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SSIGVVEAAVDAFCAESIEDLTAGEALAMLARLKVVQRRLASRGLGLVSAVTGQASPMQLGGTSYAEVLS RRMHMGKRAARRRIADAELLAPRRAITGEQLAPQLPHTAQALGRGDIGEEHLRIIRHFFDRLPVVVDAAT REAAEAQLAVMATQFRPEALRVGADRMMALLNPDGQFSDADRARRRGITIGPQGFDGMSAISGLLDPETR AYLDAVFAKLAAPGMCNPNDQSPLVDGQPADDAAERDTRTVAQRHHDALRAALRSTLVSTELGSHHGLPV TVVVTTTLKELEDAAGIAITGAGTRLPMRDLIRMATHAHHYLAIFDDHGRALYLGRSQRIASPDQRLVLH ARDRGCTHPDCHVPGYLCQAHHITEWVHDGPTDIDNLTFACAPHHRLLGHGWTTRKRKDGTTEWIPPPQL ALPGETRHDDIVDQCPHGVGSR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0990c | - | - | 100% (443) | hypothetical protein MAB_0990c |
| M. abscessus ATCC 19977 | MAB_0394c | - | e-154 | 62.50% (432) | hypothetical protein MAB_0394c |
| M. abscessus ATCC 19977 | MAB_2374c | - | e-115 | 52.06% (413) | hypothetical protein MAB_2374c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1179c | - | 1e-119 | 53.55% (422) | hypothetical protein Mb1179c |
| M. gilvum PYR-GCK | Mflv_4014 | - | 1e-100 | 46.57% (423) | hypothetical protein Mflv_4014 |
| M. tuberculosis H37Rv | Rv1148c | - | 1e-119 | 53.55% (422) | hypothetical protein Rv1148c |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_3121 | - | 1e-126 | 53.68% (421) | hypothetical protein MMAR_3121 |
| M. avium 104 | MAV_2352 | - | 1e-122 | 52.97% (421) | hypothetical protein MAV_2352 |
| M. smegmatis MC2 155 | MSMEG_6573 | - | 1e-84 | 41.18% (425) | hypothetical protein MSMEG_6573 |
| M. thermoresistible (build 8) | TH_3287 | - | 3e-73 | 40.35% (456) | PUTATIVE conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_2371 | - | 1e-126 | 53.44% (421) | hypothetical protein MUL_2371 |
| M. vanbaalenii PYR-1 | Mvan_3050 | - | 2e-96 | 43.76% (457) | hypothetical protein Mvan_3050 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1179c|M.bovis_AF2122/97 MSETFCLTDHSEPMTARFLSVVLRRIRGMRSDTREEISAALDAYHAS---
Rv1148c|M.tuberculosis_H37Rv MSETFCLTDHSEPMTARFLSVVLRRIRGMRSDTREEISAALDAYHAS---
MMAR_3121|M.marinum_M -------------------------MHSNGCSDRESVVATLDRLDRA---
MUL_2371|M.ulcerans_Agy99 -------------------------MHSNGCSDRESVVATLDRLDRA---
MAV_2352|M.avium_104 -------------------------MHS---STREEIRADVDALRAA---
MAB_0990c|M.abscessus_ATCC_199 -------------------------------------MSSIGVVEAA---
Mflv_4014|M.gilvum_PYR-GCK --------------------------MAGLSVGRTSVRCMDGVAEAVGVI
Mvan_3050|M.vanbaalenii_PYR-1 -----------------------------MGCSREDVLGAFDALDAV---
MSMEG_6573|M.smegmatis_MC2_155 --------------------------------MDDGVQDAVAALDAA---
TH_3287|M.thermoresistible__bu ----------------------MGQQFVTAGAARARVGELLAAVDAA---
Mb1179c|M.bovis_AF2122/97 --LSRVLDLKCDALTTPELLACLQRLEVERRRQGAAEHALINQLAGQACE
Rv1148c|M.tuberculosis_H37Rv --LSRVLDLKCDALTTPELLACLQRLEVERRRQGAAEHALINQLAGQACE
MMAR_3121|M.marinum_M --VDALVEVSFEALTTPERLRVLERLEVVARRLPVAQYALLNQLDEQAGE
MUL_2371|M.ulcerans_Agy99 --VDALVEVSFEALTTPERLRVLERLEVVARRLPAAQYALVNQLDEQPGE
MAV_2352|M.avium_104 --VSRVLGHSYDALTTPERLRLLEIFDRETRRLRVPGHQLINQLAEQSDP
MAB_0990c|M.abscessus_ATCC_199 --VDAFCAESIEDLTAGEALAMLARLKVVQRRLASRGLGLVSAVTGQASP
Mflv_4014|M.gilvum_PYR-GCK GEQLAVLAKAAEDLSHRELIGLLSELTTVLRSAPAVEHAVLARLLDETEP
Mvan_3050|M.vanbaalenii_PYR-1 --VESILALDYDALSAAERVRLEARLERNLRRIPTVEHELLASVIAETEP
MSMEG_6573|M.smegmatis_MC2_155 --LNTLLTLPHSALTDAELLTICAGLQDARNRIPAVEHRAIAALSQQTTP
TH_3287|M.thermoresistible__bu --YAEMRALCLDEVGTGFRLELAERLETQCRINRGLMYRVFAQLADPPDE
. . : : : . . : .
