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MTHDAHAHHDHGSGHDHHPHSHSGRGGKIGAALREVFAPHSHDASDSIDSALESSAAGIRAVKISLLVLG VTAIAQIAIVAISGSVALLADTIHNFSDALTAIPLWIAFALSTKAATRRYTYGFGRAEDLAGLFVVAMIA LSAIIAGVESVRRLINPVPIEHVGWVALAGLVGFIGNELVALYRIRVGRRISSAALVADGLHARTDGFTS LAVLLGAGGVALGFPLADPVIGLVITVAILAILRTAARDIFRRLMDGVDPGFVASAESALAAEPGVLAVR SVRMRWVGHRLHADAELDIDPAVSLADAHRIAHEAEHTLTHAVPKLASALVHAYPDSGGSSH
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1902 | - | - | 100% (342) | cation diffusion facilitator family transporter |
| M. gilvum PYR-GCK | Mflv_0231 | - | 4e-08 | 25.87% (259) | cation diffusion facilitator family transporter |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2050c | - | 1e-142 | 77.16% (324) | hypothetical protein Mb2050c |
| M. tuberculosis H37Rv | Rv2025c | - | 1e-142 | 77.16% (324) | hypothetical protein Rv2025c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0183c | - | 3e-14 | 26.01% (323) | putative cation transporter |
| M. marinum M | MMAR_3313 | - | 1e-57 | 42.71% (288) | hypothetical protein MMAR_3313 |
| M. avium 104 | MAV_3555 | - | 2e-55 | 41.67% (288) | cation efflux family protein |
| M. smegmatis MC2 155 | MSMEG_0755 | - | 9e-10 | 26.73% (303) | cobalt-zinc-cadmium resistance protein |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_1315 | - | 7e-54 | 43.41% (258) | hypothetical protein MUL_1315 |
| M. vanbaalenii PYR-1 | Mvan_3726 | - | 1e-163 | 85.17% (344) | cation diffusion facilitator family transporter |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2050c|M.bovis_AF2122/97 MTHD-------------------------------------HAHSRG---
Rv2025c|M.tuberculosis_H37Rv MTHD-------------------------------------HAHSRG---
Mflv_1902|M.gilvum_PYR-GCK MTHD-----------AHAH--------HDHGSGHDH-----HPHSHSGRG
Mvan_3726|M.vanbaalenii_PYR-1 MAHEPIAATDPHEGNSHADNDGHDQGSHDHGEGHSHDHDHGHGHSHDGWG
MMAR_3313|M.marinum_M --------------------------------------------------
MUL_1315|M.ulcerans_Agy99 --------------------------------------------------
MAV_3555|M.avium_104 --------------------------------------------------
MAB_0183c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_0755|M.smegmatis_MC2_155 --------------------------------------------------
Mb2050c|M.bovis_AF2122/97 --VPAMIKEIFAPHSHDAADSVDDTLESTAAGIRTVKISLLVLGLTALIQ
Rv2025c|M.tuberculosis_H37Rv --VPAMIKEIFAPHSHDAADSVDDTLESTAAGIRTVKISLLVLGLTALIQ
