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MHSIEVPAEVRAALDALDTADAAIRALDFDALHPVVRLRALERMEASRRRQIAVSHDVIAGLAGEGPANV GGPVHKVIADRLRISYAEACRRLREAKQLSPRLTLTGQELPPELPATAGVWREGMLDGQHLRVIEKFVRD LPETTPVRALEEAERFLAHQATLLRPDQLEKVAHQCALRINPDGKFSDADRARQRGFTWCGQRADEMSLG KLWASPELRANLDAWLARFAAPGMCNPDDEVPCVAGEPDEESATKDSRTPAQRQHDALNALVRGRLGDPK LGLHNGLPVTVIVSTTLRELTTGAGRAVTGGGTLLPMRDVIRMARHAYHYLAVFDEHSSRPLYLGRSRRV ASPDQRVVLYAKDRGCTHPGCDAPGYWCEVHHLDEWATGGLTDVDNLTFACGTHHKLIENGWRTNKLADG RTAWIPPPQWDRGARTNEFHHPERAFDGEDP
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. avium 104 | MAV_3664 | - | - | 100% (451) | hypothetical protein MAV_3664 |
M. avium 104 | MAV_2352 | - | e-127 | 52.58% (445) | hypothetical protein MAV_2352 |
M. avium 104 | MAV_2806 | - | e-120 | 49.78% (452) | hypothetical protein MAV_2806 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1159c | - | 1e-116 | 49.44% (447) | hypothetical protein Mb1159c |
M. gilvum PYR-GCK | Mflv_1835 | - | 4e-88 | 43.21% (449) | hypothetical protein Mflv_1835 |
M. tuberculosis H37Rv | Rv1128c | - | 1e-117 | 49.44% (447) | hypothetical protein Rv1128c |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_0394c | - | 1e-118 | 51.15% (434) | hypothetical protein MAB_0394c |
M. marinum M | MMAR_1937 | - | 0.0 | 74.43% (442) | hypothetical protein MMAR_1937 |
M. smegmatis MC2 155 | MSMEG_2663 | - | 6e-79 | 39.41% (444) | hypothetical protein MSMEG_2663 |
M. thermoresistible (build 8) | TH_3287 | - | 2e-76 | 39.58% (480) | PUTATIVE conserved hypothetical protein |
M. ulcerans Agy99 | MUL_2371 | - | 1e-120 | 51.49% (437) | hypothetical protein MUL_2371 |
M. vanbaalenii PYR-1 | Mvan_3050 | - | 1e-100 | 44.17% (480) | hypothetical protein Mvan_3050 |
CLUSTAL 2.0.9 multiple sequence alignment Mb1159c|M.bovis_AF2122/97 -------MCSTREEITEAFASLATALSRVLGLTFDALTTPERLALLEHCE Rv1128c|M.tuberculosis_H37Rv -------MCSTREEITEAFASLATALSRVLGLTFDALTTPERLALLEHCE MUL_2371|M.ulcerans_Agy99 ---MHSNGCSDRESVVATLDRLDRAVDALVEVSFEALTTPERLRVLERLE MAB_0394c|M.abscessus_ATCC_199 ---------------MSPIDDLLTTATAVVESSFDELNNPELLSALRQLE Mflv_1835|M.gilvum_PYR-GCK ----MYVRVMSGGDLQTRIAVLRAAFDEVAACEIELLTRPDLVAALDELE MSMEG_2663|M.smegmatis_MC2_155 -MIRTSVRYMAA-EVGTALAALHAAMRDVLALPYTALSDADLLDVCAGIQ Mvan_3050|M.vanbaalenii_PYR-1 -------MGCSREDVLGAFDALDAVVESILALDYDALSAAERVRLEARLE MAV_3664|M.avium_104 -----MHSIEVPAEVRAALDALDTADAAIRALDFDALHPVVRLRALERME MMAR_1937|M.marinum_M -----MYSIS------ALLDALDAAVAAIGEADLGHLEPAARLRALQRLE TH_3287|M.thermoresistible__bu MGQQFVTAGAARARVGELLAAVDAAYAEMRALCLDEVGTGFRLELAERLE : : . : : : : Mb1159c|M.bovis_AF2122/97 TARRQLPSVEHTLINQIGEQSTEEELGG-KLGLTLADRLRITRSEAKRRV Rv1128c|M.tuberculosis_H37Rv TARRQLPSVEHTLINQIGEQSTEEELGG-KLGLTLADRLRITRSEAKRRV MUL_2371|M.ulcerans_Agy99 VVARRLPAAQYALVNQLDEQPGEAELGG-RLAAVVASRLRITRSEAGRRV MAB_0394c|M.abscessus_ATCC_199 IAQRKITAASHTLTARLVQRGSPVALGGTSFAEVLARYLSITTATARRRL Mflv_1835|M.gilvum_PYR-GCK ELSCQLPAVGHRLLARLQAEGTPQQMGAKNWSEVLRVRWRISGSEAHRRL MSMEG_2663|M.smegmatis_MC2_155 DVRNLAPAVEHRAIAALSEQTTPAAIGAKSWPLVLATRLGISSKEARRRC Mvan_3050|M.vanbaalenii_PYR-1 RNLRRIPTVEHELLASVIAETEPARLGEGSWKKVLTTALRISGAEAGRRL MAV_3664|M.avium_104 ASRRRQIAVSHDVIAGLAGE-GPANVGG-PVHKVIADRLRISYAEACRRL MMAR_1937|M.marinum_M NARRRQAVVSHDVIAGLATE-DLADIGG-PVYKVVADWLRISCAEARRRV TH_3287|M.thermoresistible__bu TQCRINRGLMYRVFAQLADPPDEPAMVP-AVRDRLWARLRITPGEVKRRL : : : : *: . ** Mb1159c|M.bovis_AF2122/97 AEAADLGQRRALTGEPLPPLLTATAKAQRHGLIGDGHVEVIRAFVHRLPS Rv1128c|M.tuberculosis_H37Rv AEAADLGQRRALTGEPLPPLLTATAKAQRHGLIGDGHVEVIRAFVHRLPS MUL_2371|M.ulcerans_Agy99 AEAAEVGPRRALSGQPVGPVLTATAAALRQGVVGEGHVRVIRDFFRQLPA MAB_0394c|M.abscessus_ATCC_199 ADAAHLGPRRALTGEPLRPALPYVAHALREGRLGDEHVRIIRRFFDVLPD Mflv_1835|M.gilvum_PYR-GCK TEAALLAPRPSLTGPALPPQLAATAIAQARGLINAEHVAVIRKAVKKLPG MSMEG_2663|M.smegmatis_MC2_155 ADAAELGPRVSLTGEALAPKREHIAAAQADGALTPDHVTELFKFFTKCPD Mvan_3050|M.vanbaalenii_PYR-1 KRAKTLGPRRGLTGTPLPPLWESTAAAQAQGLLSEEHVAVIAAFHKRLPA MAV_3664|M.avium_104 REAKQLSPRLTLTGQELPPELPATAGVWREGMLDGQHLRVIEKFVRDLPE MMAR_1937|M.marinum_M HDAQQLSPRITLTGQPLPAELPATAQVWRRGLLDGQHVKVIAAFVRDLPQ TH_3287|M.thermoresistible__bu RVAALLRPRRRLSGPPLPPVLARVAGAVESGLLGEEHLRVITTVMAALPS * : * *:* : . * . * : *: : * Mb1159c|M.bovis_AF2122/97 WVDLKTLEKAERDLAKQATQYRPDQLAKLAARIMDCLNPDG-DYTDEDRA Rv1128c|M.tuberculosis_H37Rv WVDLKTLEKAERDLAKQATQYRPDQLAKLAARIMDCLNPDG-DYTDEDRA MUL_2371|M.ulcerans_Agy99 GVDVGTRDRAEAHLAKLATQFRPDQLARLAGRLMDCLNPDG-RHSDEDRA MAB_0394c|M.abscessus_ATCC_199 AVDADTREAAEKQLASMGTEFGPEQLRAGADRIAALVNPDG-RFSDIDRA Mflv_1835|M.gilvum_PYR-GCK WVDVATREQFEVNLVRTAVGHGPKELNDAADRMLFLLDQDGPEPDDAERG MSMEG_2663|M.smegmatis_MC2_155 WVTYAEQCRLEEKLVTGAIGADPETVRQAVDHAVFLLDQDGPAPTDNPPT Mvan_3050|M.vanbaalenii_PYR-1 WVDIETRAEADRQLAHAGSGLDPEGLDEAAGVLLAMINPDGAQPCDKERA MAV_3664|M.avium_104 TTPVRALEEAERFLAHQATLLRPDQLEKVAHQCALRINPDG-KFSDADRA MMAR_1937|M.marinum_M DTPADTVRQAEQFLARQAVQLRPDQLEKVANRAAVLINPDG-KFSDADRA