQRLVFV
TH_1241|M.thermoresistible__bu GDTCCAVPVGTSRTATESGCGCGDDRE-----------------------
Mb2050c|M.bovis_AF2122/97 VDPAL---DLAQAHRIAHDAEHELTHTVPKLTTALIHAYPAEHGSSIPDR
Rv2025c|M.tuberculosis_H37Rv VDPAL---DLAQAHRIAHDAEHELTHTVPKLTTALIHAYPAEHGSSIPDR
Mflv_1902|M.gilvum_PYR-GCK IDPAV---SLADAHRIAHEAEHTLTHAVPKLASALVHAYPDSGGSSH---
MAV_3555|M.avium_104 LDAAT---SLSDSDRIGRSVAAALAPRLPQMQSFTWTARAA---------
MUL_1315|M.ulcerans_Agy99 ADPAM---SVADADDIGRRVADQLGARLPQMRSFSWAARGVPLG------
MLBr_00283|M.leprae_Br4923 RS--------ARPARVNTFARR-------------RYVPPRT--------
MSMEG_0755|M.smegmatis_MC2_155 LTS------DADTARVLDDARAVLT-AHGLEHATVQVEPPDAAGDCRCEA
MMAR_2144|M.marinum_M LVVPR----SLDWHRVLDTARDILA-DYGVTHPTIQVEPVDHVERGSLV-
MAB_0183c|M.abscessus_ATCC_199 ILVAP----NADCHGIRREIEELLHTQYDIDHTTLQVDHEGTEASTHCFD
Mvan_5864|M.vanbaalenii_PYR-1 VVTVPGEWTVQAAHDLADRLEEDIDAALPHTETFIHVEPAGTSAR-----
TH_1241|M.thermoresistible__bu --------------------------------------------------
Mb2050c|M.bovis_AF2122/97 GRTVE------------
Rv2025c|M.tuberculosis_H37Rv GRTVE------------
Mflv_1902|M.gilvum_PYR-GCK -----------------
MAV_3555|M.avium_104 -----------------
MUL_1315|M.ulcerans_Agy99 -----------------
MLBr_00283|M.leprae_Br4923 -----------------
MSMEG_0755|M.smegmatis_MC2_155 E----------------
MMAR_2144|M.marinum_M -----------------
MAB_0183c|M.abscessus_ATCC_199 PHGEPYRADGSALPGKG
Mvan_5864|M.vanbaalenii_PYR-1 -----------------
TH_1241|M.thermoresistible__bu -----------------