Mb1179c|M.bovis_AF2122/97 EELGGT-LRTALANRLHITPGEASRRIAEAEDLGERRALTGEPLPAQLTA
Rv1148c|M.tuberculosis_H37Rv EELGGT-LRTALANRLHITPGEASRRIAEAEDLGERRALTGEPLPAQLTA
MMAR_3121|M.marinum_M AELGGR-LAAVVASRLRITRSEAGRRVAEAADVGPRRALSGQPVGPVLTA
MUL_2371|M.ulcerans_Agy99 AELGGR-LAAVVASRLRITRSEAGRRVAEAAEVGPRRALSGQPVGPVLTA
MAV_2352|M.avium_104 TELGGR-LSFALAERLHITRSDASRRIAEAADLGPRRALTGEPLPPLLPA
MAB_0990c|M.abscessus_ATCC_199 MQLGGTSYAEVLSRRMHMGKRAARRRIADAELLAPRRAITGEQLAPQLPH
Mflv_4014|M.gilvum_PYR-GCK HHLGEASWKKVLTTSLRMSSAEAGRRLQRAKNLGPRRAMTGEPLAPVWES
Mvan_3050|M.vanbaalenii_PYR-1 ARLGEGSWKKVLTTALRISGAEAGRRLKRAKTLGPRRGLTGTPLPPLWES
MSMEG_6573|M.smegmatis_MC2_155 AAIGAKSWPLVLATRLGISSKEARRRCTDAAELGPRVSMTGEALAPKREH
TH_3287|M.thermoresistible__bu PAMVPA-VRDRLWARLRITPGEVKRRLRVAALLRPRRRLSGPPLPPVLAR
: : : : . ** * : * ::* : .
Mb1179c|M.bovis_AF2122/97 TAAAQREGKIGREHIKEIQAFFKELSAAVDLGIREAAEAQLAELATSRRP
Rv1148c|M.tuberculosis_H37Rv TAAAQREGKIGREHIKEIQAFFKELSAAVDLGIREAAEAQLAELATSRRP
MMAR_3121|M.marinum_M TAAALRQGVVGEGHVRVIRDFFRRLPAGVDVGTRDRAEAHLAKLATQFRP
MUL_2371|M.ulcerans_Agy99 TAAALRQGVVGEGHVRVIRDFFRQLPAGVDVGTRDRAEAHLAKLATQFRP
MAV_2352|M.avium_104 TAAAQRDGAIGTDHVAVIRQFFDQLPEAVDVETCEHAERQLAAQATQFRP
MAB_0990c|M.abscessus_ATCC_199 TAQALGRGDIGEEHLRIIRHFFDRLPVVVDAATREAAEAQLAVMATQFRP
Mflv_4014|M.gilvum_PYR-GCK TAAAQAQGHLGEEHVEIIAKFHKKLPSWVDVDTRAAADAQLAHTGSGLGP
Mvan_3050|M.vanbaalenii_PYR-1 TAAAQAQGLLSEEHVAVIAAFHKRLPAWVDIETRAEADRQLAHAGSGLDP
MSMEG_6573|M.smegmatis_MC2_155 IAAAQADGTLTPDHVAELFKFFTKCPDWVTYAEQCRLEEKLVTGAIGADP
TH_3287|M.thermoresistible__bu VAGAVESGLLGEEHLRVITTVMAALPSAVSVTDREAVEASLIAEAARSDA
* * * : *: : . . * : * . .