TH_3287|M.thermoresistible__bu AVSVTDREAVEASLIAEAARSDAGIVRQVGRRIEEIFNPDG-HYDDQDRA . : * . . : .: ** * Mb1159c|M.bovis_AF2122/97 RRRGLTLGKQDVDGMSRLSGYVTPELRATIEAVWAKLAAPGMCNPEQKA- Rv1128c|M.tuberculosis_H37Rv RRRGLTLGKQDVDGMSRLSGYVTPELRATIEAVWAKLAAPGMCNPEQKA- MUL_2371|M.ulcerans_Agy99 RRRGLSLGRQGLDGMSRISGWLTPEARAGLEAVWAKLAAPGMCNPEDEA- MAB_0394c|M.abscessus_ATCC_199 RRRGISIGRQGADGMSALSGLLDPETRAYFDAVLSKLAAPGMCDPRDES- Mflv_1835|M.gilvum_PYR-GCK RKRGVSIGRQGAEAMSALTGQLTPEARAVWEAIFAKYAAPGMCNPDDEQ- MSMEG_2663|M.smegmatis_MC2_155 KPFGITFGPQQPDGSYHLRGKVSAEFKATFDPIDEKLAAPGMCNPTDQT- Mvan_3050|M.vanbaalenii_PYR-1 RKRGIRISKQHPDGTATISGTLTPEALAIWQAIFAKEAAPGANNPESEHT MAV_3664|M.avium_104 RQRGFTWCGQRADEMSLGKLWASPELRANLDAWLARFAAPGMCNPDD--- MMAR_1937|M.marinum_M RQRGFTWCAQRPDGMSIGKLIATPQLRAHLDAWLARFAAPGMCNPDD--- TH_3287|M.thermoresistible__bu RRRGIHLGDQQRDGMSAISGWIDPQLRAYLEAVTAAVR-PGRHLPHTTTD : *. * : .: * :. ** * Mb1159c|M.bovis_AF2122/97 ----------PCVNG------------------------------APSKE Rv1128c|M.tuberculosis_H37Rv ----------PCVNG------------------------------APSKE MUL_2371|M.ulcerans_Agy99 ----------AVVDG------------------------------PVSRD MAB_0394c|M.abscessus_ATCC_199 ----------PMTEG------------------------------EPDSA Mflv_1835|M.gilvum_PYR-GCK ----------PCTSG------------------------------TPSQA MSMEG_2663|M.smegmatis_MC2_155 ----------PCISG------------------------------TPSQQ Mvan_3050|M.vanbaalenii_PYR-1 ---------EDSTSGGAADDASDAPGDHAGAASSAASGASDAAEHDPQPE MAV_3664|M.avium_104 --------EVPCVAG------------------------------EPDEE MMAR_1937|M.marinum_M --------ETPCVKG------------------------------EPTDE TH_3287|M.thermoresistible__bu TTGTTGTTETTGTAG------------------------------TAGTA * Mb1159c|M.bovis_AF2122/97 QARRD---------------TRSCPQRNHDALNAGLRSLLTSGNLGQHNG Rv1128c|M.tuberculosis_H37Rv QARRD---------------TRSCPQRNHDALNAELRSLLTSGNLGQHNG MUL_2371|M.ulcerans_Agy99 AADRD---------------SRSVSQRQHDGFNAALRAVLASGELGQHNG MAB_0394c|M.abscessus_ATCC_199 AAERD---------------TRTSAQRNHDGLRACLRSTLASGKLGAHRG Mflv_1835|M.gilvum_PYR-GCK QIDGD---------------HRSLAQRQHDALLAVGRIALMSGELGQLNG MSMEG_2663|M.smegmatis_MC2_155 QIDHD---------------ERGAPERRHDAMLTAMRLLLAHKDLGQING Mvan_3050|M.vanbaalenii_PYR-1 RCGSD---------------TRTQAQRNHDAFLAVGRRLLESGELGTHNG MAV_3664|M.avium_104 SATKD---------------SRTPAQRQHDALNALVRGRLGDPKLGLHNG MMAR_1937|M.marinum_M VTAKD---------------LRSPAQRRHDALNALLDGRLGDPKLGAHNG TH_3287|M.thermoresistible__bu ATAADTAADGVGDIDTGGVDLRSAAQRRHDGLTLGLKIAVASGRLGSHRG * * .:*.