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M. leprae Br4923 MLBr_00283 (-)

annotation: putative cation-efflux transporter component
coordinates: 364932 - 365738
length: 268

LQCMRKHAYIAHMGSGGSYTPAEAAIYRMIRRMIVAAAILMVFFGVELTIALLINSITLLADAGHMLTDV
VAVFMGLAALVLAKHGHSAPNRPYSWHRAEVFTAMANAALLIGVATFILYEAIRRFKEAPYIPGMPIVVA
ALAGLVTNFVVAPLLRPHAEDSLAIKGAYMEAVADTVGNIGVLIAGVVTLTTHWPYADVVVAVLVALWVL
PRAISLARAACGSFPNCRRPTIDVEALRSALGRRRRHRSARPARVNTFARRRYVPPRT
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. leprae Br4923MLBr_00283--100% (268)putative cation-efflux transporter component

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCKMflv_0231-8e-7867.45% (212) cation diffusion facilitator family transporter
M. tuberculosis H37Rv-----
M. abscessus ATCC 19977MAB_0183c-4e-2331.22% (189) putative cation transporter
M. marinum MMMAR_0677-1e-8470.31% (229) efflux membrane protein
M. avium 104MAV_4782-3e-8569.57% (230) cobalt-zinc-cadmium resistance protein
M. smegmatis MC2 155MSMEG_0755-3e-7765.50% (229) cobalt-zinc-cadmium resistance protein
M. thermoresistible (build 8)-----
M. ulcerans Agy99MUL_2837-1e-8470.31% (229) efflux membrane protein
M. vanbaalenii PYR-1Mvan_0673-6e-7869.01% (213) cation diffusion facilitator family transporter

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0231|M.gilvum_PYR-GCK          -----MRIYFWPMGAGHDHSHGGG--DTKVSRMVIAAGILTIFFVVELTT
Mvan_0673|M.vanbaalenii_PYR-1       ------------MGAGHDHSHGG---DTKVSRMVLGAAILTVFFIVELST
MSMEG_0755|M.smegmatis_MC2_155      ------------MGAGHDHSHHT---DARVSRMLVAAAILTAFFFVELIT
MMAR_0677|M.marinum_M               ------------MGAGHNHTPATAYASRMIPRMVCAATILAMFFVVELTT
MUL_2837|M.ulcerans_Agy99           ------------MGAGHNHTPATAYASRMIPRMVCAATILAMFFVVELTT
MAV_4782|M.avium_104                ------------MGAGHNHTPAETGDARLIPRMVMAAAILAAFFVVELVT
MLBr_00283|M.leprae_Br4923          MQCMRKHAYIAHMGSGGSYTPAEAAIYRMIRRMIVAAAILMVFFGVELTI
MAB_0183c|M.abscessus_ATCC_199      -----MAADAHEHGSGHSHGHGVN-ADADRKWLTIALILIGGFMAIEVVI
                                                 *:* .:             :  .  ::  *: :*:  

Mflv_0231|M.gilvum_PYR-GCK          ALAINSIALLADAGHMLTDLVSMFMGLTAVLLAKRGSASPSRTYGWHRAE
Mvan_0673|M.vanbaalenii_PYR-1       ALAINSIALLADAGHMLTDLVAMFMGLTAVLLARRGSTSPSRTYGWHRAE
MSMEG_0755|M.smegmatis_MC2_155      ALMINSIALLADAGHMLTDLVAMFMGLTAVLLARRGSTSPARTFGWHRAE
MMAR_0677|M.marinum_M               AWLINSIALLADAGHMLTDVVAVFMGLAAVILGRRGSSSPNRTYGWHRAE
MUL_2837|M.ulcerans_Agy99           AWLINSIALLADAGHMLTDVVAVFMGLAAVILGRRGSSSPNRTYGWHRAE
MAV_4782|M.avium_104                SLLINSIALLADAGHMLTDVVAVFMGLAAVTLARRGSSSPARTYGWHRAE
MLBr_00283|M.leprae_Br4923          ALLINSITLLADAGHMLTDVVAVFMGLAALVLAKHGHSAPNRPYSWHRAE
MAB_0183c|M.abscessus_ATCC_199      GIIAQSLALISDAGHMLTDAASIVLALIAIRLSSRPARG-SYTFGLKRAE
                                    .   :*::*::******** .::.:.* *: *. :   .   .:. :***

Mflv_0231|M.gilvum_PYR-GCK          VFTAVANAALLLGVAGFILYEAVERLGDAPDVPGVPMIVVALAGLLANLI
Mvan_0673|M.vanbaalenii_PYR-1       VFTAVANAALLFGVAGFILYEAFERLGDAPDVPGVPMIVVALAGLLANAV
MSMEG_0755|M.smegmatis_MC2_155      VFTAVANAALLIGVAGFILYEAFERLGNAPEVPGVPMIVVALAGLIANAA
MMAR_0677|M.marinum_M               VFTAVANAALLIGVALFIVYEAIDRLREAPSVPGLPMIVVALAGLSANIV
MUL_2837|M.ulcerans_Agy99           VFTAVANAALLIGVALFIVYEAIDRLREAPSVPGLPMIVVALAGLSANIV
MAV_4782|M.avium_104                VFTAVANAGLLIGVSVFILYEAIQRLREAPAVPGVPMIVVALAGLAANFV
MLBr_00283|M.leprae_Br4923          VFTAMANAALLIGVATFILYEAIRRFKEAPYIPGMPIVVAALAGLVTNFV
MAB_0183c|M.abscessus_ATCC_199      ILSAQANGVTLFLLAAFFIYEGIRRLITPPEVSGLLVFITALAGIAVNVA
                                    :::* **.  *: :: *::**.. *:  .* :.*: :.:.****: .*  

