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MSHATGAAAHPQNHDHPHHHDHDHPHDHGHPHGGKLRTVIREVFAPHSHDASDSIDDALESSAAGIRAVK ISLLVLGATTVGQLAIVAVSGSVALLADTIHNFSDAMTAIPLWIAFALGTRAATRRYTYGFGRAEDIAGL FVVAMIALSAVVAGVESIRRLINPVAIEHVGWVAAAGLVGFLGNEIVAVYRIRVGRRIGSAALVADGLHA RTDGFTSLAVVLGAAGAALGFPLADPIVGLLITVAILAVLRTAVRDVFRRLMDGVDPAFVDSAEAALAAE PGVSQVRTVRMRWIGHRLHAEAELDIDPAVTLADAHRIAHRAEHTLTHAVPKLSTALVHAYPGSSDRGAR GGSSVG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3225 | - | - | 100% (356) | cation diffusion facilitator family transporter |
| M. vanbaalenii PYR-1 | Mvan_3726 | - | e-158 | 79.65% (344) | cation diffusion facilitator family transporter |
| M. vanbaalenii PYR-1 | Mvan_5864 | - | 8e-19 | 28.28% (290) | cation diffusion facilitator family transporter |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2050c | - | 1e-139 | 75.00% (332) | hypothetical protein Mb2050c |
| M. gilvum PYR-GCK | Mflv_1902 | - | 1e-158 | 81.21% (346) | cation diffusion facilitator family transporter |
| M. tuberculosis H37Rv | Rv2025c | - | 1e-139 | 75.00% (332) | hypothetical protein Rv2025c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0183c | - | 4e-12 | 26.87% (294) | putative cation transporter |
| M. marinum M | MMAR_3313 | - | 2e-56 | 42.31% (286) | hypothetical protein MMAR_3313 |
| M. avium 104 | MAV_3555 | - | 1e-54 | 42.50% (280) | cation efflux family protein |
| M. smegmatis MC2 155 | MSMEG_0755 | - | 4e-10 | 27.36% (296) | cobalt-zinc-cadmium resistance protein |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_1315 | - | 4e-52 | 43.03% (251) | hypothetical protein MUL_1315 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_3225|M.vanbaalenii_PYR-1 MSHATGAAAHPQNHDHPHHHDHDHPHDHGHPHGGKLRTVIREVFAPHSHD
Mflv_1902|M.gilvum_PYR-GCK MTHD--AHAH---HDHGSGHDH-HPHSHSG-RGGKIGAALREVFAPHSHD
Mb2050c|M.bovis_AF2122/97 MTHD-------------------HAHSR------GVPAMIKEIFAPHSHD
Rv2025c|M.tuberculosis_H37Rv MTHD-------------------HAHSR------GVPAMIKEIFAPHSHD
MMAR_3313|M.marinum_M -----------------------------------MHLVDGQRDPAASFP
MUL_1315|M.ulcerans_Agy99 --------------------------------------------------
MAV_3555|M.avium_104 -----------------------------------MHVINGVRDPAASFP
MAB_0183c|M.abscessus_ATCC_199 ------------------------------------------MAADAHEH
MSMEG_0755|M.smegmatis_MC2_155 -------------------------------------------------M
