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IRTSVRYMAAEVGTALAALHAAMRDVLALPYTALSDADLLDVCAGIQDVRNLAPAVEHRAIAALSEQTTP AAIGAKSWPLVLATRLGISSKEARRRCADAAELGPRVSLTGEALAPKREHIAAAQADGALTPDHVTELFK FFTKCPDWVTYAEQCRLEEKLVTGAIGADPETVRQAVDHAVFLLDQDGPAPTDNPPTKPFGITFGPQQPD GSYHLRGKVSAEFKATFDPIDEKLAAPGMCNPTDQTPCISGTPSQQQIDHDERGAPERRHDAMLTAMRLL LAHKDLGQINGLPATLLITTTLQELEKAAGVAITAGGTKLSIPDLIRLASQALHYLAVYDEHTGVPLYLG RARRTASAGQRLAIWARDRGCTRPGCTANGYRCQAHHATTDYAKGGLTDADALALACGCDNRLVGEAPNK WTTRINNHGQCEWIPPQLLDRGQHRTNTYHHPETLLADIKSGFTDDTADSRSQTSKTTGSETHAKQAADT EPDTAIARGNDLSDRPAIPPELLGQNHQQPNTNHHPDTERGDARNSGATGHNQDHSRKNGDRNSGDASKG NNGNADGDDGESDCHPA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2663 | - | - | 100% (578) | hypothetical protein MSMEG_2663 |
| M. smegmatis MC2 155 | MSMEG_6573 | - | 0.0 | 81.17% (563) | hypothetical protein MSMEG_6573 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1159c | - | 3e-94 | 42.63% (448) | hypothetical protein Mb1159c |
| M. gilvum PYR-GCK | Mflv_3477 | - | 1e-115 | 45.49% (510) | hypothetical protein Mflv_3477 |
| M. tuberculosis H37Rv | Rv1128c | - | 3e-94 | 42.63% (448) | hypothetical protein Rv1128c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0394c | - | 2e-84 | 40.28% (432) | hypothetical protein MAB_0394c |
| M. marinum M | MMAR_1523 | - | 8e-90 | 42.41% (448) | hypothetical protein MMAR_1523 |
| M. avium 104 | MAV_2999 | - | 6e-98 | 42.73% (461) | hypothetical protein MAV_2999 |
| M. thermoresistible (build 8) | TH_3287 | - | 8e-51 | 31.76% (488) | PUTATIVE conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_2371 | - | 3e-86 | 39.82% (447) | hypothetical protein MUL_2371 |
| M. vanbaalenii PYR-1 | Mvan_5865 | - | 1e-111 | 44.14% (503) | hypothetical protein Mvan_5865 |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_0394c|M.abscessus_ATCC_199 -----------MSPIDDLLTTATAVVESS----FDELNNPELLSALRQLE
TH_3287|M.thermoresistible__bu MGQQFVTAGAARARVGELLAAVDAAYAEMRALCLDEVGTGFRLELAERLE
Mb1159c|M.bovis_AF2122/97 ---MCS----TREEITEAFASLATALSRVLGLTFDALTTPERLALLEHCE
Rv1128c|M.tuberculosis_H37Rv ---MCS----TREEITEAFASLATALSRVLGLTFDALTTPERLALLEHCE
MAV_2999|M.avium_104 MRGMSS----DREAVSAAFDAIDAALDDLLDCDYAALATREKLALLNRCE
MMAR_1523|M.marinum_M ---MSS---MSREEVVAAFDALDAVMARLQDLCFDGLTTPERLALLQRCE
