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AHEPIAATDPHEGNSHADNDGHDQGSHDHGEGHSHDHDHGHGHSHDGWGGKFGAAIREVFAPHSHDASDS IDGALESSAAGIRAVKISLLALGVTAIAQIVIVVISSSVALLADTIHNFSDALTAVPLWIAFALSTKAAT RRYTYGFGRAEDLAGLFVVAMITLSAIIAGIESIRRLINPVPIEHVGWVAAAGLVGFIGNELVAVYRIRV GRQIGSAALIADGLHARTDGFTSLAVLFGAGGVALGFPLADPIIGLVITVAILAVLRTAVRDIFRRLMDA VDPKFVDTAEAALAAEPGVTGVRSVKMRWMGHRLHADAELDIDPATSLSEAHRIAHDAEHTLTHAVPKLS SALVHAYPAGGSTEPEDHRHDVEPSHPHQQ*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3726 | - | - | 100% (381) | cation diffusion facilitator family transporter |
| M. vanbaalenii PYR-1 | Mvan_3225 | - | e-158 | 79.65% (344) | cation diffusion facilitator family transporter |
| M. vanbaalenii PYR-1 | Mvan_5864 | - | 1e-18 | 28.42% (285) | cation diffusion facilitator family transporter |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2050c | - | 1e-140 | 74.12% (340) | hypothetical protein Mb2050c |
| M. gilvum PYR-GCK | Mflv_1902 | - | 1e-163 | 85.17% (344) | cation diffusion facilitator family transporter |
| M. tuberculosis H37Rv | Rv2025c | - | 1e-140 | 74.12% (340) | hypothetical protein Rv2025c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0183c | - | 5e-14 | 26.24% (362) | putative cation transporter |
| M. marinum M | MMAR_3313 | - | 5e-54 | 40.97% (288) | hypothetical protein MMAR_3313 |
| M. avium 104 | MAV_3555 | - | 3e-56 | 43.12% (269) | cation efflux family protein |
| M. smegmatis MC2 155 | MSMEG_0755 | - | 2e-09 | 25.08% (295) | cobalt-zinc-cadmium resistance protein |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_1315 | - | 5e-50 | 41.47% (258) | hypothetical protein MUL_1315 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_3726|M.vanbaalenii_PYR-1 MAHEPIAATDPHEGNSHADNDGHDQGSHDHGEGHSHDHDHGHGHSHDGWG
Mflv_1902|M.gilvum_PYR-GCK MTHD-----------AHAH--------HDHGSGHDH-----HPHSHSGRG
Mb2050c|M.bovis_AF2122/97 MTHD-------------------------------------HAHSRG---
Rv2025c|M.tuberculosis_H37Rv MTHD-------------------------------------HAHSRG---
MMAR_3313|M.marinum_M --------------------------------------------------
MUL_1315|M.ulcerans_Agy99 --------------------------------------------------
MAV_3555|M.avium_104 --------------------------------------------------
MAB_0183c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_0755|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_3726|M.vanbaalenii_PYR-1 GKFGAAIREVFAPHSHDASDSIDGALESSAAGIRAVKISLLALGVTAIAQ