**.: : ** .* Mb1159c|M.bovis_AF2122/97 LPASIIVTTTLKDLEAAA-----------GAGLTGGGTILPISDVIRLAR Rv1128c|M.tuberculosis_H37Rv LPASIIVTTTLKDLEAAA-----------GAGLTGGGTILPISDVIRLAR MUL_2371|M.ulcerans_Agy99 LPASIIVSTTLKELEAAA-----------GRGLTGGGTLLPMSDVIRLAR MAB_0394c|M.abscessus_ATCC_199 LPVTVVVSTTLRELQSAA-----------GRAISGSGNLVPIPDLIRMAT Mflv_1835|M.gilvum_PYR-GCK LPVSVIIRTTLQDLESRA-----------GIGVSGGGTKLPIRDVIRMAG MSMEG_2663|M.smegmatis_MC2_155 LPATLLITTTLQELEKAA-----------GVAITAGGTKLSIPDLIRLAS Mvan_3050|M.vanbaalenii_PYR-1 LPVTVIVSTTLQELEKGA-----------GVAVTGGGSLLPMPDLIRLAA MAV_3664|M.avium_104 LPVTVIVSTTLRELTTGA-----------GRAVTGGGTLLPMRDVIRMAR MMAR_1937|M.marinum_M LPVTVIVSTTLRELTSGT-----------GRAVTGGGTFVPMRDVIRMAS TH_3287|M.thermoresistible__bu HPVTVIVRTTLGELNQAAHAVADPRVSMPGPARTGGTGVLPMRELIRMAA *.:::: *** :* : * . :.. :.: ::**:* Mb1159c|M.bovis_AF2122/97 HANHYLAIF--DRGKALALYHTKRLASPAQRIMLYAKDSGCSAPGCDVPG Rv1128c|M.tuberculosis_H37Rv HANHYLAIF--DRGKALALYHTKRLASPAQRIMLYAKDSGCSAPGCDVPG MUL_2371|M.ulcerans_Agy99 HAHHYLAVF--DRGEAIGLYHAKRLATPGQRIVLYAKDRGCTRPGCDVAG MAB_0394c|M.abscessus_ATCC_199 HAFHYLTIFG-DDGRPLHLGRSKRIATPDQRIVLHAKDRGCSAPGCTVPG Mflv_1835|M.gilvum_PYR-GCK HANHYLAVFDRATGSALDLFRTRRVASPAQRVMLIARDGGCTKPCCTVGA MSMEG_2663|M.smegmatis_MC2_155 QALHYLAVYDEHTGVPLYLGRARRTASAGQRLAIWARDRGCTRPGCTANG Mvan_3050|M.vanbaalenii_PYR-1 RAHHYLYVYDQHSGKSLYLGRAKRLANAAQRIVLHARDRGCTRPGCTAPG MAV_3664|M.avium_104 HAYHYLAVFDEHSSRPLYLGRSRRVASPDQRVVLYAKDRGCTHPGCDAPG MMAR_1937|M.marinum_M RAYHYLAVFDEHSNRPLYLGRSRRLASADQRLVLYAQDRGCTHPGCDVPG TH_3287|M.thermoresistible__bu DAIHYLAVFDDHTERPLYLGRQKRIATADQRLICYARDGGCTAPGCGEPG * *** :: .: * : :* *.. **: *:* **: * * . Mb1159c|M.bovis_AF2122/97 YYCEVHHVTP-YAQCRNTDVNDLTLGCGGHHP-LAERG--WTTRKN-AHG Rv1128c|M.tuberculosis_H37Rv YYCEVHHVTP-YAQCRNTDVNDLTLGCGGHHP-LAERG--WTTRKN-AHG MUL_2371|M.ulcerans_Agy99 YQCEVHHVAA-WAISGRTDINQLTLACGPDHK-LLEQG--WRTRKN-AHG MAB_0394c|M.abscessus_ATCC_199 YLCQVHHVDD-WRDDGPTDIDNLTFACGPHHR-LLQQG--WTTRKRRSDG Mflv_1835|M.gilvum_PYR-GCK YGCQVHHAEADYAHGGNTNIDELGLACGPDNRSVTDGG--WTTRMN-DRC MSMEG_2663|M.smegmatis_MC2_155 YRCQAHHATTDYAKGGLTDADALALACGCDNRLVGEAPNKWTTRIN-NHG Mvan_3050|M.vanbaalenii_PYR-1 YWCQAHHASADFVDGGLTNIDDLTLACPCDHRMLDNTG--WRTRKN-GKN MAV_3664|M.avium_104 YWCEVHHLDE-WATGGLTDVDNLTFACGTHHK-LIENG--WRTNKL-ADG MMAR_1937|M.marinum_M YWCEVHHTDE-WAAGGPTDVDKLTFACKPDHK-LAGNG--WQTTKL-PNG TH_3287|M.thermoresistible__bu YHAETHHQPA-WEDGGLTDADHLFFACGPHHSGLTEGR--WQATIT-PTG * .:.