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MHVINGVRDPAASFPLDTATDDAGERRQANRAVAVSAAGLALTGLVELVIAVVSGSVALLGDALHNLSDV STSALVFVGFRASRKLPTERYPYGYERAEDLAGIGVALVIWGSAVVAGFESVTKLLRHGGTGHVGWGIAA AVVGVVGNQLVARYKLVVGRRIRSATMVADAKHSWLDALSSAGAVLGLIGVALGWGWADAVAGIVVTGFI CHVGWEVTADIAHRLLDGVDPDIVTTAEAVAVSVPGVTHAHARARWTGRTLRVEVEGFLDAATSLSDSDR IGRSVAAALAPRLPQMQSFTWTARAA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_3555 | - | - | 100% (306) | cation efflux family protein |
| M. avium 104 | MAV_4782 | - | 6e-13 | 28.72% (282) | cobalt-zinc-cadmium resistance protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2050c | - | 7e-50 | 38.57% (280) | hypothetical protein Mb2050c |
| M. gilvum PYR-GCK | Mflv_1902 | - | 2e-55 | 41.67% (288) | cation diffusion facilitator family transporter |
| M. tuberculosis H37Rv | Rv2025c | - | 7e-50 | 38.57% (280) | hypothetical protein Rv2025c |
| M. leprae Br4923 | MLBr_00283 | - | 6e-08 | 28.80% (184) | putative cation-efflux transporter component |
| M. abscessus ATCC 19977 | MAB_0183c | - | 2e-12 | 25.47% (212) | putative cation transporter |
| M. marinum M | MMAR_3313 | - | 1e-137 | 78.62% (304) | hypothetical protein MMAR_3313 |
| M. smegmatis MC2 155 | MSMEG_5604 | - | 1e-12 | 28.78% (205) | integral membrane protein |
| M. thermoresistible (build 8) | TH_1241 | - | 2e-11 | 29.08% (196) | integral membrane protein |
| M. ulcerans Agy99 | MUL_1315 | - | 1e-119 | 79.09% (263) | hypothetical protein MUL_1315 |
| M. vanbaalenii PYR-1 | Mvan_3726 | - | 3e-56 | 43.12% (269) | cation diffusion facilitator family transporter |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3313|M.marinum_M --------------------------------------------------
MUL_1315|M.ulcerans_Agy99 --------------------------------------------------
MAV_3555|M.avium_104 --------------------------------------------------
Mb2050c|M.bovis_AF2122/97 MTHD-------------------------------------HAHSRG---
Rv2025c|M.tuberculosis_H37Rv MTHD-------------------------------------HAHSRG---
Mflv_1902|M.gilvum_PYR-GCK MTHD-----------AHAH--------HDHGSGHDH-----HPHSHSGRG
Mvan_3726|M.vanbaalenii_PYR-1 MAHEPIAATDPHEGNSHADNDGHDQGSHDHGEGHSHDHDHGHGHSHDGWG
MSMEG_5604|M.smegmatis_MC2_155 ------------------------------------------------MR
TH_1241|M.thermoresistible__bu --------------------------------------------------
MLBr_00283|M.leprae_Br4923 --------------------------------------------------
MAB_0183c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_3313|M.marinum_M --MHLVDGQRDPAASFPLAQAVDDQAERRRA-NRAVAVSAAGLGLTGLIE
MUL_1315|M.ulcerans_Agy99 --------------------------------------------MTGLIE
MAV_3555|M.avium_104 --MHVINGVRDPAASFPLDTATDDAGERRQA-NRAVAVSAAGLALTGLVE
Mb2050c|M.bovis_AF2122/97 --VPAMIKEIFAPHSHDAADSVDDTLESTAAGIRTVKISLLVLGLTALIQ
Rv2025c|M.tuberculosis_H37Rv --VPAMIKEIFAPHSHDAADSVDDTLESTAAGIRTVKISLLVLGLTALIQ
