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SVPLSRLSNMSSKKEVIAALDAVDRAHRAAAALPFQSLAPADQRALLVRLDAVAKQLAVTQRRLLGQMVA GPPPVELAGAPWAEVLARRLRISVGEAQRRISEAAAPIDS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1097 | - | - | 100% (111) | hypothetical protein Mflv_1097 |
| M. gilvum PYR-GCK | Mflv_4397 | - | 2e-07 | 39.33% (89) | hypothetical protein Mflv_4397 |
| M. gilvum PYR-GCK | Mflv_1835 | - | 4e-07 | 38.67% (75) | hypothetical protein Mflv_1835 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1179c | - | 5e-08 | 35.51% (107) | hypothetical protein Mb1179c |
| M. tuberculosis H37Rv | Rv1148c | - | 5e-08 | 35.51% (107) | hypothetical protein Rv1148c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0990c | - | 3e-07 | 30.68% (88) | hypothetical protein MAB_0990c |
| M. marinum M | MMAR_3121 | - | 7e-12 | 41.05% (95) | hypothetical protein MMAR_3121 |
| M. avium 104 | MAV_3664 | - | 1e-09 | 43.96% (91) | hypothetical protein MAV_3664 |
| M. smegmatis MC2 155 | MSMEG_2663 | - | 7e-07 | 32.97% (91) | hypothetical protein MSMEG_2663 |
| M. thermoresistible (build 8) | TH_3740 | - | 1e-07 | 34.04% (94) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_2371 | - | 4e-12 | 40.00% (95) | hypothetical protein MUL_2371 |
| M. vanbaalenii PYR-1 | Mvan_5720 | - | 6e-37 | 78.35% (97) | hypothetical protein Mvan_5720 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1097|M.gilvum_PYR-GCK --------------------MSVPLSRLSNMSSKKEVIAALDAVDRAHRA
Mvan_5720|M.vanbaalenii_PYR-1 ------------------------------MSSKKEWIAALDAVDHAHRA
Mb1179c|M.bovis_AF2122/97 MSETFCLTDHSEPMTARFLSVVLRRIRGMRSDTREEISAALDAYHASLSR
Rv1148c|M.tuberculosis_H37Rv MSETFCLTDHSEPMTARFLSVVLRRIRGMRSDTREEISAALDAYHASLSR
MMAR_3121|M.marinum_M -------------------------MHSNGCSDRESVVATLDRLDRAVDA
MUL_2371|M.ulcerans_Agy99 -------------------------MHSNGCSDRESVVATLDRLDRAVDA
MAB_0990c|M.abscessus_ATCC_199 -------------------------------------MSSIGVVEAAVDA
MAV_3664|M.avium_104 -------------------------MHSIEVP--AEVRAALDALDTADAA
MSMEG_2663|M.smegmatis_MC2_155 ------------------------MIRTSVRYMAAEVGTALAALHAAMRD
TH_3740|M.thermoresistible__bu -----------------MDSNISGPEPSGAPSARAQWAAVLDELEAAEAA
: : . :
Mflv_1097|M.gilvum_PYR-GCK AAALPFQSLAPADQRALLVRLDAVAKQLAVTQRRLLGQMVAGPPPVELAG
Mvan_5720|M.vanbaalenii_PYR-1 VAGLPFHTLQPADQRALLVRLDALEKLLATRQRQLLAHMVGGPPPVEFAG
Mb1179c|M.bovis_AF2122/97 VLDLKCDALTTPELLACLQRLEVERRRQGAAEHALINQLAGQACEEELGG
Rv1148c|M.tuberculosis_H37Rv VLDLKCDALTTPELLACLQRLEVERRRQGAAEHALINQLAGQACEEELGG
MMAR_3121|M.marinum_M LVEVSFEALTTPERLRVLERLEVVARRLPVAQYALLNQLDEQAGEAELGG
MUL_2371|M.ulcerans_Agy99 LVEVSFEALTTPERLRVLERLEVVARRLPAAQYALVNQLDEQPGEAELGG
MAB_0990c|M.abscessus_ATCC_199 FCAESIEDLTAGEALAMLARLKVVQRRLASRGLGLVSAVTGQASPMQLGG
MAV_3664|M.avium_104 IRALDFDALHPVVRLRALERMEASRRRQIAVSHDVIAGLAGE-GPANVGG
MSMEG_2663|M.smegmatis_MC2_155 VLALPYTALSDADLLDVCAGIQDVRNLAPAVEHRAIAALSEQTTPAAIGA
TH_3740|M.thermoresistible__bu LLRAPVHSLSGPQLLELIRRLEILERRTRAHQQRLLGRLVAESVAGSVAG
* :. . : : ...