Mflv_1902|M.gilvum_PYR-GCK GKIGAALREVFAPHSHDASDSIDSALESSAAGIRAVKISLLVLGVTAIAQ
Mvan_3726|M.vanbaalenii_PYR-1 GKFGAAIREVFAPHSHDASDSIDGALESSAAGIRAVKISLLALGVTAIAQ
MMAR_3313|M.marinum_M --MHLVDGQRDPAASFPLAQAVDDQAERRRA-NRAVAVSAAGLGLTGLIE
MUL_1315|M.ulcerans_Agy99 --------------------------------------------MTGLIE
MAV_3555|M.avium_104 --MHVINGVRDPAASFPLDTATDDAGERRQA-NRAVAVSAAGLALTGLVE
MAB_0183c|M.abscessus_ATCC_199 ---------MAADAHEHGSGHSHGHGVNADADRKWLTIALILIGGFMAIE
MSMEG_0755|M.smegmatis_MC2_155 ----------------MGAGHDHSHHTDARVSR--MLVAAAILTAFFFVE
:
Mb2050c|M.bovis_AF2122/97 IVIVVMSGSVALAADTIHNFADALTAVPLWIAFALGAKPATR-RYTYGFG
Rv2025c|M.tuberculosis_H37Rv IVIVVMSGSVALAADTIHNFADALTAVPLWIAFALGAKPATR-RYTYGFG
Mflv_1902|M.gilvum_PYR-GCK IAIVAISGSVALLADTIHNFSDALTAIPLWIAFALSTKAATR-RYTYGFG
Mvan_3726|M.vanbaalenii_PYR-1 IVIVVISSSVALLADTIHNFSDALTAVPLWIAFALSTKAATR-RYTYGFG
MMAR_3313|M.marinum_M LAIALVSGSVALLGDALHNLSDVSTSLVVFVGFRSSRKSASE-RYPYGLE
MUL_1315|M.ulcerans_Agy99 LAIALVSGSVALLGDALHNLYDVSTSLVVFVGFRSSRKSASE-RYPYGLE
MAV_3555|M.avium_104 LVIAVVSGSVALLGDALHNLSDVSTSALVFVGFRASRKLPTE-RYPYGYE
MAB_0183c|M.abscessus_ATCC_199 VVIGIIAQSLALISDAGHMLTDAASIVLALIAIRLSSRPARG-SYTFGLK
MSMEG_0755|M.smegmatis_MC2_155 LITALMINSIALLADAGHMLTDLVAMFMGLTAVLLARRGSTSPARTFGWH
: : *:** .*: * : * : .. . : . .:*
Mb2050c|M.bovis_AF2122/97 RVEDLAGSFVVAMITMSAIIAGYEAIARLIHPQQIEHVGWVALAGLVGFI
Rv2025c|M.tuberculosis_H37Rv RVEDLAGSFVVAMITMSAIIAGYEAIARLIHPQQIEHVGWVALAGLVGFI
Mflv_1902|M.gilvum_PYR-GCK RAEDLAGLFVVAMIALSAIIAGVESVRRLINPVPIEHVGWVALAGLVGFI
Mvan_3726|M.vanbaalenii_PYR-1 RAEDLAGLFVVAMITLSAIIAGIESIRRLINPVPIEHVGWVAAAGLVGFI
MMAR_3313|M.marinum_M RAEDLAGIGVALVIWASAAVAGTESVGKLLRHGSTQHVGWGIAAAAVGIV
MUL_1315|M.ulcerans_Agy99 RAEDLAGIGVALVIWASAAVAGTESVGKLLRHGSTQHVGWGIAAAAVGIV
MAV_3555|M.avium_104 RAEDLAGIGVALVIWGSAVVAGFESVTKLLRHGGTGHVGWGIAAAVVGVV
MAB_0183c|M.abscessus_ATCC_199 RAEILSAQANGVTLFLLAAFFIYEGIRRLITPPEVSGL-LVFITALAGIA
MSMEG_0755|M.smegmatis_MC2_155 RAEVFTAVANAALLIGVAGFILYEAFERLGNAPEVPGV-PMIVVALAGLI
*.* ::. : * . *.. :* : .. .*.
Mb2050c|M.bovis_AF2122/97 GNEWVALYRIRVGHRIGSAALIADGLHARTDGFTSLAVLCS-AGGVALGF
Rv2025c|M.tuberculosis_H37Rv GNEWVALYRIRVGHRIGSAALIADGLHARTDGFTSLAVLCS-AGGVALGF
Mflv_1902|M.gilvum_PYR-GCK GNELVALYRIRVGRRISSAALVADGLHARTDGFTSLAVLLG-AGGVALGF
Mvan_3726|M.vanbaalenii_PYR-1 GNELVAVYRIRVGRQIGSAALIADGLHARTDGFTSLAVLFG-AGGVALGF
MMAR_3313|M.marinum_M GNQLVARYKLVVGRRIQSSTMIADAKHSWLDALSSAGALLG-LCGVAKGW