Mvan_3225|M.vanbaalenii_PYR-1 ASDSIDDALESSAAGIRAVKISLLVLGATTVGQLAIVAVSGSVALLADTI
Mflv_1902|M.gilvum_PYR-GCK ASDSIDSALESSAAGIRAVKISLLVLGVTAIAQIAIVAISGSVALLADTI
Mb2050c|M.bovis_AF2122/97 AADSVDDTLESTAAGIRTVKISLLVLGLTALIQIVIVVMSGSVALAADTI
Rv2025c|M.tuberculosis_H37Rv AADSVDDTLESTAAGIRTVKISLLVLGLTALIQIVIVVMSGSVALAADTI
MMAR_3313|M.marinum_M LAQAVDDQAERRRA-NRAVAVSAAGLGLTGLIELAIALVSGSVALLGDAL
MUL_1315|M.ulcerans_Agy99 ---------------------------MTGLIELAIALVSGSVALLGDAL
MAV_3555|M.avium_104 LDTATDDAGERRQA-NRAVAVSAAGLALTGLVELVIAVVSGSVALLGDAL
MAB_0183c|M.abscessus_ATCC_199 GSGHSHGHGVNADADRKWLTIALILIGGFMAIEVVIGIIAQSLALISDAG
MSMEG_0755|M.smegmatis_MC2_155 GAGHDHSHHTDARVSR--MLVAAAILTAFFFVELITALMINSIALLADAG
:: : *:** .*:
Mvan_3225|M.vanbaalenii_PYR-1 HNFSDAMTAIPLWIAFALGTRAATR-RYTYGFGRAEDIAGLFVVAMIALS
Mflv_1902|M.gilvum_PYR-GCK HNFSDALTAIPLWIAFALSTKAATR-RYTYGFGRAEDLAGLFVVAMIALS
Mb2050c|M.bovis_AF2122/97 HNFADALTAVPLWIAFALGAKPATR-RYTYGFGRVEDLAGSFVVAMITMS
Rv2025c|M.tuberculosis_H37Rv HNFADALTAVPLWIAFALGAKPATR-RYTYGFGRVEDLAGSFVVAMITMS
MMAR_3313|M.marinum_M HNLSDVSTSLVVFVGFRSSRKSASE-RYPYGLERAEDLAGIGVALVIWAS
MUL_1315|M.ulcerans_Agy99 HNLYDVSTSLVVFVGFRSSRKSASE-RYPYGLERAEDLAGIGVALVIWAS
MAV_3555|M.avium_104 HNLSDVSTSALVFVGFRASRKLPTE-RYPYGYERAEDLAGIGVALVIWGS
MAB_0183c|M.abscessus_ATCC_199 HMLTDAASIVLALIAIRLSSRPARG-SYTFGLKRAEILSAQANGVTLFLL
MSMEG_0755|M.smegmatis_MC2_155 HMLTDLVAMFMGLTAVLLARRGSTSPARTFGWHRAEVFTAVANAALLIGV
* : * : .. . : . .:* *.* ::. :
Mvan_3225|M.vanbaalenii_PYR-1 AVVAGVESIRRLINPVAIEHVGWVAAAGLVGFLGNEIVAVYRIRVGRRIG
Mflv_1902|M.gilvum_PYR-GCK AIIAGVESVRRLINPVPIEHVGWVALAGLVGFIGNELVALYRIRVGRRIS
Mb2050c|M.bovis_AF2122/97 AIIAGYEAIARLIHPQQIEHVGWVALAGLVGFIGNEWVALYRIRVGHRIG
Rv2025c|M.tuberculosis_H37Rv AIIAGYEAIARLIHPQQIEHVGWVALAGLVGFIGNEWVALYRIRVGHRIG
MMAR_3313|M.marinum_M AAVAGTESVGKLLRHGSTQHVGWGIAAAAVGIVGNQLVARYKLVVGRRIQ
MUL_1315|M.ulcerans_Agy99 AAVAGTESVGKLLRHGSTQHVGWGIAAAAVGIVGNQLVARYKLVVGRRIQ
MAV_3555|M.avium_104 AVVAGFESVTKLLRHGGTGHVGWGIAAAVVGVVGNQLVARYKLVVGRRIR
MAB_0183c|M.abscessus_ATCC_199 AAFFIYEGIRRLITPPEVSGL-LVFITALAGIAVNVAATWCISKANR--S
MSMEG_0755|M.smegmatis_MC2_155 AGFILYEAFERLGNAPEVPGV-PMIVVALAGLIANAAVVLMLRSHSK--D
* . *.. :* : .. .*. * .. .:
Mvan_3225|M.vanbaalenii_PYR-1 SAALVADGLHARTDGFTSLAVVLG-AAGAALGFPLADPIVGLLITVAILA
Mflv_1902|M.gilvum_PYR-GCK SAALVADGLHARTDGFTSLAVLLG-AGGVALGFPLADPVIGLVITVAILA
Mb2050c|M.bovis_AF2122/97 SAALIADGLHARTDGFTSLAVLCS-AGGVALGFPLADPIVGLLITAAILA
