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M. bovis AF2122 / 97 Mb2050c (-)

annotation: hypothetical protein Mb2050c
coordinates: 2254664 - 2255662
length: 332

MTHDHAHSRGVPAMIKEIFAPHSHDAADSVDDTLESTAAGIRTVKISLLVLGLTALIQIVIVVMSGSVAL
AADTIHNFADALTAVPLWIAFALGAKPATRRYTYGFGRVEDLAGSFVVAMITMSAIIAGYEAIARLIHPQ
QIEHVGWVALAGLVGFIGNEWVALYRIRVGHRIGSAALIADGLHARTDGFTSLAVLCSAGGVALGFPLAD
PIVGLLITAAILAVLRTAARDVFRRLLDGVDPAMVDAAEQALAARPGVQAVRSVRMRWIGHRLHADAELD
VDPALDLAQAHRIAHDAEHELTHTVPKLTTALIHAYPAEHGSSIPDRGRTVE
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2050c--100% (332)hypothetical protein Mb2050c

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_1902-1e-14177.16% (324) cation diffusion facilitator family transporter
M. tuberculosis H37RvRv2025c-0.0100.00% (332) hypothetical protein Rv2025c
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_0183c-3e-1429.77% (299) putative cation transporter
M. marinum MMMAR_3313-1e-5240.56% (286) hypothetical protein MMAR_3313
M. avium 104MAV_3555-9e-5038.57% (280) cation efflux family protein
M. smegmatis MC2 155MSMEG_0755-3e-1126.06% (284) cobalt-zinc-cadmium resistance protein
M. thermoresistible (build 8)-----
M. ulcerans Agy99MUL_1315-2e-4840.23% (256) hypothetical protein MUL_1315
M. vanbaalenii PYR-1Mvan_3726-1e-14074.12% (340) cation diffusion facilitator family transporter

CLUSTAL 2.0.9 multiple sequence alignment


Mb2050c|M.bovis_AF2122/97           MTHD-------------------------------------HAHSRG---
Rv2025c|M.tuberculosis_H37Rv        MTHD-------------------------------------HAHSRG---
Mflv_1902|M.gilvum_PYR-GCK          MTHD-----------AHAH--------HDHGSGHDH-----HPHSHSGRG
Mvan_3726|M.vanbaalenii_PYR-1       MAHEPIAATDPHEGNSHADNDGHDQGSHDHGEGHSHDHDHGHGHSHDGWG
MMAR_3313|M.marinum_M               --------------------------------------------------
MUL_1315|M.ulcerans_Agy99           --------------------------------------------------
MAV_3555|M.avium_104                --------------------------------------------------
MAB_0183c|M.abscessus_ATCC_199      --------------------------------------------------
MSMEG_0755|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

Mb2050c|M.bovis_AF2122/97           --VPAMIKEIFAPHSHDAADSVDDTLESTAAGIRTVKISLLVLGLTALIQ
Rv2025c|M.tuberculosis_H37Rv        --VPAMIKEIFAPHSHDAADSVDDTLESTAAGIRTVKISLLVLGLTALIQ
Mflv_1902|M.gilvum_PYR-GCK          GKIGAALREVFAPHSHDASDSIDSALESSAAGIRAVKISLLVLGVTAIAQ
Mvan_3726|M.vanbaalenii_PYR-1       GKFGAAIREVFAPHSHDASDSIDGALESSAAGIRAVKISLLALGVTAIAQ
MMAR_3313|M.marinum_M               --MHLVDGQRDPAASFPLAQAVDDQAERRRA-NRAVAVSAAGLGLTGLIE
MUL_1315|M.ulcerans_Agy99           --------------------------------------------MTGLIE
MAV_3555|M.avium_104                --MHVINGVRDPAASFPLDTATDDAGERRQA-NRAVAVSAAGLALTGLVE
MAB_0183c|M.abscessus_ATCC_199      ---------MAADAHEHGSGHSHGHGVNADADRKWLTIALILIGGFMAIE
MSMEG_0755|M.smegmatis_MC2_155      ----------------MGAGHDHSHHTDARVSR--MLVAAAILTAFFFVE
                                                                                     :