Mflv_1097|M.gilvum_PYR-GCK APWAEVLARRLRISVGEAQRRISEAAAPIDS-------------------
Mvan_5720|M.vanbaalenii_PYR-1 APWAEVLARRLRISVGEAKRRIEDAGAVPT--------------------
Mb1179c|M.bovis_AF2122/97 T-LRTALANRLHITPGEASRRIAEAEDLGERRALTGEPLPAQLTATAAAQ
Rv1148c|M.tuberculosis_H37Rv T-LRTALANRLHITPGEASRRIAEAEDLGERRALTGEPLPAQLTATAAAQ
MMAR_3121|M.marinum_M R-LAAVVASRLRITRSEAGRRVAEAADVGPRRALSGQPVGPVLTATAAAL
MUL_2371|M.ulcerans_Agy99 R-LAAVVASRLRITRSEAGRRVAEAAEVGPRRALSGQPVGPVLTATAAAL
MAB_0990c|M.abscessus_ATCC_199 TSYAEVLSRRMHMGKRAARRRIADAELLAPRRAITGEQLAPQLPHTAQAL
MAV_3664|M.avium_104 P-VHKVIADRLRISYAEACRRLREAKQLSPRLTLTGQELPPELPATAGVW
MSMEG_2663|M.smegmatis_MC2_155 KSWPLVLATRLGISSKEARRRCADAAELGPRVSLTGEALAPKREHIAAAQ
TH_3740|M.thermoresistible__bu S-----VGKALRISPAEAHRRITEARGLAS--------------------
:. : : * ** :*
Mflv_1097|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5720|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb1179c|M.bovis_AF2122/97 REGKIGREHIKEIQAFFKELSAAVDLGIREAAEAQLAELATSRRPDHLHG
Rv1148c|M.tuberculosis_H37Rv REGKIGREHIKEIQAFFKELSAAVDLGIREAAEAQLAELATSRRPDHLHG
MMAR_3121|M.marinum_M RQGVVGEGHVRVIRDFFRRLPAGVDVGTRDRAEAHLAKLATQFRPDQLAR
MUL_2371|M.ulcerans_Agy99 RQGVVGEGHVRVIRDFFRQLPAGVDVGTRDRAEAHLAKLATQFRPDQLAR
MAB_0990c|M.abscessus_ATCC_199 GRGDIGEEHLRIIRHFFDRLPVVVDAATREAAEAQLAVMATQFRPEALRV
MAV_3664|M.avium_104 REGMLDGQHLRVIEKFVRDLPETTPVRALEEAERFLAHQATLLRPDQLEK
MSMEG_2663|M.smegmatis_MC2_155 ADGALTPDHVTELFKFFTKCPDWVTYAEQCRLEEKLVTGAIGADPETVRQ
TH_3740|M.thermoresistible__bu --------------------------------------------------
Mflv_1097|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5720|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb1179c|M.bovis_AF2122/97 LATQLMDWLHPDG-NFSDQERARKRGITMGKQEFDGMSRISGLLTPELRA
Rv1148c|M.tuberculosis_H37Rv LATQLMDWLHPDG-NFSDQERARKRGITMGKQEFDGMSRISGLLTPELRA
MMAR_3121|M.marinum_M LAGRLMDCLNPDG-RHSDEDRARRRGLSLGRQGLDGMSRISGWLTPEARA
MUL_2371|M.ulcerans_Agy99 LAGRLMDCLNPDG-RHSDEDRARRRGLSLGRQGLDGMSRISGWLTPEARA
MAB_0990c|M.abscessus_ATCC_199 GADRMMALLNPDG-QFSDADRARRRGITIGPQGFDGMSAISGLLDPETRA
MAV_3664|M.avium_104 VAHQCALRINPDG-KFSDADRARQRGFTWCGQRADEMSLGKLWASPELRA
MSMEG_2663|M.smegmatis_MC2_155 AVDHAVFLLDQDGPAPTDNPPTKPFGITFGPQQPDGSYHLRGKVSAEFKA
TH_3740|M.thermoresistible__bu --------------------------------------------------
Mflv_1097|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5720|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb1179c|M.bovis_AF2122/97 TIEAVLAKLAAPGACNPDDQTPLVDDTPDADAVRRDTRSQAQRNHDAFLA
Rv1148c|M.tuberculosis_H37Rv TIEAVLAKLAAPGACNPDDQTPLVDDTPDADAVRRDTRSQAQRNHDAFLA
