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MATVRGRPRSFDRDAALDKAIRLFWERGFEATSTRDLSSALGIGMPSIYAAFGDKRQLFAEAVEVYDARY GGFIDAALDQEPTARAAVARILAQAPGRYTRRGLPSGCLIISGDDGSADETVGAALRRIREKKTQTVADK IRADIAAGELPADTDALALAQFVMSTLSGIAQAARDGIPRARLDQVAAIALRAWPQR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2030 | - | - | 100% (197) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_5597 | - | 9e-29 | 38.02% (192) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_1509 | - | 1e-20 | 32.49% (197) | TetR-family protein transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0244 | - | 1e-06 | 25.65% (191) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0944 | - | 2e-19 | 32.97% (185) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0238 | - | 1e-06 | 25.65% (191) | TetR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3199c | - | 2e-07 | 31.87% (91) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0630 | - | 3e-12 | 28.57% (196) | transcriptional regulatory protein |
| M. avium 104 | MAV_0146 | - | 9e-06 | 36.59% (82) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_4110 | - | 5e-09 | 43.75% (64) | PUTATIVE putative transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_1163 | - | 7e-07 | 23.46% (162) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1617 | - | 6e-33 | 40.10% (192) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_2030|M.smegmatis_MC2_155 ------MATVR----GRPRSFDRD-AALDKAIRLFWERGFEATSTRDLSS
Mvan_1617|M.vanbaalenii_PYR-1 ------MGSPGTSSIGRPRSFDTD-EALERAMVVFWAHGYEGASLTDLTE
Mflv_0944|M.gilvum_PYR-GCK --------------MARPRTFDED-EVIEAGRDLFWSQGYAATSIDDLSA
MMAR_0630|M.marinum_M --------------MARPRAFDEA-VVLSAARDEFRSHGYAATSVDSLAA
Mb0244|M.bovis_AF2122/97 ---------MAGGTKRLPRAVREQ-QMLDAAVQMFSVNGYHETSMDAIAA
Rv0238|M.tuberculosis_H37Rv ---------MAGGTKRLPRAVREQ-QMLDAAVQMFSVNGYHETSMDAIAA
MUL_1163|M.ulcerans_Agy99 ---------MAGGTKRLPRAIREQ-QMLDAAVQMFSANGYHETSMDTIAA
MAB_3199c|M.abscessus_ATCC_199 --------MTRAGTKGMPRAERER-QILDAACQEFGRSGYVGMSLAAVAA
MAV_0146|M.avium_104 -----------------MLSSGRD-RLLSAALRLFAAKGYAATSVADIQR
TH_4110|M.thermoresistible__bu VTATDAAATGRAAARGRPRDPALDSAILDAALEIFVEQGISALSIEQVAR
:. . * * * :
MSMEG_2030|M.smegmatis_MC2_155 ALGIG--MPSIYAAFGDKRQLFAEAVEVYDARYGGFIDAAL-DQEPTARA
Mvan_1617|M.vanbaalenii_PYR-1 AMGIT--RTSMYAAFGNKEELFRAALTRYLEGPGGYLSRAL-EES-TARE
Mflv_0944|M.gilvum_PYR-GCK ATGLG--RGSLYKAFGDKHSMFLRGLEQYCTEAIAGIRAELRDQDLSAYD
MMAR_0630|M.marinum_M ATGLN--RSSLYGSFGDKHRLFLRALDGYCEATLHDVREVLRERGVSARQ
Mb0244|M.bovis_AF2122/97 EAQIS--KPMLYLYYGSKEDLFGACLNREMSRFIDALRSSI-NFDQSPKD
Rv0238|M.tuberculosis_H37Rv EAQIS--KPMLYLYYGSKEDLFGACLNREMSRFIDALRSSI-NFDQSPKD
MUL_1163|M.ulcerans_Agy99 AAQIS--KPMLYLYYGSKEDLFGACLNREMSRFIDAVRADI-DLSQSPKD
MAB_3199c|M.abscessus_ATCC_199 AVGVS--KPMVLAYFGSKEQLYIACVERAGATVGDHIEAAM--TAAPPTL
MAV_0146|M.avium_104 ESGLAPGSGALYKHFGSKRELLEAAVAHRIES-IVTAREQYDAGQPGSVE
TH_4110|M.thermoresistible__bu RAGVG--KPTIYRRWSDKEQLVADAIEHRVSAELAWPTPAE-ASVSDPYE
: : :..*. : : .
MSMEG_2030|M.smegmatis_MC2_155 AVARILAQAPGRYTRRGLPSGCLIISG--DDGSADETVG-----------
Mvan_1617|M.vanbaalenii_PYR-1 VAEAFLRGSVRATTRPEGPAGCLVVQGSLAASDAGQPVR-----------
Mflv_0944|M.gilvum_PYR-GCK RLVAHVRGRAADVVSDNDLRGCLLAKSAAELSSTDPEVA-----------
MMAR_0630|M.marinum_M RLINHVHAIVNGIVADTDRRGCMMSRSSAELAGADPDVS-----------
Mb0244|M.bovis_AF2122/97 LLRNTIVSFLR-YIDANRASWIVMYTQATSSQAFAHTVR-----------
Rv0238|M.tuberculosis_H37Rv LLRNTIVSFLR-YIDANRASWIVMYTQATSSQAFAHTVR-----------
MUL_1163|M.ulcerans_Agy99 LLRNAIVSFLR-YIDQNQASWIVMYTQAVSSQAFAQTVR-----------
MAB_3199c|M.abscessus_ATCC_199 ALPRAVLQAIFQALAPRPSDWLVIWDQTLPEGSEALAAARVARTRLAALA
MAV_0146|M.avium_104 QAVRTAGQLIWNNLKQSEDLLKVMLREPDELGDLDEKTWQ----------
TH_4110|M.thermoresistible__bu LVRRNISAAARTAADPAFRGLIAAIYGSAVTHPALLRTY-----------
.
