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MSSKKEWIAALDAVDHAHRAVAGLPFHTLQPADQRALLVRLDALEKLLATRQRQLLAHMVGGPPPVEFAG APWAEVLARRLRISVGEAKRRIEDAGAVPT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5720 | - | - | 100% (100) | hypothetical protein Mvan_5720 |
| M. vanbaalenii PYR-1 | Mvan_3050 | - | 4e-08 | 30.11% (93) | hypothetical protein Mvan_3050 |
| M. vanbaalenii PYR-1 | Mvan_3851 | - | 2e-07 | 28.12% (96) | hypothetical protein Mvan_3851 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1728c | - | 4e-05 | 32.63% (95) | hypothetical protein Mb1728c |
| M. gilvum PYR-GCK | Mflv_1097 | - | 5e-37 | 78.35% (97) | hypothetical protein Mflv_1097 |
| M. tuberculosis H37Rv | Rv1702c | - | 4e-05 | 32.63% (95) | hypothetical protein Rv1702c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0990c | - | 1e-07 | 30.68% (88) | hypothetical protein MAB_0990c |
| M. marinum M | MMAR_1523 | - | 2e-07 | 35.48% (93) | hypothetical protein MMAR_1523 |
| M. avium 104 | MAV_3664 | - | 1e-09 | 43.62% (94) | hypothetical protein MAV_3664 |
| M. smegmatis MC2 155 | MSMEG_2663 | - | 2e-05 | 32.56% (86) | hypothetical protein MSMEG_2663 |
| M. thermoresistible (build 8) | TH_3740 | - | 4e-08 | 32.98% (94) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_2371 | - | 5e-07 | 31.96% (97) | hypothetical protein MUL_2371 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_5720|M.vanbaalenii_PYR-1 -------------MSSKKEWIAALDAVDHAHRAVAGLPFHTLQPADQRAL
Mflv_1097|M.gilvum_PYR-GCK ---MSVPLSRLSNMSSKKEVIAALDAVDRAHRAAAALPFQSLAPADQRAL
Mb1728c|M.bovis_AF2122/97 --------MYS---SSREEAVAAFDNLDTALNRVLKVSPDDLTIPECLAM
Rv1702c|M.tuberculosis_H37Rv --------MYS---SSREEAVAAFDNLDTALNRVLKVSPDDLTIPECLAM
MMAR_1523|M.marinum_M --------MSS---MSREEVVAAFDALDAVMARLQDLCFDGLTTPERLAL
MUL_2371|M.ulcerans_Agy99 --------MHSNGCSDRESVVATLDRLDRAVDALVEVSFEALTTPERLRV
MAB_0990c|M.abscessus_ATCC_199 --------------------MSSIGVVEAAVDAFCAESIEDLTAGEALAM
MAV_3664|M.avium_104 --------MHS--IEVPAEVRAALDALDTADAAIRALDFDALHPVVRLRA
MSMEG_2663|M.smegmatis_MC2_155 -------MIRTSVRYMAAEVGTALAALHAAMRDVLALPYTALSDADLLDV
TH_3740|M.thermoresistible__bu MDSNISGPEPSGAPSARAQWAAVLDELEAAEAALLRAPVHSLSGPQLLEL
: : :. . *
Mvan_5720|M.vanbaalenii_PYR-1 LVRLDALEKLLATRQRQLLAHMVGGPPPVEFAGAPWAEVLARRLRISVGE
Mflv_1097|M.gilvum_PYR-GCK LVRLDAVAKQLAVTQRRLLGQMVAGPPPVELAGAPWAEVLARRLRISVGE
Mb1728c|M.bovis_AF2122/97 LQRCEKIRRRLPAAEHPFINKLADQTDQTELGG-KLPFALAERLHISRGE
Rv1702c|M.tuberculosis_H37Rv LQRCEKIRRRLPAAEHPFINKLADQTDQTELGG-KLPFALAERLHISRGE
MMAR_1523|M.marinum_M LQRCEVARRRLPSIEHPLINQLVEQAGEQELGG-KLAAVLAGRLRVSRGE
MUL_2371|M.ulcerans_Agy99 LERLEVVARRLPAAQYALVNQLDEQPGEAELGG-RLAAVVASRLRITRSE