MMAR_3121|M.marinum_M GLEAVWAKLAAPGMCNPEDEAAVVDGPVSPDAADRDSRSVGQRQHDGFNA
MUL_2371|M.ulcerans_Agy99 GLEAVWAKLAAPGMCNPEDEAAVVDGPVSRDAADRDSRSVSQRQHDGFNA
MAB_0990c|M.abscessus_ATCC_199 YLDAVFAKLAAPGMCNPNDQSPLVDGQPADDAAERDTRTVAQRHHDALRA
MAV_3664|M.avium_104 NLDAWLARFAAPGMCNPDDEVPCVAGEPDEESATKDSRTPAQRQHDALNA
MSMEG_2663|M.smegmatis_MC2_155 TFDPIDEKLAAPGMCNPTDQTPCISGTPSQQQIDHDERGAPERRHDAMLT
TH_3740|M.thermoresistible__bu --------------------------------------------------
Mflv_1097|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5720|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb1179c|M.bovis_AF2122/97 ALRGLLASGELGQHKGLPVTIVVSTTLKELEAATGKGVTGGGSRVPMSDL
Rv1148c|M.tuberculosis_H37Rv ALRGLLASGELGQHKGLPVTIVVSTTLKELEAATGKGVTGGGSRVPMSDL
MMAR_3121|M.marinum_M ALRAVLASGELGQHNGLPASIIVSTTLKELEAAAGRGLTGGGTLLPMSDV
MUL_2371|M.ulcerans_Agy99 ALRAVLASGELGQHNGLPASIIVSTTLKELEAAAGRGLTGGGTLLPMSDV
MAB_0990c|M.abscessus_ATCC_199 ALRSTLVSTELGSHHGLPVTVVVTTTLKELEDAAGIAITGAGTRLPMRDL
MAV_3664|M.avium_104 LVRGRLGDPKLGLHNGLPVTVIVSTTLRELTTGAGRAVTGGGTLLPMRDV
MSMEG_2663|M.smegmatis_MC2_155 AMRLLLAHKDLGQINGLPATLLITTTLQELEKAAGVAITAGGTKLSIPDL
TH_3740|M.thermoresistible__bu --------------------------------------------------
Mflv_1097|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5720|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb1179c|M.bovis_AF2122/97 IRMASHANHYLALFD--GAKPLALYHTKRLASPAQRIMLYAKDRGCSRPG
Rv1148c|M.tuberculosis_H37Rv IRMASHANHYLALFD--GAKPLALYHTKRLASPAQRIMLYAKDRGCSRPG
MMAR_3121|M.marinum_M IRLARHAHHYLAVFD--RGEAIGLYHAKRLATPGQRIVLYAKDRGCTRPG
MUL_2371|M.ulcerans_Agy99 IRLARHAHHYLAVFD--RGEAIGLYHAKRLATPGQRIVLYAKDRGCTRPG
MAB_0990c|M.abscessus_ATCC_199 IRMATHAHHYLAIFDD-HGRALYLGRSQRIASPDQRLVLHARDRGCTHPD
MAV_3664|M.avium_104 IRMARHAYHYLAVFDEHSSRPLYLGRSRRVASPDQRVVLYAKDRGCTHPG
MSMEG_2663|M.smegmatis_MC2_155 IRLASQALHYLAVYDEHTGVPLYLGRARRTASAGQRLAIWARDRGCTRPG
TH_3740|M.thermoresistible__bu --------------------------------------------------
Mflv_1097|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5720|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb1179c|M.bovis_AF2122/97 CDAPAYHSEVHHVT-PWTTTHRTDINDLTLACGPDNRLVEKG---WKTRK
Rv1148c|M.tuberculosis_H37Rv CDAPAYHSEVHHVT-PWTTTHRTDINDLTLACGPDNRLVEKG---WKTRK
MMAR_3121|M.marinum_M CDVAGYQCEVHHVA-AWAISGRTDINQLTLACGPDHKLLEQG---WRTRK
MUL_2371|M.ulcerans_Agy99 CDVAGYQCEVHHVA-AWAISGRTDINQLTLACGPDHKLLEQG---WRTRK
MAB_0990c|M.abscessus_ATCC_199 CHVPGYLCQAHHIT-EWVHDGPTDIDNLTFACAPHHRLLGHG---WTTRK
MAV_3664|M.avium_104 CDAPGYWCEVHHLD-EWATGGLTDVDNLTFACGTHHKLIENG---WRTNK