MUL_2371|M.ulcerans_Agy99 ---MHSNGCSDRESVVATLDRLDRAVDALVEVSFEALTTPERLRVLERLE
Mflv_3477|M.gilvum_PYR-GCK ----MYVRIMSGGDLQARIAALRAAFDDVAAAEIDLLTRAELVAALDDLE
Mvan_5865|M.vanbaalenii_PYR-1 ----MYVRVMSRDALHAAVTALRATVDEVAACEADLCTRTELVAALDELE
MSMEG_2663|M.smegmatis_MC2_155 -MIRTSVRYMA-AEVGTALAALHAAMRDVLALPYTALSDADLLDVCAGIQ
: . . : :
MAB_0394c|M.abscessus_ATCC_199 IAQRKITAASHTLTARLVQRGSPVALGGTSFAEVLARYLSITTATARRRL
TH_3287|M.thermoresistible__bu TQCRINRGLMYRVFAQLADPPDEPAMVPAVRDRLWAR-LRITPGEVKRRL
Mb1159c|M.bovis_AF2122/97 TARRQLPSVEHTLINQIGEQSTEEELGGKLGLTLADR-LRITRSEAKRRV
Rv1128c|M.tuberculosis_H37Rv TARRQLPSVEHTLINQIGEQSTEEELGGKLGLTLADR-LRITRSEAKRRV
MAV_2999|M.avium_104 RLRRRLPAIEHPLINALARDATPAELGGRLSHAIAEA-TLISRAEAARRV
MMAR_1523|M.marinum_M VARRRLPSIEHPLINQLVEQAGEQELGGKLAAVLAGR-LRVSRGEASRRL
MUL_2371|M.ulcerans_Agy99 VVARRLPAAQYALVNQLDEQPGEAELGGRLAAVVASR-LRITRSEAGRRV
Mflv_3477|M.gilvum_PYR-GCK ELSCQLPAVGHRLLARLQVEATPQQLGAKSWSEVLRVRWRISTTEANRRL
Mvan_5865|M.vanbaalenii_PYR-1 TVGCRLPALSYRLLARLQAETTPPQMGAKSWKEVLAVRWRISTSEAHRRL
MSMEG_2663|M.smegmatis_MC2_155 DVRNLAPAVEHRAIAALSEQTTPAAIGAKSWPLVLATRLGISSKEARRRC
. : : : : :: . **
MAB_0394c|M.abscessus_ATCC_199 ADAAHLGPRRALTGEPLRPALPYVAHALREGRLGDEHVRIIRRFFDVLPD
TH_3287|M.thermoresistible__bu RVAALLRPRRRLSGPPLPPVLARVAGAVESGLLGEEHLRVITTVMAALPS
Mb1159c|M.bovis_AF2122/97 AEAADLGQRRALTGEPLPPLLTATAKAQRHGLIGDGHVEVIRAFVHRLPS
Rv1128c|M.tuberculosis_H37Rv AEAADLGQRRALTGEPLPPLLTATAKAQRHGLIGDGHVEVIRAFVHRLPS
MAV_2999|M.avium_104 HTAADLGPRVGLTGEPLPPLLAATAAAQREGSLGLEQVAVIRKFCHQLPG
MMAR_1523|M.marinum_M REAADLGPRRALTGEQLAPLLSATASAVRQGRIGAGHVRVIREFCGQVPA
MUL_2371|M.ulcerans_Agy99 AEAAEVGPRRALSGQPVGPVLTATAAALRQGVVGEGHVRVIRDFFRQLPA
Mflv_3477|M.gilvum_PYR-GCK TEAGLLAPRPSLTGPALPPQLAATAIAQARGLINAEHVAVIRKAVKKLPG
Mvan_5865|M.vanbaalenii_PYR-1 TEAAVLAPRQAMTGEALAPVLPATATAQAHGLINAEHVEVIRKTMAKVPG
MSMEG_2663|M.smegmatis_MC2_155 ADAAELGPRVSLTGEALAPKREHIAAAQADGALTPDHVTELFKFFTKCPD
*. : * ::* : * * * * : :: : *
MAB_0394c|M.abscessus_ATCC_199 AVDADTREAAEKQLASMGTEFGPEQLRAGADRIAALVNPDG-RFSDIDRA
TH_3287|M.thermoresistible__bu AVSVTDREAVEASLIAEAARSDAGIVRQVGRRIEEIFNPDG-HYDDQDRA
Mb1159c|M.bovis_AF2122/97 WVDLKTLEKAERDLAKQATQYRPDQLAKLAARIMDCLNPDG-DYTDEDRA
Rv1128c|M.tuberculosis_H37Rv WVDLKTLEKAERDLAKQATQYRPDQLAKLAARIMDCLNPDG-DYTDEDRA