MAB_0990c|M.abscessus_ATCC_199 LARLKVVQRRLASRGLGLVSAVTGQASPMQLGGTSYAEVLSRRMHMGKRA
MAV_3664|M.avium_104 LERMEASRRRQIAVSHDVIAGLAGE-GPANVGG-PVHKVIADRLRISYAE
MSMEG_2663|M.smegmatis_MC2_155 CAGIQDVRNLAPAVEHRAIAALSEQTTPAAIGAKSWPLVLATRLGISSKE
TH_3740|M.thermoresistible__bu IRRLEILERRTRAHQQRLLGRLVAESVAGSVAG-----SVGKALRISPAE
. . : : ... :. : :
Mvan_5720|M.vanbaalenii_PYR-1 AKRRIEDAGAVPT-------------------------------------
Mflv_1097|M.gilvum_PYR-GCK AQRRISEAAAPIDS------------------------------------
Mb1728c|M.bovis_AF2122/97 ASRRIHEAADLGPRRTLTGQPLPPLLTATAAAQRAGHLGPAHVQVIRCFL
Rv1702c|M.tuberculosis_H37Rv ASRRIHEAADLGPRRTLTGQPLPPLLTATAAAQRAGHLGPAHVQVIRCFL
MMAR_1523|M.marinum_M ASRRLREAADLGPRRALTGEQLAPLLSATASAVRQGRIGAGHVRVIREFC
MUL_2371|M.ulcerans_Agy99 AGRRVAEAAEVGPRRALSGQPVGPVLTATAAALRQGVVGEGHVRVIRDFF
MAB_0990c|M.abscessus_ATCC_199 ARRRIADAELLAPRRAITGEQLAPQLPHTAQALGRGDIGEEHLRIIRHFF
MAV_3664|M.avium_104 ACRRLREAKQLSPRLTLTGQELPPELPATAGVWREGMLDGQHLRVIEKFV
MSMEG_2663|M.smegmatis_MC2_155 ARRRCADAAELGPRVSLTGEALAPKREHIAAAQADGALTPDHVTELFKFF
TH_3740|M.thermoresistible__bu AHRRITEARGLAS-------------------------------------
* ** :*
Mvan_5720|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1097|M.gilvum_PYR-GCK --------------------------------------------------
Mb1728c|M.bovis_AF2122/97 HQLPHHVDLPTREKAEAELATLGGRFRPDQLHKLATKLADCLNPDG-NYN
Rv1702c|M.tuberculosis_H37Rv HQLPHHVDLPTREKAEAELATLGGRFRPDQLHKLATKLADCLNPDG-NYN
MMAR_1523|M.marinum_M GQVPAEVDLETRERAEAHLARLAGQFRPDQLAKLAQRLMDCVNPDG-RYS
MUL_2371|M.ulcerans_Agy99 RQLPAGVDVGTRDRAEAHLAKLATQFRPDQLARLAGRLMDCLNPDG-RHS
MAB_0990c|M.abscessus_ATCC_199 DRLPVVVDAATREAAEAQLAVMATQFRPEALRVGADRMMALLNPDG-QFS
MAV_3664|M.avium_104 RDLPETTPVRALEEAERFLAHQATLLRPDQLEKVAHQCALRINPDG-KFS
MSMEG_2663|M.smegmatis_MC2_155 TKCPDWVTYAEQCRLEEKLVTGAIGADPETVRQAVDHAVFLLDQDGPAPT
TH_3740|M.thermoresistible__bu --------------------------------------------------
Mvan_5720|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1097|M.gilvum_PYR-GCK --------------------------------------------------
Mb1728c|M.bovis_AF2122/97 DTDRARRRSIILGNQGPDGMSAISGYLTPEARATVDAVLAKLAAPGMANP
Rv1702c|M.tuberculosis_H37Rv DTDRARRRSIILGNQGPDGMSAISGYLTPEARATVDAVLAKLAAPGMANP
MMAR_1523|M.marinum_M DEDRARRRGLTLGRQGRDGMSRISGWLTPEARAGLDAVLAKLAAPGMCNP
MUL_2371|M.ulcerans_Agy99 DEDRARRRGLSLGRQGLDGMSRISGWLTPEARAGLEAVWAKLAAPGMCNP
MAB_0990c|M.abscessus_ATCC_199 DADRARRRGITIGPQGFDGMSAISGLLDPETRAYLDAVFAKLAAPGMCNP
MAV_3664|M.avium_104 DADRARQRGFTWCGQRADEMSLGKLWASPELRANLDAWLARFAAPGMCNP
MSMEG_2663|M.smegmatis_MC2_155 DNPPTKPFGITFGPQQPDGSYHLRGKVSAEFKATFDPIDEKLAAPGMCNP