Rv2025c|M.tuberculosis_H37Rv SAALIADGLHARTDGFTSLAVLCS-AGGVALGFPLADPIVGLLITAAILA
MMAR_3313|M.marinum_M SSTMIADAKHSWLDALSSAGALLG-LCGVAKGWGWADGVAGLAVTGFICH
MUL_1315|M.ulcerans_Agy99 SSTMIADAKHSWLDALSSAGALLG-LCGVAMGWGWADGVAGLAVTGFICH
MAV_3555|M.avium_104 SATMVADAKHSWLDALSSAGAVLG-LIGVALGWGWADAVAGIVVTGFICH
MAB_0183c|M.abscessus_ATCC_199 SLNVEGAFQHILNDLYAFIATAVAGAVVWLTGFTRADAIAALVVAALMLK
MSMEG_0755|M.smegmatis_MC2_155 SLAVKGAYMEVVADTVGSIGVLIAGIVTVTTGWPYADVVVAVLVALWVLP
* : . . * .. . *: ** : .: :: :
Mvan_3225|M.vanbaalenii_PYR-1 VLRTAVRDVFRRLMDG----VDPAFVDSAEAALAAEPGVSQVRTVRMRWI
Mflv_1902|M.gilvum_PYR-GCK ILRTAARDIFRRLMDG----VDPGFVASAESALAAEPGVLAVRSVRMRWV
Mb2050c|M.bovis_AF2122/97 VLRTAARDVFRRLLDG----VDPAMVDAAEQALAARPGVQAVRSVRMRWI
Rv2025c|M.tuberculosis_H37Rv VLRTAARDVFRRLLDG----VDPAMVDAAEQALAARPGVQAVRSVRMRWI
MMAR_3313|M.marinum_M VGWEVSSEIGHRLLDG----VDPGVVDTAEAVAAAIPGVVHAH-ARARWT
MUL_1315|M.ulcerans_Agy99 VGWEVSSEIGHRLLDG----VDPGVVDTAEAVAAAIPGVVHAH-ARARWT
MAV_3555|M.avium_104 VGWEVTADIAHRLLDG----VDPDIVTTAEAVAVSVPGVTHAH-ARARWT
MAB_0183c|M.abscessus_ATCC_199 AGWGLVRESGRIFLEAAPVGLDPGTIGTQLAAVHAVAEVHDLHIWQITSG
MSMEG_0755|M.smegmatis_MC2_155 RAIALARAALRILSESSPAHIDVEKLRSALCAVDGVTDVHDLHVWTLVPG
: : :. :* : : . . . * :
Mvan_3225|M.vanbaalenii_PYR-1 GHRLHAEAELDIDPAVT-----LADAHRIAHRAEHTLTHAVPKLSTALVH
Mflv_1902|M.gilvum_PYR-GCK GHRLHADAELDIDPAVS-----LADAHRIAHEAEHTLTHAVPKLASALVH
Mb2050c|M.bovis_AF2122/97 GHRLHADAELDVDPALD-----LAQAHRIAHDAEHELTHTVPKLTTALIH
Rv2025c|M.tuberculosis_H37Rv GHRLHADAELDVDPALD-----LAQAHRIAHDAEHELTHTVPKLTTALIH
MMAR_3313|M.marinum_M GRTLRVEVEGWVDPAMS-----VADADDIGRRVADQLGARLPQMRSFSWA
MUL_1315|M.ulcerans_Agy99 GRTLRVEVEGWADPAMS-----VADADDIGRRVADQLGARLPQMRSFSWA
MAV_3555|M.avium_104 GRTLRVEVEGFLDAATS-----LSDSDRIGRSVAAALAPRLPQMQSFTWT
MAB_0183c|M.abscessus_ATCC_199 QPALSAHILVAPNADCHGIRREIEELLHTQYDIDHTTLQVDHEGTEASTH
MSMEG_0755|M.smegmatis_MC2_155 KDMVTAHLTSDADTAR---VLDDARAVLTAHGLEHATVQVEPPDAAGDCR
: .. :.
Mvan_3225|M.vanbaalenii_PYR-1 AYPGSSDRGA-RGGSSVG--
Mflv_1902|M.gilvum_PYR-GCK AYPDS-------GGSSH---
Mb2050c|M.bovis_AF2122/97 AYPAEHGSSIPDRGRTVE--
Rv2025c|M.tuberculosis_H37Rv AYPAEHGSSIPDRGRTVE--
MMAR_3313|M.marinum_M ARGVPLG-------------
MUL_1315|M.ulcerans_Agy99 ARGVPLG-------------
MAV_3555|M.avium_104 ARAA----------------
MAB_0183c|M.abscessus_ATCC_199 CFDPHGEPYRADGSALPGKG
MSMEG_0755|M.smegmatis_MC2_155 CEAE----------------
.