MAV_2999|M.avium_104 WIDQATRERAEADLANQGTRYRPEQLAALAGTLADCLNPDG-LYRDEDRA
MMAR_1523|M.marinum_M EVDLETRERAEAHLARLAGQFRPDQLAKLAQRLMDCVNPDG-RYSDEDRA
MUL_2371|M.ulcerans_Agy99 GVDVGTRDRAEAHLAKLATQFRPDQLARLAGRLMDCLNPDG-RHSDEDRA
Mflv_3477|M.gilvum_PYR-GCK WVDVATREQFEVNLVRTAVGNGPKELRDAAELTLFLLDQDGPEPDDTERA
Mvan_5865|M.vanbaalenii_PYR-1 FVDTATRERIEVDLVRTAVGNGPKELKDSADRTLFLLDQDGPEPDERERA
MSMEG_2663|M.smegmatis_MC2_155 WVTYAEQCRLEEKLVTGAIGADPETVRQAVDHAVFLLDQDGPAPTDNPPT
: * * . . : .: ** : :
MAB_0394c|M.abscessus_ATCC_199 RRRGISIGRQGADGMSALSGLLDPETRAYFDAVLSKLAAPGMCDPRD---
TH_3287|M.thermoresistible__bu RRRGIHLGDQQRDGMSAISGWIDPQLRAYLEAVTAAVR-PGRHLPHTTTD
Mb1159c|M.bovis_AF2122/97 RRRGLTLGKQDVDGMSRLSGYVTPELRATIEAVWAKLAAPGMCNPEQ---
Rv1128c|M.tuberculosis_H37Rv RRRGLTLGKQDVDGMSRLSGYVTPELRATIEAVWAKLAAPGMCNPEQ---
MAV_2999|M.avium_104 RRRSLTLGNQHADGMSELRGLLTPELRATLEAVLAKLAAPGMCNPLD---
MMAR_1523|M.marinum_M RRRGLTLGRQGRDGMSRISGWLTPEARAGLDAVLAKLAAPGMCNPDD---
MUL_2371|M.ulcerans_Agy99 RRRGLSLGRQGLDGMSRISGWLTPEARAGLEAVWAKLAAPGMCNPED---
Mflv_3477|M.gilvum_PYR-GCK RKRGLTKGKQRPDGMIDLAGTLTPEAWAVLEVIFAKYAAPGMCNPAD---
Mvan_5865|M.vanbaalenii_PYR-1 RKRAVTKHKQREDGMVDVSATLTPEAWAVWEAIFAKFAAPGMCNPDD---
MSMEG_2663|M.smegmatis_MC2_155 KPFGITFGPQQPDGSYHLRGKVSAEFKATFDPIDEKLAAPGMCNPTD---
: .: * ** : . : .: * : : ** *
MAB_0394c|M.abscessus_ATCC_199 --------ESPMTEGEPDSAAAERDT---------------RTSAQRNHD
TH_3287|M.thermoresistible__bu TTGTTGTTETTGTAGTAGTAATAADTAADGVGDIDTGGVDLRSAAQRRHD
Mb1159c|M.bovis_AF2122/97 --------KAPCVNGAPSKEQARRDT---------------RSCPQRNHD
Rv1128c|M.tuberculosis_H37Rv --------KAPCVNGAPSKEQARRDT---------------RSCPQRNHD
MAV_2999|M.avium_104 --------ESPCVDGTPTEQAIEGDT---------------RSAAQRNHD
MMAR_1523|M.marinum_M --------ESPVVQAPAGADAVSRDR---------------RSVGQRHHD
MUL_2371|M.ulcerans_Agy99 --------EAAVVDGPVSRDAADRDS---------------RSVSQRQHD
Mflv_3477|M.gilvum_PYR-GCK --------PEPCTAGTPTQAQIDNDQ---------------RSLAQRQHD
Mvan_5865|M.vanbaalenii_PYR-1 --------PEPCTSGTPSQAQIDHDQ---------------RSLAQRQHD
MSMEG_2663|M.smegmatis_MC2_155 --------QTPCISGTPSQQQIDHDE---------------RGAPERRHD
. . * * :*.**
MAB_0394c|M.abscessus_ATCC_199 GLRACLRSTLASGKLGAHRGLPVTVVVSTTLRELQSAA-----------G
TH_3287|M.thermoresistible__bu GLTLGLKIAVASGRLGSHRGHPVTVIVRTTLGELNQAAHAVADPRVSMPG