Mb1179c|M.bovis_AF2122/97 DHLHGLATQLMDWLHPDG-NFSDQERARKRGITMGKQEFDGMSRISGLLT
Rv1148c|M.tuberculosis_H37Rv DHLHGLATQLMDWLHPDG-NFSDQERARKRGITMGKQEFDGMSRISGLLT
MMAR_3121|M.marinum_M DQLARLAGRLMDCLNPDG-RHSDEDRARRRGLSLGRQGLDGMSRISGWLT
MUL_2371|M.ulcerans_Agy99 DQLARLAGRLMDCLNPDG-RHSDEDRARRRGLSLGRQGLDGMSRISGWLT
MAV_2352|M.avium_104 DQLSKLARRLMDCLNPDG-RYSDEDRARARGLVLGNQQADGMSRLSGWLT
MAB_0990c|M.abscessus_ATCC_199 EALRVGADRMMALLNPDG-QFSDADRARRRGITIGPQGFDGMSAISGLLD
Mflv_4014|M.gilvum_PYR-GCK EELAQVADRLLMMIDQDGPEPSEKEKATRFWVKLGTQQRDGGRTISGYVD
Mvan_3050|M.vanbaalenii_PYR-1 EGLDEAAGVLLAMINPDGAQPCDKERARKRGIRISKQHPDGTATISGTLT
MSMEG_6573|M.smegmatis_MC2_155 ETVRQAVDHAVFLLDQDGPAPTDNPPTKPFGITFGPQQPDGSYHLRGKVS
TH_3287|M.thermoresistible__bu GIVRQVGRRIEEIFNPDG-HYDDQDRARRRGIHLGDQQRDGMSAISGWID
: :. ** : : : :. * ** : * :
Mb1179c|M.bovis_AF2122/97 PELRATIEAVLAKLAAPGACNPDDQTPLVDD-------------------
Rv1148c|M.tuberculosis_H37Rv PELRATIEAVLAKLAAPGACNPDDQTPLVDD-------------------
MMAR_3121|M.marinum_M PEARAGLEAVWAKLAAPGMCNPEDEAAVVDG-------------------
MUL_2371|M.ulcerans_Agy99 PEARAGLEAVWAKLAAPGMCNPEDEAAVVDG-------------------
MAV_2352|M.avium_104 PEARAGWEAVLAKLAAPGMCNPDDDAPVVDG-------------------
MAB_0990c|M.abscessus_ATCC_199 PETRAYLDAVFAKLAAPGMCNPNDQSPLVDG-------------------
Mflv_4014|M.gilvum_PYR-GCK AETSAYWEAVLAKEAAPGANMAEQ--------------------------
Mvan_3050|M.vanbaalenii_PYR-1 PEALAIWQAIFAKEAAPGANNPESEHTEDSTSGGAADDASDAPGDHAGAA
MSMEG_6573|M.smegmatis_MC2_155 AEFKATFDPIDEKLAAPGMCNPTDQTPCISG-------------------
TH_3287|M.thermoresistible__bu PQLRAYLEAVTAAVR-PGRHLPHTTTDTTGTTG------TTETTGTAGTA
.: * :.: ** .