Mb2050c|M.bovis_AF2122/97           IVIVVMSGSVALAADTIHNFADALTAVPLWIAFALGAKPATR-RYTYGFG
Rv2025c|M.tuberculosis_H37Rv        IVIVVMSGSVALAADTIHNFADALTAVPLWIAFALGAKPATR-RYTYGFG
Mflv_1902|M.gilvum_PYR-GCK          IAIVAISGSVALLADTIHNFSDALTAIPLWIAFALSTKAATR-RYTYGFG
Mvan_3726|M.vanbaalenii_PYR-1       IVIVVISSSVALLADTIHNFSDALTAVPLWIAFALSTKAATR-RYTYGFG
MMAR_3313|M.marinum_M               LAIALVSGSVALLGDALHNLSDVSTSLVVFVGFRSSRKSASE-RYPYGLE
MUL_1315|M.ulcerans_Agy99           LAIALVSGSVALLGDALHNLYDVSTSLVVFVGFRSSRKSASE-RYPYGLE
MAV_3555|M.avium_104                LVIAVVSGSVALLGDALHNLSDVSTSALVFVGFRASRKLPTE-RYPYGYE
MAB_0183c|M.abscessus_ATCC_199      VVIGIIAQSLALISDAGHMLTDAASIVLALIAIRLSSRPARG-SYTFGLK
MSMEG_0755|M.smegmatis_MC2_155      LITALMINSIALLADAGHMLTDLVAMFMGLTAVLLARRGSTSPARTFGWH
                                    :    :  *:** .*: * : *  :      ..  . : .     .:*  

Mb2050c|M.bovis_AF2122/97           RVEDLAGSFVVAMITMSAIIAGYEAIARLIHPQQIEHVGWVALAGLVGFI
Rv2025c|M.tuberculosis_H37Rv        RVEDLAGSFVVAMITMSAIIAGYEAIARLIHPQQIEHVGWVALAGLVGFI
Mflv_1902|M.gilvum_PYR-GCK          RAEDLAGLFVVAMIALSAIIAGVESVRRLINPVPIEHVGWVALAGLVGFI
Mvan_3726|M.vanbaalenii_PYR-1       RAEDLAGLFVVAMITLSAIIAGIESIRRLINPVPIEHVGWVAAAGLVGFI
MMAR_3313|M.marinum_M               RAEDLAGIGVALVIWASAAVAGTESVGKLLRHGSTQHVGWGIAAAAVGIV
MUL_1315|M.ulcerans_Agy99           RAEDLAGIGVALVIWASAAVAGTESVGKLLRHGSTQHVGWGIAAAAVGIV
MAV_3555|M.avium_104                RAEDLAGIGVALVIWGSAVVAGFESVTKLLRHGGTGHVGWGIAAAVVGVV
MAB_0183c|M.abscessus_ATCC_199      RAEILSAQANGVTLFLLAAFFIYEGIRRLITPPEVSGL-LVFITALAGIA
MSMEG_0755|M.smegmatis_MC2_155      RAEVFTAVANAALLIGVAGFILYEAFERLGNAPEVPGV-PMIVVALAGLI
                                    *.* ::.      :   * .   *.. :*        :     .. .*. 

Mb2050c|M.bovis_AF2122/97           GNEWVALYRIRVGHRIGSAALIADGLHARTDGFTSLAVLCS-AGGVALGF
Rv2025c|M.tuberculosis_H37Rv        GNEWVALYRIRVGHRIGSAALIADGLHARTDGFTSLAVLCS-AGGVALGF
Mflv_1902|M.gilvum_PYR-GCK          GNELVALYRIRVGRRISSAALVADGLHARTDGFTSLAVLLG-AGGVALGF
Mvan_3726|M.vanbaalenii_PYR-1       GNELVAVYRIRVGRQIGSAALIADGLHARTDGFTSLAVLFG-AGGVALGF
MMAR_3313|M.marinum_M               GNQLVARYKLVVGRRIQSSTMIADAKHSWLDALSSAGALLG-LCGVAKGW
MUL_1315|M.ulcerans_Agy99           GNQLVARYKLVVGRRIQSSTMIADAKHSWLDALSSAGALLG-LCGVAMGW
MAV_3555|M.avium_104                GNQLVARYKLVVGRRIRSATMVADAKHSWLDALSSAGAVLG-LIGVALGW
MAB_0183c|M.abscessus_ATCC_199      VNVAATWCISKANR--SSLNVEGAFQHILNDLYAFIATAVAGAVVWLTGF
MSMEG_0755|M.smegmatis_MC2_155      ANAAVVLMLRSHSK--DSLAVKGAYMEVVADTVGSIGVLIAGIVTVTTGW
                                     *  ..      .:   *  : .   .   *     ..  .       *:

Mb2050c|M.bovis_AF2122/97           PLADPIVGLLITAAILAVLRTAARDVFRRLLDG----VDPAMVDAAEQAL
Rv2025c|M.tuberculosis_H37Rv        PLADPIVGLLITAAILAVLRTAARDVFRRLLDG----VDPAMVDAAEQAL
Mflv_1902|M.gilvum_PYR-GCK          PLADPVIGLVITVAILAILRTAARDIFRRLMDG----VDPGFVASAESAL
Mvan_3726|M.vanbaalenii_PYR-1       PLADPIIGLVITVAILAVLRTAVRDIFRRLMDA----VDPKFVDTAEAAL
MMAR_3313|M.marinum_M               GWADGVAGLAVTGFICHVGWEVSSEIGHRLLDG----VDPGVVDTAEAVA
MUL_1315|M.ulcerans_Agy99           GWADGVAGLAVTGFICHVGWEVSSEIGHRLLDG----VDPGVVDTAEAVA
MAV_3555|M.avium_104                GWADAVAGIVVTGFICHVGWEVTADIAHRLLDG----VDPDIVTTAEAVA
MAB_0183c|M.abscessus_ATCC_199      TRADAIAALVVAALMLKAGWGLVRESGRIFLEAAPVGLDPGTIGTQLAAV
MSMEG_0755|M.smegmatis_MC2_155      PYADVVVAVLVALWVLPRAIALARAALRILSESSPAHIDVEKLRSALCAV
                                      ** : .: ::  :            : : :.    :*   : :   . 

Mb2050c|M.bovis_AF2122/97           AARPGVQAVRSVRMRWIGHRLHADAELDVDPALD-----LAQAHRIAHDA
Rv2025c|M.tuberculosis_H37Rv        AARPGVQAVRSVRMRWIGHRLHADAELDVDPALD-----LAQAHRIAHDA
Mflv_1902|M.gilvum_PYR-GCK          AAEPGVLAVRSVRMRWVGHRLHADAELDIDPAVS-----LADAHRIAHEA
Mvan_3726|M.vanbaalenii_PYR-1       AAEPGVTGVRSVKMRWMGHRLHADAELDIDPATS-----LSEAHRIAHDA
MMAR_3313|M.marinum_M               AAIPGVVHAH-ARARWTGRTLRVEVEGWVDPAMS-----VADADDIGRRV
MUL_1315|M.ulcerans_Agy99           AAIPGVVHAH-ARARWTGRTLRVEVEGWADPAMS-----VADADDIGRRV
MAV_3555|M.avium_104                VSVPGVTHAH-ARARWTGRTLRVEVEGFLDAATS-----LSDSDRIGRSV
MAB_0183c|M.abscessus_ATCC_199      HAVAEVHDLHIWQITSGQPALSAHILVAPNADCHGIRREIEELLHTQYDI
MSMEG_0755|M.smegmatis_MC2_155      DGVTDVHDLHVWTLVPGKDMVTAHLTSDADTAR---VLDDARAVLTAHGL
                                     . . *   :          : ..     :.                   

Mb2050c|M.bovis_AF2122/97           EHELTHTVPKLTTALIHAYPAEHGSSIPDRGRTVE-------
Rv2025c|M.tuberculosis_H37Rv        EHELTHTVPKLTTALIHAYPAEHGSSIPDRGRTVE-------
Mflv_1902|M.gilvum_PYR-GCK          EHTLTHAVPKLASALVHAYPDSGGS-----------SH----
Mvan_3726|M.vanbaalenii_PYR-1       EHTLTHAVPKLSSALVHAYPAGGSTEPEDHRHDVEPSHPHQQ
MMAR_3313|M.marinum_M               ADQLGARLPQMRSFSWAARGVPLG------------------
MUL_1315|M.ulcerans_Agy99           ADQLGARLPQMRSFSWAARGVPLG------------------
MAV_3555|M.avium_104                AAALAPRLPQMQSFTWTARAA---------------------
MAB_0183c|M.abscessus_ATCC_199      DHTTLQVDHEGTEASTHCFDPHGEPYRADGSALPGKG-----
MSMEG_0755|M.smegmatis_MC2_155      EHATVQVEPPDAAGDCRCEAE---------------------
                                                     .