TH_3740|M.thermoresistible__bu --------------------------------------------------
Mvan_5720|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1097|M.gilvum_PYR-GCK --------------------------------------------------
Mb1728c|M.bovis_AF2122/97 ADDTPCLAGTPSQAAIEADTRSAGQRHHDGLLAALRALLCSGELGQHNGL
Rv1702c|M.tuberculosis_H37Rv ADDTPCLAGTPSQAAIEADTRSAGQRHHDGLLAALRALLCSGELGQHNGL
MMAR_1523|M.marinum_M DDESPVVQAPAGADAVSRDRRSVGQRHHDGLNAAVRALLASGDLGQHNGL
MUL_2371|M.ulcerans_Agy99 EDEAAVVDGPVSRDAADRDSRSVSQRQHDGFNAALRAVLASGELGQHNGL
MAB_0990c|M.abscessus_ATCC_199 NDQSPLVDGQPADDAAERDTRTVAQRHHDALRAALRSTLVSTELGSHHGL
MAV_3664|M.avium_104 DDEVPCVAGEPDEESATKDSRTPAQRQHDALNALVRGRLGDPKLGLHNGL
MSMEG_2663|M.smegmatis_MC2_155 TDQTPCISGTPSQQQIDHDERGAPERRHDAMLTAMRLLLAHKDLGQINGL
TH_3740|M.thermoresistible__bu --------------------------------------------------
Mvan_5720|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1097|M.gilvum_PYR-GCK --------------------------------------------------
Mb1728c|M.bovis_AF2122/97 PAAIIVSTSLTELQSRAGHALTGGGTLLPMSDVIRLASHANHYLRIFD--
Rv1702c|M.tuberculosis_H37Rv PAAIIVSTSLTELQSRAGHALTGGGTLLPMSDVIRLASHANHYLRIFD--
MMAR_1523|M.marinum_M PASIIVTTTLGELQRACGRGLTGGGTVLPISDVIRLARHAHHYLAVFD--
MUL_2371|M.ulcerans_Agy99 PASIIVSTTLKELEAAAGRGLTGGGTLLPMSDVIRLARHAHHYLAVFD--
MAB_0990c|M.abscessus_ATCC_199 PVTVVVTTTLKELEDAAGIAITGAGTRLPMRDLIRMATHAHHYLAIFDD-
MAV_3664|M.avium_104 PVTVIVSTTLRELTTGAGRAVTGGGTLLPMRDVIRMARHAYHYLAVFDEH
MSMEG_2663|M.smegmatis_MC2_155 PATLLITTTLQELEKAAGVAITAGGTKLSIPDLIRLASQALHYLAVYDEH
TH_3740|M.thermoresistible__bu --------------------------------------------------
Mvan_5720|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1097|M.gilvum_PYR-GCK --------------------------------------------------
Mb1728c|M.bovis_AF2122/97 HGRELALYHTKRLASPGQRIVLYAKDRGCSFPNCDVPGYLTEVHHVT-DF
Rv1702c|M.tuberculosis_H37Rv HGRELALYHTKRLASPGQRIVLYAKDRGCSFPNCDVPGYLTEVHHVT-DF
MMAR_1523|M.marinum_M RGKAVGLYHAKRLATAGQRLVLYAKDRGCTRPGCDVPGYQCEVHHVA-AW
MUL_2371|M.ulcerans_Agy99 RGEAIGLYHAKRLATPGQRIVLYAKDRGCTRPGCDVAGYQCEVHHVA-AW
MAB_0990c|M.abscessus_ATCC_199 HGRALYLGRSQRIASPDQRLVLHARDRGCTHPDCHVPGYLCQAHHIT-EW
MAV_3664|M.avium_104 SSRPLYLGRSRRVASPDQRVVLYAKDRGCTHPGCDAPGYWCEVHHLD-EW
MSMEG_2663|M.smegmatis_MC2_155 TGVPLYLGRARRTASAGQRLAIWARDRGCTRPGCTANGYRCQAHHATTDY
TH_3740|M.thermoresistible__bu --------------------------------------------------
Mvan_5720|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1097|M.gilvum_PYR-GCK --------------------------------------------------
Mb1728c|M.bovis_AF2122/97 AQCQETDINELTQGCGPHHQLATTGG--WITRKRKDGTTEWLPPAHLDHG
Rv1702c|M.tuberculosis_H37Rv AQCQETDINELTQGCGPHHQLATTGG--WITRKRKDGTTEWLPPAHLDHG