Mflv_1902|M.gilvum_PYR-GCK GKIGAALREVFAPHSHDASDSIDSALESSAAGIRAVKISLLVLGVTAIAQ
Mvan_3726|M.vanbaalenii_PYR-1 GKFGAAIREVFAPHSHDASDSIDGALESSAAGIRAVKISLLALGVTAIAQ
MSMEG_5604|M.smegmatis_MC2_155 RPRWRRVRMRMMADTSKLTPTRRAVLARRIRMFVAATITYN--VIEAVVA
TH_1241|M.thermoresistible__bu ------VTPSGAIGWRPLSESRRQQLARRIRVLVAATISYN--IIEAVVA
MLBr_00283|M.leprae_Br4923 ---MQCMRKHAYIAHMGSGGSYTPAEAAIYRMIRRMIVAAAILMVFFGVE
MAB_0183c|M.abscessus_ATCC_199 ---------MAADAHEHGSGHSHGHGVNADADRKWLTIALILIGGFMAIE
MMAR_3313|M.marinum_M LAIALVSGSVALLGDALHNLSDVSTSLVVFVGFRSSRKSASE-RYPYGLE
MUL_1315|M.ulcerans_Agy99 LAIALVSGSVALLGDALHNLYDVSTSLVVFVGFRSSRKSASE-RYPYGLE
MAV_3555|M.avium_104 LVIAVVSGSVALLGDALHNLSDVSTSALVFVGFRASRKLPTE-RYPYGYE
Mb2050c|M.bovis_AF2122/97 IVIVVMSGSVALAADTIHNFADALTAVPLWIAFALGAKPATR-RYTYGFG
Rv2025c|M.tuberculosis_H37Rv IVIVVMSGSVALAADTIHNFADALTAVPLWIAFALGAKPATR-RYTYGFG
Mflv_1902|M.gilvum_PYR-GCK IAIVAISGSVALLADTIHNFSDALTAIPLWIAFALSTKAATR-RYTYGFG
Mvan_3726|M.vanbaalenii_PYR-1 IVIVVISSSVALLADTIHNFSDALTAVPLWIAFALSTKAATR-RYTYGFG
MSMEG_5604|M.smegmatis_MC2_155 LTEGARVSSTALIGFGLDSVIEVSSAAAVAWQFAGRDP-----------E
TH_1241|M.thermoresistible__bu IGEGARVSSTALIGFGLDSAIEVSSAAAVAWQFAGRDP-----------E
MLBr_00283|M.leprae_Br4923 LTIALLINSITLLADAGHMLTDVVAVFMGLAALVLAKHGHSAPNRPYSWH
MAB_0183c|M.abscessus_ATCC_199 VVIGIIAQSLALISDAGHMLTDAASIVLALIAIRLSSRPARG-SYTFGLK
: * :* . . :. : :
MMAR_3313|M.marinum_M RAEDLAGIGVALVIWASAAVAGTESVGKLLRHGSTQHVGWGIAAAAVGIV
MUL_1315|M.ulcerans_Agy99 RAEDLAGIGVALVIWASAAVAGTESVGKLLRHGSTQHVGWGIAAAAVGIV
MAV_3555|M.avium_104 RAEDLAGIGVALVIWGSAVVAGFESVTKLLRHGGTGHVGWGIAAAVVGVV
Mb2050c|M.bovis_AF2122/97 RVEDLAGSFVVAMITMSAIIAGYEAIARLIHPQQIEHVGWVALAGLVGFI
Rv2025c|M.tuberculosis_H37Rv RVEDLAGSFVVAMITMSAIIAGYEAIARLIHPQQIEHVGWVALAGLVGFI
Mflv_1902|M.gilvum_PYR-GCK RAEDLAGLFVVAMIALSAIIAGVESVRRLINPVPIEHVGWVALAGLVGFI
Mvan_3726|M.vanbaalenii_PYR-1 RAEDLAGLFVVAMITLSAIIAGIESIRRLINPVPIEHVGWVAAAGLVGFI
MSMEG_5604|M.smegmatis_MC2_155 AREKVALRIVAFSFFGLATYVAVDAIRSLLGIGEAQHSTIGIALAALSLV
TH_1241|M.thermoresistible__bu ARERIALRVIAFSFFGLATFVTVDAVRALLGMGESRPSTVGIVVAALSLL
MLBr_00283|M.leprae_Br4923 RAEVFTAMANAALLIGVATFILYEAIRRFKEAPYIP--GMPIVVAALAGL
MAB_0183c|M.abscessus_ATCC_199 RAEILSAQANGVTLFLLAAFFIYEGIRRLITPPEVS--GLLVFITALAGI
* .: : * :.: : :. :
MMAR_3313|M.marinum_M GNQLVARYKLVVGRRIQSSTMIADAKHSWLDALSSAGALLGLCG-VAKGW
MUL_1315|M.ulcerans_Agy99 GNQLVARYKLVVGRRIQSSTMIADAKHSWLDALSSAGALLGLCG-VAMGW
MAV_3555|M.avium_104 GNQLVARYKLVVGRRIRSATMVADAKHSWLDALSSAGAVLGLIG-VALGW
Mb2050c|M.bovis_AF2122/97 GNEWVALYRIRVGHRIGSAALIADGLHARTDGFTSLAVLCSAGG-VALGF
Rv2025c|M.tuberculosis_H37Rv GNEWVALYRIRVGHRIGSAALIADGLHARTDGFTSLAVLCSAGG-VALGF
Mflv_1902|M.gilvum_PYR-GCK GNELVALYRIRVGRRISSAALVADGLHARTDGFTSLAVLLGAGG-VALGF
Mvan_3726|M.vanbaalenii_PYR-1 GNELVAVYRIRVGRQIGSAALIADGLHARTDGFTSLAVLFGAGG-VALGF