Mb1179c|M.bovis_AF2122/97 -------------TPDADAVRRDTRSQAQRNHDAFLAALRGLLASGELGQ
Rv1148c|M.tuberculosis_H37Rv -------------TPDADAVRRDTRSQAQRNHDAFLAALRGLLASGELGQ
MMAR_3121|M.marinum_M -------------PVSPDAADRDSRSVGQRQHDGFNAALRAVLASGELGQ
MUL_2371|M.ulcerans_Agy99 -------------PVSRDAADRDSRSVSQRQHDGFNAALRAVLASGELGQ
MAV_2352|M.avium_104 -------------PPPEAASQRDSRSAAQRNHDGLNAALRALLAGGKLGQ
MAB_0990c|M.abscessus_ATCC_199 -------------QPADDAAERDTRTVAQRHHDALRAALRSTLVSTELGS
Mflv_4014|M.gilvum_PYR-GCK -----------------EKAG-DTRTQGQRNHDGLKAVLRRTLESGQLGS
Mvan_3050|M.vanbaalenii_PYR-1 SSAASGASDAAEHDPQPERCGSDTRTQAQRNHDAFLAVGRRLLESGELGT
MSMEG_6573|M.smegmatis_MC2_155 -------------TPSQQQIDSDQRGAPERRHDAMLTAMRLLLAHKDLGQ
TH_3287|M.thermoresistible__bu GTAATAADTAADGVGDIDTGGVDLRSAAQRRHDGLTLGLKIAVASGRLGS
* * :*.**.: : : **
Mb1179c|M.bovis_AF2122/97 HKGLPVTIVVSTTLKELEAAT-----------GKGVTGGGSRVPMSDLIR
Rv1148c|M.tuberculosis_H37Rv HKGLPVTIVVSTTLKELEAAT-----------GKGVTGGGSRVPMSDLIR
MMAR_3121|M.marinum_M HNGLPASIIVSTTLKELEAAA-----------GRGLTGGGTLLPMSDVIR
MUL_2371|M.ulcerans_Agy99 HNGLPASIIVSTTLKELEAAA-----------GRGLTGGGTLLPMSDVIR
MAV_2352|M.avium_104 HNGLPASIIVTTTLRDLESAA-----------GKGLTGGGTLLPMSEVIR
MAB_0990c|M.abscessus_ATCC_199 HHGLPVTVVVTTTLKELEDAA-----------GIAITGAGTRLPMRDLIR
Mflv_4014|M.gilvum_PYR-GCK HNGLPVTVIVSTTLQELEKGA-----------GVAVTGGGSLLPIPELIR
Mvan_3050|M.vanbaalenii_PYR-1 HNGLPVTVIVSTTLQELEKGA-----------GVAVTGGGSLLPMPDLIR
MSMEG_6573|M.smegmatis_MC2_155 INGLPATLLVTTTLQELEKAA-----------GVAITAGGTKLSIPDLIR
TH_3287|M.thermoresistible__bu HRGHPVTVIVRTTLGELNQAAHAVADPRVSMPGPARTGGTGVLPMRELIR
.* *.:::* *** :*: .: * . *.. :.: ::**
Mb1179c|M.bovis_AF2122/97 MASHANHYLALFD--GAKPLALYHTKRLASPAQRIMLYAKDRGCSRPGCD
Rv1148c|M.tuberculosis_H37Rv MASHANHYLALFD--GAKPLALYHTKRLASPAQRIMLYAKDRGCSRPGCD
MMAR_3121|M.marinum_M LARHAHHYLAVFD--RGEAIGLYHAKRLATPGQRIVLYAKDRGCTRPGCD
MUL_2371|M.ulcerans_Agy99 LARHAHHYLAVFD--RGEAIGLYHAKRLATPGQRIVLYAKDRGCTRPGCD
MAV_2352|M.avium_104 LARHAHHYLAVFD--NGKPLALYHTKRLASPGQRIVLYAKDRGCSHPGCD
MAB_0990c|M.abscessus_ATCC_199 MATHAHHYLAIFDD-HGRALYLGRSQRIASPDQRLVLHARDRGCTHPDCH
Mflv_4014|M.gilvum_PYR-GCK LAADAHHYLYVYDGHTGQSLYLGRAKRLANAAQRIVMHARDRGCTRPGCT
Mvan_3050|M.vanbaalenii_PYR-1 LAARAHHYLYVYDQHSGKSLYLGRAKRLANAAQRIVLHARDRGCTRPGCT
MSMEG_6573|M.smegmatis_MC2_155 LASQALHYLAVYDEHTGIPLYLGRARRTASAGQRLAIWARDRGCTRPGCT
TH_3287|M.thermoresistible__bu MAADAIHYLAVFDDHTERPLYLGRQKRIATADQRLICYARDGGCTAPGCG
:* * *** ::* .: * : :* *.. **: *:* **: *.*
Mb1179c|M.bovis_AF2122/97 APAYHSEVHHVTP-WTTTHRTDINDLTLACGPDNRLVEKG---WKTRKNA
Rv1148c|M.tuberculosis_H37Rv APAYHSEVHHVTP-WTTTHRTDINDLTLACGPDNRLVEKG---WKTRKNA
MMAR_3121|M.marinum_M VAGYQCEVHHVAA-WAISGRTDINQLTLACGPDHKLLEQG---WRTRKNA