** : *: : * :.* .: : * : Mb1159c|M.bovis_AF2122/97 DTEWLPPPHLDHGQPRVNTFHHPEKLLAD--------------------- Rv1128c|M.tuberculosis_H37Rv DTEWLPPPHLDHGQPRVNTFHHPEKLLAD--------------------- MUL_2371|M.ulcerans_Agy99 DTEWLPPPHLDHGQPRTNSYHHPEKLLRDSA------------------- MAB_0394c|M.abscessus_ATCC_199 ITEWIPPPHLDTGQSRTNDHHHPERFIRRF-------------------- Mflv_1835|M.gilvum_PYR-GCK EVEWIPPPGLDTGQARVNTYHRPERLLRPED------------------- MSMEG_2663|M.smegmatis_MC2_155 QCEWIPPQLLDRGQHRTNTYHHPETLLADIKSGFTDDTADSRSQTSKTTG Mvan_3050|M.vanbaalenii_PYR-1 QTEWLPPPDLDTGQHRVNGHHHPERYLLPED------------------- MAV_3664|M.avium_104 RTAWIPPPQWDRGAR-TNEFHHPERAFDG--------------------- MMAR_1937|M.marinum_M RTAWIPPPQLDRGAR-TNDYHHPERLFDD--------------------- TH_3287|M.thermoresistible__bu RLAWTND---HHPPT-VNHAHHPEELLRAHT------------------- * . .* *:** : Mb1159c|M.bovis_AF2122/97 ----------------------------------DEGDP----------- Rv1128c|M.tuberculosis_H37Rv ----------------------------------DEGDP----------- MUL_2371|M.ulcerans_Agy99 -------------------------------DDDDEGHGAA--------- MAB_0394c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_1835|M.gilvum_PYR-GCK ------------------------------PEPLGDNDSQ---------- MSMEG_2663|M.smegmatis_MC2_155 SETHAKQAADTEPDTAIARGNDLSDRPAIPPELLGQNHQQPNTNHHPDTE Mvan_3050|M.vanbaalenii_PYR-1 --------------------------------DLPEDDQGP--------- MAV_3664|M.avium_104 -----------------------------------EDP------------ MMAR_1937|M.marinum_M -----------------------------------EGP------------ TH_3287|M.thermoresistible__bu --------------------------------DPPEDPG----------- Mb1159c|M.bovis_AF2122/97 ------------------------------------------------ Rv1128c|M.tuberculosis_H37Rv ------------------------------------------------ MUL_2371|M.ulcerans_Agy99 ------------------------------------------------ MAB_0394c|M.abscessus_ATCC_199 ------------------------------------------------ Mflv_1835|M.gilvum_PYR-GCK ---------------ASRPADD-------PGEPGGPAPPEGEAA---- MSMEG_2663|M.smegmatis_MC2_155 RGDARNSGATGHNQDHSRKNGDRNSGDASKGNNGNADGDDGESDCHPA Mvan_3050|M.vanbaalenii_PYR-1 ------------------------------------------------ MAV_3664|M.avium_104 ------------------------------------------------ MMAR_1937|M.marinum_M ------------------------------------------------ TH_3287|M.thermoresistible__bu ------------------------------------------------