MSMEG_2663|M.smegmatis_MC2_155 CTANGYRCQAHHATTDYAKGGLTDADALALACGCDNRLVGEAPNKWTTRI
TH_3740|M.thermoresistible__bu --------------------------------------------------
Mflv_1097|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5720|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb1179c|M.bovis_AF2122/97 NAHGDTEWLPPPHLDHGQPRINRYHHPAKILCE------QDDDEPH----
Rv1148c|M.tuberculosis_H37Rv NAHGDTEWLPPPHLDHGQPRINRYHHPAKILCE------QDDDEPH----
MMAR_3121|M.marinum_M NAHGDTEWLPPPHLDHGQPRTNTYHHPEKLLRDSA----DDDDEGHGAA-
MUL_2371|M.ulcerans_Agy99 NAHGDTEWLPPPHLDHGQPRTNSYHHPEKLLRDSA----DDDDEGHGAA-
MAB_0990c|M.abscessus_ATCC_199 RKDGTTEWIPPPQLAL--PGETRHDDIVDQCPHGV----GSR--------
MAV_3664|M.avium_104 LADGRTAWIPPPQWDRG-ARTNEFHHPERAFDG------EDP--------
MSMEG_2663|M.smegmatis_MC2_155 NNHGQCEWIPPQLLDRGQHRTNTYHHPETLLADIKSGFTDDTADSRSQTS
TH_3740|M.thermoresistible__bu --------------------------------------------------
Mflv_1097|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5720|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb1179c|M.bovis_AF2122/97 --------------------------------------------------
Rv1148c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3121|M.marinum_M --------------------------------------------------
MUL_2371|M.ulcerans_Agy99 --------------------------------------------------
MAB_0990c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_3664|M.avium_104 --------------------------------------------------
MSMEG_2663|M.smegmatis_MC2_155 KTTGSETHAKQAADTEPDTAIARGNDLSDRPAIPPELLGQNHQQPNTNHH
TH_3740|M.thermoresistible__bu --------------------------------------------------
Mflv_1097|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5720|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb1179c|M.bovis_AF2122/97 --------------------------------------------------
Rv1148c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3121|M.marinum_M --------------------------------------------------
MUL_2371|M.ulcerans_Agy99 --------------------------------------------------
MAB_0990c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_3664|M.avium_104 --------------------------------------------------
MSMEG_2663|M.smegmatis_MC2_155 PDTERGDARNSGATGHNQDHSRKNGDRNSGDASKGNNGNADGDDGESDCH
TH_3740|M.thermoresistible__bu --------------------------------------------------
Mflv_1097|M.gilvum_PYR-GCK --
Mvan_5720|M.vanbaalenii_PYR-1 --
Mb1179c|M.bovis_AF2122/97 --
Rv1148c|M.tuberculosis_H37Rv --
MMAR_3121|M.marinum_M --
MUL_2371|M.ulcerans_Agy99 --
MAB_0990c|M.abscessus_ATCC_199 --
MAV_3664|M.avium_104 --
MSMEG_2663|M.smegmatis_MC2_155 PA
TH_3740|M.thermoresistible__bu --