MUL_1315|M.ulcerans_Agy99 GNQLVARYKLVVGRRIQSSTMIADAKHSWLDALSSAGALLG-LCGVAMGW
MAV_3555|M.avium_104 GNQLVARYKLVVGRRIRSATMVADAKHSWLDALSSAGAVLG-LIGVALGW
MAB_0183c|M.abscessus_ATCC_199 VNVAATWCISKANR--SSLNVEGAFQHILNDLYAFIATAVAGAVVWLTGF
MSMEG_0755|M.smegmatis_MC2_155 ANAAVVLMLRSHSK--DSLAVKGAYMEVVADTVGSIGVLIAGIVTVTTGW
* .. .: * : . . * .. . *:
Mb2050c|M.bovis_AF2122/97 PLADPIVGLLITAAILAVLRTAARDVFRRLLDG----VDPAMVDAAEQAL
Rv2025c|M.tuberculosis_H37Rv PLADPIVGLLITAAILAVLRTAARDVFRRLLDG----VDPAMVDAAEQAL
Mflv_1902|M.gilvum_PYR-GCK PLADPVIGLVITVAILAILRTAARDIFRRLMDG----VDPGFVASAESAL
Mvan_3726|M.vanbaalenii_PYR-1 PLADPIIGLVITVAILAVLRTAVRDIFRRLMDA----VDPKFVDTAEAAL
MMAR_3313|M.marinum_M GWADGVAGLAVTGFICHVGWEVSSEIGHRLLDG----VDPGVVDTAEAVA
MUL_1315|M.ulcerans_Agy99 GWADGVAGLAVTGFICHVGWEVSSEIGHRLLDG----VDPGVVDTAEAVA
MAV_3555|M.avium_104 GWADAVAGIVVTGFICHVGWEVTADIAHRLLDG----VDPDIVTTAEAVA
MAB_0183c|M.abscessus_ATCC_199 TRADAIAALVVAALMLKAGWGLVRESGRIFLEAAPVGLDPGTIGTQLAAV
MSMEG_0755|M.smegmatis_MC2_155 PYADVVVAVLVALWVLPRAIALARAALRILSESSPAHIDVEKLRSALCAV
** : .: :: : : : :. :* : : .
Mb2050c|M.bovis_AF2122/97 AARPGVQAVRSVRMRWIGHRLHADAELDVDPALD-----LAQAHRIAHDA
Rv2025c|M.tuberculosis_H37Rv AARPGVQAVRSVRMRWIGHRLHADAELDVDPALD-----LAQAHRIAHDA
Mflv_1902|M.gilvum_PYR-GCK AAEPGVLAVRSVRMRWVGHRLHADAELDIDPAVS-----LADAHRIAHEA
Mvan_3726|M.vanbaalenii_PYR-1 AAEPGVTGVRSVKMRWMGHRLHADAELDIDPATS-----LSEAHRIAHDA
MMAR_3313|M.marinum_M AAIPGVVHAH-ARARWTGRTLRVEVEGWVDPAMS-----VADADDIGRRV
MUL_1315|M.ulcerans_Agy99 AAIPGVVHAH-ARARWTGRTLRVEVEGWADPAMS-----VADADDIGRRV
MAV_3555|M.avium_104 VSVPGVTHAH-ARARWTGRTLRVEVEGFLDAATS-----LSDSDRIGRSV
MAB_0183c|M.abscessus_ATCC_199 HAVAEVHDLHIWQITSGQPALSAHILVAPNADCHGIRREIEELLHTQYDI
MSMEG_0755|M.smegmatis_MC2_155 DGVTDVHDLHVWTLVPGKDMVTAHLTSDADTAR---VLDDARAVLTAHGL
. . * : : .. :.
Mb2050c|M.bovis_AF2122/97 EHELTHTVPKLTTALIHAYPAEHGSSIPDRGRTVE-------
Rv2025c|M.tuberculosis_H37Rv EHELTHTVPKLTTALIHAYPAEHGSSIPDRGRTVE-------
Mflv_1902|M.gilvum_PYR-GCK EHTLTHAVPKLASALVHAYPDSGGS-----------SH----
Mvan_3726|M.vanbaalenii_PYR-1 EHTLTHAVPKLSSALVHAYPAGGSTEPEDHRHDVEPSHPHQQ
MMAR_3313|M.marinum_M ADQLGARLPQMRSFSWAARGVPLG------------------
MUL_1315|M.ulcerans_Agy99 ADQLGARLPQMRSFSWAARGVPLG------------------
MAV_3555|M.avium_104 AAALAPRLPQMQSFTWTARAA---------------------
MAB_0183c|M.abscessus_ATCC_199 DHTTLQVDHEGTEASTHCFDPHGEPYRADGSALPGKG-----
MSMEG_0755|M.smegmatis_MC2_155 EHATVQVEPPDAAGDCRCEAE---------------------
.