Mb1159c|M.bovis_AF2122/97 ALNAGLRSLLTSGNLGQHNGLPASIIVTTTLKDLEAAA-----------G
Rv1128c|M.tuberculosis_H37Rv ALNAELRSLLTSGNLGQHNGLPASIIVTTTLKDLEAAA-----------G
MAV_2999|M.avium_104 GLLAGLRALLASGNLGQHNGLPASIIVTTTLADLETAA-----------G
MMAR_1523|M.marinum_M GLNAAVRALLASGDLGQHNGLPASIIVTTTLGELQRAC-----------G
MUL_2371|M.ulcerans_Agy99 GFNAALRAVLASGELGQHNGLPASIIVSTTLKELEAAA-----------G
Mflv_3477|M.gilvum_PYR-GCK ALVAVGRIALMSGELGQLNGLPVSIIIRTTLQDLESRA-----------G
Mvan_5865|M.vanbaalenii_PYR-1 ALLAGGRIALMSGQLGQLNGLPVSVIIRTTLQDLESRA-----------G
MSMEG_2663|M.smegmatis_MC2_155 AMLTAMRLLLAHKDLGQINGLPATLLITTTLQELEKAA-----------G
.: : : ** .* *.:::: *** :*: . *
MAB_0394c|M.abscessus_ATCC_199 RAISGSGNLVPIPDLIRMATHAFHYLTIFGDD-GRPLHLGRSKRIATPDQ
TH_3287|M.thermoresistible__bu PARTGGTGVLPMRELIRMAADAIHYLAVFDDHTERPLYLGRQKRIATADQ
Mb1159c|M.bovis_AF2122/97 AGLTGGGTILPISDVIRLARHANHYLAIFDRG--KALALYHTKRLASPAQ
Rv1128c|M.tuberculosis_H37Rv AGLTGGGTILPISDVIRLARHANHYLAIFDRG--KALALYHTKRLASPAQ
MAV_2999|M.avium_104 KGLTGGGTLLPMSDVIRLSRHAHHYLAIFDKG--KALALYHTKRLASPGQ
MMAR_1523|M.marinum_M RGLTGGGTVLPISDVIRLARHAHHYLAVFDRG--KAVGLYHAKRLATAGQ
MUL_2371|M.ulcerans_Agy99 RGLTGGGTLLPMSDVIRLARHAHHYLAVFDRG--EAIGLYHAKRLATPGQ
Mflv_3477|M.gilvum_PYR-GCK VGTTGGGTVVPIKDVIRMGGHANHYLAVFDRATGSALDLFRTRRVASPAQ
Mvan_5865|M.vanbaalenii_PYR-1 VGVTGGGTVMPIAEVIRMAGHANHYLAVFDRATGSALDLFRTRRIASPAQ
MSMEG_2663|M.smegmatis_MC2_155 VAITAGGTKLSIPDLIRLASQALHYLAVYDEHTGVPLYLGRARRTASAGQ
. :.. :.: ::**:. .* ***:::. .: * : :* *:. *
MAB_0394c|M.abscessus_ATCC_199 RIVLHAKDRGCSAPGCTVPGYLCQVHHVD-DWRDDGPTDIDNLTFACGPH
TH_3287|M.thermoresistible__bu RLICYARDGGCTAPGCGEPGYHAETHHQP-AWEDGGLTDADHLFFACGPH
Mb1159c|M.bovis_AF2122/97 RIMLYAKDSGCSAPGCDVPGYYCEVHHVT-PYAQCRNTDVNDLTLGCGGH
Rv1128c|M.tuberculosis_H37Rv RIMLYAKDSGCSAPGCDVPGYYCEVHHVT-PYAQCRNTDVNDLTLGCGGH
MAV_2999|M.avium_104 RIVLYAKDRGCTAPGCTVPGYYAEVHHCT-DYATCHTTDINDLTFACGPH
MMAR_1523|M.marinum_M RLVLYAKDRGCTRPGCDVPGYQCEVHHVA-AWATSGRTDIDQLTLACGPD
MUL_2371|M.ulcerans_Agy99 RIVLYAKDRGCTRPGCDVAGYQCEVHHVA-AWAISGRTDINQLTLACGPD
Mflv_3477|M.gilvum_PYR-GCK RVMLIARDGGCTKPCCTVGAYGCQVHHAETDYAHGGNTNIDELGLACGPD
Mvan_5865|M.vanbaalenii_PYR-1 RIMLIARDGGCTKPGCAVGAYGCQGHHVEADFAKGGNTNVDELGLACGPD
MSMEG_2663|M.smegmatis_MC2_155 RLAIWARDRGCTRPGCTANGYRCQAHHATTDYAKGGLTDADALALACGCD
*: *:* **: * * .* .: ** : *: : * :.** .