MSMEG_2030|M.smegmatis_MC2_155 -------------------------------------------AALRRIR
Mvan_1617|M.vanbaalenii_PYR-1 -------------------------------------------DALIACR
Mflv_0944|M.gilvum_PYR-GCK -------------------------------------------RHVKRTL
MMAR_0630|M.marinum_M -------------------------------------------GIVERSL
Mb0244|M.bovis_AF2122/97 -------------------------------------------EGREQIV
Rv0238|M.tuberculosis_H37Rv -------------------------------------------EGREQIV
MUL_1163|M.ulcerans_Agy99 -------------------------------------------EGREQIV
MAB_3199c|M.abscessus_ATCC_199 GQGVAAVGSAATQLRDAQDIGVLTQGWMGMVGAMITWWIRHPEQSAEQMA
MAV_0146|M.avium_104 -------------------------------------------VITDNAY
TH_4110|M.thermoresistible__bu ---------------------------------------------WEHYI
MSMEG_2030|M.smegmatis_MC2_155 EKKTQTVADKIRADIAAGELPADTDALALAQFVMSTLSG-----------
Mvan_1617|M.vanbaalenii_PYR-1 EEAVSRLRERFRRAVKDGDLPPGTDPGLLARYLMTVGNG-----------
Mflv_0944|M.gilvum_PYR-GCK DAWLRELTATISAAQADGDIPSSTEAKALAALILAVLRG-----------
MMAR_0630|M.marinum_M EAWRRELADCIAEAQLEGAVAGDGSPQALATVMLSLMQG-----------
Mb0244|M.bovis_AF2122/97 QLVAELVRAGTRGPLTDAEIEMMAVALVGAGEAVATRLG-----------
Rv0238|M.tuberculosis_H37Rv QLVAELVRAGTRGPLTDAEIEMMAVALVGAGEAVATRLG-----------
MUL_1163|M.ulcerans_Agy99 ELVAGMLRAGTRSPRSDAEIDMMAAALVGAGEAVANRLS-----------
MAB_3199c|M.abscessus_ATCC_199 ERASRLIGIIASAGISEAEAPEGGAVPRPGTPVRGSGSGQPLNAAFDLFG
MAV_0146|M.avium_104 QRFADELAASNRAGRTSIPDPEAAAAVAIGSLSYAATLQALTG-------
TH_4110|M.thermoresistible__bu LPRRTAAIALLRRARDLGTVAADADLDVLVDMLAGAVTY-----------
MSMEG_2030|M.smegmatis_MC2_155 ------------------------IAQAARDGIPRARLDQVAAIALRAWP
Mvan_1617|M.vanbaalenii_PYR-1 ------------------------IAVQAASGVARRELQRVADAALRHWP
Mflv_0944|M.gilvum_PYR-GCK ------------------------MEALRKGGASAATVKATAEQLVAML-
MMAR_0630|M.marinum_M ------------------------FEALGKGGVGSAELRAAESAALALLF
Mb0244|M.bovis_AF2122/97 ------------------------IGDTDVDEAAEMMINLFWLGLKGAPV
Rv0238|M.tuberculosis_H37Rv ------------------------IGDTDVDEAAEMMINLFWLGLKGAPV
MUL_1163|M.ulcerans_Agy99 ------------------------AGDTDVDEAAEMMIDLLWRGLKGAPS
MAB_3199c|M.abscessus_ATCC_199 RRWAILVVWELRSGTKTLPELKAEMGDASSSVLATRLKELTAAHIVRNQD
MAV_0146|M.avium_104 ----------------------RLPGNTDEDRYFEAWVNQTVSVLAQYTN
TH_4110|M.thermoresistible__bu -------------------------RVLQPEPPSARQLRCYLEVAYRQVG
MSMEG_2030|M.smegmatis_MC2_155 QR-----------------------------
Mvan_1617|M.vanbaalenii_PYR-1 PA-----------------------------
Mflv_0944|M.gilvum_PYR-GCK -------------------------------
MMAR_0630|M.marinum_M GAGTDPKP-----------------------
Mb0244|M.bovis_AF2122/97 DR-LETGH-----------------------
Rv0238|M.tuberculosis_H37Rv DR-LETGH-----------------------
MUL_1163|M.ulcerans_Agy99 DREIGSNFAAG--------------------
MAB_3199c|M.abscessus_ATCC_199 GQYSLTTVGKGLLVALAPLHLWAKAWSASVR
MAV_0146|M.avium_104 RRKPLNDNDNDSGAQT---------------
TH_4110|M.thermoresistible__bu LLP----------------------------