Mflv_1902|M.gilvum_PYR-GCK GKIGAALREVFAPHSHDASDSIDSALESSAAGIRAVKISLLVLGVTAIAQ
Mb2050c|M.bovis_AF2122/97 --VPAMIKEIFAPHSHDAADSVDDTLESTAAGIRTVKISLLVLGLTALIQ
Rv2025c|M.tuberculosis_H37Rv --VPAMIKEIFAPHSHDAADSVDDTLESTAAGIRTVKISLLVLGLTALIQ
MMAR_3313|M.marinum_M --MHLVDGQRDPAASFPLAQAVDDQAERRRA-NRAVAVSAAGLGLTGLIE
MUL_1315|M.ulcerans_Agy99 --------------------------------------------MTGLIE
MAV_3555|M.avium_104 --MHVINGVRDPAASFPLDTATDDAGERRQA-NRAVAVSAAGLALTGLVE
MAB_0183c|M.abscessus_ATCC_199 ---------MAADAHEHGSGHSHGHGVNADADRKWLTIALILIGGFMAIE
MSMEG_0755|M.smegmatis_MC2_155 ----------------MGAGHDHSHHTDARVSR--MLVAAAILTAFFFVE
:
Mvan_3726|M.vanbaalenii_PYR-1 IVIVVISSSVALLADTIHNFSDALTAVPLWIAFALSTKAATR-RYTYGFG
Mflv_1902|M.gilvum_PYR-GCK IAIVAISGSVALLADTIHNFSDALTAIPLWIAFALSTKAATR-RYTYGFG
Mb2050c|M.bovis_AF2122/97 IVIVVMSGSVALAADTIHNFADALTAVPLWIAFALGAKPATR-RYTYGFG
Rv2025c|M.tuberculosis_H37Rv IVIVVMSGSVALAADTIHNFADALTAVPLWIAFALGAKPATR-RYTYGFG
MMAR_3313|M.marinum_M LAIALVSGSVALLGDALHNLSDVSTSLVVFVGFRSSRKSASE-RYPYGLE
MUL_1315|M.ulcerans_Agy99 LAIALVSGSVALLGDALHNLYDVSTSLVVFVGFRSSRKSASE-RYPYGLE
MAV_3555|M.avium_104 LVIAVVSGSVALLGDALHNLSDVSTSALVFVGFRASRKLPTE-RYPYGYE
MAB_0183c|M.abscessus_ATCC_199 VVIGIIAQSLALISDAGHMLTDAASIVLALIAIRLSSRPARG-SYTFGLK
MSMEG_0755|M.smegmatis_MC2_155 LITALMINSIALLADAGHMLTDLVAMFMGLTAVLLARRGSTSPARTFGWH
: : *:** .*: * : * : .. . : . .:*
Mvan_3726|M.vanbaalenii_PYR-1 RAEDLAGLFVVAMITLSAIIAGIESIRRLINPVPIEHVGWVAAAGLVGFI
Mflv_1902|M.gilvum_PYR-GCK RAEDLAGLFVVAMIALSAIIAGVESVRRLINPVPIEHVGWVALAGLVGFI
Mb2050c|M.bovis_AF2122/97 RVEDLAGSFVVAMITMSAIIAGYEAIARLIHPQQIEHVGWVALAGLVGFI
Rv2025c|M.tuberculosis_H37Rv RVEDLAGSFVVAMITMSAIIAGYEAIARLIHPQQIEHVGWVALAGLVGFI
MMAR_3313|M.marinum_M RAEDLAGIGVALVIWASAAVAGTESVGKLLRHGSTQHVGWGIAAAAVGIV
MUL_1315|M.ulcerans_Agy99 RAEDLAGIGVALVIWASAAVAGTESVGKLLRHGSTQHVGWGIAAAAVGIV
MAV_3555|M.avium_104 RAEDLAGIGVALVIWGSAVVAGFESVTKLLRHGGTGHVGWGIAAAVVGVV
MAB_0183c|M.abscessus_ATCC_199 RAEILSAQANGVTLFLLAAFFIYEGIRRLITPPEVSGL-LVFITALAGIA
MSMEG_0755|M.smegmatis_MC2_155 RAEVFTAVANAALLIGVAGFILYEAFERLGNAPEVPGV-PMIVVALAGLI
*.* ::. : * . *.. :* : .. .*.
Mvan_3726|M.vanbaalenii_PYR-1 GNELVAVYRIRVGRQIGSAALIADGLHARTDGFTSLAVLFG-AGGVALGF
Mflv_1902|M.gilvum_PYR-GCK GNELVALYRIRVGRRISSAALVADGLHARTDGFTSLAVLLG-AGGVALGF
Mb2050c|M.bovis_AF2122/97 GNEWVALYRIRVGHRIGSAALIADGLHARTDGFTSLAVLCS-AGGVALGF
Rv2025c|M.tuberculosis_H37Rv GNEWVALYRIRVGHRIGSAALIADGLHARTDGFTSLAVLCS-AGGVALGF
MMAR_3313|M.marinum_M GNQLVARYKLVVGRRIQSSTMIADAKHSWLDALSSAGALLG-LCGVAKGW