MUL_2371|M.ulcerans_Agy99 VAGYQCEVHHVAA-WAISGRTDINQLTLACGPDHKLLEQG---WRTRKNA
MAV_2352|M.avium_104 VSGYYCEVHHVTG-YAKCGRTDIDQLTFACGGHHPLAEQG---WITRKNG
MAB_0990c|M.abscessus_ATCC_199 VPGYLCQAHHITE-WVHDGPTDIDNLTFACAPHHRLLGHG---WTTRKRK
Mflv_4014|M.gilvum_PYR-GCK VPGYWCQAHHASADWKDDGHTDIDDLTFACGPENRMIENTG--WTTAKNS
Mvan_3050|M.vanbaalenii_PYR-1 APGYWCQAHHASADFVDGGLTNIDDLTLACPCDHRMLDNTG--WRTRKNG
MSMEG_6573|M.smegmatis_MC2_155 ANGYRCQAHHATTDYAKGGLTDADALALACGCDNRLVGEAPNKWTTRINN
TH_3287|M.thermoresistible__bu EPGYHAETHHQPA-WEDGGLTDADHLFFACGPHHSGLTEGR--WQATITP
.* .:.** . : *: : * :** .: . * :
Mb1179c|M.bovis_AF2122/97 HGDTEWLPPPHLDH-GQPRINRYHHPAKILCEQDDDEP-----------H
Rv1148c|M.tuberculosis_H37Rv HGDTEWLPPPHLDH-GQPRINRYHHPAKILCEQDDDEP-----------H
MMAR_3121|M.marinum_M HGDTEWLPPPHLDH-GQPRTNTYHHPEKLLRDSADDDD---------EGH
MUL_2371|M.ulcerans_Agy99 HGDTEWLPPPHLDH-GQPRTNSYHHPEKLLRDSADDDD---------EGH
MAV_2352|M.avium_104 RGETEWIPPPHLER-GQPRVNSFHHPEDMLCDTEDQQDQQDQQDQADEED
MAB_0990c|M.abscessus_ATCC_199 DGTTEWIPPPQLALPGETRHDDIVDQCPHGVGSR----------------
Mflv_4014|M.gilvum_PYR-GCK RNQTEWIPPPDLET-GQHRVNGYHHPERHLLPHEEGEDS-----------
Mvan_3050|M.vanbaalenii_PYR-1 KNQTEWLPPPDLDT-GQHRVNGHHHPERYLLPEDD---------------
MSMEG_6573|M.smegmatis_MC2_155 HGQCEWIPPDLLDR-GQHRTNTYHHPETLLADINRDQKTDGDNREQHHTD
TH_3287|M.thermoresistible__bu TGRLAWTNDHHPPT-----VNHAHHPEELLRAHTDPPEDPG---------
. * : .
Mb1179c|M.bovis_AF2122/97 --------------------------------------------------
Rv1148c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3121|M.marinum_M GAA-----------------------------------------------
MUL_2371|M.ulcerans_Agy99 GAA-----------------------------------------------
MAV_2352|M.avium_104 GAA-----------------------------------------------
MAB_0990c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_4014|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3050|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6573|M.smegmatis_MC2_155 TGADTGTVHVNGHGEKPAIPPELLDQGQQRTAPYHQAEVPPVNTRDTRSS
TH_3287|M.thermoresistible__bu --------------------------------------------------
Mb1179c|M.bovis_AF2122/97 ------------------------------------
Rv1148c|M.tuberculosis_H37Rv ------------------------------------
MMAR_3121|M.marinum_M ------------------------------------
MUL_2371|M.ulcerans_Agy99 ------------------------------------
MAV_2352|M.avium_104 ------------------------------------
MAB_0990c|M.abscessus_ATCC_199 ------------------------------------
Mflv_4014|M.gilvum_PYR-GCK --------------------------STSRDCDDP-
Mvan_3050|M.vanbaalenii_PYR-1 ---------------------------LPEDDQGP-
MSMEG_6573|M.smegmatis_MC2_155 TTTRDANRHNGNGDRNSAENRNGPSKNAAGDDDEPR
TH_3287|M.thermoresistible__bu ------------------------------------