MMAR_1523|M.marinum_M ATSGRTDIDQLTLACGPDHKLLEQG---WRTRKNAHGDTEWLPPPHLDHG
MUL_2371|M.ulcerans_Agy99 AISGRTDINQLTLACGPDHKLLEQG---WRTRKNAHGDTEWLPPPHLDHG
MAB_0990c|M.abscessus_ATCC_199 VHDGPTDIDNLTFACAPHHRLLGHG---WTTRKRKDGTTEWIPPPQLALP
MAV_3664|M.avium_104 ATGGLTDVDNLTFACGTHHKLIENG---WRTNKLADGRTAWIPPPQWDRG
MSMEG_2663|M.smegmatis_MC2_155 AKGGLTDADALALACGCDNRLVGEAPNKWTTRINNHGQCEWIPPQLLDRG
TH_3740|M.thermoresistible__bu --------------------------------------------------
Mvan_5720|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1097|M.gilvum_PYR-GCK --------------------------------------------------
Mb1728c|M.bovis_AF2122/97 QPRTNSYFHPEKLLHDSDEDDP----------------------------
Rv1702c|M.tuberculosis_H37Rv QPRTNSYFHPEKLLHDSDEDDP----------------------------
MMAR_1523|M.marinum_M QPRTNTYHHPEKLLRDSAADEGEEGG------------------------
MUL_2371|M.ulcerans_Agy99 QPRTNSYHHPEKLLRDSADDDDEGHGAA----------------------
MAB_0990c|M.abscessus_ATCC_199 G-ETRHDDIVDQCPHGVGSR------------------------------
MAV_3664|M.avium_104 A-RTNEFHHPERAFDGEDP-------------------------------
MSMEG_2663|M.smegmatis_MC2_155 QHRTNTYHHPETLLADIKSGFTDDTADSRSQTSKTTGSETHAKQAADTEP
TH_3740|M.thermoresistible__bu --------------------------------------------------
Mvan_5720|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1097|M.gilvum_PYR-GCK --------------------------------------------------
Mb1728c|M.bovis_AF2122/97 --------------------------------------------------
Rv1702c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1523|M.marinum_M --------------------------------------------------
MUL_2371|M.ulcerans_Agy99 --------------------------------------------------
MAB_0990c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_3664|M.avium_104 --------------------------------------------------
MSMEG_2663|M.smegmatis_MC2_155 DTAIARGNDLSDRPAIPPELLGQNHQQPNTNHHPDTERGDARNSGATGHN
TH_3740|M.thermoresistible__bu --------------------------------------------------
Mvan_5720|M.vanbaalenii_PYR-1 -----------------------------------
Mflv_1097|M.gilvum_PYR-GCK -----------------------------------
Mb1728c|M.bovis_AF2122/97 -----------------------------------
Rv1702c|M.tuberculosis_H37Rv -----------------------------------
MMAR_1523|M.marinum_M -----------------------------------
MUL_2371|M.ulcerans_Agy99 -----------------------------------
MAB_0990c|M.abscessus_ATCC_199 -----------------------------------
MAV_3664|M.avium_104 -----------------------------------
MSMEG_2663|M.smegmatis_MC2_155 QDHSRKNGDRNSGDASKGNNGNADGDDGESDCHPA
TH_3740|M.thermoresistible__bu -----------------------------------