MSMEG_5604|M.smegmatis_MC2_155 IMPVLSYAQRRAGRELGSLSAVADSKQTLLCTYLSAVLLVGLLLNSIFGW
TH_1241|M.thermoresistible__bu IMPVLSYAQRRAGRELGSLSAVADSKQTLLCTYLSAVLLIGLLLNSLFGW
MLBr_00283|M.leprae_Br4923 VTNFVVAPLLRP-HAEDSLAIKGAYMEAVADTVGNIGVLIAGVVTLTTHW
MAB_0183c|M.abscessus_ATCC_199 AVNVAATWCISKANRSS-LNVEGAFQHILNDLYAFIATAVAGAVVWLTGF
. . . . :
MMAR_3313|M.marinum_M GWADGVAGLAVTGFICHVGWEVSSEIGHRLLDGVDP---------GVVDT
MUL_1315|M.ulcerans_Agy99 GWADGVAGLAVTGFICHVGWEVSSEIGHRLLDGVDP---------GVVDT
MAV_3555|M.avium_104 GWADAVAGIVVTGFICHVGWEVTADIAHRLLDGVDP---------DIVTT
Mb2050c|M.bovis_AF2122/97 PLADPIVGLLITAAILAVLRTAARDVFRRLLDGVDP---------AMVDA
Rv2025c|M.tuberculosis_H37Rv PLADPIVGLLITAAILAVLRTAARDVFRRLLDGVDP---------AMVDA
Mflv_1902|M.gilvum_PYR-GCK PLADPVIGLVITVAILAILRTAARDIFRRLMDGVDP---------GFVAS
Mvan_3726|M.vanbaalenii_PYR-1 PLADPIIGLVITVAILAVLRTAVRDIFRRLMDAVDP---------KFVDT
MSMEG_5604|M.smegmatis_MC2_155 SWADPIAGLVIAAVAVREG-------------------------------
TH_1241|M.thermoresistible__bu SWADPVAGLAIAAMAVREG-------------------------------
MLBr_00283|M.leprae_Br4923 PYADVVVAVLVALWVLPRAIS-----------------------------
MAB_0183c|M.abscessus_ATCC_199 TRADAIAALVVAALMLKAGWGLVRESGRIFLEAAPVGLDPGTIGTQLAAV
** : .: ::
MMAR_3313|M.marinum_M AEAVAAAIPGVVHAH-ARARWTGRTLRVEVEGWVDPAMSVADADDIGRRV
MUL_1315|M.ulcerans_Agy99 AEAVAAAIPGVVHAH-ARARWTGRTLRVEVEGWADPAMSVADADDIGRRV
MAV_3555|M.avium_104 AEAVAVSVPGVTHAH-ARARWTGRTLRVEVEGFLDAATSLSDSDRIGRSV
Mb2050c|M.bovis_AF2122/97 AEQALAARPGVQAVRSVRMRWIGHRLHADAELDVDPALDLAQAHRIAHDA
Rv2025c|M.tuberculosis_H37Rv AEQALAARPGVQAVRSVRMRWIGHRLHADAELDVDPALDLAQAHRIAHDA
Mflv_1902|M.gilvum_PYR-GCK AESALAAEPGVLAVRSVRMRWVGHRLHADAELDIDPAVSLADAHRIAHEA
Mvan_3726|M.vanbaalenii_PYR-1 AEAALAAEPGVTGVRSVKMRWMGHRLHADAELDIDPATSLSEAHRIAHDA
MSMEG_5604|M.smegmatis_MC2_155 -----------------LEAWKGDTCCSAG--------------------
TH_1241|M.thermoresistible__bu -----------------IEAWRGDTCCAVPVGTSRTATESGCGCGDDRE-
MLBr_00283|M.leprae_Br4923 ---------------------LARAACGSFPNCRRPTIDVEALRSALGRR
MAB_0183c|M.abscessus_ATCC_199 HAVAEVHDLHIWQITSGQPALSAHILVAPNADCHGIRREIEELLHTQYDI
.
MMAR_3313|M.marinum_M ADQLGARLPQMRSFSWAARGVPLG------------------
MUL_1315|M.ulcerans_Agy99 ADQLGARLPQMRSFSWAARGVPLG------------------
MAV_3555|M.avium_104 AAALAPRLPQMQSFTWTARAA---------------------
Mb2050c|M.bovis_AF2122/97 EHELTHTVPKLTTALIHAYPAEHGSSIPDRGRTVE-------
Rv2025c|M.tuberculosis_H37Rv EHELTHTVPKLTTALIHAYPAEHGSSIPDRGRTVE-------
Mflv_1902|M.gilvum_PYR-GCK EHTLTHAVPKLASALVHAYPDSGGS-----------SH----
Mvan_3726|M.vanbaalenii_PYR-1 EHTLTHAVPKLSSALVHAYPAGGSTEPEDHRHDVEPSHPHQQ
MSMEG_5604|M.smegmatis_MC2_155 ------------------------------------------
TH_1241|M.thermoresistible__bu ------------------------------------------
MLBr_00283|M.leprae_Br4923 RRHRSARPARVNTFARRRYVPPRT------------------
MAB_0183c|M.abscessus_ATCC_199 DHTTLQVDHEGTEASTHCFDPHGEPYRADGSALPGKG-----