MAB_0394c|M.abscessus_ATCC_199 HRLLQQGW--TTRKRRSDGITEWIPPPHLDTGQSRTNDHHHPERFIR---
TH_3287|M.thermoresistible__bu HSGLTEGR--WQATITPTGRLAWTNDHHPPT----VNHAHHPEELLR---
Mb1159c|M.bovis_AF2122/97 HPLAERG---WTTRKNAHGDTEWLPPPHLDHGQPRVNTFHHPEKLL----
Rv1128c|M.tuberculosis_H37Rv HPLAERG---WTTRKNAHGDTEWLPPPHLDHGQPRVNTFHHPEKLL----
MAV_2999|M.avium_104 HRLLQPGA--WTTHKNARGETQWLPPPHLDRNQPRTNTFHHPEKLLRG--
MMAR_1523|M.marinum_M HKLLEQG---WRTRKNAHGDTEWLPPPHLDHGQPRTNTYHHPEKLLR---
MUL_2371|M.ulcerans_Agy99 HKLLEQG---WRTRKNAHGDTEWLPPPHLDHGQPRTNSYHHPEKLLR---
Mflv_3477|M.gilvum_PYR-GCK NRSVT--EGGWTTRMNDRCEVEWIPPPGLDTGQARVNTYHRPERLLA---
Mvan_5865|M.vanbaalenii_PYR-1 NRDVND-RGGWTTRMNDRCEVEWIPPPALDTGQARVNNYHRPERLLR---
MSMEG_2663|M.smegmatis_MC2_155 NRLVGEAPNKWTTRINNHGQCEWIPPQLLDRGQHRTNTYHHPETLLADIK
: * .* *:** ::
MAB_0394c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3287|M.thermoresistible__bu --------------------------------------------------
Mb1159c|M.bovis_AF2122/97 --------------------------------------------------
Rv1128c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_2999|M.avium_104 --------------------------------------------------
MMAR_1523|M.marinum_M --------------------------------------------------
MUL_2371|M.ulcerans_Agy99 --------------------------------------------------
Mflv_3477|M.gilvum_PYR-GCK ---PPEDPEPP-DQTRSTATEPAAVQAID---DPEAQ-------------
Mvan_5865|M.vanbaalenii_PYR-1 ---PPDDPEPPGDNTIAAEAASAGTDQADPRGDAESD-------------
MSMEG_2663|M.smegmatis_MC2_155 SGFTDDTADSRSQTSKTTGSETHAKQAADTEPDTAIARGNDLSDRPAIPP
MAB_0394c|M.abscessus_ATCC_199 -----------RF-------------------------------------
TH_3287|M.thermoresistible__bu -----------AHTDPPEDPG-----------------------------
Mb1159c|M.bovis_AF2122/97 ------------ADDEGDP-------------------------------
Rv1128c|M.tuberculosis_H37Rv ------------ADDEGDP-------------------------------
MAV_2999|M.avium_104 --------EDGGEDDDGDDDEAA---------------------------
MMAR_1523|M.marinum_M ----------DSAADEGEEGG-----------------------------
MUL_2371|M.ulcerans_Agy99 ----------DSADDDDEGHGAA---------------------------
Mflv_3477|M.gilvum_PYR-GCK --------APRPADDPGEPGGPAPPEGEAA--------------------
Mvan_5865|M.vanbaalenii_PYR-1 --------APQPTDDPGEPGGPAPPGDQAA--------------------
MSMEG_2663|M.smegmatis_MC2_155 ELLGQNHQQPNTNHHPDTERGDARNSGATGHNQDHSRKNGDRNSGDASKG
MAB_0394c|M.abscessus_ATCC_199 -----------------
TH_3287|M.thermoresistible__bu -----------------
Mb1159c|M.bovis_AF2122/97 -----------------
Rv1128c|M.tuberculosis_H37Rv -----------------
MAV_2999|M.avium_104 -----------------
MMAR_1523|M.marinum_M -----------------
MUL_2371|M.ulcerans_Agy99 -----------------
Mflv_3477|M.gilvum_PYR-GCK -----------------
Mvan_5865|M.vanbaalenii_PYR-1 -----------------
MSMEG_2663|M.smegmatis_MC2_155 NNGNADGDDGESDCHPA