Mflv_0231|M.gilvum_PYR-GCK          VVLLLRSHSKESLAVKGAYMEVVADTVGSIGVLIAGIVTVTTAWPYADVV
Mvan_0673|M.vanbaalenii_PYR-1       VVLLLRSHSKESLAVKGAYMEVVADTVGSIGVLIAGIVTVTTRWPYADVV
MSMEG_0755|M.smegmatis_MC2_155      VVLMLRSHSKDSLAVKGAYMEVVADTVGSIGVLIAGIVTVTTGWPYADVV
MMAR_0677|M.marinum_M               VALLLRSHADSSLAVKGAYMEVVADTVGSLGVLAAGVVTVTTSWPYADVV
MUL_2837|M.ulcerans_Agy99           VALLLRSHADSSLAVKGAYMEVVADTVGSLGVLAAGVVTVTTSWPYADVV
MAV_4782|M.avium_104                VALLLRSHSSGSLAVKGAYLEVIADTVGSLGVLIAGVVTVTTRWPYADVV
MLBr_00283|M.leprae_Br4923          VAPLLRPHAEDSLAIKGAYMEAVADTVGNIGVLIAGVVTLTTHWPYADVV
MAB_0183c|M.abscessus_ATCC_199      ATWCISKANRSSLNVEGAFQHILNDLYAFIATAVAGAVVWLTGFTRADAI
                                    ..  :      ** ::**: . : *  . :..  ** *.  * :. **.:

Mflv_0231|M.gilvum_PYR-GCK          VAVLVALWVLPRAIALARAALRILSESSPAHIDVDELRDALCAVDGVTEV
Mvan_0673|M.vanbaalenii_PYR-1       VAVLVALWVLPRAISLARAALRILSESSPRHIDVEELRAALGAVDGVTEV
MSMEG_0755|M.smegmatis_MC2_155      VAVLVALWVLPRAIALARAALRILSESSPAHIDVEKLRSALCAVDGVTDV
MMAR_0677|M.marinum_M               VAVLVALWVAPRAVSLARAALRILSESSPRHIDVDELRSALRAVDGVTEV
MUL_2837|M.ulcerans_Agy99           VAVLVALWVAPRAVSLARAALRILSESSPRHIDVDELRSALRAVDGVTEV
MAV_4782|M.avium_104                VAVLVALWVLPRAISLARDALRILSESSPTHIDVEELRAALGAVDGVTGV
MLBr_00283|M.leprae_Br4923          VAVLVALWVLPRAISLARAACGSFPNCRRPTIDVEALRSALGRRRRHRSA
MAB_0183c|M.abscessus_ATCC_199      AALVVAALMLKAGWGLVRESGRIFLEAAPVGLDPGTIGTQLAAVHAVAEV
                                    .*::**  :   . .*.* :   : :.    :*   :   *        .

Mflv_0231|M.gilvum_PYR-GCK          HDLHVWTLVPGKDMVTAHLTSVRESAAV---LDDARAVLTARGLGHATVQ
Mvan_0673|M.vanbaalenii_PYR-1       HDLHVWTLVPGKDMVTAHLTSDRDSAQI---LDDARAVLAARGLDHSTVQ
MSMEG_0755|M.smegmatis_MC2_155      HDLHVWTLVPGKDMVTAHLTSDADTARV---LDDARAVLTAHGLEHATVQ
MMAR_0677|M.marinum_M               HDLHVWTLAPGKDMATAHLTSSADSARV---LHDARAVLSDRGLHHATVQ
MUL_2837|M.ulcerans_Agy99           HDLHVWTLAPGKDMATAHLTSSADSARV---LHDARAVLSDRGLHHATVQ
MAV_4782|M.avium_104                HDLHVWTLSPGKDMCTAHLISTGDSARV---LRDARAVLSARGLAHATVQ
MLBr_00283|M.leprae_Br4923          RPARVNTFAR-------------------------RRYVPPRT-------
MAB_0183c|M.abscessus_ATCC_199      HDLHIWQITSGQPALSAHILVAPNADCHGIRREIEELLHTQYDIDHTTLQ
                                    :  ::  :                           .   .          

Mflv_0231|M.gilvum_PYR-GCK          VEPPDSAADCECETEKR--------------
Mvan_0673|M.vanbaalenii_PYR-1       VEPPDTAADCECESRKR--------------
MSMEG_0755|M.smegmatis_MC2_155      VEPPDAAGDCRCEAE----------------
MMAR_0677|M.marinum_M               IEHTAGIQECPDSCSDAVPAIG---------
MUL_2837|M.ulcerans_Agy99           IEHTAGIQECPDSCSDAVPAIG---------
MAV_4782|M.avium_104                IDCPDDT-ECSDSF-----------------
MLBr_00283|M.leprae_Br4923          -------------------------------
MAB_0183c|M.abscessus_ATCC_199      VDHEGTEASTHCFDPHGEPYRADGSALPGKG