MUL_1315|M.ulcerans_Agy99 GNQLVARYKLVVGRRIQSSTMIADAKHSWLDALSSAGALLG-LCGVAMGW
MAV_3555|M.avium_104 GNQLVARYKLVVGRRIRSATMVADAKHSWLDALSSAGAVLG-LIGVALGW
MAB_0183c|M.abscessus_ATCC_199 VNVAATWCISKANR--SSLNVEGAFQHILNDLYAFIATAVAGAVVWLTGF
MSMEG_0755|M.smegmatis_MC2_155 ANAAVVLMLRSHSK--DSLAVKGAYMEVVADTVGSIGVLIAGIVTVTTGW
* .. .: * : . . * .. . *:
Mvan_3726|M.vanbaalenii_PYR-1 PLADPIIGLVITVAILAVLRTAVRDIFRRLMDA----VDPKFVDTAEAAL
Mflv_1902|M.gilvum_PYR-GCK PLADPVIGLVITVAILAILRTAARDIFRRLMDG----VDPGFVASAESAL
Mb2050c|M.bovis_AF2122/97 PLADPIVGLLITAAILAVLRTAARDVFRRLLDG----VDPAMVDAAEQAL
Rv2025c|M.tuberculosis_H37Rv PLADPIVGLLITAAILAVLRTAARDVFRRLLDG----VDPAMVDAAEQAL
MMAR_3313|M.marinum_M GWADGVAGLAVTGFICHVGWEVSSEIGHRLLDG----VDPGVVDTAEAVA
MUL_1315|M.ulcerans_Agy99 GWADGVAGLAVTGFICHVGWEVSSEIGHRLLDG----VDPGVVDTAEAVA
MAV_3555|M.avium_104 GWADAVAGIVVTGFICHVGWEVTADIAHRLLDG----VDPDIVTTAEAVA
MAB_0183c|M.abscessus_ATCC_199 TRADAIAALVVAALMLKAGWGLVRESGRIFLEAAPVGLDPGTIGTQLAAV
MSMEG_0755|M.smegmatis_MC2_155 PYADVVVAVLVALWVLPRAIALARAALRILSESSPAHIDVEKLRSALCAV
** : .: :: : : : :. :* : : .
Mvan_3726|M.vanbaalenii_PYR-1 AAEPGVTGVRSVKMRWMGHRLHADAELDIDPATS-LSEAHRIAHDAEHTL
Mflv_1902|M.gilvum_PYR-GCK AAEPGVLAVRSVRMRWVGHRLHADAELDIDPAVS-LADAHRIAHEAEHTL
Mb2050c|M.bovis_AF2122/97 AARPGVQAVRSVRMRWIGHRLHADAELDVDPALD-LAQAHRIAHDAEHEL
Rv2025c|M.tuberculosis_H37Rv AARPGVQAVRSVRMRWIGHRLHADAELDVDPALD-LAQAHRIAHDAEHEL
MMAR_3313|M.marinum_M AAIPGVVHAH-ARARWTGRTLRVEVEGWVDPAMS-VADADDIGRRVADQL
MUL_1315|M.ulcerans_Agy99 AAIPGVVHAH-ARARWTGRTLRVEVEGWADPAMS-VADADDIGRRVADQL
MAV_3555|M.avium_104 VSVPGVTHAH-ARARWTGRTLRVEVEGFLDAATS-LSDSDRIGRSVAAAL
MAB_0183c|M.abscessus_ATCC_199 HAVAEVHDLHIWQITSGQPALSAHILVAPNADCHGIRREIEELLHTQYDI
MSMEG_0755|M.smegmatis_MC2_155 DGVTDVHDLHVWTLVPGKDMVTAHLTSDADTAR---VLDDARAVLTAHGL
. . * : : .. :. . :
Mvan_3726|M.vanbaalenii_PYR-1 THAVPKLSSALVHAYPAGGSTEPEDHRHDVEPSHPHQQ----
Mflv_1902|M.gilvum_PYR-GCK THAVPKLASALVHAYPDSGGS-----------SH--------
Mb2050c|M.bovis_AF2122/97 THTVPKLTTALIHAYPAEHGS-----------SIPDRGRTVE
Rv2025c|M.tuberculosis_H37Rv THTVPKLTTALIHAYPAEHGS-----------SIPDRGRTVE
MMAR_3313|M.marinum_M GARLPQMRSFSWAARGVPLG----------------------
MUL_1315|M.ulcerans_Agy99 GARLPQMRSFSWAARGVPLG----------------------
MAV_3555|M.avium_104 APRLPQMQSFTWTARAA-------------------------
MAB_0183c|M.abscessus_ATCC_199 DHTTLQVDHEGTEASTHCFDPHGEPYRADGSALPGKG-----
MSMEG_0755|M.smegmatis_MC2_155 EHATVQVEPPDAAGDCRCEAE---------------------
:: .